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Dissertations / Theses on the topic 'Diseases of the spine'

Author: Grafiati

Published: 28 May 2022

Last updated: 31 July 2025

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1

Кирічок, О. О. "Засоби та методи фізичної терапії при остеохондрозі попереково-крижового відділу хребта I-II ступеня". Thesis, Сумський державний університет, 2017. http://essuir.sumdu.edu.ua/handle/123456789/61285.

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Аналіз наукової та науково-методичної літератури дозволяє констатувати, що хвороби хребта посідають перше місце за поширеністю серед населення земної кулі. Серед них однією з найбільш поширених патологій є остеохондроз хребта (ОХ). Питома вага його виявів серед усіх захворювань периферійної нервової системи складає від 67% до 95%.

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2

Louw, Adriaan. "Preoperative education for patients undergoing lumbar spine surgery for radiculopathy." Thesis, Stellenbosch : University of Stellenbosch, 2006. http://hdl.handle.net/10019.1/1681.

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Thesis (MScPhysio (Physiotherapy))--University of Stellenbosch, 2006.<br>Postoperative rehabilitation programs have shown little efficacy in decreasing pain and disability in short and long term outcomes for lumbar discectomy. Preoperative education in other disciplines of medicine and physiotherapy has shown to decrease pain and disability postoperatively. No studies to date have been published on preoperative education for spinal lumbar surgery patients with radiculopathy. Objective: The objective of this study was to contribute towards further understanding of the preoperative educational

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3

Cornwall, Jonathan Edgar, and n/a. "The functional morphology of the human thoracolumbar transversospinal muscles." University of Otago. Department of Anatomy & Structural Biology, 2009. http://adt.otago.ac.nz./public/adt-NZDU20090615.144650.

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The thoracolumbar transversospinal muscles are vital in normal function and are implicated in the pathogenesis of different forms of spinal pathology and pain. They are the target for specific forms of clinical intervention such as exercise regimens and the release of �trigger points�, and are often analysed through imaging studies and electromyographic recordings. Despite the importance of these muscles, there is a paucity of knowledge in regard to aspects of their functional morphology. The aim of this thesis was to examine the thoracolumbar transversospinal muscles between the mid-thoraci

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4

Cerroni, Antonietta Maria. "The pathology and epidemiology of spontaneous diseases and disorders of the spine in the rhesus macaques of Cayo Santiago." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0023/NQ49818.pdf.

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5

O'Malley, Jennifer A. "Improving therapeutics for Parkinson's disease." Cincinnati, Ohio : University of Cincinnati, 2009. http://rave.ohiolink.edu/etdc/view.cgi?acc_num=ucin1259079683.

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Thesis (Ph.D.)--University of Cincinnati, 2009.<br>Advisor: Kathy Steece-Collier. Title from electronic thesis title page (viewed Apr. 26, 2010). Keywords: Parkinson; dopamine; dyskinesia; levodopa; dendritic spine; medium spiny neuron. Includes abstract. Includes bibliographical references.

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6

Johnson, Jacqueline Anne. "The Canine Cervical Spine - Kinematics and Micromorphometry." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1274465058.

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7

DA, ROCHA RIBEIRO ANA CLAUDIA. "A SPINE TO NUCLEUS SIGNALING PATHWAY IN ALZHEIMER¿S DISEASE." Doctoral thesis, Università degli Studi di Milano, 2019. http://hdl.handle.net/2434/646847.

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Ring Finger Protein 10 (RNF10) è una proteina messaggero sinaptonucleare localizzata a livello delle sinapsi eccitatorie e associata con la subunità GluN2A del recettore NMDA. Stimolazione dei recettori NMDA contenenti la subunità GluN2A induce il trasporto di RNF10 dalla sinapsi al nucleo e la conseguente espressione di specifici geni bersaglio, alcuni dei quali svolgono un ruolo nella patogenesi della malattia di Alzheimer o nella modulazione della morfologia delle spine dendritiche. E’ inoltre importante osservare come l’espressione di RNF10 sia ridotta negli ippocampi di pazienti con malat

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8

Musardo, S. "MOLECULAR ASPECTS OF ALZHEIMER'S DISEASE PATHOGENESIS: FROM LOCAL SPINE TRAFFICKING TO LONG DISTANCE SPINE TO NUCLEUS SIGNALLING.'TOWARDS NEW THERAPEUTICS INTERVENTION'." Doctoral thesis, Università degli Studi di Milano, 2016. http://hdl.handle.net/2434/352321.

