Log in

Relevant bibliographies by topics / Dichaete

Contents

Journal articles
Dissertations / Theses
Books
Conference papers

Academic literature on the topic 'Dichaete'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Dichaete.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Dichaete"

1

Soriano, N. S., and S. Russell. "The Drosophila SOX-domain protein Dichaete is required for the development of the central nervous system midline." Development 125, no. 20 (October 15, 1998): 3989–96. http://dx.doi.org/10.1242/dev.125.20.3989.

Full text

Abstract:

SOX-domain proteins are a class of developmentally important transcriptional regulators related to the mammalian testis determining factor SRY. In common with other SOX-domain genes, the Drosophila Dichaete gene has a dynamic expression profile in the developing central nervous system, including cells of the ventral midline. We find defects in the differentiation of midline glia and concomitant axonal defects in Dichaete mutants that are rescued by driving Dichaete expression in the midline. Since Dichaete is required for the correct specification or differentiation of midline glia, we have used the ventral midline as a model system to study SOX gene function in vivo and demonstrate a genetic interaction between Dichaete and the POU domain gene ventral veinless. In mammals, a protein related to Dichaete, SOX2, also interacts with POU transcription factors. The midline phenotypes of Dichaete mutations are rescued by expression of mouse SOX2. Our data suggest that SOX gene structure, function and interactions have been conserved during evolution.

APA, Harvard, Vancouver, ISO, and other styles

2

Zhao, Guoyan, and James B. Skeath. "The Sox-domain containing geneDichaete/fish-hookacts in concert withvndandindto regulate cell fate in theDrosophilaneuroectoderm." Development 129, no. 5 (March 1, 2002): 1165–74. http://dx.doi.org/10.1242/dev.129.5.1165.

Full text

Abstract:

In the Drosophila embryonic central nervous system, neural stem cells, called neuroblasts, acquire fates in a position-specific manner. Recent work has identified a set of genes that functions along the dorsoventral axis to enable neuroblasts that develop in different dorsoventral domains to acquire distinct fates. These genes include the evolutionarily conserved transcription factors ventral nerve cord defective and intermediate neuroblasts defective, as well as the Drosophila EGF receptor. We show that the Sox-domain-containing gene Dichaete/fish-hook also plays a crucial role to pattern the neuroectoderm along the DV axis. Dichaete is expressed in the medial and intermediate columns of the neuroectoderm, and mutant analysis indicates that Dichaete regulates cell fate and neuroblast formation in these domains. Molecular epistasis tests, double mutant analysis and dosage-sensitive interactions demonstrate that during these processes, Dichaete functions in parallel with ventral nerve cord defective and intermediate neuroblasts defective, and downstream of EGF receptor signaling to mediate its effect on development. These results identify Dichaete as an important regulator of dorsoventral pattern in the neuroectoderm, and indicate that Dichaete acts in concert with ventral nerve cord defective and intermediate neuroblasts defective to regulate pattern and cell fate in the neuroectoderm.

APA, Harvard, Vancouver, ISO, and other styles

3

Russell, S. R., N. Sanchez-Soriano, C. R. Wright, and M. Ashburner. "The Dichaete gene of Drosophila melanogaster encodes a SOX-domain protein required for embryonic segmentation." Development 122, no. 11 (November 1, 1996): 3669–76. http://dx.doi.org/10.1242/dev.122.11.3669.

Full text

Abstract:

We have cloned and characterised a member of the High Mobility Group superfamily of genes from Drosophila, Sox70D, which is closely related to the mammalian testis determining gene SRY. Sox70D corresponds to the dominant wing mutation Dichaete. Homozygous deletions of the Sox70D gene and recessive lethal Dichaete alleles have a variable embryonic segmentation phenotype. Dichaete is expressed in early embryos in a dynamic pattern reminiscent of gap and pair-rule genes and is required for the appropriate expression of the primary pair-rule genes even skipped, hairy and runt. The molecular nature of Dichaete and its expression pattern during early embryogenesis suggest that the gene plays a key role in early development; the variability in both the segmentation phenotype and the effects on pair-rule gene expression suggests that this role is to support the transcriptional regulation of key developmental genes rather than directly regulate any one of them.

