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Journal articles on the topic 'Direct cortical stimulation'

Author: Grafiati

Published: 5 October 2024

Last updated: 25 July 2025

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1

Foster, Brett L., and Josef Parvizi. "Direct cortical stimulation of human posteromedial cortex." Neurology 88, no. 7 (2017): 685–91. http://dx.doi.org/10.1212/wnl.0000000000003607.

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Background:The posteromedial cortex (PMC) is a collective term for an anatomically heterogeneous area of the brain constituting a core node of the human default mode network (DMN), which is engaged during internally focused subjective cognition such as autobiographical memory.Methods:We explored the effects of causal perturbations of PMC with direct electric brain stimulation (EBS) during presurgical epilepsy monitoring with intracranial EEG electrodes.Results:Data were collected from 885 stimulations in 25 patients implanted with intracranial electrodes across the PMC. While EBS of regions im

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Nitsche, Michael A., Astrid Schauenburg, Nicolas Lang, et al. "Facilitation of Implicit Motor Learning by Weak Transcranial Direct Current Stimulation of the Primary Motor Cortex in the Human." Journal of Cognitive Neuroscience 15, no. 4 (2003): 619–26. http://dx.doi.org/10.1162/089892903321662994.

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Transcranially applied weak direct currents are capable of modulating motor cortical excitability in the human. Anodal stimulation enhances excitability, cathodal stimulation diminishes it. Cortical excitability changes accompany motor learning. Here we show that weak direct currents are capable of improving implicit motor learning in the human. During performance of a serial reaction time task, the primary motor cortex, premotor, or prefrontal cortices were stimulated contralaterally to the performing hand. Anodal stimulation of the primary motor cortex resulted in increased performance, wher

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Maxian, Viorel. "DIRECT CORTICAL STIMULATION IN THE ABLATION OF GLIAL CEREBRAL TUMORS IN THE MOTOR AREAS." Arta Medica 76, no. 3 (2020): 71–75. https://doi.org/10.5281/zenodo.4070041.

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<strong>Objectives.</strong> The genesis of tumors is unknown in our days. Surgery represents an effective treatment of this disorder. According to many studies of brain tumor surgery, a motor deficit rate of 30% has been observed, postoperatively, after surgeries on brain tumors in the motor areas.  The aim of the study was to evaluate the direct cortical stimulation in the surgical treatment of glial brain tumors, in motor areas. <strong>Material and Methods. </strong>The examination group included 35 patients with brain tumors, localized in the parasilvian region. Direct cortical stimu

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Saleem, Yusra, Komal ., and Stephen Riaz. "Transcranial Direct Current Stimulation (TDCS)." International Journal of Endorsing Health Science Research (IJEHSR) 10, no. 4 (2022): 441–45. http://dx.doi.org/10.29052/ijehsr.v10.i4.2022.441-445.

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Transcranial direct current stimulation (TDCS) is a neuromodulatory device that is used for its ability to enhance cognitive and behavioral performance. Human studies suggest that TDCS modulates cortical excitability during stimulation by nonsynaptic changes of the cells, along with evidence that the after-effects of TDCS are driven by synaptic modification. TDCS represents a potential intervention to enhance cognition across clinical populations, including mild cognitive impairment among psychological and neurological disorders. Studies suggest that TDCS might be helpful in treating depressio

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Wong, Pei-Ling, Yea-Ru Yang, Shih-Fong Huang, and Ray-Yau Wang. "Effects of Transcranial Direct Current Stimulation Followed by Treadmill Training on Dual-Task Walking and Cortical Activity in Chronic Stroke: A Double-Blinded Randomized Controlled Trial." Journal of Rehabilitation Medicine 55 (March 21, 2023): jrm00379. http://dx.doi.org/10.2340/jrm.v55.5258.

