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Journal articles on the topic 'Dicarboxylic'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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1

Vamecq, J., E. de Hoffmann, and F. Van Hoof. "The microsomal dicarboxylyl-CoA synthetase." Biochemical Journal 230, no. 3 (1985): 683–93. http://dx.doi.org/10.1042/bj2300683.

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Dicarboxylic acids are products of the omega-oxidation of monocarboxylic acids. We demonstrate that in rat liver dicarboxylic acids (C5-C16) can be converted into their CoA esters by a dicarboxylyl-CoA synthetase. During this activation ATP, which cannot be replaced by GTP, is converted into AMP and PPi, both acting as feedback inhibitors of the reaction. Thermolabile at 37 degrees C, and optimally active at pH 6.5, dicarboxylyl-CoA synthetase displays the highest activity on dodecanedioic acid (2 micromol/min per g of liver). Cell-fractionation studies indicate that this enzyme belongs to the

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2

Vamecq, J., J. P. Draye, and J. Brison. "Rat liver metabolism of dicarboxylic acids." American Journal of Physiology-Gastrointestinal and Liver Physiology 256, no. 4 (1989): G680—G688. http://dx.doi.org/10.1152/ajpgi.1989.256.4.g680.

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Recently, we demonstrated in rat liver that dicarboxylic acids containing more than five carbons can be activated by a microsomal dicarboxylyl-CoA synthetase (J. Vamecq, E. de Hoffmann, and F. Van Hoof. Biochem. J. 230: 683-693, 1985). The products of this reaction, dicarboxylyl-CoA esters, were found to be substrates for an H2O2-generating dicarboxylyl-CoA oxidase. In the present work we report that 1) the catalytic center or the essential domains of dicarboxylyl-CoA synthetase are located at the cytosolic aspect of the endoplasmic reticulum membrane; 2) dicarboxylyl-CoA oxidase is optimally

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3

Stephanou, E. G. "?,?-Dicarboxylic acid salts and?,?-dicarboxylic acids." Naturwissenschaften 79, no. 3 (1992): 128–31. http://dx.doi.org/10.1007/bf01131541.

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4

Tonsgard, J. H., and S. C. Meredith. "Characterization of the binding sites for dicarboxylic acids on bovine serum albumin." Biochemical Journal 276, no. 3 (1991): 569–75. http://dx.doi.org/10.1042/bj2760569.

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Dicarboxylic acids are prominent features of several diseases, including Reye's syndrome and inborn errors of mitochondrial and peroxisomal fatty acid oxidation. Moreover, dicarboxylic acids are potentially toxic to cellular processes. Previous studies [Tonsgard, Mendelson & Meredith (1988) J. Clin. Invest. 82, 1567-1573] demonstrated that long-chain dicarboxylic acids have a single high-affinity binding site and between one and three lower-affinity sites on albumin. Medium-chain-length dicarboxylic acids have a single low-affinity site. We further characterized dicarboxylic acid binding t

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5

Kamoun, P., Ph Parvy, D. Rabier, J. Bardet, T. Billette de Villemeur, and J. M. Saudubray. "Dicarboxylic aminoaciduria." Journal of Inherited Metabolic Disease 17, no. 6 (1994): 758. http://dx.doi.org/10.1007/bf00712024.

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6

Kropacheva, Polina P., Larisa G. Kubarskaya, and Mariia A. Brusina. "Bis-methylamides of 1,2-dialkyl substituted imidazole-4,5-dicarboxylic acids: preparation and antinociceptive activity." Medical academic journal 24, no. 3 (2024): 87–94. https://doi.org/10.17816/maj630226.

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BACKGROUND: Searching for substances with high analgesic activity is one of the main problems of modern medicine. N-methyl-D-aspartate receptors present in all areas of the central nervous system responsible for reaction on pain stimulation. Moreover, peripheral glutamate receptors may be directly involved in the genesis of pain reactions. Therefore, it is of interest to search for new analgesics among N-methyl-D-aspartate receptor ligands. AIM: To develop a preparative method of synthesis and to investigate the antinociceptive activity of 1,2-dialkylimidazole-4,5-dicarboxylic acids bis-methyl

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7

Modrzakowski, Malcolm C., and William R. Finnerty. "Intermediary metabolism of Acinetobacter grown on dialkyl ethers." Canadian Journal of Microbiology 35, no. 11 (1989): 1031–36. http://dx.doi.org/10.1139/m89-171.

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The microbial dissimilation of long-chain dialkyl ethers by Acinetobacter sp. H01-N involved a terminal methyl group oxidation of the dialkyl ether substrates, resulting in the formation of ether oxygen containing fatty acids of corresponding chain length. An internal carbon–carbon scission of the dialkyl ethers resulted in the formation of end-product ether fatty acids and corresponding dicarboxylic acids. Cellular carbon and energy were derived from the subsequent metabolism of the dicarboxylic acids. Dicarboxylic acid oxidation, activation, and identification of cellular dicarboxylic acids

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8

Ranea-Robles, Pablo, and Sander M. Houten. "The biochemistry and physiology of long-chain dicarboxylic acid metabolism." Biochemical Journal 480, no. 9 (2023): 607–27. http://dx.doi.org/10.1042/bcj20230041.

