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Quon, Harvey, Derek Suderman, Kimi Guilbert, and Pascal Lambert. "Patterns of referral for adjuvant radiotherapy after radical prostatectomy in men with prostate cancer: A population-based analysis." Journal of Clinical Oncology 30, no. 5_suppl (February 10, 2012): 140. http://dx.doi.org/10.1200/jco.2012.30.5_suppl.140.
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140 Background: Randomized trials have shown improved biochemical disease free survival after adjuvant radiotherapy (ART) in patients with pT3 or margin positive disease after radical prostatectomy for prostate cancer. This study examines the rates of referral to a radiation oncologist for patients with high risk pathologic features after prostatectomy. Also, the impact of the presentation of these randomized trials will be examined. Methods: All men diagnosed in the province of Manitoba with prostate adenocarcinoma between 2003 and 2008 who underwent radical prostatectomy were identified through a central cancer registry database. Manual chart review was performed and detailed demographic and clinico-pathologic data were analyzed to determine their influence on referral to a radiation oncologist within 6 months of surgery. Analysis of referral rates before and after the presentation of 2 randomized trials were also examined. Results: A total of 1080 patient records of men undergoing prostatectomy for prostate cancer were reviewed. Of these, 546 (50.6%) men had at least one high risk pathologic feature. This includes pT2 margin positive disease in 298/546 (54.6%), pT3a in 154/546 (28.2%), and pT3b in 94/546 (17.2%). Multivariable logistic regression was performed adjusting for age, distance from cancer centre, Gleason score, T stage, perineural invasion, and margin status. Gleason score 8-10 (p<0.0001), higher pathologic T stage (p<0.0001), and farther distance (p=0.0028) were associated with referral for ART. Age and margin status were not significantly associated. Men with pT3a (odds ratio 3.35) and pT3b disease (odds ratio 5.32) were more likely to be referred than pT2 margin positive disease (p<0.0001). There were 78/546 (14.3%) patients with a high risk factor who were referred for ART within 6 months of surgery. The rates of referral were not significantly different before and after the presentation of randomized trials (p=0.60). Conclusions: Men with higher pathologic stage (pT3) and grade (Gleason 8-10) are more likely to receive ART. However, referral for ART did not increase significantly after presentation of the randomized trials and remains underutilized.
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Admin, Admin, Romi Djafar, and Agus Susanto Ginting. "RANCANG BANGUN DAN UJI KINERJA MESIN PEMARUT DAN PEMERAS SANTAN KELAPA." Jurnal Teknologi Pertanian Gorontalo (JTPG) 4, no. 1 (June 24, 2019): 41–45. http://dx.doi.org/10.30869/jtpg.v4i1.344.
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Porivinsi Gorontalo merupakan salah satu sentra penghasil kelapa berdasarakan data BPS tahun 2016, gorontalo menghasilkan 54,6 ribu ton kelapa. Secara umum proses ekstraksi daging kelapa menjadi santan dilakukan dengan proses pemerasan secara manual. Selain dilakukan secara manual proses ektraksi juga dapat dilakukan dengan menggunakan mesin. Beberapa industri rumah tangga sudah menggunakan mesin pemeras santan dengan sistem batch dengan kapasitas yang relatif kecil. Proses pemerasan merupakan proses yang terpisah dengan pemarutan sehingga membutuhkan waktu yang lebih lama dalam ektraksi daging kelapa menjadi santan. Pada penelitian ini akan difokuskan bagaimana cara untuk memaraut kelapa yang selanjutnya diperas untuk menghasilkan santan kelapa secara berkenlajutan (Continu)
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UYANIK, Ayşe. "Beitrag Der Überzetzung Zu Den Rezeptiven Srachfertigkeiten." Journal of Turkish Studies 8, Volume 8 Issue 8 (January 1, 2013): 1363. http://dx.doi.org/10.7827/turkishstudies.5416.
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Ariswandy, Hazairin Habe, David. "KONTRIBUSI GAYA KEPEMIMPINAN DAN DISIPLIN KERJA TERHADAP PENINGKATAN KINERJA PEGAWAI PADA KANTOR BIRO KESEJAHTERAAN RAKYAT PEMERINTAH PROVINSI LAMPUNG." JURNAL ILMU MANAJEMEN SABURAI (JIMS) 6, no. 2 (December 14, 2020): 85–92. http://dx.doi.org/10.24967/jmb.v6i2.1099.
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Abstrak. Penelitian ini bertujuan untuk mengetahui bagaimana kontribusi gaya kepemimpinan dan disiplin kerja terhadap peningkatan kerja pegawai pada kantor Biro Jasa Kesejahteraan Rakyat Pemerintah Provinsi Lampung. Penelitian yang dilaksanakan jenis penelitian Explanatory yaitu model pemecahan masalah yang menguraikan masalah dan menjelaskannya berdasarkan data data yang ada dalam mengulas secara pendekatan teori dan angka angka yang berhubungan satu dengan lainnya. Penelitian ini menggunakan 52 responden penelitian. Ada tiga variabel dalam penelitian ini yaitu : 2 (dua) Variabel bebas (X1 dan X2) dan 1 (satu) variabel terikat dimana Gaya Kepemimpinan (X1) dan Disiplin Kerja (X2) sebagai variabel bebas dan Peningkatan Kinerja Pegawai (Y) sebagai variabel terikat. Dari hasil pengolahan data telah berhasil ditemukan jawaban hipotesis yakni sebagai berikut Terdapat kontribusi antara gaya kepemimpinan (X1), disiplin kerja (X2) dengan peningkatan kinerja pegawai (Y), dengan tingkat kontribusi sebesar 54,6% yang berarti bahwa gaya kepemimpinan dan disiplin kerja memberikan kontribusi sebesar 54,6% terhadap peningkatan kinerja pegawai. Kata kunci : Gaya Kepemimpinan, Disiplin Kerja, Peningkatan Kinerja Pegawai.
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Goets, Stefan A., Tineke Kraaij, and Keith M. Little. "Seed bank and growth comparisons of native (Virgilia divaricata) and invasive alien (Acacia mearnsii and A. melanoxylon) plants: implications for conservation." PeerJ 6 (August 21, 2018): e5466. http://dx.doi.org/10.7717/peerj.5466.
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Background Invasive alien plants with long-lived dormant seed banks and fast growth rates are difficult to manage. Acacia mearnsii and Acacia melanoxylon are two such invaders in the southern Cape of South Africa which occasionally co-occur with a native, ecologically analogous species, Virgilia divaricata. We compared the performance of these three species to determine potential for the native species to be used in management of the invasives. Methods We compared the study species in terms of (i) soil seed bank densities, their vertical distribution, and the viability of seeds underneath the canopies of mature trees; (ii) seedling growth from planted seeds over a period of three months; and (iii) growth rates of saplings over a period of 10 months in stands that have naturally regenerated in the field (these stands were dominated by A. mearnsii) and where saplings have been exposed to varying levels of competition from surrounding saplings. Results Seed bank densities differed significantly among species but not among soil depth classes. Acacia mearnsii had the highest seed bank densities (mean of 7,596 seeds m−2), followed by V. divaricata (938 seeds m−2) and A. melanoxylon (274 seeds m−2). Seed viability was high (87–91%) in all three study species and did not differ significantly among species or soil depth classes. As seedlings, V. divaricata significantly outgrew A. mearnsii in terms of height, root and shoot dry mass, and root:shoot ratio. Relative growth (the relationship between growth in height and initial height) was negative in the seedlings of both species. Trends during the sapling stage were opposite to those during the seedling stage; A. mearnsii (but not A. melanoxylon) saplings significantly outgrew V. divaricata saplings in height, while relative growth rates were positive in all species. Sapling growth of all species was furthermore uninfluenced by the collective biomass of surrounding competitors. Discussion Our findings suggest that amongst the measures considered, A. mearnsii’s success as an invader is primarily attributable to its large seed banks, and secondly to its vigorous growth in height as saplings. However, the superior growth performance of V. divaricata seedlings and no apparent negative effect of competition from the acacias on sapling growth show promise for its use in integrated management of the acacias.
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gz. "Therapieoptionen gegen den Phantom-Ton." HNO Nachrichten 47, no. 2 (April 2017): 69. http://dx.doi.org/10.1007/s00060-017-5436-4.
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Utomo, Agus Djoko, Mohamad Rasyid Ridho, Edward Saleh, and Dinar Dwi Anugerah Putranto. "PENCEMARAN DI SUNGAI BENGAWAN SOLO ANTARA SOLO DAN SRAGEN, JAWA TENGAH." BAWAL Widya Riset Perikanan Tangkap 3, no. 1 (February 7, 2017): 25. http://dx.doi.org/10.15578/bawal.3.1.2010.25-32.
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Bengawan Solo merupakan sungai yang sudah banyak mengalami perubahan oleh Waduk, Bendungan, Sodetan, dan lain-lain. Bengawan Solo melewati Provinsi Jawa Tengah dan Jawa Timur yang padat penduduk, sekitar 15,2 juta jiwa berdomisili di satuan wilayah Sungai Bengawan Solo dan juga banyak terdapat industri. Permasalahan tersebut dapat berpengaruh langsung terhadap kehidupan organisme air kajian tentang parameter físika-kimia perairan diharapkan dapat memberikan informasi tentang status kualitas perairan di Bengawan Solo. Parameter yang diamati dalam penelitianini adalah oksigen terlarut, karbondioksida, pH, fenol, minyak-lemak, amonia, Cd, Cr, Zn, Pb, Cu, dan CN. Terdapat indikasi bahwa Bengawan Solo di daerah Solo-Sragen dan sekitarnya telah tercemar bobot dengan kualitas air buruk yaitu oksigen rendah (beberapa lokasi kurang dari 2 mg/L, karbon dioksida tinggi (8,8-34,32 mg/L), NH3-N bebas tinggi (beberapa lokasi lebih dari 0,2 mg/L), COD tinggi (1,64-172 mg/L), fenol tinggi (0,087-1,431 mg/L), minyak lemak tinggi (2,6-54,6 mg/L).Konsentrasi logam bobot pada beberapa lokasi yaitu Kampung Sewu, Bak Kramat, dan Tundungan cukup tinggi yaitu Cr= 0,180- 0,375 mg/L, Cu=0,026-0,293 mg/L, dan Zn=0,515-2,892 mg/L. Demikian juga kandungan logam bobot pada ikan sapu-sapu (Liposarcus pardalis) cukup tinggi pada beberapa lokasi Kampung Sewu, Tundungan, Bak Kramat, dan Butuh; Cr=0,856- 2,154 mg/kg, Cu=3, 69-198,48 mg/kg, Pb=1,067 - 2,006 mg/kg, dan Zn=53,516-102,285 mg/kg. Perlu dilakukan pengendalian pencemaran di Bengawan Solo dengan cara meningkatkan kesadaran bersama, pemantauan pembuangan limbah, dan penindakan bagi para pelanggaran. Bengawan Solo River is highly modified by dams, impoundment, reservoir, channelization, etc. It traverse through Central Java and East Java province in its passage from headwaters to the sea. Industries and heavy population (approximately 15.2 million people) near the river have potentially wreaked havoc upon the river. Study on physical and chemical parameters expected provide enough information on water quality condition in Bengawan Solo River. Parameters under study were disolved oxygen, carbondioxid, pH, fenol, NH3-N, oil, and grease, COD, Cr, Cd, Pb, Zn, Cu, and CN. An overview of water quality of Bengawan Solo River in Solo-Sragen region indicates that the segments is already strongly polluted as indicated as low oxygen (some location less than 2 mg/L) and high amount of CO2 (8,8-34.32), high free NH3-N (some location more than 0,2 mg/L), COD (1,64-172 mg/L), fenol (0.087- 1,431 mg/L), and oil and grease (2,6-54.6 mg/L). Heavy metals content of some location at Kampung Sewu, Bak Kramat, and Butuh were Cr=0,180-0,375 mg/L, Cu=0,026-0,293 mg/L, Zn=0,515-2,892 mg/L. Heavy metals content in fish tissue of sapu-sapu were high enough at some location (Kampung Sewu, Tundungan, Bak Kramat, and Butuh); Cr=0,856-2,154 mg/kg, Cu=3,69-198,48 mg/kg, Pb=1,067- 2,006 mg/kg, and Zn=53,516-102,285 mg/kg.
