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Journal articles on the topic 'Differentiated function'

Author: Grafiati

Published: 28 May 2022

Last updated: 31 July 2025

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1

MacDonald, Caroline, Maureen Vass, Brian Willett, Alexander Scott, and Helen Grant. "Expression of Liver Functions in Imrnortalised Rot Hepotocyte Cell Lines." Human & Experimental Toxicology 13, no. 6 (1994): 439–44. http://dx.doi.org/10.1177/096032719401300613.

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The differentiated hepatic function of two rat liver cell lines, P9 and SV40RH1, immortalised by transfection with SV40 DNA has been investigated in terms of the glutathione synthesis, and the activities of γ-glutamyltransferase, glutathione-S-transferase and UDP-glucuronosyltransferase. SV40RH1 is a highly differentiated cell line at early passage, but the expression of some aspects of its differentiated phenotype is unstable and some functions are lost by passage 12-13. P9 is a less-well differentiated cell line, with relatively stable expression of functions between passages 4 and 13. In te

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Zhunussova, B. A., Zh M. Baimurynov та L. M. Kuleimenova. "Бірлән шылауының қазіргі сипаты мен қызметі". Bulletin of the L.N. Gumilyov Eurasian National University. Philology series 151, № 2 (2025): 62–77. https://doi.org/10.32523/2616-678x-2025-151-2-62-77.

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It is known that the functional word “and” is formed from the ancient Turkic particle “birlan” and is differentiated by grammatical function and meaning as a conjunction and ending. However, it is known that modern variants of the particle “birlan”, common to the Turkic peoples, have not received unambiguous recognition in the grammar of the Turkic languages. There are specific reasons for this. The article attempts to compile a systematic description of the functional words that arose from the particle “birlan”. For this purpose, the etymological works of domestic and Soviet Turkologists and

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Pettit, A. R., C. Quinn, K. P. MacDonald, et al. "Nuclear localization of RelB is associated with effective antigen-presenting cell function." Journal of Immunology 159, no. 8 (1997): 3681–91. http://dx.doi.org/10.4049/jimmunol.159.8.3681.

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Abstract Dendritic cells (DC) are potent APCs that enter resting tissues as precursors and, after Ag exposure, differentiate and migrate to draining lymph nodes. The phenotype of RelB knockout mice implicates this member of the NF kappa B/Rel family in DC differentiation. To further elucidate the role of RelB in DC differentiation, mRNA, intracellular protein expression, and DNA binding activity of RelB were examined in immature and differentiated human DC, as well as other PB mononuclear cell populations. RelB protein and mRNA were detected constitutively in lymphocytes and in activated monoc

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Thomas, Hugh. "Differentiated pluripotent stem cells restore thyroid function." Nature Reviews Endocrinology 12, no. 1 (2015): 5. http://dx.doi.org/10.1038/nrendo.2015.193.

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Tang, M. J., and R. L. Tannen. "Metabolic substrates alter attachment and differentiated functions of proximal tubule cell culture." Journal of the American Society of Nephrology 4, no. 11 (1994): 1908–11. http://dx.doi.org/10.1681/asn.v4111908.

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Proximal tubules cultured in vitro gradually lose their differentiated functions. Because standard culture media lacks several substrates important for renal proximal tubule oxidative metabolism, whether a mixture of substrates including butyrate, alanine, and lactate (BAL) would modify growth and/or differentiated function of proximal tubular cells in culture was examined. Tubules cultured in media supplemented with 2 mM butyrate, alanine, and lactate exhibited enhanced attachment but did not exhibit an altered growth rate. Higher levels of phosphoenolpyruvate carboxykinase and leucine-amino

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Yamamoto, Naoki, Noriko Hiramatsu, Mahito Ohkuma, et al. "Novel Technique for Retinal Nerve Cell Regeneration with Electrophysiological Functions Using Human Iris-Derived iPS Cells." Cells 10, no. 4 (2021): 743. http://dx.doi.org/10.3390/cells10040743.

