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Heathfield, Heather. "Differential diagnosis and decision support in histopathology." Thesis, Open University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.254735.
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Blosser, Peter, Remil Simon, and Courtney Ridner. "Differential Diagnosis of Pan-Uveitis: Behçet’s Disease." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/asrf/2018/schedule/2.
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This report describes the case of a 56-year-old man who presented with blurry vision, increased intraocular pressure, and conjunctival injection after posterior chamber intraocular lens implantation. Initially post-operative endophalmitis and foreign body inflammation were considered as differential diagnoses, but after further examination pan-uveitis was diagnosed. Uveitis is an ocular finding that may indicate several diseases, one of which is Behçet’s Disease. During the interview, the patient mentioned a history of apthous ulcers and genital ulcers which then lead to the clinical diagnosis of Behçet’s Disease. This report emphasizes that Behçet’s Disease is rare in Caucasians. Therefore, is frequently misdiagnosed in North America due to variable presentations and by not exploring the option when analyzing differential diagnoses. Early diagnosis and intervention will prevent the development of blindness and fatality due to complications of the disease.
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Fernandes, Darcy [UNESP]. "Leucoplasia oral e leucoplasia verrucosa proliferativa: um estudo clínico comparativo." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/149217.
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000874686.pdf: 842380 bytes, checksum: 1fee33ddb0a32a78cc9d3d8bf6b6f0cf (MD5)<br>O carcinoma espinocelular (CEC) representa mais de 95% de todas as neoplasias malignas que acometem a cavidade oral e muitas vezes estes tumores são precedidos por alterações clínicas que apresentam um evidente potencial de transformação maligna, as quais são chamadas de desordens potencialmente malignas orais (DPMO). Dentre estas, a leucoplasia oral (LO) é a principal condição dentre as DPMOs com uma taxa de incidência igual a 3,4% e uma taxa de transformação maligna que varia de 0,2% até 17,5%. Uma forma menos reconhecida e ainda pouco compreendida de LO denominada leucoplasia verrucosa proliferativa (LVP), representa uma variante de comportamento persistente e progressivo para malignidade, com uma taxa de transformação maligna ocorrendo em mais de 70% dos casos. O diagnóstico da LVP atualmente só é possível através da observação temporal e individual de cada paciente, com a demonstração de progressão clínica e histológica das lesões para um CEC. A dificuldade no diagnóstico precoce da LVP decorre da sobreposição de características clínicas e histopatológicas, especialmente em casos de LO multifocal convencional. Portanto, foi proposto inicialmente realizar a classificação de casos multifocais de LO encontrados no Serviço de Medicina Bucal da Faculdade de Odontologia de Araraquara - UNESP, durante os anos de 1995 até 2015, segundo descrição da Organização Mundial da Saúde (OMS, 2005) e critérios diagnósticos para LVP atualmente propostos por Cerero-Lapiedra (2010) e Carrard (2013). Posteriormente, foi realizada uma análise comparativa entre as características clínicas e microscópicas de casos de LVP e LO. Os resultados deste estudo revelaram que dentre 86 casos de LO, 45 casos apresentaram o envolvimento de dois ou mais sítios orais configurando estes como casos de LO multifocal. Segundo avaliação realizada por dois observadores experientes...(Resumo completo, clicar acesso eletrônico abaixo)<br>The squamous cell carcinoma (SCC) represent more than 95% of all the malignant neoplasia of the oral cavity and most of times these tumors are preceded by clinical conditions that have a potential for malignant transformation called oral potentially malignant disorders (OPMD). Among these, the oral leukoplakia (OL) is the most important OPMD, with an incidence rate of 3.4% and a malignant transformation from 0.2 to 17.5%. A form less recognized and poorly understood of leukoplakia is the proliferative verrucous leukoplakia (PVL) which represents a variant with a persistent and progressive to malignancy behavior, with a malignant transformation ratio up to 70% of cases. Currently, the diagnosis of PVL is only made by the temporal and individual observation of each patient, with the demonstration of clinical and histopathological progression to an SCC. The difficult to stablish an early diagnosis of PVL comes from the overlap of clinical and histopathological features with conventional multifocal OL cases. Therefore, was initially proposed to perform a classification of multifocal OL cases found in the Oral Medicine Service from the Araraquara Dental School - UNESP, between 1995 and 2015, according to the WHO definition (WHO, 2005) and the current suggested diagnostic criteria for PVL by Cerero-Lapiedra (2010) and Carrard (2013). Lately, a comparative analysis was conducted between the clinical and microscopic features from cases of PVL and OL. The results of this study revealed that between 86 cases of OL, 45 presented involvement of two or more setting this as multifocal OL cases. According to the evaluation by two experts, 14/45 were considered true cases of PVL. The classification of the same 45 cases by the WHO definition revealed 21/45 cases as PVL, by the Cerero-Lapiedra 27/45 cases were PVL and 4/45 cases were PVL according to Carrard. Sensitivity, specificity...(Complete abstract eletronic access below)
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Fernandes, Darcy. "Leucoplasia oral e leucoplasia verrucosa proliferativa: um estudo clínico comparativo /." Araraquara, 2015. http://hdl.handle.net/11449/149217.
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Orientador: Elaine Maria Sgavioli Massucato<br>Banca: Jorge Esquiche León<br>Banca: Lays Martin Sobral<br>Resumo: O carcinoma espinocelular (CEC) representa mais de 95% de todas as neoplasias malignas que acometem a cavidade oral e muitas vezes estes tumores são precedidos por alterações clínicas que apresentam um evidente potencial de transformação maligna, as quais são chamadas de desordens potencialmente malignas orais (DPMO). Dentre estas, a leucoplasia oral (LO) é a principal condição dentre as DPMOs com uma taxa de incidência igual a 3,4% e uma taxa de transformação maligna que varia de 0,2% até 17,5%. Uma forma menos reconhecida e ainda pouco compreendida de LO denominada leucoplasia verrucosa proliferativa (LVP), representa uma variante de comportamento persistente e progressivo para malignidade, com uma taxa de transformação maligna ocorrendo em mais de 70% dos casos. O diagnóstico da LVP atualmente só é possível através da observação temporal e individual de cada paciente, com a demonstração de progressão clínica e histológica das lesões para um CEC. A dificuldade no diagnóstico precoce da LVP decorre da sobreposição de características clínicas e histopatológicas, especialmente em casos de LO multifocal convencional. Portanto, foi proposto inicialmente realizar a classificação de casos multifocais de LO encontrados no Serviço de Medicina Bucal da Faculdade de Odontologia de Araraquara - UNESP, durante os anos de 1995 até 2015, segundo descrição da Organização Mundial da Saúde (OMS, 2005) e critérios diagnósticos para LVP atualmente propostos por Cerero-Lapiedra (2010) e Carrard (2013). Posteriormente, foi realizada uma análise comparativa entre as características clínicas e microscópicas de casos de LVP e LO. Os resultados deste estudo revelaram que dentre 86 casos de LO, 45 casos apresentaram o envolvimento de dois ou mais sítios orais configurando estes como casos de LO multifocal. Segundo avaliação realizada por dois observadores experientes...(Resumo completo, clicar acesso eletrônico abaixo)<br>Abstract: The squamous cell carcinoma (SCC) represent more than 95% of all the malignant neoplasia of the oral cavity and most of times these tumors are preceded by clinical conditions that have a potential for malignant transformation called oral potentially malignant disorders (OPMD). Among these, the oral leukoplakia (OL) is the most important OPMD, with an incidence rate of 3.4% and a malignant transformation from 0.2 to 17.5%. A form less recognized and poorly understood of leukoplakia is the proliferative verrucous leukoplakia (PVL) which represents a variant with a persistent and progressive to malignancy behavior, with a malignant transformation ratio up to 70% of cases. Currently, the diagnosis of PVL is only made by the temporal and individual observation of each patient, with the demonstration of clinical and histopathological progression to an SCC. The difficult to stablish an early diagnosis of PVL comes from the overlap of clinical and histopathological features with conventional multifocal OL cases. Therefore, was initially proposed to perform a classification of multifocal OL cases found in the Oral Medicine Service from the Araraquara Dental School - UNESP, between 1995 and 2015, according to the WHO definition (WHO, 2005) and the current suggested diagnostic criteria for PVL by Cerero-Lapiedra (2010) and Carrard (2013). Lately, a comparative analysis was conducted between the clinical and microscopic features from cases of PVL and OL. The results of this study revealed that between 86 cases of OL, 45 presented involvement of two or more setting this as multifocal OL cases. According to the evaluation by two experts, 14/45 were considered true cases of PVL. The classification of the same 45 cases by the WHO definition revealed 21/45 cases as PVL, by the Cerero-Lapiedra 27/45 cases were PVL and 4/45 cases were PVL according to Carrard. Sensitivity, specificity...(Complete abstract eletronic access below)<br>Mestre
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Baldracchini, Francesca. "Protein microarrays for differential diagnosis of infectious diseases." Thesis, Imperial College London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501435.
