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1

Singh, Aradhana, Raj K. Singh, and Vani Aditya. "Evaluation of “Diabetes in Pregnancy Study Group of India” (DIPSI) Criterion as a Diagnostic Test for Gestational Diabetes Mellitus." International Journal of Health Sciences and Research 11, no. 6 (June 10, 2021): 1–5. http://dx.doi.org/10.52403/ijhsr.20210601.

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Introduction: In view of the alarmingly increasing incidence of Gestational Diabetes Mellitus (GDM), worldwide, as well as in India, a consensus to bring about standardization for diagnosis of GDM is needed. Internationally, the WHO 2013 criteria is being widely used, while (Diabetes In Pregnancy Study Group of India) DIPSI non fasting criteria is popularly used in India. There still remains many missed cases of GDM in India, which is a cause of concern. This study was done to compare the DIPSI non fasting, with WHO 2013 criteria for diagnosis of GDM. Methods: this cross-sectional study included 530 pregnant women, attending antenatal clinic of a tertiary care center, of North India, from Feb. 2018 to March 2019 and fulfilling inclusion criteria. All women attending antenatal clinic, during the study period, were subjected to capillary glucose evaluation, 2 hours after 75g oral glucose load, irrespective of the timing of last meal (DIPSI), as part of routine antenatal checkup. After 7 days, only those 530 women, who turned up in fasting state, and fulfilled inclusion criteria, were enrolled in the study and subjected to fasting 75g, oral glucose tolerance test (OGTT) (WHO 2013). Accuracy of DIPSI test was compared, to the fasting WHO 2013 criteria. Capillary glucose was measured using regular, well calibrated, point of care, “Optium Free Style” glucometer. Results: Out of 107 women diagnosed to have GDM by WHO 2013 criteria, only 89 were diagnosed by the DIPSI criteria. DIPSI had a low sensitivity (83.18%) when compared to the WHO 2013 criteria, Conclusion: This study showed that when non fasting DIPSI criteria was used as diagnostic criteria, 10.58% women with GDM, missed the diagnosis. Considering the adverse maternal and perinatal outcome of GDM, implication of missed diagnosis would be grave, especially in a developing country, like India. Hence, use of DIPSI criteria for diagnosing GDM should be reconsidered. Key words: GDM, DIPSI, OGTT, Diabetes in Pregnancy.
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2

Shrestha, Biloni, and L. Pokhrel. "Comparative study of DIPSI and WHO 2018 criteria for diagnosis of GDM." Nepal Medical College Journal 22, no. 1-2 (July 13, 2020): 13–17. http://dx.doi.org/10.3126/nmcj.v22i1-2.30023.

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Gestational Diabetes Mellitus (GDM) is an important public health problem. Prevalence has shown an increasing trend and varies based on diagnostic criteria used and the ethnic group studied. It is more common in Asia. Presently, there is no international consensus on the screening and diagnostic criteria for GDM. The Diabetes in Pregnancy Study Group of India (DIPSI) guidelines recommend the non-fasting 75g oral glucose tolerance test (OGTT) as a single-step screening and diagnostic test for GDM, is simple, easy and more feasible. The objective of this study was to compare whether the DIPSI criteria is equally sensitive to WHO 2018 criteria. This was a hospital based cross-sectional study done at Nepal Medical College Teaching Hospital, Kathmandu. Among 425 cases, 25 (5.88%) were diagnosed GDM, 6 (1.41%) were diagnosed only by DIPSI, 5 (1.18) only by WHO 2018 and 14 (3.29%) by both methods. The study showed that the sensitivity of DIPSI was 73.68% and specificity was 98.52%. The agreement between the DIPSI and WHO 2018 criteria ranged from 60% to 80% (Kappa value = 0.68). This study proves that DIPSI criteria is comparable to WHO 2018 criteria and can be adopted in our institution for the diagnosis of GDM as it is more feasible, easy and less expensive.
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Ruge, Trupti C., and Nisha Kanchana. "Prevalence of gestational diabetes mellitus using IADPSG and DIPSI criteria: a cross-sectional study." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 6 (May 27, 2020): 2408. http://dx.doi.org/10.18203/2320-1770.ijrcog20202320.

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Background: Considering the magnitude of adverse pregnancy outcomes related to gestational diabetes, the present study was undertaken to find out the prevalence of gestational diabetes mellitus using the international association of diabetes in pregnancy study groups criteria (IADPSG) and diabetes in pregnancy study group India (DIPSI) criteria to ascertain whether the present practice of diagnosing GDM by the guidelines recommended by DIPSI 21 based on WHO criterion of 2-h PG ≥140 mg/dL can still be followed in this study settings or adopt IADPSG recommendation.Methods: This study was done at Antenatal Clinic, department of obstetrics and gynecology, KLES Dr Prabhakar Kore Hospital, Belgaum from January 2013 to December 2013. A total of 225 pregnant women between 24 to 28 weeks gestations were studied. Diagnosis and the prevalence of GDM were assessed by applying both DIPSI and IADPSG criteria.Results: Most of the women (58.11%) were between 22 to 25 years and the mean age was 23.78±3.38 years. Based on the IADPSG criteria, the prevalence of GDM was 19.11% and by applying DIPSI criteria, prevalence of GDM was 16.89%. The difference in diagnostic capability between IADPSG and DIPSI was found to be 2.8% and the kappa statistics showed good strength of agreement between the two tests (p>0.302; Kappa=0.774).Conclusions: It was concluded that, the diagnosis GDM based on DIPSI is as effective as IADPSG criteria. Further, in resource poor countries like India, DIPSI procedure would be used with an advantage of being less costly and without compromising the clinical equipoise.
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Sinha, Somya, and Niranjan M. Mayadeo. "Comparison of maternal and fetal outcomes in gestational diabetes mellitus diagnosed either by oral glucose tolerance test or diabetes in pregnancy study group India." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 10 (September 23, 2017): 4526. http://dx.doi.org/10.18203/2320-1770.ijrcog20174436.

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Background: The optimal strategy for screening and diagnosis of Gestational Diabetes Mellitus (GDM) is still controversial and elusive. There is possibility of difference in maternal and fetal outcome depending on the diagnostic method used. This study throws light on the efficacy of two screening tests “Oral Glucose Tolerance Test’’ and “Diabetes in Pregnancy Study Group India” and to know maternal and fetal outcome in pregnancy complicated by GDM in Indian setting.Methods: Depending on the diagnostic method used 100 GDM patients were divided in 2 groups: 1. OGTT, 2. DIPSI. Maternal outcomes were measured in terms of pregnancy induced hypertension, polyhydramnios, preterm labour, genital tract injury and methods of termination of pregnancy, gestational age at delivery. Congenital malformation, macrosomia, hypoglycemia, hyperbilirubinimia, respiratory distress, duration of NICU stay was studied in newborns.Results: 22% of DIPSI group and 26% of OGTT group had PIH as comorbidity. Preterm delivery was noted in 22% of DIPSI group and 30% of OGTT group. 50% patients of both the groups underwent LSCS. No intrapartum complications were seen in 82% of patients. Malformations were noted in 18% of DIPSI group and 14% of OGTT group. In DIPSI group 14% of baby had macrosomia compared to 10% and in that of OGTT group.In neonates, hypoglycaemia, respiratory distress syndrome and hyperbilirubinemia seen in 46.8%, 31% and 42.6% respectively in DIPSI group compared to 50%, 45.5% and 47.7% respectively in OGTT group.Conclusions: No statistically significant difference was noted with respect to maternal and fetal outcomes between the two groups.
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Saxena, Rajiv Kumar, Noor Fathima Tameem Ansari, and Pallavi Singh. "Effectiveness of diabetes in pregnancy study group India diagnostic criterion in detecting gestational diabetes mellitus: a rural Bangalore study." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 2 (January 28, 2020): 601. http://dx.doi.org/10.18203/2320-1770.ijrcog20200344.

