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Journal articles on the topic 'Disease precedence'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Seo, Jangwon, Junhee Seok, and Yoojoong Kim. "Prioritizing Disease Diagnosis in Neonatal Cohorts through Multivariate Survival Analysis: A Nonparametric Bayesian Approach." Healthcare 12, no. 9 (2024): 939. http://dx.doi.org/10.3390/healthcare12090939.

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Understanding the intricate relationships between diseases is critical for both prevention and recovery. However, there is a lack of suitable methodologies for exploring the precedence relationships within multiple censored time-to-event data, resulting in decreased analytical accuracy. This study introduces the Censored Event Precedence Analysis (CEPA), which is a nonparametric Bayesian approach suitable for understanding the precedence relationships in censored multivariate events. CEPA aims to analyze the precedence relationships between events to predict subsequent occurrences effectively.

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Kloepper, Joseph W., Sadik Tuzun, Geoffrey W. Zehnder, and Gang Wei. "Multiple Disease Protection by Rhizobacteria that Induce Systemic Resistance—Historical Precedence." Phytopathology® 87, no. 2 (1997): 136–37. http://dx.doi.org/10.1094/phyto.1997.87.2.136.

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González, G. Hortensia, Oscar Infante, Paola Martínez-García, et al. "Dynamical interaction between heart rate and blood pressure of end-stage renal disease patients evaluated by cross recurrence plot diagonal analysis." Journal of Applied Physiology 128, no. 1 (2020): 189–96. http://dx.doi.org/10.1152/japplphysiol.00364.2019.

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The assessment of spontaneous variability of blood pressure and heart rate is based on specific physiological hypotheses about dynamic features, for example, the baroreflex modulation of heart rate over time in daily life. Usually, arterial baroreflex control of heart rate is explored without delays between blood pressure and heart rate data points, within a narrow range of values, excluding the analysis of saturation regions or low-threshold changes. In this work, we examine the dynamic interactions between systolic blood pressure (SBP) and interbeat interval (IBI), in 15-min length time seri

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Park, Junhee, Kyungdo Han, Kyuna Lee, Yoosoo Chang, and Dong Wook Shin. "Risk of Cardiovascular Disease According to the Precedence Relationship Between Hypertension and Diabetes Mellitus." Healthcare 13, no. 7 (2025): 796. https://doi.org/10.3390/healthcare13070796.

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Background/Objectives: Cardiovascular disease (CVD) risk may be based on the sequence of hypertension (HTN) and diabetes mellitus (DM) occurrence since the pathophysiological mechanisms might not be the same. The present study examined the risk of CVD according to the precedent relationship between HTN and DM. Methods: Participants with both HTN and DM in a national health screening program in 2015–2016 were divided into two groups based on the order of HTN and DM occurrence: ‘HTN → DM’ and ‘DM → HTN’. The primary outcomes were newly diagnosed myocardial infarction (MI) and ischemic stroke bas

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Karwańska, Aleksandra, Aleksandra Kulbat, Kamila Świercz, et al. "The impact of physical activity, diet and stress on acne vulgaris. Pathogenesis and therapeutic procedures." Journal of Education, Health and Sport 13, no. 3 (2023): 18–23. http://dx.doi.org/10.12775/jehs.2023.13.03.002.

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Introduction Acne vulgaris is the most common skin disease that affects the majority of the population. Concepts on the pathogenesis of this disease have been changing over the years, as evidenced by the current indication of the precedence of inflammatory or immunological processes over disorders of keratinization of the outlets of hair and sebaceous units during the formation of acne lesions. Due to the complexity of the etiopathogenesis of acne vulgaris, the selection of appropriate therapeutic management is sometimes complicated. In addition, the process of treating the disease is multifac

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Park, Junhee, Kyungdo Han, Kyuna Lee, Yoosoo Chang, and Dong Wook Shin. "RISK OF CARDIOVASCULAR DISEASE ACCORDING TO THE PRECEDENCE RELATIONSHIP BETWEEN HYPERTENSION AND DIABETES MELLITUS." Journal of Hypertension 43, Suppl 1 (2025): e167. https://doi.org/10.1097/01.hjh.0001116884.03863.47.

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Pierce, Jenny L. "Laryngeal Manifestations of Autoimmune Diseases." Perspectives of the ASHA Special Interest Groups 5, no. 2 (2020): 439–56. http://dx.doi.org/10.1044/2020_persp-19-00168.

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Purpose This review article provides an overview of autoimmune diseases and their effects on voice and laryngeal function. Method A literature review was conducted in PubMed. Combinations of the following keywords were used: “autoimmune disease and upper airway,” “larynx,” “cough,” “voice,” “dysphonia,” and “dyspnea.” Precedence was given to articles published in the past 10 years due to recent advances in this area and to review articles. Ultimately, 115 articles were included for review. Results Approximately 81 autoimmune diseases exist, with 18 of those highlighted in the literature as hav

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Boland, Philip J., Harshinder Singh, and Bojan Cukic. "The stochastic precedence ordering with applications in sampling and testing." Journal of Applied Probability 41, no. 1 (2004): 73–82. http://dx.doi.org/10.1239/jap/1077134668.