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Gesler, Toni L. "Differential diagnosis of head injury and depression in adults." Virtual Press, 2005. http://liblink.bsu.edu/uhtbin/catkey/1343468.
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A differential diagnosis between head injury and depression is critical to ensure proper treatment and appropriate interventions. Knowledge about this can only aid counseling psychologists' work with this population and, identifying a measure that can assist in this process is essential. The purpose of this study is to measure the utility of the Dean — Woodcock Neuropsychological Assessment System (D-WNAS) in distinguishing individuals with head injury from those who have a primary diagnosis of depression, and general neurological impairment. Participants included 433 adults (222 males, 211 females) between the ages 20-55 years of age (mean = 35.3 years, SD = 10.97 years) from the Midwestern United States. During the individual's treatment in the neuropsychological laboratory, each person was administered the following: the Dean-Woodcock Structured Interview (Dean & Woodcock, 1999), mental status exam, the Woodcock Johnson — Revised Tests of Cognitive Ability (WJ-R COG; Woodcock & Johnson, 1989b), the Woodcock Johnson — Revised Tests of Achievement (WJ-R ACH; Woodcock & Johnson, 1989a), and the Dean-Woodcock Sensory Motor Battery (DWSMB; Dean & Woodcock, 1999). This study indicates that responses to D-WNAS can be used to reliably classify adults into groups of depression, head injury, and general neuropsychological impairment. In particular, responses to the D-WSMB portion of the D-WNAS can be used to reliably classify adults into groups of depression, head injury, and general neuropsychological impairment. Classification results revealed that the original grouped cases were classified with 62.6 % (p < .001) accuracy and with 73.2% overall accuracy when the head injury and general neurological impairment groups were combined and compared to depression and normative groups. The WJ-R COG and WJ-R ACH were not as reliable as the D-WSMB at predicting group membership.<br>Department of Counseling Psychology and Guidance Services
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Reneker, Jennifer Christine. "Differential Diagnosis of Dizziness Following a Sports-Related Concussion." Kent State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=kent1445530345.
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Costa, Fabiana Manuel. "Diagnóstico e tratamento da leucoplasia proliferativa verrucosa." Master's thesis, [s.n.], 2015. http://hdl.handle.net/10284/5108.
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Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Medicina Dentária<br>Embora a sua incidência seja variada, o cancro da cabeça e do pescoço é responsável por aproximadamente 350 000 mortes por ano em todo o mundo, sendo uma grande preocupação para a saúde pública.
Estes cancros podem ser precedidos por lesões potencialmente malignas, entre as quais se insere a leucoplasia.
A leucoplasia oral foi definida pela OMS como “uma lesão predominantemente branca da mucosa oral que não pode ser caracterizada como qualquer outra lesão definível” (Pindborg et al., 1997; Van der Waal & Axéll, 2002).
Há um tipo de leucoplasia, denominada leucoplasia proliferativa verrucosa (LPV) cujo aspecto clínico inicial é caracterizado pela presença duma lesão branca, homogénea, aparentemente inócua, que desenvolve áreas eritematosas, superfície verrucosa, comportamento agressivo e envolvimento multifocal com o passar do tempo.
Por um lado, este tipo de leucoplasia tem características especiais, tais como a elevada taxa de malignização, que pode atingir 70% dos casos e por outro lado, a elevada taxa de recidiva.
O problema quanto ao diagnóstico destas lesões é que normalmente já é feito tardiamente, numa fase em que as lesões já evoluíram, de forma que o prognóstico se torna menos favorável.
Embora haja tratamento para a LPV, ainda nenhum conseguiu reduzir as recorrências.
Desta forma, considera-se fundamental o diagnóstico precoce para assim identificar pacientes de risco. Although its incidence is not precise, the head and neck cancer is responsible for 350 000 deaths aproximately, per year all around the world, which is a huge concern for public health.
These cancers can be preceeded by lesions highly malignant in which leukoplakia is inserted.
The oral leukoplakia was defined by OMS as being “a mainly white lesion of the oral mucosa that can not be defined as any other lesion.”
There is a type of leukoplakia, called proliferative verrucous (PVL) which at first clinical approach, presents a white homogeneous lesion, apparently innoffensive that develops erythematous and verrucous areas, aggressive behaviour along the time.
On one hand, this type of leukoplakia has special characteristics such as high malignancy rate, which can reach 70% of cases and on the other hand, the high recurrence rate.
As far as it concerns the diagnostic problem of these lesions is that usually done very late, in a stage in which the lesions have already developed in such a way that the prognostic is less favourable.
Nevertheless there is treatment for PVL, none was able to have complete success.
In this way, it is crucial a fast growing diagnosis in order to identify the patients at risk.
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Verhey, Franciscus Rochus Jozef. "Dementia, depression and forgetfulness clinical studies of the early diagnosis and the differential diagnosis of dementia /." Maastricht : Maastricht : Universitaire Pers Maastricht ; University Library, Maastricht University [Host], 1993. http://arno.unimaas.nl/show.cgi?fid=5854.
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Everitt, Alaina. "Differential Scoring Patterns on the Clock Drawing Test: a Comparison of Vascular Dementia and Alzheimer's Dementia." Thesis, University of North Texas, 2006. https://digital.library.unt.edu/ark:/67531/metadc5283/.
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This study examined differences in scoring patterns among those diagnosed with Alzheimer's dementia and vascular dementia on the clock-drawing test. Archival clock drawing data was retrieved on 279 patients presenting at a county hospital-based memory clinic. Analysis of drawings was based on frequency of qualitative errors, as well as an overall quantitative score. Mean comparisons found those patients with Alzheimer's dementia to perform worse on both quantitative and qualitative scoring measures. However, Pearson's chi-squared test revealed a significantly higher rate of spacing errors among subjects with vascular dementia. Such lends support to my hypothesis that impaired executive functioning in vascular dementia patients would lead to poor qualitative performance. Logistic regression found significant predictive ability for the qualitative criteria in diagnosis (χ2 = 25.49, p < .001), particularly the rate of omission (z = 8.96, p = .003) and addition errors (z = 7.58, p = .006). Such findings hold important implications for the use of qualitative criteria in cognitive screening assessments.
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Leung, Kin-sang, and 梁建生. "A rapid molecular testing system for differential diagnosis of myeloproliferative neoplasms." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48334145.
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Myeloproliferative neoplasms include a heterogeneous group of stem cell disorders with overproduction of myeloid cells. They have very different clinical courses and prognosis and are amenable to specific targeted therapy. A prompt and accurate diagnosis is therefore very important. Genetic characterisation plays an important role in diagnosis and classification of these disorders. BCR-ABL1fusion gene and JAK2V617F mutation are the particular major molecular markers to be detected because of availability of targeted therapy.