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Mitochondrial β-oxidation is the most prominent pathway for fatty acid oxidation but alternative oxidative metabolism exists. Fatty acid ω-oxidation is one of these pathways and forms dicarboxylic acids as products. These dicarboxylic acids are metabolized through peroxisomal β-oxidation representing an alternative pathway, which could potentially limit the toxic effects of fatty acid accumulation. Although dicarboxylic acid metabolism is highly active in liver and kidney, its role in physiology has not been explored in depth. In this review, we summarize the biochemical mechanism of the forma

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9

RAJINDER, PARSHAD, and S. SHARMA K. "Photolysis of Substituted Benzylidineacenaphthenones." Journal Of Indian Chemical Society Vol. 66, Feb 1989 (1989): 106–9. https://doi.org/10.5281/zenodo.6302322.

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Department of Chemistry, M. D. University, Rohtak 124 001 <em>Manuscript received 7 March 1988, revised 27 September 1988, accepted 4 October 1988</em> Substituted benzylidineacenaphthenones were photolysed In benzene in presence of air.  Cyclodehydrogenation led to substituted-benzochrysenes as well as photo-oxidative cleavage of benzylidine double bond leading to Papbthalene-1,8-dicarboxylic acid anhydride as the major product Photolysis of acuaphthenone also gave naphthalene-1,8-dicarboxyli acid anhydride under the same condition In which the ben

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10

Elix, JA, R. Naidu, and JR Laundon. "A Synthesis of the Lichen Dibenzofuran Pannaric Acid 2-Methyl Ester and Its Isomer 3-O-Methylpannaric Acid." Australian Journal of Chemistry 45, no. 4 (1992): 785. http://dx.doi.org/10.1071/ch9920785.

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A total synthesis of pannaric acid 2-methyl ester (2-methyl hydrogen 3,9-dihydroxy-1,7-dimethyldibenzofuran-2,6-dicarboxylae) (1) and 3-O-methylpannaric acid (9-hydroxy- 3-methoxy-1,7-dimethyldibemofuran-2,6-dicarboxylic acid) (2) has been achieved through a biomimetic-type approach by using palladium(n) acetate in the key cyclization step. The acid (1) was shown to be identical to a major metabolite of the lichen Roccella capensis and a minor or trace constituent of the lichens Leproloma diffusum and L. vouauxii.

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11

He, Xiang, Feng Qian, and Yao Li. "Characterization of Organic Acids with Different Atmospheric Particle Sizes." Advanced Materials Research 599 (November 2012): 14–22. http://dx.doi.org/10.4028/www.scientific.net/amr.599.14.

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Atmospheric particulate samples were collected during January, February, April and May 2012, separately. Twenty-one fatty acids and seven dicarboxylic acids were measured by GC-MS. The results show that average mass concentrations of fatty acids are 809.24ng/m³, 545.34ng/m³, 386.96ng/m³ and dicarboxylic acids are 215.14 ng/m³, 156.45 ng/m³, 111.43 ng/m³ in PM10, PM2.5, PM1, respectively. Fatty acids and dicarboxylic acids concentrate mainly in the PM1. C11-C24 of fatty acids exhibit a significant even carbon predominances, but dicarboxylic acids present no parity preponderance. In the fatty ac

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12

Harrison, Faith H., and Caroline S. Harwood. "The pimFABCDE operon from Rhodopseudomonas palustris mediates dicarboxylic acid degradation and participates in anaerobic benzoate degradation." Microbiology 151, no. 3 (2005): 727–36. http://dx.doi.org/10.1099/mic.0.27731-0.

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Bacteria in anoxic environments typically convert aromatic compounds derived from pollutants or green plants to benzoyl-CoA, and then to the C7 dicarboxylic acid derivative 3-hydroxypimelyl-CoA. Inspection of the recently completed genome sequence of the purple nonsulfur phototroph Rhodopseudomonas palustris revealed one predicted cluster of genes for the β-oxidation of dicarboxylic acids. These genes, annotated as pimFABCDE, are predicted to encode acyl-CoA ligase, enoyl-CoA hydratase, acyl-CoA dehydrogenase and acyl-CoA transferase enzymes, which should allow the conversion of odd-chain dica

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13

Shinde, Sunil B., and Raj M. Deshpande. "Catalytic Hydrogenation Products of Aromatic and Aliphatic Dicarboxylic Acids." Asian Journal of Chemistry 31, no. 5 (2019): 1137–42. http://dx.doi.org/10.14233/ajchem.2019.21921.

