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Journal articles on the topic 'Disorders of consciousness'

Author: Grafiati

Published: 4 June 2021

Last updated: 15 June 2025

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1

NAGATAKI, SHIGENOBU. "Consciousness disorders and dementia : progress in diagnosis and treatment. 1. Consciousness disorders. 5. Consciousness disorders in the elderly. 4. Endocrinological disorders and consciousness disorders." Nihon Naika Gakkai Zasshi 79, no. 4 (1990): 463–67. http://dx.doi.org/10.2169/naika.79.463.

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2

Schiff, Nicholas D., and Joseph J. Fins. "Disorders of Consciousness." Mayo Clinic Proceedings 82, no. 2 (2007): 250–51. http://dx.doi.org/10.4065/82.2.250-a.

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3

ASHWAL, STEPHEN. "Disorders of consciousness." Developmental Medicine & Child Neurology 55, no. 1 (2012): 5–6. http://dx.doi.org/10.1111/dmcn.12031.

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4

Owen, Adrian M. "Disorders of Consciousness." Annals of the New York Academy of Sciences 1124, no. 1 (2008): 225–38. http://dx.doi.org/10.1196/annals.1440.013.

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5

Bernat, James L. "Chronic Consciousness Disorders." Annual Review of Medicine 60, no. 1 (2009): 381–92. http://dx.doi.org/10.1146/annurev.med.60.060107.091250.

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6

Schiff, Nicholas D., and Joseph J. Fins. "Disorders of Consciousness." Mayo Clinic Proceedings 82, no. 2 (2007): 250–51. http://dx.doi.org/10.1016/s0025-6196(11)61007-0.

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7

Eapen, Blessen C., Jason Georgekutty, Bruno Subbarao, Sheital Bavishi, and David X. Cifu. "Disorders of Consciousness." Physical Medicine and Rehabilitation Clinics of North America 28, no. 2 (2017): 245–58. http://dx.doi.org/10.1016/j.pmr.2016.12.003.

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8

KOTHARI, SUNIL, and BEI ZHANG. "Disorders of Consciousness." Physical Medicine and Rehabilitation Clinics of North America 35, no. 1 (2024): i. http://dx.doi.org/10.1016/s1047-9651(23)00112-2.

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9

SAITO, TOSHIKAZU. "Consciousness disorders and dementia : progress in diagnosis and treatment. 1. Consciousness disorders. 5. Consciousness disorders in the elderly. 3. Electrolyte imbalances and consciousness disorders." Nihon Naika Gakkai Zasshi 79, no. 4 (1990): 457–62. http://dx.doi.org/10.2169/naika.79.457.

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10

Sigawi, Tal, Omer Hamtzany, Josef Daniel Shakargy, and Yaron Ilan. "The Constrained Disorder Principle May Account for Consciousness." Brain Sciences 14, no. 3 (2024): 209. http://dx.doi.org/10.3390/brainsci14030209.

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There is still controversy surrounding the definition and mechanisms of consciousness. The constrained disorder principle (CDP) defines complex systems by their dynamic borders, limiting their inherent disorder. In line with the CDP, the brain exhibits a disorder bounded by dynamic borders essential for proper function, efficient energy use, and life support under continuous perturbations. The brain’s inherent variability contributes to its adaptability and flexibility. Neuronal signal variability challenges the association of brain structures with consciousness and methods for assessing consciousness. The present paper discusses some theories about consciousness, emphasizing their failure to explain the brain’s variability. This paper describes how the CDP accounts for consciousness’s variability, complexity, entropy, and uncertainty. Using newly developed second-generation artificial intelligence systems, we describe how CDP-based platforms may improve disorders of consciousness (DoC) by accounting for consciousness variability, complexity, entropy, and uncertainty. This platform could be used to improve response to current interventions and develop new therapeutic regimens for patients with DoC in future studies.

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11

TERASHI, AKIRO. "Consciousness disorder and dementia : Progress in diagnosis and treatment. 1. Consciousness disorder. 5. Consciousness disorder in elderly persons. 1. Consciousness disorder in cerebrovascular disorders." Nihon Naika Gakkai Zasshi 79, no. 4 (1990): 446–51. http://dx.doi.org/10.2169/naika.79.446.

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12

Mulkey, Malissa. "Understanding Disorders of Consciousness: Opportunities for Critical Care Nurses." Critical Care Nurse 41, no. 6 (2021): 36–44. http://dx.doi.org/10.4037/ccn2021344.

