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Dissertations / Theses on the topic 'Diseases. Heart'

Author: Grafiati

Published: 4 June 2021

Last updated: 31 July 2024

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1

Savatteri, Giuseppe. "Enviromental factors influencing heart diseases." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2020.

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È importante individuare strategie e meccanismi per sfruttare le opportunità offerte dalla digitalizzazione in ambito sanitario delle attività e dalla gestione dei Big Data per migliorare efficienza, monitoraggio, prevenzione e cura delle patologie. possibilità di applicazione della medicina di precisione, refertazione in anatomia patologica e automazione della raccolta dati. Il lavoro di tesi è incentrato sulle problematiche legate alle malattie cardio-cerebrovascolari e la loro correlazione con il territorio con cui i soggetti interagiscono. È stato realizzato un nuovo sistema di monitor

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2

Swerdan, Stephanie. "Modeling Heart Diseases in Drosophila." Thesis, The University of Arizona, 2012. http://hdl.handle.net/10150/244831.

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Fragile X mental retardation protein (FMRP) plays an important role in heart development and disease. Here we set out to create a Drosophila model of heart disease that will complement the existing mouse model based on Fragile X protein deficiency. Proteins within the Fragile X family are RNA binding proteins that control the translation of specific RNAs. Previous studies have shown that loss of Fragile X mental retardation protein, autosomal homolog 1 (FXR1) leads to heart phenotypes in the mouse. The Drosophila model will allow us to perform rapid genetic rescue experiments to identify speci

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3

Hopmeyer, Joanne. "Effect of physiologic parameters on the quantification of mitral regurgitation using the flow convergence method." Diss., Georgia Institute of Technology, 1996. http://hdl.handle.net/1853/10969.

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4

Phoku, Nkosinathi Terrence. "Cardiovascular risk factors among 15-20 years old rural subjects residing in Dikgale Demographic Surveillance Site (DDSS), Limpopo Province." Thesis, University of Limpopo (Turfloop Campus), 2013. http://hdl.handle.net/10386/1048.

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Thesis (M.Sc. (Chemical Pathology) --University of Limpopo, 2013<br>Cardiovascular diseases (CVDs) are among one of the well documented conditions and pose a significant health burden in the world as they areconsidered to be of adult onset. However, recent studies have shown that in developed countries CVD risk factors are becoming prevalent in young people which isof great concern. Therefore, the aim of this study was to determine if CVD risk factors are present in young subjects aged 15-20 years of age residing in a rural area of a developing country. Methods: Subjects aged between 15-20 ye

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5

Nitoiu, Daniela. "Insights into molecular and functional mechanisms behind inherited heart and skin disorders." Thesis, Queen Mary, University of London, 2015. http://qmro.qmul.ac.uk/xmlui/handle/123456789/8911.

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Desmosomes are macromolecular, dynamic and adaptable complexes that connect intermediate filaments of neighboring cells in a variety of tissues, generating a large mechanically resilient structure. The importance of maintaining desmosome homeostasis for tissue integrity and optimal organ function has been revealed through the identification of desmosome-associated disorders and mechanistic studies into desmosome regulation. This thesis focuses on inherited skin and heart conditions linked to mutations in desmosomal genes or in genes believed to be implicated in desmosome regulation. Part of th

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6

Burleson, Armelle Cagniot. "Analysis of turbulent jets for the determination of heart valve leakage." Diss., Georgia Institute of Technology, 1993. http://hdl.handle.net/1853/11307.

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7

李詠鸞 and Wing-luen Lee. "Multidisciplinary cardiac program for patients with heart failure." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43251328.

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8

Tveresovskiy, A. "Exercise as a prophylaxis of heart diseases." Thesis, Sumy State University, 2014. http://essuir.sumdu.edu.ua/handle/123456789/45417.

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Over the past century we have become increasingly sedentary due to the technical advancements of today's world. Studies have shown that the decline in our physical activity associated with these advancements plays a great role in the decline of our health. Cardiovascular diseases are the main cause of mortality in almost all countries, accounting for 36% of all deaths in 2013. They cover a range of diseases related to the circulatory system, including ischemic heart disease and cerebrovascular disease (or stroke). A sedentary lifestyle is one of the 5 major risk factors (along with high blood

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9

Alsalamah, Mashail. "Heart diseases diagnosis using artificial neural networks." Thesis, Coventry University, 2017. http://curve.coventry.ac.uk/open/items/a9564d2b-df62-4573-8888-cabdbbdcd4e0/1.

