Relevant bibliographies by topics / Disintegration time of tablets

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Academic literature on the topic 'Disintegration time of tablets'

Author: Grafiati
Published: 4 June 2021
Last updated: 6 February 2022

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Journal articles on the topic "Disintegration time of tablets"

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Binti Sarun, Nur Hanisah, Archadian Nuryanti, and Ika Dewi Ana. "The Effect of Chitosan Concentration on Disintegration Time of Amoxicillin Tablet." Key Engineering Materials 884 (May 2021): 298–303. http://dx.doi.org/10.4028/www.scientific.net/kem.884.298.

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The most often prescribed antibiotics by dentists to patients is Amoxicillin. It is usually in the form of capsules and tablets which are hard to swallow, especially for geriatric and pediatric patients. Orally disintegrating tablet (ODT) with the capability to disintegrate inside oral cavity without the need of water required disintegrant agent in its formulation. In this study, chitosan as the product of deacetylation of chitin which originated from exoskeleton of crustacean shells was considered as suitable disintegrant because its swelling characteristic. The aim of this research was to study the effect of chitosan concentration on disintegration time of Amoxicillin tablet. Seventy tablets were made with direct compression method. Five formulas of 250 mg Amoxicillin with chitosan concentration of 2%, 5%, 8%, 11%, and 14% were prepared, with two control groups, i.e. the group of sodium starch glycolate as disintegrant at concentration of 5% as positive control and the group without adding disintegrant into the formula for negative control. Each tablet was tested for their disintegration time using disintegration tester (Erweka). The data of disintegration time of each tablets were recorded and analyzed using non-parametric hypotheses test of Kruskal Wallis. The result of Kruskal Wallis’s test showed significant difference of chitosan concentrations on disintegration time of Amoxicillin tablet (p<0.05). The shortest disintegration time was found at 11% concentration of chitosan. Higher concentration of chitosan (14%) increased the disintegration time of Amoxicillin tablet due to gel-like formation that prolonged tablet disintegration. It was concluded that different concentration of chitosan can affect the disintegration time of Amoxicillin tablet. Further studies were recommended to provide best candidate of ODT for Amoxicillin.
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Sa'adah, Hayatus. "OPTIMASI FORMULA EKSTRAK JAHE MERAH (Zingiber officinale) DENGAN METODE KEMPA LANGSUNG MENGGUNAKAN ANALISIS SIMPLEX LATTICE DESIGN." Jurnal Ilmiah Manuntung 1, no. 1 (January 26, 2017): 47. http://dx.doi.org/10.51352/jim.v1i1.11.

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Processing of medicinal plants into the appropriate dosage form can ensure security during use. It is a motivation in making acceptable dosage form which is easy and convenient to use, especially the manufacture of ethanol extract red ginger tablets using a combination of starch 1500 and amprotab.The study begins with the manufacture of dry extract of red ginger. Optimization of making tablets using a combination of starch 1500 and disintegrator with simplex lattice design using three formulas is done by direct compaction method. Further testing on the tablet hardness, friability and disintegration time.The results showed starch 1500 has a greater influence increase hardness and disintegration time of tablets, as well as lowering the fragility of the tablet. While the interaction of starch 1500 and disintegrator has no effect on the physical tablet. The optimum proportion of the combination of starch 1500 and disintegrator meet the physical requirements of tablets with a ratio of 4: 6 with 7.99 kg hardness, the friability of 0.32% and disintegration time of 2.42 minutes
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Patomchaiviwat, Vipaluk, Suchada Piriyaprasarth, Bunyarit Chaisomboonphan, Chitatharinth Limpoemwuttiporn, and Pornsuda Nuamnoi. "Modification of Starch Extracted from Black Glutinous Rice (Oryza sativa L, Variety Leum Pua) as Tablet Filler." Advanced Materials Research 1060 (December 2014): 58–61. http://dx.doi.org/10.4028/www.scientific.net/amr.1060.58.

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The aim of this study was to investigate the modification of black glutinous rice starch (BGRS) as tablet filler. The black glutinous rice was treated with NaCl and NaOH to obtain BGRS. The native BGRS was modified by pregelatinizaion and prepared as co-composite and used as filler in tablet formulation compared with Starch 1500®. Propranolol was used as a model drug. The properties of tablets including disintegration time were evaluated. Interestingly, the disintegration times of the native BGRS was less than 90s which was faster than Starch 1500®. The results suggest that the native BGRS would be used in fast disintegrating tablets. While the disintegration times of pregelatinized BGRS was more than 30 min. Thus, the pregelatinized BGRS might be used for sustained release tablet. For the co-composite method, PVP K90 in the concentration of 1, 3, 5, 7 and 9 % w/w was incorporated with BGRS. The tablets of the co-composite producing by direct compression method were compared with tablets producing by wet granulation method using PVP K90 as binder. In concentration of 3% w/w PVP K90, the co-composite was comparable to wet granulation method in term of hardness and disintegration time. Thus, it could be used as direct compression filler in pharmaceutical field.
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Patomchaiviwat, Vipaluk, Piriyaprasarth Suchada, Koorattanasiri Popporn, Kanoknirumdom Supaporn, and Rattanasiha Achara. "Evaluation of Native and Pregelatinized Arrowroot (Maranta Arundinacea) Starches as Disintegrant in Tablet Formulation." Advanced Materials Research 197-198 (February 2011): 127–30. http://dx.doi.org/10.4028/www.scientific.net/amr.197-198.127.

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The purpose of this study was to investigate the disintegrating properties of native arrowroot starch and pregelatinized arrowroot starch in comparison with corn starch and sodium starch glycolate (Explotab®). Tablets were prepared by direct compression. The tablet formulations contained dibasic calcium phosphate as filler and magnesium stearate as lubricant. Each starch at various concentrations between 2-10 % w/w was used in formulation as disintegrant. The swelling volume and weight of starches and disintegration time of tablets were evaluated. At 2% w/w concentration of starch, the pregelatinizaed starch provided disintegration time faster than the native starch (2.5 times). The disintegration time of 2% w/w pregelatinized arrowroot starch was comparable to Explotab and faster than that of native starch. The disintegration time of native starch at the concentration of 4, 6 and 10 %w/w was comparable to that of corn starch and Explotab®. Native arrowroot starch and pregelatinized arrowroot starch could be used as effective disintegrants in tablet formulation.
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Nestorovska-Gjosevska, Biljana Nestorovska-Gjosevska, Marija Glavas-Dodov, and Katerina Goracinova. "Orally disintegrating tablet: formulation design and optimisation using Response Surface Methodology." Macedonian Pharmaceutical Bulletin 51 (2005): 15–22. http://dx.doi.org/10.33320/maced.pharm.bull.2005.51.003.

