Academic literature on the topic 'Disoluce'

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Journal articles on the topic "Disoluce"

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Syofyan, Syofyan, Tri Yanuarto, and Maria Dona Octavia. "Pengaruh Kombinasi Magnesium Stearat dan Talkum sebagai Lubrikan terhadap Profil Disolusi Tablet Ibuprofen." Jurnal Sains Farmasi & Klinis 1, no. 2 (2015): 195. http://dx.doi.org/10.29208/jsfk.2015.1.2.35.

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Telah dilakukan penelitian tentang pengaruh kombinasi magnesium stearat dan talkum sebagai lubrikan terhadap profil disolusi tablet Ibuprofen. Dari ketiga formula dibuat tablet Ibuprofen dengan metoda granulasi basah. Evaluasi tablet meliputi keseragaman ukuran, keseragaman bobot, kekerasan tablet, waktu hancur, kerapuhan tablet, penetapan kadar dan disolusi. Hasil persen terdisolusi menit ke 60 menunjukkan bahwa disolusi rata-rata berturut-turut adalah 95,7209%, 97,6474% dan 99,9373%. Dan untuk hasil efisiensi disolusi pada menit ke 60 masing-masing formula adalah 82,1089%, 87,5888% dan 90,76
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Anggraini, Deni. "STUDI KOMPARATIF LAJU DISOLUSI TABLET ASAM MEFENAMAT GENERIK BERMEREK YANG BEREDAR DIKOTA PEKANBARU." SCIENTIA : Jurnal Farmasi dan Kesehatan 10, no. 2 (2020): 160. http://dx.doi.org/10.36434/scientia.v10i2.319.

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Asam mefenamat adalah obat analgesik golongan NSAIDs (Non Steroidal Anti-inflammatory Drugs) termasuk dalam kelas II Biopharmaceutical Classification System (BCS) dengan kelarutan rendah dan permeabilitas yang tinggi. Uji disolusi merupakan suatu parameter yang penting dalam pengembangan produk dan pengendalian mutu sediaan obat yang didasarkan pada pengukuran kecepatan pelepasan dan melarut zat aktif dari sediaannya. Terdapat korelasi antara laju disolusi dengan ketersediaan hayati obat. Laju disolusi juga dipengaruhi oleh faktor formulasi. Faktor formulasi biasanya juga akan mempengaruhi har
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Binarjo, Annas, and Husnul Khotimah. "Disolusi Kapsul Dispersi Padat Piroksikam-PEG 6000 Selama Penyimpanan." Indonesian Journal of Pharmaceutical Science and Technology 4, no. 1 (2017): 18. http://dx.doi.org/10.15416/ijpst.v4i1.7933.

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Kelarutan piroksikam yang rendah mempengaruhi laju disolusi sebagai penentu bioavaibilitas. Pembuatan dispersi padat dengan piroksikam-polietilenglikol dapan meningkatkan laju disolusinya. Tujuan penelitian ini adalah untuk mengetahui pengaruh pembentukan dispersi padat piroksikam- polietilenglikol 6000 (PEG 6000) terhadap laju disolusi kapsul piroksikam selama 1 bulan penyimpanan. Rekristal piroksikam (R) dan dispersi padat piroksikam-PEG 6000 (DP) dibuat dengan metode pelarut menggunakan campuan aseton-etanol (1:1), keduanya bersama dengan piroksikam tanpa modifikasi (P) dikapsul dan disimpa
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Zaini, Erizal, Vike Zulia Putri, Maria Dona Octavia, and Friardi Ismed. "Peningkatan Laju Disolusi Dispersi Padat Amorf Genistein dengan PVP K-30." Jurnal Sains Farmasi & Klinis 4, no. 1 (2017): 67. http://dx.doi.org/10.29208/jsfk.2017.4.1.197.