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Background: The oral glucose tolerance test (OGTT) is considered the current standard for diagnosis of gestational diabetes mellitus (GDM). International association of diabetes and pregnancy study groups (IADPSG) recommends OGTT, with fasting, one-hour and two-hour venous blood samples drawn after intake of 75g oral glucose. In the Indian context, diabetes in pregnancy study group in India (DIPSI) recommends glucose challenge test (GCT), where 75 g glucose is given irrespective of the fasting state, and a single venous sample is drawn after two-hour. Diagnosis of GDM is made, if any cut-off value is met or exceeded. This prospective study was conducted to compare the DIPSI and IADPSG criteria for diagnosis of GDM.Methods: Pregnant women between 24 to 28 weeks of gestation were subjected to non-fasting GCT. Capillary sample were also drawn simultaneously using Accu check active glucometer. These women were counselled to undergo a standard 75gram OGTT, within a week of recruitment.Results: According to IADPSG criteria, 17.6% (18/102) of our participants had GDM, as compared to 19.6% (20/102) by DIPSI criteria using venous samples, and 25.3% (25/99) by capillary sample method. Sensitivity and specificity of GCT using venous sample was 72.22% and 91.67%, and using capillary sample was 70.59% and 84.15% respectively. DIPSI criteria using venous samples wrongly labelled 8.3% women as GDM, and capillary samples wrongly labelled 15.9% women as GDM. More importantly DIPSI criteria using venous samples labelled 27.8% women as false-negative and capillary samples labelled 29.4% women as false-negative for GDM. Almost one quarter of women with GDM will be missed if DIPSI criteria is used as a universal screening modality.Conclusions: We suggest that the IADPSG criteria be used for diagnosis of GDM in antenatal women in India.
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Phulpagar, Aditi, Prasad Deshmukh, and Anurag Gunderia. "Screening for Gestational Diabetes by DIPSI Guidelines." International Journal of Biomedical Research 9, no. 3 (April 1, 2018): 121. http://dx.doi.org/10.7439/ijbr.v9i3.4724.

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Aim and Objectives: The present study was undertaken to find out the role and effectiveness of DIPSI guidelines as a replacement for other more time consuming and cost effective methods for detecting gestational diabetes mellitus (GDM) in the Indian population and to compare outcome between GDM and non GDM population.Methods: A total of 345 women were selected of low risk category between the gestational ages of 24 to 28 weeks and were subjected to screening for gestational diabetes by DIPSI guidelines. A 75mg oral glucose load was given irrespective of their last Meal timing followed by blood glucose estimation by glucose oxidase – peroxidase method. A report of ≥140mg/dl were labeled as GDM as per DIPSI guidelines.Results: Out of 345 subjects screened, 30 (8.7%) were positive for GDM. The false positives encountered with DIPSI were 0.57% (2/345) and another 2 cases (0.57%) were false negative by DIPSI criteria. The rate of LSCS and rate of macrosomia was significantly higher in GDM population (30% and 33.33% respectively) as compared to general population (4.4% and 2.5% respectively). In GDM group 23.3% (7) had Shoulder Dystocia compared with 0.6% (2) in the normal population. 10% were breech compared with only 0.2% in the general population with 1 IUFD requiring hysterotomy. The rates of CPD were also higher (3.3%) than the general population (1.5%). A total of 19 neonates required NICU admission of which 11 were IDM. 36.66% of IDM required NICU admission as compared to only 2.5% of the non diabetic population.Conclusions: DIPSI guidelines can use as a replacement for other more resource and time consuming and costly methods like ADA criteria for the detection of GDM in the low resource settings in developing countries.
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Desai, Grishma Girish, and Pundalik Sonawane. "Comparison of DIPSI guidelines versus conventional OGTT for diagnosis of gestational diabetes mellitus." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 8 (July 26, 2018): 3168. http://dx.doi.org/10.18203/2320-1770.ijrcog20183311.

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Background: Gestational Diabetes Mellitus (GDM) is defined as carbohydrate intolerance with recognition or onset during pregnancy is associated with a higher rate of maternal and fetal compromise. OGTT is the current gold standard for screening for GDM. It is a two-step test which requires the pregnant woman to be in a fasting state for a long duration. DIPSI is a one-step procedure for diagnosing GDM does not require patients in a fasting state and is a simple, economical and feasible alternate in Indian scenario. The aim of this study is to compare DIPSI criteria-based test with conventional OGTT for diagnosis of GDM.Methods: A hospital-based screening study was conducted at Department of Obstetrics and Gynecology, K J Somaiya Medical College and hospital, Mumbai for duration of May 2015 to June 2016. A total of 200 consecutive pregnant women in the second and third trimester of pregnancy registered at our antenatal clinic and satisfying the eligibility criteria were taken in the study after informed consent. Pregnant women with 2-h PG ≥ 7.8 mmol/L (DIPSI criterion) were diagnosed as GDM and rest were classified as normal glucose tolerant (NGT) women. One week later all of them were made to undergo the conventional 75 gm OGTT. Data was analyzed using statistical software SPSS ver. 21.Results: The sensitivity and specificity of DIPSI was 86.8% and 98.8% with PPV and NPV of 94.3% and 97.0% and overall diagnostic accuracy was 96.5%.Conclusions: The results of present study show that DIPSI is a simple, single, convenient, economical screening test for GDM and can be used as both diagnostic as well as screening test with good diagnostic efficacy.
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Khenwar, Deepti, Juhi Agarwal, and Sushruta Shriastava. "Screening of gestational diabetes mellitus using one-step versus two-step method: a comparative study." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 8 (July 23, 2020): 3372. http://dx.doi.org/10.18203/2320-1770.ijrcog20203325.

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Background: Gestational diabetes mellitus (GDM) is defined as carbohydrate intolerance of variable severity with onset or first recognition during the present pregnancy. It affects 7% of all pregnancies worldwide and in India it ranges from 6 to 9% in rural and 12 to 21% in urban area. The aim of this study was to compare the DIPSI criteria with the two-step method (Carpenter and Couston criteria.) and to study merits and demerits of one step and two step tests for GDM.Methods: A total 400 pregnant women of gestational age between 24-28 weeks attending antenatal clinic at this study tertiary care center were enrolled in this study. 200 pregnant women were enrolled in each of the study group (Group I OGTT and Group II DIPSI).Results: In Group I (OGTT) screening 47 (23.5%) were tested positive. In Group II cases, screening test results were found positive among 44 (22%). Out of 95 high-risk pregnant women 38 (40%) were positive for GDM by OGTT and 34 (35.78%) were positive by DIPSI. Out of 305 non high-risk pregnant women, 9 (2.95%) were positive for GDM by OGTT and 10 (3.27%) were positive by DIPSI.Conclusions: Present study concludes that DIPSI is the test which can predict GDM in population comparable to another test like OGTT. Also, India’s major population reside in rural areas, ANC are mostly conducted by ANM, therefore screening test should be easy to perform and interpret.
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Lakshmi Satyavathi, G. Anantha, and Chitti Sudha A. "Study on maternal and foetal outcome of pregnancy with positive glucose tolerance test by diabetes in pregnancy study group diagnostic criteria." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 9 (August 26, 2019): 3510. http://dx.doi.org/10.18203/2320-1770.ijrcog20193634.