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Stratified and simple random sampling (or testing) are two common methods used to investigate the number or proportion of items in a population with a particular attribute. Although it is known that cost factors and information about the strata in the population are often crucial in deciding whether to use stratified or simple random sampling in a given situation, the stochastic precedence ordering for random variables can also provide the basis for an interesting criteria under which these methods may be compared. It may be particularly relevant when we are trying to find as many special item

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Boland, Philip J., Harshinder Singh, and Bojan Cukic. "The stochastic precedence ordering with applications in sampling and testing." Journal of Applied Probability 41, no. 01 (2004): 73–82. http://dx.doi.org/10.1017/s0021900200014042.

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Stratified and simple random sampling (or testing) are two common methods used to investigate the number or proportion of items in a population with a particular attribute. Although it is known that cost factors and information about the strata in the population are often crucial in deciding whether to use stratified or simple random sampling in a given situation, the stochastic precedence ordering for random variables can also provide the basis for an interesting criteria under which these methods may be compared. It may be particularly relevant when we are trying to find as many special item

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Johnson, M., J. Lai, M. Corona, and G. Lupas. "C-07 Global Precedence: Examining Contributing Effects of Age and Cognitive Functioning." Archives of Clinical Neuropsychology 34, no. 6 (2019): 1034. http://dx.doi.org/10.1093/arclin/acz034.169.

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Abstract Objective Global precedence (GP) is an individual’s ability to readily identify global (gestalt) features when both global and local (internal) details are presented. Prior research shows that both age and neurodegenerative diseases, such as Alzheimer’s, affect GP. The goal of the current study is to examine differences in GP between individuals with early-onset Alzheimer’s disease (EOAD; before age 65) and healthy controls (HC). Method Fourteen EOAD patients and 6 HC’s recruited from Behavioral Neurology at an academic medical center were included in the current analysis. EOAD partic

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Bajwa, Muhammad Naseer, Kaoru Muta, Muhammad Imran Malik, et al. "Computer-Aided Diagnosis of Skin Diseases Using Deep Neural Networks." Applied Sciences 10, no. 7 (2020): 2488. http://dx.doi.org/10.3390/app10072488.

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Propensity of skin diseases to manifest in a variety of forms, lack and maldistribution of qualified dermatologists, and exigency of timely and accurate diagnosis call for automated Computer-Aided Diagnosis (CAD). This study aims at extending previous works on CAD for dermatology by exploring the potential of Deep Learning to classify hundreds of skin diseases, improving classification performance, and utilizing disease taxonomy. We trained state-of-the-art Deep Neural Networks on two of the largest publicly available skin image datasets, namely DermNet and ISIC Archive, and also leveraged dis

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Togashi, Katsumi, and Hiroyuki Sugimoto. "Copulation Duration and Sperm Precedence with Reference to Larval Diapause Induction in Monochamus alternatus Hope (Coleoptera: Cerambycidae)." Insects 15, no. 4 (2024): 255. http://dx.doi.org/10.3390/insects15040255.

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Adults of the pine sawyer Monochamus alternatus are the primary vector of Bursaphelenchus xylophilus, the causative agent of pine wilt disease. A sawyer subspecies in Taiwan (abbreviated ‘T’) has two generations a year (bivoltinism) due to facultative diapause, whereas another subspecies in Japan (abbreviated ‘J’) has a one- or two-year life cycle due to obligate diapause. T, with two infection periods a year, will cause more severe disease epidemics than J if it is introduced into Japan. Inter-subspecies hybridization may inhibit the expression of bivoltinism because many F1 hybrids induce di

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Weston, Erica, and Niharika Mehta. "Moyamoya disease in pregnancy and delivery planning: A case series and literature review." Obstetric Medicine 9, no. 4 (2016): 177–80. http://dx.doi.org/10.1177/1753495x16653548.

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Moyamoya disease is a rare condition characterized by stenosis or occlusion of the intracranial internal carotid arteries leading to the development of fragile collateral vessels. Disruption of these vessels can lead to both ischemic and hemorrhagic strokes. As such, these patients are sensitive to changes in intracranial pressure and pose a challenge in pregnancy and delivery planning. Two cases of a parturients with moyamoya disease are presented, and the literature regarding safe method of delivery in similar patients is reviewed. The available evidence suggests that adequate anesthesia, an

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Abdelaal, Ahmed, Kelvin Ng, and Kelsie Ou. "Over-the-Counter Statins." Meducator 1, no. 30 (2018): 13–14. http://dx.doi.org/10.15173/m.v1i30.1881.

