Log in

Relevant bibliographies by topics / (+)-Digitoxigenin / Journal articles

To see the other types of publications on this topic, follow the link: (+)-Digitoxigenin.

Journal articles on the topic '(+)-Digitoxigenin'

Author: Grafiati

Published: 4 June 2021

Last updated: 19 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic '(+)-Digitoxigenin.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Drakenberg, Torbjörn, Peter Brodelius, Deane D. McIntyre, and Hans J. Vogel. "Structural studies of digitoxin and related cardenolides by two-dimensional NMR." Canadian Journal of Chemistry 68, no. 2 (1990): 272–77. http://dx.doi.org/10.1139/v90-037.

Full text

Abstract:

The 1H and 13C NMR spectra of the cardenolides digitoxigenin, digoxigenin, digitoxin, and mono- and bis-digitoxigenin digitoxosides have been completely assigned by two-dimensional NMR spectroscopy. The techniques used include phase-sensitive COSY, multiple relay COSY, and carbon–proton correlation (HETCOR and HMQC) spectra. Various aspects of the solution conformation of the steroid moiety of digitoxin and digoxigenin could be determined from coupling constants and NOE difference experiments and they are indicative of an all-chair conformation. The carbohydrate rings in digitoxin and the mono

APA, Harvard, Vancouver, ISO, and other styles

2

Jensen, Kjell Briseid. "Fluorimetric Determination of Digitoxigenin." Acta Pharmacologica et Toxicologica 9, no. 1 (2009): 66–74. http://dx.doi.org/10.1111/j.1600-0773.1953.tb02930.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Kutney, James P., Krystyna Piotrowska, John Somerville, Shyh-Pyng Huang, and Steven J. Rettig. "The chemistry of thujone. XIII. Synthetic studies in the digitoxigenin series." Canadian Journal of Chemistry 67, no. 4 (1989): 580–89. http://dx.doi.org/10.1139/v89-088.

Full text

Abstract:

The thujone-derived chiral synthon 1 is converted, via selenium chmistry, to the important cross-conjugated dienone 2 and the latter is then convertible to the unsaturated cardenolide analogue 3, which through known methodology (3 → 26 → 27 → 4), completes a formal synthesis of digitoxigenin (4). Extensive studies to afford 2 from androstenedione (5) are also described and a new approach to elaborate the essential butenolide ring system, characteristic of the cardiac active steroids, is developed. Keywords: thujone, steroid synthesis, digitoxigenin.

APA, Harvard, Vancouver, ISO, and other styles

4

Honma, Masahiro, and Masahisa Nakada. "Enantioselective total synthesis of (+)-digitoxigenin." Tetrahedron Letters 48, no. 9 (2007): 1541–44. http://dx.doi.org/10.1016/j.tetlet.2007.01.024.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Pádua, Rodrigo M., Alaíde B. Oliveira, José D. Souza Filho, Jacqueline A. Takahashi, Maurício de Abreu e. Silva, and Fernão C. Braga. "Biotransformation of digitoxigenin by Cochliobolus lunatus." Journal of the Brazilian Chemical Society 18, no. 7 (2007): 1303–10. http://dx.doi.org/10.1590/s0103-50532007000700002.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Pádua, Rodrigo M., Alaíde B. Oliveira, José D. Souza Filho, Géssy J. Vieira, Jacqueline A. Takahashi, and Fernão C. Braga. "Biotransformation of digitoxigenin by Fusarium ciliatum." Journal of the Brazilian Chemical Society 16, no. 3b (2005): 614–19. http://dx.doi.org/10.1590/s0103-50532005000400019.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Prisbe, Ernest J., Julien P. H. Verheyden, Wayne W. Montgomery, and Arthur M. Strosberg. "Digitoxigenin 3-O-.beta.-D-furanosides." Journal of Medicinal Chemistry 29, no. 2 (1986): 239–44. http://dx.doi.org/10.1021/jm00152a012.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Fu, Yu Wan, Hua Sun, Yan Jun Shen, Xi Chen, and Min Wang. "Biotransformation of Digitoxin by Aspergillus Ochraceus." Advanced Materials Research 343-344 (September 2011): 1281–84. http://dx.doi.org/10.4028/www.scientific.net/amr.343-344.1281.