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Lee, Hans C., Hua Wang, Bing-Zong Li, Zhiqiang Wang, Richard Julian Jones, Dongmin Gu, Sean O'Brien, Richard E. Davis, and Robert Z. Orlowski. "CX-5461, a Novel RNA Polymerase I Inhibitor, Is Active Against Wild-Type and Mutant p53 Myeloma Models." Blood 122, no. 21 (November 15, 2013): 4438. http://dx.doi.org/10.1182/blood.v122.21.4438.4438.
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Background Ribosomal RNA (rRNA) forms a major component of ribosomes, which play a critical role in cellular growth and proliferation through regulation of protein synthesis. Increased rRNA transcription and ribosomal biogenesis have been associated with tumorigenesis, and recent reports have suggested that inhibition of rRNA transcription by CX-5461 (Senhwa Biosciences), a novel selective small-molecule inhibitor of RNA polymerase (pol) I, induces cell death in several human tumor types by both p53-dependent and independent mechanisms. These findings led to our hypothesis that selective RNA pol I inhibition with CX-5461 could be a rational new approach to therapy for both wild-type (wt) and mutant p53 multiple myeloma models. Methods Studies with CX-5461 were performed in wt p53 and mutant p53 cell lines, zinc-finger nuclease (ZFN) p53 knock-out (KO) isogenic myeloma cell lines, and bortezomib and carfilzomib-resistant myeloma cell lines. Results Treatment of wt p53 (MM1.S, MOLP8) and mutant p53 (U266, RPMI-8226) myeloma cell lines demonstrated a time and dose dependent decrease in cell proliferation after exposure to CX-5461 with a median inhibitory concentration (IC50) range of 50-100 nM after a 72-hour incubation. A corresponding increase in cleaved PARP, cleaved caspase-9, and cleaved caspase-3 expression was seen on Western blot, as well as increased Annexin V staining on flow cytometry analysis. Notably, the degree of Annexin V staining was less in the p53 mutant cell lines compared to the wt p53 cells at any given drug concentration, but strong apoptotic signaling could be induced in mutant p53 cell lines when using higher concentrations of CX-5461. In addition, co-culturing myeloma cells with GFP+ HS5 stromal cells to mimic the bone marrow microenvironment did decrease the therapeutic effect of CX-5461, but again could be overcome with higher drug concentrations [250-500 nM]. Similar results were seen when isogenic MM1.S ZFN p53 KO cells were used, whose sensitivity to CX-5461 was comparable to that of wt p53 cells. Finally, CX-5461 was also tested on drug-resistant myeloma cell lines that were generated by exposing cells to low concentrations of bortezomib (RMPI-8266, KAS-6/1, ANBL-6) or carfilzomib (KAS-6/1) over time. These drug-resistant cell lines showed sensitivity to CX-5461 with an IC50 in the 100-250 nM concentration range. Gene expression profiling (GEP) of isogenic MM1.S ZFN p53 KO and wt cells revealed that gene expression perturbations by CX-5461 were primarily p53-independent. Additional GEP and pathway analysis in other isogenic ZFN p53 wt and KO cell lines is currently ongoing, with a particular interest in p53-independent mechanisms that may explain the efficacy of CX-5461 in both wt and mutant p53 myeloma models. Conclusion RNA pol I inhibition by CX-5461 is a promising approach to myeloma therapy, with low nanomolar drug activity seen in wt p53, mutant p53, and drug-resistant myeloma cell line models, providing a rationale for translation of CX-5461 into the clinic for the treatment of multiple myeloma. Disclosures: O'Brien: Senhwa Biosciences, Inc: Employment. Orlowski:Bristol-Myers Squibb: Honoraria, Membership on an entity’s Board of Directors or advisory committees, Research Funding; Celgene: Honoraria, Membership on an entity’s Board of Directors or advisory committees, Research Funding; Millennium: The Takeda Oncology Company: Honoraria, Membership on an entity’s Board of Directors or advisory committees, Research Funding; Onyx: Honoraria, Membership on an entity’s Board of Directors or advisory committees, Research Funding; Resverlogix: Research Funding; Array Biopharma: Honoraria, Membership on an entity’s Board of Directors or advisory committees; Genentech: Honoraria, Membership on an entity’s Board of Directors or advisory committees; Merck: Membership on an entity’s Board of Directors or advisory committees.
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Sumanti, Vivi, and Firmansyah Firmansyah. "Pengaruh Lingkungan Kerja Non Fisik Dan Disiplin Kerja Terhadap Kepuasan Kerja Pegawai Pada Kantor Camat Palibelo Kabupaten Bima." Jurnal Manajemen & Bisnis Jayakarta 3, no. 1 (July 25, 2021): 47–65. http://dx.doi.org/10.53825/jmbjayakarta.v3i1.91.
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Penelitian ini bertujuan untuk mengetahui pengaruh lingkungan kerja non fisik dan disiplin kerja terhadap kepuasan kerja pegawai pada Kantor Camat Palibelo Kabupaten Bima. Jenis penelitian yang ditetapkan adalah penelitian penjelasan (explanatory research) dengan pendekatan kuantitatif Sumber data pada penelitian ini adalah data primer. Penelitian ini merupakan penelitian populasi dengan 35 responden pada Kantor Camat Palibelo Kabupaten Bima. Teknik sampling yang digunakan adalah sampling jenuh (total population). Teknik Pengumpulan data penelitian menggunakan metode kuesioner. Metode analisis data menggunakan uji validitas dan reliabilitas, asumsi klasik, regresi linier berganda. Koefisien korelasi, Uji signifikansi menggunakan uji T dan uji F dengan taraf signifikansi 5%. Hasil penelitian menunjukkan bahwa variabel lingkungan kerja non fisik memiliki pengaruh yang signifikan dan menunjukkan hasil positif terhadap kepuasan kerja pgawai. Variabel disiplin kerja berpengaruh positif dan tidak signifikan terhadap kepuasan kerja pegawai. Hasil pengujian dan analisisnya menunjukkan bahwa F hitung > F tabel atau 6,781>3,27 dan nilai signifikasi < 0,05 atau 0,004 < 0,05 maka terdapat pengaruh lingkungan kerja non fisik dan disiplin kerja secara simultan sangat signifikan terhadap kepuasan kerja pegawai. Hal ini dibuktikan dengan nilai koefisien korelasi (R) sebesar 0.546 atau 54,6%, berarti sebesar 54,6 % kontribusi atau pengaruh variabel lingkungan kerja non fisik (X1) dan disiplin kerja (X2) secara simultan (bersama-sama) terhadap variabel Kepuasan kerja (Y), sedangkan sisanya sebesar 45,4 % adalah pengaruh faktor lainnya yang tidak diteliti.
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Haerunnisa, Thia, Rosmawita Saleh, and Arris Maulana. "PENGEMBANGAN WEB PEMBELAJARAN PADA MATA KULIAH GAMBAR TEKNIK II FT UNJ." Jurnal PenSil 10, no. 2 (August 15, 2021): 106–13. http://dx.doi.org/10.21009/jpensil.v10i2.20381.
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Abstrak
Penelitian ini bertujuan untuk mengembangkan media pembelajaran berbasis web pada mata kuliah Gambar Teknik II. Penelitian ini termasuk metode penelitian Research and Development (R&D) dengan model penelitian pengembangan ADDIE yang dilakukan dalam lima tahap, yaitu analisis, perancangan, implementasi dan evaluasi. Penelitian pengembangan ini menggunakan instrumen non tes berupa angket. Angket digunakan untuk validasi produk yang dilakukan oleh ahli desain pembelajaran, ahli materi dan ahli media juga menambah penilaian mahasiswa yang telah mengikuti Gambar Teknik II. Hasil kelayakan produk berupa web pembelajaran dengan hasil validasi yaitu ahli desain pembelajaran memperoleh persentase sebesar 62% dengan kategori layak, ahli media mendapatkan persentase sebesar 88% dengan kategori sangat layak dan ahli materi mendapatkan persentase sebesar 90% dengan kategori sangat layak. Untuk hasil belajar siswa, penilaian yang diperoleh yaitu 80% dengan kategori layak dan dari hasil keefektifan produk diperoleh hasil pretest 54,66 dan hasil posttest 82,73. Dapat disimpulkan bahwa web pembelajaran mata kuliah Gambar Teknik II sudah layak dan layak digunakan.
Kata kunci: Web, Gambar Teknik II, Moodle, ADDIE
Abstract
This study aims to develop learning media web-based on the Engineering Drawing II course. This research includes research methods Research and Development (R&D) with a research model ADDIE development is carried out in five stages, namely analysis, design, development, implementation, and evaluation. This development research using a non-test instrument in the form of a questionnaire. Questionnaires are used for validation products carried out by instructional design experts, material experts and media experts also add to the assessments of students who have taken courses Engineering Drawing II. The product feasibility results are in the form of a learning web with the results of expert validation, namely instructional design experts obtained a percentage of 62% with the "feasible" category, media experts get a percentage of 88% with category "very feasible" and material experts get a percentage of 90% with category "very decent". For the results of the student, assessment obtained an average percentage score of 80% with the "feasible" category and from the results of the effectiveness of the product obtained 54.66 pretest results and 82.73 posttest results. It can be concluded that the learning web for the Engineering Drawing II course is appropriate and feasible used.
Keywords: Web, Engineering Drawing II, Moodle, ADDIE
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rb. "Verzicht aufs Frühstück verdirbt den ganzen Tag." CME 12, no. 11 (November 2015): 4. http://dx.doi.org/10.1007/s11298-015-5460-x.
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Fath, Roland. "Frühzeitig & intensiv ran an den Zucker!" CME 12, no. 11 (November 2015): 14. http://dx.doi.org/10.1007/s11298-015-5464-6.
