Log in

Relevant bibliographies by topics / Dimethyl derivative / Journal articles

To see the other types of publications on this topic, follow the link: Dimethyl derivative.

Journal articles on the topic 'Dimethyl derivative'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Dimethyl derivative.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Lee, Seol, YongJae Cho, and Kee Hag Lee. "Five Regioisomers of Dimethyl Dodecahedrane Derivatives: A Hybrid DFT B3LYP Study." Journal of Chemistry 2017 (2017): 1–7. http://dx.doi.org/10.1155/2017/5494038.

Full text

Abstract:

The hybrid density functional (B3LYP/6-31G(d, p)) method was used to understand why 1,2-dimethyl dodecahedrane has not been reported yet. From the direct dimethyl substitution of the dodecahedrane cage, we could have five C20H18(CH3)2 derivatives which were geometrically optimized without constraints. The results suggest that 1,16-dimethyl dodecahedrane derivative is the most stable, whereas the 1,2-dimethyl derivative is the most unstable; this implies that the distortion due to steric hindrance interactions would be a crucial effect on the relative energies of the dimethyl dodecahedranes. It

APA, Harvard, Vancouver, ISO, and other styles

2

Rádl, Stanislav, and Viktor Zikán. "Synthesis of 1,2, and 9-methyl derivatives of 4,9-dihydro-6-methoxy-3-methyl-4-oxo-1H(2H)-pyrazolo[3,4-b]quinoline and 4,9-dihydro-6-hydroxy-3-methyl-4-oxo-1H(2H)-pyrazolo[3,4-b]quinoline and their antiviral activity." Collection of Czechoslovak Chemical Communications 52, no. 3 (1987): 788–92. http://dx.doi.org/10.1135/cccc19870788.

Full text

Abstract:

The paper describes syntheses of 4,9-dihydro-6-methoxy-3-methyl-4-oxo-1H(2H)-pyrazolo[3,4-b]quinoline (Ia), its 1-methyl derivative (Ic), 1,9-dimethyl derivative (Ie), 2-methyl derivative (IIa), and 2,9-dimethyl derivative (IIc). Demethylation of these compounds with hydrobromic acid afforded 4,9-dihydro-6-hydroxy-3-methyl-4-oxo-1H(2H)-pyrazolo[3,4-b]quinoline (Ib), its 1-methyl derivative (Id), 1,9-dimethyl derivative (If), 2-methyl derivative (IIb), and 2,9-dimethyl derivative (IId) respectively. 4,9-Dihydro-6-hydroxy-3,9-dimethyl-4-oxo-1H-pyrazolo[3,4-b]quinoline (Ig) was prepared by demeth

APA, Harvard, Vancouver, ISO, and other styles

3

Di Paolo, Matias, Mariano L. Bossi, Ricardo Baggio, and Sebastián A. Suarez. "Two rhodamine 6G derivative compounds: a structural and fluorescence single-crystal study." Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials 72, no. 5 (2016): 684–92. http://dx.doi.org/10.1107/s2052520616009343.

Full text

Abstract:

The synthesis, characterization, structural analysis and fluorescence properties of two rhodamine 6G derivatives are described, namely a propargylamine derivative, 3′,6′-bis(ethylamino)-2′,7′-dimethyl-2-(methylcyanide)spiro[isoindole-1,9′-xanthen]-3(2H)-one (I), and a γ-aminobutyric acid (GABA) derivative, 3′,6′-bis(ethylamino)-2′,7′-dimethyl-3-oxospiro[isoindole-1,9′-xanthen]-2(3H)-yl)butyricacid (II). Both structures are compared with four similar ones from the Cambridge Structural Database (CSD), and the interactions involved in the stabilization are analyzed using the atoms in molecules (A

APA, Harvard, Vancouver, ISO, and other styles

4

Plešek, Jaromír, Farzaneh Hosseinpour Rajabi, Veena Vangani та Jiří Fusek. "Constitution and Properties of the 8,8'-μ-(H2NO)=(1,2-C2B9H10)2-3-Co Bridged Cobaltaborane". Collection of Czechoslovak Chemical Communications 59, № 6 (1994): 1326–36. http://dx.doi.org/10.1135/cccc19941326.

Full text

Abstract:

Constitution of 8,8'-μ-H2N(-O-)(1,2-C2B9H10)2-3-Co sandwich has been elucidated 17 years after its first synthesis, via high resolution NMR methods supplemented by mass spectrometry. The species gives relevant "oximes" with acetone and benzaldehyde and is quantitatively methylated to the N,N'-dimethyl derivative, which shows an interesting redox disproportionation to a triatomically bridged sandwich with a 8,8'-μ-O-CH=N(Me)- bridge between both ligands. Several other "peculiar" reactions of this dimethyl derivative are discussed. On reductive cleavage of the parent hydroxylamine the non-bridge

APA, Harvard, Vancouver, ISO, and other styles

5

Rádl, Stanislav, Lenka Kovářová, and Jiří Holoubek. "Synthesis and antibacterial activity of some 1-(2-propynyl) and 1-propadienyl derivatives of 1,4-dihydro-4-oxoquinoline-3-carboxylic acids and similar heterocycles." Collection of Czechoslovak Chemical Communications 56, no. 2 (1991): 439–48. http://dx.doi.org/10.1135/cccc19910439.

Full text

Abstract:

N-Alkylation of IIIa, IIIb, IIId - IIIf and 9-acridanone with 3-bromopropyne in dimethyl sulfoxide in the presence of potassium carbonate yielded N-(2-propynyl) derivatives IVa - IVe and VIa, respectively. Ethyl esters IVa, IVb, and IVe were hydrolyzed to IVf - IVh, respectively. Compounds IVf, IVg, IVctreated with bases yielded N-propadienyl derivatives Va - Vc. On the other hand 2-substituted compounds IVd and IVh did not change under the same conditions. Compound VIa treated with powdered potassium hydroxide in dimethyl sulfoxide at room temperature yielded N-(1-propynyl) derivative VII.

APA, Harvard, Vancouver, ISO, and other styles

6

Musgrave, RP, NW Jacobsen, G. Bourne, CHL Kennard, G. Smith, and TCW Mak. "Cycloaddition Reactions of 3-Dimethylamino-1-methyl-1,2,4-triazinium-5-olates With Dimethyl Acetylenedicarboxylate." Australian Journal of Chemistry 48, no. 6 (1995): 1175. http://dx.doi.org/10.1071/ch9951175.

