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Journal articles on the topic 'Direct Compression Method'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Astriani Nurjanah and Neni Nurlelah. "Formulation and Physical Evaluation of CTM Tablets by Direct Compression Method: A Systematic Literature Review." Eureka Herba Indonesia 4, no. 4 (2023): 305–9. http://dx.doi.org/10.37275/ehi.v4i4.88.

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The direct compression method is one of the well-known formulation approaches in tablet manufacture. In this method, the active ingredients and additives of the formulation are mixed together and then compressed into tablets using a special device such as a compression machine. This study is a systematic review that aims to explore the formulation and physical evaluation of CTM tablets by direct compression method. The literature search process was carried out on various databases (PubMed, Web of Sciences, EMBASE, Cochrane Libraries, and Google Scholar) regarding the formulation and physical e

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Jaiswal, Anamika, Ashok Koshta, Sapna Malviya, and Anil Kharia. "Formulation and Evaluation of Colon Targeted Matrix Tablets of Mesalazine." American Journal Of Pharmacy And Health Research 10, no. 12 (2022): 23–36. https://doi.org/10.5281/zenodo.7479322.

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ABSTRACT The present work involves the formulation of colon targeted matrix tablet of Mesalazine by using direct compression method. Excipients including in the formulation are Eudragit S100, Ethyl cellulose, Lactose, Talc, Magnesium stearate. Preformulation studies have also been performed to study the nature of API and compatibility of API with excipients by physical observation and TLC studies. The result showed that API was compatible with all the excipients selected. The tablets were formulated by direct compression method using the selected excipient quantities. The formulated tablets we

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Moselhi, Osama. "Schedule compression using the direct stiffness method." Canadian Journal of Civil Engineering 20, no. 1 (1993): 65–72. http://dx.doi.org/10.1139/l93-007.

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This paper presents a new method for critical path (CPM) scheduling that optimizes project duration in order to minimize the project total cost. In addition, the method could be used to produce constrained schedules that accommodate contractual completion dates of projects and their milestones. The proposed method is based on the well-known "direct stiffness method" for structural analysis. The method establishes a complete analogy between the structural analysis problem with imposed support settlement and that of project scheduling with imposed target completion date. The project CPM network

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Sun, Tongjing, Ji Li, and Philippe Blondel. "Direct Under-Sampling Compressive Sensing Method for Underwater Echo Signals and Physical Implementation." Applied Sciences 9, no. 21 (2019): 4596. http://dx.doi.org/10.3390/app9214596.

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Compressive sensing can guarantee the recovery accuracy of suitably constrained signals by using sampling rates much lower than the Nyquist limit. This is a leap from signal sampling to information sampling. The measurement matrix is key to implementation but limited in the acquisition systems. This article presents the critical elements of the direct under-sampling—compressive sensing (DUS–CS) method, constructing the under-sampling measurement matrix, combined with a priori information sparse representation and reconstruction, and we show how it can be physically implemented using dedicated

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Sachan, Anupam Kumar. "Comparative Study of Natural and Synthetic Superdisintegrants in Orodispersible Metformin Tablet." Asian Journal of Pharmaceutical Research and Development 7, no. 3 (2019): 46–53. http://dx.doi.org/10.22270/ajprd.v7i3.509.

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Objective: The main objective of this study is comparative study of natural and synthetic superdisintegrants in orodispersible Metformin tablet by using direct compression method and wet granulation method. Method: Orodispersible Metformin tablet were prepared by wet granulation method and direct compression method by using different synthetic and natural superdisintegrants. Orodispersible tablets (ODTs) have received more interest in the pharmaceutical industry for their easy to use and self medication. ODTs overcome the problem of dysphagia (difficulty in swallowing) in the all group a

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Ponnaganti, Hyma, and Kaveri Anke. "FORMULATION AND EVALUATION OF ORODISPERSIBLE TABLETS OF ACECLOFENAC BY DIRECT COMPRESSION METHOD." Journal of Advanced Scientific Research 13, no. 02 (2022): 142–48. http://dx.doi.org/10.55218/jasr.202213219.