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Sistem dispersi padat amorf senyawa obat yang sukar larut air genistein dalam PVP K-30 dibuat dengan metode penguapan pelarut menggunakan pelarut metanol. Sistem dispersi padat dibuat dengan variasi perbandingan obat : polimer 2:1, 1:1 dan 1:2 b/b. Sifat padatan serbuk sistem dispersi padat dievaluasi dengan metode analisa difraksi sinar-X, termal DSC, spektrokopik FT-IR dan mikroskopik SEM. Profil disolusi dilakukan dalam medium air suling dengan alat uji disolusi tipe II USP. Hasil analisa difraksi sinar-X, termal DSC dan mikroskopik SEM, fase kristalin genistein mengalami penurunan derajat
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Zaini, Erizal, Netty Novitasari, and Maria Dona Octavia. "Pembentukan Sistem Dispersi Padat Amorf Azitromisin Dihidrat dengan Hikroksipropil Metilselulosa (HPMC)." Jurnal Sains Farmasi & Klinis 3, no. 2 (2017): 165. http://dx.doi.org/10.29208/jsfk.2017.3.2.140.

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Tujuan penelitian ini untuk mengembangkan sistem dispersi padat azitromisin dihidrat dengan pembawa hidroksipropil metilselulosa E5 LV agar laju disolusi azitromisin dihidrat meningkat. Dispersi padat amorf dibuat dengan metode pelarutan pada perbandingan obat : polimer 1:1; 1:2 and 2:1. Sifat padatan dispersi padat amorf dievaluasi dengan analisa difraksi sinar-X, mikroskopik SEM dan spekroskopi FT-IR. Lebih lanjut, profil laju disolusi dilakukan dengan alat uji disolusi tipe II USP. Menurut analisa difraksi sinar-X, azitromisin dihidrat mengalami transformasi sebagian dari fase kristalin ke
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Rosaini, Henni, Yolla Erman Novita Sari, Indra Makmur, Auzal Halim, and Wahyu Margi Sidoretno. "KARAKTERISASI SIFAT FISIKOKIMIA SISTEM DISPERSI PADAT NIMODIPIN DENGAN POLOXAMER 188 MENGGUNAKAN METODE PENGGILINGAN BERSAMA." JOPS (Journal Of Pharmacy and Science) 4, no. 2 (2020): 18–26. http://dx.doi.org/10.36341/jops.v4i2.1351.

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Nimodipin merupakan salah satu senyawa yang tidak larut dalam air dan termasuk ke dalam Biopharmaceutical Classification System (BCS) kelas II. Sistem dispersi padat adalah campuran yang homogen dari satu atau lebih bahan aktif dalam matriks yang inert dengan tujuan meningkatkan bioavaibilitas dari bahan obat yang sukar larut. Penelitian ini bertujuan untuk melihat pengaruh penambahan poloxamer 188 terhadap sifat fisikokimia dan profil disolusi dari nimodipin yang dibuat dengan metode penggilingan bersama. Perbandingan nimodipin dengan poloxamer 188 untuk F1, F2, F3 berturut – turut adalah 1:9
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Sari, Yeni Novita, Erizal Zaini, and Friardi Ismed. "Peningkatan Laju Disolusi Piperine dengan Pembentukan Multikomponen Kristal Menggunakan Asam Nikotinat." Jurnal Sains Farmasi & Klinis 6, no. 2 (2019): 180. http://dx.doi.org/10.25077/jsfk.6.2.180-185.2019.

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Tujuan penelitian ini adalah untuk meningkatkan laju disolusi piperin dengan pembentukan multikomponen kristal piperin dan asam nikotinat (1:1) dengan metode pelarutan menggunakan pelarut etanol. Multikomponen kristal dikarakterisasi sifat padatannya dengan Difraksi sinar-X, analisa termal Differential Scaning Calorimetry (DSC), spektroskopi FT-IR, analisa mikroskopik Scanning Electron Microscopy (SEM), uji kelarutan dan profil laju disolusi menggunakan Aparatus USP 2. Dari penelitian serbuk multikomponen kristal piperin-asam nikotinat diperoleh hasil pola difraksi sinar-X menunjukkan puncak d
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Agustin, Rini, and Hestiary Ratih. "Profil Disolusi Tablet Sustained Release Natrium Diklofenak dengan Menggunakan Matriks Metolose 90 SH 4000." Jurnal Sains Farmasi & Klinis 1, no. 2 (2015): 176. http://dx.doi.org/10.29208/jsfk.2015.1.2.33.