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Background Disorders of consciousness are powerful predictors of outcomes including mortality among critically ill patients. Encephalopathy, delirium, and coma are disorders of consciousness frequently encountered by critical care nurses but often classified incorrectly. Objective To provide a greater understanding of disorders of consciousness and to provide standardized assessments and nursing interventions for these disorders. Methods A literature search was conducted by using the terms consciousness, mental status, awareness, arousal, wakefulness, assessment, disorders of consciousness, delirium, encephalopathy, coma, vegetative state, and minimal consciousness. Articles were published in the past 10 years in CINAHL and PubMed. Articles were excluded if they were not in English or directly related to caring for patients with a disorder of consciousness. The remaining 142 articles were evaluated for inclusion; 81 articles received full review. Results A disorder of consciousness signifies that the threshold for compensation has been surpassed with potentially irreversible damage. Altered thalamocortical interactions and reduced cortical activity impair communication networks across the various parts of the brain, causing a disturbance in consciousness. Discussion The cue-response theory is a model that describes the process and impact of nursing care on recovery from acute brain injury. Appropriate standardized assessments and interventions must be used to manage altered levels of consciousness in critically ill patients. Conclusions Paying close attention to neurological changes and monitoring them with standardized assessments are critical to implementing early measures to prevent complications.

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13

Kim, Daeyoung. "Prolonged Disorders of Consciousness." Journal of the Korean Neurological Association 38, no. 1 (2020): 9–15. http://dx.doi.org/10.17340/jkna.2020.1.2.

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Prolonged disorders of consciousness comprise a spectrum of impaired consciousness where arousal is preserved with impaired awareness, which last more than 4 weeks. Vegetative state is a prototype of the prolonged disorders of consciousness. A patient in the vegetative state has no signs of awareness. The minimally conscious state is characterized by inconsistent but reproducible signs of awareness and is regarded as a transitional state of recovery of consciousness. Differentiating patients in minimally conscious state from those in vegetative state is still challenging. Utilizing standardized neurobehavioral assessment tools could improve diagnostic accuracy. Recent advances in neuroimaging and electrophysiologic tools may aid the diagnosis and prognostication. Treatment for recovery of consciousness is still limited. More research on the diagnosis and treatment of prolonged disorders of consciousness is needed not only for improved care of patients with prolonged disorders of consciousness but also a greater understanding of human consciousness.

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14

Pajankar, Netri. "Diagnosing Disorders of Consciousness." Sciential - McMaster Undergraduate Science Journal, no. 2 (March 29, 2019): 34–36. http://dx.doi.org/10.15173/sciential.v1i2.2099.

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The definition of consciousness has long been debated in a scientific and philosophical context due to its ambiguous nature. Recent developments in the concept of consciousness have contributed to a better understanding of associated Disorders of Consciousness (DOC). However, there has not been an equivalent rise in the accuracy of diagnostic measures for DOC. About half of the patients with DOC are incorrectly diagnosed due to significant reliance on subjective and inaccurate behavioural scales. Consequently, the misrepresentation of a patient’s present residual consciousness severely affects the treatment and rehabilitation measures that they receive. These inaccurate diagnoses ultimately influence the patient’s chance of survival. Thus, it is necessary to critique the current methods of evaluating consciousness. Neurophysiological scales are explored as a possible alternative method of evaluating consciousness, which is characterized by high sensitivity and objectivity. An understanding of the advantages and disadvantages of different consciousness-evaluating techniques can aid in the advocacy of their widespread use for DOC patients.

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15

Xie, Qiuyou, Xiaoxiao Ni, Ronghao Yu, Yuanqing Li, and Ruiwang Huang. "Chronic disorders of consciousness." Experimental and Therapeutic Medicine 14, no. 2 (2017): 1277–83. http://dx.doi.org/10.3892/etm.2017.4639.

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16

Bernat, James L. "Chronic disorders of consciousness." Lancet 367, no. 9517 (2006): 1181–92. http://dx.doi.org/10.1016/s0140-6736(06)68508-5.

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17

Bayne, Tim, and Jakob Hohwy. "Global disorders of consciousness." Wiley Interdisciplinary Reviews: Cognitive Science 5, no. 2 (2013): 129–38. http://dx.doi.org/10.1002/wcs.1270.