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Nowadays, Oro dispersible tablets are gaining much importance because it is easily approachable and due to its patient compliance. In this study, Formulation and evaluation of one such tablets of Aceclofenac by direct compression method using super disintegrants like Cross carmellose sodium (CCS) was performed. Due to low water soluble property of aceclofenac, it has poor dissolution and bioavailability. In order to minimize this property OTD’s are prepared. ODT’s were prepared by direct compression method using super disintegrant i.e Cross Carmellose Sodium (CCS) in different concentrat

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Becque, Jurgen, Maura Lecce, and Kim J. R. Rasmussen. "The direct strength method for stainless steel compression members." Journal of Constructional Steel Research 64, no. 11 (2008): 1231–38. http://dx.doi.org/10.1016/j.jcsr.2008.07.007.

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Foks, Nathan Leon, Richard Krahenbuhl, and Yaoguo Li. "Adaptive sampling of potential-field data: A direct approach to compressive inversion." GEOPHYSICS 79, no. 1 (2014): IM1—IM9. http://dx.doi.org/10.1190/geo2013-0087.1.

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Compressive inversion uses computational algorithms that decrease the time and storage needs of a traditional inverse problem. Most compression approaches focus on the model domain, and very few, other than traditional downsampling focus on the data domain for potential-field applications. To further the compression in the data domain, a direct and practical approach to the adaptive downsampling of potential-field data for large inversion problems has been developed. The approach is formulated to significantly reduce the quantity of data in relatively smooth or quiet regions of the data set, w

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Naveed, Safila, Huma Dilshad, and Fatima Qamar. "Manufacturing of new formulation of Pyridoxine HCL by direct compression method." Journal of Scientific and Innovative Research 3, no. 4 (2014): 450–53. http://dx.doi.org/10.31254/jsir.2014.3409.

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Vitamins are widely used as a prescription medicine. The aim of the study is to prepare pyridoxine HCl tablets (200 mg) using direct compression technique which is now a days considered a cost effective and simple method of formulation. It can be considered as an appropriate method for hygroscopic and thermolabile substances. In the present study new formulations of Pyridoxine HCl was manufactured by direct compression method using Lactose, magnesium stearate. The present study is divided into two phases. In the first phase new formulation of Pyridoxine HCl was prepared by direct compression m

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Polishetty, Saipriya* Mariyam Suryaprakash Reddy SK. Irfan Khan Afshan Urooj Dr. Y. Krishna Reddy Dr.K. N. V. Rao Dr. K. Rajeswar Dutt. "FORMULATION, OPTIMIZATION AND EVALUATION OF ESLICARBAZEPINE ACETATE." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 03 (2018): 1688–93. https://doi.org/10.5281/zenodo.1209355.

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The present study aims at developing an Eslicarbazepine fast dissolving tablet formulation for the effctive treatment of Epilepsy. To provide the patient with the most convenient mode of administration, FDT’s will dissolve quickly. A Eslicarbazepine is absorbed to atleast 90% from the gut, independently of food intake. It is quickly metabolized to esclicarbazepine. So the present work was aimed at formulating fast dissolving tablet for Eslicarbazepine, total 6 formulations were developed by using synthetic superdisintigrants like cross caramellose sodium, Crosspovidone, sodium starch gly

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Luo, Qiuhua, Qianying Zhang, and Puxiu Wang. "Hydrochlorothiazide/Losartan Potassium Tablet Prepared by Direct Compression." Pharmaceutics 14, no. 8 (2022): 1741. http://dx.doi.org/10.3390/pharmaceutics14081741.

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Hydrochlorothiazide (HCTZ)/losartan potassium (LOS-K) was used as a model drug to prepare compound tablets through the investigation of the compression and mechanical properties of mixed powders to determine the formulation and preparation factors, followed by D-optimal mixture experimental design to optimize the final parameters. The type and amount of lactose monohydrate (SuperTab®14SD, 19.53–26.91%), microcrystalline cellulose (MCC PH102, 32.86–43.31%), pre-gelatinized starch (Starch-1500, 10.96–15.91%), and magnesium stearate (0.7%) were determined according to the compressive work, stress

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Patel, Sarvesh, Jai Narayan Mishra, and Dhaneswar Kumar Vishwakarma. "FORMULATION DEVELOPMENT AND CHARACTERIZATION OF FAST DISSOLVING TABLET OF ATENOLOL BY DIRECT COMPRESSION METHOD." International Journal of Advanced Research 9, no. 10 (2021): 1277–86. http://dx.doi.org/10.21474/ijar01/13678.

