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1

Cao, T., M. E. Abdo, N. Lakis, N. Gloyeske, and D. Dinh. "Twin-to-Twin Transfusion Syndrome in a Dichorionic Diamniotic Pregnancy with Unusual Ultrasound Findings." American Journal of Clinical Pathology 162, Supplement_1 (2024): S4—S5. http://dx.doi.org/10.1093/ajcp/aqae129.009.

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Abstract Introduction/Objective Twin-to-twin transfusion syndrome (TTTS) is a complication of twin gestations which affects approximately 1-3 per 10,000 births and is most commonly observed in monochorionic diamniotic twins. The authors present a rare case of TTTS occurring in dichorionic diamniotic twins and literature review. Methods/Case Report The patient was initially found to have a twin pregnancy at 12 weeks of gestation with ultrasound findings suggestive of monochorionic diamniotic twins, but subsequent ultrasounds demonstrated a twin- peak sign, indicating a dichorionic diamniotic ge
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2

Kim, Mi Ju, Hyun Mi Kim, Hyun-Hwa Cha, et al. "Perinatal Outcomes and Neurodevelopment 1 Year after Birth in Discordant Twins According to Chorionicity." Medicina 59, no. 3 (2023): 493. http://dx.doi.org/10.3390/medicina59030493.

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Background and Objectives: This study aimed to compare maternal complications, perinatal outcomes, and neurodevelopment 1 year after the birth between concordant and discordant twins in monochorionic and dichorionic twins. Materials and Methods: This retrospective study included twin pregnancies delivered between 24 + 1 and 38 + 2 weeks of gestation between January 2011 and September 2019. Chorionicity was confirmed by ultrasonography and was categorized into monochorionic and dichorionic. Each was then divided into two groups (concordant and discordant) according to birth weight discordancy.
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A., Gigi, Rachel Alexander, and Radhamani K. "Effects of twin pregnancy chorionic properties on fetal outcomes: a comparative study." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 9 (2020): 3802. http://dx.doi.org/10.18203/2320-1770.ijrcog20203860.

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Background: Twins carry significant risks to both mothers and babies. The purpose of this study was to evaluate chorionicity and its impact on perinatal outcomes in twins.Methods: This prospective observational study was conducted in the department of obstetrics and gynecology, Government T. D. Medical College, Alappuzha, Kerala. A total of 106 cases of twin pregnancies were included in the prospective descriptive study. Based on the ultrasound results and methods of the postpartum pathologic examination of the placental membranes, the cases were divided into the twin group with monochorionic
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Vatti, Thanvi, Kathryn Coyne, Sung Tae Kim, Joseph Findley, Rebecca Flyckt, and Rachel Weinerman. "A Case of Sex Discordant Dichorionic Diamniotic Twins after Single Embryo Transfer and the Importance of Zygosity Testing." Reproductive Medicine 4, no. 1 (2023): 34–39. http://dx.doi.org/10.3390/reprodmed4010005.

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Single embryo transfer (SET) is a technique used in assisted reproductive treatment (ART) that is used to promote singleton pregnancies. To date, there are five reported cases of dizygotic twin pregnancies with mothers who underwent SET. Here, we present a sixth case of a dichorionic, diamniotic twin pregnancy with sex discordance. The patient is a 34-year-old woman with unexplained secondary infertility who underwent in vitro fertilization (IVF) and frozen-thawed embryo transfer from a SET. The ultrasonographic images from the first and second trimester scans identified dichorionic, diamnioti
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5

Brouillet, Sophie, Sandie Mereuze, Noémie Ranisavljevic, et al. "Molecular Characterization of a Rare Case of Monozygotic Dichorionic Diamniotic Twin Pregnancy after Single Blastocyst Transfer in Preimplantation Genetic Testing (PGT)." International Journal of Molecular Sciences 23, no. 18 (2022): 10835. http://dx.doi.org/10.3390/ijms231810835.

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Preimplantation genetic testing (PGT) is widely used to select unaffected embryos, increasing the odds of having a healthy baby. During the last few decades, it was accepted that monozygotic dichorionic diamniotic twin pregnancies occurred from the embryo splitting before Day 3 postfertilization according to Corner’s dogma. Hence, the occurrence of a dichorionic diamniotic twin pregnancy after a single blastocyst transfer was considered a dizygotic pregnancy resulting from blastocyst transfer and concurrent natural fertilization. In our study, we have provided for the first time molecular proo
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6

Tregoning, Simone, Wendy Salter, David R. Thorburn, et al. "Fumarase Deficiency in Dichorionic Diamniotic Twins." Twin Research and Human Genetics 16, no. 6 (2013): 1117–20. http://dx.doi.org/10.1017/thg.2013.72.