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One in four Canadians over the age of 20 are at a significant risk of developing cardiovascular disease. Despite their proven efficacy as a lipid-loweing therapy for patients at risk, statins continue to be under-prescribed and underused. Proponents of over-the-counter statins argue that increased accessibility will improve usage and lighten the economic burden of cardiovascular diseases. Furthermore, statins have proven to be clinically effective at low doses. Despite these potential benefits, statins should not be approved as over-the-counter drugs as they are accompanied by greater risks of

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Renner, Andreas. "The Transfer of Medical Charlatanism to Eighteenth-Century Russia." East Central Europe 40, no. 3 (2013): 245–67. http://dx.doi.org/10.1163/18763308-04003004.

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This article examines one case study of medical charlatanism from eighteenth-century Russia in its political, social, and ideological dimensions. Quackery is seen as a by-product of “westernization”—the counterpart to European-style medicine institutionalized from above. The legal notion of charlatanism remained irrelevant for the majority of the population, but it was pivotal for the professional identity of physicians. The struggle against charlatanism was a symbolic struggle that confirmed the precedence of official physicians concerning all questions of health and disease. Though the gover

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Shweta Dadarao Parwe, Milind Abhimanyu Nisargandha, and Rishikesh Thakre. "Role of convalescent plasma therapy in new Coronavirus disease (nCOVID-19): A review." International Journal of Research in Pharmaceutical Sciences 11, SPL1 (2020): 546–49. http://dx.doi.org/10.26452/ijrps.v11ispl1.2846.

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Hitherto, there is no proper line of treatment for the new (nCOVID19). The development of unique antiviral drugs has taken precedence. Therapeutic antibodies () will be a significantly beneficial agent against nCOVID-19. Here the host immune responses to new discussed in this review provide strategy and further treatment and understanding of clinical interventions against nCOVID-19. Plasma therapy uses the antibodies found in the blood of people recovering (or convalesced) from an infection to treat infected patients. When an infection occurs, the body begins producing proteins specially made

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Samant, Sadhana A., Vinodkumar B. Pillai, and Mahesh P. Gupta. "Cellular mechanisms promoting cachexia and how they are opposed by sirtuins." Canadian Journal of Physiology and Pharmacology 97, no. 4 (2019): 235–45. http://dx.doi.org/10.1139/cjpp-2018-0479.

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Many chronic diseases are associated with unintentional loss of body weight, which is termed “cachexia”. Cachexia is a complex multifactorial syndrome associated with the underlying primary disease, and characterized by loss of skeletal muscle with or without loss of fat tissue. Patients with cachexia face dire symptoms like dyspnea, fatigue, edema, exercise intolerance, and low responsiveness to medical therapy, which worsen quality of life. Because cachexia is not a stand-alone disorder, treating primary disease — such as cancer — takes precedence for the physician, and it remains mostly a n

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Konkor, Irenius, and Vincent Z. Kuuire. "Epidemiologic transition and the double burden of disease in Ghana: What do we know at the neighborhood level?" PLOS ONE 18, no. 2 (2023): e0281639. http://dx.doi.org/10.1371/journal.pone.0281639.

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Many developing countries including Ghana are currently experiencing dual disease burdens emerging from an unprecedented risk overlap that drive their epidemiological transitions. Yet, siloed and disintegrated approaches continue to take precedence in health research and policy programs that drive competition for limited resources to address competing health problems. The objective of this study was to offer empirical evidence in support of a cogent argument for an integrated framework for the study and management of infectious and chronic health conditions in Ghana. We did so by examining the

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YUKI, NOBUHIRO. "Immunity neurologic disease. Peripheral nerve disease. Mechanism of pathogenesis and treatment of the Guillain-Barre syndrome. Precedence of the Campylobacter jejuni enteritis and antiganglioside antibody." Nihon Naika Gakkai Zasshi 87, no. 4 (1998): 612–16. http://dx.doi.org/10.2169/naika.87.612.

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Ha, Eun-Ho. "Experience of the COVID-19 Pandemic among Middle-Aged Individuals in the South Korean Community: Q Methodological Study." Korean Journal of Adult Nursing 37, no. 2 (2025): 125–39. https://doi.org/10.7475/kjan.2025.0114.

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Purpose: The subjective experiences of middle-aged individuals during the coronavirus disease 2019 (COVID-19) pandemic play a pivotal role in fostering resilience for reintegration into normal life post-pandemic and preparing for potential future infectious disease outbreaks. This study aimed to explore the experiences of middle-aged individuals during the COVID-19 pandemic using the Q methodology. Methods: Forty-six middle-aged individuals from 10 cities in South Korea participated in this study. The participants arranged and ranked 39 Q statements describing their experiences with the COVID-

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Mishra, Arunkumar, and Santosh Chavhan. "Role of Vega-Vidharana as one of the Vyadhi-Hetu in Ayurveda: A Critical Review." International Journal of Diagnostics And Research 1, no. 3 (2024): 7–12. https://doi.org/10.5281/zenodo.10972543.