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Regenerative medicine in ophthalmology that uses induced pluripotent stem cells (iPS) cells has been described, but those studies used iPS cells derived from fibroblasts. Here, we generated iPS cells derived from iris cells that develop from the same inner layer of the optic cup as the retina, to regenerate retinal nerves. We first identified cells positive for p75NTR, a marker of retinal tissue stem and progenitor cells, in human iris tissue. We then reprogrammed the cultured p75NTR-positive iris tissue stem/progenitor (H-iris stem/progenitor) cells to create iris-derived iPS (H-iris iPS) cel

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Bouzioukh, Farima, Gaël Daoudal, Julien Falk, Dominique Debanne, Geneviève Rougon, and Valérie Castellani. "Semaphorin3A regulates synaptic function of differentiated hippocampal neurons." European Journal of Neuroscience 23, no. 9 (2006): 2247–54. http://dx.doi.org/10.1111/j.1460-9568.2006.04783.x.

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Shashikanth, Nitesh, Sunil Yeruva, Ma Lora Drizella M. Ong, Matthew A. Odenwald, Roman Pavlyuk, and Jerrold R. Turner. "Epithelial Organization: The Gut and Beyond." Comprehensive Physiology 7, no. 4 (2017): 1497–518. https://doi.org/10.1002/j.2040-4603.2017.tb00785.x.

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ABSTRACTEpithelial cells are essential to the survival and homeostasis of complex organisms. These cells cover the surfaces of all mucosae, the skin, and other compartmentalized structures essential to physiological function. In addition to maintenance of barriers that separate internal and external compartments, epithelia display a variety of organ‐specific differentiated functions. Function is reflected in overall epithelial structure and organization, shape of individual cells, and proteins expressed by these cells. More than one epithelial cell type is often present within a single organ a

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Urbin, M. A., David Stodden, and Glenn Fleisig. "Overarm Throwing Variability as a Function of Trunk Action." Journal of Motor Learning and Development 1, no. 4 (2013): 89–95. http://dx.doi.org/10.1123/jmld.1.4.89.

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Individual body segment actions evolve during throwing skill development. Maximal trunk involvement is typically the last feature of the movement pattern to fully develop. The current study examined developmental levels of trunk action and the associated variability in the throwing motion. The throwing motions of children and adolescents were analyzed via motion capture and trunk actions were classified as exhibiting no rotation (n = 7), blocked rotation (n = 6), or differentiated rotation (n = 11). Results indicated nonrotators exhibited greater variability than blocked-rotators in maximum hu

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Peng, Guangyong, Jian Ye, Xinming Su, et al. "Human tumor-infiltrating Th17 cells have the capacity to differentiate into IFN-gamma+ and FOXP3+ T cells with potent suppressive function (66.27)." Journal of Immunology 186, no. 1_Supplement (2011): 66.27. http://dx.doi.org/10.4049/jimmunol.186.supp.66.27.

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Abstract Accumulating evidence suggests that T-helper 17 (Th17) cells and regulatory T (Treg) cells may exhibit development plasticity, and that CD4+ Tregs can differentiate into IL-17-producing T cells; however, whether Th17 cells can reciprocally convert into Tregs has not been described. In this study, we generated Th17 clones from tumor-infiltrating T lymphocytes (TILs). We showed that Th17 clones generated from TILs can differentiate into IFN-gamma-producing and FOXP3+ cells after in vitro stimulation with OKT3 and allogeneic peripheral blood mononuclear cells (PBMCs). We further demonstr

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Ribeiro, Tatiana, Aurelie Picard, Elfi Ducrocq, et al. "The Hematopoietic Supportive Function of Adult Bone Marrow Mesenchymal Stem Cells Is Lost after Differentiation Induction towards Adipocytic, Osteoblastic and Vascular Smooth Muscle Lineages." Blood 112, no. 11 (2008): 4742. http://dx.doi.org/10.1182/blood.v112.11.4742.4742.

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Abstract The bone marrow (BM) hematopoietic stem cell (HSC) niche is a specialized structure of the microenvironment, which supports survival and regulates HSC function (i.e. the HSC control of the self-renewal/differentiation balance and migration). The supportive cells involved in the HSC niche are usually named as “stromal cells” but their precise nature remains a matter of debate (in particular, to know whether these cells belong to osteoblastic or to vascular smooth muscle lineage). Mesenchymal stem cells (MSCs) that are present into the BM are characterized by a broad differentiation pot

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Piotrovskaya, Larisa A. "DIFFERENTIATED APPROACH TO STUDYING *THE EMOTIVE FUNCTION OF INTONATION." Theoretical and Applied Linguistics, no. 3 (2019): 143–63. http://dx.doi.org/10.22250/2410-7190_2019_5_3_143_163.

