Academic literature on the topic 'Dioxins Metabolism'

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Journal articles on the topic "Dioxins Metabolism"

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Dobrzyński, Maciej, Jan P. Madej, Anna Leśków, Małgorzata Tarnowska, Jacek Majda, Monika Szopa, Andrzej Gamian, and Piotr Kuropka. "The Improvement of the Adaptation Process of Tocopherol and Acetylsalicylic Acid in Offspring of Mothers Exposed to TCDD." Animals 11, no. 12 (December 1, 2021): 3430. http://dx.doi.org/10.3390/ani11123430.

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Dioxins are chemical compounds that may cause an inflammatory reaction. During dioxin-induced inflammation, generated reactive oxygen species lead to morphological changes in various tissues and in biochemical parameters. The aim of this study was to demonstrate the changes in the livers of rats whose mothers were exposed to dioxins and the protective role of α-tocopherol and acetylsalicylic acid in liver inflammation. The study material consisted of Buffalo rats who were the offspring of females treated with dioxin, dioxin + α-tocopherol, or dioxin + acetylsalicylic acid. Livers and blood sam
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Keke Hu, Nigel J. Bunce. "METABOLISM OF POLYCHLORINATED DIBENZO-p-DIOXINS AND RELATED DIOXIN-LIKE COMPOUNDS." Journal of Toxicology and Environmental Health, Part B 2, no. 2 (March 1999): 183–210. http://dx.doi.org/10.1080/109374099281214.

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Patrizi, Barbara, and Mario Siciliani de Cumis. "TCDD Toxicity Mediated by Epigenetic Mechanisms." International Journal of Molecular Sciences 19, no. 12 (December 18, 2018): 4101. http://dx.doi.org/10.3390/ijms19124101.

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Dioxins are highly toxic and persistent halogenated organic pollutants belonging to two families i.e., Polychlorinated Dibenzo-p-Dioxins (PCDDs) and Polychlorinated Dibenzo Furans (PCDFs). They can cause cancer, reproductive and developmental issues, damage to the immune system, and can deeply interfere with the endocrine system. Dioxins toxicity is mediated by the Aryl-hydrocarbon Receptor (AhR) which mediates the cellular metabolic adaptation to these planar aromatic xenobiotics through the classical transcriptional regulation pathway, including AhR binding of ligand in the cytosol, transloc
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Colquhoun, David R., Erica M. Hartmann, and Rolf U. Halden. "Proteomic Profiling of the Dioxin-Degrading BacteriumSphingomonas wittichiiRW1." Journal of Biomedicine and Biotechnology 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/408690.

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Sphingomonas wittichiiRW1 is a bacterium of interest due to its ability to degrade polychlorinated dioxins, which represent priority pollutants in the USA and worldwide. Although its genome has been fully sequenced, many questions exist regarding changes in protein expression ofS. wittichiiRW1 in response to dioxin metabolism. We used difference gel electrophoresis (DIGE) and matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) to identify proteomic changes induced by growth on dibenzofuran, a surrogate for dioxin, as compared to acetate. Approximately 10% of the entire put
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Chernyak, Yury I., Alla P. Merinova, Andrey A. Shelepchikov, Sergey I. Kolesnikov, and Jean A. Grassman. "Impact of dioxins on antipyrine metabolism in firefighters." Toxicology Letters 250-251 (May 2016): 35–41. http://dx.doi.org/10.1016/j.toxlet.2016.04.006.

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Swigonska, Sylwia, Tomasz Molcan, Anna Nynca, and Renata E. Ciereszko. "The involvement of CYP1A2 in biodegradation of dioxins in pigs." PLOS ONE 17, no. 5 (May 26, 2022): e0267162. http://dx.doi.org/10.1371/journal.pone.0267162.

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2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is one of the most harmful chemicals showing resistance to biodegradation. The majority of TCDD effects is mediated by the aryl hydrocarbon receptor (AhR) pathway. TCDD binding to AhR results in the activation of cytochrome P450 enzymes (CYP1A1, CYP1A2, CYP1B1) involved in dioxin biodegradation. The goal of the study was to explore the potential role of CYP1A2 in the metabolism of TCDD. We investigated a molecular structure of CYP1A2 and the binding selectivity and affinity between the pig CYP1A2 and: 1/ DiCDD or TCDD (dioxins differing in toxicity an
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Galimov, Sh N., A. Z. Abdullina, R. S. Kidrasova, and E. F. Galimova. "Level of dioxins and glutathione system status in semen of male patients with infertility." Kazan medical journal 94, no. 5 (October 15, 2013): 658–61. http://dx.doi.org/10.17816/kmj1913.