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Information technology has virtually altered every aspect of human life in the present era. The application of informatics in the health sector is rapidly gaining prominence and the benefits of this innovative paradigm are being realized across the globe. This evolution produced large number of patients’ data that can be employed by computer technologies and machine learning techniques, and turned into useful information and knowledge. This data can be used to develop expert systems to help in diagnosing some life-threating diseases such as heart diseases, with less cost, processing time and i

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10

Heiser, Claire Anne. "Personality predictors of coronary heart disease." Thesis, Virginia Polytechnic Institute and State University, 1985. http://hdl.handle.net/10919/50027.

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Fifty percent of the diagnosed cases of coronary heart disease in the United States are of unknown etiology. This study proposed that five personality traits— achievement, dominance, aggression, succorance and Critical Parent—differentiate individuals with coronary heart disease manifestations. The ultimate goal of this research was to formulate a predictive profile of at-risk individuals of developing coronary heart disease. Cardiac rehabilitation units' participants from across the United States were recruited as subjects. Randomly selected cardiac rehabilitation units were sent an initial

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11

Lefebvre, Xavier. "Systolic anterior motion of the mitral valve in obstructive hypertrophic cardiomyopathy : an in-vitro study." Diss., Georgia Institute of Technology, 1992. http://hdl.handle.net/1853/11712.

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12

Dal-Santo, Mary Gail. "Evaluation of an early discharge service for cardiac rehabilitation at home." Thesis, University of British Columbia, 1987. http://hdl.handle.net/2429/26198.

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This study evaluates the outcomes of a hospital-based cardiac rehabilitation program designed to deliver the first phase of cardiac rehabilitation services at home. The program was established in a community hospital in 1985, operating under the administration of the hospital's Medical Day Centre. Patients suffering from acute myocardial infarction (MI) are referred to the program by their physician and receive services from a cardiac nurse specialist immediately upon discharge. The services continue for a period of 6 weeks. The outcomes of importance in the study are the effects of the progra

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13

Human, Lucille. "Homocystinuria and hyperhomocysteinaemia in the Western Cape." Thesis, [S.l. : s.n.], 2002. http://dk.cput.ac.za/cgi/viewcontent.cgi?article=1020&context=td_ctech.

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14

Yao, Guiqing. "The economic evaluations of interventions for heart diseases." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/1058/.

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The primary aim of the thesis was to report new cost-effectiveness evidence in the clinical area of heart disease. Following a review of published empirical work, this was achieved by undertaking three new cost-effectiveness studies: one in nurse-led secondary prevention clinics for coronary heart disease in primary care, one on cardiac resynchronisation therapy with or without an implantable cardioverter defibrillator in chronic heart failure, and the final one on a new drug therapy, nebivolol, compared with standard treatment in elderly patients with heart failure. The second aim of the thes

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15

Makubalo, Zola. "Mutation screening of candidate genes and the development of polymorphic markers residing on chromosome 19q13.3, the progressive familial heart block I gene search area." Thesis, Stellenbosch : Stellenbosch University, 2000. http://hdl.handle.net/10019.1/51838.

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Thesis (MSc)--Stellenbosch University, 2000.<br>ENGLISH ABSTRACT: Progressive familial heart block type I (PFHBI) is a cardiac ventricular conduction disorder of unknown cause associated with risk of sudden death, which has been described in several South African families. Clinically, PFHBI is characterised by right bundle branch block on ECG, which may progress to complete heart block, necessitating pacemaker implantation. The disease shows an autosomal dominant pattern of inheritance with evidence of genetic anticipation. Using genetic linkage analysis, the PFHBI-causative gene was map

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16

Boyers, Albert S. "SPECT myocardial perfusion scans : a left ventricular defect size estimation algorithm and a three dimensional computer simulation." Diss., Georgia Institute of Technology, 1991. http://hdl.handle.net/1853/14879.

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17

Kunutsor, Setor Kwadzo. "Markers of liver dysfunction and risk of coronary heart disease." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708216.