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Finally in the project work Atenolol is an anti-hypertensive drug. It has been formulated into fast dissolving tablets by direct compression method by using the Excipients like lactose, sucrose magnesium stearate, sodium lauryl and sulphate and many type super disintegrates such as crosscarmellose and sodium starch glycolate and the prepared by the tablets were evaluated for the pre-compression parameter such as angle of repose, bulk density, tapped density, % index, Hausners ratio, partition coefficients, melting points, UV spectroscopy, % assay, TLC, loss on drying and post compression param

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ITO, AKIHIKO, YUMIKO ARAKI, and MASAYASU SUGIHARA. "Dividing Property of Scored Tablet Produced by Direct Compression Method." Japanese Journal of Hospital Pharmacy 17, no. 4 (1991): 204–10. http://dx.doi.org/10.5649/jjphcs1975.17.204.

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Kumar, Inder, Dipima Chaudhary, Bhumika Thakur, and Vinay Pandit. "Formulation and Evaluation of Piroxicam Fast Dissolving Tablets Using Direct Compression and Sublimation Method." Journal of Drug Delivery and Therapeutics 10, no. 3-s (2020): 17–25. http://dx.doi.org/10.22270/jddt.v10i3-s.4063.

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Objective: In the present research work, fast dissolving tablets of Piroxicam were formulated by two different techniques i.e. direct compression method and sublimation method using different superdisintegrants. Methods: Twelve formulations were prepared (PXM1 to PXM12) in which first six formulation were prepared by direct compression technique and other six formulation were prepared by sublimation method by using camphor as a sublimating agent. Result and Discussion: All the formulations were subjected for precompression, post compression parameters, and shows all the data within

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Moser, B., K. Wasmer, L. Barbieri, and J. Michler. "Strength and fracture of Si micropillars: A new scanning electron microscopy-based micro-compression test." Journal of Materials Research 22, no. 4 (2007): 1004–11. http://dx.doi.org/10.1557/jmr.2007.0140.

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A novel method for in situ scanning electron microscope (SEM) micro-compression tests is presented. The direct SEM observation during the instrumented compression testing allows for very efficient positioning and assessment of the failure mechanism. Compression tests on micromachined Si pillars with volumes down to 2 μm3are performed inside the SEM, and the results demonstrate the potential of the method. In situ observation shows that small diameter pillars tend to buckle while larger ones tend to crack before failure. Compressive strength increases with decreasing pillar diameter and reaches

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Dinu, Paul-Octavian, Ion Pana, and Florinel Dinu. "A METHOD TO DETERMINE THE MASS FLOW TO RECIPROCATING COMPRESSORS." Romanian Journal of Petroleum & Gas Technology 3 (74), no. 2 (2022): 5–16. http://dx.doi.org/10.51865/jpgt.2022.02.01.

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To establish the mass flow to a reciprocating compressor there are several relationships used in the construction and analysis of these types of compressors. The use of relationships is based on the geometric elements of the compressor. It is also necessary to know the composition of the gas and the operating conditions with which: the adiabatic exponent, the volumetric efficiencies and the compressibility factor are determined. The paper aims to establish the compressor mass flow with the help of modern means. The modeling was done in the LMS Amesim program. We use elements from the library o

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Dr. Payal N. Vaja, Dr Payal N. Vaja, and Mr Uttamkumar V. Rakholiya Mr. Uttamkumar V. Rakholiya. "Formulation and Optimization of Fast Dissolving Tablets of Omeprazole Using Design of Experiments (DoE) Approach." International Journal of Pharmaceutical Research and Applications 10, no. 3 (2025): 1550–61. https://doi.org/10.35629/4494-100315501561.

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Objective The main objective of this study was to formulate and evaluate fast dissolving tablets of Omeprazole using direct compression and wet granulation methods and to compare their performance based on various physicochemical parameters and compare the drug release profiles of different formulations to identify the most effective formulation for rapid disintegration and maximum drug release. Method Formulations were developed using direct compression method and formulation variables such as superdisintegrant and binder concentrations were optimized using Box-Behnken Design (BBD). The table

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M., Asha Rani 1. *. H.N. Chaya 1. T. Chakraborty 2. Dr. C.S.R. Lakshmi 1. Dr. L.V.G. Nargund 1. "DESIGN AND DEVELOPMENT OF ORALLY DISINTEGRATING TABLETS OF QUETIAPINE FUMARATE BY DIRECT COMPRESSION METHOD." Journal of Pharma Research 7, no. 7 (2018): 175–78. https://doi.org/10.5281/zenodo.1322962.