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Background: Diabetes in Pregnancy Study group, India (DIPSI) diagnostic criteria is a single step method of screening and diagnosis of gestational Diabetes. Therefore, this prospective study was undertaken to ascertain the validity of DIPSI criteria to diagnose GDM based on pregnancy outcome in Indian population.Method: The present Hospital based prospective study was conducted at OBGY department, GSL Medical College and General Hospital, Rajahmundry during 2013 to 2015. Women who were attending OBGY OPD for Antenatal check-ups within 24-28 weeks of GA during the study period were included in the study. Each mother at 24-28 weeks of gestation irrespective of last meal timing, fasting / non fasting was given 75 gm glucose dissolved in a glass of 200 ml water to drink and after two hours venous blood was collected.Result: Out of 500 cases, 26 cases are diagnosed as having gestational diabetes by DIPSI criteria and 474 cases are Normal glucose tolerant. Maximum number 53.9% of cases diagnosed as GDM by DIPSI are of age >25 yrs (53.9%), primigravida (65.7%), BMI>25 (57.7%). In present study, family h/o diabetes is a risk factor for GDMConclusion: Our results suggest that a policy of universal screening for GDM should be adopted in all antenatal clinics and 75 gm OGTT has a high predictive value. This single step procedure is a simple economic and feasible method. It serves both for the purpose of screening and diagnosis at the same time.
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Shrivastava, Nikita, Kanchan Durugkar, Pallavi Viswanadh, and Himadri Bal. "The study of role of HbA1c as a predictor of gestational diabetes mellitus." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 11 (October 23, 2019): 4525. http://dx.doi.org/10.18203/2320-1770.ijrcog20194887.

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Background: India is the diabetic capital of the world and gestational diabetes mellitus contributes to a significant number of cases. Gestational diabetes mellitus is a common medical complication of pregnancy and may lead to serious consequences. Because of these reasons, it was felt that if there was a biomarker for predicting carbohydrate intolerance in pregnancy, it could help in earlier intervention and mitigate the consequences related to it. Hence, for this purpose, the role of HbA1c was studied as a predictor of gestational diabetes mellitus.Methods: This was a cross sectional study. Five hundred antenatal cases were considered for this study. All antenatal patients before 18 weeks of gestation attending antenatal clinic for the first time were selected and these patients were subjected to HbA1c followed by diabetes in pregnancy study group of India (DIPSI) test between 24-28 weeks and the results were analyzed to find any correlation between the two.Results: The main objective of the present study was to find whether HbA1c can be used as a predictor of gestational diabetes mellitus. In this study out of 500 women screened, 60 women turned out to have gestational diabetes mellitus. When comparing DIPSI positivity with various levels of HbA1c, it was found that maximum number of DIPSI positive patients (93.33%), had raised HbA1c levels.Conclusions: Maximum number of DIPSI positive cases had HbA1c level between 5.5 to 6 and this association was found to be statistically significant and a positive correlation was established between the two.
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Srinivasan, Swathy, and Rani P. Reddi. "Comparative study of DIPSI and IADPSG criteria for diagnosis of GDM." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 3 (February 27, 2018): 932. http://dx.doi.org/10.18203/2320-1770.ijrcog20180869.

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GDM is defined as any degree of glucose intolerance with onset or first recognition during pregnancy. The prevalence of GDM varies, widely based on the diagnostic criteria used and the ethnic group studied. It is associated with adverse maternal and perinatal outcome. Incidence of GDM in India is 1-14%. There are several screening and diagnostic tests for GDM. It is important to diagnose early and treat to prevent these complications. The present study was done to compare Diabetes in Pregnancy Study Group India (DIPSI) with International Association of the Diabetes and Pregnancy Study Groups (IADPSG) criteria for diagnosis of GDM and to assess the validity of these methods.Methods: It was a cross sectional study done in 144 pregnant women who fulfilled the inclusion criteria. They underwent non - fasting OGTT with 75 grams glucose which was given irrespective of the last meal. A venous blood sample was drawn two hours after glucose administration. They were advised to come two to three days later and repeated with 75 grams OGTT after an overnight fast of atleast 8 hours. Venous blood sample was drawn at fasting, one hour and two hours after load with 75 grams of glucose. Plasma glucose was measured by using an autoanalyzer by glucose - oxidase peroxidase (GOD - POD) technique.Results: The epidemiological parameters like Age, BMI, Parity and Gestational age did not have any difference between two groups. 17.4% was diagnosed by DIPSI criteria and 15.3% was diagnosed by IADPSG criteria and 6.9% was diagnosed by both. Sensitivity and specificity of DIPSI was 45% and87% and sensitivity and specificity of IADPSG was 40% and89% respectively. According to kappa statistics, the p-value is 0.000.Conclusions: In present study it was concluded that screening is very essential in all pregnant women due to high prevalence of GDM in India. By comparing these two criteria, sensitivity of DIPSI was found better than IADPSG criteria in diagnosing GDM. Though IADPSG is universally accepted for diagnosis, DIPSI has still got a place in low resource countries as it is easy, cost effective and non fasting test.
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Jadhav, Deepali S., and Uma N. Wankhede. "Comparative study of capillary blood glucose estimation by glucometer and venous plasma glucose estimation in women undergoing the one step Dipsi test (diabetes in pregnancy study group India) for screening and diagnosis of gestational diabetes mellitus." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 4 (March 30, 2017): 1488. http://dx.doi.org/10.18203/2320-1770.ijrcog20171415.

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Background: Gestational diabetes mellitus (GDM) is defined as carbohydrate intolerance of variable severity with onset or first recognition during pregnancy. The importance of GDM is that two generations are at risk of developing diabetes in the future. Aim was to study the merits and demerits of capillary blood glucose estimation by glucometer over venous plasma glucose estimation while performing DIPSI test.Methods: It was a hospital based clinical study. 1000 patients were enrolled between 24-28 weeks of gestation and DIPSI test was performed. Patient was instructed to come irrespective of fasting. 75 g glucose dissolved in 200-400 ml of water and patient was asked to drink in 5 minutes. Venous blood was drawn after 2 hours, capillary blood sugar also was measured at the same time by glucometer.Results: Sensitivity of capillary blood sugar (CBS) method in detecting GDM is 100% as compared to venous plasma glucose (VPG) and specificity is 99.46% as compared to VPG. Considering the agreement between two methods for diagnosis of GDM, equal sensitivity of both methods and small number of false positive cases detected by CBS method, due to almost equal specificity (99.46%), CBS method by glucometer can be recommended as an alternative to VPG method as a screening and diagnostic test for GDM.Conclusions: It is appropriate and feasible to offer capillary blood sugar sampling by DIPSI test for screening and diagnosis of GDM. The prevalence of GDM in our study is 8% by capillary blood sugar sampling and 7.5% by venous plasma glucose sampling according to DIPSI test.
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Khan, S., H. Bal, I. D. Khan, and D. Paul. "PREVALENCE OF GESTATIONAL DIABETES MELLITUS IN AN URBAN INDIAN COHORT USING DIABETES IN PREGNANCY STUDY GROUP IN INDIA (DIPSI) CRITERIA – VALIDATING ONE-STEP APPROACH." International Journal of Medicine and Medical Research 4, no. 2 (March 1, 2019): 13–19. http://dx.doi.org/10.11603/ijmmr.2413-6077.2018.2.9317.

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Background. India is the “World’s Diabetes capital”, with half the diabetic population being women. Early detection of glucose intolerance during pregnancy offers a timely opportunity for screening, management and prevention of gestational diabetes mellitus (GDM) and prevents fetal complications. Objective. The study assessed the prevalence of GDM in an Indian cohort using the Diabetes in Pregnancy Study group of India (DIPSI) criteria. Methods. 200 pregnant women underwent two-phase testing with non-fasting 75-gram glucose challenge under Diabetes in Pregnancy Study group of India (DIPSI) criteria at <20 weeks and between 24-28 weeks period of gestation. A 3-hour 100-gm oral glucose tolerance test (OGTT) was used for confirmation. Repeat testing was done for women negative during the first-phase. Results. Mean age was 24.26±3.75 years with 52.5% multigravidas. Mean Body Mass Index (BMI) was 20.7±3.07 kg/m2. The prevalence of GDM in study cohort was found to be 15.5% using the DIPSI criteria while the prevalence of GDM after 100 g OGTT was 13.0%. GDM was mostly seen to occur in women of 26-30-year age group. Statistically significant associations for age and GDM, and BMI and GDM were evidenced. Conclusions. Maternal age of ≥25 years should be adopted as a risk factor for the development of GDM. The DIPSI criteria offer a cost-effective and an evidence-based protocol for a single-step definitive glucose test for both screening and diagnosis of pregnant patients belonging to any socio-economic strata; furthering its implementation for public health obstetrics.
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L., Dwarakanath, Hema K. R., and Hemashree P. "One step procedure for screening and diagnosis of gestational diabetes mellitus by diabetes in pregnancy study group of India." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 8 (July 26, 2019): 3344. http://dx.doi.org/10.18203/2320-1770.ijrcog20193563.