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The objective of this study was to develop diazepam orally disintegrating tablets and to optimize tablets characteristics using response surface methodology (RSM). Tablets were prepared by direct compression of mixture containing mannitol, copovidone, crosspovidone flavor and lubricant. A full factorial design for 2 factors at 3 levels each was applied to investigate the influence of 2 formulation variables on the mechanical strength/hardness, the percent of friability, disintegration time and dissolution of the poorly soluble active ingredient. The amounts of copovidone and crosspovidone were taken as independent variables. All data were analyzed by using statistical program. The results of multiple linear regression analysis revealed that for obtaining a rapidly disintegrating dosage form, tablets should be prepared using an optimum concentration of crospovidone and copovidone. A contour plot is also presented to graphically represent the effect of the independent variables on the tablet hardness, disintegration time, percentage friability and dissolution. A checkpoint batch was also prepared to prove the validity of the evolved mathematical model. 3 level factorial design allowed us to obtain ODT with rapid disintegration and dissolution of the active ingredient with desirable properties of low tablet friability and appropriate mechanical strength (hardness) of the tablet.
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Chue, Pierre, Barry Jones, Cindy C. Taylor, and Ruth Dickson. "Dissolution Profile, Tolerability, and Acceptability of the Orally Disintegrating Olanzapine Tablet in Patients with Schizophrenia." Canadian Journal of Psychiatry 47, no. 8 (October 2002): 771–74. http://dx.doi.org/10.1177/070674370204700809.

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Objectives: This pilot study investigates the dissolution profile, tolerability, and acceptability of an orally disintegrating olanzapine tablet in patients with schizophrenia. Method: Eleven patients with schizophrenia stabilized on oral olanzapine (mean dosage 12.7 mg daily [SD5.2]) were given an orally disintegrating olanzapine tablet, rather than their usual tablet, daily for 7 days. At each visit, visual assessments were made for elapsed time to initial disintegration (every 15 seconds) and complete disintegration (every 1 minute). At the end of the study, patients completed a drug-acceptance questionnaire. Results: The mean time to initial disintegration was 15.78 seconds, and mean time to complete disintegration was 0.97 minutes. All patients found the orally disintegrating tablet acceptable and expressed positive comments. Nonserious clinically significant adverse events, asthenia, purpuric rash, headache, depression, and insomnia (preexisting, except for asthenia and insomnia) were reported in 3 patients. Conclusion: The orally disintegrating olanzapine tablet disintegrates rapidly and is a well-tolerated and acceptable alternative to standard olanzapine tablets in patients with schizophrenia.
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Kundawala, Aliasgar, Pratik Patel, Khushbu Chauhan, Anjali Desai, and Dhwani Kapadia. "Formulation and Optimization of Orodispersible Tablet of Loratadine Using Box Behnken Design." Journal of Drug Delivery and Therapeutics 9, no. 4-A (August 30, 2019): 86–94. http://dx.doi.org/10.22270/jddt.v9i4-a.3402.

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In present study Orodispersible tablets (ORDT) of Loratadine were prepared and optimized. Solid dispersion of Loratadine- β cyclodextrin complex were prepared and used in preparation of Orodispersible tablets. Various super-disintegrating agent like Cross carmellose sodium, Cross povidone and Kyron T-314 were employed for faster disintegrating effect. The 24 factorial and Box-Behnken design were utilized to optimize the tablet formulation. The Orodispersible tablet of Loratadine was optimized by Box Behnken Design, where concentrations Kyron T-314, CRP and Pearlitol SD200 were employed and its effect on Disintegration time (DT), Wetting time (WT) and % drug release at 20 min (Q20) was evaluated. Precompression parameters like angle of repose, bulk density, % compressibility, Hausner’s ratio was studies. The different batches of Orodispersable tablets were prepared and evaluated for disintegration time, friability, wetting time and drug release studies. Different batches prepared showed disintegration time in the range of 23 ± 2.52 to 59 ± 2.64, wetting time in between 27± 0.57 to 66.3 ± 3.4, drug release (Q 20) in between 86.1 ± 0.6 to 96.7 ± 0.4 in 20 min., friability less than 1 % and hardness 3.4 to 4.2 Kg/cm2. The optimized formula when compared with marketed product it showed faster disintegration time and rapid drug dissolution in phosphate buffer 6.8. The solid dispersion of Loratadine not only helped improve in solubility but may also help in taste masking. Keywords: Orodispersible tablets, Loratadine, β cyclodextrin Solid dispersion
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Katewongsa, Prachya, and Thawatchai Phaechamud. "Influence of Disintegrant on Properties of Fast Disintegrating Tablet Containing Xylitol." Advanced Materials Research 581-582 (October 2012): 1141–44. http://dx.doi.org/10.4028/www.scientific.net/amr.581-582.1141.

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Disintegrants had influence on disintegration time and dissolution for fast disintegrating tablet (FDTs). Therefore, the purpose of this study was to evaluate the effect of disintegrant type on the characteristics of FDTs. In this research, the tablets were fabricated by direct compression with the compression force of 1.5 tons and using the different disintegrants components (chitin, chitosan, xylitol, microcrystalline celluloses, white bentonite and magnabite F). The physical properties of these tablets were determined. The xylitol tablets were rapidly disintegrated within 7+1 s, whereas that of the others was longer than 30 mins. The tablets containing the mixture of xylitol and other materials were subsequently fabricated since the hardness of the xylitol tablet was very poor. The disintegration time and wetting time of tablets containing 9:1 xylitol:Avicel PH101 was shorter than that of the others. The contact angle of tablets containing xylitol and Avicel PH101 at the ratio of 9:1 was lowest and surface free energy (SFE) of them was highest compared with the other formula. Moreover, scanning electron microscope (SEM) displayed that xylitol and tablets containing 9:1 xylitol:Avicel PH101 had no disordered arrangement, therefore it could promote the disintegrating property effectiently.
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Sharma, Deepak, Gurmeet Singh, Dinesh Kumar, and Mankaran Singh. "Formulation Development and Evaluation of Fast Disintegrating Tablets of Salbutamol Sulphate, Cetirizine Hydrochloride in Combined Pharmaceutical Dosage Form: A New Era in Novel Drug Delivery for Pediatrics and Geriatrics." Journal of Drug Delivery 2015 (February 25, 2015): 1–10. http://dx.doi.org/10.1155/2015/640529.