Full text

Abstract:

The cycloaddition reactions of some 3-dimethylamino-1-methyl-1,2,4-triazinium-5-olates (1) with dimethyl acetylenedicarboxylate ( dmad ) were studied. The products in all cases were found tobe dimethyl 4-dimethylamino-1-methyl-6-oxo-1,3a,6,6a-tetrahydropyrrolo[3,4-c]pyrazole-3,3a-dicarboxylate derivatives (2). The structure determinations were carried out by 1H and 13C n.m.r. and mass spectrometry, and for one derivative by single-crystal X-ray diffractometry. The mechanism of the reaction is also discussed.

APA, Harvard, Vancouver, ISO, and other styles

7

Rádl, Stanislav, Viktor Zikán, and František Šmejkal. "Syntheses of 1, 2, and 9-methyl derivatives of 4,9-dihydro-3-methyl-4-oxo-1H(2H)-pyrazolo[3,4-b]quinoline and their antiviral activity." Collection of Czechoslovak Chemical Communications 50, no. 5 (1985): 1057–63. http://dx.doi.org/10.1135/cccc19851057.

Full text

Abstract:

The paper describes syntheses of 4,9-dihydro-3-methyl-4-oxo-1H(2H)-pyrazolo[3,4-b]quinoline (Ia), its 1-methyl derivative (Ib), 2-methyl derivative (IIa), 9-methyl derivative (Ic), 1,9-dimethyl derivative (Id) and 2,9-dimethyl derivative (IIb). Sodium salts of compounds Ia, Ib, Ic and IIa were methylated with methyl iodide in dimethylformamide at room temperature, compounds Id and IIb were demethylated with pyridine hydrochloride. The compounds prepared were tested for antiviral activity in vivo in mice against influenza virus A2-Hongkong and the Encephalomyocarditis virus.

APA, Harvard, Vancouver, ISO, and other styles

8

Cambie, RC, PS Rutledge, RJ Stevenson, and PD Woodgate. "Synthesis of Phthalide Derivatives of Podocarpic Acid Via Directed ortho Metalation: a Route to Highly Substituted Octahydrochrysene Derivatives." Australian Journal of Chemistry 47, no. 5 (1994): 913. http://dx.doi.org/10.1071/ch9940913.

Full text

Abstract:

Two phthalide derivatives (7) and (8) have been prepared from podocarpic acid (1) via directed ortho metallation. The ring-c aromatic 16-oxa-17-oxo androstane analogue (8) was reacted with dimethyl acetylenedicarboxylate to give the 1,4-epoxy decahydrochrysene derivatives (9) and (10). The stereoisomer (10) was aromatized under acidic conditions to give the chrysen-1-ol derivative (11).

APA, Harvard, Vancouver, ISO, and other styles

9

Rádl, Stanislav, and Viktor Zikán. "Syntheses of some 4-dialkylaminoalkylamino derivatives of 2,3-dimethyl-2H- and 3,9-dimethyl-9H-pyrazolo[3,4-b]quinoline." Collection of Czechoslovak Chemical Communications 51, no. 8 (1986): 1692–97. http://dx.doi.org/10.1135/cccc19861692.

Full text

Abstract:

Reactions of 4-chloro-2,3-dimethyl-2H-pyrazolo[3,4-b]quinoline and 4-chloro-6-methoxy-2,3-dimethyl-2H-pyrazolo[3,4-b]quinoline with 3-dimethylaminopropylamine and/or 2-dimethylaminoethylamine afforded 4-(3-dimethylaminopropylamino)-2,3-dimethyl-2H-pyrazolo[3,4-b]quinoline (IIa), its 6-methoxy derivative (IIc), 4-(2-diethylaminoethylamino)-2,3-dimethyl-2H-pyrazolo[3,4-b]quinoline (IIb) and its 6-methoxy derivative (IId). Reaction of 4,9-dihydro-3,9-dimethyl-4-oxo-1H-pyrazolo[3,4-b]quinoline with thionyl chloride gave an intermediate, whose reaction with 3-dimethylaminopropylamine afforded 4-(3-

APA, Harvard, Vancouver, ISO, and other styles

10

Kmal, Rafid Q., Shaimaa A. Behget, and Meaad N. Husean. "Synthesis and Characterization of Formazan Derivatives from Schiff’s Base and Studying their Biological Activity." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 12, no. 02 (2022): 782–88. http://dx.doi.org/10.25258/ijddt.12.2.56.

Full text

Abstract:

A group of substituted formazine derivatives was prepared through several steps where the first step was the preparation of compound (1) by reacting chloroacetyl chloride with 2-aminopyrimidine, and the second step was the reaction of compound (1) with hydrazine hydrate to obtain the derivative (2) and in the third step was prepared Schiff’s base (3) by reaction of derivative (2) with para-dimethyl benzaldehyde and then a number of formazine derivatives were synthesized by reaction of derivative (3) with a number of substituted aromatic amines. The newly prepared derivatives are distinguished

APA, Harvard, Vancouver, ISO, and other styles

11

Journal, Baghdad Science. "Synthesis of New Heterocyclic Derivatives from 4-(3, 5-Dimethyl-1-phenyl-1H-pyrazol-4-ylazo)- benzoic acid." Baghdad Science Journal 7, no. 1 (2010): 727–36. http://dx.doi.org/10.21123/bsj.7.1.727-736.

Full text

Abstract:

In this work pyrazolin derivatives were prepared from the diazonium chloride salt of 4-aminobenzoic acid. Azo compounds were prepared from the reaction of an ethanolic solution of sodium acetate and calculated amount of active methylene compound namely, acetyl acetone to obtain the corresponding hydrazono derivative (1). Cyclocondensation reaction of compounds (1) with hydrazine hydrate and phenyl hydrazine in boiling ethanol affording the corresponding pyrazoline-5-one derivatives of 4-aminobenzoic acid (2,3). Then compound (3) was reacted with thionyl chloride to give the corresponding acid

APA, Harvard, Vancouver, ISO, and other styles

12

Knörzer, Gabriele, Hermann Seyffer, Hans Pritzkow, and Walter Siebert. "Neuartige Allylboran- und Allyldiboran(4)-Derivate / Novel Allylboran- and Allyldiboran(4) Derivatives." Zeitschrift für Naturforschung B 45, no. 7 (1990): 985–88. http://dx.doi.org/10.1515/znb-1990-0712.