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Objective: To explore the effects of transcranial direct current stimulation followed by treadmill training on dual-task gait performance and contralesional cortical activity in chronic stroke patients.Methods: Forty-five chronic stroke participants were randomized into 3 groups: a bilateral transcranial direct current stimulation and treadmill training group; a cathodal transcranial direct current stimulation and treadmill training group; and a sham transcranial direct current stimulation and treadmill training group for 50 min per session (20 min transcranial direct current stimulation follo

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Schuh, Lori, and Ivo Drury. "Intraoperative electrocorticography and direct cortical electrical stimulation." Seminars in Anesthesia, Perioperative Medicine and Pain 16, no. 1 (1997): 46–55. http://dx.doi.org/10.1016/s0277-0326(97)80007-4.

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Oishi, M., K. Suzuki, O. Sasaki, et al. "Crossed aphasia elicited by direct cortical stimulation." Neurology 67, no. 7 (2006): 1306–7. http://dx.doi.org/10.1212/01.wnl.0000238468.84401.d4.

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Luders, H. O., I. Derakhshan, M. Oishi, et al. "CROSSED APHASIA ELICITED BY DIRECT CORTICAL STIMULATION." Neurology 68, no. 19 (2007): 1638–40. http://dx.doi.org/10.1212/01.wnl.0000265607.23814.05.

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Sehatpour, Pejman, Devin Adair, Stephanie Rohrig, et al. "Cortical Modulation using Transcranial Direct Current Stimulation." Brain Stimulation 7, no. 2 (2014): e4. http://dx.doi.org/10.1016/j.brs.2014.01.017.

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Sehatpour, Pejman, Devin Adair, Stephanie Rohrig, Joanna DiCostanzo, and Daniel C. Javitt. "Transcranial Direct Current Stimulation Modulates Cortical Networks." Brain Stimulation 10, no. 1 (2017): e7. http://dx.doi.org/10.1016/j.brs.2016.11.040.

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Yaksh, Tony L., Jia-Yi Wang, V. L. W. Go, and Gail J. Harty. "Cortical Vasodilatation Produced by Vasoactive Intestinal Polypeptide (VIP) and by Physiological Stimuli in the Cat." Journal of Cerebral Blood Flow & Metabolism 7, no. 3 (1987): 315–26. http://dx.doi.org/10.1038/jcbfm.1987.69.

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In chloralose-urethanized cats, vasoactive intestinal peptide (VIP), applied by superfusion in steady-state concentration (10−10–10−6 M) onto cortical vessels in situ resulted in a rapid concentration-dependent vasodilatation in vessels that were mildly constricted by prostaglandin F2α (PGF2α) (5 × 10−5 M) or hypocarbia (PaCO2 = 26). The maximum dilatation produced by VIP (10−6 M) was about 60% over baseline in pial arteries and 40% in pial veins. Blockade of local neuronal activity with tetrodotoxin (TTX) (10−5 M) had no effect on the VIP-evoked dilation of pial vessels. Activation of the cor

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Huang, Yuhao (Danny), Sydney Cash, Corey Keller, and Angelique Paulk. "243 Intracranial Theta-burst Stimulation Modulates Cortical Excitability in a Dose and Location-dependent Fashion." Neurosurgery 70, Supplement_1 (2024): 67. http://dx.doi.org/10.1227/neu.0000000000002809_243.

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INTRODUCTION: Direct electrical stimulation is a powerful therapeutic approach to treating a wide range of brain disorders. In particular, theta-burst stimulation (TBS) which delivers electrical pulses in rhythmic bursts of 3-8 Hz to mimic endogenous brain rhythms, has been increasingly used to improve cognitive processes and relieve symptoms of depression. However, how TBS alters underlying neural activity is poorly understood. METHODS: In nine neurosurgical epilepsy subjects undergoing intracranial monitoring, we applied direct cortical TBS at varying stimulation amplitudes and locations (pr

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Krings, Timo, Bradley R. Buchbinder, William E. Butler, et al. "Stereotactic Transcranial Magnetic Stimulation: Correlation with Direct Electrical Cortical Stimulation." Neurosurgery 41, no. 6 (1997): 1319–26. http://dx.doi.org/10.1097/00006123-199712000-00016.