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According to Charaka Samhita, Swasthasya Swasthya Rakshana (restoration of health of a healthy individual) and Aaturasya Vikara-Prashamana (treatment of disease in ill patients) are the aims of Ayurveda. Swasthya-Rakshana has been given precedence over Vikara-Prashamana. Vega Avidharana is one of the important aspects of Swasthya-Rakshana which is explained in all three major treatises of Ayurveda. Adharaneeya Vega are those natural urges in the body that should not be suppressed or avoided, like the natural urges to expel Mootra, Pureesha, Shukra, etc. When Vega are forcibly suppressed, it le

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Hujoel, P. "Dietary Carbohydrates and Dental-Systemic Diseases." Journal of Dental Research 88, no. 6 (2009): 490–502. http://dx.doi.org/10.1177/0022034509337700.

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Two contradictory hypotheses on the role of dietary carbohydrates in health and disease shape how dental-systemic associations are regarded. On one side, Cleave and Yudkin postulated that excessive dietary fermentable carbohydrate intake led—in the absence of dental interventions such as fluorides— first to dental diseases and then to systemic diseases. Under this hypothesis, dental and systemic diseases shared—as a common cause—a diet of excess fermentable carbohydrates. Dental diseases were regarded as an alarm bell for future systemic diseases, and restricting carbohydrate intake prevented

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Nanda, Chandi Prasad. "Disciplining a ‘Pathological Province’? Orissa, Smallpox and Colonial Order." Indian Historical Review 48, no. 1 (2021): 23–42. http://dx.doi.org/10.1177/03769836211009653.

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A massive corpus of historical scholarship has been produced in the last few decades exploring specificities underlying the triad of disease, health and medicine. The present work explores the linkages between medical knowledge and colonial power drawing resources from the medical archive. The focus of this essay pertains to the study of disease and medicine in relation to their extent of influence on colonial policy and the colonising process and on those who were colonised in the context of a specific locality or a region. It seeks to delineate the career of vaccination as it shaped up throu

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Battegay, Manuel, Ursula Fluckiger, Bernard Hirschel, and Hansjakob Furrer. "Late Presentation of HIV-Infected Individuals." Antiviral Therapy 12, no. 6 (2007): 841–51. http://dx.doi.org/10.1177/135965350701200612.

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Late presentation remains a major concern despite the dramatically improved prognosis realized by ART. We define a first presentation for HIV care during the course of HIV infection as ‘late’ if an AIDS-defining opportunistic disease is apparent, or if CD4+ T-cells are <200/μl. In the Western world, approximately 10 and 30% of HIV-infected individuals still present with CD4+ T-cells <50 and <200/μl, respectively; estimates are substantially higher for developing countries. Diagnosis and treatment of opportunistic diseases and intense supportive in-hospital care take precedence over AR

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Smith, Brendan J., John A. Kirkegaard, and Geoff N. Howe. "Impacts of Brassica break-crops on soil biology and yield of following wheat crops." Australian Journal of Agricultural Research 55, no. 1 (2004): 1. http://dx.doi.org/10.1071/ar03104.

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Biofumigation refers to the allelopathic effects of brassicas on non-desirable soil organisms in a rotation cropping system. These effects are additional to non-hosting of root diseases, responsible for much of the break-crop effect observed in a following cereal crop. We investigated the biofumigation impacts of canola on take-all disease and rhizosphere microorganisms of following wheat crops. The biofumigation potential of the canola was tested by comparing effects of Brassica and non-Brassica break-crops and by using canola varieties with differing levels of root glucosinolates, the precur

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Gutiérrez-Arnal, Josep, and Clara Marín. "The Latent Threat in Wild Birds: Clostridium botulinum." Veterinary Sciences 11, no. 1 (2024): 36. http://dx.doi.org/10.3390/vetsci11010036.

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Avian botulism caused by Clostridium botulinum emerged in 1910, affecting birds across North America, leading to severe outbreaks exacerbated by climate change, decreasing water levels, and inadequate wastewater management. While deadly for birds, its epidemiological impact on humans and other animals remains limited. Despite its significance, understanding and controlling the disease remain challenging. This review delves into the pathogen’s epidemiology in wild bird populations, exploring the transmission, pathogenicity, clinical symptoms, diagnosis and treatment. The disease’s growing conce

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Zvezdin, Biljana, Senka Milutinov, Ivana Tanaskovic, et al. "The frequency of sensitization to inhalatory allergens and concomitant rhinitis in asthmatic patients." Vojnosanitetski pregled 68, no. 4 (2011): 309–13. http://dx.doi.org/10.2298/vsp1104309z.