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The molecular pathogenesis of Alzheimer’s disease (AD) is still controversial, although genetic and cell biology findings indicate accumulation of Aβ, especially in soluble oligomeric conformation, as the driving force of synaptic dysfunction with concomitant activation of complex cascade of molecular events leading to dementia. In the last few years, several studies aimed at understanding how Aβ accumulation and assembly compromise synaptic structure and function of excitatory synapses. In this study, we evaluated how Aβ can affect the local and the long-distance trafficking, since the altera

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9

Jee, Larry Donald. "The urological management of children with spinal dysraphism." Master's thesis, University of Cape Town, 1990. http://hdl.handle.net/11427/25677.

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This project was undertaken with the following aims: 1) To generate a data base concerning the management of children with congenital spinal anomalies, who are known to form a significant proportion of the patients being treated in the Department of Paediatric Urology at Red Cross Hospital. 2) To assess the results of the management of these children, with special attention to the goals of therapy, namely preservation of renal function, establishment of urinary continence and protection from urinary tract infection. 3) To compare the treatment methods and results obtained to those repo

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10

Simpson, Andrew Kyle. "The utility of plain radiography in the evaluation of degenerative spine disease." [New Haven, Conn. : s.n.], 2008. http://ymtdl.med.yale.edu/theses/available/etd-12092008-162439/.

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11

梁漢邦 and Hon-bong Leung. "Consequence of paraspinal muscle after posterior lumbar spinal fusion: the histology and electromyography findingsin a rabbit model." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31971179.

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12

Андріянова, Т. В., Володимир Вікторович Андрющенко, Владимир Викторович Андрющенко та Volodymyr Viktorovych Andriushchenko. "Фізична реабілітація при дефектах постави". Thesis, Видавництво СумДУ, 2009. http://essuir.sumdu.edu.ua/handle/123456789/11315.

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У роботі розглядаються проблеми фізичної реабілітації при дефектах постави. Проведені дослідження доводять те, що вчасно призначені, проведені в повному обсязі та регулярно реабілітаційні заходи при порушеннях постави є досить ефективними для профілактики розвитку захворювань хребта і функціонування внутрішніх органів. При цитуванні документа, використовуйте посилання http://essuir.sumdu.edu.ua/handle/123456789/11315

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13

Torén, Anna. "Twisted trunk postures during tractor driving : with special reference to low-back load and exposure /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 1999. http://epsilon.slu.se/avh/1999/91-576-5498-0.pdf.

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14

Peolsson, Annelie. "Functional analysis of the cervical spine : reliability, reference data and outcome after anterior cervical decompression and fusion /." Linköping, 2002. http://www.bibl.liu.se/liupubl/disp/disp2002/med738s.pdf.

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15

Mariúba, Eduardo Sávio de Oliveira. "Avaliação de características clínicas e de exames de imagem que identificam pacientes com síndrome facetária." Botucatu, 2019. http://hdl.handle.net/11449/180756.

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Orientador: Rui Seabra Ferreira Junior<br>Resumo: Introdução: A dor lombar crônica representa uma doença que gera grandes custos sociais e financeiros. A síndrome facetária é uma possível etiologia para a dor lombar, porém de difícil diagnóstico e tratamento. Objetivo: Avaliar se determinados critérios clínicos e de exames de imagem foram capazes de identificar pacientes com a síndrome facetária e confirmar o diagnóstico por meio da infiltração realizada sob escopia em centro cirúrgico. Pacientes e métodos: 38 pacientes de ambos os sexos atendidos no Ambulatório de Cirurgia da Coluna – Ortoped

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16

Ballard, Timothy D. "Cervical Spine Disease and Surgical Intervention in the US Air Force Fighter Aviator Population 2001-2006: An Assessment of Relative Risk." University of Cincinnati / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1214507780.