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R.*, Rusina, Barek S., Vaculín S., Azerad J., and Rokyta R. "Cortical stimulation and tooth pulp evoked potentials in rats: A model of direct anti-nociception." Acta Neurobiologiae Experimentalis 70, no. 1 (2010): 47–55. http://dx.doi.org/10.55782/ane-2010-1773.

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While the effect of cortex stimulation on pain control is widely accepted, its physiological basis remains poorly understood. We chose an animal model of pain to study the influence of sensorimotor cortex stimulation on tooth pulp stimulation evoked potentials (TPEPs). Fifteen awake rats implanted with tooth pulp, cerebral cortex, and digastric muscle electrodes were divided into three groups, receiving 60 Hz, 40 Hz and no cortical stimulation, respectively. TPEPs were recorded before, one, three and five hours after continuous stimulation. We observed an inverse relationship between TPEP ampl

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Fregni, Felipe, Paulo S. Boggio, Marcelo C. Santos, et al. "Noninvasive cortical stimulation with transcranial direct current stimulation in Parkinson's disease." Movement Disorders 21, no. 10 (2006): 1693–702. http://dx.doi.org/10.1002/mds.21012.

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Biton, Victor, Miguel E. Fiol, John R. Gates, and Robert E. Maxwell. "Inhibitory Sensory Locus Defined by Direct Cortical Stimulation." Journal of Clinical Neurophysiology 5, no. 4 (1988): 338. http://dx.doi.org/10.1097/00004691-198810000-00040.

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Sehm, Bernhard, Alexander Schäfer, Judy Kipping, et al. "Dynamic modulation of intrinsic functional connectivity by transcranial direct current stimulation." Journal of Neurophysiology 108, no. 12 (2012): 3253–63. http://dx.doi.org/10.1152/jn.00606.2012.

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Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique capable of modulating cortical excitability and thereby influencing behavior and learning. Recent evidence suggests that bilateral tDCS over both primary sensorimotor cortices (SM1) yields more prominent effects on motor performance in both healthy subjects and chronic stroke patients than unilateral tDCS over SM1. To better characterize the underlying neural mechanisms of this effect, we aimed to explore changes in resting-state functional connectivity during both stimulation types. In a randomized sin

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Qi, Xiaofei, Kexin Lyu, Long Meng, et al. "Low-Intensity Ultrasound Causes Direct Excitation of Auditory Cortical Neurons." Neural Plasticity 2021 (April 4, 2021): 1–10. http://dx.doi.org/10.1155/2021/8855055.

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Cochlear implantation is the first-line treatment for severe and profound hearing loss in children and adults. However, deaf patients with cochlear malformations or with cochlear nerve deficiencies are ineligible for cochlear implants. Meanwhile, the limited spatial selectivity and high risk of invasive craniotomy restrict the wide application of auditory brainstem implants. A noninvasive alternative strategy for safe and effective neuronal stimulation is urgently needed to address this issue. Because of its advantage in neural modulation over electrical stimulation, low-intensity ultrasound (

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Noll, Kyle, Priscella Asman, Katherine Connelly, et al. "NCOG-14. INTRAOPERATIVE COGNITIVE-LINGUISTIC MAPPING GUIDED BY VISUALIZATION OF GAMMA BAND MODULATION ELECTROCORTICOGRAMS: PROOF OF CONCEPT IN A PATIENT WITH LEFT TEMPORAL AND OCCIPITAL LOW-GRADE ASTROCYTOMA." Neuro-Oncology 24, Supplement_7 (2022): vii200. http://dx.doi.org/10.1093/neuonc/noac209.767.

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Abstract OBJECTIVE Determine the feasibility and preliminary utility of a novel approach to intraoperative brain mapping guided by visualization of electrocorticography (ECoG) heat maps. METHODS A 39-year-old male with a biopsy-proven left posterior temporal and occipital WHO grade II IDH-mutant astrocytoma underwent awake craniotomy with intraoperative language mapping. Language mapping utilized a dual iPad stimulus presentation system (NeuroMapper) coupled to a portable real-time neural signal processing system capable of both recording cortical activity and delivering direct cortical stimul

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Oda, Nobuhito, Masami Ishii, and Bong-Kyun Kim. "The efficacy of direct motor cortical stimulation for sensori-motor cortical lesions." Clinical Neurology and Neurosurgery 99 (July 1997): S33. http://dx.doi.org/10.1016/s0303-8467(97)81392-3.

