Relevant bibliographies by topics / Dissertations – Pharmacology

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  1. Journal articles
  2. Dissertations / Theses

Academic literature on the topic 'Dissertations – Pharmacology'

Author: Grafiati
Published: 4 June 2021
Last updated: 6 February 2022

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Journal articles on the topic "Dissertations – Pharmacology"

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Yang, Min, Xue Li, Lei Zhang, et al. "Ethnopharmacology, Phytochemistry, and Pharmacology of the Genus Glehnia: A Systematic Review." Evidence-Based Complementary and Alternative Medicine 2019 (December 14, 2019): 1–33. http://dx.doi.org/10.1155/2019/1253493.

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Glehnia littoralis Fr. Schmidt ex Miq, the sole species in the genus Glehnia (Apiaceae), has long been used in traditional Chinese medicine to treat fatigue, weakness, stomach-yin deficiency, lung heat, cough, dry throat, and thirst. Recently, G. littoralis has also been incorporated into a wide range of Chinese vegetarian cuisines. Based on the comprehensive information, advances in botany, known uses, phytochemistry, pharmacology, and toxicity of G. littoralis, we aim to highlight research gaps and challenges in studying G. littoralis as well as to explore its potential use in plant biotechn
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Maroyi, Alfred. "LANNEA ACIDA: A REVIEW OF ITS MEDICINAL USES AND PHYTOCHEMISTRY AND PHARMACOLOGICAL PROPERTIES." Asian Journal of Pharmaceutical and Clinical Research 11, no. 11 (2018): 69. http://dx.doi.org/10.22159/ajpcr.2018.v11i11.28813.

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Lannea acida is widely used as herbal medicine in West Africa. The present study critically reviewed the medicinal uses and phytochemistry and pharmacological properties of L. acida. The keywords including L. acida, its synonyms, English common names, medicinal uses, and phytochemistry and pharmacological properties of the species were searched using electronic databases such as ISI web of knowledge, ProQuest, ScienceDirect, OATD, Scopus, OpenThesis, PubMed, and Google Scholar. The search for pre-electronic literature such as conference papers, scientific articles, books, book chapters, disser
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Yang, Liu, Ajiao Hou, Song Wang, et al. "A Review of the Botany, Traditional Use, Phytochemistry, Analytical Methods, Pharmacological Effects, and Toxicity of Angelicae Pubescentis Radix." Evidence-Based Complementary and Alternative Medicine 2020 (August 3, 2020): 1–28. http://dx.doi.org/10.1155/2020/7460781.

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Angelicae Pubescentis Radix (AP), as a traditional Chinese medicine (TCM), has been used for thousands of years in China. In this paper, the botany, traditional use, phytochemistry, analytical methods, quality control, pharmacological effects, and toxicity of AP were reviewed. It can provide a reference for the further research and lay a foundation for the rational clinical application of AP. The relevant information on AP was collected from scientific databases (such as Baidu Scholar, CNKI, Google Scholar, PubMed, Science Direct, Web of Science, and SciFinder Scholar), Chinese herbal classics
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Maroyi, Alfred. "A REVIEW OF THE ETHNOMEDICINAL USES, PHYTOCHEMISTRY AND PHARMACOLOGICAL PROPERTIES OF EKEBERGIA CAPENSIS SPARRM." Asian Journal of Pharmaceutical and Clinical Research 11, no. 10 (2018): 59. http://dx.doi.org/10.22159/ajpcr.2018.v11i10.28816.

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Ekebergia capensis is an integral part of indigenous pharmacopeia in tropical Africa. The present study critically reviewed the ethnomedicinal uses, phytochemistry, and pharmacological properties of E. capensis. The keywords including E. capensis, its synonyms, English common names, ethnomedicinal uses, and phytochemistry and pharmacological properties of the species were searched using electronic databases such as ISI web of knowledge, ProQuest, science direct, OATD, Scopus, Open-thesis, PubMed, and Google Scholar. Pre-electronic literature of conference papers, scientific articles, books, bo
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Puri, Abhijeet V. "DURANTA REPENS LINN. (VERBENACEAE): A COMPREHENSIVE REVIEW OF PHARMACOGNOSTIC, ETHNOMEDICINAL, PHARMACOLOGICAL, AND PHYTOCHEMICAL ASPECTS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 11 (2018): 91. http://dx.doi.org/10.22159/ajpcr.2018.v11i11.28509.

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Objective: This review is intended to investigate the published report regarding phytochemical, ethnomedicinal, and pharmacological activities and put forth the therapeutic potential of Duranta repens Linn. (D. repens). It belongs to the family Verbenaceae, one of the therapeutically important plants, broadly distributed all throughout the world. It is commonly referred as golden dewdrop, angel whisper, pigeon berry, or skyflower.Methods: I utilized logical writing and scientific literature regarding D. repens by referring search engine such as Springerlink, ScienceDirect, SciFinder, PubMed, S
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Rodrigues, Claire R., Amanda R. Harrington, Nicole Murdock, et al. "Effect of Pharmacy-Supported Transition-of-Care Interventions on 30-Day Readmissions: A Systematic Review and Meta-analysis." Annals of Pharmacotherapy 51, no. 10 (2017): 866–89. http://dx.doi.org/10.1177/1060028017712725.