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The objective of the present study was to prepare the fast disintegrating tablet of Salbutamol Sulphate, Cetirizine Hydrochloride in combined tablet dosage form for respiratory disorders such as bronchitis, asthma, and coughing for pediatrics and geriatrics. The tablets were prepared by direct compression technique. Superdisintegrant such as Sodium Starch Glycolate was optimized as 4% on the basis of least disintegration time. Different binders such as MCC and PVP K-30 were optimized along with optimized superdisintegrant concentration. 1% MCC was selected as optimum binder concentration on the basis of least disintegration time. The tablets were evaluated for hardness, friability, weight variation, wetting time, disintegration time, and drug content uniformity. Optimized formulation was further evaluated by in vitro dissolution test, drug-excipient compatibility, and accelerated stability study. Percent weight variation and content uniformity were within the acceptable limit. The friability was less than 1%. The wetting time and disintegration time were practically good for all formulations. FTIR studies and accelerated stability study showed that there was no interaction between the drug and excipients. It was concluded that, by employing commonly available pharmaceutical excipients such as superdisintegrants, hydrophilic and swellable excipients and proper filler, a fast disintegrating tablet of Salbutamol Sulphate, Cetirizine Hydrochloride in combined tablet dosage form, were formulated successfully with desired characteristics.
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Masih, Ashish, and Ajay Kumar Tiwari. "FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF AMOXYCILLIN TRIHYDRATE AND POTASSIUM CLAVULANATE." International Journal of Current Pharmaceutical Research 9, no. 2 (March 1, 2017): 48. http://dx.doi.org/10.22159/ijcpr.2017v9i2.17385.

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Objective: The present work is aimed to formulate fast dissolving stable tablet formulation a preferred combination of Amoxycillin trihydrate (Beta-lactum antibiotic) and Potassium clavulanate (Beta-lactum inhibitor) by using various super disintegrants.Methods: Fast dissolving tablets are prepared by direct compression method using super disintegrants i.e. sodium starch glycolate, crospovidone, croscarmellose sodium. Aspartame as a sweetener and trusil mango flavor were used to increase palatability. Reduction in the dose of Amoxycillin trihydrate and Potassium clavulanate tablet was possible by developing fast dissolving tablet. Results: The powder blends were subjected to various pre-formulation evaluations such as, tapped density, bulk density, hausner’s ratio, the angle of repose and compressibility index. The prepared Amoxycillin trihydrate and Potassium clavulanate fast dissolving tablets were evaluated for thickness, weight variation, friability, disintegration time, hardness, wetting time and in vitro drug release. All fast dissolving tablet formulations shown uniform weight, hardness and friability data indicates the good mechanical resistance of the fast dissolving tablet. Fast dissolving tablets were disintegrated between 25-50 second and in vitro disintegration time of the best fast disintegrating tablets was found to be 25 second. Conclusion: Amoxycillin trihydrate and Potassium clavulanate fast dissolving tablets were found to be of good quality fulfilling all the needs for fast dissolving tablets. The optimised (F-4) formulation had shown best disintegration time and released profile with a maximum in vitro drug release as compare to marketed preparation at all time intervals of in vitro drug release.
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Dissertations / Theses on the topic "Disintegration time of tablets"

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Badipatla, Visweswararao. "Disintegration of Tablets and Capsules Measured by Isothermal Thermal Mechanical Analysis and Macrophotography." Cleveland State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=csu1315507284.

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Mattsson, Sofia. "Pharmaceutical binders and their function in directly compressed tablets : Mechanistic studies on the effect of dry binders on mechanical strength, pore structure and disintegration of tablets." Doctoral thesis, Uppsala University, Department of Pharmacy, 2000. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-533.

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In this thesis, the strength-enhancing mechanisms of dry binders in direct compression were studied. The systems investigated were binary mixtures containing various compounds and binders. Among the binders used were a series of different molecular weights of polyethylene glycol. The proposed simplified tablet model describing the fracture path in a tablet during strength testing offers an explanation for the increase in tablet strength caused by the binder. The model and results in this thesis indicate that fractures will usually propagate around the tablet particles and through the interparticulate voids during tablet strength testing.

One important characteristic of the binder is its ability to be effectively and evenly distributed through the interparticulate voids in a compound tablet. Characteristics such as high plasticity, low elasticity and a small particle size were associated with a more even distribution and a consequent pronounced effect on pore structure and marked improvement in tablet strength. The strength of tablets containing less plastic binders was governed more by the compactibility of the binder. The tablet porosity, bonding mechanisms and volume reduction mechanisms of the compound also influenced the effect of the binder. For example, the plasticity and particle size of the binder had the most significant effects on tablet strength when the tablet porosity of the com-pound was relatively low. A combination of the plasticity and the compactibility of the binder determined the strength of tablets when the tablet of a compound was more porous. The positive effect of a binder on pore structure and tablet strength resulted in an increase in the disintegration time. Although addition of a superdisintegrant generally improved the disintegration time, the effect was decreased when the formulation included more deformable binders.

The choice of a suitable binder for a tablet formulation requires extensive knowledge of the relative importance of binder properties for enhancing the strength of the tablet and also of the interactions between the various materials constituting a tablet. Thus, the increased knowledge of the functionality of a binder obtained in this thesis enables a more rational approach to tablet formulation.

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Koner, Jasdip. "Formulation strategies and engineering processes for orally disintegrating tablets : the importance of robustness and disintegration." Thesis, Aston University, 2017. http://publications.aston.ac.uk/33600/.