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Natrium diklofenak (Na-diklofenak) adalah obat anti inflamasi non steroid yang umumnya digunakan untuk penderita radang sendi. Namun, waktu paruh yang pendek sekitar 1-2 jam menyebabkan obat diberikan berulang kali dalam interval waktu yang pendek untuk pemberian secara oral. Oleh karena itu, tujuan penelitian ini yaitu memformulasi Na-diklofenak tablet sustained release menggunakan metolose 90 SH 4000 sebagai matriks. Untuk melihat pengaruh metolose 90 SH 4000 terhadap profil disolusi Na-diklofenak tablet sustained release, metolose 90 SH 4000 ditambahkan dengan perbandingan 0% (F0), 5% (F1),
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HARTESI, HARTESI, Lia Anggresani, Desi Sagita, and Julia Ambar Sari. "Pembentukan Pembentukan Kompleks Inklusi Ibuprofen Kombinasi Polimer beta siklodekstrin dan Hydroxypropyl Metylcelulose Menggunakan Teknik Kneading." Riset Informasi Kesehatan 7, no. 1 (2018): 99. http://dx.doi.org/10.30644/rik.v7i1.139.

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Latar Belakang : Ibuprofen termasuk kedalam BCS kelas II yaitu memiliki kelarutan yang rendah tetapi memiliki permeabilitas tinggi.Berdasarkan literatur kombinasi beta siklodekstrin dan Hidroksipropil Metilselulosa dapat meningkatkan kelarutan.
 Tujuan :Untuk meningkatkan laju disolusi dari ibuprofen dalam bentuk kompleks inklusi dengan kombinasi beta siklodekstrin dan Hidroksipropil Metilselulosa
 Metoda :Menggunakan teknik kneading. Ibuprofen di buat dengan 4 formula dengan perbandingan beta siklodekstrin F1 (1:0,5), F2 (1:1), F3 (1:1.5), dan F4 (1:2) dan penambahan Hidroksipropil
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Indra, Indra, Ahmad Fauzi, and Ratih Aryani. "Karakterisasi dan Uji Disolusi Aspirin Hasil Rekristalisasi Penguap Pelarut." Jurnal Sains Farmasi & Klinis 6, no. 2 (2019): 164. http://dx.doi.org/10.25077/jsfk.6.2.164-170.2019.

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Aspirin merupakan obat analgetik dan antipiretik yang termasuk dalam kelompok Biopharmaceutical Classification System (BCS) kelas II dengan kelarutan rendah dan absorpsi tinggi. Pada penelitian ini telah dilakukan modifikasi kristal aspirin untuk meningkatkan laju disolusi dengan menggunakan metode rekristaliasi penguapan 3 jenis pelarut yaitu methanol (AMP), tetrahidrofuran (ATP) dan kloroform (AKP). Karakteristik sifat fisikokimia hasil rekristalisasi aspirin dilakukan menggunakan mikroskop polarisasi, X-Ray difraktometer serbuk, Spektrofotometer IR, differential scanning calorimeter (DSC) d
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Dissertations / Theses on the topic "Disoluce"

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Voda, Zbyšek. "Vestavěná řídicí jednotka pro ovládání laboratorního zařízení." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2020. http://www.nusl.cz/ntk/nusl-417222.