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Hydrogenation of aromatic dicarboxylic acids gave 100 % selectivity to respective cyclohexane dicarboxylic acid with 5 % Pd/C catalyst. 5 % Ru/C catalyst was observed to give over hydrogenation products at 493 K and at lower temperature (453 K) the selectivity for cyclohexane dicarboxylic acids was increased. Hydrogenation of phthalic acid with Ru-Sn/Al2O3 catalyst was observed to give phthalide instead of 1,2-benzene dimethanol or 2-hydroxy methyl benzoic acid. Ru-Sn/Al2O3 catalyst selectively hydrogenated the carboxylic group of cyclohexane dicarboxylic acids to give cyclohexane dimethanol.

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14

Menshikov, Maxim A., and Maria A. Brusina. "Preparation of 1,1´-(alkyldiyl)-bis-(2-alkylimidazole-4,5-dicarboxylic) acids." Medical academic journal 24, no. 3 (2024): 95–102. https://doi.org/10.17816/maj631409.

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BACKGROUND: Alkyl-bis-imidazole-4,5-dicarboxylic acids can be used both in the production of polymers with pronounced fluorescent properties and as potential antiviral agents. However, there is currently no simple method for the synthesis of alkyl-bis-imidazole-4,5-dicarboxylic acids with a wide range of substituents at both 1, 1ʹ and 2, 2ʹ positions. Therefore, the search for alternative, easier ways to synthesize compounds of this series remains relevant. AIM: To develop a method for obtaining 2-substituted bis-imidazole-4,5-dicarboxylic acids connected at positions 1, 1ʹ by an alkyl chain o

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15

Bate, Andrea L., Thomas P. Carter, and John W. Wheeler. "Facile Synthesis of Some Novel Dicarboxylic Acid Crown Ethers." Journal of Chemical Research 23, no. 1 (1999): 58–59. http://dx.doi.org/10.1177/174751989902300135.

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Two procedures for the synthesis of a series of novel dicarboxylic acid functionalised aza-crown ethers from dicarboxylic acid anhydrides and 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane are reported.

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16

Vašš, František, and Jozef Lustoň. "Functional Derivatives of Sterically Hindered Amines. Polyalkylpiperidine Diesters." Collection of Czechoslovak Chemical Communications 60, no. 9 (1995): 1529–35. http://dx.doi.org/10.1135/cccc19951529.

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Several diesters of dicarboxylic acids with pendant polyalkylpiperidine structural units were prepared from α-bromo and α,α'-dibromo substituted aliphatic dicarboxylic acid diesters by a nucleophilic replacement reaction with 2,2,6,6-tetramethyl-4-hydroxypiperidine, 1,2,2,6,6-pentamethyl-4-hydroxypiperidine, and 2,2,6,6-tetramethyl-4-aminopiperidine, by a nucleophilic addition of amino derivative to the α,β-unsaturated dicarboxylic acid diester and by an acid catalyzed condensation of 2,2,6,6-tetramethyl-4-oxopiperidine with diethyl bis(hydroxymethyl)malonate.

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17

Kumar B., Satheesh, Balakondareddy Sana, G. Unnikrishnan, Tushar Jana, and Santhosh Kumar K. S. "Polybenzimidazole co-polymers: their synthesis, morphology and high temperature fuel cell membrane properties." Polymer Chemistry 11, no. 5 (2020): 1043–54. http://dx.doi.org/10.1039/c9py01403a.

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Polybenzimidazole (PBI) random co-polymers containing alicyclic and aromatic backbones were synthesized using two different dicarboxylic acids (viz., cyclohexane dicarboxylic acid and terephthalic acid) by varying their molar ratios.

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18

Roy, Siddhartha, Desh Deepak Singh, and M. Vijayan. "X-ray studies on crystalline complexes involving amino acids and peptides. XLII. Adipic acid complexes of L- and DL-arginine and supramolecular association in arginine–dicarboxylic acid complexes." Acta Crystallographica Section B Structural Science 61, no. 1 (2005): 89–95. http://dx.doi.org/10.1107/s0108768104030010.

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The adipic acid complexes of DL-arginine and L-arginine are made up of zwitterionic, singularly positively charged arginium ions and doubly negatively charged adipate ions, with a 2:1 stoichiometry. One of the two crystallographically independent arginium ions in the L-arginine complex has a conformation hitherto unobserved in crystal structures containing the amino acid. In the present study the structural data on arginine complexes of saturated dicarboxylic acids with 0–5 C atoms separating the two carboxyl functions are given. In terms of molecular aggregation, formic and acetic acid comple

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19

Zhang, Zhenglin, Mohamed I. Hashim, Chia-Hua Wu, Judy I. Wu, and Ognjen Š. Miljanić. "Discrimination of dicarboxylic acids via assembly-induced emission." Chemical Communications 54, no. 82 (2018): 11578–81. http://dx.doi.org/10.1039/c8cc06689b.