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18

Zdravkovic, Slobodan. "Coronary heart disease in Swedish twins : quantitative genetic studies /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-771-5/.

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19

Cho, Jinsoo. "Velocity-based cardiac segmentation and motion-tracking." Diss., Available online, Georgia Institute of Technology, 2004:, 2003. http://etd.gatech.edu/theses/available/etd-04082004-180106/unrestricted/cho%5Fjinsoo%5F200312%5Fphd.pdf.

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20

Retzner, Rebecca J. "Examination of the registered dietitian's role in the implementation of dietary interventions to patients in cardiovascular rehabilitation phase II programs." Virtual Press, 2004. http://liblink.bsu.edu/uhtbin/catkey/1286763.

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The purpose of this research study was to examine the nature and scope of nutrition counseling and/or education available to cardiac patients and the role of the Registered Dietitian (RD) in Cardiac Rehab Phase II Programs. One hundred and fifty programs were surveyed in regards to their program and the programs elements in regards to nutrition topics. To our knowledge, this is the first study to systematically examine the nature and scope of nutrition counseling and/or education and the role of the Registered Dietitian in Cardiac Rehab Phase II Programs.The results indicated that almost 75% o

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21

Bailey, Barry D. "Physiological responses, perceptual responses and target heart rate compliance of coronary heart disease patients during walk-jog exercise." Thesis, Virginia Polytechnic Institute and State University, 1987. http://hdl.handle.net/10919/91082.

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Nine male CHD patients volunteered for testing to determine variations in heart rate response (HR), walk-jog velocity (W) and compliance to the target heart rate zone under three monitoring conditions. Determination of variations in W, peripheral perceived exertion (RPE<sub>L</sub>) chest perceived exertion (RPE<sub>C</sub>) and post-exercise lactate accumulation (La) during exercise which was held constant between 60-80% maximum HR reserve were also made. Procedures consisted of three 20 min walk-jog exercise conditions. First, two baseline condition (BC) trials were performed on separate day

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22

Carlhäll, Carljohan. "Annular dynamics of the human heart : novel echocardiographic approaches to assess ventricular function /." Linköping : Univ, 2004. http://www.bibl.liu.se/liupubl/disp/disp2004/med871s.pdf.

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23

Green, Kerrie L. "A descriptive analysis of cardiac rehabilitation education programs." Virtual Press, 2000. http://liblink.bsu.edu/uhtbin/catkey/1177976.

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The purpose of this research was to obtain information on the content of education within cardiac rehabilitation programs, methods of administering education, what the barriers are to providing education and which professionals administer education.To reach this goal, a questionnaire was modified from a previous study and a pilot study was undertaken to establish reliability of the questionnaire. The questionnaire was then sent to a sample of 100 directors of cardiac rehabilitation programs belonging to The American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR). The quest

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24

Aachi, Venkat Raghav. "Preliminary Characterization of Mitochondrial ATP-sensitive Potassium Channel (MitoKATP) Activity in Mouse Heart Mitochondria." PDXScholar, 2009. https://pdxscholar.library.pdx.edu/open_access_etds/1667.

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Myocardial ischemia, infarction, heart failure and arrhythmias are the manifestations of coronary artery disease. Reduction of ischemic damage is a major concern of cardiovascular biology research. As per recent studies, the mitochondrial ATP-sensitive potassium channel (mitoKATP) opening is believed to play key role in the physiology of cardioprotection, protection against ischemia-reperfusion injury or apoptosis. However, the structural information of mitoKATP is not precisely known. Elucidating the structural integrity and functioning of the mitoKATP is therefore a major goal of cardiovascu

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25

Rhodes, Philip G. "Ability of Lp-PLA₂ to correctly identify women with elevated carotid IMT." Muncie, IN : Ball State University, 2009. http://cardinalscholar.bsu.edu/669.

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26

Luk, Ting-hin, and 陸庭軒. "Effect of cardiac rehabilitation on vascular function in patients withcoronary artery disease." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45153000.

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27

Lai, Tik-man Clare, and 賴迪雯. "Circulating biomarkers and right ventricular function in adolescents and young adults with congenital heart disease." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/197541.