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18

KOWA, HISAYUKI. "Consciousness disorders and dementia : progress in diagnosis and treatment. 1. Consciousness disorders. 3. Emergency treatment for patients with consciousness disorders." Nihon Naika Gakkai Zasshi 79, no. 4 (1990): 435–39. http://dx.doi.org/10.2169/naika.79.435.

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19

Dostović, Zikrija, Dževdet Smajlović, Ernestina Dostović, and Omer Ć. Ibrahimagić. "Stroke and Disorders of Consciousness." Cardiovascular Psychiatry and Neurology 2012 (September 3, 2012): 1–4. http://dx.doi.org/10.1155/2012/429108.

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Objectives. To determine the severity of stroke and mortality in relation to the type of disturbance of consciousness and outcome of patients with disorders of consciousness. Patients and Methods. We retrospectively analyzed 201 patients. Assessment of disorders of consciousness is performed by Glasgow Coma Scale (Teasdale and Jennet, 1974) and the Diagnostic and Statistical Manual of Mental Disorders (Anonymous, 2000). The severity of stroke was determined by National Institutes of Health Stroke Scale (Lyden et al., 2011). Results. Fifty-four patients had disorders of consciousness (26.9%). Patients with disorders of consciousness on admission (P<0.001) and discharge (P=0.003) had a more severe stroke than patients without disturbances of consciousness. Mortality was significantly higher in patients with disorders of consciousness (P=0.0001), and there was no difference in mortality in relation to the type of disturbance of consciousness. There is no statistically significant effect of specific predictors of survival in patients with disorders of consciousness. Conclusion. Patients with disorders of consciousness have a more severe stroke and higher mortality. There is no difference in mortality and severity of stroke between patients with quantitative and qualitative disorders of consciousness. There is no statistically significant effect of specific predictors of survival in patients with disorders of consciousness.

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20

Gao, Jian, Min Wu, Yuehao Wu, and Ping Liu. "Emotional consciousness preserved in patients with disorders of consciousness?" Neurological Sciences 40, no. 7 (2019): 1409–18. http://dx.doi.org/10.1007/s10072-019-03848-w.

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21

Wijdicks, Eelco F. M. "Disorders of Consciousness–Reply–I." Mayo Clinic Proceedings 82, no. 2 (2007): 251. http://dx.doi.org/10.4065/82.2.251.

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22

Katz, Douglas, John Whyte, and Joseph Giacino. "Neurorehabilitation in Disorders of Consciousness." Seminars in Neurology 33, no. 02 (2013): 142–56. http://dx.doi.org/10.1055/s-0033-1348960.

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23

Cavanna, Andrea Eugenio. "Epilepsy and Disorders of Consciousness." Behavioural Neurology 24, no. 1 (2011): 1. http://dx.doi.org/10.1155/2011/646483.

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24

Wijdicks, Eelco F. M. "Disorders of Consciousness–Reply–I." Mayo Clinic Proceedings 82, no. 2 (2007): 251. http://dx.doi.org/10.1016/s0025-6196(11)61008-2.

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25

Cologan, Victor, Manvel Schabus, Didier Ledoux, Gustave Moonen, Pierre Maquet, and Steven Laureys. "Sleep in disorders of consciousness." Sleep Medicine Reviews 14, no. 2 (2010): 97–105. http://dx.doi.org/10.1016/j.smrv.2009.04.003.

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26

Snider, Samuel B., and Brian L. Edlow. "MRI in disorders of consciousness." Current Opinion in Neurology 33, no. 6 (2020): 676–83. http://dx.doi.org/10.1097/wco.0000000000000873.

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27

Zhao, Jizong. "Disorders of Consciousness in China." Neuroscience Bulletin 34, no. 4 (2018): 605–14. http://dx.doi.org/10.1007/s12264-018-0263-1.

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28

ARAKI, GORO. "Consciousness disorders and dementia : progress in diagnosis and treatment. 1. Consciousness disorders. 6. Syncope." Nihon Naika Gakkai Zasshi 79, no. 4 (1990): 480–85. http://dx.doi.org/10.2169/naika.79.480.

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29

Cacciatore, Martina, Francesca G. Magnani, Matilde Leonardi, Davide Rossi Sebastiano, and Davide Sattin. "Sleep Treatments in Disorders of Consciousness: A Systematic Review." Diagnostics 12, no. 1 (2021): 88. http://dx.doi.org/10.3390/diagnostics12010088.