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<strong><em>ABSTRACT</em></strong> <strong><em>Q</em></strong><em>uetiapine Fumarate is a (atypical antipsychotic) psychotropic agent that belongs to the dibenzothiazepine class used for the treatment for schizophrenia. Patients, particularly pediatric and geriatric patients, have difficulty in swallowing solid dosage forms thus orodispersible drug delivery system have the combined advantages of both liquid and conventional tablet formulation and offer added advantage over both the traditional dosage form. In the present work orodispersible tablets of Quetiapine Fumarate were prepared by direc

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Khaleel, Shahbaa. "Image Compression Using Swarm Intelligence." International Journal of Intelligent Engineering and Systems 14, no. 1 (2021): 257–69. http://dx.doi.org/10.22266/ijies2021.0228.25.

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As a result of the development in multimedia technology and direct dealing with it in social media, it has led to interest in the techniques of compacting color images because of their importance at present. Since image compression enables the representation of color image data with the fewest number of bits, which reduces transmission time in the network and increases transmission speed. To ensure the compression process is performed without loss of data, the lossless compression methods are used because no data is lost during the compression process. In this research, a new system was presen

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Kwari, J. H., A. K. Olowosulu, and A. R. Oyi. "Evaluation of Processing Methods for Formulated Tablets of <i>Loranthus micranthus</i>." Nigerian Journal of Pharmaceutical Research 19, no. 1 (2023): 11–22. http://dx.doi.org/10.4314/njpr.v19i1.2.

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Background: Loranthus micranthus is one of the many plants that has documented evidence of safety and efficacy in the management of many ailments and widespread use in almost every part of Nigeria. It is desirable to formulate it into a suitable dosage form for use by the populace. Objectives: The research was aimed at formulating the aqueous leaf extract of L. micranthus into a tablet dosage form by wet granulation and direct compression methods. Methods: For wet granulation method, maize starch, gelatin, polyvinyl pyrrolidone and acacia were used as binders for the formulations e

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Kotsur, Ju M., Ju M. Ladytko, I. A. Narkevich, and E. V. Flisyuk. "Prediction of the composition of prolonged release tablets based on 4,4'-(propandiamido) sodium dibenzoate using the SeDeM method." Drug development & registration 10, no. 4 (2021): 54–62. http://dx.doi.org/10.33380/2305-2066-2021-10-4(1)-54-62.

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Introduction. Direct compression technology is one of the most common tablet technologies. As known, many active pharmaceutical ingredients are not suitable for this technology without the addition of special excipients. A useful tool for determining the suitability of powdered materials for direct compression technology is the Sediment Delivery Model (SeDeM) method, based on the concept of Quality by Design. The presented method allows not only to assess the suitability of a material for direct compression, but also helps to predict the composition of a solid dosage form in the form of a tabl

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Ayorinde, John Oluwasogo, Oludele Adelanwa Itiola, Oluwatoyin Adepeju Odeku, and Michael Ayodele Odeniyi. "Influence of binder type and process parameters on the compression properties and microbial survival in diclofenac tablet formulations." Brazilian Journal of Pharmaceutical Sciences 47, no. 4 (2011): 845–54. http://dx.doi.org/10.1590/s1984-82502011000400022.

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The influence of binder type and process parameters on the compression properties and microbial survival in diclofenac tablet formulations were studied using a novel gum from Albizia zygia. Tablets were produced from diclofenac formulations containing corn starch, lactose and dicalcium phosphate. Formulations were analyzed using the Heckel and Kawakita plots. Determination of microbial viability in the formulations was done on the compressed tablets of both contaminated and uncontaminated tablets prepared from formulations. Direct compression imparted a higher plasticity on the materials than

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An, Myongchol, Suin Ju, and Yongsong Jang. "The method for calculating the bearing capacity of cold-formed C-Section axial compression member using Direct Strength Method." International Journal of Architecture and Urbanism 7, no. 3 (2023): 443–64. http://dx.doi.org/10.32734/ijau.v7i3.13052.

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The paper carried out numerical analysis using experimental and finite element analysis methods to determine the bearing capacity of cold-formed C-section axial compression member. Finite element analysis was performed using the application ABAQUS and the results were compared with experimental measurements. This paper also made out the reason for the error between the experimental results and the results of the finite element analysis, and the ultimate bearing capacity is determined by finite element analysis with C-section axial compression member of various sizes. At the s

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Hazini, Kamran, Reza Dehghan, and Janaka Ruwanpura. "An evolutionary optimization method to determine optimum degree of activity accelerating and overlapping in schedule compression." Canadian Journal of Civil Engineering 41, no. 4 (2014): 333–42. http://dx.doi.org/10.1139/cjce-2013-0194.