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The population of adolescent and adults with congenital heart disease (CHD) has grown rapidly. Right ventricular (RV) dysfunction remains an important issue of concern in the long-term follow up of these patients. While circulating biomarkers have shown promise in the assessment and monitoring of adult patients with left heart diseases, little is known of the role of biomarkers in reflecting RV performance in CHD patients. Emerging circulating biomarkers that reflect underlying pathophysiologic processes have gained increasing attention. These include inflammatory cytokines namely tumour n

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28

Coe, Ellen Moster. "The correlation between changes in conicity index and changes in other risk factors for coronary heart disease at baseline and after a six- month intervention program." Virtual Press, 1995. http://liblink.bsu.edu/uhtbin/catkey/941352.

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The emphasis of the study was to determine the degree of correlation between the Conicity Index and known risk factors for heart disease. Conicity Index was shown in one study to be a useful screening tool in assessing the relationship between body composition and risk for heart disease. This study was designed to provide nutrition education and teach lifestyle modification to fourteen Veteran's Affairs patients. Change in specific risk factors including Waist-to-Hip Ratio, Body Mass Index, serum lipid levels and dietary intakes were correlated with change in Conicity Index over the six month

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29

Neubeck, Alicia Helen. "Increasing access to secondary prevention of cardiovascular disease." Thesis, The University of Sydney, 2011. https://hdl.handle.net/2123/27329.

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Background: Access to secondary prevention remains disconcertingly low despite proven benefits. The objectives of this thesis were: to evaluate telehealth models of secondary prevention; to determine barriers to participation in secondary prevention; to evaluate the long-term outcomes of a previously proven telehealth model, CHOICE (Choice of Health Options In prevention of Cardiovascular Events); to determine the replicability and generalisability of CHOICE; and to determine future directions for delivery of secondary prevention. Methods: Mixed methods were utilised to achieve the obje

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30

LeRoy, James Allan 1955. "THE INCIDENCE AND PREDICTORS OF POST-SURGICAL CONFUSION IN CARDIAC TRANSPLANT RECIPIENTS (POST-CARDIOTOMY DELERIUM, HEART TRANSPLANTATION, OPEN-HEART SURGERY)." Thesis, The University of Arizona, 1986. http://hdl.handle.net/10150/275554.

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31

Chatzimavroudis, George P. "Quantification of valvular regurgitation with magnetic resonance phase velocity mapping." Diss., Georgia Institute of Technology, 1997. http://hdl.handle.net/1853/11808.

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32

Austin, Jacky. "A comparison of cardiac rehabilitation versus standard care in elderly patients with heart failure." Thesis, University of South Wales, 2003. https://pure.southwales.ac.uk/en/studentthesis/a-comparison-of-cardiac-rehabilitation-versus-standard-care-in-elderly-patients-with-heart-failure(c61f6019-a868-46dc-a828-6fac2ba27b8d).html.

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Heart failure, a condition predominantly affecting the elderly, represents an ever increasing clinical and financial burden for the NHS. Patients with symptomatic heart failure have a poor prognosis and a high degree of morbidity. Current research findings suggest that enhancement of self-care through education, optimisation of pharmacological therapy, exercise training, lifestyle modification and counselling improves patient outcomes and reduces hospitalization. Cardiac rehabilitation, a service that incorporates all the aforementioned components, has yet to be evaluated in heart failure mana

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33

Darwich, Rami. "Functional Analysis of KLF13 in the Heart." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/34317.

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Congenital heart defects (CHD) are the largest class of birth defects in humans and are a major cause of infant mortality and morbidity. Deciphering the molecular and genetic etiologies central for heart development and the pathogenesis of congenital heart diseases (CHD) is a challenging puzzle. We have previously demonstrated that the zinc-finger kruppel-like transcription factor KLF13, expressed predominantly in the atria, binds evolutionarily conserved regulatory elements known as CACC-boxes and transcriptionally activates several cardiac promoters. KLF13 loss of function in Xenopus emb

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34

Cao, Fei. "Chlamydia pneumoniae, toll-like receptors and pathogenesis of atherosclerotic heart disease." View the abstract Download the full-text PDF version (on campus access only), 2007. http://etd.utmem.edu/ABSTRACTS/2007-022-Cao-index.html.

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Thesis (Ph.D. )--University of Tennessee Health Science Center, 2007.<br>Title from title page screen (viewed on May 16, 2008 ). Research advisor: Gerald I. Byrne, Ph.D. Document formatted into pages (xi, 114 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 65-107).