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Aim of this thesis is modular design of control system for Golem device, which is used for drug research. Several modules with specified controlled area were designed. They communicate using CAN bus and are controlled by Raspberry Pi computer. The thesis includes PCB design and control firmware for modules, backend application for Raspberry Pi, which provides application interface, and simple protocol used for communication between modules. Designed system was tested in simulated environment.
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Truhlář, Jan. "Softwarový nástroj pro vizuální specifikaci řízení průběhu laboratorních experimentů." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2020. http://www.nusl.cz/ntk/nusl-433536.

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Aim of this work is to design and create a software tool, which will allow visual specification of laboratory experiments flow on device called GOLEM. This device was created by research group from Department of Chemical Drugs, University of Veterinary and Pharmaceutical Sciences Brno. This software was based on modern web technologies, tools for their design and implementation. The software created in this work offers ergonomic and the highly modular user interface which can be easily extended in case of upgrade. Main benefit of this work is providing research group with a new software tool w
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Hofmanová, Markéta. "Disoluce z mikrovlákenných nosičů 1." Master's thesis, 2014. http://www.nusl.cz/ntk/nusl-337352.

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Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of: Pharmaceutical technology Consultant: Doc. PharmDr. Zdeňka Šklubalová, Ph.D. Student: Markéta Hofmanová Title of Thesis: Dissolution from microfibre carriers 1. The aim of Diploma Thesis was to study of the effect of conditions of dissolution on the release of a model drug from microfibre carriers. A modified hyaluronan microfiber covered with the drug, dexamethasoni natrii phosphas, was used as a carrier. The drug was directly released from the microfibres and/or from the microfibre enclosed in a dialysis membr
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Dušková, Lucie. "Hodnocení disoluce tablet obsahujících theofylin a směsi dvou typů hydrogenfosforečnanu vápenatého a laktosy." Master's thesis, 2015. http://www.nusl.cz/ntk/nusl-333477.

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1 Abstract Charles University in Prague, Faculty of Pharmacy in Hradci Králové Department of: Pharmaceutical technology Consultant: Doc. PharmDr. Zdeňka Šklubalová, Ph.D. Student: Lucie Dušková Title of Thesis: Dissolution testing of tablets containing theophylline and mix- tures of two types of calcium hydrogen phosphates and lactose The aim of this diploma thesis was to study effect of the composition of pow- ders on the tablets dissolution. The mixtures that had been used to prepare the tablets that were composed of three types of fillers - lactose, calcium hyd- rogen phosphate anhydrous an
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Vávrová, Kateřina. "Hodnocení disoluce tablet obsahujících theofylin a směsi dvou typů hydrogenfosforečnanu vápenatého a mikrokrystalické celulosy." Master's thesis, 2017. http://www.nusl.cz/ntk/nusl-367733.

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Charles University in Prague, Faculty of Pharmacy in Hradci Králové Department of Pharmaceutical technology Consultant: PharmDr. Pavel Ondrejček, Ph.D. Student: Kateřina Vávrová Title of Thesis: Dissolution testing of tablets containing theophylline and mixtures of two types of calcium hydrogen phosphates and microcrystalline cellulose The aim of this thesis was the dissolution testing of tablets containing theophylline, the mixture of two dicalcium phosphate types and microcrystalline cellulose. The influence of tablet composition on the dissolution profiles was evaluated. The tablets were pr
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Ouzký, Miroslav. "Studium vlivu pomocných látek na disoluci léčiva z tablet." Master's thesis, 2020. http://www.nusl.cz/ntk/nusl-411618.

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Charles University, Faculty of Pharmacy in Hradec Králové Department of: Pharmaceutical Technology Supervisor: Consultants: Assoc. Prof. PharmDr. Zdeňka Šklubalová, Ph.D. Mgr. Jana Brokešová, Mgr. Daniel Pěček Student: Miroslav Ouzký Title of Thesis: Study of excipientsʼ influence on the drug dissolution from tablets The aim of this work was to study the influence of excipients on the dissolution of the high-dose active substance from tablets. The tablets were compressed from the granules prepared by wet-granulation method. 11 batches of tablets which contained two different fillers: either la
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Hafezi, Ramin. "Formulace a charakterizace PLGA nanočástic s oximy." Master's thesis, 2021. http://www.nusl.cz/ntk/nusl-445737.