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Background/Aim. Asthma is one of the most common chronic pulmonary diseases. The number of asthmatics has been continuously increasing all over the world. Depending on its causing agent, asthma is classified as allergic and nonallergic. Asthma is often associated with other allergic diseases, and it is most commonly preceded by the symptoms of rhinitis. The aim of this study was to establish the type and frequency of allergic sensitization to inhalatory allergens, frequency of concomitant rhinitis, gender and age-related distribution of asthma, and the presence of some risk factors in patients

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Canete, Jonathan James O. "The social paradox of COVID-19 pandemic: the duality of socialization and the value of fraternal charity." Journal of Public Health 43, no. 2 (2021): e413-e414. http://dx.doi.org/10.1093/pubmed/fdab114.

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Abstract Government across all nations had promulgated precautionary measures in controlling the wide spread of the disease. One that takes precedence is the practice of community quarantine where people are mandated to stay at home and avoid going outside if is not utterly necessary. This mandate caused a lot of catastrophic outcomes in the socio-economic condition and mental health of many. Many people are in psychological and existential despair for the loss of their jobs and the isolation that they are experiencing. However, in the midst of this undesirable condition, the natural tendency

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Patel, Geetika M., Upendra Sharma, Sudhir Kumar Gupta, and M. Mohanan. "Examining medical urgent and patient precedence within the telemedicine landscape with its infrastructure and policies: A comprehensive review." Multidisciplinary Reviews 6 (January 30, 2024): 2023ss017. http://dx.doi.org/10.31893/multirev.2023ss017.

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Medical facilities are confronted with grave issues, including a population that is aging and a physician shortage. In an effort to address these issues, telehealth and remote health monitoring systems (RHMS) aim to reduce hospital visits by a small amount. RHMS lessens the workload for primary care patients and enhances inter-unit communication, which lessens the strain on emergency rooms. Due to significant advancements in mobile information transfer and processing of signal technologies, some healthcare researchers have made efforts to employ RHMS in place of hospital visits to provide tria

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Sahoo, Susrita, Swati Mohapatra, Swayam prava Dalai, Namrata Misra, and Mrutyunjay Suar. "Effect of Probiotics on Host-Microbial Crosstalk: A Review on Strategies to Combat Diversified Strain of Coronavirus." Encyclopedia 2, no. 2 (2022): 1138–53. http://dx.doi.org/10.3390/encyclopedia2020076.

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The scare of the ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), does not seem to fade away, while there is a constant emergence of novel deadly variants including Alpha, Beta, Gamma, Delta and Omicron. Until now, it has claimed approximately 276,436,619 infections, and the number of deaths surpluses to 5,374,744 all over the world. While saving the life has been a priority during the ongoing SARS-CoV-2 pandemic, the post-infection healing and getting back to normalcy has been undermined. Improving general health

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Choi, Won Suk, Yeonhee Sung, Jimin Kim, et al. "Prioritization of Vaccines for Introduction in the National Immunization Program in the Republic of Korea." Vaccines 12, no. 8 (2024): 886. http://dx.doi.org/10.3390/vaccines12080886.

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This study presents a framework for determining the prioritization of vaccine introduction in the National Immunization Program (NIP) of the Republic of Korea, with a focus on case examples assessed in 2021 and 2023. We describe the predefined criteria for evaluating the prioritization of vaccines in the NIP and the established process in the Republic of Korea. These criteria included disease characteristics, vaccine characteristics, rationality and efficiency of resource allocation, and the acceptance of immunization. The process of prioritizing NIP introduction involved several sequential st

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Oluwole, Oluwafemi G. "Important Guide for Natural Compounds Inclusion in Precision Medicine." OBM Genetics 08, no. 04 (2024): 1–8. https://doi.org/10.21926/obm.genet.2404273.

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Precision medicine describes the definition of disease at a higher resolution by genomic and other technologies to enable more precise targeting of disease subgroups with new therapies. Preventative or therapeutic interventions can be developed with the knowledge of how a compound acts safely in the body to target receptors and produce the desirable effect. With the completion of the Human Genome Project in 2003 and the rapid increase in sequencing and bioinformatics tools, obtaining information about a person's genome is becoming more accessible. To make use of genetic information in precisio

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Almutairi, Muneer, Sami AlShammari, and Fahad Albassam. "Idiopathic Basal Ganglia Calcifications in a Patient with Pediatric Onset Multiple Sclerosis." SVOA Neurology 5, no. 4 (2024): 149–53. http://dx.doi.org/10.58624/svoane.2024.05.0142.