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Aim. To evaluate of contamination of ejaculate by polychlorinated Dibenzo-p-dioxins/furans and to analyze the glutathione system status in males with infertility. Methods. 168 infertile and 49 fertile men were examined. Semen analysis was made in accordance with the World Health Organization protocol. The semen levels of persistent organic pollutants (dioxins and furans) was determined by a combination of high-performance capillary gas chromatography and high-resolution mass spectrometry, glutathione-depended enzymes activity - by enzyme-linked immunosorbent assay. Results. It is found that th
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Hu, Keke, and Nigel J. Bunce. "Metabolism of polychlorinated dibenzo-p-dioxins by rat liver microsomes." Journal of Biochemical and Molecular Toxicology 13, no. 6 (1999): 307–15. http://dx.doi.org/10.1002/(sici)1099-0461(1999)13:6<307::aid-jbt4>3.0.co;2-p.

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Bock, Karl Walter. "Human and rodent aryl hydrocarbon receptor (AHR): from mediator of dioxin toxicity to physiologic AHR functions and therapeutic options." Biological Chemistry 398, no. 4 (April 1, 2017): 455–64. http://dx.doi.org/10.1515/hsz-2016-0303.

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Abstract Metabolism of aryl hydrocarbons and toxicity of dioxins led to the discovery of the aryl hydrocarbon receptor (AHR). Tremendous advances have been made on multiplicity of AHR signaling and identification of endogenous ligands including the tryptophan metabolites FICZ and kynurenine. However, human AHR functions are still poorly understood due to marked species differences as well as cell-type- and cell context-dependent AHR functions. Observations in dioxin-poisoned individuals may provide hints to physiologic AHR functions in humans. Based on these observations three human AHR functi
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Molcan, Tomasz, Sylwia Swigonska, Anna Nynca, Agnieszka Sadowska, Monika Ruszkowska, Karina Orlowska, and Renata E. Ciereszko. "Is CYP1B1 involved in the metabolism of dioxins in the pig?" Biochimica et Biophysica Acta (BBA) - General Subjects 1863, no. 2 (February 2019): 291–303. http://dx.doi.org/10.1016/j.bbagen.2018.09.024.

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Dissertations / Theses on the topic "Dioxins Metabolism"

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Furness, Sebastian George Barton. "Novel mechanisms for activation of the dioxin (Aryl-hydrocarbon) receptor /." Title page, table of contents and summary only, 2003. http://web4.library.adelaide.edu.au/theses/09PH/09phf988.pdf.

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Högberg, Pi. "Disruption of vitamin A metabolism by dioxin /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-608-1/.

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Shinkyo, Raku. "Structure-function analysis of mammalian cytochromes P450 involved in metabolism of dioxins." Kyoto University, 2006. http://hdl.handle.net/2433/144094.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第12357号<br>農博第1538号<br>新制||農||923(附属図書館)<br>学位論文||H18||N4115(農学部図書室)<br>24193<br>UT51-2006-J349<br>京都大学大学院農学研究科食品生物科学専攻<br>(主査)教授 井上 國世, 教授 吉川 正明, 教授 村田 幸作<br>学位規則第4条第1項該当
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Hu, Keke. "Structure-activity relationships for the metabolism of polychlorinated dibenzo-p-dioxins and related compounds." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ35799.pdf.

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Murtomaa-Hautala, M. (Mari). "Species-specific effects of dioxin exposure on xenobiotic metabolism and hard tissue in voles." Doctoral thesis, Oulun yliopisto, 2012. http://urn.fi/urn:isbn:9789514297830.

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Abstract The evaluation of the effects and levels of contaminants in wildlife is an essential part of assessing risks for chemical exposure in the environment. Although the circumstances are not as controlled as in laboratory, wildlife studies offer the concept of environmental exposure in its entirety, with all the natural variation. In the present study, two wild vole species, bank vole (Myodes glareolus) and field vole (Microtus agrestis), were used in assessing environmental levels of dioxins. The effects of dioxin exposure on tooth and bone development were studied in order to determine w
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Labaronne, Emmanuel. "Impacts métaboliques d'un mélange faiblement dosé de polluants alimentaires dans un modèle murin : effets dépendants de l'âge, du sexe et du contexte nutritionnel." Thesis, Lyon, 2016. http://www.theses.fr/2016LYSE1204/document.