In this study, a new molecular testing system was developed for the differential diagnosis of myeloproliferative neoplasms. A multiplex reverse-transcriptase polymerase chain reaction was developed for fast detection of JAK2 V617F mutation and BCR-ABL1fusion simultaneously. It was demonstrated to be fast and highly sensitive and specific for the mutations as validated by analysis of clinical samples. The sensitivity limit was well suited for clinical diagnosis. There was great potential saving in consumables and manpower with a much shortened turn-around-time in most cases when compared to conventional diagnostic protocol.<br>published_or_final_version<br>Pathology<br>Master<br>Master of Medical Sciences
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NAGASAKA, TETSURO, TOYOHARU YOKOI, TOYONORI TSUZUKI, et al. "Immunocytochemical Analysis for Differential Diagnosis of Thyroid Lesions Using Liquid-Based Cytology." Nagoya University School of Medicine, 2011. http://hdl.handle.net/2237/14911.
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Taylor, Cindy J. "Development and Validation of the Checklist for Differential Diagnosis of Attentional Problems." Thesis, University of North Texas, 1999. https://digital.library.unt.edu/ark:/67531/metadc279109/.
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The current study discussed the development and validation of the Checklist for Differential Diagnosis of Attentional Problems (CDDAP), a tool for use with adults seeking diagnosis and treatment of an Attention Deficit Hyperactivity Disorder. Normative data are provided on three subject groups (ADHD adults, controls, and adults with other psychiatric disorders). Convergent validity was established with the SCL-90, and criterion validity established through comparing scaled scores with final diagnoses. Overall, this measure was accurate at differentiating adults with ADHD from controls and adults with other psychiatric disorders. Results indicated that the CDDAP was also able to identify other psychiatric disorders with 71 to 92% accuracy, depending on the disorder.
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Tutunji, Maha Sa'di. "Development of analytical methods for the differential diagnosis of exposure to lead." Thesis, Loughborough University, 1988. https://dspace.lboro.ac.uk/2134/10511.
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The modern comprehensive approach in problem solving was adopted in this study to resolve the analytical problems associated with the differential diagnosis of various degrees of exposure to lead. Thorough investigation of all the analytical steps was undertaken starting with the sampling procedure, through the proper choice of the analytical methods for the analysis of indicators of dose and indicators of effect, to the data reduction and evaluation. Reliable, selective and sensitive analytical techniques were developed for the direct analysis of lead, bismuth, antimony and the porphyrin carboxylic acids in body fluids. The sampling step was arbitrarily re-defined on the basis of the lead metabolic model to include two sampling conditions: the non-steady state and the steady state conditions. For diagnostic purposes the results obtained when sampling is done in the non-steady state proved to be more valuable. Analytical results obtained from the steady state condition were also quite revealing. A direct, sensitive, selective and reliable potentiometric stripping analysis method for the trace determination of lead as an indicator of dose in blood,plasma and urine was developed. The various parameters and experimental conditions were investigated. The signals obtained from dearated solutions of the samples using Hg(II) as the oxidant were compared with those obtained from nondearated solutions in which dissolved oxygen acted as the oxidant. The low detection limits of the former method ensured that during the analysis of control specimens in particular, the analyst ',\/ill not be working near the detection limits of the method. Freedom from organic and inorganic interferences coupled with enhancement of the sensitivity due to matrix effects rendered the method particularly useful. By slight modification of the pro- xcedure a wide working range can be attained. Good correlation coefficients bet'ofJeen added and measured Pb(Il) were obtained and method comparison with the thermal ionization stable isotope dilution mass spectrometry and the atomic absorption spectrometry gave a correlation of 0.9999. The adopted PSA in dilute dearated samples of body fluids was adapted for the determination of trace concentrations of Bi(!Il) and Sb(IlI) in body fluids. Slight modifications of the electrolyzing potential using the in situ plating procedure and longer deposition periods were necessary. The results indicated that in subjects highly exposed to lead, high concentrations of Si(lIl) and Sb(III) were detected. An ion pair reversed phase HPLC method coupled with fluorescence detection proved valuable for the analysis of blood and urinary porphyrin carboxylic acids. By optimization of the chromatographic conditions using either the fast RP-C18 Ultrasphere XL-DDS column or the Lichrosorb RP-C2 column and multinear gradient eiution with a mobile phase consisting of methanol/water, both containing 5 mMol/1 tetrabutylammonium phosphate as the counter ion, we were able to detect the earliest biochemical changes that occur in the haem biosynthetic pathway resulting from exposure to lead. The developed method permitted the detection of porphyrins in trace concentrations of 0.2 ng directly in urine samples without tedious sample pretreatment. A wide linear response curve was obtained. The method allows the differential diagnosis of the various diseases that produce derangements in the haem biosynthetic pathway.
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Coclami, Tina. "Psychiatric comorbidity : differential characteristics and outcome amongst single and dual diagnosis psychiatric patients." Thesis, City University London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433436.
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Thomason, Julie Esther-Maree. "Audiological detection and differential diagnosis of proven and suspected retrocochlear pathologies in adults /." [St. Lucia, Qld.], 1999. http://www.library.uq.edu.au/iad/absthe15802.pdf.
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Kendall-Jones, Rowan. "An investigation into the differential diagnosis of autism spectrum disorder and attachment difficulties." Thesis, University of Birmingham, 2014. http://etheses.bham.ac.uk//id/eprint/4812/.
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This study reviews the evidence for commonalities in the behavioural presentation and functioning of children with Autism Spectrum Disorder (ASD) and attachment difficulties. A comparative analysis was conducted to evaluate current practice, assess the scale of misdiagnosis, and identify areas of differential presentation. Teacher-ratings of the frequency of behaviours were collected for two groups of primary school children matched for age, sex and school: one with recent diagnoses of ASD (n = 12) and a control group without diagnoses (n = 12). Three children with ASD diagnoses had higher ratings for attachment difficulties than ASD, at a level approaching significance. However, within-group analysis showed no significant difference between the median ASD and attachment difficulties ratings in the group with ASD diagnoses. A between-group comparison revealed significantly more behaviour suggestive of attachment difficulties in the ASD. Finally, the measure, based on ‘The Coventry Grid’ (Moran, 2010), was found to have acceptable reliability and good face and content validity. However, while the literature suggested good construct validity, analysis of dimensionality raised questions about how we construe the aetiology and mechanisms that constitute the phenomenology that informs the diagnosis of ASD and attachment difficulties. Implications for the ASD diagnostic process are discussed.
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Berglof, Hollie K. "Differential Diagnosis of Attention Deficit Hyperactivity Disorder and Depression: Potential Bias and Misdiagnosis." DigitalCommons@USU, 2003. https://digitalcommons.usu.edu/etd/6189.
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This study investigated whether psychologists are attempting to distinguish between attention deficit hyperactivity disorder (ADHD) and depression in youth. Findings indicate that, overall, clinicians are conducting comprehensive evaluations and considering ADHD and depression as likely diagnoses. Clinicians were more likely to use self-report depression measures if the client was female or adolescent than if the child was male or school age; however, they were equally likely to incorporate ADHD-related measures with males and females , and 8 year olds and 15 year olds . Clinicians were more likely to consider adolescents than school-age children and females than males to have a mood disorder. Doctoral-level clinicians were more likely to consider a mood disorder and ADHD than master's- level clinicians. Clinicians who had completed a child psychopathology course were more likely to consider ADHD than those who had not completed such a course. The implications of these findings for child-oriented clinicians are discussed.
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George, Carrie Anne. "Development and assessment issues in the diagnosis of early-onset bipolar disorder." Texas A&M University, 2004. http://hdl.handle.net/1969.1/2800.