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35

Spinner, Erin M. "Tricuspid valve mechanics: understanding the effect of annular dilatation and papillary muscle displacement." Diss., Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/45754.

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Tricuspid regurgitation (TR), back flow of blood from the right ventricle to the right atrium, has been reported in approximately 85% of the population, with 16% having mild or severe TR. Patients with untreated moderate to severe TR are likely to experience decreased exercise capacity and have increased morbidity and mortality, thus affecting the patient's quality of life. Current methods of repair offer limited rates of success, and many patients require further operations to correct returning levels of TR. Incomplete repair may be due to incomplete understanding of the functional anatomy a

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36

Hadian, Mojtaba. "Study of collagen structure in canine myxomatous mitral valve disease." Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/4383.

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Myxomatous mitral valve disease (MMVD) is the single most common acquired cardiac disease of dogs, and is a disease of significant veterinary importance. It also bears close similarities to mitral valve prolapse in humans and therefore is a disease of emerging comparative interest. Realising the importance of collagen fibres in mitral heart valves and considering the paramount significance of myxomatous mitral valve disease, a better understanding of the pathogenesis of MMVD is essential. Thus, this study was designed to investigate the changes in collagen molecules, including fibril structure

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37

Pangallo, Georgianne. "Effect of a supportive and informational telephone call on threat appraisal in the newly discharged surgical cardiac patient." Virtual Press, 1990. http://liblink.bsu.edu/uhtbin/catkey/722461.

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The purpose of the present study was to test the theoretical relationship of the concepts of informational support and threat appraisal with a sample of surgical cardiac patients twenty-four hours after discharge from the hospital. These discharged patients were adjusting to the transition of hospital to home environment while still recovering from a life threatening illness. They may need varying informational supports to reduce their threat perception of the magnitude of the illness. A convenience sample of thirty-six surgical cardiac patients was assigned to three groups. The groups receive

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38

Lopez-Alvarez, Jordi. "Evaluation of early indicators of disease progression in dogs with degenerative mitral valve disease." Thesis, Royal Veterinary College (University of London), 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.669194.

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39

Warner, Anke Sigrid. "The expression, regulation and effects of inducible nitric oxide synthase in hibernating myocardium." Title page, contents and summary only, 2002. http://web4.library.adelaide.edu.au/theses/09PH/09phw279.pdf.

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Amendments inserted at back. "May 2002" Includes bibliographical references (leaves 237-290) Experiments described in this thesis address the potential role of inducible nitric oxide synthase (iNOS) in hibernating myocardium. Specifically it was sought to establish a cellular model of hibernating myocardium and investigate the expression, regulation and effects of iNOS in this model. Experiments were performed using primary cultures of neonatal rat ventricular myocytes.

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40

Gieseking, Elizabeth Robinson. "Control mechanism for the papillary muscles of the mitral valve : an In Vitro study." Thesis, Georgia Institute of Technology, 1989. http://hdl.handle.net/1853/10912.

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Murchie, Karen J. (Karen Jo) 1973. "Arterial function in hypertension and heart failure." Monash University, Faculty of Medicine, 2000. http://arrow.monash.edu.au/hdl/1959.1/8884.

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42

Royce-Richmond, Judy Elaine. "The effects of knowledge and attitude toward computer assisted instruction on patient education of cardiac risk factors." Virtual Press, 1990. http://liblink.bsu.edu/uhtbin/catkey/722462.

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This study assessed differences in the knowledge of cardiac risk factors and the attitude toward computer assisted instruction (CAI) in cardiac rehabilitation patients instructed by lecture and transparencies or CAI. The quasi-experimental two-group posttest design used a convenience sample of 30 volunteers enrolled in a cardiac rehabilitation program. After randomization, cardiac risk factor instruction was conducted via lecture or the investigator developed CAI. The subjects completed a knowledge instrument which demonstrated content validity and a Kuder-Richardson formula 20 reliability coe

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Valentine, Cassandra E. "The relationship of proxy-efficacy and self-efficacy on the intention to continue cardiac rehabilitation." Virtual Press, 2008. http://liblink.bsu.edu/uhtbin/catkey/1399197.