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Plusieurs travaux suggèrent l'implication des polluants de l'environnement dans l'épidémie d'obésité et l'incidence du diabète. Cependant, l'impact cumulé de cette myriade de polluants auxquels l'homme est exposé à faibles doses pendant toute sa vie n'a pas été totalement appréhendé.Au laboratoire, nous utilisons un modèle souris d'exposition chronique (toute la vie) à un mélange de polluants (TCDD, PCB153, DEHP et BPA) via leur ajout à une alimentation obésogène ou standard. Les doses des polluants sont ajustées de sorte à ce que l'exposition soit de l'ordre de la Dose Journalière Tolérable,
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Arnoldsson, Kristina. "Polybrominated dibenzo-p-dioxins : Natural formation mechanisms and biota retention, maternal transfer, and effects." Doctoral thesis, Umeå universitet, Kemiska institutionen, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-50887.

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Polybrominated dibenzo-p-dioxins (PBDD) and dibenzofurans (PBDF) are a group of compounds of emerging interest as potential environmental stressors. Their structures as well as toxic responses are similar to the highly characterized toxicants polychlorinated dibenzo-p-dioxins. High levels of PBDDs have been found in algae, shellfish, and fish, also from remote areas in theBaltic Sea. This thesis presents studies on PBDD behavior in fish and offspring, and natural formation of PBDDs from naturally abundant phenolic precursors. The uptake, elimination, and maternal transfer of mono- to tetraBDD/
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Rosenzweig, Ella. "Exploring the role and the function of Aryl Hydrocarbon Receptor (AhR) and Aryl Hydrocarbon Nuclear Translocator (ARNT) in T cells." Thesis, University of Dundee, 2012. https://discovery.dundee.ac.uk/en/studentTheses/1d8657f4-b7b1-4508-a93f-76f21fa8d605.

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The Aryl Hydrocarbon Receptor (AhR) and the Aryl Hydrocarbon Nuclear Translocator (ARNT) play a role in mediating transcriptional responses to environmental pollutants, including the highly toxic compound 2,3,7,8-tetrachlorodibenzo -p-dioxin (TCDD) but also endogenous physiological ligands. More recent studies have also indicated that the AhR plays a role in the immune system notably in effector Th17 cells where it seems to be critical for the production of the IL-22 cytokine. It is known that AhR ligands such as dioxins can suppress CD8 T cell mediated antiviral immune responses but it is not
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Leblanc, Alix. "Effets d’un mélange de polluants organiques persistants sur le métabolisme hépatique." Thesis, Paris 5, 2014. http://www.theses.fr/2014PA05P629/document.

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Des études épidémiologiques ont montré que l’exposition à certains xénobiotiques est associée à une augmentation de la prévalence des maladies métaboliques. L’Homme est exposé à des mélanges de xénobiotiques de manière chronique et inévitable. Nous avons étudié les effets de l’interaction de deux xénobiotiques sur le métabolisme du foie, organe majeur de détoxification de l’organisme. Nous avons choisi deux perturbateurs endocriniens et polluants organiques persistants, qui activent des voies de signalisation différentes: la 2, 3, 7, 8 tétrachlorodibenzo-p-dioxine (TCDD), agissant via le récep
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Gadupudi, Gopi Srinivas. "PCB126-induced metabolic disruption: effects on liver metabolism and adipocyte development." Diss., University of Iowa, 2016. https://ir.uiowa.edu/etd/2208.

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Recently, persistent organic pollutants such as polychlorinated biphenyls (PCBs) were classified as “metabolic disruptors” for their suspected roles is altering metabolic and energy homeostasis through bioaccumulation in liver and adipose tissues. Among PCBs, a specific congener, 3,3',4,4',5-pentachlorobiphenyl (PCB126), is a potent arylhydrocarbon receptor (AhR) agonist and elicits toxicity similar to the classic dioxin, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). PCB126 levels found in human blood are particularly associated with diabetes and nonalcoholic fatty liver disease (NAFLD) in human
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Books on the topic "Dioxins Metabolism"

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Pohjanvirta, Raimo. The AH receptor in biology and toxicology. Hoboken, N.J: Wiley, 2011.

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NATO Advanced Study Institute on Carbon Dioxide: Chemical and Biochemical Uses as a Source of Carbon (1986 Pugnochiuso, Italy). Carbon dioxide as a source of carbon: Biochemical and chemical uses. Dordrecht: D. Reidel Pub. Co., 1987.

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The slender thread: Web of life, the story of carbon dioxide. Corpus Christi: Helix Press, 1985.