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Sleep disorders are among the main comorbidities in patients with a Disorder of Consciousness (DOC). Given the key role of sleep in neural and cognitive functioning, detecting and treating sleep disorders in DOCs might be an effective therapeutic strategy to boost consciousness recovery and levels of awareness. To date, no systematic reviews have been conducted that explore the effect of sleep treatments in DOCs; thus, we systematically reviewed the existing studies on both pharmacological and non-pharmacological treatments for sleep disorders in DOCs. Among 2267 assessed articles, only 7 were included in the systematic review. The studies focused on two sleep disorder categories (sleep-related breathing disorders and circadian rhythm dysregulation) treated with both pharmacological (Modafinil and Intrathecal Baclofen) and non-pharmacological (positive airway pressure, bright light stimulation, and central thalamic deep brain stimulation) interventions. Although the limited number of studies and their heterogeneity do not allow generalized conclusions, all the studies highlighted the effectiveness of treatments on both sleep disorders and levels of awareness. For this reason, clinical and diagnostic evaluations able to detect sleep disorders in DOC patients should be adopted in the clinical routine for the purpose of intervening promptly with the most appropriate treatment.

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30

Fischer, David, and Robert D. Truog. "The Problems With Fixating on Consciousness in Disorders of Consciousness." AJOB Neuroscience 8, no. 3 (2017): 135–40. http://dx.doi.org/10.1080/21507740.2017.1366577.

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31

Peterson, Andrew, and Tim Bayne. "A Taxonomy for Disorders of Consciousness That Takes Consciousness Seriously." AJOB Neuroscience 8, no. 3 (2017): 153–55. http://dx.doi.org/10.1080/21507740.2017.1371807.

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32

Nora, Gerald J. "Disorders of Consciousness: Terminology and Prognosis." Ethics & Medics 45, no. 12 (2020): 1–2. http://dx.doi.org/10.5840/em2020451221.

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Patients with disorders of consciousness have been at the heart of some of the most heated debates on so-called right-to-die cases such as the Terri Schiavo case. People with DOCs occupy a spectrum of disorders from coma to the minimally conscious state. Recent advances in neuroscience have led to insights on the mechanism of these disorders as well as to the revelation that some patients might have a greater degree of awareness than previously believed. These scientific developments have paralleled long-term clinical follow-ups, which have also shown more positive outcomes than expected.

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33

Monti, Martin. "Ultrasonic stimulation in disorders of consciousness." Brain Stimulation 14, no. 6 (2021): 1746–47. http://dx.doi.org/10.1016/j.brs.2021.10.532.

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34

Chatelle, Camille, Aurore Thibaut, John Whyte, Marie Danièle De Val, Steven Laureys, and Caroline Schnakers. "Pain issues in disorders of consciousness." Brain Injury 28, no. 9 (2014): 1202–8. http://dx.doi.org/10.3109/02699052.2014.920518.

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35

Geocadin, Romergryko, and Hans Püttgen. "Acute Coma and Disorders of Consciousness." Seminars in Neurology 33, no. 02 (2013): 081–82. http://dx.doi.org/10.1055/s-0033-1348957.

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36

Chatelle, Camille, Brian Edlow, and Yelena Bodien. "Functional Networks in Disorders of Consciousness." Seminars in Neurology 37, no. 05 (2017): 485–502. http://dx.doi.org/10.1055/s-0037-1607310.

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AbstractSevere brain injury may cause disruption of neural networks that sustain arousal and awareness, the two essential components of consciousness. Despite the potentially devastating immediate and long-term consequences, disorders of consciousness (DoC) are poorly understood in terms of their underlying neurobiology, the relationship between pathophysiology and recovery, and the predictors of treatment efficacy. Recent advances in neuroimaging techniques have enabled the study of network connectivity, providing great potential to improve the clinical care of patients with DoC. Initial discoveries in this field were made using positron emission tomography (PET). More recently, functional magnetic resonance (fMRI) techniques have added to our understanding of functional network dynamics in this population. Both methods have shown that whether at rest or performing a goal-oriented task, functional networks essential for processing intrinsic thoughts and extrinsic stimuli are disrupted in patients with DoC compared with healthy subjects. Atypical connectivity has been well established in the default mode network as well as in other cortical and subcortical networks that may be required for consciousness. Moreover, the degree of altered connectivity may be related to the severity of impaired consciousness, and recovery of consciousness has been shown to be associated with restoration of connectivity. In this review, we discuss PET and fMRI studies of functional and effective connectivity in patients with DoC and suggest how this field can move toward clinical application of functional network mapping in the future.

