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1

S., Altman. "Difficullt problems, difficult thoughts." Biochimie 84, no. 8 (2002): 691–92. http://dx.doi.org/10.1016/s0300-9084(02)01437-2.

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2

Harris, Verne, and Sello Hatang. "The difficulty of calling Derrida ‘difficult’." Scrutiny2 5, no. 1 (2000): 78–79. http://dx.doi.org/10.1080/18125440008565957.

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3

Taylor, Maggie. "Difficult, Difficult, Lemon, Difficult." Narrative Inquiry in Bioethics 14, no. 1 (2024): 28–30. http://dx.doi.org/10.1353/nib.2024.a934186.

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4

Kelly, Ciarán P., and J. Thomas LaMont. "Clostridium difficile— More Difficult Than Ever." New England Journal of Medicine 359, no. 18 (2008): 1932–40. http://dx.doi.org/10.1056/nejmra0707500.

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5

Pop-Vicas, Aurora, and Marguerite A. Neill. "Clostridium difficile: the increasingly difficult pathogen." Critical Care 12, no. 1 (2008): 114. http://dx.doi.org/10.1186/cc6773.

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6

Nagella, Naresh, Khenj-Jim Lim, and Amay Parikh. "Clostridium difficile outcomes difficult to generalize." Critical Care 17, no. 1 (2013): 415. http://dx.doi.org/10.1186/cc11935.

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7

Rupnik, Maja, and Sandra Janezic. "Clostridioides (Clostridium) difficile – Interesting and difficult." Anaerobe 60 (December 2019): 102124. http://dx.doi.org/10.1016/j.anaerobe.2019.102124.

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8

&NA;. "Predicting Difficult Airways Using the Intubation Difficulty Scale." Survey of Anesthesiology 54, no. 5 (2010): 221. http://dx.doi.org/10.1097/sa.0b013e3181f21ff2.

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9

Nagella, Naresh, Kheng-Jim Lim, and Amay Parikh. "Correction: Clostridium difficile outcomes difficult to generalize." Critical Care 18, no. 1 (2014): 402. http://dx.doi.org/10.1186/cc13698.

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10

YAMANE, Yasuo, and Katsuhiko SEKIYA. "An Evaluation of Difficulty in Machining Difficult-to-Cut Materials by using Difficult-to-Cut Rating." Journal of the Japan Society for Precision Engineering, Contributed Papers 70, no. 3 (2004): 407–11. http://dx.doi.org/10.2493/jspe.70.407.

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11

Dr., Maira Mansoor Dr. Rija Khalid Dr. Muhammad Usman Khalid. "POSITIVE PREDICTIVE VALUE OF RESTRICTED NECK MOVEMENT IN ASSESSING DIFFICULT INTUBATION TAKING INTUBATION DIFFICULTY SCALE AS GOLD STANDARD." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 05 (2018): 4483–92. https://doi.org/10.5281/zenodo.1256353.

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<strong><em>Introduction: </em></strong><em>Airway maintenance during anesthesia is crucial for adequate oxygenation and ventilation and failure to secure airway can lead to tissue hypoxia and ultimately death. The three main causes of respiratory related injuries of anesthesia are inadequate ventilation, esophageal intubation and difficult tracheal intubation. 17% of all respiratory related injuries are due to difficult intubation and it accounts for 28% of anesthesia related deaths&#39;.</em> <strong><em>Subjects and Methods:</em></strong><em> This study involved 126 patients of both genders, aged between I8-70 years undergoing general anesthesia with endotracheal intubation on elective lists Difficult intubation was predicted on restricted neck movement (&lt;80&deg;) and was confirmed on IDS. IDS diagnosis was taken as gold standard and results of restricted neck movement were evaluated accordingly. Written informed consent was taken from every patient.</em> <strong><em>Results:</em></strong><em> The age of the patients ranged from 18 years to 70 years with a mean of 42.49 + 14.56 years. There were 64 (50.8%) male and 62 (49.2%) female patients in the study group. There were 52 (41.3%) obese patients. Difficult intubation was confirmed in 90 (71.4%) patients on intubation difficulty scale (as per operational definition). 1&#39;he frequency of difficult intubation was higher among obese patients (80.8% vs. 64.9%; p 0.052) however the difference was insignificant. There were 90 (71.4%) true positive patients with 36 false positive patients. It yielded a positive predictive value of 71.4% for restricted neck movement in the prediction of difficult intubation taking IDS as gold standard. Similar positive predictive value was observed across age, gender and obesity groups.</em> <strong><em>Conclusion:</em></strong><em> The positive predictive value of restricted neck movement (&lt;80&deg;) was found to be 71.4% in predicting difficult intubation among patients undergoing general anesthesia with endotracheal intubation on elective list while taking intubation difficulty scale as the gold standard.</em> <strong>Keywords:</strong><em> Difficult Intubation. Intubation Difficulty Scale. Restricted Neck Movement</em>.
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12