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McKinney, Aubrey R. The slender thread: Web of life, the story of carbon dioxide. Corpus Christi, Tex: Helix Press, 1995.

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Thoene, Barbara. Untersuchungen zur Aufnahme und Metabolisierung atmosphärischen Stickstoffdioxyds in oberindischen Organen der Fichte (Picea abies (L.) Karst.). Frankfurt/M: Wissenschafts-Verlag W. Maraun, 1991.

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W, Ludden Paul, Burris John E, and Burris Robert H. 1914-, eds. Nitrogen fixation and CO₂ metabolism: Proceedings of the Fourteenth Steenbock Symposium held 17-22 June 1984 at the University of Wisconsin--Madison, Madison, Wisconsin, U.S.A. New York: Elsevier, 1985.

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Ludden, P. W., and J. E. Burris. Nitrogen Fixation and Carbon Dioxide Metabolism. Elsevier, 1985.

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Nahas, G. Carbon Dioxide and Metabolic Regulations. Springer, 2011.

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Pohjanvirta, Raimo. AH Receptor in Biology and Toxicology. Wiley & Sons, Incorporated, John, 2011.

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Pohjanvirta, Raimo. AH Receptor in Biology and Toxicology. Wiley & Sons, Incorporated, John, 2011.

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Book chapters on the topic "Dioxins Metabolism"

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Jaiswal, Prashant Kumar, and Jyotsana Gupta. "Metabolism of Dioxins and Dioxins-Like Compound, Its Regulation and Toxicological Pathways." In Environmental Microbiology and Biotechnology, 293–308. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-7493-1_14.

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Miller, Alexander L. "Carbon Dioxide Narcosis." In Cerebral Energy Metabolism and Metabolic Encephalopathy, 143–62. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-1209-3_6.

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Ranimol, G., C. B. Devipriya, and Swetha Sunkar. "Docking and Molecular Dynamics Simulation Studies for the Evaluation of Laccase Mediated Biodegradation of Triclosan." In Proceedings of the Conference BioSangam 2022: Emerging Trends in Biotechnology (BIOSANGAM 2022), 205–13. Dordrecht: Atlantis Press International BV, 2022. http://dx.doi.org/10.2991/978-94-6463-020-6_20.

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AbstractTriclosan (TCA) is an antibacterial and antimicrobial compound that is incorporated into toothpaste, soap, and liquid dishwasher. Continuous TCA exposure may contribute to the emergence of antibiotic-resistant bacteria in the microbiome. Triclosan also reacts to form dioxins, which bioaccumulate and are toxic to aquatic organisms, impedes the thyroid hormone metabolism of the human body. Laccases are multi copper-containing enzymes that can degrade the aromatic compounds and thus reduce their toxicity. To effectively degrade the compound, it is essential to understand the molecular function of the enzyme. Hence, a molecular docking study of laccase enzymes with Triclosan was done. The Tramates versicolor laccase structure was retrieved from PDB and ligand structure was taken from Pubchem. The binding mode and interaction of TCA and laccase were studied using Auto dock Vina software and the stability of the docked complex had been explored via Molecular Dynamics (MD) simulation study using Schrodinger Desmonde. The binding affinity score was found to be −6.5kcal/mol. The majority of the residues in RMSF were within the 2.5Å limit. The radius of gyration remained within the range from 21.7 to 22.1Å for Laccase – TCA complex throughout the 50 ns simulation. MD simulation results show that the enzyme complex remains stable all through the catalytic action.
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Karol, Paul J. "Respiration and Metabolism." In The Legacy of Carbon Dioxide, 153–64. Boca Raton : CRC Press, Taylor & Francis Group, 2019.: CRC Press, 2019. http://dx.doi.org/10.1201/9780429200649-15.

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Alscher, Ruth, Michael Franz, and C. W. Jeske. "Sulfur Dioxide and Chloroplast Metabolism." In Phytochemical Effects of Environmental Compounds, 1–28. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1931-3_1.

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Sheoran, I. S., and Randhir Singh. "Carbon Dioxide Metabolism in Photosynthesis." In Concepts in Photobiology, 430–73. Dordrecht: Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-011-4832-0_14.

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Kondo, Noriaki. "Uptake, Metabolism, and Detoxification of Sulfur Dioxide." In Air Pollution and Plant Biotechnology, 179–99. Tokyo: Springer Japan, 2002. http://dx.doi.org/10.1007/978-4-431-68388-9_9.