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Fincke, Jeanette C. "Zu den Akkadischen Hemerologien aus Ḫattuša (CTH 546), Teil II: Die "Opferbrot-Hemerologie“." Journal of Cuneiform Studies 62, no. 1 (January 2010): 127–45. http://dx.doi.org/10.1086/jcs41103876.
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Nurrahmaton, Nurrahmaton. "HUBUNGAN GAYA HIDUP DENGAN KEJADIAN MENARCHE DINI PADA REMAJA PUTRI DI SMP AMANAH MEDAN." Jurnal Midwifery Update (MU) 1, no. 2 (March 11, 2020): 39. http://dx.doi.org/10.32807/jmu.v1i2.58.
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Pendahuluan; Hasil Laporan Riset Kesehatan Dasar 2013 diketahui bahwa 20,9% anak perempuan di Indonesia telah mengalami menarche diumur kurang dari 10 tahun. Membaiknya standar kehidupan berdampak pada penurunan usia menarche ke usia yang lebih muda. Tujuan; adalah untuk mengetahui hubungan gaya hidup dengan kejadian menarche dini pada remaja putri. Metode; Desain penelitian survei analitik dengan pendekatan cross sectional. Populasi dalam penelitian ini adalah siswi kelas VII, VIII, IX yang sudah menstruasi di SMP Amanah Medan sebanyak 33 siswi dan pengambilan sampel dengan total population. Instrumen dalam penelitian ini adalah kuesioner. Analisa data dilakukan dengan menggunakan uji statistik Chi-Square. Hasil; Penelitian menunjukkan dari 33 responden (100%) yang memiliki gaya hidup tidak baik sebanyak 23 responden (69,7%), dan yang baik 10 (30,3%), sedangkan yang mengalami menarche dini sebanyak 18 responden (54,6%), dan yang mengalami menarche normal sebanyak 15 (45,4%) dengan hasil p value 0,001< 0,05. Kesimpulan; Ada Hubungan Antara Gaya Hidup Dengan Kejadian Menarche Dini Pada Remaja Putri Di SMP Amanah Medan. Background: The results of the 2013 Basic Health Research Report revealed that 20.9% of girls in Indonesia had experienced menarche at less than 10 years of age. The improvement in living standards has resulted in a decrease in the age of menarche to a younger age. Objective: is to determine the relationship of lifestyle with the incidence of early menarche in adolescent girls. Method: Analytical survey research design with cross sectional approach. The population in this study were students of class VII, VIII, IX who had menstruated at Amanah Medan Middle School as many as 33 female students and took samples with a total population. The instrument in this study is a questionnaire. Data analysis was performed using Chi-Square statistical test. Result: The study showed that 33 respondents (100%) had a bad lifestyle as many as 23 respondents (69.7%), and a good 10 (30.3%), while those who experienced early menarche were 18 respondents (54.6 %), and those who experienced normal menarche were 15 (45.4%) with the results of p value 0.001 <0.05. Conclusion: There is a relationship between lifestyle and the incidence of early menarche in adolescent girls at Amanah Medan Middle School.
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Hidayat, Erwin Yudi, and Muhammad Farhan Radiffananda. "Pengenalan Tanda Tangan Menggunakan Learning Vector Quantization dan Ekstraksi Fitur Local Binary Pattern." CogITo Smart Journal 5, no. 2 (December 19, 2019): 123. http://dx.doi.org/10.31154/cogito.v5i2.180.123-136.
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Tanda tangan merupakan salah satu biometrik pada karakteristik perilaku yang digunakan untuk mengenali seseorang sebagai sistem identifikasi. Meskipun unik, banyak terjadi kasus tanda tangan yang disalahgunakan dengan cara dipalsukan. Tidak mudah mengenali tanda tangan yang palsu dengan tanda tangan asli. Penelitian ini menerapkan algoritma Learning Vector Quantization, deteksi tepi Sobel, dan ekstraksi fitur Local Binary Pattern untuk mengidentifikasi tanda tangan. Hasil penelitian menunjukkan, jumlah data citra, iterasi, dan learning rate mempengaruhi akurasi dan waktu proses identifikasi. Dari percobaan yang dilakukan pada parameter yang berbeda-beda, akurasi yang didapat adalah 68% pada data latih dan pada data uji sebesar 54,6%.Kata kunci—identifikasi, Learning Vector Quantization, tanda tangan, pengenalan pola
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Fitriana, Sintya Malra nur, Ida Chairanna Mahirawatie, and Agus Marjianto. "MOTIVASI IBU HAMIL TENTANG KEBERSIHAN GIGI DAN MULUT DI PUSKESMAS NGUMPAKDALEM BOJONEGORO." Jurnal Skala Kesehatan 12, no. 1 (January 6, 2021): 33–41. http://dx.doi.org/10.31964/jsk.v12i1.271.
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Masalah penelitian ini tingginya angka persentase karies gigi ibu hamil di Puskesmas Ngumpakdalem Kecamatan Dander Bojonegoro yaitu sebesar 60,94% dari target bebas karies 54,6%. Tujuan penelitian ini diketahuinya motivasi ibu hamil tentang kebersihan gigi dan mulut di Puskesmas Ngumpakdalem Kecamatan Dander Bojonegoro. Metode penelitian yang digunakan deskriptif. Sasaran yang terlibat dalam penelitian ini adalah 30 orang ibu hamil yang berusia 20-30 tahun. Instrument yang digunakan dalam penelitian adalah kuesioner. Hasil penelitian menunjukkan bahwa motivasi ibu hamil tentang kebersihan gigi dan mulut di Puskesmas Ngumpakdalem Kecamatan Dander Bojonegoro tahun 2020 dalam kategori kuat. Kesimpulan ibu hamil telah memiliki motivasi untuk menjaga kebersihan gigi dan mulut.
Kata kunci : Motivasi, Kebersihan Gigi dan Mulut, Ibu Hamil
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Hariandja, Evo S., Togar M. Simatupang, Reza A. Nasution, and Dwi Larso. "Dynamic Marketing and Service Innovation for Service Excellence." Gadjah Mada International Journal of Business 16, no. 2 (June 28, 2014): 143. http://dx.doi.org/10.22146/gamaijb.5461.
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This study aims at creating a framework describing how the interaction capabilities between dynamic marketing and service innovation can influence service excellence. In this study market sensing, market learning, market targeting or positioning are classified as dynamic marketing capabilities (DMC), while sensing, seizing, and transformi ng are classified as service innovation capabilities (SIC). Hence, the drivers of service excellence for the framework being developed are divided into three main categories: dynamic marketing capability, service innovation capability, and their interaction. The findings of the study on three hotels, ranging from 4-star to 5-star hotels and operating in Indonesia, suggest that both capabilities and their interaction play their roles in achieving service excellence.Abstrak: Riset ini bertujuan untuk menciptakan kerangka yang menggambarkan bagaimana kapabilitas interaksi antara pemasaran dinamik dan inovasi jasa dapat mempengaruhi keunggulan layanan. Dalam riset ini, penginderaan pasar, pembelajaran pasar, target pasar serta positioning diklasifikasikan sebagai kapabilitas pemasaran dinamik (DMC), sementara penginderaan (sensing), merebut (seizing), dan transforming diklasifikasikan sebagai kapabilitas inovasi jasa (SIC). Oleh karena itu, penggerak keunggulan layanan untuk kerangka yang dikembangkan dibagi menjadi tiga kategori utama: kapabilitas pemasaran dinamik, kapabilitas inovasi jasa, dan interaksi diantara kedua kapabilitas. Temuan studi pada tiga hotel yang dijadikan sebagai studi kasus di hotel bintang 4 (empat) dan 5 (lima) yang beroperasi di Indonesia, menunjukkan bahwa kedua kapabilitas dan interaksinya memainkan peran mereka dalam mencapai keunggulan layanan.
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Aji, Daniel Nugraha, Christopher Silman, Citra Aryudi, Cynthia Cynthia, Centauri Centauri, Damara Andalia, Desi Astari, et al. "Faktor–Faktor yang Berhubungan dengan Kualitas Hidup Pasien Thalassemia Mayor di Pusat Thalassemia Departemen Ilmu Kesehatan Anak RSCM." Sari Pediatri 11, no. 2 (November 25, 2016): 85. http://dx.doi.org/10.14238/sp11.2.2009.85-9.
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Latar belakang. Transfusi darah dan terapi kelasi yang diberikan seumur hidup pada anak dengan thalassemiamayor memberikan harapan hidup yang sama dengan anak sehat. Kualitas hidup menjadi hal yang pentingdengan bertambahnya angka harapan hidup pasien thalassemia.Tujuan. Mengetahui kualitas hidup anak dengan thalassemia mayor di Pusat Thalassemia Departemen IlmuKesehatan Anak FKUI-RSCM serta faktor-faktor yang berhubungan.Metode. Penelitian menggunakan rancangan cross-sectional. Pengambilan sampel dilakukan secara konsekutifpada bulan Juli 2009. Subjek penelitian adalah anak berusia 13-18 tahun di Pusat Thalassemia DepartemenIlmu Kesehatan Anak FKUI-RSCM yang datang selama periode penelitian. Penilaian kualitas hidupmenggunakan kuesioner baku PedsQL yang diisi sendiri oleh subjek. Analisis data dengan metode univariatdengan tingkat kemaknaan=0,05.Hasil. Dari 97 subjek, 49 (50,5%) memiliki kualitas hidup buruk. Sebaran usia, jenis kelamin, dan pendapatanorang tua berturut-turut didapatkan pada 53 subjek (54,6%) berusia 13-15 tahun, 49 subjek (50,5%) perempuan,dan 53 subjek (54,6%) memiliki orang tua berpendapatan menengah. Kelompok suku bangsa terbanyakadalah Sunda-Sunda (32%). Perubahan fisis dialami oleh 78% subjek yang terdiri dari facies Cooley (58%),hiperpigmentasi (64%), dan perut membuncit (26%). Faktor yang berhubungan dengan kualitas hidup adalahtingkat pendapatan orang tua (p=0,037), suku bangsa (p=0,019), dan tampilan facies cooley (p=0,006).Kesimpulan. Separuh anak dengan thalassemia mayor di Pusat Thalassemia RSCM (50,5%) memiliki kualitashidup yang buruk. Kualitas hidup tersebut berhubungan dengan tingkat pendapatan orang tua, suku, dantampilan facies Cooley.
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Hardinata, Wayan, La Karimuna, and Nur Asyik. "Analisis Kualitatif dan Kuantitatif Kandungan Formalin Pada Produk Terasi (Shrimp Paste) yang Diperdagangkan di Pasar Sentral Kota dan Pasar Sentral Wua-Wua." Edible: Jurnal Penelitian Ilmu-ilmu Teknologi Pangan 8, no. 1 (June 11, 2021): 45. http://dx.doi.org/10.32502/jedb.v8i1.3449.