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Lee, Hongju, Juyeon Lee, Dahee Jung, Harim Oh, Hwakyoung Shin, and Byungtae Choi. "Neuroprotection of Transcranial Cortical and Peripheral Somatosensory Electrical Stimulation by Modulating a Common Neuronal Death Pathway in Mice with Ischemic Stroke." International Journal of Molecular Sciences 25, no. 14 (2024): 7546. http://dx.doi.org/10.3390/ijms25147546.

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Therapeutic electrical stimulation, such as transcranial cortical stimulation and peripheral somatosensory stimulation, is used to improve motor function in patients with stroke. We hypothesized that these stimulations exert neuroprotective effects during the subacute phase of ischemic stroke by regulating novel common signaling pathways. Male C57BL/6J mouse models of ischemic stroke were treated with high-definition (HD)-transcranial alternating current stimulation (tACS; 20 Hz, 89.1 A/mm2), HD-transcranial direct current stimulation (tDCS; intensity, 55 A/mm2; charge density, 66,000 C/m2), o

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Nitsche, M. A., S. Doemkes, T. Karaköse, et al. "Shaping the Effects of Transcranial Direct Current Stimulation of the Human Motor Cortex." Journal of Neurophysiology 97, no. 4 (2007): 3109–17. http://dx.doi.org/10.1152/jn.01312.2006.

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Transcranial DC stimulation (tDCS) induces stimulation polarity-dependent neuroplastic excitability shifts in the human brain. Because it accomplishes long-lasting effects and its application is simple, it is used increasingly. However, one drawback is its low focality, caused by 1) the large stimulation electrode and 2) the functionally effective reference electrode, which is also situated on the scalp. We aimed to increase the focality of tDCS, which might improve the interpretation of the functional effects of stimulation because it will restrict its effects to more clearly defined cortical

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Ahmed, Zaghloul, and Andrzej Wieraszko. "Trans-spinal direct current enhances corticospinal output and stimulation-evoked release of glutamate analog, D-2,3-3H-aspartic acid." Journal of Applied Physiology 112, no. 9 (2012): 1576–92. http://dx.doi.org/10.1152/japplphysiol.00967.2011.

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Trans-spinal direct current (tsDC) stimulation is a modulator of spinal excitability and can influence cortically elicited muscle contraction in a polarity-dependent fashion. When combined with low-frequency repetitive cortical stimulation, cathodal tsDC [tsDC(−)] produces a long-term facilitation of cortically elicited muscle actions. We investigated the ability of this combined stimulation paradigm to facilitate cortically elicited muscle actions in spinal cord-injured and noninjured animals. The effect of tsDC—applied alone or in combination with repetitive spinal stimulation (rSS) on the r

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Chadaide, Z., S. Arlt, A. Antal, MA Nitsche, N. Lang, and W. Paulus. "Transcranial Direct Current Stimulation Reveals Inhibitory Deficiency In Migraine." Cephalalgia 27, no. 7 (2007): 833–39. http://dx.doi.org/10.1111/j.1468-2982.2007.01337.x.

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The issue of interictal excitability of cortical neurons in migraine patients is controversial: some studies have reported hypo-, others hyperexcitability. The aim of the present study was to observe the dynamics of this basic interictal state by further modulating the excitability level of the visual cortex using transcranial direct current stimulation (tDCS) in migraineurs with and without aura. In healthy subjects anodal tDCS decreases, cathodal stimulation increases transcranial magnetic stimulation (TMS)-elicited phosphene thresholds (PT), which is suggested as a representative value of v

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Cherney, Leora R. "Cortical Stimulation and Aphasia: The State of the Science." Perspectives on Neurophysiology and Neurogenic Speech and Language Disorders 18, no. 1 (2008): 33–39. http://dx.doi.org/10.1044/nnsld18.1.33.

