Relevant bibliographies by topics / Dichloroethane – Toxicology

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  1. Journal articles
  2. Dissertations / Theses
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  4. Book chapters

Academic literature on the topic 'Dichloroethane – Toxicology'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Dichloroethane – Toxicology"

1

IGWE, ORISA J., SHANE S. QUE HEE, and W. D. WAGNER. "Interaction between 1,2-Dichloroethane and Disulfiram." Toxicological Sciences 6, no. 4 (1986): 733–46. http://dx.doi.org/10.1093/toxsci/6.4.733.

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IGWE, O. "Interaction between 1,2-dichloroethane and disulfiram I. Toxicologic effects." Fundamental and Applied Toxicology 6, no. 4 (1986): 733–46. http://dx.doi.org/10.1016/0272-0590(86)90186-7.

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Brittebo, E. B., B. Kowalski, H. Ghantous, and I. Brandt. "Epithelial binding of 1,2-dichloroethane in mice." Toxicology 56, no. 1 (1989): 35–45. http://dx.doi.org/10.1016/0300-483x(89)90210-2.

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Li, Wenxue, Liping Chen, Yiwei Su, Hua Yin, Yaqin Pang, and Zhixiong Zhuang. "1,2-Dichloroethane induced nephrotoxicity through ROS mediated apoptosis in vitro and in vivo." Toxicology Research 4, no. 5 (2015): 1389–99. http://dx.doi.org/10.1039/c5tx00056d.

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Yllner, Sven. "Metabolism of 1,2-Dichloroethane-14C in the Mouse." Acta Pharmacologica et Toxicologica 30, no. 3-4 (2009): 257–65. http://dx.doi.org/10.1111/j.1600-0773.1971.tb00657.x.

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Igwe, Orisa J., Shane S. Que Hee, and William D. Wagner. "Interaction between 1,2-dichloroethane and tetraethylthiuram disulfide (disulfiram)." Toxicology and Applied Pharmacology 86, no. 2 (1986): 286–97. http://dx.doi.org/10.1016/0041-008x(86)90059-1.

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Zeng, Ni, Zhen Zhang, Hongmei Jiang, et al. "LncRNA-241 inhibits 1,2-Dichloroethane-induced hepatic apoptosis." Toxicology in Vitro 61 (December 2019): 104650. http://dx.doi.org/10.1016/j.tiv.2019.104650.

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PAYAN, J. P., A. M. SAILLENFAIT, P. BONNET, J. P. FABRY, I. LANGONNE, and J. P. SABATE. "Assessment of the Developmental Toxicity and Placental Transfer of 1,2-Dichloroethane in Rats." Toxicological Sciences 28, no. 2 (1995): 187–98. http://dx.doi.org/10.1093/toxsci/28.2.187.

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Payan, J. "Assessment of the Developmental Toxicity and Placental Transfer of 1,2-Dichloroethane in Rats." Fundamental and Applied Toxicology 28, no. 2 (1995): 187–98. http://dx.doi.org/10.1006/faat.1995.1159.

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Payan, J. P., D. Beydon, J. P. Fabry, M. T. Brondeau, M. Ban, and J. de Ceaurriz. "Urinary thiodiglycolic acid and thioether excretion in male rats dosed with 1,2-dichloroethane." Journal of Applied Toxicology 13, no. 6 (1993): 417–22. http://dx.doi.org/10.1002/jat.2550130608.

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Dissertations / Theses on the topic "Dichloroethane – Toxicology"

1

Govender, Algasan. "Characterisation of chlorinated-hydrocarbon-degrading genes of bacteria." Thesis, 2009. http://hdl.handle.net/10413/1054.