APA, Harvard, Vancouver, ISO, and other styles

4

Overton, Paul M., Lisa A. Meadows, Joachim Urban, and Steven Russell. "Evidence for differential and redundant function of the Sox genesDichaeteandSoxNduring CNS development inDrosophila." Development 129, no. 18 (September 15, 2002): 4219–28. http://dx.doi.org/10.1242/dev.129.18.4219.

Full text

Abstract:

Group B Sox-domain proteins encompass a class of conserved DNA-binding proteins expressed from the earliest stages of metazoan CNS development. In all higher organisms studied to date, related Group B Sox proteins are co-expressed in the developing CNS; in vertebrates there are three (Sox1, Sox2 and Sox3) and in Drosophila there are two (SoxNeuro and Dichaete). It has been suggested there may be a degree of functional redundancy in Sox function during CNS development. We describe the CNS phenotype of a null mutation in the Drosophila SoxNeuro gene and provide the first direct evidence for both redundant and differential Sox function during CNS development in Drosophila. In the lateral neuroectoderm, where SoxNeuro is uniquely expressed, SoxNeuro mutants show a loss or reduction of achaete expression as well as a loss of many correctly specified lateral neuroblasts. By contrast, in the medial neuroectoderm, where the expression of SoxNeuro and Dichaete overlaps, the phenotypes of both single mutants are mild. In accordance with an at least partially redundant function in that region, SoxNeuro/Dichaete double mutant embryos show a severe neural hypoplasia throughout the central nervous system, as well as a dramatic loss of achaete expressing proneural clusters and medially derived neuroblasts. However, the finding that Dichaete and SoxN exhibit opposite effects on achaete expression within the intermediate neuroectoderm demonstrates that each protein also has region-specific unique functions during early CNS development in the Drosophila embryo.

APA, Harvard, Vancouver, ISO, and other styles

5

Aleksic, Jelena, Enrico Ferrero, Bettina Fischer, Shih Shen, and Steven Russell. "The role of Dichaete in transcriptional regulation during Drosophila embryonic development." BMC Genomics 14, no. 1 (2013): 861. http://dx.doi.org/10.1186/1471-2164-14-861.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Mutsuddi, Mousumi, Ashim Mukherjee, Baohe Shen, James L. Manley, and John R. Nambu. "Drosophila Pelle phosphorylates Dichaete protein andinfluences its subcellular distribution in developing oocytes." International Journal of Developmental Biology 54, no. 8-9 (2010): 1309–15. http://dx.doi.org/10.1387/ijdb.092991mm.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Mukherjee, Ashim, Krishna V. Melnattur, Mao Zhang, and John R. Nambu. "Maternal expression and function of the Drosophila sox gene Dichaete during oogenesis." Developmental Dynamics 235, no. 10 (August 7, 2006): 2828–35. http://dx.doi.org/10.1002/dvdy.20904.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Russell, S. "The Drosophila dominant wing mutation Dichaete results from ectopic expression of a Sox-domain gene." Molecular and General Genetics MGG 263, no. 4 (May 2000): 690–701. http://dx.doi.org/10.1007/s004380051218.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Sánchez-Soriano, Natalia, and Steven Russell. "Regulatory Mutations of the Drosophila Sox Gene Dichaete Reveal New Functions in Embryonic Brain and Hindgut Development." Developmental Biology 220, no. 2 (April 2000): 307–21. http://dx.doi.org/10.1006/dbio.2000.9648.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Ferrero, Enrico, Bettina Fischer, and Steven Russell. "SoxNeuro orchestrates central nervous system specification and differentiation in Drosophila and is only partially redundant with Dichaete." Genome Biology 15, no. 5 (2014): R74. http://dx.doi.org/10.1186/gb-2014-15-5-r74.

Full text

APA, Harvard, Vancouver, ISO, and other styles

More sources

Dissertations / Theses on the topic "Dichaete"

1

Shen, Shih-Pei. "Characterisation of Dichaete functions and targets during Drosophila embryonic development." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612743.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Aleksic, Jelena. "The role of Dichaete in transcriptional regulation during Drosophila embryonic development." Thesis, University of Cambridge, 2012. https://www.repository.cam.ac.uk/handle/1810/243616.