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17

Espahbodi, Shima. "Investigation of lumbar artery haemodynamics in patients with low back pain and degenerative disc disease of the lumbar spine." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.416129.

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18

Рогоза, І. К. "Ефективне використання засобів пілатесу для корегування структурно-функціональних порушень хребта". Thesis, Сумський державний університет, 2013. http://essuir.sumdu.edu.ua/handle/123456789/33069.

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Наразі проблема формування поведінки, що сприяє збереженню здоров’я, серед студентів отримала новий розвиток. Це викликано тими негативними змінами в фізичному стані студентської молоді, які відбуваються в Україні в останні роки. Особливо часто захворювання й різноманітні структурно-функціональні порушення хребта зустрічаються в студенток вузів. Це викликано, передусім, недостатньою руховою активністю студенток і відсутністю програм для різних рівнів фізичної підготовленості. Як показують дослідження, проведені за останні роки, більше значення для профілактики хребта мають вправи, взяті

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19

VANDERMEULEN, LINA LORNA. "UNDERSTANDING THE EARLY STAGES OF ALZHEIMER¿S DISEASE PATHOGENESIS: CAP2 AS A LINK BETWEEN SPINE DYSMORPHOGENESIS AND THE AMYLOID CASCADE." Doctoral thesis, Università degli Studi di Milano, 2019. http://hdl.handle.net/2434/646592.

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La malattia di Alzheimer (AD) è caratterizzata da depositi di beta-Amiloide (Aβ) e di proteina tau iperfosforilata. L’enzima ADAM10 taglia la Proteina Precursore dell’Amiloide (APP) impedendo la formazione di Aβ. L’attività e la localizzazione sinaptica di ADAM10 sono modulate da proteine che interagiscono con la coda citoplasmatica di ADAM10. Ciò considerato, abbiamo condotto un “two-hybrid screening” che ha permesso l’identificazione di cyclase-associated protein 2 (CAP2) come nuovo partner di ADAM10. Le CAPs sono proteine che legano l’actina e sono coinvolte in rimodellamento del citoschele

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20

Filipe, Fernando Manuel Rana. "Doença do nível adjacente após artrodese da coluna lombar." Faculdade de Medicina de São José do Rio Preto, 2006. http://bdtd.famerp.br/handle/tede/197.

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Made available in DSpace on 2016-01-26T12:51:47Z (GMT). No. of bitstreams: 1 fernandofilipe_dissert.pdf: 443784 bytes, checksum: bb6328cd8296f1c4b222d0c43cdafda1 (MD5) Previous issue date: 2006-02-13<br>Adjacent segment disease is defined as an abnormal process developing in the adjacent level above and/or bellow the arthrodesis of the segment. It is considered a late complication of lumbar spine arthrodesis. It has been very important due to the procedures in the last years. Objective: To evaluate the risk factors associated with the disease at adjacent level as well as its relationship wit

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21

McMahon, Catherine. "The mechanisms underlying normal spike activity of the primary afferent synapse in the cochlea and its dysfunction : an investigation of the possible mechanisms of peripheral tinnitus and auditory neuropathy." University of Western Australia. School of Biomedical and Chemical Sciences, 2004. http://theses.library.uwa.edu.au/adt-WU2003.0034.

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[Truncated abstract] One of the problems in researching tinnitus is that it has often been assumed that the physiological mechanisms underlying the tinnitus percept cannot be objectively measured. Nonetheless, it is generally accepted that the percept results from altered spontaneous neural activity at some site along the auditory pathway, although it is still debated whether it is produced by: synchronisation of activity of adjacent neurones; a change in the temporal pattern of activity of individual neurones; or an increase in the spontaneous firing rate per se. Similarly, it is possible tha

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22

Phinney, Brett Stanley. "The surface conformation of the Sindbis virus spike complex as determined by mass spectrometry based mapping /." Digital version accessible at:, 2000. http://wwwlib.umi.com/cr/utexas/main.