Dr., Salman Hameed Dr. Jumana Fatima Dr. Abdul Sami. "BY TAKING INTUBATION DIFFICULTY SCALE AS GOLD STANDARD IN ASSESSING DIFFICULT INTUBATION AND PREDICTIVE VALUE OF RESTRICTED NECK MOVEMENT." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 05 (2018): 4493–98. https://doi.org/10.5281/zenodo.1256355.

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<strong><em>Introduction: </em></strong><em>The three main causes of respiratory related injuries of anesthesia are inadequate ventilation, esophageal intubation and difficult tracheal intubation. 17% of all respiratory related injuries are due to difficult intubation and it accounts for 28% of anesthesia related deaths&rsquo;. Airway maintenance during anesthesia is crucial for adequate oxygenation and ventilation and failure to secure airway can lead to tissue hypoxia and ultimately death. </em> <strong><em>Subjects and Methods:</em></strong><em> This study involved 126 patients of both genders, aged between I8-70 years undergoing general anesthesia with endotracheal intubation on elective lists Difficult intubation was predicted on restricted neck movement (&lt;80&deg;) and was confirmed on IDS. IDS diagnosis was taken as gold standard and results of restricted neck movement were evaluated accordingly. Written informed consent was taken from every patient.</em> <strong><em>Results:</em></strong><em> The age of the patients ranged from 18 years to 70 years with a mean of 42.49 + 14.56 years. There were 64 (50.8%) male and 62 (49.2%) female patients in the study group. There were 52 (41.3%) obese patients. Difficult intubation was confirmed in 90 (71.4%) patients on intubation difficulty scale (as per operational definition). 1&#39;he frequency of difficult intubation was higher among obese patients (80.8% vs. 64.9%; p 0.052) however the difference was insignificant. There were 90 (71.4%) true positive patients with 36 false positive patients. It yielded a positive predictive value of 71.4% for restricted neck movement in the prediction of difficult intubation taking IDS as gold standard. Similar positive predictive value was observed across age, gender and obesity groups.</em> <strong><em>Conclusion:</em></strong><em> The positive predictive value of restricted neck movement (&lt;80&deg;) was found to be 71.4% in predicting difficult intubation among patients undergoing general anesthesia with endotracheal intubation on elective list while taking intubation difficulty scale as the gold standard.</em> <strong>Keywords:</strong> <em>Difficult Intubation. Intubation Difficulty Scale. Restricted Neck Movement.</em>
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13

Dr., Salman Hameed Dr. Jumana Fatima Dr. Abdul Sami. "BY TAKING INTUBATION DIFFICULTY SCALE AS GOLD STANDARD IN ASSESSING DIFFICULT INTUBATION AND PREDICTIVE VALUE OF RESTRICTED NECK MOVEMENT." Indo American Journal of Pharmaceutical Sciences 05, no. 06 (2018): 5142–47. https://doi.org/10.5281/zenodo.1301279.