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Penelitian ini bertujuan untuk mengetahui kandungan formalin pada terasi yang diperdagangkan di Pasar Sentral Kota dan Pasar Sentral Wua-Wua. Metode analisis yang digunakan yaitu metode Fenilhidrazin dan uji kuantitatif (Metode Titrasi). Uji kualitatif bertujuan untuk mengetahui ada tidaknya formalin pada terasi, sedangkan uji kuantitatif bertujuan untuk mengetahui berapa kadar formalin yang terkandung pada terasi yang diperdagangkan di Pasar Sentral Kota dan Pasar Sentral Wua-Wua. Jenis penelitian ini yaitu deskriptif kualitatif dan kuantitatif. Hasil penelitian ini memberikan informasi bahwa sampel yang diambil dari 6 sampel Pasar Sentral Kota dan Pasar Sentral Wua-Wua 5 sampel positif mengandung formalin. Rata-rata persentase kadar formalin di lokasi Pasar Sentral Kota (A2) sebesar 77 mg/kg dan 54,6 mg/kg (A3). Pasar Sentral Wua-Wua (B1) 60 mg/kg, (B2) 66,7 mg/kg dan (B3) 107,2 mg/kg. Hasil penelitian menghasilkan simpulan terdeteksinya penggunaan formalin pada 5 sampel produk terasi yang beredar di lokasi Pasar Sentral Kota dan Pasar Sentral Wua-Wua kota Kendari.
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Zhou, Chun, Edward S. Crockett, Lynn Batten, Ivan F. McMurtry, and Troy Stevens. "Pulmonary vascular dysfunction secondary to pulmonary arterial hypertension: insights gained through retrograde perfusion." American Journal of Physiology-Lung Cellular and Molecular Physiology 314, no. 5 (May 1, 2018): L835—L845. http://dx.doi.org/10.1152/ajplung.00201.2017.
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Here, we tested the hypothesis that severe pulmonary arterial hypertension impairs retrograde perfusion. To test this hypothesis, pulmonary arterial hypertension was induced in Fischer rats using a single injection of Sugen 5416 followed by 3 wk of exposure to 10% hypoxia and then 2 wk of normoxia. This Sugen 5416 and hypoxia regimen caused severe pulmonary arterial hypertension, with a Fulton index of 0.73 ± 0.07, reductions in both the pulmonary arterial acceleration time and pulmonary arterial acceleration to pulmonary arterial ejection times ratio, and extensive medial hypertrophy and occlusive neointimal lesions. Whereas the normotensive circulation accommodated large increases in forward and retrograde flow, the hypertensive circulation did not. During forward flow, pulmonary artery and double occlusion pressures rose sharply at low perfusion rates, resulting in hydrostatic edema. Pulmonary arterial hypertensive lungs possessed an absolute intolerance to retrograde perfusion, and they rapidly developed edema. Retrograde perfusion was not rescued by maximal vasodilation. Retrograde perfusion was preserved in lungs from animals treated with Sugen 5416 and hypoxia for 1 and 3 wk, in lungs from animals with a milder form of hypoxic hypertension, and in normotensive lungs subjected to high outflow pressures. Thus impaired retrograde perfusion coincides with development of severe pulmonary arterial hypertension, with advanced structural defects in the microcirculation.
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Reimer, F. "Von den Prinzipien psychiatrischer Begutachtung bis zur forensischen Psychiatrie." NeuroTransmitter 27, no. 2 (February 2016): 56. http://dx.doi.org/10.1007/s15016-016-5469-8.
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Hein, Nadine, Sean O'Brien, Denis Drygin, Simon J. Harrison, Amit Khot, Carleen Cullinane, Matthews Geoff, et al. "Inhibition Of RNA Polymerase I Transcription By CX-5461 As a Therapeutic Strategy For The Cancer-Specific Activation Of p53 In Highly Refractory Haematological Malignancies." Blood 122, no. 21 (November 15, 2013): 3941. http://dx.doi.org/10.1182/blood.v122.21.3941.3941.
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Abstract Malignant transformation is commonly associated with dysregulated ribosome biogenesis and for more than 100 years, pathologists have utilized the increase in size and number of nucleoli, the site of ribosome biogenesis, as a marker for aggressive malignancies (Hein et al., Trends in Molecular Medicine, 2013). Recently we demonstrated that hyperactivated RNA Polymerase I (Pol I) transcription, a rate limiting step in ribosome biogenesis, can be specifically targeted by the small molecule inhibitor, CX-5461 (Drygin et al., Cancer Research, 2011; Bywater et al. Cancer Cell, 2012). When evaluated for its anti-proliferative activity against a panel of genetically diverse human cancer cell lines, those derived from p53 wild type hematological malignancies were the most sensitive (Drygin et al., Cancer Research, 2011). Evaluation of whether Pol I transcription inhibition could serve as therapeutic strategy in vivo revealed that CX-5461 administration significantly prolongs the overall survival of Em-Myc lymphoma bearing mice. This survival advantage was associated with rapid activation of the ribosomal protein (Rp)-MDM2-p53 nucleolar stress response (Deisenroth et al., Oncogene, 2010) and subsequent induction of tumour cell-specific p53-dependent apoptosis; importantly the wild type B-cell population was maintained and did not activate p53 pathways (Bywater et al. Cancer Cell, 2012). To explore the therapeutic potential of Pol I transcription inhibition via CX-5461 in hematological malignancies refractory to standard chemotherapy, we employed mouse models of highly aggressive MLL-driven Acute Myeloid Leukemia (AML) (MLL/AF9 + Nras and MLL/ENL + Nras) (Zuber et al., Genes Dev, 2009) and V*κ-Myc-driven Multiple Myeloma (MM) (Chesi et al. Cancer Cell, 2009). CX-5461 administration significantly increased the overall survival time of AML-bearing mice (MLL/ENL Nras median 17 days for vehicle vs 36 days for drug, P<0.0001 (Figure 1); MLL/AF9 Nras median 15 days for vehicle vs 23 days for drug, P 0.0009) without severe adverse effects. The extended survival of MLL-driven AML bearing mice was associated with acute activation of p53, induction of cell death and an aberrant G2/M cell cycle progression, which consequently delayed tumour progression as monitored by bioluminescence-imaging and white blood cell counts (WBC). In contrast to CX-5461, standard-therapy with a regime containing Cytarabine/Doxorubicin (5:3) failed to induce p53 in MLL/ENL Nras AML-bearing mice, resulting in a significantly lower survival advantage as compared to animals treated with CX-5461 therapy. Figure 1Figure 1. In ongoing experiments with MM-bearing mice, chronic CX-5461 administration robustly reduced the secretion of serum monoclonal Ig, as detected by serum protein electrophoresis (SPEP), and significantly prolonged the overall survival time (Figure 2) (V*κ-Myc median >160 days for drug vs, 103.5 days for vehicle, ongoing) demonstrating that CX-5461 exhibits potent anti-tumour activity in MM model. Analysis of the molecular mechanism responsible for the therapeutic benefit of CX-5461 in MM is ongoing but appears to involve both p53 mediated apoptosis and aberrant cell cycle progression. Figure 2Figure 2. These data demonstrate that hyperactivated Pol I transcription can be successfully targeted through small molecule inhibitors to treat models of human AML and MM that are refractory to standard therapy. Based on these and previously published results (Bywater et al., Cancer Cell, 2012), we have recently initiated a first-in-human, phase I, dose escalation clinical trial of this first-in-class drug, CX-5461 in patients with advanced hematological malignancies. The toxicity, response, pharmacokinetic and co-relative data from this trial will offer valuable insights as to whether inhibition of ribosome synthesis might offer a new non-genotoxic therapeutic approach in the fight against cancers, which are highly refractory to standard therapies. Disclosures: O'Brien: Senhwa Biosciences, Inc: Employment.
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Green, WQ, and JD Coleman. "Den Sites of Possums, Trichosurus-Vulpecula, and Frequency of Use in Mixed Hardwood Forest in Westland, New-Zealand." Wildlife Research 14, no. 3 (1987): 285. http://dx.doi.org/10.1071/wr9870285.
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Forty-seven common brushtail possums, Trichosurus vulpecula, were radiotracked to 282 dens on 546 occasions. Just over half of all dens were in living trees; the remainder were evenly distributed between dead standing stems (including short stumps) and logs, with a few (3%) in banks and rock fissures. Of all the den entrances, 73% were at, or below, ground level amongst root systems or in logs. Although dead standing stems (over 25 cm d.b.h.) made up only 4% of standing stems in forest below 500 m altitude, they contained 41% of the dens. Each possum probably used between 10 and 15 dens each year. There were no differences in den choice and frequency of use between mature males and females. Den choice by matures and immatures was similar, but mature possums used dens in 'dead' sites more than did immatures. The implications of dens in the transmission of bovine tuberculosis are discussed.
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Ependi, Radias, Tari Okta Puspitasari, and Nur Ika Sandi Pratiwi. "Identifikasi Sikap Implikasi Sosial dari Fisika, Normalitas Ilmuwan, dan Adopsi Sikap Ilmiah." Attractive : Innovative Education Journal 2, no. 1 (April 27, 2020): 133. http://dx.doi.org/10.51278/aj.v2i1.32.
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The purpose of this study was to find out how the attitude of students of SMAN 8 Jambi City towards Physics subjects. This type of research is a quantitative study with a survey research design. Data collection techniques used a questionnaire or questionnaire and used a 5-point Likert scale. This research involved 174 students of SMAN 8 Kota Jambi. Data analysis in this study used descriptive statistics. Indicators used in this study are the Social Implications of Physics, Scientific Normality and Adoption of Scientific Attitudes. The analysis results obtained on indicators of the social implications of physics are good with 54.6% presentation. Indicator of attitude toward scientific normality is sufficient with 61.5% presentation, and indicator of scientific attitude adoption is good with presentation of 49.4%.
Keywords: Attitude, Social Implications Of Physics, Scientific Normality, Adoption Of Scientific Attitudes.
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Nada, Qothrun, Cahya Ridhuandi, Puji Santoso, and Dwi Apriyanto. "Speech Recognition dengan Hidden Markov Model untuk Pengenalan dan Pelafalan Huruf Hijaiyah." JURNAL Al-AZHAR INDONESIA SERI SAINS DAN TEKNOLOGI 5, no. 1 (March 30, 2019): 19. http://dx.doi.org/10.36722/sst.v5i1.319.