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Idiopathic Basal ganglia calcification, also known as Fahr’s Disease, has been associated with multiple etiologies. There have been case reports of basal ganglia calcifications in a number of patients with multiple sclerosis [MS]. Earlier hypothesis suggested the co-occurrence to be more than coincidental and might indicate an underlying overlapping pathophysiology of mitochondrial dysfunction. However further studies had failed to show higher prevalence of deep grey matter calcifications in MS individuals compared to healthy controls. Multiple sclerosis is known commonly to have a higher rate

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yarlagadda, Uthpala, and Vaishali V. Dolas. "HOMOEOPATHIC PREPARATION OF LYCOPODIUM CLAVATUM EMPHASIZING THE IMPORTANCE OF MENTAL SYMPTOMS ON DIFFERENT DISEASES - A SYSTEMATIC REVIEW." Journal of Nonlinear Analysis and Optimization 15, no. 1 (2024): 134–41. https://doi.org/10.5281/zenodo.10720375.

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ABSTRACTBackground: The mental state reflects the essence of an individual and holds utmost importance in understanding the patient. It is believed that illnesses initially manifest on the mental plane before any physical changes occur. According to the principles of Hahnemann and Kent, mental and emotional symptoms take precedence over physical symptoms. Lycopodium being one of deep acting Homoeopathic medicine, it has great efficacy in various diseases. Aim and objective: This review aims to explore the significance of mental symptoms and evaluate the effectiveness o

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Glisic, Branislava, Silvija Stevic-Carevic, Gorica Ristic, and Jelena Dedovic. "Cogan’s syndrome: A case series." Vojnosanitetski pregled 75, no. 11 (2018): 1128–33. http://dx.doi.org/10.2298/vsp161212001g.

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Introduction. Cogan?s syndrome is a rare variable vessel vasculitis. It can be typical and atypical. Basis of the treatment comprises glucocorticoids, and in patients with systemic manifestations, immunosuppressive drugs. Case report. We wanted to present the experience of the Clinic for Rheumatology and Clinical Immunology of the Military Medical Academy, Belgrade, in diagnosing and treating patients suffering from Cogan?s syndrome. The analysis included 7 patients. Patients? demographic characteristics, disease manifestations, course of the disease, applied treatment and treatment outcome we

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Salim, Binsha, and Madhuri Devi N. "DIABETES INDUCED MICROALBUMINURIA - A CRITICAL REVIEW." November 2020 08, no. 11 (2020): 5137–40. http://dx.doi.org/10.46607/iamj2808112020.

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Microalbuminuria is a marker and a risk factor of diabetic renal complications commences its role in path-ogenesis of nephropathy at its third stage, the stage of incipient nephropathy. Microalbuminuria is followed by overt nephropathy and end- stage renal disease of irreversible renal damage. Early detection of microal-buminuria has a decisive role in the healthy survival of diabetics. Urine albumin excretion rate and albumin creatinine ratio on timed urine samples, early morning samples or spot urine are of beneficial use. Ayurve-da describes diabetes mellitus as Prameha roga in which the ma

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Iquebal, Mir Asif, Pallavi Mishra, Ranjeet Maurya, Sarika Jaiswal, Anil Rai, and Dinesh Kumar. "Centenary of Soil and Air Borne Wheat Karnal Bunt Disease Research: A Review." Biology 10, no. 11 (2021): 1152. http://dx.doi.org/10.3390/biology10111152.

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Karnal bunt (KB) of wheat (Triticum aestivum L.), known as partial bunt has its origin in Karnal, India and is caused by Tilletia indica (Ti). Its incidence had grown drastically since late 1960s from northwestern India to northern India in early 1970s. It is a seed, air and soil borne pathogen mainly affecting common wheat, durum wheat, triticale and other related species. The seeds become inedible, inviable and infertile with the precedence of trimethylamine secreted by teliospores in the infected seeds. Initially the causal pathogen was named Tilletia indica but was later renamed Neovossia

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Amatya, Neha, David Yin-wei Lin, and Amy H. Andreotti. "Dynamic regulatory features of the protein tyrosine kinases." Biochemical Society Transactions 47, no. 4 (2019): 1101–16. http://dx.doi.org/10.1042/bst20180590.

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Abstract The SRC, Abelson murine leukemia viral oncogene homolog 1, TEC and C-terminal SRC Kinase families of non-receptor tyrosine kinases (collectively the Src module kinases) mediate an array of cellular signaling processes and are therapeutic targets in many disease states. Crystal structures of Src modules kinases provide valuable insights into the regulatory mechanisms that control activation and generate a framework from which drug discovery can advance. The conformational ensembles visited by these multidomain kinases in solution are also key features of the regulatory machinery contro

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Peters, Xylia Q., Thembeka H. Malinga, Clement Agoni, Fisayo A. Olotu, and Mahmoud E. S. Soliman. "Zoning in on Tankyrases: A Brief Review on the Past, Present and Prospective Studies." Anti-Cancer Agents in Medicinal Chemistry 19, no. 16 (2020): 1920–34. http://dx.doi.org/10.2174/1871520619666191019114321.