Full text

Abstract:

Sox domain genes encode a family of developmentally important transcription factors conserved throughout the Metazoa. The subgroup B, which includes the mammalian Sox1, 2 and 3 proteins and their Drosophila counterparts Dichaete and SoxNeuro, are particularly important for the development of the nervous system where they appear to play conserved roles in neuronal specification and differentiation. Despite years of detailed study we still have a relatively poor idea of how Sox proteins function on a genome wide scale and the aim of my PhD work was to explore this aspect using the fly group B protein, Dichaete. A number of studies have shown that Dichaete performs a variety of critical functions during development and a few individual regulatory targets have been defined, however, at the start of my work no genome-wide data on Dichaete action were available. While such data emerged from large scale initiatives during my work, a systematic analysis of Dichaete action was lacking. Here I describe the first detailed genomic analysis of Dichaete activity, with a particular focus on three areas: finding the locations of Dichaete binding in the genome, a prediction of potential Dichaete cofactors and an analysis of Dichaete effects on gene expression. To address the issue of where Dichaete binds in the genome, I generated whole genome DamID data for embryos and followed this with a detailed comparative analysis, combining my data with three newly published ChIP-chip datasets. The combined studies identify thousands of binding regions, mostly in the vicinity of developmentally important genes. The binding profiles were found to be consistent with Dichaete acting on enhancer regions and also suggest a role in facilitating RNA Polymerase II pausing. The analysis also identified a Dichaete binding motif closely matching that found with in vitro studies. By combined ChIP and DamID datasets I generated a very high confidence core Dichaete binding dataset, which should be of considerable use in future studies. To identify potential Dichaete cofactors, I compiled the available embryonic transcription factor binding data from the Berkeley Drosophila Transcription Network and mod- ENCODE projects, and identified significant overlaps with the core Dichaete binding data. A number of the proteins highlighted in this analysis have known roles during neuroblast development, including Hunchback and Krüppel, transcription factors involved in temporal specification of neuroblast division, and Prospero, which plays a key role in neuroblast differentiation. The analysis suggests that Dichaete has a role during early neuroblast divisions, where it likely interacts with Hb and Kr to maintain neuroblast pluripotency. This is a role consistent with previous studies in Drosophila larval neuroblasts and is analogous to neural functions of Sox2 in mammals. My analysis suggests that Dichaete acts on the same target genes as Prospero but in an antagonistic role, with Dichaete preventing stem cell differentiation and Prospero promoting it. To examine the effects of Dichaete on gene expression, a number of microarray transcript profiling studies were performed, including a global study with Dichaete null mutants, and tissue specific studies in the CNS midline and neuroblasts via the use of dominant negative constructs. Whole transcriptome expression profiling data was combined with the binding data to establish a set of high confidence potential Dichaete targets, both for specific tissues and more globally during neurogenesis. Specific high confidence targets were found, including bancal during nervous system development. It was also concluded that Dichaete is likely to prevent cell cycle exit by repressing the apoptosis genes grim, hid and reaper, as well as the differentiation genes prospero and miranda. An extensive list of potential Dichaete direct targets was generated and can be used for validation and future research.

APA, Harvard, Vancouver, ISO, and other styles

3

Ferrero, Enrico. "The role of SoxNeuro during Drosophila development and its relationship with Dichaete." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708075.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Sanchez, Soriano Natalia. "Analysis of the in vivo function of the Drosophila Sox gene Dichaete." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624526.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Maher, Joshua Paul. "Investigating the functional and evolutionary significance of Group B Sox genes in arthropods." Thesis, University of Cambridge, 2017. https://www.repository.cam.ac.uk/handle/1810/269702.

Full text

Abstract:

Group B Sox genes play a critical developmental role in both vertebrates and insects. Within the model species Drosophila melanogaster, two SoxB genes, Dichaete and SoxNeuro, have been shown to act as ‘master regulators’ in the early development of the central nervous system. SoxB genes have only been characterised in a handful of arthropod species thus far, with most work to date focusing on drosophilids. The purpose of this investigation was twofold. First, I set out to resolve the phylogenetic origins of arthropod SoxB genes, as mutually exclusive models explaining their emergence are still contested. I have identified and annotated the SoxB of several invertebrate taxa. In total, my investigation includes 24 different metazoan taxa, and represents the largest investigation of arthropod SoxB phylogeny to date. In light of this research, I have proposed a new model of SoxB evolution which resolves the conflicting elements of the two primary competing models. Second, to study the evolution of SoxB in terms of functional conservation/divergence, I selected the emerging model organism Tribolium castaneum to draw a comparative analysis with Drosophila melanogaster. I first began by characterising the spatiotemporal expression patterns of SoxNeuro mRNA in early Tribolium embryos using whole mount in situ hybridisation, and examined published Dichaete expression patterns in the context of central nervous system development in T. castaneum. Using these data, I draw a comparison to the expression profiles of Dichaete and SoxNeuro orthologues in Drosophila melanogaster and other species. I have found that both Dichaete and SoxNeuro expression patterns in the developing central nervous system are remarkably well-conserved across species. I also attempted to characterise genome-wide binding for both Dichaete and SoxNeuro proteins in Tribolium in what would have represented the first genomic investigation of its kind in this emerging species. Using a tethered DNA adenine methyltransferase (Dam) enzyme for both SoxNeuro and Dichaete, I hoped to characterise the genomic loci with which each protein interacts within the beetle genome (a technique known as DamID). Unfortunately, these last set of experiments have proved unsuccessful, despite several attempts which have made use of different promoters, different DNA enrichment methodologies, and tackling unforeseen DNA contamination issues. Nevertheless, the troubleshooting experiments that I have carried out will pave the way for further genomic experiments in Tribolium, easing the establishment of genomic research in this emerging organism.

APA, Harvard, Vancouver, ISO, and other styles

6

Anastaze, Marie. "Parque Emergencia de la Solidaridad : redefinir la emergencia en Chile ¿cómo habitar un país que vibra?" Tesis, Universidad de Chile, 2017. http://repositorio.uchile.cl/handle/2250/168395.

Full text

Abstract:

Memoria para optar al título de Arquitecta
Nuestro planeta está animado por dinámicas telúricas que se manifiestan en temblores de diversas magnitudes, terremotos que llegan a dañar el hábitat humano y pueden reconfigurar la geografía existente, y tsunamis que arrasan con los asentamientos costeros. En Chile, estos eventos naturales participan en la construcción de una manera particular de habitar el territorio. Durante los pocos minutos que dura un terremoto, las pocas horas que se demoran las olas del mar en calmar su agitación, por un lado, los habitantes de este país entran en sintonía, dejando emerger emociones de solidaridad, y por otro lado, se pone en marcha un proceso de “situación de emergencia”. La “situación de emergencia” debida a estos dos eventos naturales se inicia con una ruptura del cotidiano, para dejar espacio a un tiempo post-evento antes de que se abran las etapas de vuelta al cotidiano. Aquella instancia de “tiempo post-evento” pone en crisis la intimidad de los chilenos y sus bienes materiales (casa, pertenencias). Los sentimientos de necesidad de seguridad, de sociabilización y de solidaridad que mueven los habitantes en este tiempo preciso consisten un capital social (llamado Sigma). Surge por ende la pregunta de ¿Cómo, desde la arquitectura, completamos y/o mejoramos el proceso existente? La arquitectura, desde un enfoque fenomenológico, tiene un rol trascendental en la medida en que marca la permanencia en el mundo físico de lo que nos escapa (el tiempo, la vejez, la muerte). El tiempo post evento mencionado no deja rastros de la vivencia de este empuje común chileno, que sin embargo, está condenado a reiterarse a la próxima descarga de energía de la Tierra. Se abre la oportunidad, con esta investigación, de dar cabida a este momento, de empeñarse en cultivar estos dos minutos, que ponen en relación los chilenos con ellos mismos, sus pares, su territorio y sus identidades. Posibilitar, con la arquitectura, que este momento se vuelva trascendental y recorra las etapas de vuelta al cotidiano hasta convertirse en un integrante de la vida local. Surge la idea de un “refugio Sigma” que esté presente en las diferentes escalas del territorio y desde la etapa de prevención, asegurando la continuidad espacio-temporal y fomentando la organización y participación local. El carácter impredecible de ambos fenómenos naturales y de sus magnitudes obliga a elegir un escenario real espacio-temporal (Dichato- 27 de febrero de 2010) para formular un escenario propuesto (Dichato- 27 de febrero 2010), recreando lo ocurrido e integrando las variables particulares del lugar de emplazamiento y sirviéndose de la experiencia pasada. En este sentido, Dichato está desarrollando un espacio seguro (Cesfam, Bomberos, estanques de agua) en los cerros cercanos, y, con aquello, iniciando un proceso de colonización del cerro en la ruta a Tomé. Con el fin de brindar un uso vecinal y cotidiano, se propone un “Parque de la Emergencia de la Solidaridad” para Dichato que será apoyo a las actividades residenciales vecinales (reunión de vecinos, eventos festivos, salidas familiares), organización local (agrupaciones), a las actividades del Cesfam (talleres para adultos mayores, embarazadas y para niños) y al turismo (camping).