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Compressing project schedule using activity accelerating and overlapping requires that an intensive time–cost trade-off analysis be carried out, to determine costs and benefits for each day of compression. However, the cost elements and implications of compression techniques differ significantly, since activity accelerating imposes extra direct cost whereas activity overlapping adds a risk of changes and rework. Such a trade-off becomes even more complicated in capital projects comprised of a large number of schedule activities and relationships. The variety of combinations of accelerating and

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Desu, Prasanna Kumar, Brahmaiah Bonthagarala, and Pasam Venkateswara Rao. "Formulation and evaluation of Nateglinide dispersible tablet by direct compression method." International Journal of Advances in Scientific Research 1, no. 1 (2015): 51. http://dx.doi.org/10.7439/ijasr.v1i1.1784.

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The study was carried to formulate and evaluate dispersible tablet dosage form obtaining Nateglinide.Nateglinideis adrugfor the treatment oftype 2 diabetes. The present study is an attempt to select best possible combination of diluents and disintegrates to formulate dispersible tablet of Nateglinide which disintegrates within few minutes thereby reducing the time of onset of action. Mannitol is selected as diluents, Sodium starch glycol ate, Cross-povidone, cross-carmellose sodium were selected as super disintegrates, citric acid and sodium bi carbonate is effervescent active ingredient in di

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Kumar, M. V. Anil, and V. Kalyanaraman. "Evaluation of Direct Strength Method for CFS Compression Members without Stiffeners." Journal of Structural Engineering 136, no. 7 (2010): 879–85. http://dx.doi.org/10.1061/(asce)st.1943-541x.0000185.

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Bi, Y. X., H. Sunada, Y. Yonezawa, and K. Danjo. "Evaluation of Rapidly Disintegrating Tablets Prepared by a Direct Compression Method." Drug Development and Industrial Pharmacy 25, no. 5 (1999): 571–81. http://dx.doi.org/10.1081/ddc-100102211.

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Ogienko, Andrey G., Elena V. Boldyreva, Andrey Yu Manakov, et al. "A New Method of Producing Monoclinic Paracetamol Suitable for Direct Compression." Pharmaceutical Research 28, no. 12 (2011): 3116–27. http://dx.doi.org/10.1007/s11095-011-0502-x.

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Asif, Uzma, Asif K. Sherwani, Naheed Akhtar, et al. "Formulation Development and Optimization of Febuxostat Tablets by Direct Compression Method." Advances in Polymer Technology 35, no. 2 (2015): 129–35. http://dx.doi.org/10.1002/adv.21536.

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Isaac, Johnson Ajeh, Kokonne Elizabeth Ekere, Ekeh Ezekiel, Isa Hayatu Galadima, Rashida Abdulahi, and Ayuba Samali. "Compressional Physics of Binary Mixture of Dried Andrographis paniculata and Moringa oleifera Leaves." Borneo Journal of Pharmacy 4, no. 4 (2021): 333–44. http://dx.doi.org/10.33084/bjop.v4i4.2544.

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Traditionally, the leafy part of Andrographis paniculata and Moringa oleifera have been widely reported to manage hypertension. Investigation of its pharmacological actions justifies its use. As part of formulation studies to standardize them, this study focused on their compaction and compression properties. Compacts equivalent to 250 mg of A. paniculata and M. oleifera were produced by compressing powders and granules at various compression pressure. Results show that M. oleifera met the WHO limit for ash values. Relative density values for granulated batches were higher, while their moistur

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Jin, Xianwei, Qiaoling Weng, and Jia Min. "To Explore the Haemostatic Effect of Compression Haemostasis Using an Ultrasonic Probe under the Guidance of Ultrasound after Radial Artery Puncture." Disease Markers 2021 (December 1, 2021): 1–7. http://dx.doi.org/10.1155/2021/7423101.

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Objective. To evaluate a new haemostasis method using an ultrasound probe to compress the radial artery and haemostasis under direct vision to replace traditional manual compression of the radial artery. Methods. According to a random number table, 240 patients with gastrointestinal tumours who had undergone arterial puncture were divided into Group A (120 cases) and Group B (120 cases). In Group A, patients were under the guidance of ultrasound to confirm the vascular port, determine the compression position of the ultrasound probe, observe the degree of vascular deformation, and press the ra

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Alsouda, Fadi, Nick S. Bennett, Suvash C. Saha, and Mohammad S. Islam. "A Novel Direct-Expansion Radiant Floor System Utilizing Water (R-718) for Cooling and Heating." Energies 17, no. 17 (2024): 4520. http://dx.doi.org/10.3390/en17174520.