Full text

Abstract:

Biotransformations of natural products have great potential for preparation of lead compounds. In this paper, the biotransformation of digitoxin (1) with Aspergillus ochraceus afforded two products, identified as digitoxigenin (2) and sarmentogenin (3) by HR-MS, 1H-NMR and 13C-NMR.

APA, Harvard, Vancouver, ISO, and other styles

9

Honma, Masahiro, and Masahisa Nakada. "Corrigendum to “Enantioselective total synthesis of (+)-digitoxigenin”." Tetrahedron Letters 48, no. 12 (2007): 2217. http://dx.doi.org/10.1016/j.tetlet.2007.01.109.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Kawaguchi, Kiichiro, Takashi Watanabe, Masao Hirotani, and Tsutomu Furuya. "Biotransformation of digitoxigenin by cultured ginseng cells." Phytochemistry 42, no. 3 (1996): 667–69. http://dx.doi.org/10.1016/0031-9422(96)00079-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Feng, Xinchi, Cuifen Wang, Yunhui Xu, et al. "Topical Digitoxigenin for Wound Healing: A Feasibility Study." Bioengineering 5, no. 1 (2018): 21. http://dx.doi.org/10.3390/bioengineering5010021.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Kawaguchi, Kiichiro, Sachiko Koike, Masao Hirotani, et al. "Biotransformation of digitoxigenin by cultured Strophanthus hybrid cells." Phytochemistry 47, no. 7 (1998): 1261–65. http://dx.doi.org/10.1016/s0031-9422(97)00748-6.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Stork, Gilbert, Fred West, Hee Yoon Lee, Richard C. A. Isaacs, and Shino Manabe. "The Total Synthesis of a Natural Cardenolide: (+)-Digitoxigenin." Journal of the American Chemical Society 118, no. 43 (1996): 10660–61. http://dx.doi.org/10.1021/ja962163m.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Scharfenberg-Pfeiffer, D., E. Höhne, and M. Wunderwald. "Crystal- and molecular structure of 19-nor-digitoxigenin." Crystal Research and Technology 22, no. 11 (1987): 1403–8. http://dx.doi.org/10.1002/crat.2170221109.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Kawaguchi, Kiichiro, Masao Hirotani, Takafumi Yoshikawa, and Tsutomu Furuya. "Biotransformation of digitoxigenin by ginseng hairy root cultures☆." Phytochemistry 29, no. 3 (1990): 837–43. http://dx.doi.org/10.1016/0031-9422(90)80029-g.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Fenster, P. E., R. T. MacFarland, P. E. Graves, D. Perrier, and F. I. Marcus. "Bioavailability of the bis- and monodigitoxosides of digitoxigenin." European Journal of Clinical Pharmacology 28, no. 6 (1985): 649–52. http://dx.doi.org/10.1007/bf00607909.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Vaněk, T., T. Macek, and J. Harmatha. "Glucosidation of digitoxigenin by tissue culture ofDigitalis lanata." Biotechnology Letters 8, no. 12 (1986): 859–62. http://dx.doi.org/10.1007/bf01078645.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Daniewski, Andrzej Robert, Marek Michal Kabat, Marek Masnyk, Wanda Wojciechowska та Jerzy Wicha. "New way to digitoxigenin from 3β-acetoxy-5-androsten-17-one. Stereoselective free radical substitution of iodide atom by nitrile group as a key step". Collection of Czechoslovak Chemical Communications 56, № 5 (1991): 1064–69. http://dx.doi.org/10.1135/cccc19911064.

Full text

Abstract:

Digitoxigenin (I) was obtained from 17-oxoandrost-5-en-3β-yl acetate (III) using, as a key step, free radical stereoselective substitution of an iodine atom in VI by a nitrile group. Transformation of the nitrile group at C-17 into a pregnane side chain or a butenolide lactone ring took place without isomerization at C-17.