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Abstract Purpose: Biological approaches to aphasia rehabilitation involve procedures aimed to alter brain anatomy and physiology so that language function can be restored. One such approach is the application of electrical stimulation to the cerebral cortex to facilitate brain plasticity and enhance stroke recovery. Method: This article discusses the rationale for the application of cortical stimulation and reviews three different methods of delivering cortical brain stimulation — repetitive transcranial magnetic stimulation (rTMS), transcranial direct current stimulation (tDCS), and epidural

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Adeel, Muhammad, Chun-Ching Chen, Bor-Shing Lin, et al. "Safety of Special Waveform of Transcranial Electrical Stimulation (TES): In Vivo Assessment." International Journal of Molecular Sciences 23, no. 12 (2022): 6850. http://dx.doi.org/10.3390/ijms23126850.

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Intermittent theta burst (iTBS) powered by direct current stimulation (DCS) can safely be applied transcranially to induce neuroplasticity in the human and animal brain cortex. tDCS-iTBS is a special waveform that is used by very few studies, and its safety needs to be confirmed. Therefore, we aimed to evaluate the safety of tDCS-iTBS in an animal model after brain stimulations for 1 h and 4 weeks. Thirty-one Sprague Dawley rats were divided into two groups: (1) short-term stimulation for 1 h/session (sham, low, and high) and (2) long-term for 30 min, 3 sessions/week for 4 weeks (sham and high

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Cohen, L. G., S. Sato, K. Kufta, and M. Hallett. "Attenuation of somatosensory perception by transcranial magnetic stimulation and direct cortical stimulation." Electroencephalography and Clinical Neurophysiology 75 (January 1990): S25—S26. http://dx.doi.org/10.1016/0013-4694(90)91809-4.

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Jacobs, M., A. Premji, and A. J. Nelson. "Plasticity-Inducing TMS Protocols to Investigate Somatosensory Control of Hand Function." Neural Plasticity 2012 (2012): 1–12. http://dx.doi.org/10.1155/2012/350574.

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Hand function depends on sensory feedback to direct an appropriate motor response. There is clear evidence that somatosensory cortices modulate motor behaviour and physiology within primary motor cortex. However, this information is mainly from research in animals and the bridge to human hand control is needed. Emerging evidence in humans supports the notion that somatosensory cortices modulate motor behaviour, physiology and sensory perception. Transcranial magnetic stimulation (TMS) allows for the investigation of primary and higher-order somatosensory cortices and their role in control of h

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Ip, Emily Y., Elisa Roncati Zanier, Amy H. Moore, Stefan M. Lee, and David A. Hovda. "Metabolic, Neurochemical, and Histologic Responses to Vibrissa Motor Cortex Stimulation after Traumatic Brain Injury." Journal of Cerebral Blood Flow & Metabolism 23, no. 8 (2003): 900–910. http://dx.doi.org/10.1097/01.wcb.0000076702.71231.f2.

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During the prolonged metabolic depression after traumatic brain injury (TBI), neurons are less able to respond metabolically to peripheral stimulation. Because this decreased responsiveness has been attributed to circuit dysfunction, the present study examined the metabolic, neurochemical, and histologic responses to direct cortical stimulation after lateral fluid percussion injury (LFPI). This study addressed three specific hypotheses: that neurons, if activated after LFPI, will increase their utilization of glucose even during a period of posttraumatic metabolic depression; that this seconda

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Moliadze, Vera, Georg Fritzsche, and Andrea Antal. "Comparing the Efficacy of Excitatory Transcranial Stimulation Methods Measuring Motor Evoked Potentials." Neural Plasticity 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/837141.

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The common aim of transcranial stimulation methods is the induction or alterations of cortical excitability in a controlled way. Significant effects of each individual stimulation method have been published; however, conclusive direct comparisons of many of these methods are rare. The aim of the present study was to compare the efficacy of three widely applied stimulation methods inducing excitability enhancement in the motor cortex: 1 mA anodal transcranial direct current stimulation (atDCS), intermittent theta burst stimulation (iTBS), and 1 mA transcranial random noise stimulation (tRNS) wi

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Lim, Sung Hyuk, and Min Hwan Jang. "Technical Considerations of Effective Direct Cortical and Subcortical Stimulation." Korean Journal of Clinical Laboratory Science 54, no. 2 (2022): 157–62. http://dx.doi.org/10.15324/kjcls.2022.54.2.157.