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Dicarboxylic acids are important chemicals in human metabolism and various industries. A triazine-based AIEgen can recognize dicarboxylic acids with selectivity based on the relative position of the two –COOH groups.

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20

Sato, Kei, Fumikazu Ikemori, Sathiyamurthi Ramasamy, et al. "Four- and Five-Carbon Dicarboxylic Acids Present in Secondary Organic Aerosol Produced from Anthropogenic and Biogenic Volatile Organic Compounds." Atmosphere 12, no. 12 (2021): 1703. http://dx.doi.org/10.3390/atmos12121703.

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To better understand precursors of dicarboxylic acids in ambient secondary organic aerosol (SOA), we studied C4–C9 dicarboxylic acids present in SOA formed from the oxidation of toluene, naphthalene, α-pinene, and isoprene. C4–C9 dicarboxylic acids present in SOA were analyzed by offline derivatization gas chromatography–mass spectrometry. We revealed that C4 dicarboxylic acids including succinic acid, maleic acid, fumaric acid, malic acid, DL-tartaric acid, and meso-tartaric acid are produced by the photooxidation of toluene. Since meso-tartaric acid barely occurs in nature, it is a potential

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21

Shishkina, Svitlana V., Ivan A. Isaiev, Viktoriya V. Urzhuntseva, and Vitalii A. Palchykov. "The formation of the salt and neutral molecule cocrystal from equimolar solution of heliamine and bicyclo[2.2.1]hept-5-ene-endo-2,3-dicarboxylic acid." Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials 75, no. 2 (2019): 192–200. http://dx.doi.org/10.1107/s205252061900115x.

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The possible interaction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline (heliamine) with bicyclo[2.2.1]hept-5-ene-endo-2,3-dicarboxylic acid anhydride has been studied. Instead of the reaction with heliamine, the acid anhydride was hydrolyzed into the appropriate dicarboxylic acid. An equimolar mixture of unreacted heliamine and in-situ-generated dicarboxylic acid crystallized in space group P21/c. The comprehensive study of the obtained crystals shows that the peculiarities of the crystallization process lead to the formation of the salt-cocrystal structure where the dianion interacts simult

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22

Palvanov, Narbek Sapaevich, and Mukhiddin Sultanovich Mekhmanov. "Electrometric Determination Of Binary Mixtures In Food." American Journal of Applied sciences 03, no. 06 (2021): 8–13. http://dx.doi.org/10.37547/tajas/volume03issue06-02.

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In this paper, the possibility of acid-base titration of binary mixtures of dicarboxylic acids in mixed and non-aqueous solutions is investigated. The possibility of titrimetric potentiometric determination of binary mixtures of dicarboxylic acids is shown.

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23

Guerriero, P., U. Casellato, S. Sitran, P. A. Vigato, and R. Graziani. "Lanthanide complexes with pyridine-2,6-dicarboxylic and thiophene-2,5-dicarboxylic acids." Inorganica Chimica Acta 139, no. 1-2 (1987): 67–68. http://dx.doi.org/10.1016/s0020-1693(00)84038-4.

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24

Chen, Chia-Jou, Chia-Ling Chen, Yu-Hsiang Liu, et al. "Coordination Polymers Constructed from Semi-Rigid N,N′-Bis(3-pyridyl)terephthalamide and Dicarboxylic Acids: Effect of Ligand Isomerism, Flexibility, and Identity." Chemistry 3, no. 1 (2020): 1–12. http://dx.doi.org/10.3390/chemistry3010001.

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Reactions of the semi-rigid N,N′-bis(3-pyridyl)terephthalamide (L) with divalent metal salts in the presence of dicarboxylic acids afforded [Cd(L)0.5(1,2-BDC)(H2O)]n (1,2-H2BDC = benzene-1,2-dicarboxylic acid), 1, {[Cd(L)1.5(1,3-BDC)(H2O)]·5H2O}n (1,3-H2BDC = benzene-1,3-dicarboxylic acid), 2a, {[Cd(1,3-BDC)(H2O)3]·2H2O}n, 2b, {[Cd(L)0.5(1,4-BDC)(H2O)2]·H2O}n (1,4-H2BDC = benzene-1,4-dicarboxylic acid), 3, and [Cu(L)0.5(5-tert-IPA)]n (5-tert-IPA = 5-tert-butylbenzene-1,3-dicarboxylic acid), 4, which have been structurally characterized by single crystal X-ray diffraction. Complexes 1 and 3 are

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25

Soonsin, V., A. A. Zardini, C. Marcolli, A. Zuend, and U. K. Krieger. "The vapor pressures and activities of dicarboxylic acids reconsidered: the impact of the physical state of the aerosol." Atmospheric Chemistry and Physics Discussions 10, no. 8 (2010): 20515–58. http://dx.doi.org/10.5194/acpd-10-20515-2010.