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Psychologists face challenges on a daily basis. Among the challenges they face are making diagnostic decisions. Recently, bipolar disorder has shown an increase in diagnosis in children and adolescents. Once felt to be an adult disorder, journals are describing the use of the diagnosis with children and adolescents. While the diagnosis has been considered as relevant, no psychological measures have been developed to
make an accurate diagnosis. Developing a new psychological measure for bipolar disorder in children is critical. Due to the lack of data on what constitutes normal behavior as well as the absence of an accurate measurement of early-onset bipolar disorder, it is necessary to develop such a measure. The purpose of this study was to evaluate a newly developed measure based on the literature on bipolar disorder in
children. The measure was developed through a review of the current literature, DSMIV-TR criteria for bipolar disorder, and ideas developed within a bipolar disorder research team at Texas A&M University. Because of the item content, the new measure is entitled the Mania Assessment Scale for Children (MASC). The first steps in understanding a new measure for early-onset bipolar disorder is to determine the factor structure of the scale as well as the reliability and validity. Results indicated that the MASC is best understood as a measure with a single score, or factor. Once the underlying structure of the MASC was determined, the study evaluated which behaviors of typically developing children may be misconstrued as indicative of bipolar disorder. Group differences on the measure are also evaluated. Results from statistical analysis showed that there were significant group differences between age groups, but not gender and ethnic groups. In addition, there was a statistically significant difference between clinical and non-clinical groups. To conclude, a discussion of the findings and recommendations for future research is presented. Overall, it is hoped that the study will help psychologists better understand the complexity of behaviors associated with the
diagnosis of bipolar disorder in children and adolescents.
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Stubbs, Peter John. "Cardiac Troponin T and myocardial damage." Thesis, University College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309504.
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Noggle, Chad A. "Differential diagnosis of Alzheimer dementia and depression using the Dean-Woodcock Neuropsychological Assessment System." Virtual Press, 2006. http://liblink.bsu.edu/uhtbin/catkey/1344193.
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This study investigated the utility of the cognitive measures of the Dean-Woodcock Neuropsychological Assessment System (D-WNAS) in the differential diagnosis of Alzheimer dementia (AD) from depression. Past research has found an overlap of symptoms in the early stages of AD and those found in geriatric depression. In both instances, patients are likely to report memory loss, attention deficits, and mood disturbances. As a result of this similarity, differentially diagnosing one from another is a vexing problem for the clinical practitioner. Although a number of screening measures have been offered, none have proven to be clinically useful. Some have proposed this is the result of reliance upon use of single-factor measures. Indeed, many have proposed a multiple factor assessment model would be of more utility in diagnosing AD and depression. Considering the importance of an accurate diagnosis in treatment, this study utilized a multiple factor cognitive model offered by the Dean-Woodcock Neuropsychological Assessment System to differentiate AD from depression.Specifically, subtest scores of the Woodcock-Johnson III - Tests of Cognitive Ability (WJ-III; cognitive measure of the Dean-Woodcock Neuropsychological Assessment System) were compared. Participants (n = 172) fell into one of three groups (i.e. Depressed, Demented, or Normal) based on the diagnoses of a board certified neurologist and neuropsychologist. Results showed clinical groups performed more poorly than normal participants on tests of the WJ-III. In addition, AD participants differed significantly from depressed participants on the Visual Matching and Spatial Relations tests of the WJ-III. However, in all, the WJ-III demonstrated a classification hit rate of less than 70%. Although groups were found to differ in specific ways, the classification hit rate of the WJ-III suggested it could not differentially diagnose AD from depression alone.<br>Department of Educational Psychology
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Kaiser, Sylvie. "Radiologic diagnosis of appendicitis in children /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-813-0/.
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Dickinson, Scott Arthur. "The development of a portable recording spirometer for the differential diagnosis of occupational asthma." Thesis, Staffordshire University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239939.
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Davis, Kathleen Marg. "Differential diagnosis of oppositional defiant and conduct disorder utilizing the Millon Adolescent Clinical Inventory." Virtual Press, 2007. http://liblink.bsu.edu/uhtbin/catkey/1370878.
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Studying disruptive behavior disorders in adolescents is critical; however, there is a paucity of literature on methods for differentially diagnosing the two main disruptive behavior disorders: Oppositional Defiant Disorder and Conduct Disorder. Conduct Disorder is defined as a persistent pattern of behavior where the basic rights of others or other major social norms are violated whereas Oppositional Defiant Disorder is usually diagnosed in childhood or adolescence, and is defined by a pattern of disobedient, hostile, or defiant behavior towards authority figures. Despite some similarities in presentation, the majority of research supports the notion that these two disorders are distinct. Finding accurate ways to differentiate these two disorders is important for discovering and implementing empirically validated treatments. The primary purpose of this study was to determine how the Millon Adolescent Clinical Inventory, a commonly used self-report scale, distinguished between adolescents presenting with either Oppositional Defiant or Conduct Disorder who had been admitted to a residential treatment facility. A secondary component of the current study examined gender differences in the two disorders.Multivariate Analysis of Variance was used to determine if the two diagnostic or gender groups were significantly different. If so, discriminant function analysis was employed to determine where the difference occurred. Although some scales approached significance, there were no statistical differences among adolescents with Conduct Disorder and Oppositional Defiant Disorder across any of the dependent variables. There were, however, gender and age differences found across several scales. Unfortunately, because there were no interactions with diagnosis on any scales, differences occurred equally among adolescents from either diagnostic group. This result raises questions as to whether the Millon Adolescent Clinical Inventory is a useful diagnostic instrument for disruptive behavior disorders. This instrument may be more useful to determine individual characteristics that would impact treatment than as an instrument for researchers studying empirically validated interventions for Conduct Disorder and Oppositional Defiant Disorder.<br>Department of Educational Psychology
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Amer, Hani Taha Sherif Ben. "Differential diagnosis of parkinsonism and tremor disorders : basal ganglia imaging with a novel isotope." Thesis, University of Glasgow, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312132.
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Bauder, Jennifer M. "Porotic hyperostosis differential diagnosis and implications for subadult survivorship in prehistoric west-central Illinois /." Diss., Online access via UMI:, 2009.
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Sullivan, Donna L. "Temporality of Risk Factors and the Gender Differential Related to Autism Spectrum Disorder Diagnosis." ScholarWorks, 2015. https://scholarworks.waldenu.edu/dissertations/275.
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Autism spectrum disorders (ASD) constitute life-long neurodevelopmental conditions. Globally, ASD risk for males remains 2 to 4 times greater than for females. Critical exposure mechanisms, their timing on ASD risk, and associations with the ASD gender differential remain elusive. The purpose of this study was to describe the relationship between preconception, pregnancy, recalled lactation practice, and infant traits, on ASD risk and the gender differential of ASD. A recently published temporal framework was adapted to study effects of maternal smoking and vitamin use, and recalled lactation practice on offspring ASD diagnosis with adjustment for preconception health and infant breathing traits. A retrospective case-control analysis using 733 child data records from U.S. autism registry characterized child gender-stratified relationships of 9 study variables. Logistic regression results showed prior maternal smoking, male gender, and maternal recollection of lactation practices were associated with offspring ASD diagnosis. Exposure factors associated with ASD did not differ by child gender or maternal vitamin use. Infant respiratory distress at birth was a covariate and collinearly related to obstetric risks. Maternal smoking was antecedent to respiratory distress and lactation practice. Study limitations included incomplete responses without repeated measures for recalled lactation practice and maternal diet variables. The implications for positive social change include a better understanding of reproductive, preconception, and prenatal risk factors of ASD. The study results have implications for reproductive health, smoking cessation programs, family planning, and prenatal care for women of reproductive age.
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Assi, Jolnar Abdulkarim. "Knightian uncertainty modelling and its impact on option pricing : applications of fuzzy set theory, fuzzy measure theory and fuzzy differential calculus." Thesis, City University London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.274460.
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Juechter, Julia I. "Differential Diagnosis of Autism Spectrum Disorders Using the BASC-2 Parent Rating Scales Preschool Form." Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/cps_diss/84.