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<strong><em>Introduction: </em></strong><em>The three main causes of respiratory related injuries of anesthesia are inadequate ventilation, esophageal intubation and difficult tracheal intubation. 17% of all respiratory related injuries are due to difficult intubation and it accounts for 28% of anesthesia related deaths&rsquo;. Airway maintenance during anesthesia is crucial for adequate oxygenation and ventilation and failure to secure airway can lead to tissue hypoxia and ultimately death. </em> <strong><em>Subjects and Methods:</em></strong><em> This study involved 126 patients of both genders, aged between I8-70 years undergoing general anesthesia with endotracheal intubation on elective lists Difficult intubation was predicted on restricted neck movement (&lt;80&deg;) and was confirmed on IDS. IDS diagnosis was taken as gold standard and results of restricted neck movement were evaluated accordingly. Written informed consent was taken from every patient.</em> <strong><em>Results:</em></strong><em> The age of the patients ranged from 18 years to 70 years with a mean of 42.49 + 14.56 years. There were 64 (50.8%) male and 62 (49.2%) female patients in the study group. There were 52 (41.3%) obese patients. Difficult intubation was confirmed in 90 (71.4%) patients on intubation difficulty scale (as per operational definition)1. The frequency of difficult intubation was higher among obese patients (80.8% vs. 64.9%; p 0.052) however the difference was insignificant. There were 90 (71.4%) true positive patients with 36 false positive patients. It yielded a positive predictive value of 71.4% for restricted neck movement in the prediction of difficult intubation taking IDS as gold standard. Similar positive predictive value was observed across age, gender and obesity groups.</em> <strong><em>Conclusion:</em></strong><em> The positive predictive value of restricted neck movement (&lt;80&deg;) was found to be 71.4% in predicting difficult intubation among patients undergoing general anesthesia with endotracheal intubation on elective list while taking intubation difficulty scale as the gold standard.</em> <strong>Keywords:</strong><em> Difficult Intubation. Intubation Difficulty Scale. Restricted Neck Movement.</em>
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14

McGough, Greta. "Difficult people Difficult people." Nursing Standard 17, no. 28 (2003): 29. http://dx.doi.org/10.7748/ns2003.03.17.28.29.b371.

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15

Funk, Amy, Chris Morton, and Teresa Bullock. "Difficult situation=difficult solution." Lab Animal 47, no. 3 (2018): 54. http://dx.doi.org/10.1038/s41684-018-0006-y.

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16

Baker, Kelly J. "Difficult Girls, Difficult Women." Women in Higher Education 27, no. 5 (2018): 16. http://dx.doi.org/10.1002/whe.20577.

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17

Dicks, Leon M. T., Lasse S. Mikkelsen, Erik Brandsborg, and Harold Marcotte. "Clostridium difficile, the Difficult “Kloster” Fuelled by Antibiotics." Current Microbiology 76, no. 6 (2018): 774–82. http://dx.doi.org/10.1007/s00284-018-1543-8.

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18

Jenior, Matthew L., and Jason A. Papin. "Clostridioides difficile: Sometimes It Pays To Be Difficult." Cell Host & Microbe 28, no. 3 (2020): 358–59. http://dx.doi.org/10.1016/j.chom.2020.08.010.

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19

White, D., and A. Garcia. "C. difficult? Surgical intervention for fulminant Clostridium difficile." American Journal of the Medical Sciences 367 (February 2024): S81—S82. http://dx.doi.org/10.1016/s0002-9629(24)00198-8.

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20

Domoratskyi, O. E., V. Ye Kryliuk, R. V. Ivanchenko, et al. "Difficult airway, extubation: difficult/failed?" EMERGENCY MEDICINE, no. 2.97 (March 1, 2019): 71–74. http://dx.doi.org/10.22141/2224-0586.2.97.2019.161645.

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21

De Marco, M. A., L. A. Nogueira-Martins, and L. Yazigi. "Difficult patients or difficult encounters?" QJM: An International Journal of Medicine 98, no. 7 (2005): 542–43. http://dx.doi.org/10.1093/qjmed/hci083.

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22

Gross, Magdalena H., and Luke Terra. "What makes difficult history difficult?" Phi Delta Kappan 99, no. 8 (2018): 51–56. http://dx.doi.org/10.1177/0031721718775680.