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Fumarase deficiency is a rare autosomal recessive inborn error of metabolism of the Krebs Tricarboxylic Acid cycle. A heavy neurological disease burden is imparted by fumarase deficiency, commonly manifesting as microcephaly, dystonia, global developmental delay, seizures, and lethality in the infantile period. Heterozygous carriers also carry an increased risk of developing hereditary leiomyomatosis and renal cell carcinoma. We describe a non-consanguineous family in whom a dichorionic diamniotic twin pregnancy resulted in twin boys with fumarase deficiency proven at the biochemical, enzymati
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Shaw, Sailabala, Braja Kishore Behera, Bikash Chandra Nayak, and Gurukrushna Mohapatra. "Incidence and Perinatal Outcomes of Twin Pregnancy in Tertiary Healthcare Facility, Odisha, India." Al-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 ) 5, no. 1S (2023): S157–161. http://dx.doi.org/10.54133/ajms.v5i1s.302.

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Background: Assisted reproductive technology has resulted in a progressive rise in the incidence of twin pregnancies, which affect both mother and child in terms of antepartum complications. Objective: To assess the perinatal outcomes of twin pregnancies and the influence of chorionicity on them in a tertiary healthcare facility. Methods: It is a hospital-based cross-sectional study that was carried out in the Obstetrics and Gynecology Department of S.C.B. Medical College Hospital, Cuttack, during the period from 2013 to 2015. All mothers having twin pregnancies (with 28 weeks of completed ges
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8

Tzafrir, Tuval, Tamar Wainstock, Eyal Sheiner, Shayna Miodownik, and Gali Pariente. "Fetal Growth Restriction and Long-Term Cardiovascular Morbidity of Offspring in Dichorionic–Diamniotic Twin Pregnancies." Journal of Clinical Medicine 12, no. 4 (2023): 1628. http://dx.doi.org/10.3390/jcm12041628.

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Objective: We opted to investigate whether fetal growth restriction (FGR) in dichorionic–diamniotic twins is a risk factor for long-term cardiovascular morbidity in offspring. Study design: A population-based retrospective cohort study, comparing long-term cardiovascular morbidity among FGR and non-FGR twins, born between the years 1991 and 2021 in a tertiary medical center. Study groups were followed until 18 years of age (6570 days) for cardiovascular-related morbidity. A Kaplan–Meier survival curve compared the cumulative cardiovascular morbidity. A Cox proportional hazard model assisted wi
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9

Kaul, Anita, Smriti Prasad, Keerthana Anand, Saloni Arora, and Akshatha Sharma. "Elective Fetal Reduction in Dichorionic Diamniotic Twin Pregnancies on Parental Request: A Single-Centre Experience." Fetal Diagnosis and Therapy 48, no. 4 (2021): 272–78. http://dx.doi.org/10.1159/000513581.

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<b><i>Objectives:</i></b> Our study aimed to examine a subset of electively reduced twins and compare their outcomes with those of expectantly managed twins, along with a cohort of singleton pregnancies. The secondary aim was to ascertain the procedure-related miscarriage risks. <b><i>Methods:</i></b> A retrospective cohort analysis was performed at Apollo Centre for Fetal Medicine, New Delhi, comparing pregnancy outcomes in dichorionic diamniotic twin pregnancies which were reduced to singletons (group 1) with that of women with dichorionic twin
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10

Tu, William, Jane Chueh, and William Kennedy. "Dichorionic Diamniotic Twin Pregnancy Discordant for Bladder Exstrophy." Advances in Urology 2009 (2009): 1–3. http://dx.doi.org/10.1155/2009/186483.

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A 38 year-old woman presented with a dichorionic diamniotic twin pregnancy at gestational age of 32 weeks concerning for an abdominal wall mass in one of the twins. Initial ultrasound evaluation was suspicious for an omphalocele, but the affected twin was found to have bladder exstrophy at birth. This illustrates the difficulties of accurate prenatal diagnosis of bladder exstrophy in a twin pregnancy at a late gestation.
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11

Ozler, S., E. Oztas, B. Gumus Guler, et al. "3Ds: decorin, discordance, and diamniotic dichorionic twins." Clinical and Experimental Obstetrics & Gynecology 44, no. 2 (2017): 239–43. http://dx.doi.org/10.12891/ceog3378.2017.

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12

Sala, Valentina, Luigina Spaccini, Stefano Faiola, et al. "Monochorionic Diamniotic Twins with Sex Discordance: Case Series." Diagnostics 15, no. 3 (2025): 372. https://doi.org/10.3390/diagnostics15030372.