APA, Harvard, Vancouver, ISO, and other styles

19

Beaubien, Sylvie, та Pierre Deslongchamps. "Total synthesis of 14β-fluorosteroids via a transannular DielsAlder reaction". Canadian Journal of Chemistry 84, № 1 (2006): 29–48. http://dx.doi.org/10.1139/v05-259.

Full text

Abstract:

14β-Fluorosteroids 3 and 4 were synthesized to give a new class of unnatural cardenolides. The total synthesis of racemic 14β-fluorosteroids was accomplished using a highly diastereoselective transannular DielsAlder reaction on a trans-cis-cis macrocyclic triene. The α-fluoro analog 4 provided a comparable inhibitory activity to natural digitoxigenin 1.Key words: fluorosteroid, bioisostere, cardiovascular diseases, transannular DielsAlder reaction (TADA), macrocyclization.

APA, Harvard, Vancouver, ISO, and other styles

20

Munkert, Jennifer, Eliza R. Gomes, Lucas L. Marostica, et al. "New 99mTc-Labeled Digitoxigenin Derivative for Cancer Cell Identification." ACS Omega 4, no. 26 (2019): 22048–56. http://dx.doi.org/10.1021/acsomega.9b03167.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Warwick, Robert O., Mary P. Smith, Marta A. Graffy, and Gary L. Lage. "Altered distribution and toxicity of digitoxigenin in fasted mice." Life Sciences 37, no. 8 (1985): 775–82. http://dx.doi.org/10.1016/0024-3205(85)90548-x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Zhang, Jianjun, Larissa V. Ponomareva, Nitin S. Nandurkar, et al. "Influence of Sugar Amine Regiochemistry on Digitoxigenin Neoglycoside Anticancer Activity." ACS Medicinal Chemistry Letters 6, no. 10 (2015): 1053–58. http://dx.doi.org/10.1021/acsmedchemlett.5b00120.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

STORK, G., F. WEST, H. Y. LEE, R. C. A. ISAACS, and S. MANABE. "ChemInform Abstract: Total Synthesis of a Natural Cardenolide: (+)-Digitoxigenin (XIV)." ChemInform 28, no. 7 (2010): no. http://dx.doi.org/10.1002/chin.199707213.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Furuya, Tsutomu, Kiichiro Kawaguchi, and Masao Hirotani. "Biotransformation of digitoxigenin by cell suspension cultures of Strophanthus gratus." Phytochemistry 27, no. 7 (1988): 2129–33. http://dx.doi.org/10.1016/0031-9422(88)80110-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Kawaguchi, Kiichiro, Masao Hirotani, and Tsutomu Furuya. "Biotransformation of digitoxigenin by cell suspension cultures of Strophanthus amboensis." Phytochemistry 27, no. 11 (1988): 3475–79. http://dx.doi.org/10.1016/0031-9422(88)80751-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Kawaguchi, Kiichiro, Masao Hirotani, and Tsutomu Furuya. "Biotransformation of digitoxigenin by cell suspension cultures of Strophanthus intermedius." Phytochemistry 28, no. 4 (1989): 1093–97. http://dx.doi.org/10.1016/0031-9422(89)80190-6.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Kawaguchi, Kiichiro, Masao Hirotani, and Tsutomu Furuya. "Biotransformation of digitoxigenin by cell suspension cultures of Strophanthus divaricatus." Phytochemistry 30, no. 5 (1991): 1503–6. http://dx.doi.org/10.1016/0031-9422(91)84197-z.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Pouzar, Vladimír, Ivan Černý, Pavel Drašar, and Miroslav Havel. "New method of preparation of cardioglycoside hemisuccinates." Collection of Czechoslovak Chemical Communications 51, no. 9 (1986): 2019–28. http://dx.doi.org/10.1135/cccc19862019.