Full text

Abstract:

Allyldiboran(4) derivatives la—c are obtained from allylmagnesium chloride and chloro derivatives of diboran(4). la—c are air-sensitive liquids; heating of le did not yield a 2,3-dihydro-l,2-diborole derivative (B). Reaction between 1,1-bis(dichloroboryl)-3,3-dimethyl-butane (5) and H2C=C(CH2SnMe3)2 (4) leads to the heat-sensitive chloro derivative 2a, in which the chlorine is substituted by Me3SiNMe2 to give stable 1,3-bis-dimethylamino-5-methylene-2-neopentyl- 1,3-diborinane (2 b). 1,2-Bis(dichloroboryl)benzene and 4 yield the chloro derivative 3a, and its substitution with HN(i-Pr)2 leads t

APA, Harvard, Vancouver, ISO, and other styles

13

Sleziak, Róbert, and Alžbeta Krutošíková. "Cycloaddition Reactions of Furo[2,3-b]pyrroles." Collection of Czechoslovak Chemical Communications 64, no. 2 (1999): 321–28. http://dx.doi.org/10.1135/cccc19990321.

Full text

Abstract:

Reactions of furo[2,3-b]pyrroles with dimethyl butynedioate and ethyl propynoate were investigated. The reaction course is influenced by the substituents on the fused system. Products of [4+2]cycloaddition to the furan ring leading to indole derivatives have been observed. In the case of the reaction of methyl 6H-furo[2,3-b]pyrrole-5-carboxylate (1a) with dimethyl butynedioate, products of [4+2]cycloaddition to the furan ring as well as of Michael addition to the pyrrole ring leading to N-substituted indole derivative 3 have been observed.

APA, Harvard, Vancouver, ISO, and other styles

14

Hanna, Naeem B., Milena Masojídková, and Alois Pískala. "Synthesis and Biological Activity of N4-Methyl-5-azacytidines." Collection of Czechoslovak Chemical Communications 63, no. 5 (1998): 713–22. http://dx.doi.org/10.1135/cccc19980713.

Full text

Abstract:

Protected N4-methyl and N4,N4-dimethyl derivatives of 5-azacytidine 3 and 4 were prepared by selective aminolysis of benzoylated 4-methoxy-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one 5, by glycosylation of silylated N4-methyl- or N4,N4-dimethyl-5-azacytosines 7 and 8 with 2,3,5-tri-O-benzoyl-α,β-D-ribofuranosyl chloride (11) or by several modifications of the isocyanate method. By the isocyanate approach, also the α-D anomer of protected N4-methyl-5-azacytidine 17 was obtained as a minor product. The protected dimethyl derivative 4 was also obtained by the reaction of isobiuret 22 with dimet

APA, Harvard, Vancouver, ISO, and other styles

15

Avendaño, Carmen, María Teresa Ramos, José Elguero, María Luisa Jimeno, Juana Bellanato, and Feliciana Florencio. "Tautomerism of bis(2-benzothiazolyl)methanes." Canadian Journal of Chemistry 66, no. 6 (1988): 1467–73. http://dx.doi.org/10.1139/v88-236.

Full text

Abstract:

Tautomerism of dibenzothiazolylmethane (1) and its C-methyl derivative (2) has been studied by 1H nuclear magnetic resonance, ultraviolet, and infrared spectroscopy using C,C-dimethyl (3) and N-methyl (4) derivatives as model compounds of the "CH" and "NH" forms, respectively. X-ray diffraction analysis of the "fixed" N-methyl derivative 4 shows that it corresponds to the Z-sE isomer 4b2. The CH tautomers are unstable in solution and they slowly isomerize into a mixture of NH tautomers that depends on the solvent and on the C-substituent (H or CH3).

APA, Harvard, Vancouver, ISO, and other styles

16

Canudas, Nieves, Manuel Moreno, Sara Pekerar, Carlos Gámez, Estefania Sucre, and José E. Villamizar. "New Z-chalcones obtained from aloe-emodin: Synthesis, characterization and photophysical properties." Journal of Chemical Research 43, no. 3-4 (2019): 101–6. http://dx.doi.org/10.1177/1747519819841822.

Full text

Abstract:

Three new Z-chalcone derivatives were synthesized under stereoselective conditions by condensation between an aldehyde derivative (prepared from aloe-emodin) and an acetophenone, using potassium hydroxide in dimethyl sulfoxide/H2O at room temperature. The Z configuration of the chalcone derivatives was established by nuclear magnetic resonance (NMR) studies. Photophysical properties related to the UV-Vis absorption/emission spectra and molar extinction coefficients (ε) in different solvents were determined.

APA, Harvard, Vancouver, ISO, and other styles

17

Rao, Guo-Wu, Jia-Bin Ni, and Qi Li. "Synthesis and Structure Analysis of N1,N4-di-tert-Butyl-3,6-Dimethyl-1,4-Dihydro-1,2,4,5-Tetrazine-1,4-Dicarboxamide." Journal of Chemical Research 36, no. 3 (2012): 172–74. http://dx.doi.org/10.3184/174751912x13305927311260.

Full text

Abstract:

N1, N4-Di- tert-butyl-3,6-dimethyl-1,4-dihydro-1,2,4,5-tetrazine-1,4-dicarboxamide was prepared from 3,6-dimethyl-1,6-dihydro-1,2,4,5-tetrazine, and its structure was confirmed by single-crystal X-ray diffraction. This reaction yields the 1,4-dicarboxamide derivative rather than the 1,2-dicarboxamide derivative. The central six-member ring of the title compound has a boat conformation and therefore, is not homoaromatic.

APA, Harvard, Vancouver, ISO, and other styles

18

Kantlehner, Willi, Erwin Haug, and Christophe Bauer. "Orthoamide und Iminiumsalze, LXXXI [1]. Orthoamid-Derivate der 1,3-Dimethylparabansäure / Orthoamides and Iminium Salts LXXXI [1]. Orthoamide Derivatives of 1,3-Dimethylparabanic Acid." Zeitschrift für Naturforschung B 67, no. 9 (2012): 907–12. http://dx.doi.org/10.5560/znb.2012-0123.

Full text

Abstract:

1,3-Dimethyl-5-imino-imidazolidine-2,4-dione (7a) undergoes thiolysis (H2S) to give the corresponding imidazolidine-2,4-dione-5-thione derivative 6. The 5-N-methylimino analogue 7b can be obtained from 7a by methylation. Further methylation of 7b affords the crude iminium salt 8c from which the heterocyclic orthoamide derivatives 10, 11 can be prepared. The heterocyclic amide acetal 9a can be obtained from 7a and dimethyl sulfate in methanol and subsequent addition of sodium methanolate in a one-pot reaction. The aminal ester 10 is converted to the amide acetal 9a on treatment with hydrogen ch

APA, Harvard, Vancouver, ISO, and other styles

19

Toman, Jaromír, and Jiří Klicnar. "Derivatives of 3,4-dihydro-3-thioxo-2-quinoxalinylacetic acid." Collection of Czechoslovak Chemical Communications 51, no. 2 (1986): 419–28. http://dx.doi.org/10.1135/cccc19860419.