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Background and Clinical Significance: Ultrasonographic diagnosis of twin pregnancies has become routine, with chorionicity playing a crucial role in assessing associated risks. Traditionally, monochorionic (MC) twins were believed to derive from a single zygote, ensuring sex concordance. However, recent cases of dizygotic monochorionic (MCDZ) twins challenge this paradigm. In this paper, four cases of MCDZ twins with sex discordance are described. Case presentation: Case 1 and case 2 describe two spontaneous MC/diamniotic twin pregnancies in which sex discordance between twins was attributed t
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13

Jeyamani, B., M. Divya, and S. Senthil Priya. "Two Succenturiate Placentas in Dichorionic/Diamniotic (DC/DA) Twins – A Very Rare Case Presentation." Medical Journal of Dr. D.Y. Patil Vidyapeeth 18, no. 1 (2025): 136–38. https://doi.org/10.4103/mjdrdypu.mjdrdypu_947_23.

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ABSTRACT This patient is a 45-year-old primigravida had conceived by fresh embryo transfer. ultrasound sonograph (USG) showed a dichorionic/diamniotic (DC/DA) type of twin. Serial ultrasounds showed normal growth and amniotic fluid levels for both twins. Cesarean section was done at 35 weeks. Both infants were admitted in the neonatal intensive care unit (NICU). The uniqueness of this case is the placenta, identified as dichorionic with two separate succenturiate lobes connected to the main placenta through communicating vessels. This exceptional case of placental variation, emphasises the imp
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14

Patel, Tehsin, Pragati Sathe, Swati Singh, R. R. Prashanth, Sruthi Nair, and Anitha Haribalakrishna. "Fatal disseminated congenital cytomegalovirus infection in a twin preterm neonate: A clinical-pathological diagnosis." Wadia Journal of Women and Child Health 3 (November 23, 2024): 99–103. http://dx.doi.org/10.25259/wjwch_32_2024.

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We report on a rare case of congenital cytomegalovirus (CMV) in a dichorionic diamniotic twins. The uniqueness of one of the twins having a fatal disseminated CMV infection with the other twin being normal has been discussed. In cases with no antenatal diagnosis, the role of post-clinical-pathological correlation using fetal autopsy has been described with fetal autopsy images (gross and microscopy). The possible immunological basis for the selective affection of one twin and a review of literature on similar cases have also been done.
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15

Tepla, I. "COMPARATIVE ANALYSIS OF THE NEONATE BIRTH WEIGHT IN DIFFERENT TYPES OF TIN PREGNANCY." Medical Science of Ukraine (MSU) 17, no. 1 (2021): 35–46. http://dx.doi.org/10.32345/2664-4738.1.2021.05.

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The relevance of the study lies in the significant increase in multiple pregnancies connected with the higher risk of perinatal complications, the controversy over the effects of chorionicity and sex of the babies on their birth weight, the need for timely diagnosis of fetal growth restriction, and associated morbidity.
 The objective of this study was to compare fetal weights at the birth of different variants of twins depending on chorionicity, gestational age, and sex.
 Materials and methods. During 2016-2020, 440 pairs of twins were examined: 375 dichorionic diamniotic and 65 mon
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16

Прибушеня, О. В., О. Л. Зобикова, and Е. Н. Главацкая. "Dichorionic Diamniotic Twin with Down Syndrome and Anoftalm in Both Fetuses." Репродуктивное здоровье. Восточная Европа, no. 1 (February 22, 2022): 89–94. http://dx.doi.org/10.34883/pi.2022.12.1.010.

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Представлено клиническое наблюдение дихориальной диамниотической (ДХДА) монозиготной (МЗ) двойни, завершившейся рождением двух девочек с двусторонним анофтальмом и трисомией 21. В семье имеется ребенок с односторонним микрофтальмом. Обсуждаются характер заболевания близнецов, природа происхождения двойни, генетический риск и ошибки, допущенные на этапе пренатальной диагностики. Диагностика синдрома Дауна у близнецов вызвала затруднения в связи с измененным фенотипом, связанным с двусторонним анофтальмом. We present a clinical observation of dichorionic diamniotic (DHDA) monozygotic (MZ) twins
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17

Boesveld, Merel, and Marieke A. C. Hemels. "Discordant Transient Extreme Hyperleukocytosis in Dichorionic Diamniotic Twins." Journal of Pediatric Hematology/Oncology 38, no. 3 (2016): 246–47. http://dx.doi.org/10.1097/mph.0000000000000503.

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18

Tepla, Iryna, and Andrii Tkachenko. "Morphometric parameters of placentas in dichorionic diamniotic twins." European Journal of Obstetrics & Gynecology and Reproductive Biology 234 (March 2019): e49. http://dx.doi.org/10.1016/j.ejogrb.2018.08.261.

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19

Zabelina, T. M., A. Yu Kostinova, I. V. Krasnopolskaya, and R. G. Shmakov. "PREGNANCY MANAGEMENT AND DELIVERY IN A PATIENT WITH PLACENTA ACCRETA IN DICHORIONIC DIAMNIOTIC TWINS: A CASE REPORT." Sibirskij medicinskij vestnik 9, no. 2 (2025): 78–84. https://doi.org/10.31549/2541-8289-2025-9-2-78-84.