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1,2-dichloroethane (DCA) is one of the most widely used and produced chemicals of the modern world. It is used as a metal degreaser, solvent, chemical intermediate as well as a fuel additive. This carcinogen is toxic to both terrestrial and aquatic ecosystems and accidental spills and poor handling has resulted in contamination of the environment. Thus far several bacteria in the Northern hemisphere have been identified that are capable of utilizing this compound as a sole carbon and energy source. This report focuses on the isolation and characterization of bacterial isolates from the Southern hemisphere that are capable of degrading DCA as well as the global distribution of the DCA catabolic route. Samples obtained from waste water treatment plants were batch cultured in minimal medium containing DCA and repeatedly sub-cultured every five days over a 25 day period. A halogen release assay was performed in order to determine whether individual isolates possessed dehalogenase activity. Confirmation of DCA utilization by bacterial isolates positive for dehalogenase activity was done by sub-culturing back into minimal medium containing DCA. Enzyme activities were confirmed with cell free extracts using all of the intermediates in the proposed DCA degradative pathway and compared to a known DCA degrading microorganism. Biochemical tests and 16SrDNA sequencing indicated that all the South African isolates belonged to the genus Ancylobacter and were different from each other. Based on enzyme activities, it was found that the South African isolates may possess a similar degradative route as other DCA degrading microorganisms. Primers based on genes involved in DCA degradation were synthesized and PCR analysis was performed. It was found that all isolates possessed an identical hydrolytic dehalogenase gene whereas the other genes in the pathway could not be PCR amplified. Southern hybridization using probes based on known genes indicated that some of the isolates had homologous genes. Pulsed field gel electrophoresis (PFGE) and random amplified polymorphic DNA (RAPD) analysis indicated that the five South African isolates of Ancylobacter aquaticus are distinguishable from each other. This study is the first report indicating that microbes from different geographical locations use similar metabolic routes for DCA degradation. The first gene of the pathway (dhlA) has undergone global distribution which may be due to widespread environmental contamination.<br>Thesis (Ph.D)-University of KwaZulu-Natal, Westville, 2009.
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Murenzi, Edwin. "Microtransplantation of Rat Brain Neurolemma into Xenopus Laevis Oocytes to Study the Effect of Environmental Toxicants on Endogenous Voltage-Sensitive Ion Channels." 2017. https://scholarworks.umass.edu/masters_theses_2/520.

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Microtransplantation of mammalian neurolemma into Xenopus laevis oocytes has been used to study ion channels in terms of their structure and function in the central nervous system. Use of microtransplanted neurolemma is advantageous in that tissue can be obtained from various sources, ion channels and receptors are present in their native configuration and they can be used to evaluate numerous channelpathies caused by environmental toxicants. Here we show that Xenopus oocytes injected with fragments of rat brain neurolemma successfully express functional native ion channels that are assembled in their own plasma membrane. Using a high throughput two electrode voltage clamp (TEVC) electrophysiological system, currents that were sensitive to tetrodotoxin (TTX), omega-conotoxin MVIIC, and tetraethylammonium (TEA) were detected, indicating the presence of multiple voltage-sensitive ion channels (voltage-sensitive sodium, calcium and potassium channels, respectively). In this current research, a “proof-of-principle” experiment was conducted where TTX-sensitive voltage-sensitive sodium channel (VSSC) currents were measured. VSSCs are a well-established site of action for 1,1,1-trichloro-2,2-di(4-chlorophenyl)ethane (DDT) but not for its non-toxic metabolite 1,1-bis-(4-chlorophenyl)-2,2-dichloroethene (DDE). A differential sensitivity of DDT versus DDE on TTX-sensitive sodium current in neurolemma-injected oocytes was determined. DDT elicited an increase in depolarization-dependent, TTX-sensitive sodium current while DDE had no significant effect. Additionally, DDT resulted in a slowing of sodium channel inactivation kinetics whereas DDE has no similar effect. These results are consistent with the findings obtained using heterologous expression of single isoforms of rat brain VSSCs by injecting cRNA into Xenopus oocytes. By demonstrating the classic structural activity relationship of DDT and DDE on mammalian voltage-gated sodium channels isolated in rat brain neurolemma, this study supports the use of automated high-throughput electrophysiology to study the effects of various environmental toxicants on multiple mammalian cellular targets. More importantly, using rat brain neurolemma ensures that the proteins of interest have been transcribed and have undergone all the necessary post-translational modifications before they were injected and expressed in the Xenopus oocytes which is not the case for traditional heterologous expression.
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Books on the topic "Dichloroethane – Toxicology"