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<p><em>Abstrak</em><strong> </strong>- <strong>Pelajaran utama dalam membaca Al Qur'an adalah mengenali dan </strong><strong>melafalkan</strong><strong> huruf-huruf Hijaiyah. Beberapa fakta menunjukkan bahwa pengucapan yang salah dapat memengaruhi makna secara har</strong><strong>a</strong><strong>fiah. <em>Speech Recognition</em>, sebagai teknologi saat ini, dapat digunakan untuk memeriksa kesalahan dalam melafalkan surat Hijaiyah melalui pengenalan suara atau ucapan. Itu dapat dikonversi menjadi data yang dapat dipahami oleh sistem. Tujuan dari penelitian ini adalah untuk menerapkan <em>Speech Recognition</em> dengan <em>Hidden Markov Model</em> untuk pelafalan huruf Hijaiyah ketika belajar membaca Alquran. Pengenalan ucapan dan Model Hidden Markov dilakukan untuk mengembangkan sistem antar</strong><strong> </strong><strong>muka mesin berbasis suara. Dalam penelitian ini juga menggunakan metode <em>Fast Fourier Transform</em> (FFT) untuk mengekstraksi sifat. <em>Hidden Markov Model</em> (HMM) yang digunakan dalam proses pelatihan. Juga, menghasilkan karakteristik khusus untuk setiap huruf Hijaiyah. Dan kemudian, <em>Euclidean Distance</em> (ED) untuk klasifikasi akhir dalam mendeteksi pelafalan huruf Hijaiyah. Hasil penelitian menunjukkan bahwa hasil tes huruf Hijaiyah pada tingkat akurasi yang sama adalah 100%, sedangkan pengujian huruf yang berbeda adalah 54,6%. Dengan demikian, penelitian ini akan memberikan kontribusi kepada siswa yang sedang belajar membaca Al-Qur'an untuk dapat mengenali dan me</strong><strong>lafalkan</strong><strong> huruf-huruf Hijaiyah</strong><strong><em>.</em></strong></p><p><em>Abstract</em> – <strong>The main lesson in reading the Al Qur'an is recognizing and reciting the letters Hijaiyah. Some facts show that incorrect pronunciation can affect meaning literally. Speech Recognition, as the current technology, can be used to check the mistakes in pronouncing the Hijaiyah's letter through recognizing the voice or speech. It can convert into data that can be understood by the system. The purpose of this study is to implement Speech Recognition with Hidden Markov Model for Hijaiyah letter pronunciation when learning to read the Qur'an. Speech recognition and Hidden Markov Models were carried out to develop a sound-based machine interface system. In this study also used the Fast Fourier Transform (FFT) method to extract traits. Hidden Markov Model (HMM) used in the training process. Also, produced the especially characteristics for each letter of Hijaiyah. And then, Euclidean Distance (ED) for the final classification in detecting Hijaiyah letter pronunciation. The results of the study show that the results of the Hijaiyah letter test on the same level of accuracy are 100%, while the testing of different letters is 54.6%. Thus, this study will contribute to students who are learning to read Al-Qur'an to be able to recognize and recite the Hijaiyah letters</strong><strong><em>.</em></strong></p><p><strong><em>Keywords</em></strong> - <em>Speech Recognition, Hidden Markov Model, Recognizing, Reciting, Letter Hijaiyah </em></p>
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Andi, Dede. "Pengaruh Disiplin dan Motivasi Terhadap Produktivitas Karyawan Pada PT. Boga Produce di Tangerang." Journal of Education, Humaniora and Social Sciences (JEHSS) 3, no. 2 (December 2, 2020): 637–43. http://dx.doi.org/10.34007/jehss.v3i2.383.
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This study aims to determine the effect of discipline and motivation on employee productivity at PT. Boga Produce in Tangerang. The method used is explanatory research with analysis techniques using statistical analysis with regression testing, correlation, determination and hypothesis testing. The results of this study, discipline has a significant effect on employee productivity by 39.2%, the hypothesis test is obtained t count> t table or (6,719> 1,994). Motivation has a significant effect on employee productivity by 54.6%, hypothesis testing is obtained t count> t table or (9.173> 1.994). Discipline and motivation simultaneously have a significant effect on employee productivity with the regression equation Y = 8.676 + 0.254X1 + 0.543X2 and the contribution of the influence is 57.9%, the hypothesis test obtained F count> F table or (47.424> 2.740).
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Yanuar, Padang, Iman Mujiarto, and Yoeli Janto. "PENINGKATAN NILAI KEKERASAN BAJA C-Mn DENGAN METODE QUENCHING DAN TEMPERING." Simetris: Jurnal Teknik Mesin, Elektro dan Ilmu Komputer 9, no. 1 (April 1, 2018): 61–66. http://dx.doi.org/10.24176/simet.v9i1.1706.
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Perlakuan panas quenching dan tempering telah lama diterapkan pada baja untuk menghasilkan kombinasi antara kekuatan dan ketangguhan yang baik dengan struktur mikro martensite. Sifat baja seperti kekerasan yang tinggi dengan kombinasi ketangguhan yang baik membuat baja menjadi pilihan utama untuk material armor (tahan peluru). Tujuan penelitian ini melakukan kajian perubahan sifat mekanis baja komersial (baja C-Mn) akibat proses quenching dan tempering untuk dapat diaplikasikan sebagai baja armor. Pemanasan pada temperatur austenit 900 °C dengan penahanan selama 45 menit kemudian dilakukan quenching pada media air dilanjutkan tempering 175 °C selama 30 menit didapatkan nilai kekerasan tertinggi sebesar 546 BHN dengan dominasi struktur mikro martensite yang terbentuk.
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Jacobson, Alex. "Kieferorthopädische forderungen für den verschluβ der kieferspalten." American Journal of Orthodontics and Dentofacial Orthopedics 92, no. 5 (November 1987): 447. http://dx.doi.org/10.1016/0889-5406(87)90273-3.
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Souza, Amaury De, and Débora Aparecida da Silva Santos. "ANÁLISE DAS COMPONENTES PRINCIPAIS NO PROCESSO DE MONITORAMENTO AMBIENTAL." Nativa 6, no. 6 (November 5, 2018): 639. http://dx.doi.org/10.31413/nativa.v6i6.6453.
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O presente trabalho apresenta os resultados da medição das concentrações de ozônio, óxidos de nitrogênio (NO, NO2 e NOx) e SO2 em ar ambiente em paralelo com o registro dos parâmetros meteorológicos: temperatura, radiação solar, umidade relativa, pressão barométrica, velocidade e direção do vento durante o ano de 2015. As medições foram efetuadas na estação de medição situada dentro do campus da Universidade Federal de Mato Grosso do Sul. Os resultados são apresentados neste trabalho como valores médios em relação ao tempo do dia. Diversas correlações da concentração de ozônio vs. observação atmosféricos foram feitas, juntamente com a Análise de Componentes Principais. A análise estatística dos dados obtidos, com base na Análise de Componentes Principais (ACP), levou a que 73,2% da variância dos valores medidos pudessem ser descritos com quatro fatores. Foi determinado um alto grau de intercorrelação de NOx. Estes poluentes foram todos agrupados no fator 1 e 2, que descreveu 54,6% de variâncias dos valores medidos.Palavras-chave: poluentes, ozônio, óxidos de nitrogênio. PRINCIPAL COMPONENT ANALYSIS IN THE ENVIRONMENTAL MONITORING PROCESS ABSTRACT: The present work presents the results of measuring the concentrations of ozone, nitrogen oxides (NO, NO2 and NOx) and SO2 in ambient air in parallel with the recording of meteorological parameters: temperature, solar radiation, relative humidity, barometric pressure, velocity and Wind direction during the year 2015. The measurements were taken at the measuring station located inside the campus of the Federal University of Mato Grosso do Sul. The results are presented in this work as mean values in relation to the time of day. Several correlations of the ozone concentration vs. Atmospheric observations were made along with Principal Component Analysis. Statistical analysis of the data obtained, based on Principal Component Analysis (PCA), led to 73.2% of the variance of the measured values could be described with four factors. A high degree of NOx intercorrelation was determined. These pollutants were all grouped in factor 1 and 2, which described 54.6% of variances of the measured values.Keywords: pollutants, ozone, nitrogen oxides.
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Eroglu, A., G. G. Ceylan, E. Ozturk, A. Yalcin, B. Yalcin, and D. Karasoy. "THE EFFICACY OF TISSUE FACTOR −603A/G AND +5466A>G POLIMORPHISMS AT THE DEVELOPMENT OF VENOUS THROMBOEMBOLISM IN CANCER PATIENTS." Experimental Oncology 38, no. 3 (September 22, 2016): 187–90. http://dx.doi.org/10.31768/2312-8852.2016.38(3):187-190.
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Background and Aim: Venous thromboembolism (VTE) is one of the most common complications in cancer patients. Although factor V Leiden (FVL) is the most common genetic defect causing thrombosis, the impact of gene abnormalities on thrombotic tendency in cancer patients remains poorly explored. Tissue factor (TF) is a major physiologic initiator of blood coagulation. This is the first study regarding the association of TF gene −603A/G and +5466A>G polymorphisms with VTE in malignancy. Materials and Me thods: The study consists of two groups: cancer patients with VTE were included as Group 1 (n = 46); Group 2 comprises 196 cancer patients without VTE. Restriction fragment length polymorphism method was used for the detection of polymorphisms of TF −603A/G in the 5՛upstream region and TF 5466A/G in intron 2. FVL, PT G20210A and MTHFR C677T polymorphisms were determined by using commercially available Light Cycler kits. The genotype and allele frequencies between the groups were compared using χ2 or Fisher exact test, if appropriate. Results: No differences were observed in the distribution of TF gene −603A/G genotype frequencies between the groups. Although a slightly increased incidence of +5466GA genotype was in Group 1 (17.4% vs 11.2%), it did not achieve statistical significance. The prevalence of FVL was significantly greater in Group 1 compared with Group 2 (41.3% vs 4.1%, p < 0.05). Difference in frequency of 677TT+CT (MTHFR) + 5466GG (TF) genotypes combination was found in women of two investigated Groups (p < 0.05). No differences were also in genotypes and allele frequencies of MTHFR C677T and PT G20210A between two Groups (p > 0.05). Conclusions: The present study did not show significant association of TF gene −603A/G and +5466A>G polymorphisms with VTE in malignancy, however, further larger studies including different ethnic population are needed to confirm our findings.
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Sari, Titis Nistia, Dhea Zatira, and Gerry Ganika. "FAKTOR MAKROEKONOMI TERHADAP INDEKS HARGA SAHAM SUBSEKTOR KEUANGAN YANG TERDAFTAR DI BEI." Jurnal Ilmu Keuangan dan Perbankan (JIKA) 9, no. 1 (May 10, 2020): 13–26. http://dx.doi.org/10.34010/jika.v9i1.3064.
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This article is to examine the effect of the BI Rate, Inflation and Exchange Rates on the stock price indexes of the financial sub-sectors listed on the Indonesia Stock Exchange in the period November 2015 to October 2019. Data analysis techniques used in this study are regression models with quantitative methods. Test results prove that the negative BI Rate for IHSK and H1 is accepted. Negative inflation in FSPI and H2 is accepted. Positive exchange rates on the IHSK and H3 are accepted. The BI Rate, Inflation, and Exchange Rates received simultaneously against IHSK and H4 are accepted. The magnitude of the effect on R squared was 54.6%, while the remaining 45.4% was accepted by other variables not approved in this study.
Keywords: BI Rate, Inflation, Exchange Rates, Financial sub-sector Stock Price Index (FSPI)
Artikel ini adalah untuk memeriksa dampak suku bunga BI, nilai inflasi dan nilai tukar, terhadap harga harga dibursa saham pada sub sector keuangan yang terdaftar di bursa saham Indonesia untuk periode November 2015 sampai dengan Oktober 2019, tehnik penganalisaaan data yang digunakan pada studi ini adalah model mundur dengan metode kuantitatif. Hasil tesnya membuktikan bahwa suku bunga negatif BI untuk IHSK dan H1 dapat diterima. Inflasi negatif pada FSPI dan H2, dapat diterima.Nilai tukar yang positif pada IHSK dan H3 dapat diterima. Suku bunga BI, inflasi dan nilai tukar yang diterima secara berkesinambungan terhadap IHSK dan H4 dapat diterima. Daya Tarik dari dampak pada kotak R adalah 54.6% sementara sisanya yang 45.4% diterima oleh variabel lain yang tidak dibahas pada studi ini.
