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Journal articles on the topic 'Differential WBC'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

BORTON, DOROTHY. "WBC Count and Differential." Nursing 26, no. 9 (1996): 26–32. http://dx.doi.org/10.1097/00152193-199609000-00011.

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Ahn, Soon-Hyun. "WBC Differential Count for Diagnosis of Lymphadenopathy." Otolaryngology–Head and Neck Surgery 143, no. 2_suppl (2010): P212—P213. http://dx.doi.org/10.1016/j.otohns.2010.06.880.

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Magierowicz, Marion, Nicolas Lechevalier, Nicolas Freynet, et al. "Reference Values for WBC Differential by Hematoflow Analysis." American Journal of Clinical Pathology 151, no. 3 (2018): 324–27. http://dx.doi.org/10.1093/ajcp/aqy147.

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Habasha, F. G., and M. H. Hussain. "Cytological analysis of transtracheal washes from healthy camels in Al-Diwaniya province." Al-Qadisiyah Journal of Veterinary Medicine Sciences 13, no. 1 (2014): 124. http://dx.doi.org/10.29079/vol13iss1art292.

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This study was conducted to quantify the cytological parameters; total protein TP, white blood cells count WBC and differential WBC; from transtracheal washes TTW (sometimes called transtracheal aspirate)from thirty healthy camels in Al-diwaniya province. Both sexes were included and the animals ranged in 5-10 years old. The total protein measured by the spectrophotometer ranked in 6.2-7.9 mg/dl, WBC was 595-643/μl while the differential WBC record 60% lymphocytes, 28% macrophages, 10% neutrophils, 1% eosinophils, and 1% basophils. There was no obvious regard to gender or age on these paramete

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Golding, Christian N., Frederik Schaltz-Buchholzer, Lilica Sanca, et al. "Feasibility of manual white blood cell counts as a predictor of neonatal sepsis in a low-resource setting." Transactions of The Royal Society of Tropical Medicine and Hygiene 114, no. 8 (2020): 566–74. http://dx.doi.org/10.1093/trstmh/traa023.

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Abstract Background Manual white blood cell (WBC) differential counts as a predictor for neonatal sepsis development in a low-resource setting have not been thoroughly evaluated. We hypothesized that manual differentiation (specifically immature:total [I:T] neutrophil ratios) would be feasible and useful as an adjunct to predict early-onset neonatal sepsis (EONS). Secondarily, we hypothesized that vaccination with bacillus Calmette-Guérin (BCG) and oral polio vaccine (OPV) could alter WBC differential counts and thus might reduce its predictive performance. Methods We performed a prospective c

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Ouijdane KAJJOUNE, Hajiba AZZA, Salma ROUHI, Wafae QUIDDI, and Sanae SAYAGH. "Performance evaluation of digital morphology analyzer CellaVision DM1200." GSC Advanced Research and Reviews 23, no. 1 (2025): 048–61. https://doi.org/10.30574/gscarr.2025.23.1.0108.

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Introduction: For white blood cell (WBC) differentials, manual counting is the standard method, but blood smears can now be automatically analyzed thanks to advancements in digital imaging technologies. In this study, we aimed to evaluate the performance of CellaVision DM1200 on white blood cell differentials and erythrocyte abnormalities, using blood smears from normal and abnormal samples. The pre-classification and reclassification of WBCs by CellaVision were compared to the reference manual count. Methods: Our evaluation for CELLAVISION DM1200 took several steps initiating by precision whi

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Gac, F., J. B. Thibert, C. Le Berre, et al. "Evaluation of CytoDiff™on cord blood WBC differential." International Journal of Laboratory Hematology 35, no. 1 (2012): 46–54. http://dx.doi.org/10.1111/j.1751-553x.2012.01460.x.

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Haun, Daniel E., Argie P. Leach, Deborah F. Fink, and Gary Lipscomb. "A Better Way To Assess WBC Differential Counting Skills." Laboratory Medicine 31, no. 6 (2000): 329–33. http://dx.doi.org/10.1309/5lh9-vfqg-6a8n-2wvu.

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Kim, Kyoung-Sun, Jae-Hwan Kim, Hye-Mee Kwon, et al. "Neutrophilia is more predictive than increased white blood cell counts for short-term mortality after liver transplantation in patients with acute-on-chronic liver failure." Anesthesia and Pain Medicine 18, no. 4 (2023): 389–96. http://dx.doi.org/10.17085/apm.23048.