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The current paper has several aims: on the one hand, it is meant to determine the principles for selecting language material for experimental phonetic research of prosodic means to express emotions, on the other hand it applies the results of this study (i) to determine the place of emotive intonation patterns in the Russian intonation system, (ii) to provide enough ground for identifying 3 aspects of emotive function of intonation: communicative-emotive, emotive-differentiating and form-building. I argue that, first, the focus of the corresponding phonetic studies should be emotive utterances

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Shannon, J. M., S. D. Jennings, and L. D. Nielsen. "Modulation of alveolar type II cell differentiated function in vitro." American Journal of Physiology-Lung Cellular and Molecular Physiology 262, no. 4 (1992): L427—L436. http://dx.doi.org/10.1152/ajplung.1992.262.4.l427.

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We have investigated whether the loss of differentiated function observed in adult rat alveolar type II cells cultured on a substratum that promotes cell spreading and flattening represents a reversible phenotypic change. Cells were cultured for 4 and 8 days in association with fetal rat lung fibroblast feeder layers on either attached collagen gels, which promote the loss of differentiated function, or on floating collagen gels, which support differentiation. A fifth group of cultures were maintained as attached gels for 4 days, then detached and cultured as floating gels for the remaining 4

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Kwon, Chae-Ri, and Hoo-Jo Hong. "A Study on English Subjects Differentiation Method according to Career in Academic High School." Korean Association For Learner-Centered Curriculum And Instruction 24, no. 9 (2024): 689–708. http://dx.doi.org/10.22251/jlcci.2024.24.9.689.

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Objectives The purposes of this study is to develop career-differentiated English subject syllabus necessary to implement a career-differentiated curriculum in academic high school. Methods To achieve this, the researcher presented a career-differentiated design proposal for English subjects to 130 teachers who specialized in English or educational curriculum. The approach involved obtaining feedback from them and tentatively finalizing the design proposal based on their opinions. Results This study drew the following conclusions. Firstly, it is necessary to differentiate English subject accor

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Foulks, Jason M., Gopal K. Marathe, Noemi Michetti, et al. "PAF-acetylhydrolase expressed during megakaryocyte differentiation inactivates PAF-like lipids." Blood 113, no. 26 (2009): 6699–706. http://dx.doi.org/10.1182/blood-2008-11-186312.

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Abstract Platelet activating factor (PAF) and PAF-like lipids induce inflammatory responses in target cells. These lipid mediators are inactivated by PAF-acetylhydrolase (PAF-AH). The PAF signaling system affects the growth of hematopoietic CD34+ cells, but roles for PAF-AH in this process are unknown. Here, we investigated PAF-AH function during megakaryopoiesis and found that human CD34+ cells accumulate this enzymatic activity as they differentiate toward megakaryocytes, consistent with the expression of mRNA and protein for the plasma PAF-AH isoform. Inhibition of endogenous PAF-AH activit

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Harimoto, Kozo, Yoshiaki Nishio, Hideaki Someya, Tomohito Sato, Masataka Ito, and Masaru Takeuchi. "Anti-inflammatory actions of ripasudil ameliorate experimental autoimmune uveoretinitis in the acute phase." BMJ Open Ophthalmology 10, no. 1 (2025): e001981. https://doi.org/10.1136/bmjophth-2024-001981.

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IntroductionRho-associated protein kinases (ROCKs) are a key regulator of T cell function, influencing a wide range of processes from activation to differentiation. Experimental autoimmune uveoretinitis (EAU) is an animal model of human non-infectious uveitis. This study aimed to evaluate the suppressive effects of ripasudil, a ROCK inhibitor, on ocular inflammation when administered from the onset of EAU and to elucidate the underlying mechanisms of its inhibitory effects.MethodsEAU was induced in wild-type C57BL/6 mice by immunisation with IRBP peptide. Ripasudil or its vehicle, PBS, was int

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Liu, Chunmei, Qun Wang, Fengming Liu, and Lining Zhang. "Rapid change of PO2 promoted dendritic cells to induce a strong Th1 cell immune response with decreased Foxp3+Tregs (89.11)." Journal of Immunology 182, no. 1_Supplement (2009): 89.11. http://dx.doi.org/10.4049/jimmunol.182.supp.89.11.