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Abstract. We present vapor pressure data of the C2 to C5 dicarboxylic acids deduced from measured evaporation rates of single levitated particles as both, aqueous droplets and solid crystals. The data of aqueous solution particles over a wide concentration range allow us to directly calculate activities of the dicarboxylic acids and comparison of these activities with parameterizations reported in the literature. The data of the pure liquid state acids, i.e. the dicarboxylic acids in their supercooled melt state, exhibit no even-odd alternation in vapor pressure, while the acids in the solid f

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26

Soonsin, V., A. A. Zardini, C. Marcolli, A. Zuend, and U. K. Krieger. "The vapor pressures and activities of dicarboxylic acids reconsidered: the impact of the physical state of the aerosol." Atmospheric Chemistry and Physics 10, no. 23 (2010): 11753–67. http://dx.doi.org/10.5194/acp-10-11753-2010.

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Abstract. We present vapor pressure data of the C2 to C5 dicarboxylic acids deduced from measured evaporation rates of single levitated particles as both, aqueous droplets and solid crystals. The data of aqueous solution particles over a wide concentration range allow us to directly calculate activities of the dicarboxylic acids and comparison of these activities with parameterizations reported in the literature. The data of the pure liquid state acids, i.e. the dicarboxylic acids in their supercooled melt state, exhibit no even-odd alternation in vapor pressure, while the acids in the solid f

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27

Thathong, Yuranan, Kittiya Wongkhan, and Rukkiat Jitchati. "Two Ruthenium Complexes with Phenanthroline Ligand for Dye-Sensitized Solar Cells." Advanced Materials Research 651 (January 2013): 115–19. http://dx.doi.org/10.4028/www.scientific.net/amr.651.115.

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We report the synthetic route of two ruthenium dye-sensitizers; namely, Ru(4,4-dicarboxylic-2,2-bipyridine)(1,10-phenanthroline)(NCS)2 (6) and Ru(4,4-dicarboxylic-2,2-bipyridine)(1,10-phenanthroline-5-carboxylic acid)(NCS)2 (7), which both complexes were characterized by 1H NMR, 13C NMR and UV-Vis spectroscopic techniques.

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28

Premkumar, Thathan, Subbiah Govindarajan, Wojciech Starosta, and Janusz Leciejewicz. "Pyrazine-2,3-dicarboxylic acid." Acta Crystallographica Section E Structure Reports Online 60, no. 8 (2004): o1305—o1306. http://dx.doi.org/10.1107/s1600536804016216.

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29

Deng, Shao-Hua, Jun Zhao, Yi-Qiang Mu, Cai Li, and Hui-Min Liu. "Biphenyl-3,3′-dicarboxylic acid." Acta Crystallographica Section E Structure Reports Online 67, no. 5 (2011): o1221. http://dx.doi.org/10.1107/s1600536811014334.

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30

Fitzgerald, L. J., and R. E. Gerkin. "Anthracene-1,8-dicarboxylic Acid." Acta Crystallographica Section C Crystal Structure Communications 52, no. 7 (1996): 1838–41. http://dx.doi.org/10.1107/s0108270196002703.

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31

Johnson, David W. "Synthesis of dicarboxylic acylcarnitines." Chemistry and Physics of Lipids 129, no. 2 (2004): 161–71. http://dx.doi.org/10.1016/j.chemphyslip.2004.01.001.

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32

Fitzgerald, Lawrence J., Roger E. Gerkin, and Gordon D. Renkes. "Infrared spectra of naphthalene-1,8-dicarboxylic acid and naphthalene-1,8-dicarboxylic anhydride." Vibrational Spectroscopy 2, no. 4 (1991): 269–71. http://dx.doi.org/10.1016/0924-2031(91)85036-m.

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33

Lin, Hong-Liang, Tieh-Kang Wu, Yu-Ting Huang, and Shan-Yang Lin. "Studies on Cocrystal Formation of Metaxalone with Short-chain Dicarboxylic Acids." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C658. http://dx.doi.org/10.1107/s2053273314093413.

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A possible cocrystal formation between metaxalone and short-chain dicarboxylic acids (HOOC-(CH2)n-COOH, n=0-3) was quickly investigated using a solvent-assisted grinding approach. Differential scanning calorimetry (DSC), Fourier transform infrared (FTIR) microspectroscopy, and powder X-ray diffraction (PXRD) were used to verify the cocrystal formation between metaxalone and each dicarboxylic acid. A solvent evaporation method was used to prepare the standard cocrystal. The cocrystal formation was also estimated by using a one-step simultaneous DSC-FTIR microspectroscopy. The present study indi

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34

Melicherčík, Milan, Marta Mrákavová, Arpád Nagy, Anna Olexová, and Ľudovít Treindl. "Design of Transition-Metal Oscillators Based on the Reduction of Permanganate Ions by Keto Dicarboxylic Acids." Collection of Czechoslovak Chemical Communications 60, no. 5 (1995): 781–87. http://dx.doi.org/10.1135/cccc19950781.