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Thesis title: Formulation and characterization of oxime loaded PLGA nanoparticles Author: Ramin Hafezi Supervisor: PharmDr. Eva Šnejdrová, Ph.D. Advisor: PharmDr. Juraj Martiška, Ph.D. Department: Department of Pharmaceutical Technology The diploma thesis was focused on PLGA nanoparticles (NPs) which could be loaded with oximes, prepared by a double emulsion technique, and characterised by size, polydispersity and zeta potential. The theoretical part deals with the most common methods of the NPs preparation, the polymers and stabilizers employed, and drug delivery to brain. In the experimental
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Books on the topic "Disoluce"

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Asuntos de un hidalgo disoluto. T-M Editores, 1994.

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Kovačević, Ivan. Antropologija između scijentizma i disolucije. Srpski Genealoški Centar, 2010.

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Cornea, Paul, writer of added commentary, ed. Identitate și disoluție: Introducere în opera lui Mircea Ciobanu. Editura Muzeul Literaturii Române, 2010.

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Bookchin, Murray. La ecologi a de la libertad: El surgimiento y la disolucio n de la jerarqui a. Nossa y Jara Editores, 1999.

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Prophet, Elizabeth Clare. Disuelve tus problemas/ Disolve Your Problems. Porcia Pub Corp, 2005.

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Asuntos de un hidalgo disoluto. - 1.Ed. TM, 1994.

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Azizah, Nasution, and Universitas Sumatera Utara. Proyek Operasi dan Perawatan Fasilitas., eds. Studi komparatip disolusi dan biovailabilitas beberapa sediaan generik dan paten tablet parasetamol yang beredar di pasaran Kotamadya Medan: Laporan penelitian. Departemen Pendidikan dan Kebudayaan R.I., Proyek Operasi dan Perawatan Fasilitas, Universitas Sumatera Utara, 1994.

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Conference papers on the topic "Disoluce"

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Hasanah, Uswatun, Mirhansyah Ardana, and Rolan Rusli. "PENGARUH pH MEDIUM TERHADAP DISOLUSI IBUPROFEN DENGAN METODE DISPERSI PADAT." In Mulawarman Pharmaceuticals Conferences. Fakultas Farmasi, Universitas Mulawarman, Samarinda, 2015. http://dx.doi.org/10.25026/mpc.v1i1.15.

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Kushida, Takeo. "High Speed, Powerful and Simple Solenoid Actuator “DISOLE” and its Dynamic Analysis Results." In SAE International Congress and Exposition. SAE International, 1985. http://dx.doi.org/10.4271/850373.

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Pašić, Jasna. "NA PUTU OD AVNOJ-A DO ZAVNOBIH-a, HISTORIJSKA MJESTA I DINAMIKA SJEĆANJA." In Međunarodna naučna konferencija-75. GODIŠNJICA PRVOG ZASJEDANJA ZAVNOBIH-a: POVIJESNA UTEMELJENOST OBNOVLJENE DRŽAVNOSTI BOSNE I HERCEGOVINE U 20. I 21. STOLJEĆU. Academy of Sciences and Arts of Bosnia and Herzegovina, 2019. http://dx.doi.org/10.5644/pi2019.179.13.