Kata Kunci: Suku Bunga BI, Inflasi, Nilai Tukar, Indeks Harga Saham sub sektor Keuangan (IHSK)
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Akbar, Irfan Rizka, Puji Harjianto, and Hadi Winata. "Pengaruh Disiplin Kerja Dan Motivasi Terhadap Kinerja Karyawan Pada PT. POS Indonesia Kantor Cabang Pondok Aren." Jurnal Ilmiah PERKUSI 1, no. 2 (June 10, 2021): 232. http://dx.doi.org/10.32493/j.perkusi.v1i2.11038.
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Penelitian ini bertujuan untuk mengetahui pengaruh disiplin kerja dan motivasi terhadap kinerja karyawan pada PT. Pos Indonesia Kantor Cabang Pondok Aren. Metode yang digunakan adalah explanatory research dengan teknik analisis menggunakan analisis statistik dengan pengujian regresi, korelasi, determinasi dan uji hipotesis. Hasil penelitian ini disiplin kerja berpengaruh signifikan terhadap kinerja karyawan sebesar 45,8%, uji hipotesis diperoleh t hitung > t tabel atau (6,996 > 2,002). Motivasi berpengaruh signifikan terhadap kinerja karyawan sebesar 35,5%, uji hipotesis diperoleh t hitung > t tabel atau (5,652 > 2,002). Disiplin kerja dan motivasi secara simultan berpengaruh signifikan terhadap kinerja karyawan dengan persamaan regresi Y = 10,959 + 0,419X1 + 0,322X2 dan kontribusi pengaruh sebesar 54,6%, uji hipotesis diperoleh F hitung > F tabel atau (34,339 > 2,770).
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Asril, Aprinal Adila, Yustini Yustini, and Hadria Oktavia. "Perancangan Dan Realisasi Antena Mikrostrip Monopole Segiempat Pada Frekuensi 546 Mhz Untuk Aplikasi Dvb-T." Elektron : Jurnal Ilmiah 11, no. 1 (June 30, 2019): 18–28. http://dx.doi.org/10.30630/eji.11.1.96.
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Antena mikrostrip adalah suatu konduktor metal yang menempel diatas groundplane yang diantarannya terdapat bahan dielektrik. Antena mikrostrip terdiri atas 3 bagian utama yaitu patch, substrate dan groundplane. Antena mikrostrip yang dapat digunakan dalam konsep aplikasi DVB-T. Sistem DVB-T (Digital Video Broadcasting Terestrial), merupakan sistem penyiaran langsung dari pemancar bumi (terrestrial). Pada penelitian ini dibuat antena mikrostrip monopole untuk DVB-T dengan menggunakan PCB double layer dan software Zeland. Antena ini dirancang pada frekuensi 546 MHz. Bahan yang digunakan adalah PCB epoxy (FR4) double layer dengan ketebalan bahan 1.6 mm dan konstanta dielektrik sebesar 4.7 mm. Antena mikrostrip tersebut diuji untuk mendapatkan nilai frekuensi resonansi, bandwidth, VSWR, HPBW, Gain dan polaradiasi yang kemudian hasilnya dibandingkan dengan hasil simulasi menggunakan software Zeland Program Manager (IE3D). Pada hasil pengukuran antena diperoleh hasil untuk antena mikrostrip diantaranya nilai return loss = -25 dB pada frekuensi = 545 MHz, bandwidth = 140 MHz, dengan nilai VSWR = 1.48 dB, HPBW = 75o dan polaradiasi berbentuk Bidirectional.
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Amstrup, Niels. "Jürgen Habermas, Teorien om den kommunikative handlen, Aalborg: Aalborg Universitetsforlag, 1996, 546 s., kr. 286,00." Politica 28, no. 4 (January 1, 1996): 508. http://dx.doi.org/10.7146/politica.v28i4.68079.
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Kinas, Sven. "Zwangssterilisationen in Thüringen und Württemberg 1933–1945." Das Gesundheitswesen 82, no. 02 (August 27, 2019): 126–31. http://dx.doi.org/10.1055/a-0955-5436.
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ZusammenfassungBei der Durchführung des Gesetzes zur Verhütung erbkranken Nachwuchses vom 14 Juli 1933 (GzVeN) kam den an den Staatlichen Gesundheitsämtern tätigen Amtsärzten eine Schlüsselfunktion zu. Sie verfassten einen Großteil der Sterilisationsanzeigen, stellten die überwiegende Mehrheit der Sterilisationsanträge und wirkten als Gutachter oder Richter an den Entscheidungen der Erbgesundheitsgerichte mit. Der Beitrag präsentiert genaue Zahlen zu den Folgen der Sterilisationspolitik in Thüringen und Württemberg und benennt die Ursachen für die erheblichen Unterschiede, die bei der Durchführung des GzVeN in diesen Ländern auszumachen sind.
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Pertiwi, Nadia Yuli, and Ice Yulia Wardani. "TINGKAT STRES KERJA DAN STRATEGI KOPING GURU SD DALAM IMPLEMENTASI KURIKULUM 2013." Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal 9, no. 2 (April 29, 2019): 155–64. http://dx.doi.org/10.32583/pskm.9.2.2019.155-164.
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Kualitas guru sangat mempengaruhi pendidikan pada setiap jenjangnya termasuk jenjang sekolah dasar. Profesi guru termasuk salah satu pekerjaan yang memiliki tingkat stres kerja yang tinggi. Salah satu penyebab stres adalah kurikulum pendidikan.Penelitian ini bertujuan untuk mengetahui gambaran tingkat stres kerja dan strategi koping guru sekolah dasar negeri dalam implementasi kurikulum 2013 di Kecamatan Bogor Tengah Kota Bogor. Penelitian ini menggunakan desain penelitian deskriptif kuantitatif sederhana dengan pendekatan cross sectional. Penelitian ini melibatkan 222 guru di sekolah dasar negeri Kecamatan Bogor Tengah yang dipilih menggunakan purposive sampling. Hasil penelitian ini menggambarkan bahwa sebesar (81,5%) guru mengalami stres sedang. Penjabaran dari dimensi stres kerja yaitu dimensi peran kerja individu (ORQ), dimensi beban kerja individu (PSQ), dan dimensi sumber daya yang dimiliki (PRQ) menunjukkan bahwa mayoritas guru mengalami stres sedang pada ketiga kategori tersebut. Adapun jenis strategi koping yang paling sering digunakan adalah problem focused coping (54,6%). Hasil penelitian ini diharapkan agar perawat dapat bekerja sama dengan pihak sekolah dasar negeri untuk memfasilitasi kegiatan yang dapat meminimalkan kejadian stres kerja dengan penggunaan strategi koping yang tepat.
Kata kunci: Guru sekolah dasar negeri, stres kerja, kurikulum 2013, strategi koping
THE LEVEL OF STRESS AND COPING STRATEGY OF ELEMENTARY SCHOOL TEACHERS IN IMPLEMENTATION OF CURRICULUM 2013
ABSTRACT
Teachers quality is greatly influence education at the whole level of education including elementary school level. Teachers are one of the jobs with high levels of work stress. One of the causes of work stress is educational curriculum. This study aims to determine the level of stress and coping strategy of elementary school teachers in implementation of curriculum 2013 in Bogor Central District, Bogor. The design in this research used descriptive quantitative with cross sectional approach. This study involved 222 elementary schools teachers in Bogor Central District selected by purposive sampling. The results of this study illustrate the majority of elementary schools teachers in Bogor Central District (81,5%) experience moderate stress. Each dimension of work stress, occupational role (ORQ), personal strain (PSQ) and personal resources (PRQ) show that the majority of teachers experience moderate stress. The type of coping strategy that is most often used by elementary schools teachers in Bogor Central Districtis is problem focused coping (54,6%). The results of this study recommend nurses to be able for collaboration with school to facilitate activities that could reduce stress and use appropriate coping strategies.
Keywords: Elementary School Teacher, work stress, curriculum 2013, coping strategy
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Susanti, Elva, and Welly Sugianto. "PENGARUH IKLIM KESELAMATAN DAN KESEHATAN KERJA TERHADAP PERILAKU KERJA AMAN PADA PEKERJA SHIPYARD BATAM." Jurnal Teknik Ibnu Sina (JT-IBSI) 4, no. 02 (March 11, 2020): 23–31. http://dx.doi.org/10.36352/jt-ibsi.v4i02.45.
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Tingginya kecelakaan kerja dapat juga dipengaruhi oleh kurangnya perilaku kerja aman. Dalam hal ini, perilaku kerja aman dapat kita lihat dari komitmen para pekerja, komitmen tersebut akan terwujud apabila lingkungan juga mendukung. Iklim keselamatan dan kinerja baik. Dalam penelitian ini akan mencari tahu apakah ada pengaruh antara iklim k3 terhadap perilaku kerja aman karyawan shipyard kota Batam, karena para pekerja yang bekerja disana memiliki tingkat resiko kecelakaan kerja yang sangat tinggi. Penelitian ini merupakan penelitian deskriptip dengan pendekatan kuantitatif, penggolahan data menggunakan SPSS 16 dengan pendekatan regresi linier. Nilai Reabilitas menggunakan alpha cronbach’s = 0.771 untuk iklim k3, sedangkan alpha cronbach’s =0.777 untuk perilaku kerja aman maka dari itu data realibel.Pada tabel coefficients nilai signifikansi sebesar 0.000 lebih kecil dari nilai 0.05 sehingga dapat disimpulkan ada pengaruh antara iklim keselamatan dan kesehatan kerja terhadap perilaku kerja aman pada pekerja shipyard Batam sebesar 54,6 % dan diperoleh persamaan Regresinya Y = 5.056 + 0.764X.
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Yulendasari, Rika, Sumbara Sumbara, and Redia Indira Putrianti. "Faktor yang mempengaruhi ibu menyapih anak di bawah usia 2 tahun." Holistik Jurnal Kesehatan 14, no. 2 (July 27, 2020): 202–9. http://dx.doi.org/10.33024/hjk.v14i2.1637.