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Permanganate chemical oscillators with some keto dicarboxylic acids in the presence of phosphoric acid in a continuously stirred tank reactor (CSTR) are described in terms of the phase diagrams in the [ketomalonic acid]o-ko, [oxalacetic acid]o-ko, and [α-ketoglutaric acid]o-ko planes, and in the [H3PO4]o-ko , [MnO4-]o-ko , temperature-ko planes. The results show that an optimum degree of stabilization of the Mn(IV) colloid, which may serve as a reservoir of solvated Mn(IV) ions participating in the elementary reaction steps, is a prerequisite for the oscillations in the MnO4--keto dicarboxylic

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35

Çapan, İrfan, and Süleyman Servi. "Synthesis of New C2-Symmetric Chiral Benzimidazole Derivatives Having Norbornene/Dibenzobarrelene Skeletons." Letters in Organic Chemistry 17, no. 10 (2020): 801–5. http://dx.doi.org/10.2174/1570178616666190731105327.

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Racemic dicarboxylic acids were synthesized from the Diels-Alder cycloaddition reactions which formed the dibenzobarrelene and norbornene skeletons. The pure enantiomers of these compounds were obtained using brucine as the chiral auxiliary. Novel C2-symmetric chiral benzimidazole derivatives were synthesized from the reaction of the diaminobenzene and enantiomeric dicarboxylic acids in the presence of boric acid.

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36

Cho, Seung-Hwan, Ju-Hyun Song, Do-Hun Lee, et al. "Synthesis and Reaction of 1,5,3,7-Diazadiphosphocine-1,5-Dicarboxylic Acids." Journal of Life Science 17, no. 7 (2007): 910–14. http://dx.doi.org/10.5352/jls.2007.17.7.910.

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37

Kiuchi, Fumiyuki. "Saponin constituents of Achyranthes root." Journal of Natural Medicines 76, no. 2 (2022): 343–51. http://dx.doi.org/10.1007/s11418-021-01591-1.

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AbstractAchyranthes root is a crude drug used as diuretic, tonic and remedy for blood stasis. Characteristic oleanolic acid saponins with a dicarboxylic acid moiety have been isolated as one of the representative constituents of this crude drug. This review focuses on the triterpene saponin constituents, especially those with a characteristic dicarboxylic acid moiety, of A. bidentata and A. fauriei. Several groups isolated the saponins and different names were given to one compound in some cases. The names of the compounds are sorted out and the stereochemistry of the dicarboxylic acid moietie

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38

Allan, RD, RK Duke, TW Hambley, et al. "Synthesis of Unsaturated Analogues of Glutamic Acid: Amination of Trianions From Unsaturated Dicarboxylic Acids With Chloramine." Australian Journal of Chemistry 49, no. 7 (1996): 785. http://dx.doi.org/10.1071/ch9960785.

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Trianions can be formed from dicarboxylic acids which contain a β,γ -double bond, and amination with chloramine yields β,γ-unsaturated α-amino acids. This methodology provides a convenient synthesis of amino acids that are inaccessible by other routes. (Z)-3-Phenylthiopent-2-enedioic acid and all four stable unsaturated analogues of the conformationally restricted glutamate analogue 1-aminocyclopentane-1,3-dicarboxylic acid have been synthesized to demonstrate the applicability of the method. The structure of one of the amino acid products, (�)-cis-1-aminocyclopent-4-ene-1,3-dicarboxylic acid

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39

Vandana, Singh, and Baqi Abdul. "Synthesis of some novel porphyrins." Journal of Indian Chemical Society Vol. 79, Nov 2002 (2002): 908–10. https://doi.org/10.5281/zenodo.5847976.

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Department of Chemistry, University of Allahabad, Allahabad-211 002, India E-mail: singhvandanasingh@rediffmail.com <em>Manuscript received 11 September 2001, revised 17 May 2002, accepted 21 June 2002</em> 2,3,6,7-Tetra(2-methoxycarbonylethyl)-1,4,5,8-tetramethylporphin [coproporphyrin II, tetra methyl ester] (9) and 2,3-di(2- methoxyearbonylethyl)-6,7-dimethoxycarbonylmethyi-1,4,5,8-tetramethylporphin [a new synthetic coproporphyrin] (10) were synthesized by condensing 3,3'-di(2-ethoxycarbonylethyl)-4,4'-dimethyl-2,2'-dipyrrylmethane-5,5'-dicarboxylie acid (5) with 3,3&#

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40

Zhang, Shi-Jie, Yi-Chun Ma, Wei Zhou, Guo-Wu Rao, Liang-Liang Chen, and Wei-Xiao Hu. "Synthesis of esters and amides of 1,4-dihydro-1,2,4,5-tetrazine-3,6-dicarboxylic acid." Journal of Chemical Research 2009, no. 10 (2009): 645–48. http://dx.doi.org/10.3184/030823409x12532880130972.