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Background: Acute-on-chronic liver failure (ACLF) is a life-threatening disease that requires urgent liver transplantation (LT). Accurate identification of high-risk patients is essential for predicting post-LT survival. The chronic liver failure consortium ACLF score is a widely accepted risk-stratification score that includes total white blood cell (WBC) counts as a component. This study aimed to evaluate the predictive value of total and differential WBC counts for short-term mortality following LT in patients with ACLF.Methods: A total of 685 patients with ACLF who underwent LT between Jan

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Nimisha, Gajera, Gohel Vishaldeep, Kansagra Bhavin, Vala NIleshwari, and V.S.Joshi. "STUDY OF RELATIONSHIP BETWEEN BLOOD PARAMETERS WITH MYOCARDIAL INFRACTIONS." International Journal of Basic & Applied Physiology 3, no. 1 (2014): 80–84. https://doi.org/10.5281/zenodo.4476129.

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Background: The aim of this study was to find out the changes in blood parameters in a group of myocardial infarction patients in Jamnagar, Gujarat. Method: In this cross sectional study conducted at the medicine clinic in GGH General Hospital, Jamnagar between May 2012 and April 2013, a total of 100 subjects were included. Parameters like Hemoglobin, RBC count, WBC count, Platelet count, Haematocrit, ESR, Mean corpuscular volume, mean corpuscular hemoglobin, Mean corpuscular hemoglobin concentration, packed cell volume, Differential WBC count used. Result: The results of present study reveale

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Sooriyaarachchi, Piumika, Ranil Jayawardena, Toby Pavey, and Neil A. King. "Shift Work is Associated with an Elevated White Blood Cell Count: A Systematic Review and Meta-Analysis." Indian Journal of Occupational and Environmental Medicine 27, no. 4 (2023): 278–85. http://dx.doi.org/10.4103/ijoem.ijoem_326_22.

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The white blood cell (WBC) count increases significantly in reaction to infections and certain chronic diseases. Shift employment increases the risk for chronic low-grade inflammation and the progression of several chronic diseases. The objective of this study was to systematically evaluate the evidence from studies on total and differential WBC counts in shift employees. A literature search was performed in PubMed®, Web of Science, and Scopus databases using keywords for research published before March 1, 2022. A meta-analysis was conducted for total and differential WBC counts using a random

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Jelek, Jolica, Jole Stark, Marija Nemec, et al. "The influence of age, farm, and physiological status on pig hematological profiles." Journal of Swine Health and Production 26, no. 2 (2018): 72–78. http://dx.doi.org/10.54846/jshap/1049.

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Objectives: To evaluate influence of age, farm, and physiological status on pig hematological profiles. Materials and methods: This study was carried out on five 1-site, farrow-to-finish pig farms in Slovenia, where a total of 382 clinically normal pigs were sampled. All farms were free of Aujeszky’s disease (pseudorabies), classical swine fever, and porcine reproductive and respiratory syndrome. Blood samples were taken from the anterior vena cava. Hematological analyses were performed with an automated hematological analyser. The following hematological variables were measured: red blood cel

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Brown, Gregory P., and Richard Shine. "Maternal body size influences offspring immune configuration in an oviparous snake." Royal Society Open Science 3, no. 3 (2016): 160041. http://dx.doi.org/10.1098/rsos.160041.

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Like most ectothermic vertebrates, keelback snakes ( Tropidonophis mairii ) do not exhibit parental care. Thus, offspring must possess an immune system capable of dealing with challenges such as pathogens, without assistance from an attendant parent. We know very little about immune system characteristics of neonatal reptiles, including the magnitude of heritability and other maternal influences. To identify sources of variation in circulating white blood cell (WBC) concentrations and differentials, we examined blood smears from 246 hatchling snakes and their field-caught mothers. WBC concentr

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CHANDRAMAOULY, BELUR S., ROBIN P. CUNNINGHAM, and FRANK J. SCHIANO. "Skeletal Photopenic Lesions on lndium-111 WBC Imaging; Differential Diagnosis." Clinical Nuclear Medicine 18, no. 5 (1993): 439–40. http://dx.doi.org/10.1097/00003072-199305000-00016.

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Kizhina, Aleksandra, Lyudmila Uzenbaeva, Ekaterina Antonova, Vladimir Belkin, Viktor Ilyukha, and Evgeniy Khizhkin. "Hematological parameters in hibernating Eptesicus nilssonii (Mammalia: Chiroptera) collected in Northern European Russia." Acta Chiropterologica 20, no. 1 (2018): 273–83. https://doi.org/10.5281/zenodo.13454662.

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(Uploaded by Plazi for the Bat Literature Project) The Northern bat, Eptesicus nilssonii, is the most common species among northern chiropteran populations. The species is noted for its long hibernation period with low mortality rate. We investigated the morphology of E. nilssonii blood cells during hibernation, hematological parameters including hemoglobin level, red blood cell (RBC) count, total white blood cell (WBC) count, and differential WBC count. The study revealed changes of several hematological parameters in hibernating bats, with some variation during the hibernation season. Hibern

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Kizhina, Aleksandra, Lyudmila Uzenbaeva, Ekaterina Antonova, Vladimir Belkin, Viktor Ilyukha, and Evgeniy Khizhkin. "Hematological parameters in hibernating Eptesicus nilssonii (Mammalia: Chiroptera) collected in Northern European Russia." Acta Chiropterologica 20, no. 1 (2018): 273–83. https://doi.org/10.5281/zenodo.13454662.