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Abstract Ischemia-reperfusion injury (IRI) can be found in transplantation and other ischemic syndromes in multiple organ systems including kindey, brain, heart and liver, this pathogenesis of IRI is complex and incompletely understood. It has been suggested that reoxygenation after hypoxia is a crucial mechanism mediating organ injury in IRI. Well, dendritic cells (DCs), the critical immune cells linking innate and adaptive immunity, are often exposed to various oxygen tensions under physiological and pathological conditions, such as ischemia-reperfusion. However, the effects of various oxyge

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Wittig, Ilka, Juliana Heidler, Heiko Giese, and Ralf P. Brandes. "Maintenance on mitochondrial complexes ensures bioenergetic function in differentiated cells." Biochimica et Biophysica Acta (BBA) - Bioenergetics 1863 (September 2022): 148702. http://dx.doi.org/10.1016/j.bbabio.2022.148702.

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Yamaya, M., W. E. Finkbeiner, S. Y. Chun, and J. H. Widdicombe. "Differentiated structure and function of cultures from human tracheal epithelium." American Journal of Physiology-Lung Cellular and Molecular Physiology 262, no. 6 (1992): L713—L724. http://dx.doi.org/10.1152/ajplung.1992.262.6.l713.

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Here we describe the conditions which allow cultured human tracheal epithelial cells to retain the ion transport properties and ultrastructure of the original tissue. The order of potency of growth supports and media additives in elevating baseline short-circuit current (Isc) and responses to mediators were vitrogen gel (VIT) greater than extracellular matrix from bovine corneal endothelial cells (ECM) greater than human placental collagen (HPC), and 2% Ultroser G serum substitute (USG) greater than 5% fetal calf serum (FCS) greater than defined growth factors (GF). For all combinations of med

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Bhadriraju, Kiran, and Linda K. Hansen. "Hepatocyte adhesion, growth and differentiated function on RGD-containing proteins." Biomaterials 21, no. 3 (2000): 267–72. http://dx.doi.org/10.1016/s0142-9612(99)00175-1.

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21

Ginsberg, Jody, and Patricia G. Murray. "Protein kinase C activators modulate differentiated thyroid function in vitro." FEBS Letters 206, no. 2 (1986): 309–12. http://dx.doi.org/10.1016/0014-5793(86)81002-x.

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22

Gerstenfeld, Louis C., Stewart D. Chipman, Julie Glowacki, and Jane B. Lian. "Expression of differentiated function by mineralizing cultures of chicken osteoblasts." Developmental Biology 122, no. 1 (1987): 49–60. http://dx.doi.org/10.1016/0012-1606(87)90331-9.

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23

Xu, Kaipeng, Jinnan Wang, Jingjing Wang, Xiahui Wang, Yanyan Chi, and Xiao Zhang. "Environmental function zoning for spatially differentiated environmental policies in China." Journal of Environmental Management 255 (February 2020): 109485. http://dx.doi.org/10.1016/j.jenvman.2019.109485.

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Hadley, Mark A., Stephen W. Byers, Carlos A. Suárez-Quian, daniel Djakiew, and Martin Dym. "In vitro models of differentiated sertoli cell structure and function." In Vitro Cellular & Developmental Biology 24, no. 6 (1988): 550–57. http://dx.doi.org/10.1007/bf02629090.

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Rowse, Linda M., M. Desiree Watson, Glenn K. Walker, Mark R. Emmerling, Harry X. LeVine та Roy D. Schwarz. "Oligomeric Aβ affects cell function in NGF-differentiated PC12 cells". Neurobiology of Aging 21 (травень 2000): 13. http://dx.doi.org/10.1016/s0197-4580(00)82734-7.

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Korchagina, M. O., E. N. Andreeva, M. S. Sheremeta, and G. A. Melnichenko. "Female reproductive function after radioiodine therapy for differentiated thyroid carcinoma." Problems of Endocrinology 71, no. 1 (2024): 72–82. https://doi.org/10.14341/probl13407.