Full text

Abstract:

Ethyl 3,4-dihydro-4-methyl-3-thioxo-2-quinoxalinylacetate has been prepared by thionation of the 3-oxo derivative. The mechanism is discussed of the reaction of this ester with diethylamine giving the two non-isomerizing ketimine-enamine tautomers and 1,2-dihydro-1,3-dimethyl-2-thioxoquinoxaline. Structure has been studied of the reaction product of both this derivative and its 3-oxo analogue with sodium hydride in dimethyl sulphoxide.

APA, Harvard, Vancouver, ISO, and other styles

20

Šindelář, Karel, Vladimír Valenta, Jiří Holubek, Oluše Matoušová, and Miroslav Protiva. "Potential antidepressants. Synthesis of 6,11-dihydrodibenzo[b,e]thiepin-11-yl (dimethylaminomethyl)phenyl ethers, sulfides, amines and some related compounds." Collection of Czechoslovak Chemical Communications 55, no. 1 (1990): 282–95. http://dx.doi.org/10.1135/cccc19900282.

Full text

Abstract:

Reactions of 11-chloro-6,11-dihydrodibenzo[b,e]thiepin and its 2-bromo derivative with the isomeric (dimethylaminomethyl)phenols, (dimethylaminomethyl)thiophenols, and (dimethylaminomethyl)anilines in toluene afforded the title compounds IIIb,c, Va, VIIIa,b,c, and Xa,b,c. Reactions of 11-chloro-6,11-dihydrodibenzo[b,e]thiepin and its 2-chloro and 2-methyl derivatives with N,N-dimethyl-2-(4-aminophenoxy)ethylamine and N,N-dimethyl-3-(4-aminophenoxy)propylamine by heating in dimethylformamide in the presence of sodium carbonate gave the diamino ethers XI-XIV. The compounds showed only indication

APA, Harvard, Vancouver, ISO, and other styles

21

Wang, Yinan, Hui Chen, Ruilong Sheng, et al. "Synthesis and Bioactivities of Marine Pyran-Isoindolone Derivatives as Potential Antithrombotic Agents." Marine Drugs 19, no. 4 (2021): 218. http://dx.doi.org/10.3390/md19040218.

Full text

Abstract:

2,5-Bis-[8-(4,8-dimethyl-nona-3,7-dienyl)-5,7-dihydroxy-8-methyl-3-keto-1,2,7,8-teraahydro-6H-pyran[a]isoindol-2-yl]-pentanoic acid (FGFC1) is a marine pyran-isoindolone derivative isolated from a rare marine microorganism Stachybotrys longispora FG216, which showed moderate antithrombotic(fibrinolytic) activity. To further enhance its antithrombotic effect, a series of new FGFC1 derivatives (F1–F7) were synthesized via chemical modification at C-2 and C-2′ phenol groups moieties and C-1″ carboxyl group. Their fibrinolytic activities in vitro were evaluated. Among the derivatives, F1–F4 and F6

APA, Harvard, Vancouver, ISO, and other styles

22

Dabaeva, V. V., M. R. Baghdasaryan, I. M. Barkhudaryants, E. G. Paronikyan, and Sh Sh Dashyan. "Synthesis of new fused 3(4)-substituted 11-furylthieno[3,2-<i>d</i>]pyrimidine derivatives." Журнал общей химии 93, no. 9 (2023): 1351–57. http://dx.doi.org/10.31857/s0044460x23090056.

Full text

Abstract:

A method was developed for the synthesis of new fused 3-alkyl-substituted derivatives of thieno[3,2- d ]pyrimidin-4(3 H )-ones based on 11-(2-furyl)-8,8-dimethyl-7,10-dihydro-8 H -pyrano[3′′,4′′:5′,6′]pyrido[3′,2′:4,5]-thieno[3,2- d ]pyrimidin-4(3 H )-one via nucleophilic substitution in the pyrimidine ring. A series of fused 4-amino-substituted 11-furylthieno[3,2- d ]pyrimidine derivatives was also synthesized from the corresponding 4-chloro derivative.

APA, Harvard, Vancouver, ISO, and other styles

23

Fischer, Alfred, George N. Henderson, and Lokanathan M. Iyer. "ipso Nitration. XXVI. Nitration of 1,2-dimethyl-4-nitrobenzene. Formation and reactions of adducts." Canadian Journal of Chemistry 63, no. 9 (1985): 2390–400. http://dx.doi.org/10.1139/v85-396.

Full text

Abstract:

Nitration of 1,2-dimethyl-4-nitrobenzene in a mixture of acetic anhydride and trifluoroacetic anhydride gives the diastereoisomers of 4,5-dimethyl-2,4-dinitrocyclohexa-2,5-dienyl acetate (50%), in addition to the 1,2-dimethyldinitrobenzenes. In moderate and more strongly acid conditions the adduct gives 4-nitro-, 3,4-dinitro-, and 3,5-dinitro-o-xylene. In neutral and weakly acid solutions 4-nitro- and 3,5-dinitro-o-xylene are formed by a radical and a sigmatropic pathway. The adduct reacts facilely with nucleophiles by allylic substitution to give a 5,6-dimethyl-6-nitrocyclohexa-2,4-dienyl der

APA, Harvard, Vancouver, ISO, and other styles

24

Hartwig de Oliveira, Daniela, Fernanda Severo Sabedra Sousa, Paloma Taborda Birmann, et al. "Evaluation of antioxidant activity and toxicity of sulfur- or selenium-containing 4-(arylchalcogenyl)-1H-pyrazoles." Canadian Journal of Physiology and Pharmacology 98, no. 7 (2020): 441–48. http://dx.doi.org/10.1139/cjpp-2019-0356.

Full text

Abstract:

Pyrazoles represent a significant class of heterocyclic compounds that exhibit pharmacological properties. The present study aimed to investigate the antioxidant potential of pyrazol derivative compounds in brain of mice in vitro and the effect of pyrazol derivative compounds in the oxidative damage and toxicity parameters in mouse brain and plasma of mice. The compounds tested were 3,5-dimethyl-1-phenyl-4-(phenylselanyl)-1H-pyrazol (1a), 3,5-dimethyl-4-(phenylselanyl)-1H-pyrazole (2a), 4-((4-methoxyphenyl)selanyl)-3,5-dimethyl-1-phenyl-1H-pyrazole (3a), 4-((4-chlorophenyl)selanyl)-3,5-dimethy

APA, Harvard, Vancouver, ISO, and other styles

25

Spassova, Maria K., Antonín Holý, and Milena Masojídková. "Ribonucleosides of 3-amino- and 3,5-diaminopyrazole-4-carboxylic acid and their open-chain analogues: Synthesis and reactions." Collection of Czechoslovak Chemical Communications 51, no. 7 (1986): 1512–31. http://dx.doi.org/10.1135/cccc19861512.