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Background: In the Indian context, screening for Diabetes is essential in all pregnant women, as the Indian women have an eleven-fold increased risk of developing glucose intolerance during pregnancy. For this, we need a simple procedure which is economical and feasible. Hence this study was undertaken as a screening as it is acceptable, economical and feasible to perform. Aim of this study was to assess the feasibility of one step procedure for screening and diagnosis of Gestational Diabetes Mellitus by Diabetes in Pregnancy Study Group of India (DIPSI).aim of the study was to study the occurrence of Gestational Diabetes mellitus, Tumkur, to assess the sensitivity and specificity of glucose challenge test, to assess the need for universal screening and to study the maternal and perinatal outcomes in patient with Gestational Diabetes Mellitus.Method: Type of study was prospective study. this study included 200 pregnant women attending the antenatal OPD in Sri Siddhartha Medical College, Tumkur. Data collection was in a predesigned proforma. Pregnant women with 24-28 weeks of gestation were given 75 grams of oral glucose load, irrespective of their meal and venous blood sample drawn after 2 hours. If blood glucose value was ≥140mg/dl, the screening was considered as DIPSI positive. These patients underwent OGTT.Results: Incidence of GDM was found to be 3.5% in the patients studied. 40% of cases did not have risk factors, hencethere is a need for universal screening. DIPSI was positive in 10 cases, of which 7 were OGTT positive. Patients were managed with diet and insulin. The maternal and perinatal outcome of pregnancy was good.Conclusion: For universal screening, DIPSI performed irrespective of last meal timing with 75g glucose load is a patient friendly approach. This method recommended by WHO serves both as a one-step screening and diagnostic procedure & is easy to perform besides being economical.
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Gowda, Shashikala H., Tarigopula Swathi, and Rakshitha B. "Validation the sensitivity and specificity of diabetes in pregnancy study group of India recommended 75 g oral glucose challenge test by comparing with carpenter and couston 100 g oral glucose tolerence test." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, no. 9 (August 26, 2021): 3544. http://dx.doi.org/10.18203/2320-1770.ijrcog20213482.

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Background: Diabetes is one of the most common non communicable diseases globally. India is considered as the world diabetes capital. Women detected with gestational diabetes mellitus (GDM) have an increased incidence of developing diabetes; especially type 2 diabetes mellitus in the later life, and future development of obesity and diabetes in the offspring. So the aim of this study is to validate the sensitivity and specificity of diabetes in pregnancy study group of India (DIPSI) recommended 75 g oral glucose challenge test (OGCT) by comparing with carpenter and couston 100 g oral glucose tolerance test (OGTT) and to note the prevalence of gestational diabetes in antenatal population attending Kempegowda Institute of Medical Sciences (KIMS).Methods: All antenatal patients reporting to our hospital at or before 24 to 28 weeks period of gestation will be recruited for the study. Patients at random will be subjected to 75g glucose load according to DIPSI criteria and one week later to carpenter and couston 100 g OGTT. Blood glucose is estimated from venous blood using glucose oxidase and peroxidase (GOD-POD) method and patients diagnosed according to respective criteria.Results: Most of the patients were in age distribution of 20–25 years. Among 100 patients in study group 28 were diagnosed as GDM by DIPSI criteria. Among 100 patients, 12 patients were detected as GDM by carpenter and couston GTT, 19 patients had impaired glucose tolerance. The incidence of GDM in the antenatal population attending KIMS hospital between gestational ages of 24–28 weeks is 12%.Conclusions: DIPSI can be used as a diagnostic test for GDM as one step simple and easy procedure especially I low resource settings like India for improved pregnancy outcome.
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Brown, L. R., and B. C. Sanctuary. "Hetero-TOCSY experiments with WALTZ and DIPSI mixing sequences." Journal of Magnetic Resonance (1969) 91, no. 2 (February 1991): 413–21. http://dx.doi.org/10.1016/0022-2364(91)90207-a.

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Singh, Kirti, and Hafizur Rahman. "Frequency and management of gestational diabetes mellitus according to the new diabetes in pregnancy study group of India guidelines among Sikkimese women attending tertiary teaching hospital of East Sikkim." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 3 (February 27, 2020): 1181. http://dx.doi.org/10.18203/2320-1770.ijrcog20200896.

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Background: The screening of GDM is important as various pregnancy related complications are associated to it. With early screening and diagnosis, the complications associated with GDM can be reduced. Studies have shown various ethnic groups are at increasing risk of developing GDM with prevalence differing in different ethnicity. No data is available about frequency of GDM in different ethnic women of Sikkim. This study was performed to determine the frequency of GDM and its variation according to different demographic profiles of Sikkimese women.Methods: Pregnant women between 16-34 weeks of gestation, attending antenatal OPD were included for this study. All the patients were subjected to DIPSI recommended 75 gm oral glucose tolerance test. Diagnosis of impaired glucose tolerance was made when plasma glucose of ≥120-140 mg/dl and diagnosis of GDM was made when the plasma glucose of >140 mg/dl as per DIPSI guidelines.Results: A total of 202 consenting pregnant women during 16-34 weeks of pregnancy were evaluated with DIPSI recommended 75 g oral glucose tolerance test. Overall frequency of GDM was 11.9% among the Sikkimese women while 10.9% had impaired results in OGTT.Conclusions: Frequency of GDM was high (12%) in pregnant women attending tertiary hospital of Sikkim. This implies Sikkimese women should be universally screened for GDM. There was also high occurrence of GDM among Lepcha and Bhutia women which need further study to find out the contributing factors in these women.
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Pal, Aleeza, Bishan Dhiman, Rita Mittal, and Bhaskar J. Paul. "Prevalence of gestational diabetes mellitus and its feto-maternal outcome in Kamla Nehru state hospital for mother and child, IGMC, Shimla, India." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 11 (October 25, 2018): 4662. http://dx.doi.org/10.18203/2320-1770.ijrcog20184526.

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Background: Gestational Diabetes Mellitus (GDM) is defined as carbohydrate intolerance of variable severity with the onset or first recognition during pregnancy. It is a disease entity that adversely affects maternal as well as fetal outcome. DIPSI guideline having suggested one-time plasma glucose level has emerged as a simple, practical and cheap method to detect GDM. This study was done to evaluate the prevalence of gestational diabetes using Diabetes in Pregnancy Study Group India (DIPSI) criteria and further assess its feto maternal outcome in Kamla Nehru State Hospital for Mother and Child, IGMC, Shimla.Methods: This study was conducted in 500 patients between 24 and 28 weeks of gestation, attending the antenatal OPD. These patients were given 75g oral glucose irrespective of last meal and their plasma glucose was estimated at 2h. Patients with plasma glucose ≥140mg/dl were diagnosed as GDM and the rest as control or the non GDM group. The GDM patients were followed up and treated with medical nutrition therapy (MNT) and/or insulin therapy till delivery and maternal and fetal outcomes were then noted.Results: The prevalence of GDM in this study was 6%. Maternal and fetal complications were more in the GDM patients. Vaginal candidiasis and PROM were the common maternal complications, while hypoglycemia and hyperbilirubinemia were common in the fetuses.Conclusions: GDM adversely affects the mother as well as fetus. DIPSI guideline having suggested a single plasma glucose level test has emerged as a practical and economical method to detect GDM.
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Rucker, Steven P., and A. J. Shaka. "Broadband homonuclear cross polarization in 2D N.M.R. using DIPSI-2." Molecular Physics 68, no. 2 (October 10, 1989): 509–17. http://dx.doi.org/10.1080/00268978900102331.