Full text

Abstract:

An indirect method for preparation of hemisuccinates (hydrogen butanedioates) is described, consisting in reaction of hydroxy derivatives with 2-(trimethylsilyl)ethyl hemisuccinate (I) followed by removal of the 2-(trimethylsilyl)ethyl group from the mixed succinate with tetrabutylammonium fluoride. It has been applied to the synthesis of hemisuccinates derived from cholesterol (II), (20E)-21-methoxycarbonylpregna-5,20-dien-3β-ol (V), digitoxigenin (XII), digitoxin (XV) and digoxin (XVIII). The method, however, is not suitable for the preparation of estrone hemisuccinate X which is cleaved wit

APA, Harvard, Vancouver, ISO, and other styles

29

Černý, Ivan, Petr Novotný, Pavel Drašar, Miroslav Havel та Josef Pacák. "Glycosylation of steroids with silver silicate and 2-deoxy-2-fluoro-α-D-glucopyranosyl bromide triacetate". Collection of Czechoslovak Chemical Communications 54, № 10 (1989): 2775–83. http://dx.doi.org/10.1135/cccc19892775.

Full text

Abstract:

Glycosylation with the title glycosyl bromide I in 1,2-dichloroethane in the presence of silver silicate and a molecular sieves afforded mixtures of 3,4,6-tri-O-acetyl-2-deoxy-2-fluoro-α- and β-D-glucopyranosides (V-X), derived from ethyl (20E)-3β-hydroxy-24-nor-5,20(22)-choladien-23-oate (II), (20E)-3β-hydroxy-5β-pregn-20-ene-21-carboxylate (III) and 3β, 14-dihydroxy-5β, 14β-card-20(22)-enolide (IV, digitoxigenin), in which the β-anomers predominated. Separation and deacetylation furnished the corresponding 2-deoxy-2-fluoroglucosides XI-XVI.

APA, Harvard, Vancouver, ISO, and other styles

30

Harkiss, K. J., P. A. Linley, and M. K. M. Mesbah. "Biotransformation of (23-14C)-Digitoxigenin and (23-14C)-Digitoxin inConvallaria majalisL." International Journal of Crude Drug Research 24, no. 1 (1986): 25–30. http://dx.doi.org/10.3109/13880208609060883.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Ramirez, Margarita, Leonardo Del Valle, Alicia Sanchez-Mendoza, Fermin Alejandro Tenorio, Gabriela Zarco, and Gustavo Pastelin. "Effect of the digitoxigenin derivative, INCICH-D7, on Na+, K+-ATPase." Biochemical Pharmacology 70, no. 6 (2005): 851–57. http://dx.doi.org/10.1016/j.bcp.2005.06.020.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Wang, Hua-Yu Leo, Bulan Wu, Qi Zhang, Sang-Woo Kang, Yon Rojanasakul та George A. O’Doherty. "C5′-Alkyl Substitution Effects on Digitoxigenin α-l-Glycoside Cancer Cytotoxicity". ACS Medicinal Chemistry Letters 2, № 4 (2011): 259–63. http://dx.doi.org/10.1021/ml100291n.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Boff, Laurita, Jennifer Munkert, Flaviano Melo Ottoni, et al. "Potential anti-herpes and cytotoxic action of novel semisynthetic digitoxigenin-derivatives." European Journal of Medicinal Chemistry 167 (April 2019): 546–61. http://dx.doi.org/10.1016/j.ejmech.2019.01.076.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Minuk, G. Y., A. Bennaroch, and L. X. Ding. "Polyamine transport systems in isolated rat hepatocytes derived from resting and regenerating livers." American Journal of Physiology-Gastrointestinal and Liver Physiology 263, no. 2 (1992): G169—G173. http://dx.doi.org/10.1152/ajpgi.1992.263.2.g169.