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Alkyl esters and alkyl amides of 1,4-dihydro-1,2,4,5-tetrazine-3,6-dicarboxylic acid were synthesised and characterised by IR, 1H NMR, EI-MS and elemental analysis. The structure of 1,4-dihydro-1,2,4,5-tetrazine-3,6-dicarboxylic was confirmed by X-ray diffraction analysis. Some selected compounds were evaluated against P-388 and A-549 cancer cell lines, but showed poor inhibitory activities.

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41

Guoliang, G. U., and L. U. Ming. "Novel and Efficient Procedure for the Preparation of Two Pyridine Dicarboxylic Acid Derivatives." E-Journal of Chemistry 8, no. 1 (2011): 449–52. http://dx.doi.org/10.1155/2011/120730.

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New strategies for the synthesis of two pyridine dicarboxylic acid derivatives namely; 4-(2-(2,6-dicarboxypyridin-4-yl)vinyl)pyridine-2,6-dicarboxylic acid and 2,6-bis(2-(2,6–dicarboxy-pyridin-4-yl)vinyl)pyridine have been described. New oxidant used is a good example of green chemistry technology and the synthesis procedure harvest a high-purity product at a high yield.

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42

TRACEY, BERYL M., K. N. CHENG, and RONALD A. CHALMERS. "Mass spectrometric identification of dicarboxylic acid glucuronide esters in patients with dicarboxylic aciduria." Biochemical Society Transactions 16, no. 5 (1988): 744–45. http://dx.doi.org/10.1042/bst0160744.

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Hildebrand, U., K. Taraz, and H. Budzikiewicz. "6-(Hydroxythio) carbonyIpyridin-2-carbonsäure und Pyridin-2-carbon- säure-6-monothiocarbonsäure als biosynthetische Zwischenstufen bei der Bildung von Pyridin-2,6-di(monothiocarbonsäure) aus Pyridin-2,6- dicarbonsäure [1] / 6-(Hydroxythio)carbonylpyridine-2-carboxylic Acid and Pyridine-2-carboxylic Acid-6- monothiocarboxylic Acid as Interm ediates in the Biosynthesis of Pyridine-2,6-di(monothiocarboxylic Acid) from Pyridine-2,6-dicarboxylic Acid [1]." Zeitschrift für Naturforschung C 41, no. 7-8 (1986): 691–94. http://dx.doi.org/10.1515/znc-1986-7-805.

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Abstract It is shown by feeding experiments with [3-2H]pyridine-2,6 -dicarboxylic acid that 6 -(hydroxythio)carbonylpyridine-2-carboxylic acid and pyridine-2 -carboxylic acid-6-m onothiocarboxylic acid are intermediates in the biosynthesis of pyridine-2,6 -di(monothiocarboxylic acid) from pyridine-2,6 -dicarboxylic acid produced by Pseudomonas putida. Thus the series of biosynthetic steps - COOH → - CO - SOH → COSH has been demonstrated for the first time.

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44

Owalude, Samson O., Oyeyemi A. Adeyoju, Damilola Y. Adegbola, Muhammed O. Shittu, Olusola O. James, and Adedibu C. Tella. "Synthesis and characterization of a tetranuclear Cu(II) coordination polymer containing pyridine-2,6-dicarboxylic acid and 4-amidinopyridine co-ligand." Dutse Journal of Pure and Applied Sciences 8, no. 1b (2022): 27–32. http://dx.doi.org/10.4314/dujopas.v8i1b.4.

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This research demonstrates the preparation of a new coordination polymer, {[Cu4(H2pydc)2(H1apy)(H2O)2DMF].DMF}n, (H2pydc = pyridine-2,6-dicarboxylic acid, H1apy = 4-amidinopyridine) under solvothermal condition by the self-assembly of pyridine-2,6-dicarboxylic acid, 4-midinopyridene and copper(II) acetate. The compound was characterized by elemental analysis and infrared spectroscopic technique. The analysis indicated that the 4-amidinopyridine coordinated to the copper ions through the terminal nitrogen in a monodentate fashion while the pyridine-2,6-dicarboxylic acids coordinated through the

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45

Lynch, DE, G. Smith, KA Byriel, CHL Kennard, and AK Whittaker. "Molecular Cocrystals of Carboxylic Acids. XIV. The Crystal Structures of the Adducts of Pyrazine-2,3-dicarboxylic Acid With 4-Aminobenzoic Acid, 3-Hydroxypyridine and 3-Amino-1,2,4-triazole." Australian Journal of Chemistry 47, no. 2 (1994): 309. http://dx.doi.org/10.1071/ch9940309.

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The 1:1 molecular adducts of pyrazine-2,3-dicarboxylic acid with 4-aminobenzoic acid, [(C6H3N2O4)-(C7H8NO2)+], 3-hydroxypyridine, [(C6H4N2O4) (C5H5NO)], and 3-amino-1,2,4-triazole, [(C6H3N2O4)-(C2H5N4)+] have been prepared, and their structures determined by X-ray diffraction methods. All structures involve intra- and inter-molecular hydrogen-bonding interactions. The 1:2 complex of pyrazine-2,3-dicarboxylic acid with triphenylphosphine oxide has also been prepared, and characterized by using spectroscopic methods.