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Bialik, Paul Shkurovich. "38. Mapping eloquent cortical areas with direct electrical stimulation." Clinical Neurophysiology 127, no. 9 (2016): e311. http://dx.doi.org/10.1016/j.clinph.2016.05.313.

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Speth, C., J. Speth, and T. Harley. "Transcranial direct current stimulation and cortical indicators of relaxation." Brain Stimulation 8, no. 2 (2015): 405. http://dx.doi.org/10.1016/j.brs.2015.01.290.

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Sun, Yan, Sameer C. Dhamne, Alejandro Carretero‐Guillén, et al. "Drug‐Responsive Inhomogeneous Cortical Modulation by Direct Current Stimulation." Annals of Neurology 88, no. 3 (2020): 489–502. http://dx.doi.org/10.1002/ana.25822.

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Arif, Yasra, Rachel K. Spooner, Alex I. Wiesman, et al. "Prefrontal Multielectrode Transcranial Direct Current Stimulation Modulates Performance and Neural Activity Serving Visuospatial Processing." Cerebral Cortex 30, no. 9 (2020): 4847–57. http://dx.doi.org/10.1093/cercor/bhaa077.

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Abstract The dorsolateral prefrontal cortex (DLPFC) is known to play a critical role in visuospatial attention and processing, but the relative contribution of the left versus right DLPFC remains poorly understood. We applied multielectrode transcranial direct-current stimulation (ME-tDCS) to the left and right DLPFC to investigate its net impact on behavioral performance and population-level neural activity. The primary hypothesis was that significant laterality effects would be observed in regard to behavior and neural oscillations. Twenty-five healthy adults underwent three visits (left, ri

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Jahangiri, Faisal R., Jonathan H. Sherman, Jason Sheehan, et al. "Limiting the Current Density During Localization of the Primary Motor Cortex by Using a Tangential-Radial Cortical Somatosensory Evoked Potentials Model, Direct Electrical Cortical Stimulation, and Electrocorticography." Neurosurgery 69, no. 4 (2011): 893–98. http://dx.doi.org/10.1227/neu.0b013e3182230ac3.

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Abstract BACKGROUND: Traditionally, the dual-radial model, which requires high cortical stimulation intensities and may evoke intraoperative seizures, is used for mapping during resection of lesions within or near the central sulcus. OBJECTIVE: To examine the potential utility of using the multimodal tangential-radial triphasic model, which may increase the accuracy and reliability of cortical mapping at lower stimulation intensities. METHODS: We performed a retrospective review of intracranial neuromonitoring cases at the University of Virginia. The tangential-radial triphasic model used dire

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Alagapan, Sankaraleengam, Stephen L. Schmidt, Jérémie Lefebvre, Eldad Hadar, Hae Won Shin, and Flavio Frӧhlich. "Modulation of Cortical Oscillations by Low-Frequency Direct Cortical Stimulation Is State-Dependent." PLOS Biology 14, no. 3 (2016): e1002424. http://dx.doi.org/10.1371/journal.pbio.1002424.

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Matsumoto, Riki, Masako Kinoshita, Junya Taki, et al. "In Vivo Epileptogenicity of Focal Cortical Dysplasia: A Direct Cortical Paired Stimulation Study." Epilepsia 46, no. 11 (2005): 1744–49. http://dx.doi.org/10.1111/j.1528-1167.2005.00284.x.

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Picht, Thomas, Sven Mularski, Bjoern Kuehn, Peter Vajkoczy, Theodoros Kombos, and Olaf Suess. "Navigated Transcranial Magnetic Stimulation for Preoperative Functional Diagnostics in Brain Tumor Surgery." Operative Neurosurgery 65, suppl_6 (2009): ons93—ons99. http://dx.doi.org/10.1227/01.neu.0000348009.22750.59.