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The Behavior Assessment System for Children, Second Edition (BASC-2; Reynolds & Kamphaus 2004) is a behavior rating scale commonly used in preschool settings. In addition to measuring behavioral constructs such as hyperactivity, social skills, and adaptive functioning, the BASC-2 includes a Developmental Social Disorders (DSD) content scale that evaluates the presence of behaviors commonly associated with pervasive developmental disorders, including items related to self-stimulation, withdrawal and poor socialization. This study compared the T-scores of toddler and preschool-aged children diagnosed with an autism spectrum disorder (ASD) to children diagnosed with other developmental delays, and typically developing children using the BASC-2 Parent Rating Scales, Preschool form. Participants from the ASD group obtained significantly higher T-scores than the typically developing group on the Hyperactivity, Atypicality, Withdrawal, and Attention Problems scales, and obtained significantly lower T-scores on the Adaptability, Social Skills, Activities of Daily Living, and and Functional Communication scales. Significant differences were not observed between participants in the ASD group and those diagnosed with other developmental delays. However, the DSD scale was effective in distinguishing between groups, with participants in the ASD group obtaining significantly higher T-scores on the DSD scale than those diagnosed with other developmental delays and typically developing children.
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Pearce, Wendy Maureen, and wendy pearce@jcu edu au. "The Role of Morphosyntax and Oral Narrative in the Differential Diagnosis of Specific Language Impairment." Flinders University. Medicine (Dept of Speech Pathology & Audiology), 2007. http://catalogue.flinders.edu.au./local/adt/public/adt-SFU20070220.174901.
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Against the background of a broad range of language features that are identified as characteristic of specific language impairment (SLI), some researchers have identified a narrower set of clinical markers considered the hallmark of SLI. However, comparisons with language impairments that fall outside the criteria for SLI are limited. This thesis is concerned with determining which language features, if any, are capable of differentiating children with SLI from children with non-specific language impairment (NLI).
Conversation and oral narrative language samples were collected from seventy five children aged 2 ½ to 6 years comprising four research groups: 21 participants with SLI, 13 participants with NLI, 21 age-matched participants with normally developing language (AM) and 20 younger language-matched participants with normally developing language (LM). Matching for group comparisons required that the SLI and NLI groups had similar levels of language ability on a standardised assessment and mean length of utterance (MLU), which reduced the SLI group to 15 participants for these comparisons. The LM group was also matched to the SLI and NLI groups on MLU. A wide range of language variables from the conversation and narrative samples were analysed, covering the domains of general sample measures, morphosyntactic accuracy and complexity, narrative structure and cohesion.
The SLI and NLI groups performed similarly in all domains and could not be differentiated diagnostically on the measures examined. The most consistent group effects were for comparisons between the AM and LM groups, which demonstrated the effects of maturation and development. The language impairment (LI) and LM groups could not be differentiated on the majority of general language sample or morphosyntactic measures but the SLI group produced narratives that were structurally more complex and cohesive than the LM group.
Language tasks varied in their effectiveness in differentiating groups. More consistent group effects for the grammatical accuracy measures were obtained from the conversations than the narratives, and from composite measures compared to individual morpheme measures. Targeted elicitation tasks were more effective than the conversations or narratives in producing consistent group effects for accuracy of individual verb tense morphemes. More consistent group effects for the narrative features were obtained from a wordless picture book than a single scene picture. A set of discriminant function analyses showed that LI was most effectively identified using a combination of key morphosyntactic measures from the conversations and key narrative feature measures from the two narratives.
The results have implications for diagnostic practices, intervention practices and theoretical constructs and explanations of SLI and NLI. In particular, a broad, holistic view of LI is supported, as an impairment that impacts on all domains of language which interact with each other and must be considered collectively, rather than as individual, splintered skills.
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Thomas, Saralene Iona. "Genetic markers in the differential diagnosis in a family setting of episodic loss of consciousness." Thesis, Stellenbosch : Stellenbosch University, 2000. http://hdl.handle.net/10019.1/51777.
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Mitchell, K. W. "The visual evoked potential in the differential diagnosis of occular hypertension and chronic simple glaucoma." Thesis, University of Newcastle Upon Tyne, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.374770.
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Chaisi, Mamohale E. "Diversity of Theileria parasites in African buffalo (Syncerus caffer) and the challenge of differential diagnosis." Thesis, University of Pretoria, 2012. http://hdl.handle.net/2263/31238.
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In South Africa, the diagnosis of Theileria parva in cattle and buffalo has been complicated by the presence of mildly pathogenic and non-pathogenic Theileria spp. This can lead to inaccurate diagnostic results and confuse the epidemiology of theileriosis. The aims of this study were to identify and characterize the 18S rRNA genes of novel Theileria spp. of the African buffalo, as well as to test new gene targets that will allow for the development of more accurate diagnostic tests for the identification of T. parvainfections in cattle and buffalo. Buffalo blood samples originating from different geographical regions in South Africa and from Mozambique were screened for the presence of Theileria spp. by the reverse line blot (RLB) hybridization assay. A total of six Theileria spp., namely T. parva, Theileria sp. (buffalo), Theileria mutans, Theileria velifera and Theileria buffeli, were identified from the buffalo samples. These occurred mainly as mixed infections. Some of the samples hybridized only with the Theileria/Babesia genus specific probe that is used in the RLB assay, and not with any of the species-specific probes used, suggesting the presence of novel genotypes or species. The full-length 18S rRNA genes of parasites from selected samples were characterized by cloning and sequencing. In addition to the identification of 18S rRNA gene sequences that were similar to published Theileria spp. of cattle and buffalo, we identified Theileria sp. (bougasvlei), and novel 18S rRNA gene variants of T. mutans, T. velifera, T. bufJeli. This variation explained why the RLB hybridization assay failed to detect these species in some of the analysed samples. As extensive variation was observed within the T. mutan group, specific RLB oligonucleotide probes were designed from the V 4 hypervariable region of the T. mutans-like 1 and 2/3 18S rRNA gene sequences. Unfortunately these cross-hybridized with T. mutans target DNA and could not be used to screen buffalo samples to determine the occurrence of these genotypes in buffalo in South Africa. This problem could be solved by designing probes from a more variable area of the 18S rRNA gene of the T. mutans groups. Alternatively, a quantitative real-time PCR (qPCR) assay could be used for differentiation of these genotypes as it is more sensitive than the RLB assay. Despite the variation observed in the full-length T parva 18S rRNA gene sequences, the area in the V 4 hypervariable region where the T parva RLB and real-time PCR hybridization probes were developed was relatively conserved between sequences obtained in this study. The existing T parva-specific qPCR assay was able to successfully detect all T parva variants identified in this study and, although amplicons were obtained from Theileria sp. (buffalo) and Theileria sp. (bougasvlei) DNA, these species were not detected by the T parva-specific hybridization probes. The sequences of the other Theileria spp. and the novel genotypes identified in this study under the probes were also different from that of T parva and therefore these species do not compromise the specificity of the T parva 18S qPCR assay. In order to determine the sequence variation and phylogenetic positions of T buffeli spp. of the African buffalo, we cloned and sequenced their 18S rRNA gene and complete internal transcribed spacer (ITS). We identified novel T buffeli-like and T sinensis-like 18S rRNA and ITS genotypes from buffalo originating from two different geographical regions in South Africa. There was extensive sequence variation between these novel South African genotypes and known T buffeli-like and T sinensis-like genotypes. The presence of organisms with T buffeli-like and T. sinensis-like genotypes in the African buffalo is of significant importance, particularly to the cattle industry in South Africa as these animals might act as sources of infections to naIve cattle. Recently, a qPCR assay based on the cox III gene was developed for the diagnosis of Theileria spp. in cattle. This test detects and differentiates six Theileria spp. in cattle. We evaluated the use of this assay for the detection of Theileria spp. in buffalo. The results of the cox III qPCR were compared to those of the RLB and 18S qPCR for the simultaneous detection and differentiation of Theileria spp. of the African buffalo, and for the specific detection of T parva, respectively. The cox III genes from selected samples with non-specific melting peaks were characterized by cloning and sequencing. Extensive sequence variation in the cox III gene was observed between and within species. The T mutans group was the most variable. The qPCR assay could be further improved by designing new primers and probes using all known cox III gene sequences of Theileria spp. Of buffalo and cattle. This study highlights the complexity of the diagnosis of T parva in cattle and buffalo in South Africa. It provides invaluable information towards the development of an improved molecular diagnostic assay for T parva and co-infecting species in cattle and buffalo in South Africa which will assist the veterinary regulatory authorities in the control of Corridor disease in South Africa.<br>Thesis (PhD)--University of Pretoria, 2011.<br>Veterinary Tropical Diseases<br>Unrestricted
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Geller, Norman J. "Asperger's Syndrome and Non-verbal Learning Disabilities: A study of differential diagnosis agreement across disciplines." VCU Scholars Compass, 2005. http://scholarscompass.vcu.edu/etd/1373.