Full text

Abstract:

Bis(trimethylsilyl) derivative of ethyl 3-aminopyrazole-4-carboxylate (VI) and tris(trimethylsilyl) derivative of ethyl 3,5-diaminopyrazole-4-carboxylate (VII) on reaction with 2,3,5-tri-O-benzoyl-D-ribofuranolyl chloride and subsequent debenzoylation afforded the respective β-D-ribofuranosyl derivatives VIIIa and Xa. Their alkaline hydrolysis led to 1-(β-D-ribofuranosyl)-3-aminopyrazole-4-carboxylic acid (VIIIc) and 1-(β-D-ribofuranosyl)-3,5-diaminopyrazole-4-carboxylic acid (Xb). The esters VIIIa and Xa were not ammonolyzed under normal conditions. Contrary to nucleosidation of the silyl der

APA, Harvard, Vancouver, ISO, and other styles

26

Kurfürst, Antonín, and Pavel Šebek. "On reactivity of 2,6-dichloro-3,5-diformyl-1,4,4-trimethyl-1,4-dihydropyridine." Collection of Czechoslovak Chemical Communications 54, no. 6 (1989): 1705–15. http://dx.doi.org/10.1135/cccc19891705.

Full text

Abstract:

2,6-Dichloro-3,5-diformyl-4,4-dimethyl-1,4-dihydropyridines IIb-IId have been prepared by the Vilsmeier-Haack reaction of glutarimides I, and possible chemical transformations of the trimethyl derivative IIc have been examined. The bis-oxime IVa and bis-(2,4-dinitrophenylhydrazone) Vb are formed by the respective reactions of the formyl groups. The nucleophilic substitutions of chlorine give the corresponding derivatives IX-XII. The cyclocondensation reaction of compound IIc with the respective reagents gives the condensed heterocyclic derivatives VI, XIII, and XIV. The physico-chemical charac

APA, Harvard, Vancouver, ISO, and other styles

27

El-Alali, Abdullah, and Ahmed S. Al-Kamali. "Reactions of 1,3-dipolar aldazines and ketazines with the dipolarophile dimethyl acetylenedicarboxylate." Canadian Journal of Chemistry 80, no. 10 (2002): 1293–301. http://dx.doi.org/10.1139/v02-169.

Full text

Abstract:

The prepared aldazines (aldehyde azines) and ketazines (ketone azines) were allowed to react with 2 mol of the acetylene derivative. The first products formed were pentalene azine derivatives, which in some cases underwent skeletal rearrangment into acyclic tetraene azines. The latter underwent, in the case of some aldazine products, further skeletal rearrangment into N-allyl pyrazoles. The occurence of these rearrangments is dependant on the nature of the aldehydes or ketones used.Key words: dimethyl acetylenedicarboxylate (DMAD), aldazines, ketazines, N-allyl pyrazoles.

APA, Harvard, Vancouver, ISO, and other styles

28

Al-Sheikh, Ahmad, Kamal Sweidan, Cäcilia Maichle-Mößmer, Manfred Steimann, and Norbert Kuhn. "Synthesis and Reactions of 5-[Amino(thiomethyl)methylene]- 2,2-dimethyl-1,3-dioxane-4,6-dione." Zeitschrift für Naturforschung B 64, no. 1 (2009): 101–5. http://dx.doi.org/10.1515/znb-2009-0113.

Full text

Abstract:

5-[Amino(thiomethyl)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione (4) is obtained from 5-[bis- (thiomethyl)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione (1) and aqueous ammonia in excellent yield. Its reaction with m-chloroperbenzoic acid gives the sulfoxide derivative 5-[amino(sulfinylmethyl) methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione (5). With triphenylphosphine, 5 reacts to give triphenyl( thiomethyl)phosphonium 5-cyano-2,2-dimethyl-1,3-dioxane-4,6-dionate (6) from which the methyltriphenylphosphonium salt 6a is obtained with excess triphenylphosphine. The crystal structures of 4, 5 and

APA, Harvard, Vancouver, ISO, and other styles

29

Vidal, Isabel, Elena Fernández-Florido, Ana Dácil Marrero, et al. "The Immunomodulator Dimethyl Itaconate Inhibits Several Key Steps of Angiogenesis in Cultured Endothelial Cells." International Journal of Molecular Sciences 23, no. 24 (2022): 15972. http://dx.doi.org/10.3390/ijms232415972.

Full text

Abstract:

The dimethyl derivative of the immunomodulator itaconate has been previously shown to have anti-inflammatory, anti-oxidative, and immunomodulatory effects. In the present work, we evaluate the potential of dimethyl itaconate as an anti-angiogenic compound by using cultured endothelial cells and several in vitro assays that simulate key steps of the angiogenic process, including endothelial cell proliferation, migration, invasion, and tube formation. Our results show that dimethyl itaconate interferes with all the previously mentioned steps of the angiogenic process, suggesting that dimethyl it

APA, Harvard, Vancouver, ISO, and other styles

30

Mitchell, Reginald H., Xin Jin, Tetsuo Otsubo, and Kazuo Takimiya. "An annulene TCNQ derivative with rather weak acceptor properties." Canadian Journal of Chemistry 75, no. 6 (1997): 611–15. http://dx.doi.org/10.1139/v97-072.

Full text

Abstract:

Reaction of the bridged [14]annulenequinone, trans-10b,10c-dimethyl-10b,10c-dihydropyrene-2,7-quinone (12), with malononitrile in the presence of pyridine and TiCl4 gave 68% of the deep-purple extended TCNQ derivative, α,α,α′,α′-tetracyano-trans-10b, 10c-dimethyl-10b, 10c-dihydropyrene-2,7-quinodimethide (13). In solution, quinodimethide 13 appears to form a complex with diethylamine, but is too weak an electron acceptor to form complexes with tetrathiafulvalene, TTF, and related donors. The reduction potential of 13 was substantially lower than that found for TCNQ itself, and in properties 13

APA, Harvard, Vancouver, ISO, and other styles

31

Guan, Jinming, Matthew Hachey, Lekha Puri, Vanessa Howieson, Kevin J. Saliba, and Karine Auclair. "A cross-metathesis approach to novel pantothenamide derivatives." Beilstein Journal of Organic Chemistry 12 (May 13, 2016): 963–68. http://dx.doi.org/10.3762/bjoc.12.95.