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Magon, Navneet, and Monica Chauhan. "Diagnosing GDM: Role of Simple, Cost Effective, and Sensitive DIPSI Test." Journal of Obstetrics and Gynecology of India 64, no. 4 (July 23, 2014): 299–300. http://dx.doi.org/10.1007/s13224-014-0594-4.

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Sharma, Preeti, Neeta Chaudhary, and Suchitra Singh. "A study comparing non-gestational diabetes mellitus and gestational diabetes mellitus in antenatal patients in a tertiary care center." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 3 (February 27, 2020): 1201. http://dx.doi.org/10.18203/2320-1770.ijrcog20200900.

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Background: Gestational diabetes mellitus is defined as any glucose intolerance with the onset or first recognition during pregnancy. Objectives of this study were to diagnose cases of GDM by screening with DIPSI criteria at less than 28 weeks. And observation and comparison of maternal and perinatal outcome in women diagnosed of GDM in less than 20 weeks and at 24-28 weeks.Methods: This was the prospective analytical study conducted in the department of obstetrics and gynecology for one year in Muzaffarnagar medical college and Hospital. After history taking, clinical and obstetrics examination 1503 antenatal patients of less than 28 weeks were enrolled underwent screening with DIPSI criteria. Out of which 80 patients with abnormal OGTT of gestational age less than 20 weeks and 69 patients with abnormal OGTT of gestational age 24 -28 weeks.Results: In early diagnosed GDM group alive and healthy babies were slightly lower as compared with late diagnosed GDM group.Conclusions: The diagnosis of GDM gives us an opportunity in identifying individuals who will be benefitted by early therapeutic intervention with diet, exercise, and normalizing the weight to delay or prevent the onset of the disease.
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Soren, Mamata, Sudhanshu Sekhar Nath, Debananda Tudu, and Polaki Srilekha. "Screening for GDM in first trimester of pregnancy and its outcome." International Journal of Research in Medical Sciences 6, no. 2 (January 24, 2018): 603. http://dx.doi.org/10.18203/2320-6012.ijrms20180306.

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Background: GDM is associated with increased risk of complications for both mother and fetus both during pregnancy as well as in the postpartum period. Screening for GDM is important to improve short and long term maternal and fetal outcomes. The main purpose of this review is to provide an update on screening for GDM. As per DIPSI criteria women can be diagnosed to have GDM in the first trimester, if the 2hour 75gms OGTT IS 140-199 mg/dL. A prospective observational study with 300 cases was conducted for a period of 1year and 11months (December 2012-2014) in VIMSAR Burla, Sambalpur.Methods: Universal screening was applied by means of DIPSI. Analysis was done by means of t-test, Odd’s ratio, chi squire test. P<.05 was taken as significant.Results: In the present study, 25 cases were diagnosed as GDM with an incidence of 8.33%. Hypertensive disorders of pregnancy (HDP) was found significantly associated with GDM cases (p value 0.02). The mean birth weight in women with GDM (3.05±0.47Kg) was higher than in women with non-GDM (2.65±0.43 Kg). Overall the macrosomia (≥4Kg) rate was 0.67% with 8% in case of GDM mothers. Not a single case of congenital fetal anomaly was detected in the GDM group under our study 20% of the GDM group had their babies admitted to NICU as compared to 17.65% of the non-GDM group (p value 0.76).Conclusions: Women with GDM are at an increased risk for adverse obstetrics and perinatal outcomes. Due to high prevalence of GDM in India early universal screening is essential. Screening for glucose intolerance during the early weeks of pregnancy is beneficial as this policy would help in identifying undiagnosed diabetes prior to conception and to render appropriate care. Screening and diagnosis of GDM with a single test procedure of 75g 2hr PGBS in a non-fasting woman i.e. following DIPSI guidelines is found to be effective, simple, economical and feasible.
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Yadav, Manisha, and Gehanath Baral. "One step oral glucose challenge test as screening and diagnostic test for Gestational Diabetes Mellitus." Nepal Journal of Obstetrics and Gynaecology 14, no. 2 (December 31, 2019): 42–45. http://dx.doi.org/10.3126/njog.v14i2.28440.

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Aim: The Diabetes in Pregnancy Study Group of India (DIPSI, 2010) guidelines recommend the non-fasting 75-g oral glucose challenge test (OGCT) as a single-step screening and diagnostic test for gestational diabetes mellitus (GDM). The aim of this study was to assess the validity of DIPSI criteria by comparing with the World Health Organization (WHO) 1999 criteria of diagnosing GDM. Methods: This study was a hospital based prospective comparative study conducted among 282 pregnant women, of gestational age of 24-28 weeks attending antenatal OPD of Patan hospital. The OGCT was performed on them irrespective of fasting state and without any dietary preparation and they were again asked to come after 3 days of unrestricted carbohydrate diet in fasting state for WHO 2-hour oral glucose tolerance test (OGTT) with 75 gram of glucose load. The value of OGCT >140 mg/dl is diagnostic of GDM (DIPSI 2010). For the reliability of this test, it was compared with WHO 2-hour OGTT. Results: Among the study population, the mean age and BMI was 26.04±4.50 and 24.08±3.30 respectively. Out of 282 patients, 8 cases (2.83%) were found to have abnormal non-fasting 75-g OGCT and 4 cases (1.41%) had abnormal WHO 2-hour OGTT. Paired t test was employed to examine the difference of blood glucose level of the tests. There was statistically significant difference (p<0.001) between the tests. The Sensitivity, specificity, positive predictive value and negative predictive value of oral glucose challenge test was 25%, 97.48%, 12.5% and 98.90% respectively. The non- fasting 75-g OGCT was able to detect only 25% of the cases. Conclusions: Though the non-fasting 75-g OGCT test is cost effective and more compliant to pregnant women, the present report suggests that it cannot be used as a single step screening and diagnostic test because of its low sensitivity. However, it is an adequate alternative for screening test in resources limited areas.
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Geetha, Dr N., and Dr K. Gowri Sangeetha. "Comparison of Iadpsg And Dipsi Criteria for Diagnosis of Gestational Diabetes Mellitus." IOSR Journal of Dental and Medical Sciences 15, no. 09 (September 2016): 01–04. http://dx.doi.org/10.9790/0853-1509040104.

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Guin, Gita, and Ruchita Dadhich. "Gestational diabetes: know your risk by simple and single step criteria (DIPSI)." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 11 (October 28, 2017): 5107. http://dx.doi.org/10.18203/2320-1770.ijrcog20175034.

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Background: Gestational diabetes mellitus (GDM) has associations beyond the index pregnancy, identifying two generations at risk of future diabetes. Thus, detection of gestational diabetes mellitus becomes an important public health issue. This study aimed to estimate the prevalence of gestational diabetes mellitus by using simple and single step DIPSI criteria (Diabetes in pregnancy study group India) and risk factors associated with GDM.Methods: This cross-sectional study was carried out in 800 antenatal patients attending the antenatal clinic. These patients have given 82.5 gm mono-hydrous (75 gm anhydrous) oral glucose irrespective of the meals and their plasma glucose was estimated at 2 hr. Patients with plasma glucose value ≥140 mg/dl were diagnosed as GDM.Results: The present study estimated that the prevalence of GDM was 14.75% at their 1st visit. We found a positive association of GDM by age, BMI, hypertension and family history of diabetes. Older women had 4.5 times greater risk of GDM than younger women, obese women had 52 times higher risk of GDM than underweight women and hypertensive pregnant women had 4 times greater risk of GDM.Conclusions: It was realized that the test (DIPSI) could be easily performed in high volume hospitals comfortably and the patient were at ease as they were not fasting. Simple, cost effective tests, if made universal and available in developing country like ours will surely aid health care providers to screen, diagnose GDM and offer preventive and treatment measures at the earliest.
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Riaz, Musarrat, Asmat Nawaz, Shabeen Naz Masood, Asher Fawwad, Abdul Basit, and A. S. Shera. "Frequency of gestational diabetes mellitus using DIPSI criteria, a study from Pakistan." Clinical Epidemiology and Global Health 7, no. 2 (June 2019): 218–21. http://dx.doi.org/10.1016/j.cegh.2018.06.003.