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Introduction. Placenta accreta is associated with the risk of massive bleeding both during pregnancy and during operative delivery. Multiple pregnancies are also associated with massive blood loss during cesarean section. The presence of placenta accreta in twin pregnancy is a severe case and presents difficulties for performing organ-preserving surgery. Aim of the research. Description of a clinical case of pregnancy management and delivery of a patient with placenta accreta in dichorionic diamniotic twins. Materials and methods. The article presents a clinical observation of pregnancy manage
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20

Gordeeva, E. K., A. V. Pomortsev, I. B. Vasina, M. A. Asriants, and T. A. Sadovnikova. "Foeto-foetal transfusion syndrome in dichorionic diamniotic twins: a clinical case." Kuban Scientific Medical Bulletin 28, no. 2 (2021): 120–34. http://dx.doi.org/10.25207/1608-6228-2021-28-2-120-134.

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Background. Management of multiple gestation complicated by the foeto-foetal transfusion syndrome is among most intricate modern obstetric issues. The syndrome develops in 10–20% of monochorionic diamniotic twins leading to 80–100% mortality in one or both twins if left uncorrected, especially in early syndrome cases. Although foeto-foetal transfusion usually develops with monochorionic placentae, there are notable exceptions of vascular placental anastomoses reported with dichorionic monozygotic twins. The disease supposedly entails from an imbalanced blood interflow between dichorionic twins
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Nkyekyer, Kobinah, and Theodore Boafor. "Pattern of Twin Placentation in Ghana." Twin Research and Human Genetics 10, no. 1 (2007): 219–23. http://dx.doi.org/10.1375/twin.10.1.219.

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AbstractA 2-year study involving macroscopic examination of twin placentae was conducted at the Korle Bu Teaching Hospital in Accra, Ghana to determine the proportions of the various types of twin placentation, cord insertions and number of cord vessels and their relationships. Of 765 twin-pair placentae examined, 398 (52%, 95% confidence interval [CI] 48.4%–55.6%) had fused dichorionic, 247 (32.3%, 95% CI 29.0%–35.7%) had separate dichorionic, and 119 (15.6%, 95% CI 13.1%–18.4%) had monochorionic diamniotic placentae; only one (0.1%, 95% CI 0.0%–0.8%) had monochorionic monoamniotic placentati
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Sahu, Bharti, and Pooja Jain Jain. "Incidence and maternal outcome of twin pregnancy." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 11 (2018): 4506. http://dx.doi.org/10.18203/2320-1770.ijrcog20184497.

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Background: Twin pregnancy is a high-risk pregnancy with different prevalences in different regions of world which is on the rise due to growing use of assisted reproductive technology. The objective of this study is to determine the incidence and maternal complication and outcome of twin pregnancies.Methods: This is a prospective observational study conducted in 2016-2017 in NSCB medical college and hospital, Jabalpur on 67 twin deliveries. Final outcome was given in terms of percentage and ratio.Results: After assessment of 5995 deliveries during the period 2016-2017 the incidence of twin pr
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Hefila, Nermeen Mohamed. "Factors affecting time of spontaneous delivery of dichorionic diamniotic twin pregnancy." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, no. 8 (2021): 2961. http://dx.doi.org/10.18203/2320-1770.ijrcog20212941.

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Background: The incidence of twin pregnancy has markedly increased recently due to ART and advanced maternal age. The mother may also experience higher obstetrical morbidity and mortality rates. Aim of the work was to investigate factors affecting the time of spontaneous delivery in dichorionic diamniotic twin pregnancy to improve perinatal outcomes.Methods: The study was a cross-sectional study had been conducted at Elshatby university maternity hospital between October 2019 to May 2020 on 150 cases of dichorionc diamniotic twins pregnancy admitted for spontaneous delivery.History was taken f
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Tepla, Iryna, Andrii Tkachenko, and Valerii Teplyi. "ASSOCIATION BETWEEN PLACENTAL MORPHOMETRIC PARAMETERS AND BIRTH WEIGHT IN DICHORIONIC DIAMNIOTIC TWINS." Wiadomości Lekarskie 75, no. 2 (2022): 427–32. http://dx.doi.org/10.36740/wlek202202118.

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The aim: To assess morphometric parameters of placentas and to evaluate the correlation between the placental disk shape, the site of the umbilical cord insertion and the birth weight of dichorionic twins. Materials and methods: The geometry of placentas, distances between umbilical cord insertion sites and the centroids of the disks were measured in 135 pairs of dichorionic diamniotic twins. The impact of the above-mentioned parameters on the birth weight and placental mass was analyzed. Results: In terms of weight and geometric parameters of placentas, no proven discrepancy between different
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Kunzier, Nadia B., Baraa Allaf, Martin R. Chavez, Diana Abenanti-Richmond, and Anthony M. Vintzileos. "Disentanglement of Discordant Monochorionic-Monoamniotic Twins in a Triplet Pregnancy: An Innovative Approach Utilizing Fetoscopic Laser Coagulation with Micro-Laparoscopic Scissor Dissection." Fetal Diagnosis and Therapy 40, no. 4 (2015): 303–5. http://dx.doi.org/10.1159/000436961.