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Autorica u radu ukazuje na značaj Prvog zasjedanja AVNOJ-a i njegov utjecaj na osnivanje ZAVNOBiH-a, u kontekstu izgradnje državne vlasti i obnove državnosti Bosne i Hercegovine. Promatranje uloge historijskog mjesta, kao simboliziranog prostora u obilježavanju značajnih historijskih događaja, omogućava sagledavanje promjena vrijednosnih okvira koji su oblikovali dominantne javne percepcije. Odnos prema razvoju državnosti Bosne i Hercegovine, praćen na primjerima Bihaća, Mrkonjić-Grada i Jajca, prikazuje utjecaj društveno-političkih događanja na dinamiku sjećanja i valorizaciju tekovina antifa
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Šehić, Zijad. "POVIJESNA UTEMELJENOST DRŽAVNOSTI BOSNE I HERCEGOVINE." In Međunarodna naučna konferencija-75. GODIŠNJICA PRVOG ZASJEDANJA ZAVNOBIH-a: POVIJESNA UTEMELJENOST OBNOVLJENE DRŽAVNOSTI BOSNE I HERCEGOVINE U 20. I 21. STOLJEĆU. Academy of Sciences and Arts of Bosnia and Herzegovina, 2019. http://dx.doi.org/10.5644/pi2019.179.02.

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U članku autor ukazuje na historijske prijelomnice, ključne za izgradnju identiteta bosanskohercegovačke posebnosti i paradigme jedinstva u različitosti. Promatra dugu genezu bh. državnosti, od vremena Kulina bana (1180– 1204) u kojem je afirmirana srednjovjekovna bosanska država, koja je svoju kulminaciju doživjela tokom vladavine Tvrtka I Kotromanića (1353–1391) kada je postala kraljevinom (1377). Period osmanske, austrougarske i uprave Kraljevine SHS / Kraljevine Jugoslavije autor promatra u kontekstu međunarodne diplomatije, javnog i tajnog aspekta nacionalnih težnji prema Bosni i Hercegov
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Kožar, Azem. "Historijski apsekti izučavanja rata u Bosni i Hercegovini (1992–1995)." In Međunaordna naučno-kulturološka konferencija “Istoriografija o BiH (2001–2017 )”. Academy of Sciences and Arts of Bosnia and Herzegovina, 2020. http://dx.doi.org/10.5644/pi2020.186.17.

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Proces disolucije Socijalističke Federativne Republike Jugoslavije (SFRJ) na federalne jedinice – socijalističke republike, odvijao se kroz ratne sukobe u posljednjoj deceniji dvadesetog stoljeća. Glavni generatori toga procesa bili su agresivni nacionalizmi koji su ratom nastojali ostvariti svoje velikodržavne projekte, između ostaloga, razgradnjom i podjelom Republike Bosne i Hercegovine. Ipak, uz pomoć međunarodne zajednice, sve bivše socijalističke republike postale su samostalne i nezavisne države – a među njima i Republika Bosna i Hercegovina. Najteža ratna stradanja ljudi i razaranja ma
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Pejanović, Mirko. "KONTINUITET RAZVOJA DRŽAVNOSTI BOSNE I HERCEGOVINE OD PRVOG ZASJEDANJA ZAVNOBIH-a 1943. GODINE DO REFERENDUMA GRAĐANA O SUVERENOSTI I NEZAVISNOSTI 1992. GODINE." In Međunarodna naučna konferencija-75. GODIŠNJICA PRVOG ZASJEDANJA ZAVNOBIH-a: POVIJESNA UTEMELJENOST OBNOVLJENE DRŽAVNOSTI BOSNE I HERCEGOVINE U 20. I 21. STOLJEĆU. Academy of Sciences and Arts of Bosnia and Herzegovina, 2019. http://dx.doi.org/10.5644/pi2019.179.01.

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Obnova i razvoj državnosti Bosne i Hercegovine u drugoj polovini dvadesetog stoljeća odvija se u kontinuitetu u periodu od odluka ZAVNOBiH-a 1943. do referenduma građana o suverenom i nezavisnom državno-pravnom statusu Bosne i Hercegovine 1992. godine. U vremenu od pet decenija, Bosna i Hercegovina je prošla tri društveno-istorijska perioda. Prvo, to je period razvoja Bosne i Hercegovine u doba državnog centralizma u jugoslovenskoj federaciji od 1945. do 1963. godine. U tom periodu, prema istraživanjima akademika Dušana Bilandžića, Bosna i Hercegovina nema sve odlike samostalnosti u privrednom
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