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Rouco, Victor, Raissa Franssens, and Barbara De Clercq. "A brief version of the DIPSI maladaptive trait measure for children and adolescents." Psychological Assessment 33, no. 9 (September 2021): 880–89. http://dx.doi.org/10.1037/pas0001032.

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Jaggi, Shalini, Shubhaa Chawla, Aastha Chawla Trehan, Siddhant Trehan, and Rajeev Chawla. "Abstract #1003366: Maternal and Foetal Outcomes in IADPSG Vs DIPSI based diagnosed GDM." Endocrine Practice 27, no. 6 (June 2021): S49. http://dx.doi.org/10.1016/j.eprac.2021.04.574.

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Seshiah, V., N. Bhavatharini, Sanjeev V. K., Changanidi A. R. A., and R. Aruyerchelvan. "Problems and solutions for the diagnosis of gestational diabetes mellitus in non metropolitan areas in India." International Journal Of Community Medicine And Public Health 7, no. 4 (March 26, 2020): 1607. http://dx.doi.org/10.18203/2394-6040.ijcmph20201482.

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Management of gestational diabetes mellitus and hyperglycemia in pregnancy is challenging in developing country like India. There are several logistic, socioeconomic and cultural issues faced by the care providers and the patients alike. In order to tackle these challenges, Diabetes in Pregnancy Study Group of India (DIPSI) recommendations consisting of a single glucose challenge test is ideal to evaluate the glucose intolerance and early initiation of doctors’ prescription. This review article explores the practical challenges associated with managing gestational diabetes mellitus and recommendations to overcome these challenges in the public health system.
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Jadhav, Deepali S., and Uma N. Wankhede. "Study of maternal, fetal and neonatal outcomes in patients with gestational diabetes mellitus in a tertiary care hospital." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 7 (June 24, 2017): 3014. http://dx.doi.org/10.18203/2320-1770.ijrcog20172926.

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Background: GDM is defined as carbohydrate intolerance of variable severity with onset or first recognition during pregnancy. Women with gestational diabetes are characterized by a relatively diminished insulin secretion and pregnancy induced insulin resistance primarily present in the skeletal muscle tissue. Normal pregnancy is a diabetogenic state characterized by exaggerated rate and amount of insulin release, associated with decreased sensitivity to insulin at cellular levels. The objective of the study was to study the maternal, the fetal and the neonatal outcomes of treated patients of GDM in present study.Methods: It was a hospital based clinical study. 1000 patients were enrolled between 24-28 weeks of gestation and DIPSI test was performed. Diagnosis of GDM was done using DIPSI criteria. 80 patients were diagnosed with GDM and followed till delivery to study the maternal, fetal and neonatal outcome.Results: Elderly patients, patients with previous history of GDM, patients with family history of diabetes, patients with high BMI and patients with polyhydramnios are at high risk for GDM.Conclusions: Hypertensive disorders and preterm birth are known to be higher with GDM are similar to the non-GDM group suggesting that early diagnosis and prompt treatment and maintaining strict glycemic control by patient may be beneficial. GDM can be managed well on MNT and lifestyle modifications, only few patients required insulin therapy. In spite of appropriate glycemic control, the incidence of macrosomia found to be high in GDM group. Sudden unexplained stillbirth can occur in spite of strict glycemic control. Neonatal complications have occurred despite well glycemic control.
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Jain, Meenal, Shikha Singh, Latika Pant, and Garima Singh. "Evaluation of Validity and Efficacy of DIPSI Criteria for Screening of Gestational Diabetes Mellitus." International Journal of Current Research and Academic Review 4, no. 5 (May 20, 2016): 27–33. http://dx.doi.org/10.20546/ijcrar.2016.405.004.

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Polur, Havilah, K. Prasad, Pandit Bandela, Hindumathi, and Shaik Saheb. "Diabetes in Pregnancy Study Group in India (DIPSI) – A Novel Criterion to Diagnose GDM." International Journal of Biochemistry Research & Review 10, no. 1 (January 10, 2016): 1–6. http://dx.doi.org/10.9734/ijbcrr/2016/22624.

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S D, Prathibha, Rashmi K, Anitha N, and Megha H. Chowhan. "COMPAR A TIVE STUDY OF EFFICACY OF DIPSI AND O’SULLIVAN’S METHOD OF SCREENING FOR GDM." Journal of Evidence Based Medicine and Healthcare 2, no. 9 (February 26, 2015): 1289–94. http://dx.doi.org/10.18410/jebmh/2015/185.

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Arneodo, M., L. Lamberti, and M. Ryskin. "DIPSI: a Monte Carlo generator for elastic vector meson production in charged lepton-proton scattering." Computer Physics Communications 100, no. 1-2 (February 1997): 195–214. http://dx.doi.org/10.1016/s0010-4655(96)00102-6.

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Cavanagh, John, and Mark Rance. "Suppression of cross-relaxation effects in TOCSY spectra via a modified DIPSI-2 mixing sequence." Journal of Magnetic Resonance (1969) 96, no. 3 (February 1992): 670–78. http://dx.doi.org/10.1016/0022-2364(92)90357-d.

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Sharma, Neeraj, Seema Pundir, and Bunty Dinani. "Can single plasma glucose value 2 hours after 75g glucose (DIPSI criteria) replace the gold standard OGTT for the diagnosis of gestational diabetes mellitus?" International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 3 (February 26, 2019): 1041. http://dx.doi.org/10.18203/2320-1770.ijrcog20190877.

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Background: Gestational diabetes mellitus is a common medical complication of pregnancy associated with several fetal and maternal complications. There are several screening tools for detecting gestational diabetes mellitus including recent DIPSI criteria of non-fasting single plasma 2-hour value after 75 grams glucose (single step test). The present study was aimed at calculating prevalence of GDM, sensitivity and specificity using non-fasting single plasma 2-hour value after 75 grams glucose for screening and diagnosis of gestational diabetes mellitus and to study the high-risk characteristics for GDM in this study population.Methods: This was a prospective study conducted for a period of one year. 750 antenatal women attending Antenatal outpatient department(OPD) with period of gestation 24-28 weeks were enrolled in the study. All women were first tested by 75 gm glucose and then by OGTT for confirmation. Prevalence rates, sensitivity, specificity, positive predictive value and negative predictive value were studied. History based questionnaire was used to study the risk characteristics for GDM.Results: Prevalence rate, sensitivity, specificity, positive predictive value and negative predictive value for patients were 14.13%, 73.58%, 95.03%, 70.90% and 95.67%. Among the risk factors 7.2% patients were more than 30 years in age. 0.93% had GDM in previous pregnancy.4.21% had GCA in previous pregnancy, 12.4% had SB/IUD/NND in previous pregnancy. 1.17% had previous pregnancy with birth weight more than 3.5 kg and 9.73% had family history of diabetes mellitus. Past history of GDM (50%) was the most common risk factor in GDM group followed by age > 30 years (29.6%), and family history (24.6%).Conclusions: Screening using DIPSI criteria has good sensitivity and negative predictive values. It can serve as both screening and diagnostic test besides being simple, user friendly, cost effective and evidence-based test in less resource countries like India.
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Gayam, Susheela, Dr Paaka Madhurima, Dr Sashikala Paul, and Dr Mythili Tallavajhula. "The validity of single step test (DIPSI) for screening for GDM in all trimesters of pregnancy." Obsgyne Review: Journal of Obstetric and Gynecology 1, no. 2 (December 31, 2015): 34–38. http://dx.doi.org/10.17511/joog.2015.i02.02.