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Differentiated thyroid carcinoma (DTC) is the most common endocrine cancer, accounting for 90–95% of thyroid malignancy and predominant in the female population of all age groups. Surgery is the standard primary treatment for patients with DTC, followed by radioactive iodine therapy (RAIT) when indicated. After the main treatment, patients receive thyroid hormone therapy in a variety of regimens, either as a replacement therapy or as a therapy intended to suppress secretion of thyroid-stimulating hormone (TSH).The impact of RAIT on the health of individuals with DTC has been studied for years.

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Schwager, Joseph, Albine Bompard, Daniel Raederstorff, Hubert Hug та Igor Bendik. "Resveratrol and ω-3 PUFAs Promote Human Macrophage Differentiation and Function". Biomedicines 10, № 7 (2022): 1524. http://dx.doi.org/10.3390/biomedicines10071524.

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Monocytes differentiate into M1 and M2 macrophages, which are classically activated by microbial products such as LPS or IFN-γ and interleukins (e.g., the anti-inflammatory and Th2 promoting IL-4), respectively. The contribution of nutrients or nutrient-based substances such as ω-3 polyunsaturated fatty acids (ω-3 PUFAs) and resveratrol (Res) on the differentiation and function of M1 and M2 macrophages was evaluated. THP-1 cells and peripheral blood mononuclear cells (PBMCs) were differentiated into M1 and M2 cells and activated with LPS/IFN-γ or IL-4/IL-13. Macrophage lineage specific surface

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Gurtner, Aymone, Isabella Manni, Paola Fuschi, et al. "Requirement for Down-Regulation of the CCAAT-binding Activity of the NF-Y Transcription Factor during Skeletal Muscle Differentiation." Molecular Biology of the Cell 14, no. 7 (2003): 2706–15. http://dx.doi.org/10.1091/mbc.e02-09-0600.

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NF-Y is composed of three subunits, NF-YA, NF-YB, and NF-YC, all required for DNA binding. All subunits are expressed in proliferating skeletal muscle cells, whereas NF-YA alone is undetectable in terminally differentiated cells in vitro. By immunohistochemistry, we show that the NF-YA protein is not expressed in the nuclei of skeletal and cardiac muscle cells in vivo. By chromatin immunoprecipitation experiments, we demonstrate herein that NF-Y does not bind to the CCAAT boxes of target promoters in differentiated muscle cells. Consistent with this, the activity of these promoters is down-reg

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Konrády, András. "Differentiated thyroid cancer – 2009." Orvosi Hetilap 152, no. 5 (2011): 163–70. http://dx.doi.org/10.1556/oh.2011.29028.

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Three years ago continental guidelines were published referring management and follow-up of low risk thyroid cancer patients. The aim of this paper is to summarize the changes and new directions in this field. High risk patients require another protocol. Neck ultrasound plays important role in differential diagnosis and in detecting recurrences. Some new ultrasound techniques are discussed, too. FDG-PET can help to solve the problem of patients having negative scan and increased thyroglobulin level. In recent years there was an expansion of our knowledge about the pathomechanism of thyroid can

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Sadikovic, Samra. "Determination of a jump by conjugate Fourier-Jacobi series." Filomat 32, no. 8 (2018): 2745–54. http://dx.doi.org/10.2298/fil1808745s.

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We prove the equiconvergence related to conjugate Fourier-Jacobi series and differentiated Fourier-Jacobi series for functions of harmonic bounded variation. A jump of a such function is determined by the partial sums of its conjugate Fourier-Jacobi series.

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Chaudhary, Jaideep, Andrea S. Cupp, and Michael K. Skinner. "Role of Basic-Helix-Loop-Helix Transcription Factors in Sertoli Cell Differentiation: Identification of an E-Box Response Element in the Transferrin Promoter*." Endocrinology 138, no. 2 (1997): 667–75. http://dx.doi.org/10.1210/endo.138.2.4942.