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Abstract Objective: Transcranial magnetic stimulation (TMS) is a noninvasive method for analyzing cortical function. To utilize TMS for presurgical functional diagnostics, the magnetic impulse must be precisely targeted by stereotactically positioning the coil. The aim of this study was to evaluate the usefulness of TMS for operation planning when combined with a sensor-based electromagnetic navigation system (nTMS). Methods: Preoperative functional mapping with nTMS was performed in 10 patients with rolandic tumors. Intraoperative mapping was performed with the “gold standard” of direct corti

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Kunori, Nobuo, and Ichiro Takashima. "Cortical direct current stimulation improves signal transmission between the motor cortices of rats." Neuroscience Letters 741 (January 2021): 135492. http://dx.doi.org/10.1016/j.neulet.2020.135492.

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Loizon, Marine, Philippe Ryvlin, Benoit Chatard, et al. "Transient hypoxemia induced by cortical electrical stimulation." Neurology 94, no. 22 (2020): e2323-e2336. http://dx.doi.org/10.1212/wnl.0000000000009497.

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ObjectiveTo identify which cortical regions are associated with direct electrical stimulation (DES)–induced alteration of breathing significant enough to impair pulse oximetry (SpO2).MethodsEvolution of SpO2 after 1,352 DES was analyzed in 75 patients with refractory focal epilepsy who underwent stereo-EEG recordings. For each DES, we assessed the change in SpO2 from 30 seconds prior to DES onset to 120 seconds following the end of the DES. The primary outcome was occurrence of stimulation-induced transient hypoxemia as defined by decrease of SpO2 ≥5% within 60 seconds after stimulation onset

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Fazaila Ehsaan, Nazia Mumtaz, and Ghulam Saqulain. "Novel therapeutic techniques for post stroke aphasia: a narrative review." Journal of the Pakistan Medical Association 72, no. 01 (2022): 121. http://dx.doi.org/10.47391/jpma.2277.

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Aphasia, a language disorder, results from stroke involving cortical and subcortical structures. Aphasia lacks effective standardized treatment. Neuroimaging and behavioral research indicate that some interventions promote neuroplasticity. Research has suggested that noninvasive brain stimulation may be effective causing functional reorganization of language areas between both hemispheres. This reorganization evolves from different researches exploring novel procedures including transcranial magnetic stimulation and intracranial direct current stimulation, which may modulate cortical activity

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Volf, Nadia. "Somatosensory Evoked Potentials in the Investigation of Auricular Acupuncture Points." Acupuncture in Medicine 18, no. 1 (2000): 2–9. http://dx.doi.org/10.1136/aim.18.1.2.

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A preliminary study correlating the wrist and gall bladder body areas with their auricular acupuncture points, through recording the somatosensory evoked potentials (SEP) at the corresponding brain localisation, showed that stimulation of the “Wrist” auricular point activates the primary cortical somatosensory area of the upper extremity on the contralateral hemisphere in a similar way to direct median nerve stimulation. A “placebo” point 5 to 8mm from the “Wrist” auricular point was used as a control: no activation in the brain area was observed. In patients with post-stroke hemiplegia, SEP t

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Karakis, Ioannis, Beth A. Leeman-Markowski, Catherine L. Leveroni, et al. "Intra-stimulation discharges: An overlooked cortical electrographic entity triggered by direct electrical stimulation." Clinical Neurophysiology 126, no. 5 (2015): 882–88. http://dx.doi.org/10.1016/j.clinph.2014.08.011.

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Weaver, Kurt E., David J. Caldwell, Jeneva A. Cronin, et al. "Concurrent Deep Brain Stimulation Reduces the Direct Cortical Stimulation Necessary for Motor Output." Movement Disorders 35, no. 12 (2020): 2348–53. http://dx.doi.org/10.1002/mds.28255.

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Gomez-Tames, Jose, Akimasa Hirata, Manabu Tamura, and Yoshihiro Muragaki. "Corticomotoneuronal Model for Intraoperative Neurophysiological Monitoring During Direct Brain Stimulation." International Journal of Neural Systems 29, no. 01 (2019): 1850026. http://dx.doi.org/10.1142/s0129065718500260.