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Elancheran, Saranya, and Sankareswari Raja. "A COMPARATIVE STUDY OF EFFICACY OF DIPSI AND O’SULLIVAN'S METHOD OF SCREENING FOR GESTATIONAL DIABETES MELLITUS." Journal of Evolution of Medical and Dental Sciences 6, no. 04 (January 12, 2017): 290–95. http://dx.doi.org/10.14260/jemds/2017/66.

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Mahajan, Mamta, Amit Gupta, Anju Vij, and Aanchal Gupta Sharma. "Pregnancy outcome in pre-gestational and gestational diabetic women: a prospective observational study." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, no. 8 (July 26, 2021): 3040. http://dx.doi.org/10.18203/2320-1770.ijrcog20212951.

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Background: India is considered the world capital of diabetes, proper care and management of the same is the demand of society. The present study is carried out to identify the disease burden of GDM/ overt DM among antenatal cases. The main objective was to study the maternal and fetal outcome of diabetes complicating pregnancy.Methods: The present study was conducted at Dr. Rajendra Prasad Government Medical College at Tanda, District KangraHP from October 2015 to September 2016. All antenatal cases were screened for diabetes by OGTT 75 gm, 2-hour blood glucose level as per DIPSI guidelines and labelled as GDM/ overt DM. Those who fulfilled selection criteria were enrolled in the study. A total of 6452 cases who attended antenatal clinic during the study duration and were screened were selected for the study. 116 cases were found to have GDM / overt DM. Seventy-nine had GDM with OGTT>140 mg/dl (DIPSI guidelines) and 37 had overt DM with 2 hours PP >200 mg/dl (WHO criteria). Total 100 cases comprised of study group were followed till delivery to study maternal and fetal outcome.Results: The prevalence of diabetes in pregnancy was found to be low 1.79%. GDM was found to be more prevalent than overt diabetes in pregnant women (66% versus 34%). Among the antenatal maternal complications observed missed abortion (11.8% versus 1.55; p=0.026), polyhydraminos (26.4% versus 10.6%; p=0.04) and preterm labour (17.6% versus 4.5%; p=0.003) were significantly more common in overt diabetics than GDM cases. IUFD (8.8% versus 0; p=0.014) was also significantly more common in overt diabetics than GDM case. RDS was found significantly higher in neonates of overt diabetics as compared to GDM mothers (14.7 % versus 1.5%; p=0.009).Conclusions: Early detection and good glycemia control by MNT and insulin, regular antenatal check-ups, patient counselling and compliance, intrapartum fetal monitoring and early neonatal care are keys to improved outcome.
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Somalwar, Savita, Preksha Jain, and Pritesh Jain. "Neonatal Outcome and Its Correlation with Hemoglobin A1c in Gestational Diabetes Mellitus." Journal of South Asian Federation of Obstetrics and Gynaecology 9, no. 3 (August 2017): 216–20. http://dx.doi.org/10.5005/jp-journals-10006-1498.

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ABSTRACT Aim To determine neonatal outcome in women with gestational diabetes mellitus (GDM) diagnosed using Diabetes in Pregnancy Study Group of India (DIPSI) recommended method. Materials and methods Out of 487 antenatal women, 52 were diagnosed with GDM using DIPSI test. All women were followed up until delivery and evaluated for neonatal outcome and managed accordingly. The appropriate statistical tests for various variables were applied by using Epi Info 7 software and evaluated at the level below than 5%. Results Apgar score of <6 at 5 minutes was found in 10 (20%) neonates of GDM mothers as compared with 18 (4.1%) in non-GDM group (p-value of 0.00001). Respiratory distress was present in 19 (38%) neonates in GDM group, while it was 48 (11.1%) in non-GDM group (p-value of 0.00002). Association of GDM and hyperbilirubinemia was nonsignificant in 2 (4%) neonates among GDM group, while it was 6 (1.4%) in non-GDM group. Hypoglycemia was 5 (10%) in GDM group, while 3 (0.7%) in non-GDM group (p-value of <0.0003). A total of 3 (6%) among GDM group had hypocalcemia, while 3 (0.7%) had hypocalcemia in non-GDM group (p-value of 0.02). The neonatal intensive care unit admissions were 29 (58%) in GDM group, while it was 96 (22.1%) neonates belonging to non-GDM group (p-value of 0.00001). No neonatal deaths were reported in GDM group, while there were 2 (0.5%) in non-GDM group. Anomalies were found in 6 (11.5%) in GDM group as compared with 5 (1.1%) in non-GDM (p-value of 0.00001). About 44.2% women with GDM had hemoglobin (Hb)A1c levels between 6 and 6.9%. Among GDM women, 4 (7.7%) had pregnancy losses as compared with 7 (1.6%) in non-GDM group. Conclusion The GDM is associated with significant fetal and neonatal morbidity; hence, preconceptional counseling, early diagnosis, and proper treatment are recommended. Clinical significance Preconceptional correction of HbA1c is also recommended based on risk of anomalies in fetus of GDM mother. How to cite this article Jain P, Somalwar S, Jain P. Neonatal Outcome and Its Correlation with Hemoglobin A1c in Gestational Diabetes Mellitus. J South Asian Feder Obst Gynae 2017;9(3):216-220.
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Singh, Abha, Avinashi Kujur, and Archana Roy. "Body mass index and gestational weight gain in pregnant women with gestational diabetes and its relation with adverse maternal and fetal outcome." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 10 (September 25, 2020): 4256. http://dx.doi.org/10.18203/2320-1770.ijrcog20204323.

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Background: Raised body mass index (BMI) and excessive gestational weight gain (GWG) are important determinants in development of gestational diabetes.Methods: A prospective, observational study carried out on antenatal women since their first trimester. These women were screened for gestational diabetes mellitus (GDM) by diabetes in pregnancy study group of India (DIPSI) criteria. All participants were followed up by measuring their BMI, weight gain, blood sugars in every trimester. Also, data was collected regarding any adverse outcomes.Results: Among all participants, 16.8% were diagnosed as GDM. 44% women of study group had weight gain beyond Institute of Medicine (IOM) recommendations. Higher risk of GDM was observed in women with raised BMI and excessive GWG. Also, odds of preeclampsia, preterm deliveries, caesarean section, macrosomia, intrauterine fetal death, neonatal intensive care unit (NICU) admissions were higher in women with GDM.Conclusions: Compliance of recommended weight gain during pregnancy have a strong impact on the fetal outcome. Amount and timing of weight gain plays a crucial role in GDM.
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Vij, Pulkit, Sujeet Jha, S. K. Gupta, Anjila Aneja, Rajani Mathur, Swati Waghdhare, and Manju Panda. "Comparison of DIPSI and IADPSG criteria for diagnosis of GDM: a study in a north Indian tertiary care center." International Journal of Diabetes in Developing Countries 35, no. 3 (January 20, 2015): 285–88. http://dx.doi.org/10.1007/s13410-014-0244-5.

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Saxena, Pikee, Puja Verma, and Binita Goswami. "Comparison of Diagnostic Accuracy of Non-fasting DIPSI and HbA1c with Fasting WHO Criteria for Diagnosis of Gestational Diabetes Mellitus." Journal of Obstetrics and Gynecology of India 67, no. 5 (February 20, 2017): 337–42. http://dx.doi.org/10.1007/s13224-017-0962-y.

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Mishra, Surabhi, Chythra R. Rao, and Avinash Shetty. "Trends in the Diagnosis of Gestational Diabetes Mellitus." Scientifica 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/5489015.