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All modern nation-states have periods of difficult history that teachers fail to address or address inadequately. The authors present a framework for defining difficult histories and understanding what makes them difficult. These events 1) are central to a nation’s history, 2) contradict accepted histories or values, 3) connect with present problems, 4) involve violence enacted by the state or large groups of citizens, and 5) create disequilibria that require changes to historical understandings that may carry a personal or social cost.
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23

Aoyama, K., and I. Takenaka. "Difficult laryngoscopy and difficult intubation." Anaesthesia 54, no. 8 (1999): 811–12. http://dx.doi.org/10.1046/j.1365-2044.1999.01042.x.

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24

Blackall, George F., and Michael J. Green. "“Difficult” Patients or Difficult Relationships?" American Journal of Bioethics 12, no. 5 (2012): 8–9. http://dx.doi.org/10.1080/15265161.2012.665137.

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25

Benumof, Jonathan L. "Difficult tubes and difficult airways." Journal of Cardiothoracic and Vascular Anesthesia 12, no. 2 (1998): 131–32. http://dx.doi.org/10.1016/s1053-0770(98)90317-2.

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26

Gibson, Bruce. "Difficult Intubation and Difficult Airway." Anesthesia & Analgesia 93, no. 6 (2001): 1624. http://dx.doi.org/10.1097/00000539-200112000-00065.

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27

Dimaculangan, Dennis P. "Difficult Intubation and Difficult Airway." Anesthesia & Analgesia 93, no. 6 (2001): 1624. http://dx.doi.org/10.1097/00000539-200112000-00066.

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28

Billings, Diane M., and Karren Kowalski. "Difficult Questions in Difficult Situations." Journal of Continuing Education in Nursing 39, no. 1 (2008): 16. http://dx.doi.org/10.3928/00220124-20080101-10.

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29

Owens, Erica, and Gail Ring. "Difficult Children and Difficult Parents." Journal of Family Issues 28, no. 6 (2007): 827–50. http://dx.doi.org/10.1177/0192513x06296673.

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30

Macdonald, Sharon. "Is ‘Difficult Heritage’ Still ‘Difficult’?" Museum International 67, no. 1-4 (2015): 6–22. http://dx.doi.org/10.1111/muse.12078.

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31

Lecic-Tosevski, Dusica, Mirjana Divac-Jovanovic, and Dragan Svrakic. "Difficult treatment of difficult patient." Personality and Mental Health 4, no. 3 (2010): 233–36. http://dx.doi.org/10.1002/pmh.134.

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32

Probst, Robert E. "Difficult Days and Difficult Texts." Voices from the Middle 9, no. 2 (2001): 50–53. http://dx.doi.org/10.58680/vm20012381.

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Suggests that all teaching in literature classes is in some ways preparation for events such as September 11th. Argues that teachers teach students to read events such as these by showing them how to move from reaction to reflection, and from image to empathy; and to write so that they capture their thinking, reexamine it, and present it to others.
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33

Stadler, Matthias, Christoph Niepel, and Samuel Greiff. "Easily too difficult: Estimating item difficulty in computer simulated microworlds." Computers in Human Behavior 65 (December 2016): 100–106. http://dx.doi.org/10.1016/j.chb.2016.08.025.

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34

Koh, Wonuk, Hajung Kim, Kyongsun Kim, Young-Jin Ro, and Hong-Seuk Yang. "Encountering unexpected difficult airway: relationship with the intubation difficulty scale." Korean Journal of Anesthesiology 69, no. 3 (2016): 244. http://dx.doi.org/10.4097/kjae.2016.69.3.244.

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35

Babiker, Amir, Bothainah Alaqeel, Mohammed Alsaeed, Ghadeer Aljahdali, Abdulrahman Almunif, and Sundeep Sandhu. "Uncontrolled diabetes: A difficult mother or a mother in difficulty?" Journal of Family Medicine and Primary Care 9, no. 3 (2020): 1772. http://dx.doi.org/10.4103/jfmpc.jfmpc_1157_19.