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Orally disintegrating tablets (ODTs) are a dosage form ideal for paediatric or geriatric patients as they disintegrate/disperse within the oral cavity. Direct compression manufacture of ODTs is increasing in popularity due to its cost effectiveness and use of traditional tableting equipment, however excipients are required to fulfil certain requirements to form robust, fast disintegrating tablets. Mannitol is a vital excipient for ODT manufacture due to its high palatability, however its fragmentation behaviour under compression leads to mechanically weak and friable tablets. The work in this thesis aimed to investigate the fragmentation behaviour of milled mannitol, followed by development of preblends to obtain ideal ODT properties without the use of any superdisintegrant. Development of a novel method for ODT disintegration testing was also conducted due to the lack of current techniques that are representative of oral conditions. Mannitol fracture occurred primarily at the (011) crystal plane, which was the most hydrophilic, therefore increasing the wettability of milled mannitol. Resulting ODTs had a faster disintegration time than the unmilled equivalent, with enhancement in compressibility due to increased plastic deformation. Milled mannitol presented a suitable alternative for ODT production compared to current commercial grades, with high mechanical strength and improved disintegration time. Novel optimised ODT preblends were developed with milled mannitol incorporated alongside micro crystalline cellulose (MCC) and silica to aid powder flow. Dry particle coating was also employed to develop an MCC/silica hybrid to enhance MCC properties. Silicified MCC had previously been shown to enhance MCC compression, whilst improving MCC powder flow and reducing lubricant sensitivity. Dry coated MCC was optimised with 1%w/w silica, with ODT disintegration being significantly lower than the spray dried alternative or uncoated MCC, whilst allowing a 40% drug load of a non-compressible API to be formed into a robust fast disintegrating ODT.A novel ODT disintegration method was developed to mimic In Vivo oral conditions. A vastly improved correlation to In Vivo results was observed with the newly developed method, in comparison to the recommended USP tester, with a linear correlation obtained with the new test method compared to the curved dataset gathered with the USP test. Novel preblends were developed utilising dry particle coating, with resultant ODTs showing improved ODT behaviour, with disintegration time being low even without the use of superdisintegrant. To supplement ODT disintegration, novel ODT disintegration time test method was developed and results indicated it was a superior alternative compared to the currently recommend USP test.
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Kindgen, Sarah M. [Verfasser]. "Hydrodynamics and solid dosage form disintegration/dissolution : immediate release tablets and novel in situ polyelectrolyte gastroretentive drug delivery systems / Sarah M. Kindgen." Mainz : Universitätsbibliothek der Johannes Gutenberg-Universität Mainz, 2015. http://d-nb.info/1225749581/34.

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Wall, Alexander. "Characterisation of tablets and roller-compacted ribbons with terahertz time-domain pulsed imaging." Thesis, De Montfort University, 2015. http://hdl.handle.net/2086/11152.

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The pharmaceutical process of dry granulation using roller-compaction (DG/RC) is effectively a non-batch based procedure orientated to deliver a continuous stream of material free of a pre-defined batch-size with reduced plant equipment/scale-up R&D resources and an enhanced work-throughput, particularly suitable for moisture sensitive formulation. The desirable accreditations of DG/RC are many; yet by the nature of a more flexible approach than (i.e. wet-granulation), it must be highly monitored and controlled to accomplish higher-throughput rates and reduced ‘static’ material testing stages. To monitor rapidly and in-line with production, pre-granulated ribbons of RC (which highly correlates to the post milled granulates), terahertz time-domain spectroscopy (TDS) is used to elucidate the key physical attributes of post-compression density and thickness uniformity, key to end-product consistency. Invariably a great number of conditions apply to DG/RC (viz: System design, material characteristics, environmental and unit configuration), although widely regarded as the key processing parameters (PP’s) are roll-pressure and roll-gap [1-4]. The target of the study is to derive a strategy to position TDS as PAT to DG/RC. Two terahertz time-domain TD methods of a conventional transmission setup and reflection (TPI) THz analysis are used on standards of glass slides for verifying the interpretational foundations of the TD methods. Achieving RI/thickness error-discrepancies +2.2 to -0.4% c.f. literature ([150]) values provides foundations to test the solid-fraction ratios of pharma tablets with regard to RI’s being surrogate values to SF/path-length (R2 = 1). Combining transmission principles to the portion of reflected EMR removes the pre-requisite for RI or path-length knowledge, giving +1.5 to +2.4% RI agreement (vs. frequency-domain attained results) thus enabling thickness estimations to be above 95% against physical micrometre judgement in all models. Augmentation of the TD methods, refined in Experimental chapter 2 ,then chiefly focuses on TPI as the principle THz-TD method (as the most ideal tool for PAT) for adopting the RI measures for ribbon uniformity analysis in Experimental chapter 4 in an off-line environment again resulting in RI and thicknesses < 5 % error of known parameters of thickness and further use of RI as a proxy porosity equivalent to gas pycnometry. Elucidated in the work are the limitations encountered with tablets and RC’s, data interpretation of industrial considerations. Experimental chapter 3 diverges from RI to differentiate thickness in-order to assess the FD transmission for non-destructive mechanical assessment. This demonstrates a clear relationship between compaction force and the surrogate value for density, following a linear trend below a certain threshold of force. The ‘threshold’ value is observed for less massive tablets, and concluded is that the mechanistic interplay and permanent (plastic) consolidation is greater in instances where compaction-force increases proportionally with target-fill weights, and thus the various behaviour of MCC to stress.
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Zaheer, Kamran [Verfasser]. "Evaluation of formulation and processing factors on the disintegration and dissolution of immediate release tablets in fed state : formulation strategy towards minimizing viscosity mediated negative food effect / Kamran Zaheer." Mainz : Universitätsbibliothek Mainz, 2018. http://d-nb.info/1159797374/34.

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Ericsson, Duffy Mikael. "DRAWN TO LIFE: Exploring real-time manipulation of the digitally represented surface in comics on smartphones and tablets." Thesis, Malmö högskola, Fakulteten för kultur och samhälle (KS), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-23439.