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Cardiac rehabilitation is profoundly effective at improving physical activity and reducing morbidity and mortality of heart patients. Despite its effectiveness, it is highly underutilized. Research indicates proxy-efficacy and self efficacy positively correlate and predict exercise adherence after Phase II cardiac rehabilitation (Bray & Cowan, 2004; Bray, Brawley, & Millen, 2006). The purpose of the current study aims to investigate the relationship of Phase I patients' proxy-efficacy and self efficacy and their intention to enroll in Phase II cardiac rehabilitation. Thirty participants comple

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Zeng, Ke Han. "Innovative cuboid method to attenuate noises from site-measured heart sound signals." Thesis, University of Macau, 2015. http://umaclib3.umac.mo/record=b3335275.

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Lai, Josanna Yuk-Lin. "Is keeping in or letting out anger good for your heart?" Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/30099.

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Given the presumed importance of cardiovascular reactivity and the role of anger in the development of hypertension and coronary heart disease, this study is the first to jointly examine three related areas (i.e. gender effects, anger direction preference, and opportunity/no opportunity to aggress following an anger Inducing situation). The present study tested the following hypotheses: a) that cardiovascular reactivity would vary as a function of subjects' gender and direction preference; b) that the rate of cardiovascular recovery would vary as a function of anger direction preference and op

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Baril, Jacinthe. "Interaction between circulatory and respiratory exercise adaptation in chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF)." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=97901.

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Chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF) patients show a marked reduction in exercise capacity compared to that of healthy age-matched individuals. While inadequate gas exchange and resulting hypoxemia appears as the primary factor in COPD, an impaired cardiac output is the predominant explanation for the reduced oxygen delivery in CHF. However, the extent of the contributions of other systemic factors remains unclear. In light of the potential interactions between cardiac output (Qc) and pulmonary hyperinflation, there is surprisingly little data thus far o

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47

Simons, Dianne Margaret. "The hydrodynamics of idiopathic hypertrophic subaortic stenosis." Thesis, Georgia Institute of Technology, 1987. http://hdl.handle.net/1853/10257.

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48

Hartnick, Maria Diana. "Echocardiography for early detection of heart disease in high risk diabetic patients." Thesis, Cape Peninsula University of Technology, 2015. http://hdl.handle.net/20.500.11838/1566.

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Masters of Technology: Radiography in the Faculty of Health and Wellness Sciences at the Cape Peninsula University of Technology 2015<br>Introduction: Diabetes mellitus is a chronic disease with a significant impact on personal lifestyle and wellbeing. It is associated with a high prevalence of myocardial disease, the early detection of which is important for prevention of disease progression. Although echocardiography is recognised as a leading cardiovascular imaging modality, there has been limited work on its role in the early detection of diabetes-related myocardial dysfunction. Th

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49

Derry, Christopher William. "The relationship between the hardness of potable water and cardiovascular and ischaemic heart disease mortality in South African urban areas." Master's thesis, University of Cape Town, 1987. http://hdl.handle.net/11427/25808.

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Studies carried out in a number of countries have revealed statistically significant negative correlations between death rates from cardiovascular disease (CVD) or ischaemic heart disease (IHD), and the hardness of local water supplies, a phenomenon which is known as the "water story". These findings have not, however, been universal and it was decided that a study carried out in South Africa with its high CVD and IHD death rates, might yield meaningful results to contradict or support existing findings. In 1983 a pilot study was thus initiated using a spatial model and a more detailed study b

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Ding, Hongliu. "Bone Health and Coronary Heart Disease in Postmenopausal Women with Breast Cancer Treated with Tamoxifen: A Dissertation." eScholarship@UMMS, 2008. https://escholarship.umassmed.edu/gsbs_diss/404.

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Breast cancer, osteoporosis, and coronary heart disease (CHD) are three major threats to women’s health. Postmenopausal women with breast cancer are also at high risk for osteoporosis and CHD. Adjuvant tamoxifen therapy is not only an effective treatment for breast cancer, but has been shown to have a beneficial effect on bone and the cardiovascular system. Although tamoxifen has been convincingly demonstrated to be able to preserve bone mineral density (BMD), an unexpected increase of risk of fractures in patients treated with tamoxifen has been reported. The findings of the association of ta

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