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23

Amini, Mandana. "Analysis of Conditional Knock-out of Calpain Small Subunit, capns1, in Central Nervous System Development and Function." Thesis, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/31360.

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Calpains, a highly conserved family of calcium-dependent cysteine proteases, are divided in two groups; classical and non-conventional calpains. Calpain-1 and calpain-2, the classical ones, are ubiquitously expressed and abundant in the CNS. Findings through different experimental approaches, predominantly pharmacological calpain inhibitors, proposed the necessity of the proteases for the modulation of various biological events particularly in the CNS, or a functional link between calpain and neurodegeneration. Significant functions associated with calpain activity are neuronal proliferation/

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24

Lorenzin, Mariagrazia. "Spine and sacroiliac joints on nuclear magnetic resonance imaging and research of serological biomarkers predictive of severity and disease activity in early axial spondyloarthritis." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3424857.

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Recently several studies have focused on the use of magnetic resonance imaging (MRI) and new biomarkers that might facilitate early diagnosis of axial spondyloarthritis (axSpA) and identify individuals at higher risk of developing the disease. Objectives:The study aimed to identify:1)potentially useful biomarkers for early diagnosis of axSpA and their correlations with disease activity and imaging indices;2)the prevalence of spine and pelvis MRI lesions in patients (pts) with low back pain (LBP);3)the correlation between the site of axial pain and of MRI-lesions.Material and Methods:Seventy-tw

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25

Burgese, Luciana Fortunato. "Radiologia convencional e tomografia computadorizada na avaliação de cães portadores de discopatia cervical: estudo comparativo." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/10/10137/tde-23042007-115839/.

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Foram avaliados 25 cães portadores de discopatia cervical aos exames radiográficos simples, mielografia e tomografia computadorizada. A dor foi o principal sinal clínico em 64% dos casos. Os animais com raça definida foram os mais acometidos (85%), tendo maior incidência da raça Teckel. A faixa etária mais acometida foi entre 7-9 anos (72%). O exame radiográfico simples indicou aspectos compatíveis com extrusão em 14 observações. A mielografia diagnosticou 15 extrusões, 18 protrusões e 4 hérnias de disco e forneceu informações quanto ao grau de compressão medular e extensão das lesões. A tomog

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26

Law, Tsz-kwun, and 羅子冠. "Ultrashort time-to-echo MRI of the cartilaginous endplate and relationship to disc degeneration and Schmorl's nodes, andretrospective study of paediatric spines and the neurocentralsynchondrosis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B47869987.

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Background: An association between cartilaginous endplate (CEP) defects and intervertebral disc (IVD) degeneration has been previously suggested in animal and cadaveric studies. CEP defects may also be involved in Schmorl’s nodes (SN). There have been no previous reports in the literature that describe the use of ultrashort time-to-echo (UTE) MRI to assess the CEP in humans in vivo. In chapter 5 of this thesis, a retrospective study of paediatric spines and the neurocentral synchondrosis (NCS) was singled out to report the incidence of NCS and to raise the hypothesis of NCS as a precur

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Pirolla, Eduardo Henrique. "\"Incidência de pancreatite aguda em pacientes com traumatismo raquimedular agudo\"." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/5/5140/tde-14092006-133959/.

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A pancreatite é o resultado da atividade corrosiva das enzimas digestivas pancreáticas e, independente dos vários agentes etiológicos e dos mecanismos etiopatogênicos, tem como resultado a ativação enzimática intra-parenquimatosa, a destruição tecidual e a necrose isquêmica. Trata-se de uma afecção, grave, com incidência aumentada em vítimas de traumatismo raquimedular. Nesses doentes, a suspeita clínica de pancreatite pode ser difícil, pois os sinais e sintomas podem estar diminuídos ou ausentes em decorrência do déficit sensorial esplâncnico. Avaliaram-se, prospectivamente, 78 doentes com tr

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28

Favre, Jean-François. "Participation de l'activité tonique posturale à la genèse de certaines attitudes scoliotiques : application à la compréhension de certaines contre-performances gestuelles du sportif et à leur éventuelle correction." Paris 10, 1988. http://www.theses.fr/1988PA100061.