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37

Coleman, Martin R., and Adrian M. Owen. "Functional Neuroimaging of Disorders of Consciousness." International Anesthesiology Clinics 46, no. 3 (2008): 147–57. http://dx.doi.org/10.1097/aia.0b013e318181adcc.

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38

Boly, Mélanie, Marcello Massimini, Marta Isabel Garrido, et al. "Brain Connectivity in Disorders of Consciousness." Brain Connectivity 2, no. 1 (2012): 1–10. http://dx.doi.org/10.1089/brain.2011.0049.

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39

Samson, Kurt. "In the Clinic-Disorders of Consciousness." Neurology Today 18, no. 16 (2018): 1. http://dx.doi.org/10.1097/01.nt.0000544622.26205.46.

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40

Aschroft, Richard. "Brain Death and Disorders of Consciousness." Lancet Neurology 3, no. 11 (2004): 692. http://dx.doi.org/10.1016/s1474-4422(04)00912-3.

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41

Di Perri, Carol, Johan Stender, Steven Laureys, and Olivia Gosseries. "Functional neuroanatomy of disorders of consciousness." Epilepsy & Behavior 30 (January 2014): 28–32. http://dx.doi.org/10.1016/j.yebeh.2013.09.014.

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42

Seregni, F., M. Fecchio, M. Rosanova, et al. "Cortical bistability and disorders of consciousness." Neurophysiologie Clinique/Clinical Neurophysiology 43, no. 5-6 (2013): 322. http://dx.doi.org/10.1016/j.neucli.2013.10.031.

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43

Cruse, Damian, and G. Bryan Young. "The complexity of disorders of consciousness." Clinical Neurophysiology 127, no. 2 (2016): 1001–2. http://dx.doi.org/10.1016/j.clinph.2015.08.018.

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44

Fins, Joseph J., Megan S. Wright, and Samuel R. Bagenstos. "Disorders of Consciousness and Disability Law." Mayo Clinic Proceedings 95, no. 8 (2020): 1732–39. http://dx.doi.org/10.1016/j.mayocp.2020.02.008.

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45

Schiff, Nicholas D., and Joseph J. Fins. "Brain death and disorders of consciousness." Current Biology 26, no. 13 (2016): R572—R576. http://dx.doi.org/10.1016/j.cub.2016.02.027.

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46

De Paepe, Peter, Sabine Lemoyne, and Walter Buylaert. "Disorders of Consciousness Induced by Intoxication." Neurologic Clinics 30, no. 1 (2012): 359–84. http://dx.doi.org/10.1016/j.ncl.2011.10.003.

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47

Guldenmund, P., J. Stender, L. Heine, and S. Laureys. "Mindsight: Diagnostics in Disorders of Consciousness." Critical Care Research and Practice 2012 (2012): 1–13. http://dx.doi.org/10.1155/2012/624724.

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Diagnosis of patients with disorders of consciousness (comprising coma, vegetative state/unresponsive wakefulness syndrome, and minimally conscious state) has long been dependent on unstandardized behavioral tests. The arrival of standardized behavioral tools, and especially the Coma Recovery Scale revised, uncovered a high rate of misdiagnosis. Ancillary techniques, such as brain imaging and electrophysiological examinations, are ever more often being deployed to aid in the search for remaining consciousness. They are used to look for brain activity patterns similar to those found in healthy controls. The development of portable and cheaper devices will make these techniques more widely available.

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48

Aoyagi, Yoichiro. "Disorders of Consciousness and Rehabilitation Medicine." Japanese Journal of Rehabilitation Medicine 57, no. 1 (2020): 4–10. http://dx.doi.org/10.2490/jjrmc.57.4.

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49

Specker Sullivan, Laura. "Pure Experience and Disorders of Consciousness." AJOB Neuroscience 9, no. 2 (2018): 107–14. http://dx.doi.org/10.1080/21507740.2018.1459931.

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50

McKinney, James S., and Joseph T. Giacino. "Diagnostic Accuracy in Disorders of Consciousness." Neurologist 14, no. 5 (2008): 340. http://dx.doi.org/10.1097/nrl.0b013e31816722d4.

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