Full text

Abstract:

Pantothenamides are known for their in vitro antimicrobial activity. Our group has previously reported a new stereoselective route to access derivatives modified at the geminal dimethyl moiety. This route however fails in the addition of large substituents. Here we report a new synthetic route that exploits the known allyl derivative, allowing for the installation of larger groups via cross-metathesis. The method was applied in the synthesis of a new pantothenamide with improved stability in human blood.

APA, Harvard, Vancouver, ISO, and other styles

32

Díaz, E., H. Barrios, A. Gúzman та ін. "2D1H and13C NMR studies of the adducts obtained by cyclostereoselective oligomerization ofα,β‒unsaturated arylidenketones promoted by 6 amino‒1,3‒dimethyl uracil". Spectroscopy 14, № 4 (2000): 177–94. http://dx.doi.org/10.1155/2000/162973.

Full text

Abstract:

The reaction of the 6‒amino‒1,3‒dimethyl uracil with the arylidenketones1–4, enabled us to obtain adducts whose structures result from nucleophilic attack and self condensation, yielding with monomeric, dimeric or trimeric derivatives obtained with moderate (40–50%) yields. The reaction was induced by the uracil derivative and the role of this reagent was that of a nucleophile and oligomerization promoter. The structures obtained in this study were mainly elucidated with 1D and 2D high resolution NMR experiments.

APA, Harvard, Vancouver, ISO, and other styles

33

Schaefer, Ted, Rudy Sebastian, Glenn H. Penner, and S. R. Salman. "The proximate spin–spin coupling, 5J(F,CH3), as a quantitative conformational indicator in alkylfluorobenzenes and related compounds." Canadian Journal of Chemistry 64, no. 8 (1986): 1602–6. http://dx.doi.org/10.1139/v86-266.

Full text

Abstract:

The through-space or proximate nuclear spin–spin coupling constant, 5J(F,CH3) = 5J, between methyl protons and ring fluorine nuclei in alkylfluorobenzenes is postulated as [Formula: see text] θ being the torsional angle for the [Formula: see text] bond. A and B are obtained from the known internal rotational behaviour in 2,6-difluoroethylbenzene and the corresponding cumene derivative. The parameterization is tested on the observed 5J in derivatives of 2,4,6-tri-tert-butyl- and 2,4,6-tri-isopropyl-fluorobenzene, in 2-chloro-6-fluoroisopropylbenzene, 2,6-difluoro-α-methylstyrene, and N-methyl-8

APA, Harvard, Vancouver, ISO, and other styles

34

Jones, R., S. J. Rettig, J. R. Scheffer, J. Trotter, and J. Yang. "Structures and photochemistry of 1,5-disubstituted dibenzobarrelenes." Acta Crystallographica Section B Structural Science 52, no. 1 (1996): 151–58. http://dx.doi.org/10.1107/s0108768195005854.

Full text

Abstract:

The effect of 1,5-disubstitution on the photochemistry of 9,10-ethenoanthracene-11,12-diesters has been studied and correlated with the crystal structures determined for several derivatives; photoproduct structures have been established from a crystal structure analysis of one of the products and from NMR correlations. The crystals studied are: (1)-Cl, dimethyl 1,5-dichloro-9,10-dihydro-9,10-ethenoanthracene-11,12-dicarboxylate, C20H14Cl2O4, P21/n; (1)-CN, 1,5-dicyano derivative, C22H14N2O4, P21/n; (1)-CN.0.5p-xylene, C22H14N2O4.0.5C8H10, P21/c; (1)-CN.xxylene, C22H14N2O4.xC8H10, P21/n; (1)-OM

APA, Harvard, Vancouver, ISO, and other styles

35

Alonso-Galicia, Magdalena, John R. Falck, Komandla Malla Reddy, and Richard J. Roman. "20-HETE agonists and antagonists in the renal circulation." American Journal of Physiology-Renal Physiology 277, no. 5 (1999): F790—F796. http://dx.doi.org/10.1152/ajprenal.1999.277.5.f790.

Full text

Abstract:

The present study examined the effects of a series of 20-hydroxyeicosatetraenoic acid (20-HETE) derivatives on the diameter of renal arterioles to determine the structural requirements of the vasoconstrictor response to 20-HETE. The vascular responses to 5-, 8-, 12-, 15-, 19-, 20-, 21-HETEs, arachidonic acid (AA), and saturated, partially saturated, dimethyl, carboxyl, and 19-carbon derivatives of 20-HETE (10−8 to 10−6 M) were assessed in rat renal interlobular arteries (65–125 μm). 20-HETE, 21-HETE, dimethyl-20-HETE, and a partially saturated derivative of 20-HETE, 20-hydroxyeicosa-5( Z),14(

APA, Harvard, Vancouver, ISO, and other styles

36

Riegert, Ulrich, Gesche Heiss, Peter Fischer, and Andreas Stolz. "Distal Cleavage of 3-Chlorocatechol by an Extradiol Dioxygenase to 3-Chloro-2-Hydroxymuconic Semialdehyde." Journal of Bacteriology 180, no. 11 (1998): 2849–53. http://dx.doi.org/10.1128/jb.180.11.2849-2853.1998.

Full text

Abstract:

ABSTRACT A 2,3-dihydroxybiphenyl 1,2-dioxygenase from the naphthalenesulfonate-degrading bacterium Sphingomonas sp. strain BN6 oxidized 3-chlorocatechol to a yellow product with a strongly pH-dependent absorption maximum at 378 nm. A titration curve suggested (de)protonation of an ionizable group with a pKaof 4.4. The product was isolated, purified, and converted, by treatment with diazomethane, to a dimethyl derivative and, by incubation with ammonium chloride, to a picolinic acid derivative. Mass spectra and 1H and 13C nuclear magnetic resonance (NMR) data for these two derivatives prove a 3

APA, Harvard, Vancouver, ISO, and other styles

37

Collins, David J., Timothy C. Hughes, and Wynona M. Johnson. "Dihydro-1,2,4-triazin-6(1H)-ones. II Synthesis of Several Methylated 3-Phenyl- 4,5-dihydro-1,2,4-triazin-6(1H)-ones." Australian Journal of Chemistry 52, no. 5 (1999): 379. http://dx.doi.org/10.1071/ch99012.