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46

Skoryna, D. Yu, O. Yu Voskoboinik, and S. I. Kovalenko. "Reactions of 1,4-NCCN-, 1,4-NNCN- and 1,5-NCCCN-binucleophiles with dicarboxylic acids cyclic anhydrides as a method of heterocyclic compounds synthesis (a review)." Voprosy Khimii i Khimicheskoi Tekhnologii, no. 3 (June 2023): 29–53. http://dx.doi.org/10.32434/0321-4095-2023-148-3-29-53.

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Critical analysis of published information related to the features of reaction of 1,4-NCCN-, 1,4-NNCN and 1,5-NCCCN-binucleophiles with cyclic anhydrides of dicarboxylic acids has been presented in the review. It has been shown that the reaction of named anhydrides with 1,4-NCCN-binucleophiles leads to the formation of the imidazole fragment that contains carboxyl-containing moiety. It has been shown that benzimidazole derivatives are among the most studied products of reaction between 1,4-NCCN- and cyclic anhydrides of dicarboxylic acids due to the high availability of initial compounds. The

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47

Sugiura, Yuki, Yasuko Saito, Etsuko Yamada, and Masanori Horie. "Fabrication of Dicarboxylic-Acid- and Silica-Substituted Octacalcium Phosphate Blocks with Stronger Mechanical Strength." Ceramics 7, no. 2 (2024): 796–806. http://dx.doi.org/10.3390/ceramics7020052.

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Octacalcium phosphate (OCP) is an attractive base material to combine into components developed for medical purposes, especially those used in bone replacement procedures, not only because of its excellent biocompatibility but also because of its ability to intercalate with multiple types of molecular layers such as silica, dicarboxylic acid, and various cations. On the other hand, there are no examples of simultaneous substituting for several different compounds on OCPs. Therefore, in this study, the physical and mechanical strength (DTS: diametral tensile strength) of OCPs substituted with b

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48

Fiume, Monice M., HBart eldreth, Wilma F. Bergfeld, et al. "Final Report of the Cosmetic Ingredient Review Expert Panel on the Safety Assessment of Dicarboxylic Acids, Salts, and Esters." International Journal of Toxicology 31, no. 4_suppl (2012): 5S—76S. http://dx.doi.org/10.1177/1091581812447203.

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The CIR Expert Panel assessed the safety of dicarboxylic acids and their salts and esters as used in cosmetics. Most dicarboxylic acids function in cosmetics as pH adjusters or fragrance ingredients, but the functions of most of the salts in cosmetics are not reported. Some of the esters function as skin conditioning or fragrance ingredients, plasticizers, solvents, or emollients. The Expert Panel noted gaps in the available safety data for some of the dicarboxylic acid and their salts and esters in this safety assessment. The available data on many of the ingredients are sufficient, however,

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49

Tichý, Miloš, Jana Holanová, Ivo Starý, Irena G. Stará, and Jiří Závada. "Axially Chiral Selectors of C2 Symmetry Bound to Silica: Synthesis and HPLC-Evaluation." Collection of Czechoslovak Chemical Communications 60, no. 4 (1995): 645–58. http://dx.doi.org/10.1135/cccc19950645.

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Axially chiral biaryl stationary phases (CSPs) of C2 symmetry bound to 3-aminopropyl silica both by ionic and covalent bond were prepared. The separation effectivity of the CSPs so obtained was investigated using 2-acylamino alcohols and biaryl derivatives as analytes. Whereas ionically bound phases derived from biphenyl-2,2'-dicarboxylic or 2,2'-bipyridine-3,3'-dicarboxylic acids (CSP 1, 2, 3 and 4) generally exhibited good resolving performance for 2-acylamino alcohols, they were ineffective for biaryl derivatives. On the other hand, covalent CSPs showed poor selector properties with acylami

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50

Song, J. H., S. M. Bae, S. K. Cho, J. H. Cho, and D. I. Jung. "A Study on N-Substituted Nortropinone Synthesis using Acetone Equivalents." Asian Journal of Chemistry 32, no. 5 (2020): 1145–50. http://dx.doi.org/10.14233/ajchem.2020.22537.

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Robinson′s synthesis has long been a classic in organic chemistry due to its simplicity and impact in the industry. Various modifications have been made to improve the system. Among them, replacing acetone with more acidic chemical equivalents such as calcium dicarboxylic acid or ethyl dicarboxylic acetone improved the yield. In line with this trend, our group previously reported the synthesis of mono- and di-N-substituted tropinone derivatives from the one-pot reaction of 2,5-dimethoxy tetrahydrofuran and various amines with acetonedicarboxylic acid in the presence of HCl and water at room te

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