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Introduction. Gestational diabetes mellitus (GDM) is defined as carbohydrate intolerance of variable degree with onset or recognition during pregnancy. As prevalence of diabetes is linked to impaired glucose tolerance during antenatal period, routine antenatal screening of GDM is required. However, screening tests for GDM remain controversial.Objective. To review different diagnostic criteria for GDM.Materials and Methods. Freely accessible, full-text articles from 1964 to 2015, available in PubMed in English language, pertaining to screening of GDM were reviewed.Results. First diagnostic criteria for GDM in 1964 by O’Sullivan and Mahan, modified by the National Diabetes Data Group (NDDG) in 1979 and Carpenter in 1982. The cut-off value as per WHO definition of GDM was 140 mg/dL, 2 hours after 75 g glucose intake. Diabetes in Pregnancy Study Group India (DIPSI), in 2006, endorsed WHO criteria but irrespective of the last meal timings. Being cost-effective, it formed the basis of national guidelines for Indians in 2014.Conclusions. As typical clinical scenarios are usually varied, practical guidelines that meet the constraints of low-resource settings like India are required.
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Uikey, Prashant Arun, Sayalee Vivek Pathak, Megha Pandurang Tajne, and Saurabh Chandrakant Sankalecha. "A Comparative Study of DIPSI and O’Sullivan's Method for Screening of Gestational Diabetes Mellitus and Its Efficacy in Predicting Foetomaternal Outcome." Journal of Evidence Based Medicine and Healthcare 7, no. 34 (August 24, 2020): 1780–88. http://dx.doi.org/10.18410/jebmh/2020/370.

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G S, Anitha, Rashmi K, Tejaswini D, Radhika, and Sukanya S. "A comparative study of efficacy of DIPSI and O’Sullivan’s method of screening for GDM in a high risk tertiary referral hospital." Indian Journal of Obstetrics and Gynecology Research 8, no. 1 (March 15, 2021): 103–6. http://dx.doi.org/10.18231/j.ijogr.2021.021.

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There is an increasing trend of making Diabetes one of the most common non-communicable diseases globally. Gestational Diabetes Mellitus (GDM) is defined as “carbohydrate intolerance variable severity that is first diagnosed during present pregnancy, regardless of the need for insulin or persistence of the diabetic state after delivery”. Diabetes Mellitus is the most common disorder of pregnancy, although the prevalence is usually reported as 2 to 5% of pregnant women, it can be as high as 14% in high risk groups. To note the Foetal Outcome of pregnancy with impaired and abnormal glucose tolerance detected with DIPSI.Total of 200 patients was included in the study from Vanivilas hospital for 1 year. A detailed history from antenatal patients was taken to reveal all risk factors. The procedure of the study was explained and required consent for the study was taken. Examination of the patients was done and all relevant data was obtained. Fasting blood glucose was taken of all antenatal patients at their first visit. Pregnant women at 24-28 weeks were tested with 50g oral glucose load or 75g oral glucose load, at random. Patients were give 50g glucose irrespective of the meal and 1 hour venous blood sample was collected. Patients of 75 g of oral glucose were asked to come in fasting state, 75g of glucose was given, and following which 2 hour venous sample was collected. Blood glucose was tested by GOD-POD method. Diagnosis of GDM was made when the plasma glucose of &#62;140mg/dL and impaired glucose tolerance diagnosis was made when plasma glucose was between 120-140mg/dl. High prevalence rate of GDM was obtained in our study, GDM has adverse maternal and fetal outcome. GDM when identification early and treatment initiated for mothers, maternal and fetal complications can be reduced. In conclusion, intensive care of GDM mothers can help primary prevention of obesity, impaired glucose tolerance and diabetes in the offspring.
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47

Patil, Shraddha, and Sushma Sharma. "Role of DIPSI guidelines as a universal screening as well as diagnostic tool for gestational diabetes mellitus in rural tertiary health care centre." International Journal of Clinical Obstetrics and Gynaecology 3, no. 4 (July 1, 2019): 92–96. http://dx.doi.org/10.33545/gynae.2019.v3.i4b.297.

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48

Nimavat, Nirav K., Roma S. Dadwani, and Girija P. Kartha. "Prevalence of gestational diabetes mellitus and associated risk factors amongst antenatal women attending urban health centre of Rajkot City, Gujarat." International Journal Of Community Medicine And Public Health 6, no. 7 (June 28, 2019): 3033. http://dx.doi.org/10.18203/2394-6040.ijcmph20192848.

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Background: Prevalence of gestational diabetes mellitus (GDM) vary widely depending on the region of the country, dietary habits, and socio-economic status. This study was undertaken to determine the prevalence of GDM and risk factors associated with it, in women attending an antenatal care (ANC) clinic at urban health training center in Rajkot city, Gujarat.Methods: This study enrolled women, with estimated gestational age between 24 and 28 week, attending UHC in Rajkot. After informing, women who consented to participate were given a standardized 75 g oral glucose tolerance test (OGTT). A proforma containing general information on demographic characteristics, socio-economic status, education level, parity, family history of diabetes and/or hypertension was filled up. Diabetes in pregnancy study group India (DIPSI) criteria for 75 g 2-h OGTT was used for diagnosing GDM.Results: Total of 366 women participated in the study and GDM was diagnosed in 36 (9.8%) women. Age, parity, BMI, family history of DM and hypertension were accessed and found to be not significant. History of hypertension in previous pregnancy was statistically significant with occurrence of GDM in present pregnancy.Conclusions: The prevalence of GDM was found to be 9.8 per cent in a UHC, Rajkot. Appropriate interventions are required for control of GDM and modifications of risk factors.
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49

Jain, Rajesh, Susanne Olejas, Lee Sam Goo, N. Bhavatharinin, Ashish S. Dengra, Reza Shoghli, Sanjeev Davey, and Rachna Jain. "Review of FIGO & ADA, WHO, IADPSG Guidelines for GDM for Low Resource Setting and Integration of DIPSI with MOHFW Govt of India, Guidelines." International Journal of Diabetes and Endocrinology 4, no. 3 (2019): 73. http://dx.doi.org/10.11648/j.ijde.20190403.12.

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50

Ardhapurkar, Surabhi S., Shailesh J. Kore, and Pradnya A. Supe. "Screening of gestational diabetes mellitus: comparison of glucose challenge test done in non fasting state (DIPSI criteria) and fasting state (WHO criteria): a prospective study." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 9, no. 12 (November 26, 2020): 4918. http://dx.doi.org/10.18203/2320-1770.ijrcog20205221.

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Background: The recent data shows 16.55% prevalence of gestational diabetes mellitus in India. Hence universal screening has become important and we need a simple procedure which is economical and feasible to perform in the Indian context. The comparison of screening methods for gestational diabetes mellitus by 75 gm oral glucose challenge testing done in fasting state (WHO) and non-fasting (DIPSI) state was done.Methods: Cross sectional prospective study done on 225 antenatal women between 20-24 weeks coming to tertiary level hospital in a single working unit were included. They were subjected to two screening glucose challenge tests for detection of gestational diabetes mellitus. Results of glucose challenge tests using 75 gm of anhydrous glucose done in fasting and non fasting state were compared. Values of standard 100 gm oral glucose tolerance test done were considered gold standard.Results: The prevalence of gestational diabetes mellitus was found to be 12.4% by oral glucose tolerance testing. Glucose challenge test with 75 gm done in fasting state was abnormal in 14.7% and abnormal in 15.6% done in non fasting state. The sensitivity of 75 gm GCT done in fasting was 60.7% and the sensitivity of 75 gm GCT done in non fasting state was 67.9%. The specificity of 75 gm GCT done in fasting state was 91.9% and the specificity of 75 gm GCT done in non fasting state was 91.9%.Conclusions: Sensitivity and specificity of the screening tests done by 75 gm GCT done in non fasting state is comparable with screening done in fasting state. Screening done by 75 gm GCT done in non fasting state is convenient and more feasible in Indian setup.
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