APA, Harvard, Vancouver, ISO, and other styles

7

Hepp, Ahumada kimberly, and Ramírez Carolina Roco. "Dichato: las promesas y los costos de la reconstrucción chilena." Tesis, Universidad de Chile, 2013. http://repositorio.uchile.cl/handle/2250/145993.

Full text

Abstract:

Memoria para optar al título de periodista
Que la naturaleza no haya sido en vano Han pasado más de dos años desde el terremoto chileno de febrero de 2010 y aún continúan restos de casas desplomadas por las orillas de la playa de Dichato. El abandono a su población y la lentitud en la ejecución de la reconstrucción del balneario durante estos dos años han sido evidentes y esta realidad se repite en varias de las demás zonas afectadas por la catástrofe. Parece que la reconstrucción no fuera un tema de real importancia ni para el gobierno ni para los políticos de la oposición, no porque no se hayan realizado iniciativas que buscaran la reparación a los daños provocados por el terremoto, sino porque estas han carecido de profundidad y no solucionan los problemas de fondo y en muchos casos no pasaban de ser asistencialistas. La oposición en su rol como tal agotó sus energías más en descalificaciones y peleas públicas al gobierno y a la derecha chilena que a crear iniciativas que permitieran llenar los vacíos que estaba dejando el plan de reconstrucción. La reconstrucción y el terremoto se volvieron una pelea política, basada principalmente en desprestigiar al opositor. La concertación acusaba constantemente al ejecutivo de no cumplir con las promesas y los plazos. Mientras que la derecha no se cansaba en enrostrar a la oposición el rol de Michelle Bachelet en la catástrofe, olvidando que entre toda discusión se encontraban damnificados que urgían por una ayuda real y sobretodo digna. El gobierno no logró cuantificar la magnitud de la catástrofe y se apuró en entregar plazos para la reconstrucción, aseguró que durante el tercer invierno post terremoto ningún damnificado se encontraría en aldeas de emergencia, sin embargo al llegar a esta fecha debió reconocer que esta tarea era imposible. Asimismo, el Presidente aseguró durante el 2010 que el proceso tardaría dos años y medio. En febrero de 2012 afirmó que este duraría cuatro. Los damnificados comenzaron a desconfiar de la veracidad de los plazos, muchas construcciones no comenzaron en las fechas establecidas y fueron entregadas mucho después de lo presupuestado. Asimismo, las cifras oficiales de reconstrucción se contradecían con la realidad de los damnificados y con las cifras que entregaban otros organismos como fundaciones y ONG’s creando un ambiente de profunda desconfianza la que finalizó en protestas y represión policial en zonas como Dichato. Y ese fue uno de los grandes errores durante este proceso de reconstrucción en el balneario de Dichato, el gobierno subestimó la importancia de considerar a la ciudadanía al momento de crear un plan para levantar las zonas afectadas. Los damnificados se sintieron desplazados en las decisiones y consideraron que el gobierno no tomó en cuenta temas tan fundamentales como la historia y la identidad al momento de levantarse políticas de reconstrucción. De esta forma, tanto en el balneario de Dichato como en otras zonas devastadas el aire de desconfianza, de temor y de abandono aumentaba con cada día que la reconstrucción no avanzaba, que los plazos no se cumplían y que las promesas quedaban en eso…palabras. Hoy, al pasar más de dos años muchos damnificados continúan en aldeas de emergencia, insertados en el barro, la depresión y el hacinamiento con la desesperación de dejar de sentirse una prioridad. El hermoso balneario de Dichato dejó de ser la estrellita de los medios de comunicación, del morbo, para pasar al olvido, alumbrado escasos días por iniciativas como el “Viva Dichato”. Esta carencia de considerar a la ciudadanía en las decisiones sobre la reconstrucción es una consecuencia de la falta de un aprendizaje real tras el terremoto. Hasta hoy, dos años después del 27/F no se ha creado un organismo capacitado para reaccionar frente a catástrofes naturales, tan comunes en nuestro país, como se ha hecho en otros como Nueva Zelanda, Japón o Colombia. No se ha establecido un plan de acción que permita preparar y generar una cultura en la sociedad frente a una catástrofe de la magnitud del terremoto del 2010, no se han modificado las leyes de construcción y fiscalización de edificios, no se ha establecido de qué forma y en cuánto tiempo debe reaccionar el Estado frente a una catástrofe natural, ni cuáles serán las atribuciones de los privados. Hoy aseguramos la carencia de un plan de reconstrucción de fondo que asuma las necesidades de los damnificados con el respeto, transparencia y sobretodo la dignidad que merecen, pero también dudamos profundamente de la capacidad de nuestro país y de los futuro gobiernos de reaccionar frente a una nueva catástrofe del nivel de la del terremoto y posterior tsunami que afectó a Chile el 2010. Durante este terremoto, a diferencia de otros en nuestra historia pasada, los aprendizajes reflejados en políticas públicas, en leyes, en organismos han sido escasos. Los últimos mandatos no han tomado con conciencia real que Chile es un país que constantemente se enfrenta a este tipo de escenarios y que por lo tanto necesita estar a la altura, tanto las autoridades e instituciones como la población Si el gobierno de Sebastián Piñera como aquellos que vendrán no logran cambios reales en la forma en que en que se enfrentan las catástrofes, tanto Dichato como el resto de las zonas afectadas por este terremoto habrán sido víctimas en vano, como lo fueron Chaitén el 2008 y el Tocopilla el 2007, ya olvidados.