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Triplet gestations are associated with high perinatal morbidity. Dichorionic-diamniotic triplet pregnancies with growth discordance, polyhydramnios and structural anomalies carry a significantly increased risk of fetal morbidity and mortality from the baseline risks of high-order multiple pregnancies. Intrauterine fetal death of one fetus of a monochorionic pregnancy may cause neurological injury to the surviving fetus. We present a case where an innovative technique was created combining use of the fetoscopic laser and miniature laparoscopic instruments to selectively reduce and disentangle t
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Tepla, Iryna. "Influence of the placental cord insertion site on the placental mass and the birth weight in dichorionic diamniotic twins." EUREKA: Health Sciences, no. 4 (July 30, 2021): 3–11. https://doi.org/10.21303/2504-5679.2021.001843.

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The aim of the study was to determine the effect of the displacement of the umbilical cord insertion site from the centre of the placenta on the placental mass and the birth weight of dichorionic diamniotic twins and to consider the importance of the direction of the displacement, as well as to assess the influence of the umbilical cord displacement on the placental mass and the birth weight of dichorionic diamniotic twins taking into account the direction of displacement. Material and methods. The study was performed on 135 dichorionic diamniotic pairs: 68 opposite-sex, 35 same-sex males, and
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Kyono, Koichi. "The Precise Timing of Embryo Splitting for Monozygotic Dichorionic Diamniotic Twins: When Does Embryo Splitting for Monozygotic Dichorionic Diamniotic Twins Occur? Evidence for Splitting at the Morula/Blastocyst Stage From Studies of In Vitro Fertilization." Twin Research and Human Genetics 16, no. 4 (2013): 827–32. http://dx.doi.org/10.1017/thg.2013.32.

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There is a long-held credo, as illustrated in Langman's Medical Embryology (11th ed., Sadler, 2010), that dichorionic diamniotic (DD) twins develop after embryo splitting in the early stages of embryonic development. However, from our clinical experiences of the examination of data from single-embryo transfers in 16 fertility clinics in Japan and from various reports, the majority of occurrences of DD twins have been found in the blastocyst stages.
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Wilkof Segev, Renana, Milana Gelman, Esther Maor-Sagie, Alon Shrim, Mordechai Hallak, and Rinat Gabbay-Benziv. "New reference values for biometrical measurements and sonographic estimated fetal weight in twin gestations and comparison to previous normograms." Journal of Perinatal Medicine 47, no. 7 (2019): 757–64. http://dx.doi.org/10.1515/jpm-2019-0207.

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Abstract Objective To construct new reference values for biometrical measurements and sonographic estimated fetal weight (sEFW) in twin gestations and compare them to previously published normograms. Methods A retrospective analysis of sEFW evaluations of twin gestations was performed between 2011 and 2016 in a single university-affiliated medical center. sEFW was calculated using the Hadlock 1985 formula. To avoid selection bias, one evaluation per pregnancy was randomly selected. Following mathematical transformation to obtain normality of values, normograms were constructed using a best-fit
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Sinduja, TP, Nazira Sadique, and Pavithra LNU. "Mono Fetal Demise in Twin Gestation and Outcome." Journal of South Asian Federation of Obstetrics and Gynaecology 7, no. 3 (2015): 199–201. http://dx.doi.org/10.5005/jp-journals-10006-1356.

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ABSTRACT We present two cases of dichorionic diamniotic (DCDA) twin and one monochorionic diamniotic (MCDA) twin during their third trimester with single intrauterine fetal demise (IUFD) and their outcomes. These cases were not found to be associated with any of the high-risk factor for fetal demise in twin like abruption placenta, velamentous insertion of cord or cord entanglement.1 Between the DCDA twins, one case developed coagulation disorder, the other case developed acute fatty liver of pregnancy after 2 weeks of diagnosing IUFD and emergency termination was done. Whereas the MCDA twin s
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Kawachiya, S., N. Shimada, K. Kato, T. Segawa, Y. Takehara, and O. Kato. "Incidence of dichorionic diamniotic twins after single blastocyst transfer." Fertility and Sterility 90 (September 2008): S68. http://dx.doi.org/10.1016/j.fertnstert.2008.07.838.

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Kumar, Rakesh, Purnima Upreti, Namrata Malik, Om Kumari, and Neha Dagar. "Fetus Papyraceous in Diamniotic Dichorionic Twins: A Rare Entity." Journal of South Asian Federation of Obstetrics and Gynaecology 15, no. 3 (2023): 347–48. http://dx.doi.org/10.5005/jp-journals-10006-2240.