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Practices of breastfeeding and weaning among mothers of children under 2 years old at Bandar Lampung-Indonesia Background: Weaning is a process for stopping breastfeeding gradually or at once. This process can be either because of the child herself wanting to stop breastfeeding or because the mothers desire, or by both of them for many reasons. Data from survey of health demography in Indonesia in 2017 showed that there were only 54.6% of children were receiving breastfeeding complete until 2 years old.Purpose: Know the factors of practices of breastfeeding and weaning among mothers of children under 2 years oldMethods: A quantitative research by using Cross Sectional approach. Population was all mothers who has children under two years old. Samples were 145 respondents. Data were collected by using questionnaires and anthropometry. Data were analyzed by using Chi-Square Test.Results: There were correlations of occupation (p-value 0.025 < α 0.05) and OR = 2.7, nutrition status (p-value 0.006 < α 0.05) and OR=3.5, and family support (p-value 0.002 < α 0.05) and OR= 3.1 on practices of breastfeeding and weaning among mothers of children under 2 years oldConclusion: There were practices of breastfeeding and weaning among mothers of children under 2 years old. Suggestion to health worker and provider to improve health services especially promotion program and education for essential of breastfeeding until the children complete 2 years old.Keywords: Practices; Breastfeeding; Weaning; Mothers; Children under 2 years old.Pendahuluan: Menyapih adalah proses berhentinya masa menyusui berangsur-angsur atau sekaligus. Proses itu dapat disebabkan oleh si anak itu sendiri untuk berhenti menyusu atau bisa juga dari sang ibu untuk berhenti menyusui anaknya, atau keduanya dengan berbagai alasan.Berdasarkan data dari Survey Demografi Kesehatan Indonesia (SDKI) di tahun 2017, presentase anak yang mendapatkan ASI sampai usia 2 tahun hanya sebesar 54,6%.Tujuan: Diketahui faktor - faktor yang mempengaruhi ibu menyapih anak di bawah usia 2 tahun.Metode: Penelitian kuantitatif dengan pendekatan cross sectional. Populasi pada penelitian ini adalah semua ibu yang memiliki anak di bawah usia 2 tahun. Sampel dalam penelitian ini sebesar 145 responden. Instrumen dalam penelitian ini dengan menggunakan lembar kuesioner dan antropometri. Uji statistik yang digunakan adalah uji Chi-Square.Hasil: Terdapat hubungan pekerjaan dengan penyapihan pada anak dibawah usia 2 tahun (p-value = 0,025 < α = 0,05) serta nilai OR= 2,7, status gizi (p-value = 0,006 < α = 0,05) nilai OR = 3,5, dan dukungan keluarga (p-value = 0,002 < α = 0,05) dan nilai OR=3,1. Simpulan: Ada hubungan pekerjaan, status gizi, dan dukungan keluarga dengan penyapihan pada anak dibawah usia 2 tahun. Saran bagi petugas kesehatan untuk meningkatkan pelayanan dan memberikan penyuluhan terhadap ibu menyusui mengenai pentingnya pemberian ASI samapai usia anak 2 tahun.
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Halimah, Siti, Rita Retnowati, and Herfina Herfina. "HUBUNGAN ANTARA KEPEMIMPINAN VISIONER KEPALA SEKOLAH DAN KEINOVATIFAN DENGAN EFEKTIVITAS KERJA GURU." JURNAL MANAJEMEN PENDIDIKAN 7, no. 2 (September 13, 2019): 825–32. http://dx.doi.org/10.33751/jmp.v7i2.1332.
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Penelitian ini dilakukan untuk mempelajari hubungan antara Kepemimpinan Visioner Kepala Sekolah dan Inovasi Guru dengan Efektivitas Kerja Guru. Penelitian dilaksanakan di 15 Madrasah Ibtidaiyah Swasta di Wilayah Kecamatan Cicurug Kabupaten Sukabumi Propinsi Jawa Barat pada tahun 2018 dengan sampel 105 dari populasi 142 yang diambil secara Proporsional Random Sampling. Metode yang digunakan yaitu survai dan teknik analisis data menggunakan uji statistik korelasi dan regresi linier sederhana serta regresi dan linier ganda. Hasil penelitian menghasilkan tiga kesimpulan yaitu, pertama, terdapat hubungan positif yang signifikan antara Kepemimpinan Visioner Kepala Sekolah (X1) dan Efektivitas Kerja Guru (Y) dengan koefisien korelasi ry1 = 0, 5486. Kedua, Terdapat hubungan positif yang signifikan antara variabel Inovasi (X2) dengan Efektivitas Kerja Guru (Y) dengan koefisien korelasi ry2 sebesar 0,8028 Ketiga terdapat hubungan positif signifikan antara variabel Kepemimpinan Visioner Kepala Sekolah (X1) dan Inovasi (X2) secara bersama-sama dengan Efektivitas Kerja Guru (Y) dengan koefisien korelasi Ry12 sebesar 0,8144. Berdasarkan hal-hal tersebut dapat disimpulkan bahwa Efektivitas Kerja Guru dapat ditingkatkan melalui Kepemimpinan Visioner Kepala Sekolah dan Inovasi. Kata Kunci : Kepemimpinan Visioner Kepala Sekolah, Inovasi, Efektivitas Kerja Guru.
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Indriyani, Yunita Dwi, Satrio Wicaksono Sudarman, and Ira Vahlia. "Peningkatan Kemampuan Representasi Matematis Dan Kemandirian Belajar Siswa Menggunakan Pendekatan RME." Jurnal Derivat: Jurnal Matematika dan Pendidikan Matematika 7, no. 1 (July 20, 2020): 1–10. http://dx.doi.org/10.31316/j.derivat.v7i1.712.
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The purpose of this research is to improve the mathematical representation ability and learning independence through the Realistic Mathematics Education (RME) approach in students of class XI IPS 1 SMA N 1 Pekalongan. This type of research is a classroom action research study subjects were students of class XI IPS 1 SMA N 1 Pekalongan consisting of 25 students. This can be seen from the students' mathematical representation ability in linear program material by increasing data analysis (N-Gain) from the pre-survey to the first cycle obtained an average pre-test of 59.2 and an average post-test of 64.8 so that gain 0.30 with a percentage of 30% in the low category. Furthermore, the first cycle to the second cycle obtained an average pre-test of 64.8 and an average post-test of 77.4 so that a gain of 0.53 with a percentage of 53% in the medium category. Independence of student learning from pre-survey to the first cycle with a percentage of 54.6% increased to 65.05% with a high category. Furthermore, from cycle, I to cycle II with a percentage of 65.05% increased to 82.9% with a very high category.Keywords:Mathematical Representation, Self-regulated Learning, RME
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Hamsi, Taufik, Nurlaela Rauf, and Dahlang Tahir. "Evaluasi Tingkat Kebisingan Pada SMK Darussalam Makassar." Gravitasi 20, no. 1 (July 1, 2021): 24–33. http://dx.doi.org/10.22487/gravitasi.v20i1.15526.
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Penelitian mengenai tingkat kebisingan di SMK Darussalam Makassar menggunakan alat sound level meter. Tingkat kebisingan di ukur di 5 titik. Pada penelitian ini aspek yang dianalisis adalah tingkat polusi bising dan hubungannya dengan jumlah kendaraan yang melintas di depan sekolah. Secara umum kebisingan di SMK Darussalam Makassar berada pada level dapat di terima sampai tidak dapat di terima dengan nilai berkisar 54,6 dB – 88,1 dB. Semakin kedalam letak titik pengukuran kebisingan di SMK Darussalam, maka semakin rendah pula tingkat kebisingan yang terjadi.
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AB, Ahmad. "CITRA DESTINASI DAN PENGARUHNYA TERHADAP INTENSI UNTUK BERKUNJUNG KEMBALI DI SULAWESI SELATAN SEBAGAI DESTINASI PARIWISATA." Sosiohumaniora 20, no. 3 (November 2, 2018): 207. http://dx.doi.org/10.24198/sosiohumaniora.v20i3.14050.
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Salah faktor yang memengaruhi pengembangan pariwisata adalah citra destinasi. Setiap destinasi pariwisata harus menciptakan sebuah citra yang positif untuk menarik wisatawan memiliki intensi untuk berkunjung kembali. Penelitian ini bertujuan untuk menganalisis pengaruh langsung dan tidak langsung citra kognitif terhadap intensi wisatawan untuk berkunjung kembali ke Sulawesi Selatan. Convenience sampling digunakan untuk menentukan jumlah sampel penelitian. Data dikumpulkan melalui survey, dimana kuesioner diberikan kepada 546 wisatawan dan yang memenuhi syarat untuk diolah adalah 482 kuesioner. Data dianalisis menggunakan analisis jalur. Hasil penelitian mengindikasikan bahwa citra kognitif berpengaruh langsung terhadap intensi wisatawan untuk berkunjung kembali ke Sulawesi Selatan. Citra kognitif juga berpengaruh tidak langsung terhadap intensi wisatawan untuk berkunjung kembali melalui citra afektif.
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Jacobson, Alex. "Grundlagenuntersuchung über den funktionszustand dysgnather patienten vor beginn orthopädischer therapie." American Journal of Orthodontics and Dentofacial Orthopedics 91, no. 4 (April 1987): 354. http://dx.doi.org/10.1016/0889-5406(87)90189-2.
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Schmiedel, Volker. "Multiple Sklerose und Fettsäuren – historischer und aktueller Studienstand." Erfahrungsheilkunde 68, no. 04 (August 2019): 190–93. http://dx.doi.org/10.1055/a-0969-5460.
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ZusammenfassungSchon in den 1950er-Jahren gab es Hinweise auf Zusammenhänge zwischen Fettsäuren in der Ernährung und Multipler Sklerose (MS). In den kommenden Jahrzehnten konnte dann aufgedeckt werden, über welche Mechanismen bestimmte Fettsäuren pro- oder anti-inflammatorisch wirken. Weitere Studien konnten belegen, dass die Omega-3-Fettsäuren EPA/DHA Entzündungsmediatoren senken können. Weitere Symptome wie Depression, Schübe oder Stoffwechselparameter konnten laut Studien ebenfalls gebessert werden.
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Naibaho, Frans Grovy, Nunuk Priyani, Erman Munir, and Nina Septania Damanik. "Isolasi Bakteri Penghasil Biosurfaktan Menggunakan Media yang Mengandung Pestisida Karbosulfan." Jurnal Jejaring Matematika dan Sains 2, no. 1 (October 30, 2020): 21–24. http://dx.doi.org/10.36873/jjms.2020.v2.i1.345.
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Penggunaan pestisida sintetik yang tidak terkontrol dapat menyebabkan pencemaran lingkungan karena meningggalkan senyawa pestisida di tanah dan perairan. Bioremediasi adalah salah satu cara untuk mengurangi cemaran senyawa kimia berbahaya di lingkungan dengan menggunakan mikroorganisme. Tujuan penelitian ini ialah untuk memperoleh isolat bakteri potensial penghasil biosurfaktan dari laut Belawan Sumatera Utara dan untuk mengetahui aktivitas biosurfaktannya. Isolasi bakteri dilakukan dengan menggunakan media selektif Bushnell-Hass Agar (BHA) yang mengandung 12 ppm pestisida berbahan aktif karbosulfan sebagai sumber karbon. Aktivitas biosurfaktan dilakukan dengan metode Drop collapsing test dan konsentrasi biosurfaktan dilakukan dengan metose orsinol yang dimodifikasi. Hasil penelitian menunjukkan 9 isolat berhasil diisolasi dan mampu tumbuh pada media yang mengandung karbosulfan. Aktivitas biosurfaktan tertinggi dihasilkan oleh isolat FB6 yang ditandai dengan pembentukan emulsi sebesar 5,627 mL dan produksi biosurfaktan tertinggi ditunjukkan oleh isolat FB7 dengan konsentrasi 54,6 ppm.