Full text

Abstract:

Polyamines and their principal metabolite, gamma-aminobutyric acid (GABA), modulate eukaryotic cell growth. To determine whether the liver possesses specific polyamine transport sites and whether changes occur to these or GABA transport sites during hepatic regeneration, suspensions of rat hepatocytes derived from in situ collagenase perfusions of livers at times 0, 24, 48, and 72 h post-partial hepatectomy were incubated at 4, 20, and 37 degrees C with various concentrations of the following ligands: [3H]putrescine, [3H]spermidine, [14C]spermine, and [3H]GABA together with or without excess u

APA, Harvard, Vancouver, ISO, and other styles

35

YAMAKI, Hideaki, Akihiro NONAKA, Moritaka TANI, and Mitsuaki WATANABE. "GC/MS Analysis for Strophanthidin and Digitoxigenin in "Moroheiya"(Corchorus olitorius L.)." NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI 46, no. 4 (1999): 255–61. http://dx.doi.org/10.3136/nskkk.46.255.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Scharfenberg-Pfeiffer, D., E. Höhne, R. Megges, and H. J. Schmidt. "Crystal and molecular structure of 14-desoxy-14ß-azido-digitoxigenin-3-acetate." Crystal Research and Technology 23, no. 6 (1988): 815–20. http://dx.doi.org/10.1002/crat.2170230620.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

GODA, Yukihiro, Shinobu SAKAI, Takatoshi NAKAMURA, Kazunari KONDO, Hiroshi AKIYAMA, and Masatake TOYODA. "Determination of Digitoxigenin Glycosides in “Moroheiya” (Corchorus olitorius) and Its Products by HPLC." Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi) 39, no. 6 (1998): 415–20. http://dx.doi.org/10.3358/shokueishi.39.6_415.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

FUJII, Youichi, Masahiro FUJII, Yukari IKEDA, Mayumi MORITA, and Mitsuru YAMAZAKI. "Biological Sciences and Analytical Chemistry. Preparation of antiserum for radioimmunoassay of digitoxigenin bisdigitoxoside." Bunseki kagaku 44, no. 10 (1995): 859–64. http://dx.doi.org/10.2116/bunsekikagaku.44.859.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Johannes, Andrea, Lutz von Meyerinck, and Achim Schmoldt. "Purification of a rat liver cytosolic sulfotransferase responsible for the conjugation of digitoxigenin." Biochemical Pharmacology 39, no. 2 (1990): 301–7. http://dx.doi.org/10.1016/0006-2952(90)90029-k.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Bohl, Martin, and Zeno Simon. "MTD Approach to Quantitative Structure-Activity Relationships for Cardiotonic Steroids." Zeitschrift für Naturforschung C 40, no. 11-12 (1985): 858–62. http://dx.doi.org/10.1515/znc-1985-11-1219.

Full text

Abstract:

Abstract A minimal topological difference (MTD) approach is made to describe quantitative structure-activity relationships (OSAR) for the Na+, K+-ATPase inhibitory activity of cardiotonic steroids. The calculations take into account 20 derivatives of digitoxigenin, digoxigenin, and gitoxigenin with small substituents at different sites of the steroid backbone. A multiple correlation coefficient of r = 0.916 is obtained using the MTD and an indicator variable for the presence of a 15β substituent. The corresponding receptor map reveals receptor wall vertices in the C11 , C12, C15, and C22 regio

APA, Harvard, Vancouver, ISO, and other styles

41

Go, K., and K. K. Bhandary. "Structural studies on the biosides of Digitalis lanata: bisdigitoxosides of digitoxigenin, gitoxigenin and digoxigenin." Acta Crystallographica Section B Structural Science 45, no. 3 (1989): 306–12. http://dx.doi.org/10.1107/s0108768189001734.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Hinds, John W., Sean B. McKenna, Ehesan U. Sharif, Hua-Yu L. Wang, Novruz G. Akhmedov та George A. O'Doherty. "C3′/C4′-Stereochemical Effects of Digitoxigenin α-L-/α-D-Glycoside in Cancer Cytotoxicity". ChemMedChem 8, № 1 (2012): 63–69. http://dx.doi.org/10.1002/cmdc.201200465.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