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Mental health professionals tend to have a clinical perspective that is dependent upon Diagnostic and Statistical Manual of Mental Disorders-IV-TR (DSM-IV) criteria for a differential diagnosis. School-based clinicians are bound by regulations governing special education placement established by Individuals with Disabilities Education Act (IDEA). While both sets of clinicians generate diagnostic recommendations for students, the guidelines and criteria are not of parallel descriptors. AS is only a diagnosis provided for in DSM-IV. Non-verbal learning disability (NVLD) and high functioning autism (HFA) are addressed in both DSM-IV and IDEA. The dilemma presented to clinicians is intertwining the terminology of both fields in order to provide a more concise and meaningful diagnosis for the students who are being served. Although school-based and mental-health clinicians provide services for students, the criteria employed may differ. Essentially, the descriptors that are applied to Asperger's Syndrome (AS) and NVLD are similar and may only differ in the criteria used by different discipline affiliations. Upon review of the literature, there seems to be some question about the different clinical perspectives and diagnosis that may emerge. The criteria used for disability identification is often based upon discipline affiliation. Bashe and Kirby (2000) suggest that psychiatrists may identify students with AS while an education-based organization might suggest a learning disability and yet, a speech and language pathologist might refer to the same set of characteristics as a semantic-pragmatic disorder or an audiologist would refer to a central auditory processing disorder. Furthermore, Bashe and Kirby felt that the "specialist" generally sees and identifies the facet of AS that pertains to their area of expertise. While identification is a critical component of planning intervention, service delivery of both AS and NVLD students are relegated to educators and the school-based program. Therefore, the terminology employed to identify a disability must be applicable to the school setting. The literature often refers to AS in a hyphenated context with HFA. Rather than there being a consistent diagnostic category of AS, AS is often joined with HFA as a means of describing symptoms that transcend characteristics of autism but still have similarities with students classified as having autism. There is also a considerable amount of literature that differentiates the two terms and refers to AS and HFA as two distinct disabilities. Furthermore, there is a great deal of conjecture regarding AS as a type of learning disability. This study will ascertain whether there is agreement between disciplines in diagnosis of AS and NVLD, whether or not there is consistency between and among disciplines regarding the importance of specific characteristics of the two disabilities, and the application of these characteristics when rendering a diagnosis and intervention recommendations. While the results of this study did not demonstrate an interaction between diagnosis and professional discipline affiliation, it did demonstrate that the rate of correct diagnosis for AS was significantly higher than that of NVLD and autism. An alternative conclusion is that AS is overly diagnosed and impacting the rate of correct diagnosis for NVLD and autism. While there was an association between the elements used for clinical diagnosis of both autism and AS, there was a demonstrable correlation of service delivery models for both NVLD and AS and a departure of similarities in service delivery between AS and autism. Implications of these results are discussed in greater detail.
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Gonzalez, Christine. "Posttraumatic Stress Disorder as a Differential Diagnosis of Sexually Abused Children: a Survey of Psychologists." Thesis, University of North Texas, 1997. https://digital.library.unt.edu/ark:/67531/metadc278632/.
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Psychologists' diagnostic choices when the specificity of child sexual abuse in a
clinical vignette is varied was examined. The degree to which Posttraumatic Stress Disorder (PTSD) was judged to be a viable diagnostic choice among a set of diagnoses was analyzed under conditions with sexual abuse stated, implied, not stated, and excluded. PTSD was rated as more likely for the stated and implied sexual abuse vignettes than for the not stated and excluded vignettes.
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Perry, Richard James. "Attention and executive function in the differential diagnosis of Alzheimer's disease and other cortical dementias." Thesis, Imperial College London, 2005. http://hdl.handle.net/10044/1/8825.
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Semler, Caroline Joy. "The differential role of the SSI with normal preschool children." PDXScholar, 1987. https://pdxscholar.library.pdx.edu/open_access_etds/3732.
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The purpose of this study was to investigate the disfluency characteristics of normal 33-39 month old children in order to determine the differential role of the SSI with young children. The following questions were answered:
1. What are the types and frequencies of disfluencies demonstrated by normal 33-39 month old children?
2. How do the scores of normal 33-39 month old children distribute on the Stuttering Severity Instrument?
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Platt, Suzanne. "How do people with a mental health diagnosis construct an identity?" Thesis, Canterbury Christ Church University, 2016. http://create.canterbury.ac.uk/14909/.
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Psychiatric diagnosis is used to categorise and treat mental health problems in the UK yet is widely criticised for struggling to convincingly categorise the experience of distress and that it is socially constructed from the culmination of historical and cultural interactions. Service-user accounts are varied and there is a paucity of qualitative research that considers the positive and negative effects of labelling. To understand identity construction in the context of a psychiatric diagnosis, the present study recruited 16 participants from a service-user research group and five focus groups were conducted. Transcripts were studied using Foucauldian Discourse Analysis. Two major identities were detected ‘illness identity’ and ‘recovery identity’. Participants drew on multiple and competing discourses and which placed them in the position of patient and/or survivor. Medical discourses were dominant throughout the focus groups and were used in a way to convey the fluidity of the identity and how they related to their diagnosis. The study’s limitations are discussed, together with implications for clinical practice and future research.
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Chhaganlal, Kajal [Verfasser], and Florian [Akademischer Betreuer] Heinen. "Diagnosis and differential diagnosis of meningitis at patient's bed side using urine reagent strip to evaluate cerebro spinal fluid / Kajal Chhaganlal. Betreuer: Florian Heinen." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2014. http://d-nb.info/109451702X/34.
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Aguirre-Beltran, Aura Georgina. "Standardisation and evaluation of differential diagnostic systems for the detection of Entamoeba histolytica and Entamoeba dispar." Thesis, London School of Hygiene and Tropical Medicine (University of London), 1999. http://researchonline.lshtm.ac.uk/682278/.