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Berger, Harald. "Ein bemerkenswerter spätmittelalterlicher Codex zur Philosophie, Astronomie und Medizin: Mainz, Stadtbibliothek, HS I 613." Traditio 62 (2007): 237–58. http://dx.doi.org/10.1017/s0362152900000581.
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Vor kurzem habe ich den Cod. 5461 der Österreichischen Nationalbibliothek, Wien, beschrieben, in dem unter anderem dieQuaestiones super arte veterides Henricus (Totting) de Oyta († 1397 in Wien) überliefert sind. Einem Hinweis auf einen zweiten Textzeugen folgend, habe ich inzwischen auch die Mainzer Hs I 613 (=M) untersucht, was wertvolle Ergebnisse zutage gebracht hat: Dieser Codex enthält eine Fülle von 26 bzw. 28 Texten hauptsächlich aus den Gebieten der Philosophie (Nr. 1–12 u. 26), der Astronomie bzw. Komputistik (Nr. 13–17) und der Medizin (Nr. 18–22); nur der Block Nr. 23–25 ist anderen Inhalts (Grammatik, Kirchenrecht, Poesie). Die wichtigeren Ergebnisse schicke ich hier voraus, für Einzelheiten verweise ich auf die Anmerkungen zu den jeweiligen Texten in der folgenden Beschreibung.
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Muehlethaler, Vincent, Anette M. Kunig, Gregory Seedorf, Vivek Balasubramaniam, and Steven H. Abman. "Impaired VEGF and nitric oxide signaling after nitrofen exposure in rat fetal lung explants." American Journal of Physiology-Lung Cellular and Molecular Physiology 294, no. 1 (January 2008): L110—L120. http://dx.doi.org/10.1152/ajplung.00407.2007.
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We hypothesized that abnormal fetal lung growth in experimental congenital diaphragmatic hernia after maternal nitrofen exposure alters lung structure due to impaired VEGF signaling, which can be reversed with VEGF or nitric oxide (NO) treatment. Timed-pregnant Sprague-Dawley rats were treated with nitrofen on embryonic day 9 (E9), and fetal lungs were harvested for explant culture on E15. Explants were maintained in 3% O2for 3 days and were treated with NO gas or recombinant human VEGF protein for 3 days. To determine the effects of VEGF inhibition on lung structure, normal fetal lung explants were treated with SU-5416, a VEGF receptor inhibitor, with or without exogenous NO or VEGF. We found that nitrofen treatment impaired lung structure, as evidenced by decreased branching at day 0, but lung structure was not different from controls after 3 days in culture. Nitrofen reduced lung VEGF but not endothelial NO synthase protein level. Treatment with NO enhanced lung growth in control and nitrofen-exposed lungs; however, the response to NO in the nitrofen-treated lungs was reduced when compared with controls. VEGF treatment did not cause a further increase in lung complexity after nitrofen exposure. SU-5416 treatment altered lung structure, which improved with NO but not VEGF treatment. Both nitrofen and SU-5416 treatment increased apoptosis in the mesenchyme of fetal lung explants. We conclude that nitrofen exposure increased apoptosis, decreased lung growth and reduced VEGF expression, and that exogenous NO but not VEGF treatment enhances lung growth. Disruption of lung architecture after VEGF receptor blockade was similar to nitrofen-induced changes but was more responsive to NO.
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Sinapoy, Jumardin, Jamili Jamili, and Analuddin Analuddin. "Bioakumulasi Logam Nikel dan Pola Ordinasi Pada Gastropoda di Kawasan Mangrove Sekitar Areal Bekas Lahan Pertambangan Kabupaten Konawe Utara Sulawesi Tenggara." BioWallacea : Jurnal Penelitian Biologi (Journal of Biological Research) 7, no. 1 (May 5, 2020): 1078. http://dx.doi.org/10.33772/biowallacea.v7i1.11813.
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This study aims to determine the bioaccumulation of nickel metal and the spatial distribution pattern of gastropods in the area of the former nickel mining area in Tokowuta Village, Lasolo District, North Konawe Regency, Southeast Sulawesi. The method used is a combination of the path method and sample plot. The parameters observed in this study include nickel bioaccumulation in gastropods, density, frequency, diversity index, uniformity index, dominance index, dispersal pattern, and PCA ordinance pattern. The results showed that there were seven species in this region where the highest nickel bioaccumulation was found in the type of Nerita lineata (0.068 ppm) and the lowest in Terebralia sulcata (0.017 ppm). The highest density and frequency were found in Terebralia sulcata (54.66% and 25.53%) and the lowest in Telescopium telescopium (1.93% and 4.26%). In this region has a low diversity index (1.36), a uniformity index that is an unstable community (0.70), a low index of dominance (0.35), cluster pattern distribution (1.19). The results of the PCA ordinance pattern study showed the spatial distribution of gastropod dissimilarity factors in each observation plot formed three clusters. Cluster 1 consists of plots 2 and 6. Cluster 2 consists of plots 3, 5, and 10. Cluster 3 consists of plots 1, 4, 7, 8, 9, 11, and 12. The spatial distribution of gastropod habitat factors in each observation plot forms three clusters with different characteristics. Cluster 1 is characterized by soil nickel content. Cluster 2 by salinity. Cluster 3 with pH and water temperature. The spatial distribution of gastropod types based on habitat characteristics can form four clusters. Cluster 1 consists of Littorariascabra. Cluster 2 consists of Terebraliasulcata species. Cluster 3 with Telescopium telescopium and Littoraria melanostoma species. Cluster 4 with Cerithidea cingulata, Cerithidea quadrata, and Nerita lineata species. Keywords: Nickel Metal, Gastropoda, Ordination PatternABSTRAKPenelitian ini bertujuan untuk mengetahui mengetahui bioakumulasi logam nikel dan pola distribusi spasial gastropoda di kawasanareal bekas lahan tambang nikel di Desa Tokowuta Kecamatan Lasolo Kabupaten Konawe Utara Sulawesi Tenggara. Metode yang digunakan adalah kombinasi antara metode jalur dan petak contoh. Parameter yang diamati pada penelitian ini meliputi bioakumulasi nikel pada gastropoda, kepadatan, frekuensi, indeks keanekaragaman, indeks keseragaman, indeks dominansi, pola penyebaran dan pola ordinansi PCA. Hasil penelitian menunjukkan terdapat tujuh spesies pada kawasan ini dimana bioakumulasi nikel tertinggi terdapat pada jenis Nerita lineata (0,068 ppm) dan terendah padaTerebralia sulcata (0,017 ppm). Kepadatan dan frekuensi tertinggi terdapat pada jenis Terebralia sulcata (54,66% dan 25,53%) dan terendah padaTelescopium telescopium (1,93% dan 4,26%).Pada Kawasan ini memiliki indeks keanekaragaman yang rendah (1,36), indeks keseragaman yang Komunitas Labil(0,70), indeks dominansi yang rendah (0,35), pola penyebaranmengelompok (1,19). Hasil penelitian pola ordinansi PCA menunjukkan sebaran spasial faktor disimilaritas gastropoda pada setiap plot pengamatan membentuk tiga cluster.Cluster 1 terdiri dari plot 2 dan 6. Cluster 2 terdiri dari plot 3, 5 dan 10. Cluster 3 terdiri dari plot 1, 4, 7, 8, 9, 11 dan 12. Sebaran spasial faktor habitat gastropoda pada setiap plot pengamatan membentuk tiga cluster dengan karakteristik yang berbeda. Cluster 1 dicirikan kadar nikel tanah. Cluster 2 oleh salinitas. Cluster 3 dengan pH dan suhu perairan. Sebaran spasial jenis gastropoda berdasarkan karakteristik habitat dapat membentuk empat cluster. Cluster 1 terdiri dari Littoraria scabra. Cluster 2 terdiri dari Terebralia sulcata. Cluster 3 dengan jenis Telescopium telescopium dan Littoraria melanostoma. Cluster 4 dengan jenis Cerithidea cingulata, Cerithidea quadrata dan Nerita lineata
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Sutjipto, Rachmat Heryanto. "Karakteristik dan Lingkungan Pengendapan Batubara Formasi Tanjung di Daerah Batulicin, Kalimantan Selatan." Jurnal Geologi dan Sumberdaya Mineral 21, no. 3 (October 12, 2020): 157. http://dx.doi.org/10.33332/jgsm.geologi.v21i3.538.
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Hasil analisis petrografi organik batubara Formasi Tanjung di daerah Batulicin menunjukkan bahwa vitrinit lebih berkembang dalam percontoh batubara di bagian timur daerah penelitian (65,2-80,0%) daripada di bagian barat (50,6-54,6%). Kandungan maseral eksinit pada percontoh batubara di bagian barat (14,4-38,2%) relatif lebih besar daripada kandungan eksinit di bagian timur daerah penelitian (6,4-17,6%). Kandungan maseral inertinit pada percontoh batubara di bagian barat (6,6-22,2%) relatif lebih besar daripada kandungan inertinit di bagian timur (0,6-5,4%). Nilai reflektansi vitrinit rata-rata (Rv) di bagian timur (0,50-0,53%) lebih besar daripada bagian barat (0,48-0,49%), disebabkan oleh adanya terobosan batuan diorit dan telah mengalami pensesaran. Peringkat seluruh batubara tersebut adalah subbituminus B, berdasarkan klasifikasi ASTM. Lingkungan pengendapan percontoh batubara dari bagian barat dengan nilai TPI (0,19-0,68) dan GI (2,37-8.27), terendapkan dalam lingkungan limnic sampai dengan limno-telmatic atau dataran delta bawah, sedangkan percontoh batubara dari bagian timur dengan nilai TPI (0,38-5,03) dan GI (13,6-133,3) terendapkan pada lingkungan limno-telmatic sampai telmatic atau dalam lingkungan dataran delta bawah hingga atas. Kesemuanya dalam kondisi genang laut.Katakunci : batubara, maseral, Formasi Tanjung, Cekungan Asam-asam.
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Swart, Enno, Holger Gothe, Falk Hoffmann, Peter Ihle, Ingrid Schubert, Christoph Stallmann, and Stefanie March. "Sonderheft Methodische Aspekte der Sekundärdatenanalyse." Das Gesundheitswesen 82, S 01 (March 2020): S1—S3. http://dx.doi.org/10.1055/a-1083-5461.
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Die wissenschaftliche Nutzung von Sekundärdaten, nicht allein von solchen der gesetzlichen Krankenversicherung (GKV), hat sich in den vergangenen Jahren fest in der Versorgungsforschung etabliert. Das zeigen das Memorandum Methoden der Versorgungsforschung 1 und Grundlagenwerke der Sekundärdatenanalyse 2. Gleichwohl entwickelt sich eine hohe Dynamik in diesem Forschungszweig, einerseits durch die zahlreichen durch den Innovationsfonds des Gemeinsamen Bundesausschusses (G-BA) geförderten Projekte mit Nutzung von Sekundärdaten, andererseits durch die rasant zunehmenden wissenschaftlichen Studien mit einem individuellen Datenlinkage von Primär- und Sekundärdaten oder Sekundärdaten unterschiedlicher Dateneigner.