OGAWA, Masahiko, Katuhiro HAYASI, Satoko TOMIMORI, Nobuyuki KONISHI, and Osamu NAKAYAMA. "Contents of Strophanthidin Glycosides and Digitoxigenin Glycosides in "Moroheiya" (Corchorus olitorius L.) and Its Products." NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI 49, no. 4 (2002): 282–87. http://dx.doi.org/10.3136/nskkk.49.282.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Boff, Laurita, Lara Persich, Paula Brambila, et al. "Investigation of the cytotoxic activity of two novel digitoxigenin analogues on H460 lung cancer cells." Anti-Cancer Drugs 31, no. 5 (2020): 452–62. http://dx.doi.org/10.1097/cad.0000000000000872.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Go, K., and K. K. Bhandary. "Structural studies on the biosides of Digitalis lanata: bisdigitoxosides of digitoxigenin, gitoxigenin and digoxigenin. Erratum." Acta Crystallographica Section B Structural Science 46, no. 2 (1990): 288. http://dx.doi.org/10.1107/s0108768190099955.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Lowndes, Joseph M., Mabel Hokin-Neaverson, and Arnold E. Ruoho. "Photoaffinity labeling of erythrocyte membrane (Na+ + K+)-ATPase with high specific activity [125I]iodoazidogalactosyl digitoxigenin." Biochimica et Biophysica Acta (BBA) - Biomembranes 904, no. 1 (1987): 154–58. http://dx.doi.org/10.1016/0005-2736(87)90098-8.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Radenkova-Saeva, J., and P. Atanasov. "Cardiac Glycoside Plants Self-Poisoning." Acta Medica Bulgarica 41, no. 1 (2014): 99–104. http://dx.doi.org/10.2478/amb-2014-0013.

Full text

Abstract:

Summary Cardiac glycosides are found in a diverse group of plants including Digitalis purpurea and Digitalis lanata (foxgloves), Nerium oleander, Convallaria majalis (lily of the valley), Strophanthus gratus, etc. Nerium Oleander is an indoor and ornamental plant of an evergreen shrub. It’s widespread in countries with a Mediterranean climate. Oleander is one of the most poisonous plants known to humans. All parts of the nerium oleander are poisonous, primarily due to the contained cardiac glycosides - oleandrin, nerin, digitoxigenin, and olinerin of which oleandrin is the principal toxin. The

APA, Harvard, Vancouver, ISO, and other styles

48

Petersen, Maike, Hanns Ulrich Seitz та Ernst Reinhard. "Characterization and Localization of Digitoxin 12 β-Hydroxylase from Cell Cultures of Digitalis lanata EHRH". Zeitschrift für Naturforschung C 43, № 3-4 (1988): 199–206. http://dx.doi.org/10.1515/znc-1988-3-409.

Full text

Abstract:

The cytochrome P-450-dependent monooxygenase digitoxin 12β-hydroxylase from cell cultures of Digitalis lanata needs NADPH and molecular oxygen and hydroxylates cardiac glycosides with the aglycon of digitoxigenin to the corresponding derivatives of the C-series. Other electron donors cannot replace NADPH. The apparent Km-values are 26 μᴍ for NADPH, 7.1 μᴍ for β-methyldigitoxin and 10 μᴍ for digitoxin. The reaction is inhibited by NADP+ and cytochrome c in a competitive mode. The optimum temperature was at 20 °C. Low concentrations of Mn2+, Mg2+, and EDTA were slightly stimulatory, but there wa

APA, Harvard, Vancouver, ISO, and other styles

49

YAMAUCHI, TATSUO, FUMIKO ABE, and ALFRED S. C. WAN. "Studies on Cerbera. V. Minor glycosides of 17.ALPHA.-digitoxigenin from the stems of genus Cerbera." CHEMICAL & PHARMACEUTICAL BULLETIN 35, no. 12 (1987): 4993–95. http://dx.doi.org/10.1248/cpb.35.4993.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Theurer, Christoph, Wolfgang Kreis, and Ernst Reinhard. "Effects of Digitoxigenin, Digoxigenin, and Various Cardiac Glycosides on Cardenolide Accumulation in Shoot Cultures ofDigitalis lanata." Planta Medica 64, no. 08 (1998): 705–10. http://dx.doi.org/10.1055/s-2006-957562.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!