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Objective: To describe pharmacy-supported transition-of-care (TOC) interventions and determine their effect on 30-day all-cause readmissions. Data Sources: MEDLINE/PubMed, EMBASE, International Pharmaceutical Abstracts, ABI Inform Complete, PsychINFO, Web of Science, Academic Search Complete, CINHAL, Cochrane library, OIASTER, ProQuest Dissertations & Theses, ClinicalTrials.gov , and relevant websites were searched from January 1, 1995, to December 31, 2015. Study Selection and Data Extraction: PICOS+E criteria were utilized. Eligible studies reported pharmacy-supported TOC interventions c
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Slimings, Claudia, and Thomas V. Riley. "Antibiotics and healthcare facility-associated Clostridioides difficile infection: systematic review and meta-analysis 2020 update." Journal of Antimicrobial Chemotherapy 76, no. 7 (2021): 1676–88. http://dx.doi.org/10.1093/jac/dkab091.

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Abstract Background Antibiotic use is the most important modifiable risk factor for healthcare facility-associated Clostridioides difficile infection (HCFA-CDI). Previous systematic reviews cover studies published until 31 December 2012. Objectives To update the evidence for associations between antibiotic classes and HCFA-CDI to 31 December 2020. Methods PubMed, Scopus, Web of Science Core Collection, WorldCat and Proquest Dissertations & Theses were searched for studies published since 1 January 2013. Eligible studies were those conducted among adult hospital inpatients, measured exposur
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Alfred Maroyi. "Maerua edulis (Gilg & Gilg-Ben.) DeWolf: A review of its ethnomedicinal uses, phytochemistry and pharmacological properties." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 5089–96. http://dx.doi.org/10.26452/ijrps.v11i4.3106.

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Maerua edulis (Gilg & Gilg-Ben.) DeWolf is collected from the wild for its edible fruits and also used as traditional medicine. This study is aimed at evaluating the ethnomedicinal uses, phytochemistry and pharmacological properties of M. edulis. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. This study revealed that the bark, fruit, leaf, root and tuber infusion and decoction o
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Alfred Maroyi. "Maerua juncea Pax and M. schinzii Pax (Capparaceae): A comparative analysis of their ethnobotany and ethnomedicinal uses." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 6017–22. http://dx.doi.org/10.26452/ijrps.v11i4.3266.

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Maerua juncea Pax and M. schinzii Pax have a long history of medicinal use in southern Africa. This study aimed to review the ethnomedicinal uses, phytochemistry and pharmacological properties of the two species. Results of this study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. The leaves, roots, stems or whole plant parts of M. juncea and M. schinzii are mainly used as protective charm and tonic, and tradit
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Alfred Maroyi. "Cussonia natalensis Sond. and C. zuluensis Strey (Araliaceae): A comparative analysis of their medicinal uses and pharmacological properties." International Journal of Research in Pharmaceutical Sciences 11, no. 4 (2020): 6089–94. http://dx.doi.org/10.26452/ijrps.v11i4.3280.

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Cussonia natalensis Sond. and C. zuluensis Strey have a long history of medicinal use in southern Africa. The aim of this study was to review the medicinal uses and pharmacological properties of the two species. Results of this study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. The bark, fruits and roots of C. natalensis and C. zuluensis are used as emetic, purgative and protective charm, and traditional medi
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Dissertations / Theses on the topic "Dissertations – Pharmacology"

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Wild, Kenneth Douglas. "Pharmacology of opioid delta and kappa receptor subtypes." Diss., The University of Arizona, 1993. http://hdl.handle.net/10150/186489.

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The central hypothesis of this dissertation is that agonists acting at opioid δ or κ (but not μ) receptors may be useful for the production of effective pain relief with decreased incidence of side-effects, as well as for the possible treatment of drug-addiction. This dissertation focused on differentiating subtypes of the δ as well as the κ opioid receptor to provide selective targets for drug-development. Studies of the opioid δ receptor in vivo indicated that agonists at opioid δ receptor subtypes (δ₁ and δ₂) may produce antinociception via activation of different second messenger pathways.
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Kalappa, Bopanna Iythichanda. "THE MECHANISMS AND PHARMACOLOGY OF NEURONAL NICOTINIC ACETYLCHOLINE RECEPTORS IN THE CENTRAL NERVOUS SYSTEM." OpenSIUC, 2012. https://opensiuc.lib.siu.edu/dissertations/475.