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Background: Tankyrases are known for their multifunctionalities within the poly(ADPribose) polymerases family and playing vital roles in various cellular processes which include the regulation of tumour suppressors. Tankyrases, which exist in two isoforms; Tankyrase 1 and 2, are highly homologous and an integral part of the Wnt β -catenin pathway that becomes overly dysregulated when hijacked by pro-carcinogenic machineries. Methods: In this review, we cover the distinct roles of the Tankyrase isoforms and their involvement in the disease pathogenesis. Also, we provide updates on experimentall

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Crespo-Barrios, Jose. "Vaxtherapy, a Multiphase Therapeutic Protocol Approach for Longvax, the COVID-19 Vaccine-Induced Disease: Spike Persistence as the Core Culprit and Its Downstream Effects." Diseases 13, no. 7 (2025): 204. https://doi.org/10.3390/diseases13070204.

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Background/Objectives: Chronic illness after COVID-19 vaccination (longvax) lacks a therapeutic protocol anchored in pathophysiology. Persistent vaccine derived spike protein appears to trigger microvascular fibrin amyloid microclots, immune dysfunction, pathogen reactivation and multisystem injury. This article proposes an integrative approach, Vaxtherapy, to tackle these mechanisms. Methods: A narrative synthesis of peer reviewed literature from 2021 to 2025 on spike related injury and vaccine adverse events was conducted, supplemented by clinical case series and mechanistic observations fro

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Diamanti, K., and S. M. Nikolaou. "Researching the Social Impact of the COVID-19 Pandemic on Students in Greece." European Journal of Development Studies 1, no. 3 (2021): 26–32. http://dx.doi.org/10.24018/ejdevelop.2021.1.3.35.

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The COVID-19 pandemic has dramatically changed the lives of people around the world, causing constraints, pressures, and deviations from habits as well as necessary survival activities. Its sweeping and leveling character has not left unaffected any part or any structure of our society, above all education. The lockdown and social alienation imposed on people as measures to stop the transmission of the disease has caused social, cognitive, and psychosomatic consequences, especially in the student world. This is not only because the learning process was initially interrupted and then replaced w

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Montess, Michael. "Demedicalizing the Ethics of PrEP as HIV Prevention: The Social Effects on MSM." Public Health Ethics 13, no. 3 (2020): 288–99. http://dx.doi.org/10.1093/phe/phaa016.

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Abstract In order to demedicalize the ethics of pre-exposure prophylaxis (PrEP) as HIV prevention, I consider the social effects on men who have sex with men (MSM). The Centers for Disease Control and Prevention (CDC) considers MSM to be the highest risk group for contracting HIV in the USA. The ethics of using PrEP as HIV prevention among MSM, however, has both a medical dimension and a social dimension. While the medical dimension of the ethics of PrEP includes concerns about side effects, drug resistance and distribution, the social dimension of the ethics of PrEP includes concerns about st

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Akbar, Aqdar A., Noura Al-Sumait, Hanan Al-Yahya, Mohammad Y. Sabti, and Muawia A. Qudeimat. "Knowledge, Attitude, and Barriers to Fluoride Application as a Preventive Measure among Oral Health Care Providers." International Journal of Dentistry 2018 (2018): 1–8. http://dx.doi.org/10.1155/2018/8908924.

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Objective. To investigate the knowledge, attitude, and possible barriers to fluoride application among oral health-care providers in Kuwait.Methods. A validated self-administered questionnaire was distributed to a random sample of 291 dentists. The questionnaire included four categories: dentists’ characteristics, knowledge of and attitude towards fluoride application, factors influencing decision-making on prescription of fluoride, and the clinician’s perception of own knowledge. Means, group differences, and logistic regression were calculated.Results. 262 completed the questionnaire (respon

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Valsa, Gjovalin, and Enkelejda Shkurti. "Universal Epidemiology of Insidious Meningococcal Syndrome." European Journal of Interdisciplinary Studies 1, no. 1 (2015): 25. http://dx.doi.org/10.26417/ejis.v1i1.p25-36.

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Neisseria meningitidis is one of the principal sources of bacterial meningitis worldwide and can as well cause sepsis, pneumonia, and further expressions. In states with elevated widespread rates, the illness load puts a huge tension on the public health structure. The universal epidemiology of persistent meningococcal disease (IMD) diverges distinctly by area and in due course. This appraisal summarizes the burden of IMD in diverse states and recognizes the highest-incidence countries where habitual preventive programs aligned with Neisseria meningitidis would be essentially profitable in off

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Kushner, B. H., N. K. Cheung, M. P. LaQuaglia, et al. "International neuroblastoma staging system stage 1 neuroblastoma: a prospective study and literature review." Journal of Clinical Oncology 14, no. 7 (1996): 2174–80. http://dx.doi.org/10.1200/jco.1996.14.7.2174.