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Safo, Yaw Abrefa, Dorothy Sackey, and Theophilus Ben Sabi. "Fetus Papyraceous: A Rare Clinical Entity in Dichorionic-Diamniotic Twin Pregnancy." Journal of Advances in Medicine and Medical Research 37, no. 7 (2025): 1–5. https://doi.org/10.9734/jammr/2025/v37i75876.

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Fetus papyraceous, a high order pregnancy complication with an incidence of 1:12,000 pregnancies and 1:200 in twin pregnancies, is a rare condition in which an intrauterine death of one fetus occurs causing mechanical compression over a period. The most concern for the pregnant woman remains the status of the life fetus and any unforeseeable complications. Genetically, the cause is unknown but may be related to poor antenatal screening, low socioeconomic status and certain maternal co-morbidities. Rarely, it could result in intrauterine death of the surviving twin, preterm labor, coagulopathy,
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Tal, Reshef, Dmitry Fridman, and Richard V. Grazi. "Monozygotic Triplets and Dizygotic Twins following Transfer of Three Poor-Quality Cleavage Stage Embryos." Case Reports in Obstetrics and Gynecology 2012 (2012): 1–4. http://dx.doi.org/10.1155/2012/763057.

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Background. Assisted reproductive technology has been linked to the increased incidence of monozygotic twinning. It is of clinical importance due to the increased risk of complications in multiple pregnancies in general and in monozygotic twins in particular.Case. A 29-year-old female, nulligravida underwent her first IVF cycle. Three poor-quality cleavage stage embryos were transferred resulting in monochorionic triamniotic triplets and dichorionic diamniotic twins. Selective embryo reduction was performed at 12 weeks leaving dichorionic twins. The patient underwent emergency cesarean section
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Konno, Hiroko, Takeshi Murakoshi, Kiyonori Miura, and Hideaki Masuzaki. "The Incidence of Dichorionic Diamniotic Twin Pregnancy After Single Blastocyst Embryo Transfer and Zygosity: 8 Years of Single-Center Experience." Twin Research and Human Genetics 23, no. 1 (2020): 51–54. http://dx.doi.org/10.1017/thg.2020.5.

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AbstractDichorionic diamniotic (DCDA) twin pregnancies after single blastocyst embryo transfer have been reported recently, although a blastocyst ovum is generally believed to divide into monochorionic twin pregnancy. We investigated the incidence of DCDA twin pregnancy after single blastocyst embryo transfer and their zygosity. This prospective cohort study included 655 consecutive twin pregnancies that were managed from 2006 to 2014 at our institution. Chorionicity and amnionicity were determined using first-trimester ultrasonography and/or placental pathology. Zygosity was analyzed if the c
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Tepla, Iryna. "Influence of the placental cord insertion site on the placental mass and the birth weight in dichorionic diamniotic twins." EUREKA: Health Sciences, no. 4 (July 30, 2021): 3–11. http://dx.doi.org/10.21303/2504-5679.2021.001843.

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The aim of the study was to determine the effect of the displacement of the umbilical cord insertion site from the centre of the placenta on the placental mass and the birth weight of dichorionic diamniotic twins and to consider the importance of the direction of the displacement, as well as to assess the influence of the umbilical cord displacement on the placental mass and the birth weight of dichorionic diamniotic twins taking into account the direction of displacement.
 Material and methods. The study was performed on 135 dichorionic diamniotic pairs: 68 opposite-sex, 35 same-sex male
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36

Aayushi, Suthar, Panchal Payal, Suthar Harsh, Ghanchi Svija, and Ghanchi Rahil. "Study of Fetomaternal Outcome in Multifetal Gestation." International Journal of Pharmaceutical and Clinical Research 16, no. 11 (2024): 1812–15. https://doi.org/10.5281/zenodo.14517330.

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<strong>Introduction:</strong>&nbsp;A multiple pregnancy may be the result of the fertilization of a simple egg that splits to create identical fetuses or it may be the result of the fertilization of multiple eggs that fraternal fetus or it may be the combination of these both.&nbsp;<strong>Aims and Objectives:&nbsp;</strong>This prospective study was conducted over one year aimed to investigate the fetal and maternal outcome in multifetal gestation. The study included women with multiple pregnancy at or after 26 weeks of gestation who delivered in our hospital, excluding women with multiple p
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Avani, Ahuja, Vijayan Jesmitha, Parihar Bharti, and Yadav Babli. "Study of Maternal Outcome in Twin Pregnancy Based on Chorionicity." International Journal of Pharmaceutical and Clinical Research 15, no. 5 (2023): 1223–34. https://doi.org/10.5281/zenodo.12597920.