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Abstract Sertoli cells are critical for testicular function and maintenance of the spermatogenic process. The induction of Sertoli cell differentiation in the embryo promotes testicular development and male sex determination. The progression of Sertoli cell differentiation during puberty promotes the onset of spermatogenesis. The maintenance of optimal Sertoli cell differentiation in the adult is required for spermatogenesis to proceed. The current study was designed to investigate the transcriptional regulation of Sertoli cell differentiation through the analysis of a previously identified ma

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Khairunnisa, Muna, Cita Dwi Rosita, Setiyani Setiyani, and Mohd Hasril Amiruddin. "Development of Differentiated Learning Module with Undo Procedure to Improve Learning Outcomes Students on Function Inversion Material." IJORER : International Journal of Recent Educational Research 6, no. 1 (2025): 19–32. https://doi.org/10.46245/ijorer.v6i1.729.

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Objective: This study aims to develop a teaching module focusing on differentiated learning by applying the undo procedure to improve student learning outcomes and understanding of inverse functions. Method: This study is the development of a differentiated learning teaching module on the inverse function material using the four-D (4-D) model from Thiagarajan (Define, Design, Develop, and Disseminate). Meanwhile, to determine the effectiveness of the teaching module, the research subjects were students of class XI SMAIQu (Qurani Islamic High School) Al Bahjah Cirebon. Results: The teaching mod

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Inoue, Tomoaki, Norihiko Iwazaki, Tetsuro Araki, and Hiroko Hitotsumachi. "Human-Induced Pluripotent Stem Cell-Derived Hepatocytes and their Culturing Methods to Maintain Liver Functions for Pharmacokinetics and Safety Evaluation of Pharmaceuticals." Current Pharmaceutical Biotechnology 21, no. 9 (2020): 773–79. http://dx.doi.org/10.2174/1389201021666200131123524.

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Human hepatocytes are essential cell types for pharmacokinetics and the safety evaluation of pharmaceuticals. However, widely used primary hepatocytes with individual variations in liver function lose those functions rapidly in culture. Hepatic cell lines are convenient to use but have low liver functions. Human-Induced Pluripotent Stem (hiPS) cells can be expanded and potentially differentiated into any cell or tissue, including the liver. HiPS cell-derived Hepatocyte-Like Cells (hiPSHeps) are expected to be extensively used as consistent functional human hepatocytes. Many laboratories are in

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Harris, Paul, and Rebekah Richert. "The Ghost in My Body: Children's Developing Concept of the Soul." Journal of Cognition and Culture 6, no. 3-4 (2006): 409–27. http://dx.doi.org/10.1163/156853706778554913.

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AbstractTwo experiments were conducted to explore whether children, who have been exposed to the concept of the soul, differentiate the soul from the mind. In the first experiment, 4- to 12-year-old children were asked about whether a religious ritual affects the mind, the brain, or the soul. The majority of the children claimed that only the soul was different after baptism. In a follow-up study, 6- to 12-year-old children were tested more explicitly on what factors differentiate the soul from the mind and the brain. Children differentiated the soul from the mind and the brain along two dimen

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Hendel, Russell Jay. "A Transdisciplinary Approach to Differentiated Instruction." Journal of Systemics, Cybernetics and Informatics 20, no. 1 (2022): 65–85. http://dx.doi.org/10.54808/jsci.20.01.65.

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Differentiated instruction (DI) improves student performance and student satisfaction especially when preliminary instructor training is provided. However, the DI literature is overwhelming, excessively challenging many instructors to create a DI for multiple learning styles. This paper employs a transdisciplinary approach to address this gap between theory and challenging operational implementation. #1) The discipline of architecture introduced the approach of universal design, advocating that new buildings be initially built to allow universal access; this contrasts with the prior method of

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Dreyer, Henriette H. M., Eleonora Sofie van Tuyll van Serooskerken, Lisa W. Rodenburg, et al. "Airway Epithelial Cultures of Children with Esophageal Atresia as a Model to Study Respiratory Tract Disorders." Children 10, no. 6 (2023): 1020. http://dx.doi.org/10.3390/children10061020.