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This research thesis is an exploration into what possibilities lie beyond the representation of analog material when it transcends into the digital realm. Specifically, how printed comics can be altered in realtime by creator- allowed user interaction, when adapted for presentation within the digital sphere of mobile smartphones and computer tablets. Using legacy computer-game techniques like parallax scrolling with modern digital layer filters, device sensors and applying them in realtime to the comic creators digitally layered content, alternative forms of presentation arise.This is an investigation into the comic creator’s will of allowing possibilities of added depth perception, interactivity and alternative visual narratives in their comic, manga or graphic novels when employing new techniques based on sensor data input from a reader, like accelerometer-, gyroscope- or eye-tracking sensors. Several different techniques are evaluated. The focus is mainly on the context of creators of comics or manga who use digital tools and layer compositions when producing their work. Several aspects of the user-centered experience are also explored.Although mainly an interaction design project, most of the design methods are used from a service design approach, emphasizing co-design techniques like interviews, observations and user tests. The results are digital prototypes and proof-of-concepts featuring technology tests that support final design conclusions.The results will show both enthusiasm and reluctance from test subjects towards the new technologies presented. The professional craft of comic, manga and graphic novel creation has a deeply rooted aesthetic and production cycle in its history of the printed form. It could be difficult to alter its standard, reverence and nostalgia in the eyes of its readers and creators, when pursuing the digital format and narrative possibilities of the future. A video explaining the project’s “Drawn To Life” technology is available online.
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Al, Alaween Wafa'. "A new framework for right-first-time production of granules and tablets : a systems engineering approach to modelling and optimization." Thesis, University of Sheffield, 2018. http://etheses.whiterose.ac.uk/19215/.

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Ferreira, Juliana Borges. "Simulações da SAR em virtude da exposição por tablets operados próximo à cabeça." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2016. http://hdl.handle.net/10183/143369.

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A grande maioria da população mundial está crescentemente exposta à radiação eletromagnética proveniente de fontes que muitas vezes estão localizadas nas proximidades do corpo. A radiação eletromagnética é considerada um agente possivelmente cancerígeno para as pessoas, classificação 2B indicada pela Organização Mundial da Saúde-OMS (WHO/IARC, 2011). Devido às preocupações em relação aos riscos associados a esta exposição existem normas que recomendam os valores máximos de exposição permitidos (ICNIRP, 1998; FCC, 2001). A correta avaliação das doses de radiação é, portanto, relevante. Este trabalho tem a finalidade de avaliar o impacto dos resultados do cálculo da dose da Taxa de Absorção Específica (SAR) em usuários expostos a radiação por tablets operando na faixa de radiocomunicações Wi-fi. Os três modelos existentes de cabeça humana utilizados serão um manequim homogêneo SAM phantom e dois modelos de cabeça realistas heterogêneos: um adulto masculino e uma criança masculina. Será também utilizado nas simulações um modelo masculino de criança que foi desenvolvido através de imagens de tomografia computadorizada (TC) pelo processo de segmentação feito no software AMIRA. Será utilizado um modelo genérico de tablet. Os parâmetros dosimétricos usados para simulação da SAR serão computados pelo software SEMCAD X que é baseado no Método das Diferenças Finitas no Domínio do Tempo (FDTD). Será criado também um código do Método FDTD através do software MATLAB que servirá para a escolha dos parâmetros do SEMCAD X. A distância entre o tablet e os modelos de cabeças varia de 50 mm a 300 mm. Os resultados da SAR serão comparados com os limites de exposição recomendados pelas normas internacionais. Também serão simuladas diferentes posições da antena no tablet. Da análise dos resultados foi constatado que os valores de SAR são muito baixos e todos os resultados ficaram dentro dos limites do psSAR recomendados pela FCC de 1,6 W/kg em cada 1 g de tecido e de 2 W/kg em cada 10 g de tecido estabelecidos pela ICNIRP. Comparando os valores de SAR do modelo SAM com o modelo DUKE, o modelo SAM se mostra conservador, porém quando a comparação é feita com as crianças o SAM deixa de ser conservador.
The vast majority of the world population is increasingly exposed to electromagnetic radiation from sources which are often located near to the body. Electromagnetic radiation is considered a possible carcinogen for people, classification 2B indicated by the World Health Organization-WHO (WHO/IARC, 2011). Due to concerns regarding the risks associated with this exposition there are regulations suggesting maximum allowed exposure values (ICNIRP, 1998; FCC, 2001). The correct evaluation of radiation doses is therefore relevant. This work aims to assess the impact of the results of the calculation of Specific Absorption Rate dose (SAR) in users exposed to radiation from tablets operating in the Wi-fi band. The three existing models of human head used are a homogeneous dummy SAM phantom and two heterogeneous realistic head models: a male adult and a male child. It will also be used in the simulations a male child model which was developed from computed tomography (CT) imaging using the AMIRA software for the segmentation process. A generic model of tablet is used. Dosimetric parameters used for simulation of the SAR are computed using the SEMCAD X software which is based on the Finite Difference Method in Time Domain (FDTD). A FDTD code was developed using the MATLAB software in order to help to choose the input SEMCAD X parameters. The distances between the tablet and the head of the models varies from 50 mm to 300 mm. SAR results are compared with the exposure limits recommended by international standards. Different antenna positions on the tablet are simulated too. Examining the results it was found that the SAR values are very low and all results are within the psSAR limits recommended by FCC (1,6 W/kg averaged over 1 g of tissue) and by ICNIRP (2 W/kg in 10 g of tissue). Comparing the SAR in the SAM model with the SAR in the DUKE model, the SAM model shows to be conservative. However, when compared with the children, the SAM is not conservative.
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Hall, Krystyn Alter. "Chemical 'Fingerprinting' and Identification of Unknowns in Counterfeit Artesunate Antimalarial Tablets from Southeast Asia by Liquid Chromatography/Time-of-flight Mass Spectrometry." Thesis, Available online, Georgia Institute of Technology, 2005, 2005. http://etd.gatech.edu/theses/available/etd-11252005-120253/.

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Books on the topic "Disintegration time of tablets"

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Milliken, Randall. A time of little choice: The disintegration of tribal culture in the San Francisco Bay Area, 1769-1810. Menlo Park, CA: Malki Museum, 2009.

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Milliken, Randall. A time of little choice: The disintegration of tribal culture in the San Francisco Bay Area, 1769-1810. Menlo Park, CA: Malki Museum, 2009.

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Milliken, Randall. A time of little choice: The disintegration of tribal culture in the San Francisco Bay area, 1769-1810. Menlo Park, CA: Ballena Press, 1995.

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Milliken, Randall. A time of little choice: The disintegration of tribal culture in the San Francisco Bay area, 1769-1810. Menlo Park, CA: Malki-Ballena Press, 2009.

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Maiocchi, Massimo, and Giuseppe Visicato. Administration at Girsu in Gudea’s Time. Venice: Fondazione Università Ca’ Foscari, 2020. http://dx.doi.org/10.30687/978-88-6969-412-7.