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Cette thèse utilise comme support physiologique l’activité tonique posturale orthostatique. Comment des troubles primitifs du système nerveux central peuvent-ils modifier les rapports existants entre les syncinésies musculaires toniques involontaires automatiques ? Le premier chapitre présente la posture de l’homme debout sous l’angle d’un concept de physique ; la place et le maintien du centre de gravité dans le polygone de sustentation. Dans le premier paragraphe sont analysés les aspects histologiques et anatomo-physiologiques : 1) du squelette sous l’aspect fonctionnel postural. 2) du syst

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29

Siddall, Daniel Jonathan. "Patient specific spine models : the development of a laboratory validation spine." Thesis, University of Hull, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.396751.

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30

Freppel, Sébastien. "Interactions visuo-proprioceptives dans les pathologies dégénératives du rachis cervical relevant d'un traitement chirurgical." Thesis, Université de Lorraine, 2013. http://www.theses.fr/2013LORR0284/document.

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La proprioception cervicale joue un rôle important dans le contrôle postural, mais la nature exacte de sa contribution est controversée. Dans certains cas de « coup du lapin », une atteinte posturale a été démontrée, sans que l'atteinte du rachis cervical puisse être tenue pour seule responsable. Malgré la forte prévalence des pathologies cervicales dégénératives, leurs conséquences posturales ont été peu étudiées dans la littérature scientifique. Il n'existe aucune publication centrée sur les deux types de pathologie responsables de névralgies cervicobrachiales : les hernies discales cervical

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31

Liu, Jianzhi. "A two-dimensional human spine simulation and three-dimensional spine model construction." [Gainesville, Fla.] : University of Florida, 2001. http://purl.fcla.edu/fcla/etd/UFE0000329.

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Thesis (M.S.)--University of Florida, 2001.<br>Title from title page of source document. Document formatted into pages; contains xi, 114 p.; also contains graphics. Includes vita. Includes bibliographical references.

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Landstad, Bodil J. "At work in spite of pain : prevention and rehabilitation in two predominantly female workplaces, their effects and further development of analysis methods /." Stockholm : Karolinska Univ. Press, 2001. http://diss.kib.ki.se/2001/91-89428-13-7/.

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Benner, Nicole. "Explorations of the Spine." Thesis, Southern Illinois University at Edwardsville, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10130722.

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Axelsson, Paul. "On lumbar spine stabilization." Lund : Dept. of Orthopedics, Lund University Hospital, 1996. http://catalog.hathitrust.org/api/volumes/oclc/38045390.html.

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Ceran, Murat. "Parametric human spine modelling." Thesis, Loughborough University, 2006. https://dspace.lboro.ac.uk/2134/7958.

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3-D computational modelling of the human spine provides a sophisticated and cost-effective medium for bioengineers, researchers, and ergonomics designers in order to study the biomechanical behaviour of the human spine under different loading conditions. Developing a generic parametric computational human spine model to be employed in biomechanical modelling introduces a considerable potential to reduce the complexity of implementing and amending the intricate spinal geometry. The main objective of this research is to develop a 3-D parametric human spine model generation framework based on a c

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Mihcin, Senay. "Spine modelling for lifting." Thesis, Loughborough University, 2007. https://dspace.lboro.ac.uk/2134/8065.

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Mathematical modelling is widely used in the field of biomechanics. The traditional approach to investigate spine related injuries is to check the strength of the components of the spine. Spinal stability approach focuses on the force polygons formed by the body weight, muscle forces, ligament forces and external load. This force polygon is expected to stay within the boundaries of the spine to ensure stability. Proving the possibility of one force polygon within the spine boundaries proves the stability of the spine. This study focuses on the full curvature of the spine for spinal stability i

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Fathallah, Fadi A. "Coupled spine motions, spine loading and risk of occupationally- related low back disorders /." The Ohio State University, 1995. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487867541730726.