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(Uploaded by Plazi for the Bat Literature Project) The Northern bat, Eptesicus nilssonii, is the most common species among northern chiropteran populations. The species is noted for its long hibernation period with low mortality rate. We investigated the morphology of E. nilssonii blood cells during hibernation, hematological parameters including hemoglobin level, red blood cell (RBC) count, total white blood cell (WBC) count, and differential WBC count. The study revealed changes of several hematological parameters in hibernating bats, with some variation during the hibernation season. Hibern

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Kizhina, Aleksandra, Lyudmila Uzenbaeva, Ekaterina Antonova, Vladimir Belkin, Viktor Ilyukha, and Evgeniy Khizhkin. "Hematological parameters in hibernating Eptesicus nilssonii (Mammalia: Chiroptera) collected in Northern European Russia." Acta Chiropterologica 20, no. 1 (2018): 273–83. https://doi.org/10.5281/zenodo.13454662.

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(Uploaded by Plazi for the Bat Literature Project) The Northern bat, Eptesicus nilssonii, is the most common species among northern chiropteran populations. The species is noted for its long hibernation period with low mortality rate. We investigated the morphology of E. nilssonii blood cells during hibernation, hematological parameters including hemoglobin level, red blood cell (RBC) count, total white blood cell (WBC) count, and differential WBC count. The study revealed changes of several hematological parameters in hibernating bats, with some variation during the hibernation season. Hibern

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18

Kizhina, Aleksandra, Lyudmila Uzenbaeva, Ekaterina Antonova, Vladimir Belkin, Viktor Ilyukha, and Evgeniy Khizhkin. "Hematological parameters in hibernating Eptesicus nilssonii (Mammalia: Chiroptera) collected in Northern European Russia." Acta Chiropterologica 20, no. 1 (2018): 273–83. https://doi.org/10.5281/zenodo.13454662.

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(Uploaded by Plazi for the Bat Literature Project) The Northern bat, Eptesicus nilssonii, is the most common species among northern chiropteran populations. The species is noted for its long hibernation period with low mortality rate. We investigated the morphology of E. nilssonii blood cells during hibernation, hematological parameters including hemoglobin level, red blood cell (RBC) count, total white blood cell (WBC) count, and differential WBC count. The study revealed changes of several hematological parameters in hibernating bats, with some variation during the hibernation season. Hibern

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19

Kizhina, Aleksandra, Lyudmila Uzenbaeva, Ekaterina Antonova, Vladimir Belkin, Viktor Ilyukha, and Evgeniy Khizhkin. "Hematological parameters in hibernating Eptesicus nilssonii (Mammalia: Chiroptera) collected in Northern European Russia." Acta Chiropterologica 20, no. 1 (2018): 273–83. https://doi.org/10.5281/zenodo.13454662.

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(Uploaded by Plazi for the Bat Literature Project) The Northern bat, Eptesicus nilssonii, is the most common species among northern chiropteran populations. The species is noted for its long hibernation period with low mortality rate. We investigated the morphology of E. nilssonii blood cells during hibernation, hematological parameters including hemoglobin level, red blood cell (RBC) count, total white blood cell (WBC) count, and differential WBC count. The study revealed changes of several hematological parameters in hibernating bats, with some variation during the hibernation season. Hibern

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20

Hansen, Seth, Jessie Edwards, Stephanie Lau, et al. "225 In vitro digestion and conventional hydration assays reveal differential physicochemical properties in soybean meal and hulls." Journal of Animal Science 103, Supplement_1 (2025): 264. https://doi.org/10.1093/jas/skaf102.293.

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Abstract Soybean meal (SBM) fiber composition is primarily galactooligosaccharides, galactomannans, and arabinogalactans, while soybean hulls (SH) contain more pectins, cellulose, and hemicellulose. These carbohydrates affect the physicochemical properties of SBM and SH in swine gastrointestinal tract. Implementing in vitro foregut digestion (IVD) hydration assays may yield a more realistic expression of dietary fiber’s physicochemical properties. This study aimed to compare conventional hydration assays with IVD methodology to enhance understanding of SBM and SH physicochemical behavior. A to

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21

Jorczyk, Maximilian. "Akute respiratorische Infektionen im Kindesalter: Nutzenbewertung von Leukozytenzahl, CRP und PCT." Kompass Pneumologie 10, no. 2 (2022): 72–73. http://dx.doi.org/10.1159/000522594.