APA, Harvard, Vancouver, ISO, and other styles

8

Neubig, Kurt Maximillian. "Molecular systematics of the genus Dichaea (Zygopetalinae : Orchidaceae)." [Gainesville, Fla.] : University of Florida, 2005. http://purl.fcla.edu/fcla/etd/UFE0012820.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Arriagada, Sickinger Carolina. "Estrategias de planificación del manejo de las vulnerabilidades urbano sociales en el proceso de reconstrucción. Caso estudio localidad de Dichato, VIII región, Chile." Tesis, Universidad de Chile, 2016. http://repositorio.uchile.cl/handle/2250/140594.

Full text

Abstract:

Tesis para optar al grado de Magíster en Urbanismo
La presente investigación tiene como objetivo indagar cuáles fueron las estrategias de planificación del manejo de las vulnerabilidades urbano-sociales en el proceso de reconstrucción de la localidad de Dichato, Región del Bio Bio, afectada por el terremoto y tsunami del 27 de febrero del 2010, de aquí en adelante 27F. Se entiende el manejo de las vulnerabilidades urbano-sociales, como un proceso que se inicia reconociendo las características de los espacios construidos y del tejido social, y que finaliza mediante la propuesta de estrategias de mitigación que disminuyan la condición de riesgo de la localidad de Dichato. Si se asume la resiliencia como la capacidad de los actores sociales y del espacio construido para recuperarse frente a desastres y planificar sustentablemente el territorio, la tesis plantea la existencia de variables de vulnerabilidad urbano-sociales, que debiesen ser manejadas con un objetivo de reconstrucción resiliente, es decir, asumir el potencial de riesgo al que están sometidos las localidades y su comunidad. Por lo tanto, al planificar los nuevos espacios, deberíamos considerar las características propias del territorio y de las eventuales amenazas, considerando, además, el rol de los sujetos sociales de la localidad, la capacidad de organización de la comunidad y las relaciones existentes entre ellos y otros actores público-privados, ya sea a escala local, regional e incluso nacional. La investigación parte del supuesto que en Chile, históricamente las localidades y en específico Dichato, que se emplazan en el borde costero bajo condiciones de riesgo acentuadas por factores de vulnerabilidad urbano-sociales, escasa planificación y gestión del riesgo, exigen pensar en nuevas estrategias y formas de diseño, que aseguren condiciones de resiliencia para la comunidad existente y sus generaciones futuras. Se plantea que una condición de riesgo puede ser mitigada por una condición de resiliencia, donde el manejo de las vulnerabilidades urbano-sociales pueden influir directamente. La investigación es de carácter exploratoria con un enfoque cualitativo y cuantitativo realizada desde fines del 2014 hasta la fecha. Los resultados esperados intentan clarificar que variables urbano sociales debieran considerarse al momento de planificar en condición de riesgo, generando así, nuevas propuestas para diseñar espacios más resilientes, equitativos y sustentables.

APA, Harvard, Vancouver, ISO, and other styles

10

Melnattur, Krishna V. "Novel developmental functions of the Drosophila SOX gene Dichaete." 2008. https://scholarworks.umass.edu/dissertations/AAI3337015.