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36

O'Carroll, J. E., D. J. N. Wong, and I. Ahmad. "A difficulty with the DIFFMASK score is the difficult statistics." Anaesthesia 74, no. 10 (2019): 1337. http://dx.doi.org/10.1111/anae.14775.

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37

Fonseca, Diana, Maria Inês Graça, Carolina Salgueirinho, and Hélder Pereira. "Physiologically difficult airway: How to approach the difficulty beyond anatomy." Trends in Anaesthesia and Critical Care 48 (February 2023): 101212. http://dx.doi.org/10.1016/j.tacc.2023.101212.

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38

Khanna, Sahil, and Ryan Pardi. "Clostridioides difficile infection: curbing a difficult menace." Therapeutic Advances in Gastroenterology 15 (January 2022): 175628482210899. http://dx.doi.org/10.1177/17562848221089906.

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39

Khanna, Sahil, and Darrell S. Pardi. "Clostridium difficile infection: management strategies for a difficult disease." Therapeutic Advances in Gastroenterology 7, no. 2 (2013): 72–86. http://dx.doi.org/10.1177/1756283x13508519.

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40

Read, R. C. "Still difficult; clinical practice guidelines for Clostridium difficile infection." Clinical Microbiology and Infection 15, no. 12 (2009): 1051–52. http://dx.doi.org/10.1111/j.1469-0691.2009.03100.x.

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41

Mayorga, Esteban. "Difficult." Review: Literature and Arts of the Americas 46, no. 2 (2013): 249–53. http://dx.doi.org/10.1080/08905762.2013.840172.

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42

Brownlow, H., and S. Wallace. "A difficult intubation made more difficult." European Journal of Anaesthesiology 18, no. 6 (2001): 416. http://dx.doi.org/10.1097/00003643-200106000-00013.

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43

Jameson, Cathy. "Handling Difficult People and Difficult Situations." CRANIO® 19, no. 3 (2001): 214–18. http://dx.doi.org/10.1080/08869634.2001.11746171.

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44

Brownlow, H., and S. Wallace. "A difficult intubation made more difficult." European Journal of Anaesthesiology 18, no. 6 (2001): 416. http://dx.doi.org/10.1046/j.0265-0215.2001.00851.x.

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45

Rich, Ben A. "Distinguishing Difficult Patients From Difficult Maladies." American Journal of Bioethics 13, no. 4 (2013): 24–26. http://dx.doi.org/10.1080/15265161.2013.767957.

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46

Anderson, Patricia F., Elise Wescom, and Ruth C. Carlos. "Difficult Doctors, Difficult Patients: Building Empathy." Journal of the American College of Radiology 13, no. 12 (2016): 1590–98. http://dx.doi.org/10.1016/j.jacr.2016.09.015.

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47

Kannan, S. "‘Difficult airway’ or ‘airway made difficult’?" Anaesthesia 70, no. 6 (2015): 750–51. http://dx.doi.org/10.1111/anae.13092.

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48

Brown, Nina W. "Reconceptualizing difficult groups and difficult members." Journal of Contemporary Psychotherapy 36, no. 3 (2006): 145–50. http://dx.doi.org/10.1007/bf02729058.

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49

Agazarian, Yvonne. "The difficult patient, the difficult group." Group 11, no. 4 (1987): 205–16. http://dx.doi.org/10.1007/bf01459385.

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50

Kholova, Mohigul Shavkatovna, and Gulira Tohirova. ""DIFFICULT CHILDREN" WHOSE EDUCATION IS DIFFICULT." Multidisciplinary Journal of Science and Technology 5, no. 4 (2025): 1187–90. https://doi.org/10.5281/zenodo.15328015.

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This article broadly explains and explains the concepts that for "difficult to raise" children, the conditions in which they live, the community, class, and family they study in are of great importance; that a child grows up depending on family members, and that his or her behavior, character, and temperament are shaped like those of his or her parents and loved ones; that each parent's sweet words, kindness, and actions that show that they care and love him or her are of great importance; that ignoring a child and not pampering him or her leads to negative consequences; and that the behavior of "difficult to raise" children is directly related to the educational process.
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