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<b>Background:</b> There is a lack of studies comparing PCT, CRP and WBC levels in the differential diagnosis of acute bacterial, viral, and mycoplasmal respiratory tract infections. It is necessary to explore the correlation between above markers and different types of ARTI. <b>Methods:</b> 108 children with confirmed bacterial infection were regarded as group A, 116 children with virus infection were regarded as group B, and 122 children with mycoplasmal infection were regarded as group C. The levels of PCT, CRP and WBC of the three groups were detected and compared.

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Fenelus, Maly, Ryan M. Golden, Tamiqua Graham, Rachel J. So, Jessica Lynn Bautista, and Ellinor I. B. Peerschke. "Choosing Wisely: Optimizing Outpatient Cancer Care and Conserving Resources with a New Algorithm to Report Automated ANC Results in the Presence of Analyzer Flags." Blood 134, Supplement_1 (2019): 4683. http://dx.doi.org/10.1182/blood-2019-128963.

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Background: The complete blood cell count (CBC) with white blood cell (WBC) differential is an essential laboratory test used to screen cancer patients prior to chemotherapy. WBC differential analysis is performed by automated hematology platforms in the clinical laboratory. However, automated results often require manual review if the analysis is associated with instrument flags that indicate the potential for inaccurate results. Review and confirmation of flagged results by laboratory technologists is time consuming and increases test result turnaround time (TAT), thereby prolonging patient

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Velizarova, Milena, Teodora Yacheva, Mariana Genova, and Dobrin Svinarov. "Evaluation of automated hematology analyzer DYMIND DH76 compared to SYSMEX XN 1000 system." Journal of Medical Biochemistry 40, no. 4 (2021): 367–77. http://dx.doi.org/10.5937/jomb0-28836.

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Background: DYMIND DH76 (DYMIND BIOTECH, China) is a new automated hematology system designed to provide CBC count, including a 5-part WBC differential count, and its analytical performance should be assessed before adoption for clinical use. Methods: The analyzer was evaluated according to the International Council for Standardization in Haematology guideline. The purposes of this study were to assess its analytical performance in comparison to SYSMEX XN 1000 hematology analyzer currently used in our laboratory, as well as to compare the automated and manual WBC differential. Results: Within-

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Fulkerson, Daniel H., Ahilan Sivaganesan, Jason D. Hill, et al. "Progression of cerebrospinal fluid cell count and differential over a treatment course of shunt infection." Journal of Neurosurgery: Pediatrics 8, no. 6 (2011): 613–19. http://dx.doi.org/10.3171/2011.8.peds11236.

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Object The physiological reaction of CSF white blood cells (WBCs) over the course of treating a shunt infection is undefined. The authors speculated that the CSF WBC count varies with different infecting organisms in peak level and differential percentage of polymorphonuclear (PMN) leukocytes, lymphocytes, monocytes, and eosinophils. The authors hope to identify clinically useful trends in the progression of CSF WBCs by analyzing a large group of patients with successfully treated shunt infections. Methods The authors reviewed 105 successfully treated cases of shunt infections at Riley Hospita

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Bailey, Cleta Sue, and Robert J. Higgins. "Characteristics of cerebrospinal fluid associated with canine granulomatous meningoencephalomyelitis: A retrospective study." Journal of the American Veterinary Medical Association 188, no. 4 (1986): 418–21. https://doi.org/10.2460/javma.1986.188.04.418.

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SUMMARY Cerebrospinal fluid of 22 dogs with histologically confirmed granulomatous meningoencephalomyelitis was analyzed, retrospectively. Seventeen dogs had cisternal csf analysis, 4 dogs had lumbar csf analysis, and 1 dog had both. For cisternal csf, the mean ± sem total wbc count was 800.8 ±300.9 cells/μl. The wbc differential count was predominantly lymphoplasmacytic cells, but 13 of the 18 cisternal csf had polymorphonuclear (pmn) cells, and the mean ± sem pmn cell percentage was 18.6 ± 5.3%. The mean ± sem total protein content of cisternal csf was 255.8 ± 98 mg/dl. Of 5 cisternal csf pr

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Nava, María Paz, José Pablo Veiga, and Marisa Puerta. "White blood cell counts in house sparrows (Passer domesticus) before and after moult and after testosterone treatment." Canadian Journal of Zoology 79, no. 1 (2001): 145–48. http://dx.doi.org/10.1139/z00-191.

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In this study two experiments were run in parallel. To evaluate the possible influence of moult and age on differential white blood cell (WBC) counts, we captured juvenile and adult house sparrows (Passer domesticus) and housed them in outdoor aviaries. Blood was collected twice, before and after moult. Numbers of basophils, lymphocytes, and monocytes were higher in juveniles than in adults, whereas numbers of eosinophilic cells were similar in the two age groups. Moult induced an increase in basophils and monocytes in both juveniles and adults. This indicates that moult and age impose differe

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Hu, Yazhen, Xiaolei Wei, Zhiwei Liao, et al. "Transcriptome Analysis Provides Insights into the Markers of Resting and LPS-Activated Macrophages in Grass Carp (Ctenopharyngodon idella)." International Journal of Molecular Sciences 19, no. 11 (2018): 3562. http://dx.doi.org/10.3390/ijms19113562.