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Hodges, Paul William. "Neuromechanical control of the spine /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-552-2/.

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Przybyla, Andrzej Stefan. "Biomechanics of the cervical spine." Thesis, University of Bristol, 2005. http://hdl.handle.net/1983/845f95ee-39dd-4418-b6ed-200d749f87ae.

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Malinverno, M. "MOLECULAR MECHANISMS REGULATING SPINE REMODELLING." Doctoral thesis, Università degli Studi di Milano, 2010. http://hdl.handle.net/2434/150194.

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N-Cadherin plays an important role during dendrite arborisation, axon guidance and synaptogenesys. In particular, at synaptic sites, it is required for activity-dependent synaptic plasticity and dendritic spine remodeling. Recent studies have shown that N-Cadherin can be cleaved by the metalloproteinase ADAM10. Here we demonstrate that modulating ADAM10 localization and activity at synaptic sites regulates its processing of N-Cadherin. This indices modification of dendritic spines morphology and of composition and function of AMPA receptors. In particular, inhibition of ADAM10 synaptic locali

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Yu, Yuk-ling. "The use of computerised tomography in cervical spondylotic myelopathy and radiculopathy." [Hong Kong : University of Hong Kong], 1985. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12315904.

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42

Mameren, Hendrik van Lieshout F. van. "Motion patterns in the cervical spine." Maastricht : Maastricht : Rijksuniversiteit Limburg ; University Library, Maastricht University [Host], 1988. http://arno.unimaas.nl/show.cgi?fid=5445.

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Zhou, Lei. "Molecular mechanisms regulating dendritic spine morphology." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=106328.

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In the central nervous system, chemical synapses are highly specialized junctions that are known to be critical for communication between neurons. The ability of synapses to change their physiological and structural properties, known as synaptic plasticity, is important for storing information in neural connections. Dendritic spines are small protrusions on dendrites where the majority of glutamatergic synapses form in the brain. In general, a dendritic spine has an enlarged head region that is connected to the dendritic shaft by a narrow neck. This geometry allows spines to function as indivi

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Norris, Christopher Michael. "Functional rehabilitation of the lumbar spine." Thesis, Staffordshire University, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493646.

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Côrte, Ana Filipa Terleira Camacho da. "Cervical spine instability in rheumatoid arthritis." Master's thesis, Faculdade de Medicina da Universidade do Porto, 2010. http://hdl.handle.net/10216/61051.

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Rose, Joseph D. "Carrying and Loading of the Spine." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1356475691.

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Hueston, Susan. "Anthropometric Analysis of the Cervical Spine." Wright State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=wright1315947078.

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Makola, Mbulelo T. "Cervical Spine Biomechanical Behavior and Injury." Wright State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=wright1316534684.

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Bobyn, Justin Daniel. "Improving Outcomes in NF1 Spine Fusion." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/19629.

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NF1 (neurofibromatosis type 1) is a relatively common genetic disease which may be characterized by the presence of scoliosis and altered bone metabolism, amongst its many orthopaedic manifestations. Traditionally, spine fusion procedures have been used to correct and limit the progression of this deformity. NF1 bone healing at the tibia and spine feature impaired bone anabolism, excessive catabolism, and fibrosis. Fibrotic tissue in the tibia and between the vertebrae can lead to pseudarthrosis, which can require substantive clinical intervention. In particular, complications associated with

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Tuttle, Neil. "Posteroanterior Movements of the Cervical Spine." Thesis, Griffith University, 2008. http://hdl.handle.net/10072/366296.

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Abstract :Posteroanterior (PA) movements are commonly used to assess and treat musculoskeletal neck pain but little is known about their relationship to symptoms or treatment effectiveness. The general purpose of this research program was to determine relationships between the manual therapy techniques known as PA movements of the cervical spine and symptoms in patients with neck pain. The specific aims of the studies were to: • Establish a reliable immediate indicator of symptoms in patients with non-acute neck pain that is a good predictor of longer-term change in symptoms. • Develop and es

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