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Entamoeba histolytica is an invasive intestinal amoeba morphologically indistinguishable from Entamoeba dispar, a closely related organism that is not able to invade tissues. Differential diagnosis under conventional microscopy is therefore impossible. Reliable tools are needed for clinical diagnosis and for the reevaluation of the prevalence of infection with the invasive species worldwide. Monoclonal Antibody (MAb) 20/7D exhibited promising results when ascites was used to identify cultured isolates of E. histolytica by indirect immunofluorescence assays (IFA), and when used in a Faecal Antigen Capture Enzyme-Linked Immunosorbent Assay (FAC-ELISA) for laboratory diagnosis of amoebic dysentery and colitis. Here, further development of the assay was attempted to increase its sensitivity and use it for detection of asymptomatic carriers of E. histolytica. After purification and subsequent titration in ELISA, MAb 20/7D did not adequately distinguish between crude lysates of cultured E. histolytica and E. dispar trophozoites. MAb 20/7D reacted with a similar soluble antigen of E. histolytica and E. dispar, which confirmed previous observations in western blot analysis under non-reducing conditions. Therefore, the use of the FAC-ELISA for diagnosis in areas where E. dispar is endemic is probably not viable. A nucleic acid detection method was therefore developed. Polymerase Chain Reaction was used to amplify specific tandem sequences in the 24.5 Kb episome of E. histolytica and E. dispar. After PCR, internal sequences of digoxigenin-labelled PCR products were hybridized to specific biotin-labelled probes for E. histolytica or E. dispar and detected in Enzyme- Linked Immunosorbent Assay (ELISA). The Polymerase Chain Reaction Solution- Hybridisation Immunosorbent Assay (PCR-SHELA) was evaluated on samples from travellers returning from the tropics to Barcelona. The sensitivity and specificity were 98% and 100% respectively, when results were compared with microscopy. PCR-SHELA was also useful for differential diagnosis in cases of amoebic abscesses, amoebic dysentery, salmonellosis, ulcerative colitis and in asymptomatic carriage of E. histolytica. The new test gives sensitive and specific differentiation between E. histolytica and E. dispar in clinical specimens and it has proved successful in screening faecal samples in endemic areas for epidemiological purposes.
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Simuunza, Martin Chitolongo. "Differential diagnosis of tick-borne diseases and population genetic analysis of Babesia bovis and Babesia bigemina." Thesis, University of Glasgow, 2009. http://theses.gla.ac.uk/1240/.
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Abstract: Tick-borne diseases are a constraint to livestock production in many developing countries. They are responsible for high morbidity and mortality resulting in decreased production of meat, milk and other livestock by-products. The most important tick-borne diseases of livestock in sub-Saharan Africa are East coast fever (caused by Theileria parva), babesiosis (caused by Babesia bigemina and Ba. bovis), anaplasmosis (caused by Anaplasma marginale) and heartwater (caused by Ehrlichia ruminantium). Despite their economic importance, information on the epidemiology of these diseases in many countries is often lacking or inadequate, resulting in inappropriate disease control strategies being implemented. The availability of specific, sensitive and cost-effective diagnostic methods is important in the design and implementation of effective disease control strategies. In this study PCR assays based on the 18S and 16S rRNA gene sequences, that could identify Theileria / Babesia and Anaplasma / Ehrlichia pathogens of cattle respectively, were developed. In addition, PCR assays based on the β-tubulin gene that could detect T. parva, Ba. bigemina, Ba. bovis and T. taurotragi, and PCR assays based on the cytochrome b gene that could diagnose infection by Ba. bigemina and Ba. bovis were also developed. When the 18S and 16S rRNA gene PCR assays were combined into a multiplex PCR assay, Ba. bigemina and E. ruminantium DNA did not amplify and some non-specific bands were observed following agarose gel electrophoresis. The β-tubulin gene multiplex PCR assay for the diagnosis of T. parva, Ba. bovis and Ba. bigemina worked relatively well when used on laboratory-derived parasite DNA preparations. However, when it was used on field samples collected on FTA cards, multiple non-specific bands were observed after agarose gel electrophoresis of the PCR products. The 18S and 16S rRNA gene PCR assays were used for an epidemiological study of tick-borne diseases of cattle in Central and Eastern Zambia in the wet and dry seasons. All the disease pathogens under study (T. parva, T. mutans, T. taurotragi, Ba. bovis, Ba. bigemina, Anaplasma spp and E. ruminantium) were prevalent in all the regions of the country in both seasons. However, variation was observed in the prevalence of these pathogens between the regions and the seasons. A number of risk factors, associated with the occurrence of tick-borne pathogens in cattle and the tick burdens observed on cattle in the wet season were determined. A negative association was observed between the number of co-infecting pathogens and the erythrocyte packed cell volume (PCV) of carrier cattle. Using recently available genome sequences, mini- and microsatellite markers were developed for population genetic analysis of Ba. bovis and Ba. bigemina parasite populations. Ba. bovis isolates from Zambia and Turkey and Ba. bigemina isolates from Zambia were used in the population genetic analysis. High levels of genetic diversity were observed for both parasites. Population genetic analysis of the Zambian and Turkish Ba. bovis populations, using eight genetic markers showed that the two populations were sub-structured. The Zambian population comprised a single randomly mating population, while the Turkish population comprised two genetically distinct subpopulations. Population genetic analysis of the Ba. bigemina parasites from Zambia showed that this parasite population was in linkage disequilibrium. Further, analysis of the Ba. bigemina population using STRUCTURE showed that it was genetically sub-structured into five distinct subgroups. However, the resulting sample size of each subgroup was too small to definitely determine whether they were panmictic. These results provide an improved understanding of the epidemiology of bovine Babesia parasites in Turkey and Zambia.
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Silier, Colen Cooper Gore [Verfasser], and Annette [Akademischer Betreuer] Jansson. "Nonbacterial osteitis : a relevant differential diagnosis to bacterial osteomyelitis / Colen Cooper Gore Silier ; Betreuer: Annette Jansson." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2019. http://d-nb.info/1201274672/34.
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Hunter, Randee L. "Bioarchaeological Implications of a Differential Diagnosis of Diffuse Idiopathic Skeletal Hyperostosis (DISH) in Gorilla gorilla gorilla." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1275077374.
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Anderson, James Valentine. "Comparative study of an antioxidant defense mechanism in genotypes of eastern white pine which show differential foliar characteristics." Diss., This resource online, 1990. http://scholar.lib.vt.edu/theses/available/etd-09162005-115019/.
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Oliveira, Augusto CÃsar AragÃo. "IdentificaÃÃo etiolÃgica de quadros dengue-sÃmile no CearÃ, no ando de 2008." Universidade Federal do CearÃ, 2011. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=6580.