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Macrophages are very versatile immune cells, with the characteristics of a proinflammatory phenotype in response to pathogen-associated molecular patterns. However, the specific activation marker genes of macrophages have not been systematically investigated in teleosts. In this work, leukocytes (WBC) were isolated using the Percoll gradient method. Macrophages were enriched by the adherent culture of WBC, then stimulated with lipopolysaccharide (LPS). Macrophages were identified by morphological features, functional activity and authorized cytokine expression. Subsequently, we collected sampl

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Gupta, Tavish, and Debdatta Basu. "Utility of scatterplot patterns of automated hematology analysers in white blood cell disorders – A comparative study with peripheral blood smears." Asian Journal of Medical Sciences 11, no. 5 (2020): 29–34. http://dx.doi.org/10.3126/ajms.v11i5.29049.

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Background: Advances in automated blood cell counting offer new possibilities to analyse leukocyte differentials by fluorescence RNA/DNA staining combined with scattered light intensity technologies. Aims and Objectives: The purpose of this study is to identify the scatterplot patterns in normal cell counts and various White Blood Cell (WBC) disorders and to assess their efficacy compared to a peripheral blood smear (PBS) in the diagnosis of WBC disorders. Materials and Methods: A three-phased descriptive study analysing a total of 933 EDTA blood samples. The total leucocyte count,

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Perné, Andrea, Johannes A. Hainfellner, Irene Womastek, Alexander Haushofer, Thomas Szekeres, and Ilse Schwarzinger. "Performance Evaluation of the Sysmex XE-5000 Hematology Analyzer for White Blood Cell Analysis in Cerebrospinal Fluid." Archives of Pathology & Laboratory Medicine 136, no. 2 (2012): 194–98. http://dx.doi.org/10.5858/arpa.2011-0030-oa.

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Context.—The newest generation hematology analyzer, Sysmex XE-5000 (Sysmex Corporation, Kobe, Japan) is equipped with an improved body fluid analysis mode. Objective.—To evaluate the applicability of the XE-5000 analyzer to white blood cell (WBC) analysis in cerebrospinal fluid (CSF). Design.—A total of 425 routinely collected, consecutive CSF samples were included in the study. For a comparison of total WBC counts, the results of routine chamber counts were grouped into categories of 0 to 5 (n = 330), &gt;5 to 10 (n = 36), &gt;10 to 50 (n = 39), &gt;50 to 200 (n = 15), and &gt

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Piccione, G., M. Rizzo, F. Arfuso, et al. "Leukocyte modifications during the first month after foaling in mares and their newborn foals." Polish Journal of Veterinary Sciences 18, no. 3 (2015): 621–25. http://dx.doi.org/10.1515/pjvs-2015-0080.

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Abstract During early post-partum period both neonatal foals and peripartum mares are most susceptible to diseases. The aim of this study was to establish physiologic modifications of leukogram during the first month after foaling in mares and their newborn foals. To this end blood samples were collected from nine mares and nine foals (T0-T10), every three days from the 1st day until the 30th day after foaling. Samples were analysed for white blood cell (WBC) count and differential leucocyte counts. Two-way repeated measure analysis of variance (ANOVA) showed, in postpartum mares WBC showed si

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Hung, Shih-Chiang, Chen-Cheng Yang, Chu-Feng Liu, et al. "The Association Pattern between Ambient Temperature Change and Leukocyte Counts." International Journal of Environmental Research and Public Health 18, no. 13 (2021): 6971. http://dx.doi.org/10.3390/ijerph18136971.

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Ambient temperature change is one of the risk factors of human health. Moreover, links between white blood cell counts (WBC) and diseases have been revealed in the literature. Still, we do not know of any association between ambient temperature change and WBC counts. The aim of our study is to investigate the relationship between ambient temperature change and WBC counts. We conducted this two-year population-based observational study in Kaohsiung city, recruiting voluntary community participants. Total WBC and differential counts, demographic data and health hazard habits were collected and m

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Boskabady, Mohammad Hossein, Fatemeh Amin, and Farzaneh Shakeri. "The Effect of Curcuma longa on Inflammatory Mediators and Immunological, Oxidant, and Antioxidant Biomarkers in Asthmatic Rats." Evidence-Based Complementary and Alternative Medicine 2021 (November 12, 2021): 1–13. http://dx.doi.org/10.1155/2021/4234326.