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While forced-air convective systems remain the predominant method for heating and cooling worldwide, radiant cooling and heating systems are emerging as a more efficient alternative. Current radiant cooling systems primarily rely on hydronic chilled water systems. This study introduces direct-expansion radiant cooling as a novel technique that could enhance the efficiency of radiant cooling and reduce its environmental impact. Water (R-718) has been tested as a refrigerant due to its favorable thermodynamic properties and environmental advantages; however, to the author’s knowledge, it has yet

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Chan, Hao Xian Malcolm, Eng Hwa Yap, and Jee Hou Ho. "Axial Compression for Direct Capture of Carbon Dioxide (CO₂)." Applied Mechanics and Materials 284-287 (January 2013): 35–40. http://dx.doi.org/10.4028/www.scientific.net/amm.284-287.35.

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One prospective method to retard the speed of climate change is Carbon Capture and Storage (CCS). It is known that reducing emissions through CCS on point sources can only slowdown the rate of increase of atmospheric CO2 concentration and not able to mitigate the CO2 that are already in the atmosphere by previous emissions. Hence, a complimentary method would be to extract CO2 directly from air – Direct Air Capture (DAC). This paper addresses a novel concept of DAC whereby an additional phase of axial compression is introduced to adapt atmospheric air to a level suitable for capture. An axial

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Ahmad, Shabbir. "To Improvement in Image Compression ratio using Artificial Neural Network Technique." COMPUSOFT: An International Journal of Advanced Computer Technology 03, no. 01 (2014): 1–6. https://doi.org/10.5281/zenodo.14631045.

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 Compression of data in any form is a large and active field as well as a big business. This paper presents a neural network based technique that may be applied to data compression. This paper breaks down large images into smaller windows and eliminates redundant information. Finally, the technique uses a neural network trained by direct solution methods. Conventional techniques such as Huffman coding and the Shannon Fano method, LZ Method, Run Length Method, LZ-77 are discussed as well as more recent methods for the compression of data presents a neural network based technique that may b

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Swapnali, Kawade. "Formulation and Evaluation of Nutraceutical Tablet Using Clove Drugs by Wet Granulation Method." International Journal for Research in Applied Science and Engineering Technology 9, no. 12 (2021): 1626–40. http://dx.doi.org/10.22214/ijraset.2021.39517.

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Abstract: The objective of present study was to formulate and evaluate the nutraceutical tablets with different combination of herbal drugs. Material and Method: The nutraceutical tablet containing lactose and mannitol as diluent and containing natural drugs like clove and cinnamon which was prepared by direct compression method. The compressed formulations were subject to several evaluation parameters like appearance, thickness, weight variation, hardness and friability. Results: The results of all evaluation parameters of nutraceutical tablet were within the acceptable limit. Pre-compression

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Kiran, Reddy, and Anand Kumar Yegnoor. "Preparation and in vitro evaluation of donepezil hydrochloride orodispersible tablets." GSC Advanced Research and Reviews 15, no. 3 (2023): 128–39. https://doi.org/10.5281/zenodo.8269064.

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<strong>Objective</strong>: The present study was aimed to prepare and evaluate Donepezil HCl Orodispersible tablets (DO-ODTs) using natural and synthetic superdisintegrants to increase patient compliance. <strong>Methods</strong>: Direct compression was adapted using crospovidone, croscarmellose sodium as synthetic and mucilage isolated from fruits of Abelmoschus esculentus as natural superdisintegrants at different concentrations along with microcrystalline cellulose and aerosil. The powder mixture were subjected for pre and post compression evaluation including FTIR spectroscopy, micromerit

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Shinohara, A. H., T. Sato, F. Saito, T. Tomioka, and Y. Arai. "A novel method for measuring direct compressive properties of carbon fibres using a micro-mechanical compression tester." Journal of Materials Science 28, no. 24 (1993): 6611–16. http://dx.doi.org/10.1007/bf00356404.

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Rabindra Kumar Rokaya, Kedar Prasad Sah, Stuti Shrestha, et al. "Formulation and evaluation of oral dispersible tablet of nimesulide by direct compression method." Open Access Research Journal of Life Sciences 6, no. 2 (2023): 001–10. http://dx.doi.org/10.53022/oarjls.2023.6.2.0059.