1

Programme, United Nations Environment, International Labour Organisation, World Health Organization, and Inter-Organization Programme for the Sound Management of Chemicals., eds. 1,1-dichloroethene (vinylidene chloride). World Health Organization, 2003.

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2

1,2-Dichloroethane (BUA Report). Hirzel, 1997.

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3

Corporation, Clement International, and United States. Agency for Toxic Substances and Disease Registry., eds. Toxicological profile for 1,2-dichloroethane. U.S. Dept. of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry, 1994.

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1,2-dichloroethane health and safety guide. World Health Organization, 1991.

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World Health Organization (WHO). 1, 2-dichloroethane (Health & Safety Guides). World Health Organization, 1991.

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Seihin Hyōka Gijutsu Kiban Kikō., Kagaku Busshitsu Hyōka Kenkyū Kikō., and Shin Enerugī Sangyō Gijutsu Sōgō Kaihatsu Kikō (Japan), eds. 1, 2-jikuroroetan: Kagaku busshitsu haishutsu haaku kanri sokushinhō seirei gōbangō 1-116, CAS tōroku bangō 107-06-2 = 1, 2-dichloroethane. Seihin Hyōka Gijutsu Kiban Kikō Kagaku Busshitsu Kanri Sentā, 2007.

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1,1-Dichloroethene. VCH, 1992.

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Corporation, Clement International, and United States. Agency for Toxic Substances and Disease Registry., eds. Toxicological profile for 1,1-dichloroethene. U.S. Dept. of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry, 1994.

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United States. Environmental Protection Agency., Research Triangle Institute, and United States. Agency for Toxic Substances and Disease Registry., eds. Toxicological profile for 1,2-dichloroethene: Update. U.S. Dept. of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry, 1996.

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Book chapters on the topic "Dichloroethane – Toxicology"

1

Ware, George W. "1,2-Dichloroethane." In Reviews of Environmental Contamination and Toxicology. Springer New York, 1988. http://dx.doi.org/10.1007/978-1-4612-3922-2_6.

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2

Syed, I., and S. D. Ray. "Dichloroethane, 1,2-." In Encyclopedia of Toxicology. Elsevier, 2014. http://dx.doi.org/10.1016/b978-0-12-386454-3.01247-1.

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Syed, I. "1,1-Dichloroethane." In Encyclopedia of Toxicology. Elsevier, 2014. http://dx.doi.org/10.1016/b978-0-12-386454-3.00305-5.

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"1,1-DiChloroethane." In Toxicology Desk Reference, edited by Robert P. Ryan, Claude E. Terry, and Sanford S. Leffingwell. Routledge, 2019. http://dx.doi.org/10.1201/9780203735398-59.

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Soni, Madhusudan G., and Harihara M. Mehendale. "Dichloroethanes." In Encyclopedia of Toxicology. Elsevier, 2005. http://dx.doi.org/10.1016/b0-12-369400-0/00313-6.

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"1,1-Dichloroethene." In Toxicology Desk Reference, edited by Robert P. Ryan, Claude E. Terry, and Sanford S. Leffingwell. Routledge, 2019. http://dx.doi.org/10.1201/9780203735398-60.

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"1,2-Dichloroethene." In Toxicology Desk Reference, edited by Robert P. Ryan, Claude E. Terry, and Sanford S. Leffingwell. Routledge, 2019. http://dx.doi.org/10.1201/9780203735398-61.

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You might also be interested in the extended bibliographies on the topic 'Dichloroethane – Toxicology' for particular source types:
Journal articles
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