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The effects of Curcuma longa (C. longa) on total and differential WBC, inflammatory and immunologic mediators, and oxidant and antioxidant biomarkers in bronchoalveolar lavage fluid (BALF) of rats model of asthma were assessed. Animals were divided to 5 groups including control (C), asthma (sensitized to ovalbumin), and asthmatic groups treated with 0.75, 1.50, and 3.00 mg/ml C. longa (CL) and 1.25 μg/ml dexamethasone (D) (8 rats in each group). Total and differential WBC count, concentrations of phospholipase A2 (PLA2), total protein (TP), interferon-gamma (IFN-γ), interleukin-4 (IL-4), immun

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Sabater-Martos, Marta, Martin Clauss, Ana Ribau, and Ricardo Sousa. "Differential synovial fluid white blood cell count for the diagnosis of chronic peri-prosthetic joint infection – a systematic review and meta-analysis." Journal of Bone and Joint Infection 10, no. 3 (2025): 165–84. https://doi.org/10.5194/jbji-10-165-2025.

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Abstract. Introduction: Peri-prosthetic joint infection (PJI) is a significant complication of arthroplasty, lacking a single gold standard diagnostic test. Synovial fluid white blood cell (WBC) count and polymorphonuclear neutrophil (PMN) proportion are widely used diagnostic tools, but their optimal cutoffs remain unclear, particularly for chronic PJI. Material and methods: This systematic review and meta-analysis included 74 studies published between 2000 and 2024. Data on diagnostic performance (sensitivity, specificity, and diagnostic odds ratios – DORs) of WBC count and PMN proportions w

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Abu Khadija, Haitham, Gera Gandelman, Omar Ayyad, et al. "Differential systemic inflammatory responses after TAVI: The role of self versus balloon expandable devices." PLOS ONE 16, no. 10 (2021): e0258963. http://dx.doi.org/10.1371/journal.pone.0258963.

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Objective Transcatheter aortic valve implantation (TAVI) provokes early injury response, represented in part by dynamic changes in the inflammatory markers. The association of self-expanding valves (SEVs) and balloon-expandable valves (BEVs) with the consequent inflammatory response remains uncertain. Materials and methods Patients with severe symptomatic aortic stenosis who underwent transfemoral TAVI: SEVs or BEVs, from January 2010 to December 2019 were enrolled. Whole white blood cells (WBC) and subpopulation dynamics as well the neutrophil to lymphocyte ratio (NLR) were evaluated. Results

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Bigorra, Laura, Iciar Larriba, and Ricardo Gutiérrez-Gallego. "Machine learning algorithms for the detection of spurious white blood cell differentials due to erythrocyte lysis resistance." Journal of Clinical Pathology 72, no. 6 (2019): 431–37. http://dx.doi.org/10.1136/jclinpath-2019-205820.

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AimsRed blood cell (RBC) lysis resistance interferes with white blood cell (WBC) count and differential; still, its detection relies on the identification of an abnormal scattergram, and this is not clearly adverted by specific flags in the Beckman-Coulter DXH-800. The aims were to analyse precisely the effect of RBC lysis resistance interference in WBC counts, differentials and cell population data (CPD) and then to design, develop and implement a novel diagnostic machine learning (ML) model to optimise the detection of samples presenting this phenomenon.MethodsWBC counts, differentials and C

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Higgins, Renee, Michael Adams, Nick Haase, et al. "Advancing Hematological Point-of-Care Diagnostics: Development and Multi-Site Evaluation of a Novel AI-Enabled Diagnostic Device for CBC Analysis with Differential." Blood 142, Supplement 1 (2023): 2285. http://dx.doi.org/10.1182/blood-2023-190949.

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Introduction: A complete blood count (CBC) with differential is a routine blood test that provides essential health information that is fundamental for maintaining wellness. While many other routine tests can be run in Point of Care (POC) settings, a CBC with differential is largely confined to central laboratory testing environments. Truvian is in late-stage development of a fully automated device that runs a TruWellness Panel (TM) incorporating all routine tests - a CBC with 3-part differential, comprehensive metabolic panel (CMP), lipid panel, HbA1c and TSH in a single run with 300uL of who

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Herman, Nicolas, Catherine Trumel, Anne Geffré, et al. "Hematology reference intervals for adult cows in France using the Sysmex XT-2000iV analyzer." Journal of Veterinary Diagnostic Investigation 30, no. 5 (2018): 678–87. http://dx.doi.org/10.1177/1040638718790310.