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Based on Biopharmaceutics Classification System (BCS), nimesulide is a class II drug, characterized by low solubility and high permeability. Thus, its dissolution represents a limiting step in the drug absorption process which directly affects the bioavailability of the drug. Oral Dispersible tablets (ODTs) of nimesulide overcome the problem related to dissolution by enhancing the rate of dissolution by decreasing the disintegration time and making it easy to administer to patients who refuse to swallow a tablet. In the present study, different formulations of nimesulide were prepared to vary

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Al-dhahir, Rasha Khalid, and Myasar Al-kotaji. "FORMULATION OF ORALLY DISINTEGRATING TABLETS OF CINNARIZINE BY USING DIRECT COMPRESSION METHOD." International Journal of Applied Pharmaceutics 11, no. 1 (2019): 117. http://dx.doi.org/10.22159/ijap.2019v11i1.29599.

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Objective: The aim of this work was to formulate and evaluate orally disintegrating tablets of cinnarizine that were prepared by direct compression method using different types of diluents and super disintegrants. The rationale behind this work was to accelerate the disintegration of the tablet to provide rapid dissolution, quick action and enhanced bioavailability of the drug.Methods: The tablets were prepared by direct compression method using different types of diluents as mannitol, microcrystalline cellulose (MCC), and lactose. Different super disintegrants were used such as crospovidone (

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Mamatha, T., Naseha, N. Anitha, and Husna K. Qureshi. "Development of Nevirapine Tablets by Direct Compression Method Using Solid Dispersion Technique." Journal of Pharmaceutical Research 16, no. 1 (2017): 72. http://dx.doi.org/10.18579/jpcrkc/2017/16/1/112482.

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Mustarichie, Resmi, and Dradjad Priambodo. "TABLET FORMULATION FROM MENIRAN (PHYLLANTHUS NIRURI L.) EXTRACT WITH DIRECT COMPRESSION METHOD." International Journal of Applied Pharmaceutics 10, no. 4 (2018): 98. http://dx.doi.org/10.22159/ijap.2018v10i4.26795.

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Objective: The aim of the present study was to obtain an optimized formula of meniran (Phyllanthus niruri L.) extract tablets that fulfilled the requirements as a good pharmaceutical preparation based on Indonesian Pharmacopoeia IV and USP XVII.Methods: P. niruri plant was collected and determined at the Laboratory of Plant Taxonomy, Universitas Padjadjaran. First performed phytochemical screening to determine the content of secondary metabolites. Then designed five kinds of tablet formulas of P. niruri extract using a direct compressed method with a variation of concentration of filler. Each

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Sultana, Kishwar. "Formulation of ferrous fumarate (combination) tablets by using a direct-compression method." Indian Journal of Science and Technology 3, no. 9 (2010): 994–1000. http://dx.doi.org/10.17485/ijst/2010/v3i9.10.

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Bhowmik, Debjit, Rishab Bhanot, Darsh Gautam, Parshuram Rai, and K. P. Sampath Kumar. "Formulation and Evaluation of Telmisartan Fast Dissolving Tablets by Direct Compression Method." Research Journal of Pharmaceutical Dosage Forms and Technology 9, no. 3 (2017): 131. http://dx.doi.org/10.5958/0975-4377.2017.00022.2.

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Rosario, Nery L., and Evone S. Ghaly. "Matrices of Water-Soluble Drug Using Natural Polymer and Direct Compression Method." Drug Development and Industrial Pharmacy 28, no. 8 (2002): 975–88. http://dx.doi.org/10.1081/ddc-120006429.

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Sanjiv Kumar Pandey, Jwala Pudasaini, Nedina Parajuli, et al. "Formulation and evaluation of floating tablet of nimesulide by direct compression method." Magna Scientia Advanced Research and Reviews 10, no. 1 (2024): 153–61. http://dx.doi.org/10.30574/msarr.2024.10.1.0008.