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<strong>Objective:&nbsp;</strong>To study the maternal morbidity &amp; mortality in twin gestations &nbsp;&nbsp;&nbsp;according to chorionicity and predict the course of twin pregnancy.&nbsp;<strong>Methods:&nbsp;</strong>All Women with twin pregnancies attending the antenatal OPD, antenatal ward, labour were included in the study, according to inclusion criteria. All the data were collected with the help of pre structured pre tested proforma. The detailed history and through physical and obstetric examination along with relevant investigation were done, risk factors if any were noted. Determi
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Jain, Priyanka, Versha Jain, and Gaurav Damdar. "Dichorionic Diamniotic Twin Pregnancy with Delayed Delivery of the Second Twin (Anachronous Twins)." Journal of South Asian Federation of Obstetrics and Gynaecology 17, no. 1 (2025): 92–94. https://doi.org/10.5005/jp-journals-10006-2583.

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39

Eleftheriades, Anna, Panagiotis Christopoulos, Elsa Tsapakis, et al. "Conjoined Twins Complicating a Dichorionic Triplet Pregnancy after Intracytoplasmic Sperm Injection: A Case Report and Review of the Literature." Children 9, no. 10 (2022): 1549. http://dx.doi.org/10.3390/children9101549.

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Conjoined twins represent a rare type of monoamniotic twins. Ultrasound assessment during the first trimester can facilitate the diagnosis, however further assessment by colour Doppler studies, 3D imaging, fetal echocardiography and fetal magnetic resonance imaging (MRI) is usually required in order to determine the specific fetal abnormalities and to guide appropriate pregnancy management. This case report presents a rare case of conjoined twins complicating a dichorionic-diamniotic triplet pregnancy, achieved after intracytoplasmic sperm injection (ICSI) and blastocyst transfer. A 44-year-ol
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40

Pimentel, Jason D., Linda J. Szymanski, Linoj P. Samuel, and Frederick A. Meier. "DiscordantStreptococcus agalactiae(Group B Streptococcus) Gestational Infection in Monochorionic/Diamniotic and Dichorionic/Diamniotic Twins." Fetal and Pediatric Pathology 31, no. 3 (2012): 176–83. http://dx.doi.org/10.3109/15513815.2012.659394.

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41

Nitta, Emiko, Kenji Kanenishi, Nobuhiro Mori, Mohamed Ahmed Mostafa AboEllail, and Toshiyuki Hata. "Twin fetal facial expressions at 30–33+6 weeks of gestation." Journal of Perinatal Medicine 47, no. 9 (2019): 963–68. http://dx.doi.org/10.1515/jpm-2019-0127.

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Abstract Objective To assess the characteristics of twin fetal facial expressions at 30–33 + 6 weeks of gestation using four-dimensional (4D) ultrasound to clarify twin fetal brain development and maturation. Methods Frequencies of seven fetal facial expressions were studied using 4D ultrasound for 15 minutes in 30 singleton pregnancies and 18 twin pregnancies [four monochorionic diamniotic (MD) and 14 dichorionic diamniotic (DD) twins] at 30–33 + 6 weeks of gestation. Comparison of the frequency in each facial expression was performed between singleton and twin fetuses. Results Mouthing was t
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Belogolovkin (F), Victoria, Stephanie Engel, Lauren Ferrara, Larry Rand, Keith Eddleman, and Joanne Stone. "Does placental location affect fetal birthweight in diamniotic dichorionic twins?" American Journal of Obstetrics and Gynecology 193, no. 6 (2005): S146. http://dx.doi.org/10.1016/j.ajog.2005.10.582.

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43

Gond, Sneha, Partha Pratim Sharma, Narra Madhuri, and Kasturi Barman. "Foetomaternal outcome in multifoetal pregnancy in a tertiary rural teaching hospital." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, no. 2 (2021): 614. http://dx.doi.org/10.18203/2320-1770.ijrcog20210314.

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Background: Aim of the study was to find out foeto-maternal outcome of multifoetal pregnancy in relation to chorionicity and to analyse the associated risk factors.Methods: This study was a prospective observational study on multifoetal pregnancy conducted at Midnapore medical college and hospital. Statistical analysis was done by chi-square test and statistical significance was set at p-value&lt;0.05.Results: Incidence of multifoetal pregnancy was 1.7%. Modal age group was 20-24 years age and 82% conceived spontaneously. Among chorionicity, Dichorionic diamniotic (DCDA) were 60% followed by 3
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Sorrenti, Sara, Asma Khalil, Francesco D’Antonio, et al. "Counselling in Fetal Medicine: Complications of Monochorionic Diamniotic Twin Pregnancies." Journal of Clinical Medicine 13, no. 23 (2024): 7295. https://doi.org/10.3390/jcm13237295.