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Esophageal atresia (EA) is a rare birth defect in which respiratory tract disorders are a major cause of morbidity. It remains unclear whether respiratory tract disorders are in part caused by alterations in airway epithelial cell functions such as the activity of motile cilia. This can be studied using airway epithelial cell culture models of patients with EA. Therefore, the aim of this study was to evaluate the feasibility to culture and functionally characterize motile cilia function in the differentiated air–liquid interface cultured airway epithelial cells and 3D organoids derived from na

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Deutinger, Maria, Werner Girsch, Georg Burggasser, Alfred Windisch, Norbert Mayr, and Gerhard Freilinger. "Clinical and electroneurographic evaluation of sensory/motor-differentiated nerve repair in the hand." Journal of Neurosurgery 78, no. 5 (1993): 709–13. http://dx.doi.org/10.3171/jns.1993.78.5.0709.

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✓ In 17 patients acetylcholinesterase activity was used to differentiate between sensory and motor fascicles in median and ulnar nerve repair of the hand. Eleven patients received follow-up evaluation 1 to 11 years after surgery, and at that time clinical and electroneurographic examinations were performed to evaluate the techniques. Clinical examination showed that four patients had regained on average 71.9% of hand function after median nerve repair, one patient had regained 83.6% of hand function after ulnar nerve repair, four patients had regained on average 53.3% of hand function after me

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Canale, Domenico, Claudia Ceccarelli, Carolina Caglieresi, et al. "Effects of radioiodine treatment for differentiated thyroid cancer on testis function." Clinical Endocrinology 82, no. 2 (2014): 295–99. http://dx.doi.org/10.1111/cen.12514.

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ZAKARIJA, M., and J. M. McKENZIE. "Influence of Cytokines on Growth and Differentiated Function of FRTL5 Cells*." Endocrinology 125, no. 3 (1989): 1260–65. http://dx.doi.org/10.1210/endo-125-3-1260.

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Kurmann, Anita A., Maria Serra, Finn Hawkins, et al. "Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells." Cell Stem Cell 17, no. 5 (2015): 527–42. http://dx.doi.org/10.1016/j.stem.2015.09.004.

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Prinsen, Hester T., Esther N. Klein Hesselink, Adrienne H. Brouwers, et al. "Bone Marrow Function After131I Therapy in Patients With Differentiated Thyroid Carcinoma." Journal of Clinical Endocrinology & Metabolism 100, no. 10 (2015): 3911–17. http://dx.doi.org/10.1210/jc.2015-2124.

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RAJAGOPAL, M., T. L. TOLLNER, W. E. FINKBEINER, G. N. CHERR, and J. H. WIDDICOMBE. "DIFFERENTIATED STRUCTURE AND FUNCTION OF PRIMARY CULTURES OF MONKEY OVIDUCTAL EPITHELIUM." In Vitro Cellular & Developmental Biology - Animal 42, no. 8 (2006): 248. http://dx.doi.org/10.1290/0602015.1.

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Boorstein, R. J., D. D. Levy, and G. W. Teebor. "5-Hydroxymethyluracil-DNA glycosylase activity may be a differentiated mammalian function." Mutation Research/DNA Repair Reports 183, no. 3 (1987): 257–63. http://dx.doi.org/10.1016/0167-8817(87)90008-3.

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Liu, Liping, Jing Tan, Baoyuan Li, et al. "Construction of functional pancreatic artificial islet tissue composed of fibroblast-modified polylactic-co-glycolic acid membrane and pancreatic stem cells." Journal of Biomaterials Applications 32, no. 3 (2017): 362–72. http://dx.doi.org/10.1177/0885328217722041.

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Objective To improve the biocompatibility between polylactic- co-glycolic acid membrane and pancreatic stem cells, rat fibroblasts were used to modify the polylactic- co-glycolic acid membrane. Meanwhile, we constructed artificial islet tissue by compound culturing the pancreatic stem cells and the fibroblast-modified polylactic- co-glycolic acid membrane and explored the function of artificial islets in diabetic nude mice. Methods Pancreatic stem cells were cultured on the fibroblast-modified polylactic- co-glycolic acid membrane in dulbecco's modified eagle medium containing activin-A, β-cat

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Romanowska, Małgorzata. "Urban soundscape preferences in relation to the function of a place: Case studies in Warsaw." Miscellanea Geographica 22, no. 4 (2018): 237–42. http://dx.doi.org/10.2478/mgrsd-2018-0027.