Full text

Abstract:

Novel syntheses of 4,5-dihydro-1,2,4-triazin-6(1H)-ones were developed by use of imidoyl chlorides. The overall yield of 4,5-dihydro-1,2,4-triazin-6(1H)-ones prepared from amino acid imidates and hydrazines was improved by the development of a much more efficient synthesis of the imidates. The new 1,2-, 1,4- and 5,5-dimethyl dihydro-1,2,4-triazin-6(1H)-ones have been synthesized by cyclocondensation/cycloaddition pathways. Base-catalysed methylation of 3-phenyl-4,5-dihydro-1,2,4-triazin-6(1H)-one (15) gave the 1- methylated derivative (8); under similar conditions 2-methyl-3-phenyl-2,5-dihydro

APA, Harvard, Vancouver, ISO, and other styles

38

Sahb, Mohaned M., and Zeina M. Kadam. "Synthesis and Biological Activity of New Derivatives of Thiazolidine and Oxazepine-Linked to Pyridine Moieties." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 12, no. 03 (2022): 947–51. http://dx.doi.org/10.25258/ijddt.12.3.03.

Full text

Abstract:

This research includes reaction and condensation between substituted 4-aminopyridine and 4-(N, N-dimethyl amino benzaldehyde) to produce Schiff base derivative (3), the compound (3) was selected to react with a different compound such as Thioglycolic acid, Phthalic anhydride, and maleic anhydride, to produced new ring of Thiazolidine derivatives and oxazepine derivatives structures (4,5,6,7,8,9,10,11,12), respectively. The final compound was characterized the structure by Fourier transform-infrared spectroscopy, H-Nuclear magnetic resonance (H-NMR) in addition to the Carbon, Hydrogen, Nitrogen

APA, Harvard, Vancouver, ISO, and other styles

39

Xia, Danyu, Pi Wang, and Bingbing Shi. "Controlling the photochemical reaction of an azastilbene derivative in water using a water-soluble pillar[6]arene." Organic & Biomolecular Chemistry 15, no. 36 (2017): 7618–22. http://dx.doi.org/10.1039/c7ob01441d.

Full text

Abstract:

A host–guest system in water based on a water-soluble pillar[6]arene and an azastilbene derivative, (E)-4,4′-dimethyl-4,4′-diazoniastilbene diiodide, has been constructed. Then this water-soluble pillar[6]arene was successfully used to control the photohydration of the azastilbene derivative in water as a “protective agent”.

APA, Harvard, Vancouver, ISO, and other styles

40

Tong, Fei, Daichi Kitagawa, Xinning Dong, Seiya Kobatake, and Christopher J. Bardeen. "Photomechanical motion of diarylethene molecular crystal nanowires." Nanoscale 10, no. 7 (2018): 3393–98. http://dx.doi.org/10.1039/c7nr09571f.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Unde, Pradip J., Kiran D. Dhawale, Satish G. Parte, and Limbraj R. Patil. "Microwave Assisted Synthesis of Some Novel Pyrimidine Derivative and Screening for their Biological Activity." Asian Journal of Organic & Medicinal Chemistry 5, no. 4 (2020): 289–94. http://dx.doi.org/10.14233/ajomc.2020.ajomc-p292.

Full text

Abstract:

A substituted pyrimidine derivatives were synthesized from chalcone of 3-acetyl-2,5-dimethyl thiophene with corresponding active aldehyde in microwave oven. The newly synthesized compounds were characterized by TLC, IR, 1H NMR, 13C NMR spectral analysis. Pyrimidine derivative were screened for their antibacterial activity in vitro by the disk diffusion assay against two Gram-positive and two Gram-negative bacteria and then the minimum inhibitory concentration (MIC) was carried with the reference of standard drugs amoxicillin, ampicillin and ciprofloxacin. The pyrimidine derivatives shows bette

APA, Harvard, Vancouver, ISO, and other styles

42

Man, Wong Wee Choy Wong Chi, Hans Pritzkow, and Walter Siebert. "Notizen: Synthesis and Structure of a 2,4,5-Tris(methylene)-1-bora-3-silacyclopentane Derivative." Zeitschrift für Naturforschung B 46, no. 8 (1991): 1127–29. http://dx.doi.org/10.1515/znb-1991-0827.

Full text

Abstract:

3,3-Dimethyl-(e)-1-chlorodimethylsilyl-1-chloro-dimethylaminoboryl-butene-1 (5) reacts with 3,4-dilithio-2,5-dimethyl-2,4-hexadiene in diethylether to give colorless 2-(tert-butylmethy-lene)-4,5-bis(dimethylmethylene)-1-dimethylamino-3-dimethyl-1-bora-3-sila-cyclopentane (4) in 41% yield. The X-ray structure analysis shows a non-planar ring with a small angle C2-Si3-C4 = 94.9(1)°.

APA, Harvard, Vancouver, ISO, and other styles

43

Breker, Johannes, Ulrich Wermuth та Reinhard Schmutzler. "Verbindungen mit dem 1,3-Dimethyl-1,3-diaza-2-phosphetidin-4-on-Grundgerüst; Synthese von 1,3-Dimethyl-2-thia-1,3-diaza-2 λ4-phosphetidin-4-on-Derivaten / Compounds Involving the 1,3-Dimethyl-1,3-diaza-2-phosphetidine-4-one Structure; Synthesis of 1,3-Dimethyl-2-thia-1,3-diaza-2λ4-phosphetidine-4-one Derivatives". Zeitschrift für Naturforschung B 45, № 10 (1990): 1398–406. http://dx.doi.org/10.1515/znb-1990-1009.

Full text

Abstract:

In the reaction with hexamethyldisilthiane the cyclic trichlorophosphorane O=C(NMe)2PCl3 (1) was converted to the new compound O=C(NMe)2P(=S)Cl (2). A range of derivatives, O=C(NMe)2P(=S)Y (Y=NR2, OMe, SMe, 3-7) was obtained in the reaction of 2 with the appropriate trimethylsilyl derivatives, Me3SiY. The compounds 8 and 9 (Y=NPh2 and N(C6H11)2) could not be synthesized by this route as the required trimethylsilyl derivative was not reactive enough (Me3SiNPh2) or was not available (Me3SiN(C6H11)2), presumably on account of the bulk of the NPh2 and N(C6H11)2 groups. 8 and 9 could be prepared by

APA, Harvard, Vancouver, ISO, and other styles

44

Kuhn, Norbert, Ahmad Al-Sheikh, Simon Schwarz, and Manfred Steimann. "Zwitterionische Imidazolium- und Phosphonium-Derivate der Methylenmeldrumsäure [1,2] / Zwitterionic Imidazolium and Phosphonium Derivatives of Methylene-Meldrum’s Acid [1,2]." Zeitschrift für Naturforschung B 60, no. 4 (2005): 398–402. http://dx.doi.org/10.1515/znb-2005-0407.