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Nimesulide has been used versatile on fever, pain, inflammation, rheumatoid arthritis, tendinitis, thrombophlebitis and trauma. Common drawbacks of conventional tablet dosage forms of nimesulide show an irritant effect on the stomach due to its weakly acidic nature along it has short duration of action leading to poor bioavailability. A Floating drug delivery system for Nimesulide leads to overcoming the problem related to an irritant on the stomach by avoiding direct contact with the mucosa. Thus, this study was designed and performed to formulate and evaluate the floating tablet of Nimesulid

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Королев, И. Д., Е. С. Литвинов, Д. И. Маркин, and Е. А. Рогозин. "A method of direct syntactic transformation of data as a means of minimizing the amount of data on information security events and incidents." МОДЕЛИРОВАНИЕ, ОПТИМИЗАЦИЯ И ИНФОРМАЦИОННЫЕ ТЕХНОЛОГИИ 9, no. 3(34) (2021): 24–25. http://dx.doi.org/10.26102/2310-6018/2021.34.3.024.

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Актуальность исследования обусловлена необходимостью повышения скорости и качества информационного обмена в информационных инфраструктурах, защищаемых средствами центров информационной защиты (security operation centers) в период активного вредоносного воздействия на канал связи, использовании высоконагруженных или низкоскоростных (нестабильных) каналов связи. В связи с этим, данная статья направлена на выявление способа (или метода) компрессии передаваемых данных в режиме реального времени (или с минимальными задержками), работающего с минимальными требованиями к привлекаемым ресурсам и позво

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Zakaria, Ahmed Waad, and Hayder Al-Baghdadi. "Experimental and Numerical Study on CFRP-Confined Square Concrete Compression Members Subjected to Compressive Loading." Journal of Engineering 26, no. 4 (2020): 141–60. http://dx.doi.org/10.31026/j.eng.2020.04.10.

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 Strengthening of the existing structures is an important task that civil engineers continuously face. Compression members, especially columns, being the most important members of any structure, are the most important members to strengthen if the need ever arise. The method of strengthening compression members by direct wrapping by Carbon Fiber Reinforced Polymer (CFRP) was adopted in this research. Since the concrete material is a heterogeneous and complex in behavior, thus, the behavior of the confined compression members subjected to uniaxial stress is investigated by finite element (

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Suraj, kothule. "Formulation Development and Evaluation of Gastroretentive Floating Tablet of Vildagliptin." INTERNATIONAL JOURNAL IN PHARMACEUTICAL SCIENCES 1, no. 1 (2021): 21–30. https://doi.org/10.5281/zenodo.5654051.

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The present study was an attempt to formulate and evaluate a floating tablet of vildagliptin using polymers such as HPMC K4M, Carbopol 934, NaHCO3, and citric acid as gas producers. vildagliptin, an antidiabetic drug with 85% oral bioavailability, short half-life (1.5 hours) and largely associated with an acidic pH, is believed to increase gastric survival and therapeutic efficacy. This can be achieved by making floating pills that stay in the stomach for a long time to release the drug. The tablets are formulated using the direct compression method. The effects of sodium bicarbonate and citri

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Bolmal, Uday, C. K. Pandey, V. Phatarpekar, N. G. Dhople, and Rajkumar Kotha. "Comparative Evaluation of Isoniazid and Rifampicin Dispersible Tablets Prepared by Direct Compression and Sublimation Methods." International Journal of Pharmaceutical Sciences and Nanotechnology 6, no. 4 (2013): 2225–39. http://dx.doi.org/10.37285/ijpsn.2013.6.4.5.

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Dispersible tablets are gaining popularity over conventional tablets due to its increased popularity for administration to pediatric and geriatric patients as it provides quick onset of action and ease of administration. An attempt had been made, to develop dispersible tablet of isoniazid and rifampicin combination by direct compression and sublimation method, to increase the bioavailability of the anti-tubercular agents as well to provide the local delivery in the case of oral tuberculosis. Formulation F1 to F8 (2% and 4% w/w of different superdisintegrants (crospovidone, pregelatinized starc

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Aura Nasyafa, Novita Indira Sari, Lili Sa’adah, Nur Asyifa Ramadhanti, and Tiara Maulida. "Formulasi Dan Evaluasi Sedian Tablet Dengan Metode Kempa Langsung." Jurnal Sains Farmasi Dan Kesehatan 2, no. 2 (2024): 109–13. https://doi.org/10.62379/jfkes.v2i2.1790.

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The objective of this research is to study the formulation and evaluation of tablet preparations using the direct compression method. The method used in this research is a Systematic Literature Review. The findings of the study explain that the direct compression method is an efficient and economical technique in tablet production, especially in the pharmaceutical industry. With the advancement of technology, this method is increasingly used to produce tablets directly from a mixture of active ingredients and excipients without going through granulation processes, whether wet or dry. This proc

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