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Abstract The survey interviewed three hundred and nine people in five public places within Warsaw. The aim of the survey was to examine if people’s sound preferences are related to a place’s function and how these preferences differentiate. A further aim of this research was to gather users’ ideas for making city soundscapes more pleasant. The results showed that people generally prefer natural and human sounds, but do not like mechanical sounds; the importance of specific sounds are differentiated in relation to the function and history of a place. The main way to make urban places sound bett

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Майданюк, В., С. Бондаренко та В. Грабчак. "АНАЛІТИЧНІ ФУНКЦІЇ НЕЛІНІЙНИХ ПАРАМЕТРІВ ПОЛЬОТУ СНАРЯДА". Collection of scientific works of Odesa Military Academy, № 19 (30 червня 2023): 5–16. http://dx.doi.org/10.37129/2313-7509.2023.19.5-16.

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When calculating projectile flight trajectories, an urgent issue is the definition and representation of aerodynamic forces (moments) and parameters of the atmosphere, which are significantly non-linear in nature, in the system of mathematical models - differential equations of spatial motion of projectiles. A significant component of the error in determining the aerodynamic force is introduced by the operation of numerical differentiation of tabular values of aerodynamic coefficients, which are included as components in systems of differential equations. In this direction, a scientific approa

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Qiu, Shimeng, Yaling Li, Yuki Imakura, et al. "An Efficient Method for the Differentiation of Human iPSC-Derived Endoderm toward Enterocytes and Hepatocytes." Cells 10, no. 4 (2021): 812. http://dx.doi.org/10.3390/cells10040812.

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The endoderm, differentiated from human induced pluripotent stem cells (iPSCs), can differentiate into the small intestine and liver, which are vital for drug absorption and metabolism. The development of human iPSC-derived enterocytes (HiEnts) and hepatocytes (HiHeps) has been reported. However, pharmacokinetic function-deficiency of these cells remains to be elucidated. Here, we aimed to develop an efficient differentiation method to induce endoderm formation from human iPSCs. Cells treated with activin A for 168 h expressed higher levels of endodermal genes than those treated for 72 h. Usin

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Chen, Tung-Ti, and Jean Y. J. Wang. "Establishment of Irreversible Growth Arrest in Myogenic Differentiation Requires the RB LXCXE-Binding Function." Molecular and Cellular Biology 20, no. 15 (2000): 5571–80. http://dx.doi.org/10.1128/mcb.20.15.5571-5580.2000.

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ABSTRACT The crystal structure of the A-B domain of RB has defined the binding pocket for the LXCXE peptide motif. Using the crystal structure as a guide, we have inactivated the LXCXE-binding pocket by replacing N757 with Phe [to obtain RB(N757F)]. RB(N757F) does not bind to viral oncoproteins but retains the ability to bind and inhibit E2F. RB(N757F) is less effective than the wild-type RB [RB(WT)] in repressing E2F-regulated transcription, and its repression activity is not affected by trichostatin A, an inhibitor of histone deacetylases. However, RB(N757F) is as effective as RB(WT) in supp

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Becker, Robert, Marina Leone, and Felix Engel. "Microtubule Organization in Striated Muscle Cells." Cells 9, no. 6 (2020): 1395. http://dx.doi.org/10.3390/cells9061395.

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Distinctly organized microtubule networks contribute to the function of differentiated cell types such as neurons, epithelial cells, skeletal myotubes, and cardiomyocytes. In striated (i.e., skeletal and cardiac) muscle cells, the nuclear envelope acts as the dominant microtubule-organizing center (MTOC) and the function of the centrosome—the canonical MTOC of mammalian cells—is attenuated, a common feature of differentiated cell types. We summarize the mechanisms known to underlie MTOC formation at the nuclear envelope, discuss the significance of the nuclear envelope MTOC for muscle function

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K. Vijaya. "The Markovian Batch Arrival Queue with Differentiated Vacation." Communications on Applied Nonlinear Analysis 31, no. 3s (2024): 197–211. http://dx.doi.org/10.52783/cana.v31.759.

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A Poisson Batch Arrival Queueing Model with a single server taking two different vacations at various rates is being considered for the study. The probability generating function method of the different states is considered for deriving the various performance measures of the states; numerical cases and cost studies are also extended.

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