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The book offers the edition of all presently known administrative texts from Girsu (modern Telloh, Iraq), dated to the Lagash II period (XXII century BCE). The evidence consists of roughly 600 cuneiform tablets – including 34 published here for the first time – that are presently scattered over various collections (mostly in London, Paris, Istanbul, Strasbourg, Dublin). They are of enormous historical value, in that they provide unique information for the reconstruction of urbanization, political affairs, and social developments in Mesopotamia at the time of Gudea, the most notable figure of his dynasty, and of his son Urningirsu II.
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Maihack, Mike. Secret Of The Time Tablets. Turtleback Books, 2016.

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Maihack, Mike. Cleopatra in space: Secrets of the time tablets. 2016.

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Cleopatra in space. Book three, Secret of the time tablets. Graphix, an imprint of Scholastic, 2016.

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Kämmerer, Jörn Axel, Markus Kotzur, and Jacques Ziller, eds. Integration und Desintegration in Europa | Integration and Desintegration in Europe | Intégration et Désintégration en Europe. Nomos Verlagsgesellschaft mbH & Co. KG, 2019. http://dx.doi.org/10.5771/9783748902225.

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The EU’s vulnerability to crises is not a novelty, but disintegrative trends have reached a new quality. The financial and fiscal crisis shook the Union, which had just been consolidated by the Lisbon Treaty, to its foundations. The refugee crisis becomes a heavy test of European solidarity. For the first time, a member state, the United Kingdom, wants to leave the Union and in doing so, as at least the Brexiteers argue, regain its sovereignty. Even the member states themselves are not spared from moments of disintegration. One might think of the secessionist movements in Catalonia or Scotland etc. Against this background, the SIPE Congress in Hamburg has brought together high-ranking experts from all over Europe in order to explore the tension between integration and disintegration, as well as Europe’s prospects of being “united in diversity”. The discussions paint a differentiated overall panorama of the constantly challenged integration project. With contributions by Francisco Balaguer Callejón, Roland Bieber, Jernej Letnar Černič, Jenö Czuczai, Daria de Pretis, Ian Forrester, Ece Göztepe, Ana Maria Guerra Martins, Christian Heitsch, Stefan Herms, Ann-Kathrin Kaufhold, Panos Kazakos, Markus Kotzur, Clifford Larsen, Friedrich-Joachim Mehmel, Eleftheria Neframi, Dimitrios Parashu, Argelia Queralt Jiménez, Andrea Romano, Tilman Repgen, Sebastian Scholz, Christian Starck
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Vasilopoulou, Sofia. The Radical Right and Euroskepticism. Edited by Jens Rydgren. Oxford University Press, 2018. http://dx.doi.org/10.1093/oxfordhb/9780190274559.013.7.

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This chapter examines the role that the European Union (EU) issue plays in radical right party agendas. It shows that, despite the fact that radical right parties tend to adopt dissimilar positions on the principle, practice, and future of European integration, they all tend to criticize the EU from a predominantly sovereignty-based perspective justified on ethnocultural grounds. The EU is portrayed as posing a threat to national sovereignty, its policies dismantling the state and its territory, as well as being responsible for the cultural disintegration of Europe and its nation-states. The analysis of EU issue positions and salience over time suggests that—despite variations—radical right parties engage in EU issue competition not only by adopting extreme positions but also by increasingly emphasizing these positions over time.
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Book chapters on the topic "Disintegration time of tablets"

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Houseknecht, Justin B. "Just-in-Time Teaching Organic Chemistry with iPad Tablets." In ACS Symposium Series, 81–92. Washington, DC: American Chemical Society, 2016. http://dx.doi.org/10.1021/bk-2016-1228.ch005.

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Bagchi, Partha, and Ajit M. Srivastava. "Disintegration of Quarkonia in QGP Due to Time Dependent Potential." In Springer Proceedings in Physics, 135–39. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-25619-1_21.

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Lambert, N., P. Van Aken, I. Smets, and R. Dewil. "Effect of Sludge Retention Time on the Efficiency of Excess Sludge Reduction by Ultrasonic Disintegration." In Lecture Notes in Civil Engineering, 131–37. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-58421-8_20.

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Khan, Amjad, Shabnam Nazir, Hamad S. Alyami, and Aman Ullah. "SeDeM-ODT Expert System: A Solution to Challenges in Characterization of Pharmaceutical Powders and Powdered Material." In Advanced Functional Materials. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.92444.

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In the field of pharmaceutical sciences, material characterization has been a focus of research as properties of the powder ingredients govern characteristics of the finished dosage form. It has been a tedious and time-consuming job to develop a correlation between the characteristics of powder material and final dosage form. Extensive experimentation is carried out at different stages of formulation development to optimize the final blend and produce a product fulfilling official requirements. Various approaches have been applied for the purpose with varying degree of applications. SeDeM-ODT expert system is a novel pre-formulation technique developed for characterization of powder material of varying nature. Experimental and quantitative determination of various parameters provides a basis for SeDeM-ODT expert system. The system predicts suitability of powder material (APIs and excipients) for tablet preparation by direct compression technology and disintegration behavior of the resultant dosage form. It provides a basis for selection of excipients, both quantitatively and qualitatively. The present study covers area of powder characterization at pre-formulation level of pharmaceutical product development. SeDeM-ODT expert system reduces lead time for pre-formulation studies and provides formulations with minimum number of excipients. SeDeM-ODT expert system has been successfully applied for material characterization (APIs and excipients) before processing and after processing.
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Vandecasteele, Carlo, Luc Van Gool, Karel Van Lerberghe, Johan Van Rompay, and Patrick Wambacq. "Digitising Cuneiform Tablets." In Images and Artefacts of the Ancient World. British Academy, 2005. http://dx.doi.org/10.5871/bacad/9780197262962.003.0004.

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In 1850, ‘Assyriology’, or the science of reading and interpreting cuneiform, was created. During this period, historians travelled to the Middle East and spent years copying cuneiform tablets. Now, at the beginning of the third millennium AD, not much has changed. Historians still rely on epigraphy which employs the copying of inscriptions and texts by hand. This method is highly subjective, tedious and time-consuming. As Middle Eastern antiquities departments do not allow the export of these tablets, historians and scholars are faced with the challenge of producing more efficient field methods. This chapter discusses a new method of recording the information taken from cuneiform tablets using digitizing. Digital imaging uses a camera wherein the picture captured is linked to a laptop which runs an image processing algorithm program to obtain the desired results. An enhancement method is then applied to improve the quality of the image. Digitizing cuneiform tablets provides historians a working document with legibility of 90 to 95 per cent. Aside from its relatively efficiency, digital imaging can also allow for the registering of various tablets in one excavation season and can be employed in the digital registration of all sealings such as pottery sherds, and fingerprints on clay vessels.
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Mullan, Killian. "Time for Technology." In A Child's Day, 117–44. Policy Press, 2020. http://dx.doi.org/10.1332/policypress/9781529201697.003.0005.