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Twin pregnancies are at increased risk of morbidity and mortality compared to singletons. Among all twins, monochorionic pregnancies are at higher risk of specific and non-specific complications compared to dichorionic pregnancies. Therefore, it is of great importance to properly counsel future parents with monochorionic pregnancies regarding the risks of adverse outcomes and the modalities of monitoring and intervention of the potential complications. Conditions related to the monochorionicity include twin-to-twin transfusion syndrome (TTTS), twin reversed arterial perfusion sequence (TRAP),
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Derom, Catherine, Evert Thiery, Bart P. F. Rutten, et al. "The East Flanders Prospective Twin Survey (EFPTS): 55 Years Later." Twin Research and Human Genetics 22, no. 6 (2019): 454–59. http://dx.doi.org/10.1017/thg.2019.64.

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AbstractThe East Flanders Prospective Twin Survey (EFPTS) is a registry of multiple births in the province of East Flanders, Belgium. Since its start in 1964, over 10,000 twin-pairs have been registered. EFPTS has several unique features: it is population-based and prospective, with the possibility of long-term follow-up; the twins (and higher order multiple births) are recruited at birth; basic perinatal data are recorded; chorion type and zygosity are established; since 1969, placental biopsies have been taken and frozen at –20°C for future research. Since its origin, the EFPTS has included
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Vashistha, Preeti, Poonam Kashyap, Ashok Kumar, Chetna A. Sethi, and Shivangini Rana. "Fetus papyraceous, a rare complication of twin pregnancy: case report." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, no. 1 (2020): 361. http://dx.doi.org/10.18203/2320-1770.ijrcog20205799.

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Fetus papyraceous or compressus is the mummified fetus associated with multiple gestation, where one fetus dies in early second trimester, flattened, mummified and compressed between the membranes of the living fetus and the uterine wall. It is more common in monozygotic twins but may occur in dizygotic variety. However, the maternal and fetal complications in affected cases can be severe. We present a case that was diagnosed as dichorionic diamniotic twin gestation in early pregnancy which subsequently resulted in the fetal demise of one twin in second trimester leading to fetus papyraceus, b
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French, Christopher A., Frederick R. Bieber, David H. Bing, and David R. Genest. "Twins, placentas, and genetics: Acardiac twinning in a dichorionic, diamniotic, monozygotic twin gestation." Human Pathology 29, no. 9 (1998): 1028–31. http://dx.doi.org/10.1016/s0046-8177(98)90213-1.

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48

Ehman, Dylan, Veronica Mugarab Samedi, Kaarthigeyan Kalaniti, and Sibasis Daspal. "Neonatal Escherichia coli infection in twins: clinical spectrum and management dilemma." BMJ Case Reports 14, no. 1 (2021): e238470. http://dx.doi.org/10.1136/bcr-2020-238470.

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The clinical manifestation of Escherichia coli could vary from asymptomatic bacteraemia to systemic bloodstream infection and meningitis. We describe an unusual course of E. coli infection in twins, emphasising commencement of appropriate antimicrobial therapy. A set of male dichorionic diamniotic twins were delivered at 34 weeks of gestation by caesarian section. Pregnancy was complicated by diabetes, pre-eclampsia and cholestasis. Antenatal ultrasounds noted a congenital pulmonary airway malformation in twin A. Following delivery, twin A developed respiratory distress, but twin B was asympto
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Wetzler, Sara, Meralis Lantigua-Martinez, Sara G. Brubaker, and Judith Chervenak. "Third trimester diagnosis of body stalk anomaly in a dichorionic diamniotic twin pregnancy." BMJ Case Reports 18, no. 6 (2025): e264983. https://doi.org/10.1136/bcr-2025-264983.

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This is a case report of a G1P0 woman in her early 30s with a dichorionic diamniotic twin gestation with limited prenatal care and a third trimester diagnosis of body stalk anomaly (BSA) in one of the twins. Initially diagnosed with an omphalocele, the patient established care in our centre at 31 weeks gestation, and numerous anomalies were noted on ultrasound. However, definitive characterisation was limited by the advanced gestational age and maternal body habitus. Fetal MRI clearly demonstrated anomalies consistent with BSA. A scheduled caesarean delivery was performed at 36 weeks in the se
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Jang, Won-Kyu. "Successful Delayed Interval Delivery in Twin Pregnancy After Early Premature Rupture of Membranes of a Leading Fetus: A Case Report." Medicina 60, no. 11 (2024): 1800. http://dx.doi.org/10.3390/medicina60111800.

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A 36-year-old primigravida conceived dichorionic diamniotic twins via in vitro fertilization. The first twin experienced premature rupture of membranes at 18 weeks and 5 days of gestation. Despite antibiotic treatment, the first fetus suffered intrauterine fetal death and was delivered three days later at 19 weeks and 1 day. Using ritodrine, the remaining umbilical cord was repositioned, and an emergency cerclage was performed. Ritodrine was continuously administered post-surgery but discontinued at 24 weeks and 3 days due to improved uterine contractions. The patient later delivered a healthy
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