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Intraoperative neurophysiological monitoring during brain surgery uses direct cortical stimulation to map the motor cortex by recording muscle activity induced by the excitation of alpha motor neurons (MNs). Computational models have been used to understand local brain stimulation. However, a computational model revealing the stimulation process from the cortex to MNs has not yet been proposed. Thus, the aim of the current study was to develop a corticomotoneuronal (CMN) model to investigate intraoperative stimulation during surgery. The CMN combined the following three processes into one syst

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Pross, Benjamin, Patrick Schulz, Duygu Güler, et al. "S192. EFFECTS OF NICOTINE INTAKE ON NEUROPLASTICITY IN SMOKING AND NON-SMOKING PATIENTS WITH SCHIZOPHRENIA." Schizophrenia Bulletin 46, Supplement_1 (2020): S111—S112. http://dx.doi.org/10.1093/schbul/sbaa031.258.

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Abstract Background Cortical plasticity – the ability to reorganize synaptic connections and adapt to environmental changes – appears to be impaired in schizophrenia patients. Results suggest the dysfunctional plasticity to be a key pathophysiological mechanism. Different non-invasive brain stimulation (NIBS) techniques have been used to modulate and induce cortical plasticity. In healthy subjects, nicotine was shown to play an important role in plasticity induction and is capable to alter cortical excitability and plasticity, induced by NIBS techniques. Our goal was to investigate the promisi

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La Rocca, Marianna, Livio Clemente, Eleonora Gentile, Katia Ricci, Marianna Delussi, and Marina de Tommaso. "Effect of Single Session of Anodal M1 Transcranial Direct Current Stimulation—TDCS—On Cortical Hemodynamic Activity: A Pilot Study in Fibromyalgia." Brain Sciences 12, no. 11 (2022): 1569. http://dx.doi.org/10.3390/brainsci12111569.

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Transcranial direct current stimulation (TDCS) on the primary motor cortex (M1) has been reported to be effective in fibromyalgia (FM). Our previous works have shown hypometabolism of motor networks in FM using Functional Near Infrared Spectroscopy (fNIRS), which could contribute to pain symptoms. To investigate if a single Transcranial Direct Current Stimulation (TDCS) session can restore the reduced metabolism expected in FM patients, we compared metabolic activity in FM patients and controls during a finger-tapping task in basal condition, sham condition, and under anodal TDCS on M1. During

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Lang, Nicolas, Michael A. Nitsche, Michele Dileone, et al. "Transcranial direct current stimulation effects on I-wave activity in humans." Journal of Neurophysiology 105, no. 6 (2011): 2802–10. http://dx.doi.org/10.1152/jn.00617.2010.

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Transcranial direct current stimulation (tDCS) of the human cerebral cortex modulates cortical excitability noninvasively in a polarity-specific manner: anodal tDCS leads to lasting facilitation and cathodal tDCS to inhibition of motor cortex excitability. To further elucidate the underlying physiological mechanisms, we recorded corticospinal volleys evoked by single-pulse transcranial magnetic stimulation of the primary motor cortex before and after a 5-min period of anodal or cathodal tDCS in eight conscious patients who had electrodes implanted in the cervical epidural space for the control

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De Doncker, William, Sasha Ondobaka, and Annapoorna Kuppuswamy. "Effect of transcranial direct current stimulation on post-stroke fatigue." Journal of Neurology 268, no. 8 (2021): 2831–42. http://dx.doi.org/10.1007/s00415-021-10442-8.

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Abstract Background Fatigue is one of the most commonly reported symptoms post-stroke, which has a severe impact on the quality of life. Post-stroke fatigue is associated with reduced motor cortical excitability, specifically of the affected hemisphere. Objective The aim of this exploratory study was to assess whether fatigue symptoms can be reduced by increasing cortical excitability using anodal transcranial direct current stimulation (tDCS). Methods In this sham-controlled, double-blind intervention study, tDCS was applied bilaterally over the primary motor cortex in a single session in thi

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