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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>A dengue à a arbovirose mais importante no mundo, causando mais de 100 milhÃes de casos de dengue clÃssico (DC) e mais de 250 mil casos de febre hemorrÃgica da dengue (FHD), anualmente. A infecÃÃo com o vÃrus dengue (DENV), famÃlia Flaviviridae, causa um amplo espectro de manifestaÃÃes clÃnicas que variam desde formas assintomÃticas a quadros graves, potencialmente fatais, como os casos hemorrÃgicos e/ou de choque hipovolÃmico. Na maioria das vezes, a doenÃa se apresenta com sintomas inespecÃficos. Dessa forma, torna-se difÃcil diferenciar a dengue de outros casos febris de natureza infecciosa como leptospirose, febre amarela e outras arboviroses, apenas com base nas manifestaÃÃes clÃnicas iniciais. Diante disso, o objetivo deste estudo foi identificar a etiologia de 82 pacientes com quadro clÃnico semelhante ao de dengue e com resultado negativo no isolamento viral (IV) para o DENV. O IV foi realizado pelo LaboratÃrio Central de SaÃde PÃblica do Cearà (LACEN-CE), em 2008. Neste estudo, as amostras desses pacientes foram avaliadas para dengue por meio da detecÃÃo de anticorpos especÃficos contra o vÃrus pela tÃcnica de IgM-ELISA (PanBio DiagnosticsÂ) e pela reaÃÃo em cadeia da polimerase apÃs transcriÃÃo reversa (RT-PCR). As amostras negativas para dengue foram testadas para a detecÃÃo de anticorpos IgM especÃficos contra bactÃrias do gÃnero Leptospira por ELISA (PanBio DiagnosticsÂ). Foram testadas tambÃm amostras de 73 pacientes quanto a infecÃÃo por hantavirus, atravÃs da detecÃÃo de anticorpos especÃficos (IgM e IgG) contra antÃgenos de hantavÃrus e RT-PCR. Trinta e cinco pacientes (35/82; 42,68%) foram positivos para dengue, sendo que destes, todos foram positivos no IgM-ELISA e 4 foram positivos tambÃm no RT-PCR. Das 47 amostras dengue-negativas, apenas 43 foram testadas para infecÃÃo por Leptospira devido ao volume insuficiente das amostras. Seis pacientes (6/82; 7,32%) foram positivos IgM-ELISA para leptospirose. TrÃs pacientes foram positivos para hantavÃrus, entretanto apenas 1 (1/82; 1,22%) foi positivo no IgM-ELISA e 2, no IgG-ELISA. A infecÃÃo dos 35 (42,68%) pacientes negativos em todos os testes de detecÃÃo de infecÃÃo aguda foi classficada como sÃndrome febril indiferenciada (SFI). Esta à a primeira evidÃncia de infecÃÃo por hantavÃrus no Estado do CearÃ. Essas doenÃas podem causar infecÃÃo clinicamente indistinguÃvel da dengue e, portanto, deveriam ser incluÃdas no diagnÃstico diferencial no contexto dessas sÃndromes febris.<br>Dengue is the most important arborvirosis in the world, causing approximately 100 millions cases of classical dengue fever (DF) and more than 250.000 of dengue hemorrhagic fever (DHF), annually. The dengue virus (DENV) belongs to the Flaviviridae family and its infection causes a wide clinical spectrum ranging from assymptomatic forms to severe manifestations, potentially fatal, as in hemorrhagic forms or dengue shock syndrome (DSS). Most of times the disease presents inespecific symptoms. Thus, DF is difficult to distinguish from other acute febrile illnesses, including arboviral ones and leptospirosis, based only on clinical criteria. Given this, the aim of this study was to identify the etiology of 82 patients with clinical picture of dengue-like illness, negative in DENV isolation. The virus isolation was done in Laboratorio Central de SaÃde PÃblica do Cearà (LACEN-CE), Brazil, in 2008. In the present study, the serum samples from these patients were evaluated for dengue infection by IgM-ELISA (PanBio DiagnosticsÂ) and RT-PCR, following Lanciotti et alli protocol (1992). Negative samples to dengue infection were tested to leptospirosis by IgM-ELISA (PanBio DiagnosticsÂ). Seventy-three patients were also tested for hantavirus infection by IgM and IgG by ELISA and RT-PCR. Dengue infection was diagnosed in 35 patients (35/82; 42.68%) of which all were positive in IgM-ELISA, and 4 were also positive in RT-PCR. Of 47 (47/82; 57.32%) DENV-negative samples, only 43 were tested to evaluate lesptospiral infection because of insufficient sample volume. Six patients (6/82; 7,32%) were positive to leptospirosis in the IgM-ELISA. Three patients were positives to hantavirus infection, but only 1 (1/82; 1,22%) was positive in the IgM-ELISA and the two others, in the IgG-ELISA. Thirty and five patients (35/82; 42,68%) remained negative em all tests. They were classified as having other febril illness (OFI). To the best of our knowledge, this is the first evidence of hantavirus infection in humans in the state of CearÃ, Brazil. These diseases, including leptospirosis, may cause infection clinically indistinguishable from DF and therefore should be included in the differential diagnosis of febrile illnesses in this setting.
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Marino, Meghan J. "Monogenic Diseases Masquerading as Multiple Sclerosis: A Systematic Review." Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1296249495.
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Allen, Matthew S. "Seraphs Or Snakes: Consciousness Transformations in a Normal Sample, and Implications for Differential Diagnosis in “Spiritual Emergency”." Connect to this document online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=miami1090266509.
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Thesis (M.A.)--Miami University, Dept. of Psychology, 2004.<br>Title from first page of PDF document. Document formatted into pages; contains [1], iii, 54 p. Includes bibliographical references (p. 33-37).
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Gelder, Barbara C. "The efficacy of a neuropsychological symptom inventory in the differential diagnosis of medical, psychiatric, and malingering patients." Virtual Press, 1999. http://liblink.bsu.edu/uhtbin/catkey/1159140.
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Neuropsychologists are increasingly asked to determine whether a patient may be malingering symptoms of a mild closed head injury. This issue is particularly salient within the context of civil litigation and the potential of significant financial awards. Patients' performances on neuropsychological tests have historically been assumed to accurately reflect their abilities and deficits. Optimal motivation and performance cannot be automatically assumed within the context of litigation. Moreover, comorbid anxiety and depression are frequently present in head injury patients and adversely affect the patient's performance.The frequent comorbidity of psychiatric and medical symptoms complicates interpretation of a patient's neuropsychological evaluation whether or not the patient is involved in litigation. This comorbidity may result in an inaccurate diagnosis, thus delaying treatment potentially causing greater harm to the patient.The present study was conducted to expand previous research that discriminated between simulated malingered and neurological patient responses to a neuropsychological self-report inventory. Additionally, the study investigated the, utility of the Neuropsychological Symptom Inventory in discriminating between simulated medical, psychiatric and malingered patient responses. Results indicated that the NSI was able to discriminate malingered responses from medical and psychiatric patient responses. However, applying a lie scale derived from previous research with the NSI did not allow discrimination between the malingered group and the psychiatric patients. Use of a factor solution derived from earlier research may offer not only greater prediction in detection of malingerers, but also evaluation of symptom profiles of medical and psychiatric patients. The NSI may provide an efficient screen for exaggerated symptoms as well as an indication of the level of general neuropsychological functioning of the patient when included in a neuropsychological evaluation.<br>Department of Educational Psychology
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Falkeborn, Rikard. "Evaluation of Differential Algebraic Elimination Methods for Deriving Consistency Relations from an Engine Model." Thesis, Linköping University, Department of Electrical Engineering, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-7973.
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<p>New emission legislations introduced in the European Union and the U.S. have made truck manufacturers face stricter requirements for low emissions and on-board diagnostic systems. The on-board diagnostic system typically consists of several tests that are run when the truck is driving. One way to construct such tests is to use so called consistency relations. A consistency relation is a relation with known variables that in the fault free case always holds. Calculation of a consistency relation typically involves eliminating unknown variables from a set of equations.</p><p>To eliminate variables from a differential polynomial system, methods from differential algebra can be used. In this thesis, the purely algebraic Gröbner basis algorithm and the differential Rosenfeld-Gröbner algorithm implemented in the Maple package Diffalg have been compared and evaluated. The conclusion drawn is that there are no significant differences between the methods. However, since using Gröbner basis requires differentiations to be made in advance, the recommendation is to use the Rosenfeld-Gröbner algorithm.</p><p>Further, attempts to calculate consistency relations using the Rosenfeld-Gröbner algorithm have been made to a real application, a model of a Scania diesel engine. These attempts did not yield any successful results. It was only possible to calculate one consistency relation. This can be explained by the high complexity of the model.</p>
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Diaz, Jesse P. "Profile analysis of measure of vigilance and observed behavior in the differential diagnosis of attention-deficit hyperactivity disorder." Virtual Press, 1997. http://liblink.bsu.edu/uhtbin/catkey/1063207.
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Ward's method of cluster analysis was utilized to partition the clinical profiles of 74 students completed at a midwestern university's school psychology training clinic. The Conners' Continuous Performance Test and the Parent Rating Scale of the Behavioral Assessment System for Children provided the clustering variables. The neuropsychological literature predicted three groups; ADHD - Primarily Inattentive Type, ADHD - Primarily Hyperactive-Impulsive Type, and ADHD - Mixed Type based on errors of omission and commission on measures of vigilance, along with parental rankings on internalized and externalized behavior.Cluster Analysis 1 (N = 74) identified three clusters but failed to support the initial hypothesis. Clusters differentiated between clinical, at risk, and average range behavioral rankings, especially on those behaviors that are immediately noticeable and conflict with structured situations.Cluster Analysis 2 (n = 26) was limited to those with initial referral questions of an attentional disorder. All procedures of analysis 1 were repeated with this subset. Three clusters supported the inattentive and hyperactive profiles predicted.<br>Department of Educational Psychology