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Fuchs, Georg. "One-Carbon Metabolism of Anaerobic Bacteria: Challenge for Chemistry." In Enzymatic and Model Carboxylation and Reduction Reactions for Carbon Dioxide Utilization, 293–300. Dordrecht: Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-0663-1_17.

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Yoneyama, Tadakatsu, Hak Y. Kim, Hiromichi Morikawa, and Hari S. Srivastava. "Metabolism and Detoxification of Nitrogen Dioxide and Ammonia in Plants." In Air Pollution and Plant Biotechnology, 221–34. Tokyo: Springer Japan, 2002. http://dx.doi.org/10.1007/978-4-431-68388-9_11.

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Li, Xin, Golam Jalal Ahammed, Lan Zhang, Peng Yan, Liping Zhang, and Wen-Yan Han. "Elevated Carbon Dioxide-Induced Perturbations in Metabolism of Tea Plants." In Stress Physiology of Tea in the Face of Climate Change, 135–55. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-2140-5_7.

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Conference papers on the topic "Dioxins Metabolism"

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Gogol, Elina V., Guzel I. Gumerova, and Olga S. Egrova. "Approaches to Assessment and Hazard Identification of Dioxins." In Environmental Engineering. VGTU Technika, 2017. http://dx.doi.org/10.3846/enviro.2017.021.

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In the Russian practice in the framework of environmental regulation sanitary measurements to assess the toxicity of the objects of the environment, which are based on the determination of standardized components concentrations and comparing them with the limit value, are widely used. But this approach doesn’t allow assessing the degree of biological hazards for organisms. The biotesting method has been considered for assessing the safety of dioxin-like compounds. Dioxins can be formed out of control in the environment. Ultraviolet radiation accelerates the formation of dioxins, as it enhances
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Habran, S., Th Desaive, Ph Morimont, B. Lambermont, and P. C. Dauby. "Importance of metabolism variations in a model of extracorporeal carbon dioxide removal." In 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2016. http://dx.doi.org/10.1109/embc.2016.7591669.

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Albuquerque-Neto, Cyro, and Jurandir Itizo Yanagihara. "A Passive Model of the Heat, Oxygen and Carbon Dioxide Transport in the Human Body." In ASME 2009 International Mechanical Engineering Congress and Exposition. ASMEDC, 2009. http://dx.doi.org/10.1115/imece2009-11104.

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The aim of this work is the development of a mathematical model which integrates a model of the human respiratory system and a model of the human thermal system. Both models were previously developed at the same laboratory, based on classical works. The human body was divided in 15 segments: head, neck, trunk, arms, forearms, hands, thighs, legs and feet. Those segments have the form of a cylinder (circular cross-section) or a parallelogram (hands and feet) with the following tissue layers: muscle, fat, skin, bone, brain, lung, heart and viscera. Two different geometries are used to model the
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Xia, Chunguang, and Nicholas Fang. "Enhanced Mass Transport Through Permeable Polymer Microcirculatory Networks." In ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-15408.

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One of the obstacles of culturing functioning vital tissues in vitro is to obtain a substantial biomass at a physiological cell density (&amp;gt;108cells/cm3). At this high density, the diffusion length of metabolites is limited to ~100um. As a matter of fact, in real tissue, almost all the cells are located within 100um distance from the capillaries [1]. Studies [2, 3] also confirmed that the cells in the artificial tissue cannot be properly cultured when they are further than 400um from the external nutrient source. Therefore, to culture three dimensional artificial tissue with substantial b
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Ley, Obdulia, and Yildiz Bayazitoglu. "Effect of Physiological Parameters on the Temperature Distribution of a Layered Head Model." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-32044.

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Brain temperature control is important in clinical therapy, because moderate temperature reduction of brain temperature increases the survival rate after head trauma. A factor that affects the brain temperature distribution is the cerebral blood flow, which is controlled by autoregulatory mechanisms. To improve the existing thermal models of brain, we incorporate the effect of the temperature over the metabolic heat generation, and the regulatory processes that control the cerebral blood perfusion and depend on physiological parameters like, the mean arterial blood pressure, the partial pressu
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Ito, Miu, and Yuichi Sugai. "Study on Enhanced Oil Recovery Using Microorganism Generating Foam in Presence of Nanobubbles." In SPE/IATMI Asia Pacific Oil & Gas Conference and Exhibition. SPE, 2021. http://dx.doi.org/10.2118/205671-ms.