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In order to develop bovine hematology reference intervals (RIs) in accordance with new international recommendations, we analyzed 156 blood specimens of healthy adult dairy and beef cows from 32 farms with a Sysmex XT-2000iV analyzer, and by manual scoring of platelet clumps and white blood cell (WBC) differential. We established RIs by the nonparametric method, and examined effects of age, production type (beef vs. dairy), and stage of lactation. RIs could not be determined for platelet count and indices because clumps were observed in 80% of specimens. Optical and impedance red blood cell (R

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Mihalič, René, Jurij Zdovc, Peter Brumat, and Rihard Trebše. "Synovial fluid interleukin-6 is not superior to cell count and differential in the detection of periprosthetic joint infection." Bone & Joint Open 1, no. 12 (2020): 737–42. http://dx.doi.org/10.1302/2633-1462.112.bjo-2020-0166.r1.

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Aims Synovial fluid white blood cell (WBC) count and percentage of polymorphonuclear cells (%PMN) are elevated at periprosthetic joint infection (PJI). Leucocytes produce different interleukins (IL), including IL-6, so we hypothesized that synovial fluid IL-6 could be a more accurate predictor of PJI than synovial fluid WBC count and %PMN. The main aim of our study was to compare the predictive performance of all three diagnostic tests in the detection of PJI. Methods Patients undergoing total hip or knee revision surgery were included. In the perioperative assessment phase, synovial fluid WBC

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Lismayanti, Leni, and Mansyur Arif. "White Blood Cell and Peripheral Blast Counts in Leukemia Patients with Non-Graying WBC-Diff Scattergram." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 31, no. 1 (2024): 61–65. http://dx.doi.org/10.24293/ijcpml.v31i1.2222.

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Graying scattergram of White Blood Cell differential (WBC-diff) is often accompanied by blasts in the blood and/or leukocytosis in leukemia patients. Therefore, monitoring White Blood Cell (WBC) and peripheral blast count is crucial for patient management. In contrast, patients with non-graying WBC-diff scattergrams may have varying WBC counts and peripheral blasts. This study aimed to establish the cut-off values of WBC and peripheral blast counts that could predict a non-graying scattergram in leukemia patients. A retrospective descriptive study with a cross-sectional design analyzed seconda

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Slim, Christiaan L., Brigitte A. Wevers, Martijn W. H. J. Demmers, et al. "Multicenter performance evaluation of the Abbott Alinity hq hematology analyzer." Clinical Chemistry and Laboratory Medicine (CCLM) 57, no. 12 (2019): 1988–98. http://dx.doi.org/10.1515/cclm-2019-0155.

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Abstract Background Alinity hq (Abbott) is a new high-throughput hematology analyzer that exclusively employs optical principles for detecting and enumerating blood cells. It reports 29 parameters, including a six-part white blood cell (WBC) differential. The aim of this multicenter study was to evaluate the analytical and clinical performance of the Alinity hq. Methods Complete blood count (CBC) results and morphological flagging were compared to that of CELL-DYN Sapphire (Abbott) and 2 × 200-cell manual differential results, on 1473 whole-blood samples from a well-defined patient population

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Costa, Céline, Ana Patrícia Sousa, Grasiene Silva, et al. "Analytical Validation of Two Point-of-Care Assays for Hematological Analysis in the Miranda Donkey." Veterinary Sciences 11, no. 9 (2024): 450. http://dx.doi.org/10.3390/vetsci11090450.

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Miranda donkeys are an endangered autochthonous breed of Portugal. The HemoCue WBC DIFF and HemoCue Hb 201 portable analyzers, developed as a simplified alternative method for total and differential WBC count and hemoglobin measurement, respectively, may be relevant tools in veterinary practice. This study aimed to validate these instruments using Miranda donkey blood samples. For the HemoCue WBC DIFF, most parameters showed acceptable intra- and inter-assay precision with coefficients of variation (CV) below 5%, except for monocytes and eosinophils with higher CVs. The HemoCue Hb 201 showed C

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Velidedeoglu, Mehmet, Berrin Papila Kundaktepe, Hulya Aksan, and Hafize Uzun. "Preoperative Fibrinogen and Hematological Indexes in the Differential Diagnosis of Idiopathic Granulomatous Mastitis and Breast Cancer." Medicina 57, no. 7 (2021): 698. http://dx.doi.org/10.3390/medicina57070698.

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Background and Aim: Studies on hematological parameters in the differential diagnosis of idiopathic granulomatous mastitis (IGM) and breast cancer (BC) are limited. This study investigated whether preoperative fibrinogen and hematological indexes can be used in the differential diagnosis of patients with IGM and early-onset BC. Methods: Fifty patients with BC, 55 patients with IGM, and 50 healthy volunteer women were included in the study. Results: There was a statistically significant difference between the IGM and the BC with respect to fibrinogen, fibrinogen/albumin (Fib/Alb) ratio, C-react

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Toth, Linda A., and James M. Krueger. "Hematologic effects of exposure to three infective agents in rabbits." Journal of the American Veterinary Medical Association 195, no. 7 (1989): 981–86. https://doi.org/10.2460/javma.1989.195.07.981.