Full text

Abstract:

All multicellular life begins as a single cell—the fertilised egg, from which the adult organism develops. As a general priniciple, as embryos progess through development, changes in cellular status seem to be effected by cell specific transcription factors which regulate specific gene subsets. The SOX (Sry box) family of transcription factors are one such developmentally important class of transcription factors, consisting of twenty mammalian proteins that each contain a single High Mobility Group (HMG) DNA binding domain that is >50% homologous to that of Sry, the mammalian testes determining factor. SOX proteins are multi-functional developmental regulators that sequence specifically bind DNA, and can function both as classical transcription factors and as architectural components of chromatin (Kiefer et al. 2007, Lefebvre et al. 2007). We have been modeling SOX gene function using the Drosophila SOX gene Dichaete (D). D has similar biochemical properties to mammalian SOX proteins, and is essential for embryonic segmentation and cell fate specification (Ma et al. 1998, Russell et al. 1996). In this thesis I detail novel functions of D in oogenesis and adult olfactory system development. Chapter two details D expression and function during oogenesis in Drosophila. We show that D is transiently expressed in the oocyte cytoplasm from region 2 of the germarium through stage 8. We demonstrate that D protein can bind gürken mRNA, which was mislocalised in D mutant egg chambers. These studies contribute to our understanding of the establishment of dorsal/ventral polarity and significantly detail a cytoplasmic role for SOX proteins in binding mRNA (Mukherjee et al., 2006). Chapter three details the expression and function of D in the adult Drosophila nervous system. I show that D is prominently expressed in a mixture of excitatory and inhibitory local neurons (LNs) and central complex ring neurons. Hypomorphic D alleles were generated, and the mutant brains exhibited misplacement and mistargeting of specific olfactory projection neurons. These data greatly enhance our understanding of the development of neuronal connectivity in a discrete neural map represented by the fly antennal lobe, and represent a detailed report of SOX gene expression in the adult brain.

APA, Harvard, Vancouver, ISO, and other styles

Books on the topic "Dichaete"

1

Institute Of Electrical and Electronics Engineers. High-Intensity-Dicharge and Low-Pressure Sodium Lamps in Luminaires: Guide for Selection (American National Standard for Roadway Lighting Equipment). Institute of Electrical & Electronics Enginee, 1997.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Dichaete"

1

Radionov, V. P., and V. K. Kiseliov. "Terahertz Gas-Discharge Laser with Additional Dicharge Section." In 2007 International Kharkiv Symposium Physics and Engrg. of Millimeter and Sub-Millimeter Waves (MSMW). IEEE, 2007. http://dx.doi.org/10.1109/msmw.2007.4294632.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Yim, Jacqueline H., Giuseppe R. Palmese, Halim Ayan, Alexander Fridman, Victor N. Vasilets, Daphne Pappas, James Hirvonen, and J. Derek Demaree. "Functionalization of Polymers using N2 Pulsed Dielectric Barrier Dicharge." In 2007 IEEE Pulsed Power Plasma Science Conference. IEEE, 2007. http://dx.doi.org/10.1109/ppps.2007.4345743.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Chen, Jianning, Yuanxiang Zhou, Yunzhou Zhao, Ling Zhang, Xin Huang, and Jiamin Ge. "Numerical Simulation of Surface Dicharge in Oil-paper Insulation Under Various Temperatures." In 2021 International Conference on Electrical Materials and Power Equipment (ICEMPE). IEEE, 2021. http://dx.doi.org/10.1109/icempe51623.2021.9509061.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Na, Y. H., C. B. Lee, S. S. Kim, H. Y. Lee, and H. S. Uhm. "ARC dicharge in water to remove algae and red tide in mere/coast." In The 33rd IEEE International Conference on Plasma Science, 2006. ICOPS 2006. IEEE Conference Record - Abstracts. IEEE, 2006. http://dx.doi.org/10.1109/plasma.2006.1707039.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Izquierdo, Eduardo, Jose Gonzalez-Aguilar, and Laurent Fulcheri. "Theoretical and experimental study of an argon free burning arc dicharge at very high-pressure and low-intensity." In 2008 IEEE 35th International Conference on Plasma Science (ICOPS). IEEE, 2008. http://dx.doi.org/10.1109/plasma.2008.4590715.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!