Full text

Abstract:

2,2-Dimethyl-4,6-dioxo-5-pyridinomethyl-1,3-dioxan-5-yl-pyridinium ylide (9) reacts with 2,3-dihydro- 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene (1; R1 = iPr, R2 = Me) to give the zwitterionic imidazolium derivative 2,2-dimethyl-4,6-dioxo-5-(1,3-diisopropyl-4,5-dimethylimidazoliomethyl)- 1,3-dioxan-5-yl-imidazolium ylide (4) in good yield. Similarly, the phosphonium compound 2,2-dimethyl-4,6-dioxo-5-triphenylphosphoniomethyl-1,3-dioxan-5-yl-phosphonium ylide (5) is obtained from 9 and PPh3. The crystal structures of 4 and 5 are reported

APA, Harvard, Vancouver, ISO, and other styles

45

Li, Zhanfeng, Xiangkun Wang, Xiang Lv, et al. "An ambipolar 3,3′-dimethyl-9,9′-bianthracene derivative as a blue host material for high-performance OLEDs." RSC Adv. 7, no. 77 (2017): 49125–32. http://dx.doi.org/10.1039/c7ra09179f.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Al-Sheikh, Ahmad, Kamal Sweidan, Norbert Kuhn, Cäcilia Maichle-Mößmer, and Manfred Steimann. "Elimination of a Thiomethyl Substituent from an Anionic 5-Methylenebarbituric Acid Derivative by Oxidation and Substitution." Zeitschrift für Naturforschung B 64, no. 3 (2009): 307–12. http://dx.doi.org/10.1515/znb-2009-0309.

Full text

Abstract:

Triethylammonium 5-[(1,3-dimethyl-2,4,6-trioxo-tetrahydropyrimidin-5(6H)-ylidene)-(methylthio) methyl]-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-olate (5), obtained from 5-[bis (methylthio)methylene]-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione (2) and 1,3-dimethylbarbituric acid in the presence of triethylamine, is protonated by methanesulfonic acid to give 5,5ʹ-(methylthiomethanediylidene)bis(1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione) (6) in good yield. Compound 6 is oxidized in two steps by m-chloroperbenzoic acid to give 5,5ʹ- (methylsulfinylmethanediylidene)bis(1,3-dimethy

APA, Harvard, Vancouver, ISO, and other styles

47

Thomas, Mallory E., Lynn D. Schmitt, and Alistair J. Lees. "An Investigation into Anion Sensing of the Molecular Aggregate of 4-(Pyrrol-1-yl)pyridine and Its Derivatives." Molecules 29, no. 23 (2024): 5692. https://doi.org/10.3390/molecules29235692.

Full text

Abstract:

Recently, 4-(pyrrol-1-yl)pyridine has been found to act as a supramolecular chemodosimeter, sensing nitrite ions in an aqueous solution with naked eye detection and a low limit of detection of 0.330 ppm. This work explores the anion-sensing properties of related derivatives, 4-(2,5-dimethyl-pyrrol-1-yl)pyridine and 4-(2,4-dimethyl-pyrrol-1-yl)pyridine, and provides a comparison with the parent compound. These molecules are determined to be effective sensors for nitrite ions with limits of detection of 1.06 ppm and 1.05 ppm, respectively. The high sensitivity and selectivity to nitrite remain e

APA, Harvard, Vancouver, ISO, and other styles

48

Kuhn, Norbert, Alois Kuhn, Elke Niquet, Manfred Steimann, and Kamal Sweidan. "Derivate der 1,3-Dimethyl-5-methylen-barbitursüure / Derivatives of 1,3-Dimethyl-5-methylenebarbituric Acid." Zeitschrift für Naturforschung B 60, no. 9 (2005): 924–28. http://dx.doi.org/10.1515/znb-2005-0902.

Full text

Abstract:

1,3-Dimethylbarbituric acid (1, R = Me) reacts with aqueous formaldehyde in the presence of pyridine to give 1,3-dimethyl-2,4,6-trioxo-5-pyridinomethyl-1,3-perhydrodiazin-5-ylpyridinium ylide (6) in good yield. From 6 and 2,3-dihydro-1,3-diisopropyl-4,5-dimethylimidazol- 2-ylidene (7), the zwitterionic imidazolium derivative 1,3-dimethyl-2,4,6-trioxo-5-(1,3-diisopropyl- 4,5-dimethylimidazoliomethyl)-1,3-perhydrodiazin-5-yl-imidazolium ylide (8) is obtained. Similarly, the phosphonium compound 1,3-dimethyl-2,4,6-trioxo-5-triphenylphosphoniomethyl-1,3- perhydrodiazin-5-y l-phosphonium ylide (9)

APA, Harvard, Vancouver, ISO, and other styles

49

Hajib, Alami, Faraj, and Aouine. "4-[(3,5-Dimethyl-1H-pyrazol-1-yl)methyl]-4-methyl-2-phenyl-4,5-dihydrooxazole." Molbank 2019, no. 3 (2019): M1074. http://dx.doi.org/10.3390/m1074.

Full text

Abstract:

The compound, 4-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]-4-methyl-2-phenyl-4,5-dihydrooxazole 2 was prepared in high yield, through nucleophilic substitution reaction of the O-tosyl oxazoline derivative 1, by heating in dimethyl sulfoxide (DMSO) and in presence of KOH as base. The structure of the synthesized compound was established on the basis of NMR spectroscopy (1H, 13C), MS data and elemental analysis.

APA, Harvard, Vancouver, ISO, and other styles

50

Bonilla-Castañeda, Sandra M., Andrés F. Villamizar-Mogotocoro, and Vladimir V. Kouznetsov. "[4-(3,4-Dimethoxyphenyl)-3,6-dimethyl-2-phenyl-3,4-dihydroquinolin-1(2H)-yl)](furan-2-yl)methanone." Molbank 2022, no. 3 (2022): M1413. http://dx.doi.org/10.3390/m1413.

Full text

Abstract:

A N-(2,4-diaryltetrahydroquinolin-1-yl) furan-2-carboxamide derivative, [4-(3,4-dimethoxyphenyl)-3,6-dimethyl-2-phenyl-3,4-dihydroquinolin-1(2H)-yl)](furan-2-yl)methanone, was synthesized in a two-step procedure from p-toluidine, benzaldehyde, and trans-methyl-isoeugenol as commercial starting reagents through a sequence of Povarov cycloaddition reaction/N-furoylation processes. The structure of the compound was fully characterized by IR, 1H, 13C-NMR, and X-ray diffraction data. Such types of derivatives are known as relevant therapeutic agents exhibiting potent anticancer, antibacterial, anti

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!