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PURPOSE To gain insight into the management of non-metastatic neuroblastoma by examining clinical and biologic features of International Neuroblastoma Staging System (INSS) stage 1 tumors. METHODS Patients were staged by both the INSS and the Evans staging system and were evaluated for biologic prognostic factors. Patients with INSS stage 1 received no cytotoxic therapy. The literature was reviewed for clinical and biologic data about INSS stage 1. RESULTS We evaluated 10 consecutive patients (median age, 17.5 months) with INSS stage 1; all remain disease-free (median follow-up duration, >

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Hewish, Madeleine, Gordon Stamp, Loretto Puckey, et al. "Impact of mismatch repair (MMR) testing on colorectal cancer (CRC) oncology clinical practice." Journal of Clinical Oncology 30, no. 4_suppl (2012): 603. http://dx.doi.org/10.1200/jco.2012.30.4_suppl.603.

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603 Background: MMR deficiency (dMMR) has been reported in 15% of CRC, but with a lower frequency in advanced disease. Most cases are due to sporadic MLH1 promoter hypermethylation (often with BRAF mutations), with a minority reflecting germline mutations in MLH1, MSH2, PMS2, or MSH6 (Lynch Syndrome [LS]). The Revised Bethesda Guidelines (RBG) are one means of selecting individuals at risk of LS for further assessment, but will miss a proportion of cases. Methods: We screened all consenting patients for eligibility for CRC trials recruiting specific genetic aberrations, which included MMR asse

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Cheema, Muhammad Rafay Shahzad. "Minimally invasive Coronary artery bypass graft: Is this the future of traditional CABG?" Journal of the Pakistan Medical Association 73, no. 6 (2023): 1359–60. http://dx.doi.org/10.47391/jpma.8420.

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Madam, Minimally Invasive Coronary Artery Bypass Graft (MICS CABG) is a newly developed cardiac surgical technique that eschew median sternotomy and its correlated intricacies, while encouraging rehabilitation and conserving the advantages of surgical revascularization. For several decades, guidelines have stated coronary artery bypass grafting (CABG) as the benchmark revascularization procedure for multivessel and left main coronary artery disease (CAD)1. Nevertheless, CABG by sternotomy is an immensely intrusive measure correlated with various post-surgical adverse consequences. Furthermore,

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Rao, Shobha, Pooja Gaigaware, and Amol P. Mankar. "Adverse Anthropometric Profile and Blood Pressure among Young (<40 yrs) Urban Adult Males from Pune, India." Indian Journal of Nutrition and Dietetics 53, no. 2 (2016): 194. http://dx.doi.org/10.21048/ijnd.2016.53.2.4300.

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High prevalence rates of Non Communicable Diseases (NCDs), particularly hypertension and the precedence in its age at onset in developing countries including India, demands identification of risk factors especially among urban young populations. Working young males from Pune, India (n=254) were measured for weight, height, Body Mass Index (BMI), Waist Circumference (WC) Waist Hip Ratio (WHR), Body Fat (BF), Visceral Fat (VF) and blood pressure; 72.5% were overweight, 48.4 % were obese (BMI≥25) while 68.9% were obese using body fat criterion. Central obesity (WC≥90) was 38.2% and was almost hal

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Vidusa, Liga, Oskars Kalejs, Aija Maca-Kaleja, and Ilze Strumfa. "Role of Endomyocardial Biopsy in Diagnostics of Myocarditis." Diagnostics 12, no. 9 (2022): 2104. http://dx.doi.org/10.3390/diagnostics12092104.

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Endomyocardial biopsy as the cornerstone of diagnostics has been re-evaluated throughout the years, leaving unanswered questions on the precedence of it. The reported incidence of myocarditis has increased during the pandemic of coronavirus disease 2019 (COVID-19), reinforcing discussions on appropriate diagnostics of myocarditis. By analysis of evidence-based literature published within the last demi-decade, we aimed to summarize the most recent information in order to evaluate the current role of endomyocardial biopsy in diagnostics and management of myocarditis. For the most part, research

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Alrefaei, Abdulwahed Fahad, Ross Low, Neil Hall, et al. "Multilocus Analysis Resolves the European Finch Epidemic Strain of Trichomonas gallinae and Suggests Introgression from Divergent Trichomonads." Genome Biology and Evolution 11, no. 8 (2019): 2391–402. http://dx.doi.org/10.1093/gbe/evz164.

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Abstract In Europe, Trichomonas gallinae recently emerged as a cause of epidemic disease in songbirds. A clonal strain of the parasite, first found in the United Kingdom, has become the predominant strain there and spread to continental Europe. Discriminating this epidemic strain of T. gallinae from other strains necessitated development of multilocus sequence typing (MLST). Development of the MLST was facilitated by the assembly and annotation of a 54.7 Mb draft genome of a cloned stabilate of the A1 European finch epidemic strain (isolated from Greenfinch, Chloris chloris, XT-1081/07 in 2007

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