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This chapter evaluates children's time using technology. Technological change has dramatically altered not only the overall amount of time children spend in screen-based activities, but also the composition of this time. The time children spend watching TV decreased substantially and they are spending more time using computers and playing video games. In addition, children are now spending a substantial amount of time using devices such as smartphones and tablets. Children can use these devices at various locations and during times also spent doing various screen-based and non-screen activities. Children's time using devices appears to have had little impact on the time they spend in other activities, including physical activities. There has been, however, dramatic change in elements of the social context of children's daily lives that may be connected to the time they spend using mobile devices.
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"11. Situational Politics: Paradoxical Time Horizons Between Desynchronization and Disintegration." In Social Acceleration, 251–76. Columbia University Press, 2013. http://dx.doi.org/10.7312/rosa14834-015.

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Gao, Shijia, William Yeoh, Siew Fan Wong, and Edgar Alexander Bruno Kautzner. "Factors Influencing Managers' Use of Mobile Tablets." In Advances in Business Strategy and Competitive Advantage, 202–17. IGI Global, 2019. http://dx.doi.org/10.4018/978-1-5225-5718-0.ch011.

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In recent years mobile tablets are being used by many managers. Yet hitherto there is a lack of research on managerial use of the new mobile technology. Hence, this study aims to explore the factors that influence the use of mobile tablets by managers and how mobile tablets impact the use of other digital devices. Semi-structured interviews were conducted with a panel of mid- to high-level managers who had incorporated mobile tablets into their work routine. The findings reveal that mobile tablets are suitable for managerial tasks due to nine main factors: non-routineness, collaborative nature, time-critical, information-centric, mobility, user friendliness of the interface, reliability, connectivity, and autonomy. Also, the use of mobile tablets has significant impact on the use of other digital devices as well as traditional manual process of using pens and papers. This study fills in the research gap and provides a foundation to help managers establish a business case for or against mobile tablet use.
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Clancy, Donald, Jeegna Patel-Jones, and Gordon Hutton. "Accelerated Stability Modeling: Investigation of Disintegration Time of a Drug Product With Sodium Bicarbonate." In Accelerated Predictive Stability, 403–10. Elsevier, 2018. http://dx.doi.org/10.1016/b978-0-12-802786-8.00019-x.

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Pomfret, Richard. "Regional Problems and Opportunities." In The Central Asian Economies in the Twenty-First Century, 201–29. Princeton University Press, 2019. http://dx.doi.org/10.23943/princeton/9780691182216.003.0009.

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This chapter analyzes alternative strategies—multilateral and regional—pursued by the Central Asian countries to integrate into a wider economic circle, emphasizing the shift from being part of the highly integrated Soviet economy to regional disintegration in the 1990s and early 2000s and then, after 2006, steps towards greater cooperation and integration. In the 1990s and 2000s, despite the actual multilateralism, only the Kyrgyz Republic joined the World Trade Organization. At the same time, a number of regional agreements were signed, both among the Central Asian countries and between Central Asian countries and their neighbors, although none had much influence, until the Eurasian Economic Union was constructed after 2009. Meanwhile, high costs of international trade in Central Asia are a symptom and a cause of regional disintegration.
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Conference papers on the topic "Disintegration time of tablets"

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Funkhouser, Cyrus, Sogra Fathima Barakh Ali, Laura Richardson, Ziyaur Rahman, Mansoor Khan, and Mathew Kuttolamadom. "Thermal Influence on Printlet Quality in the Selective Laser Sintering of Pharmaceutical Formulations." In ASME 2020 15th International Manufacturing Science and Engineering Conference. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/msec2020-8508.

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Abstract The objective of this research is to determine the influence of temperature on the mechanical and dissolution performance of pharmaceutical printlets (tablets) fabricated via selective laser sintering (SLS) additive manufacturing. When compared to traditional high-volume pharmaceutical manufacturing, additive manufacturing has the potential to effectively cater to personalized and just-in-time medicine. Among additive manufacturing methods, SLS has the advantage of not needing to reconstitute the drug(s) with other liquids or powders, as well as the ability to tailor certain location-specific properties via process parameter control. One of the critical parameters that affect the printlet quality is the temperature during the printing process. To explore the thermal effects, two separate experiment sets were conducted. First, process parameters including chamber temperature were studied based on a partial-factorial design of experiments, and their effects on parameters such as weight, hardness, structural disintegration and dissolution rates studied. Next, a smaller scale study was conducted to correlate surface temperatures with structural integrity. Results showed the beneficial and detrimental effects of operating at chamber and bed temperature ranges, in relation to the polymer percentage and melting point. A certain minimum energy density needed to be imparted onto the powder mixture combinations (resulting in a certain surface temperature) for proper fusion and performance of the printlets. This work served to investigate and show the potential of using SLS to reliably fabricate pharmaceutical formulations.
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Bagchi, Partha. "Disintegration of quarkonia in QGP due to time dependent potential." In 9th International Workshop on Critical Point and Onset of Deconfinement. Trieste, Italy: Sissa Medialab, 2015. http://dx.doi.org/10.22323/1.217.0050.

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Pudjiastuti, Pratiwi, Esti Hendradi, Siti Wafiroh, Muji Harsini, and Handoko Darmokoesoemo. "The effect of glicerol and sorbitol plasticizers toward disintegration time of phyto-capsules." In 5TH INTERNATIONAL CONFERENCE AND WORKSHOP ON BASIC AND APPLIED SCIENCES (ICOWOBAS 2015). AIP Publishing LLC, 2016. http://dx.doi.org/10.1063/1.4943318.

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Prentice, Paul, Michael P. MacDonald, Alfred Cuschieri, Kishan Dholakia, and Paul Campbell. "Real time observation of the ultrasound stimulated disintegration of optically trapped microbubbles in proximity to biological cells." In Optics & Photonics 2005, edited by Kishan Dholakia and Gabriel C. Spalding. SPIE, 2005. http://dx.doi.org/10.1117/12.615012.