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Summary Infectious disease is typically accompanied by changes in the number and types of circulating leukocytes. To examine the effects of infectious challenge on the distribution of rabbit wbc, rabbits were inoculated iv with Streptococcus pyogenes, Escherichia coli, or Candida albicans. Blood was collected prior to and every 6 to 12 hours ajter inoculation for 48 hours. Infectious challenge did not substantially alter total wbc counts, but did cause neutrophilia and lymphopenia for 6 to 48 hours after inoculation. Similar patterns of leukocyte distribution were observed in rabbits with natu

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Koppar, Anant R., and Venugopalachar Sridhar. "An Automated Method for Differential Blood Counting Using Microscope Color Image of Isolated WBC." International Journal of E-Health and Medical Communications 1, no. 4 (2010): 35–48. http://dx.doi.org/10.4018/jehmc.2010100103.

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Healthcare Delivery Systems are becoming overloaded in developed and developing countries. It is imperative that more efficient and cost effective processes be employed by innovative applications of technology in the delivery system. One such process in Haematology that needs attention is “Generation of report on the Differential Count of Blood”. Most rural centers in India still employ traditional, manual processes to identify and count White Blood Cells under a microscope. This traditional method of manually counting the white blood cells is prone to human error and time consuming. Medical I

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Mukhtar, Isyaku Gwarzo, and Precious Ishaya Salama. "Cognition and its relationship with differential white cell count among obese undergraduates in Nigeria." Amrita Journal of Medicine 20, no. 1 (2024): 13–19. http://dx.doi.org/10.4103/amjm.amjm_65_23.

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Abstract Introduction: Studies have linked obesity with cognitive impairment and low-grade inflammation; however, results have been inconsistent. The aim of this study was to compare global cognitive function and its relationship with indices of obesity and total and differential white blood cell (WBC) counts in obese and normal-weight undergraduates in Kano, Nigeria. Materials and Methods: Eighty participants (40 obese and 40 normal weights) were randomly recruited for this case–control descriptive study. Anthropometric indices were measured according to the World Health Organization’s Stepwi

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Köhler-Forsberg, Ole, Louisa G. Sylvia, Charles L. Bowden, et al. "Correlation between white blood cell count and mood-stabilising treatment response in two bipolar disorder trials." Acta Neuropsychiatrica 31, no. 04 (2019): 230–34. http://dx.doi.org/10.1017/neu.2019.19.

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AbstractBackground:Immune system markers may predict affective disorder treatment response, but whether an overall immune system marker predicts bipolar disorder treatment effect is unclear.Methods:Bipolar CHOICE (N = 482) and LiTMUS (N = 283) were similar comparative effectiveness trials treating patients with bipolar disorder for 24 weeks with four different treatment arms (standard-dose lithium, quetiapine, moderate-dose lithium plus optimised personalised treatment (OPT) and OPT without lithium). We performed secondary mixed effects linear regression analyses adjusted for age, gender, smok

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Brigden, Malcolm L., and Martin G. Horak. "Incidence and Clinical Significance of Unsuspected Eosinophilia Discovered by Automated WBC Differential Counting." Laboratory Medicine 24, no. 3 (1993): 173–76. http://dx.doi.org/10.1093/labmed/24.3.173.

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Korelitz, BI, J. Zlatanic, MJ Smith, RJ Lipe, PJ Baiocco, and GW Gleim. "Significance of WBC differential when leukopenia is induced by 6-MP for IBD." Gastroenterology 113, no. 5 (1997): 1810–11. http://dx.doi.org/10.1053/gast.1997.v113.agast971131810b.

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Vélez, M. d. S. López, T. González Cejudo, M. d. M. Maldonado Montoro, and T. De Haro Munoz. "Evaluation of CBC and CRP with two automated hematology analyzer microsemi CRP for 3-part WBC differential and CRP and Pentra MS CRP for 5-part WBC differential and CRP." Clinica Chimica Acta 493 (June 2019): S662. http://dx.doi.org/10.1016/j.cca.2019.03.1395.

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Huang, Xiwei, Jixuan Liu, Jiangfan Yao, et al. "Deep-Learning Based Label-Free Classification of Activated and Inactivated Neutrophils for Rapid Immune State Monitoring." Sensors 21, no. 2 (2021): 512. http://dx.doi.org/10.3390/s21020512.

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The differential count of white blood cells (WBCs) is one widely used approach to assess the status of a patient’s immune system. Currently, the main methods of differential WBC counting are manual counting and automatic instrument analysis with labeling preprocessing. But these two methods are complicated to operate and may interfere with the physiological states of cells. Therefore, we propose a deep learning-based method to perform label-free classification of three types of WBCs based on their morphologies to judge the activated or inactivated neutrophils. Over 90% accuracy was finally ach

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