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Abstract Both high cost and environmental load of surfactant are issues to be solved in foam EOR. Moreover, it is difficult to control the injection of surfactant and gas so that the foam is generated in only high permeable zones selectively in oil reservoir. The authors have found a foam generating microorganism and hit upon an idea of the microbial foam EOR which makes the microorganism do generating foam in oil reservoir. The mechanism of the microbial foam generation and culture condition suitable for the foam generation were studied in this study. A species of Pseudomonas aeruginosa was u
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Zarin, A. S., Arup Lal Chakraborty, and Abhishek Upadhyay. "Detecting metabolic carbon dioxide using a tunable laser for non-invasive monitoring of growth of bacterial pathogens." In 2017 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC). IEEE, 2017. http://dx.doi.org/10.1109/cleoe-eqec.2017.8087202.

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Jacobs, A., and W. Everett. "A Fully Operational Pilot Plant for Eliminating Radioactive Oils Mixed With Chlorinated Solvents." In ASME 2011 14th International Conference on Environmental Remediation and Radioactive Waste Management. ASMEDC, 2011. http://dx.doi.org/10.1115/icem2011-59044.

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Disposal of organic liquid waste has become an increasing issue for many nuclear sites. Existing disposal solutions such as incineration or super critical water techniques are not compatible with wastes containing chlorinated solvents or fluorine owing to corrosion problems. As an example several hundred cubic meters of lubricating oils mixed with trichloroethylene (TCE) or perchloroethylene (PCE) are stockpiled on several French nuclear sites. For several years Dewdrops has been developing an original combination of mineralization processes for waste oils and solvents particularly well suited
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Pickering, Karen D., Eugene K. Ungar, Leticia M. Vega, and Melissa L. Campbell. "Fluid Mechanics and Biological Interaction in a Tubular Nitrifier Designed for Use in Space." In ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-1420.

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Abstract Biological processes are currently being investigated for use in spacecraft wastewater treatment. In a biological wastewater processor, microorganisms are used to degrade organic and inorganic contaminants to carbon dioxide, water, and other metabolic products. One step in the process is nitrification, in which ammonium ions in the wastewater stream are converted to nitrate ions. Traditional reactor designs for nitrification, which include continuously stirred tank reactors and trickling filters, are unsuitable for use on spacecraft due to their reliance on gravity for aeration. A tub
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Hossain, Md Shahadat, Shriram B. Pillapakkam, Bhavin Dalal, Ian S. Fischer, Nadine Aubry, and Pushpendra Singh. "Modeling of Blood Flow in the Human Brain." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-64525.

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Under normal conditions, Cerebral Blood Flow (CBF) is related to the metabolism of the cerebral tissue. Three factors that contribute significantly to the regulation of CBF include the carbon dioxide and hydrogen ion concentration, oxygen deficiency and the level of cerebral activity. These regulatory mechanisms ensure a constant CBF of 50 to 55 ml per 100g of brain per minute for mean arterial blood pressure between 60–180 mm Hg. Under severe conditions when the autoregulatory mechanism fails to compensate, sympathetic nervous system constricts the large and intermediate sized arteries and pr
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Reports on the topic "Dioxins Metabolism"

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Eck, William S. Studies on Metabolism of 1,4-Dioxane. Fort Belvoir, VA: Defense Technical Information Center, March 2010. http://dx.doi.org/10.21236/ada528633.

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Johnson, K. M. Single-operator multiparameter metabolic analyzer (SOMMA) for total carbon dioxide (C{sub T}) with coulometric detection. Operator`s manual. Office of Scientific and Technical Information (OSTI), January 1992. http://dx.doi.org/10.2172/10194787.

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Wackett, Lawrence, Raphi Mandelbaum, and Michael Sadowsky. Bacterial Mineralization of Atrazine as a Model for Herbicide Biodegradation: Molecular and Applied Aspects. United States Department of Agriculture, January 1999. http://dx.doi.org/10.32747/1999.7695835.bard.

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Atrazine is a broadly used herbicide in agriculture and it was used here as a model to study the biodegradation of herbicides. The bacterium Pseudomonas sp. ADP metabolizes atrazine to carbon dioxide and ammonia and chloride. The genes encoding atrazine catabolism to cyanuric acid were cloned and expressed in Escherichia coli. The genes were designated atzA, atzB and atzC. Each gene was sequenced. The enzyme activities were characterized. AtzA is atrazine chlorohydrolase which takes atrazine to hydroxyatrizine. AtzB is hydroxyatrazine N-ethylaminohydrolase which produces N-isopropylammelide an
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