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Nativivat, V., L. Zhao, L. F. Gladden, and J. A. Zeitler. "A novel method to monitor the storage stability of pharmaceutical tablets using terahertz time-domain spectroscopy." In 2009 34th International Conference on Infrared, Millimeter, and Terahertz Waves (IORMMW-THz 2009). IEEE, 2009. http://dx.doi.org/10.1109/icimw.2009.5324640.

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Yoshinaga, Takao. "Encapsulation and Disintegration of a Gas-Cored Annular Liquid Jet." In ASME-JSME-KSME 2011 Joint Fluids Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/ajk2011-10040.

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Breakup and encapsulation phenomena are analytically investigated for a gas-cored compound liquid jet which consists of an inviscid and incompressible core gas and surrounding annular liquid. Applying the long wave approximation to both core and annular phases, a set of reduced nonlinear equations is derived for large deformations of the jet. Breakup of the jet is numerically examined in the reduced equations when the jet is semi-infinite and sinusoidal disturbances are fed at the end of the jet. It is found that there exit the most unstable frequencies of disturbances giving the shortest breakup time, which increase as the increase of input amplitudes and velocity ratios of the core to the annular phases, while increase or decrease depending upon the Weber numbers based on the annular phase. For small and medium Weber numbers, it is shown that the jet breaks up by pinching of the core phase and the capsule formation periods and sizes can be determined by the most unstable frequencies, which well agree with the results in the previous experiment and the existing phenomenological model. On the other hand, it is also shown for large Weber numbers that the jet breaks up by disintegration of the annular phase and fails to encapsulate the core gas.
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Kamran, Faisal, Otto Højager Attermann Nielsen, Stefan Andersson-Engels, and Dmitry Khoptyar. "Broadband photon time of flight spectroscopy: advanced spectroscopic analysis for ensuring safety and performance of pharmaceutical tablets." In Asia Communications and Photonics Conference. Washington, D.C.: OSA, 2013. http://dx.doi.org/10.1364/acpc.2013.af3k.4.

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Kamran, Faisal, Otto Højager Attermann Nielsen, Stefan Andersson-Engels, and Dmitry Khoptyar. "Broadband photon time of flight spectroscopy: advanced spectroscopic analysis for ensuring safety and performance of pharmaceutical tablets." In Asia Communications and Photonics Conference. Washington, D.C.: OSA, 2013. http://dx.doi.org/10.1364/acp.2013.af3k.4.

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Akseki, Ilgaz, Christopher F. Libordi, and Cetin Cetinkaya. "Non-Contact Acoustic Techniques for Drug Tablet Monitoring." In ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-13940.

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Quality assurance monitoring and material characterization is of great importance in the pharmaceutical industry. If the tablet coating and/or core are defective, the desired dose delivery and bioavailability can be compromised. Tablet coatings serve a wide variety of purposes such as regulating controlled release of active ingredients in the body, contributing to the bioavailability of a particular drug or combination of drugs, during certain times and locations within the body, protecting the stomach from high concentrations of active ingredients, extending the shelf life by protecting the ingredients from degradation from moisture and oxygen, and improving the tablet's visual appeal. If a coating layer is non-uniform and/or contains surface or sub-surface defects, the desired dose delivery and bioavailability can be compromised. The Food and Drug Administration has initiated a program named the Process Analytical Technology (PAT) in order to ensure efficient quality monitoring at each stage of the manufacturing process by the integration of analytical systems into the procedure. Improving consistency and predictability of tablet action by improving quality and uniformity of tablets is required. An ideal technique for quality monitoring would be non-invasive, non-destructive, rapid, intrinsically safe and cost-effective. The objective of the current investigation was to develop, non-contact/non-destructive techniques for monitoring and evaluating drug tablets for mechanical defects such as coating layer irregularities, internal cracks and delamination using a laser-acoustic approach. In the proposed system, a pulsed laser is utilized to generate non-contact mechanical excitations and interferometric detection of transient vibrations of the drug tablets. Three novel methods to excite vibration in drug tablets are developed and employed: (i) a vibration plate excited by a pulsed-laser, (ii) pulsed laser-induced plasma expansion, and (iii) an air-coupled acoustic transducer. Nanometer-scale transient surface displacements of the drug tablets are measured using the laser interferometer. Signal processing techniques are then applied to these transient displacement responses to differentiate the defective tablets from the nominal ones. From the analysis of frequency spectra and the time-frequency spectrograms obtained under both mechanisms, it can be concluded that defective tablets can be effectively differentiated from the nominal ones.
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Glahn, A., S. Busam, M. F. Blair, K. L. Allard, and S. Wittig. "Droplet Generation by Disintegration of Oil Films at the Rim of a Rotating Disk." In ASME Turbo Expo 2000: Power for Land, Sea, and Air. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/2000-gt-0279.

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A fundamental study has been performed to examine oil film disintegration mechanisms at the rim of a rotating disk. The configuration investigated is an abstraction of one of the droplet generation sources in an aero-engine bearing compartment. The paper aims to contribute to both the determination of directly applicable droplet characteristics and the establishment of a data-base that can be used for the development of droplet generation models. The near-term objectives of the study are (i) to identify disintegration modes relevant with respect to aero-engine bearing compartment operating conditions, (ii) to determine droplet sizes under those operating conditions, and (iii) to measure individual droplet diameter/velocity relationships. The long-term objective is to incorporate this information into advanced CFD-based design tools. The disintegration modes identified here were similar to previously reported flow regimes generated by rotary atomizers (Lefebvre, 1989). However, slightly different transition characteristics are documented for the turbine oil considered here, indicating a transition occurring at either higher speeds or higher flow rates. Droplet diameters and velocities are presented for relevant bearing compartment conditions. In this mode, droplet diameters appear to be insensitive to the volume flow rate, but show a finer atomization for increasing rotational speeds. Eventually a speed is reached beyond which no further droplet diameter reduction is obtained. For the first time, size class resolved droplet velocities are presented. A variation of operating parameters at a constant radial location does not have a significant impact on either the normalized droplet velocity or the flow angle. Radial traverses show a decrease of the droplet velocity with increasing distance from the rim of the disk and a transition from a more tangentially orientated droplet trajectory to a more radial motion.
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