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Neuronal nicotinic acetylcholine receptors (nAChRs) are key players in both cognitive and autonomic processes. In the cognitive domains of the brain, destruction of cholinergic inputs or disruption of nAChR function result in cognitive deficits as observed in Alzheimer's disease, schizophrenia, brain trauma and aging. By contrast, moderate activation of nAChRs supports neuroprotection and improves cognitive functions. In addition, neuronal nAChRs are also expressed in important autonomic centers such as the nucleus of the solitary tract (NTS) and the dorsal motor nucleus of the vagus (DMV) tha
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Samimi, Goli. "The cellular pharmacology and cytotoxic activity of cisplatin are modulated by the copper transporter ATP7A /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2004. http://wwwlib.umi.com/cr/ucsd/fullcit?p3123664.

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Slimano, Florian. "Pharmacologie et pharmacocinétique du peptide YSNSG." Thesis, Reims, 2018. http://www.theses.fr/2018REIMP202/document.

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Le peptide YSNSG est un cyclopeptide antagoniste de l’intégrine alpha v beta 3 actif par inhibition de la migration tumorale et de l'angiogénèse. Ces propriétés ont été démontrées in vitro sur diverses lignées cellulaires et in vivo chez des souris C57BL/6 avec xénogreffe de mélanome. Nos travaux se sont intéressés à la pharmacologie et à la pharmacocinétique du YSNSG. Dans un premier temps, nous avons étudié sa pharmacocinétique plasmatique et tissulaire (cerveau et sous-cutané) chez des rats Wistar en utilisant la microdialyse tissulaire. Elle a permis la détermination des principaux paramèt
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Gnabre, Jean-Noel. "Antiallergic activity of Tylophora sylvatica." Diss., The University of Arizona, 1991. http://hdl.handle.net/10150/185425.

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Tylophora sylvatica is a medicinal plant successfully used in African folk medicine for the management of various allergic conditions. This plant was investigated using screening methods suitable for the isolation of the active constituents which inhibit the release of chemical mediators of allergic reactions. Chromatographic studies led to the characterization of two classes of active principles: known fatty acids (oleic, linoleic and linolenic acids) with 0.064% yield; two novel glycosides, tylophoroside and acetyltylophoroside, having 0.008% and 0.0113% yields, respectively. Mild acidic hyd
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Henderson, Alden Keith. "Characterization of the cloned neurokinin A receptor transfected in murine fibroblasts." Diss., The University of Arizona, 1992. http://hdl.handle.net/10150/185828.

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The neurokinins comprise a family of peptides with similar structure and physiological effects. Several limitations arise when investigating their biochemical and pharmacological properties. Because neurokinins contain similar amino acids in their carboxyl terminus, radiolabeled neurokinins and biosynthesized antibodies may lack the specificity to distinguish between the various neurokinin receptors. Tissue preparations used to characterize their pharmacological responses often have several types of neurokinin receptors, different receptor densities, or signal transduction mechanisms. These fa
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Witt-Enderby, Paula Ann. "Bronchodilator effects on mechanisms involved in airway responsiveness." Diss., The University of Arizona, 1993. http://hdl.handle.net/10150/186353.

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The traditional approach to treating asthma includes the use of bronchodilator drugs, in particular β₂-adrenergic agonists and anti-cholinergics. It has been shown clinically that regularly scheduled use of both types of bronchodilators may result in a worsening of asthma. This dissertation evaluates the pulmonary effects of long-term bronchodilator administration in our animal model, the rabbit, at the level of the β-adrenergic receptor (βAR) and muscarinic cholinergic receptor (mAChR) located on airway smooth muscle. A four week infusion of the β₂ agonist bronchodilator, albuterol (6 mg/kg/d
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Bauman, Patricia Ann. "Interactions of mitoxantrone with cytokeratin in human and murine tumor cells." Diss., The University of Arizona, 1993. http://hdl.handle.net/10150/186357.

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The prolonged intracellular retention of the anti-cancer drug mitoxantrone has been linked to its cytotoxicity by several investigators. The persistent association of mitoxantrone with intermediate filament cytokeratin proteins was likewise observed, and its relationship to drug cytotoxicity was investigated. To test whether this association was indicative of mitoxantrone damage to cytokeratin, human WiDr/S colon carcinoma cells or mitoxantrone-resistant WiDr/R cells were treated with mitoxantrone and isolated cytokeratins were examined. Although an affinity of mitoxantrone for cytokeratin pro
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Clark, David Albert. "The effect of protease inhibitors and gastrin releasing peptide receptor antagonists on human small cell lung cancer growth." Diss., The University of Arizona, 1993. http://hdl.handle.net/10150/186391.

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The effect of the protease inhibitors BBI and aprotinin on the in vitro clonal growth of two human small cell lung cancer (SCLC) cell lines was investigated. Also, the effect of BBI on processing of proGRP and on mRNA levels for prohormone convertase 1 and 2 (PC1 and PC2) in SCLC cells was examined. Finally, the in vivo distribution of a BN/GRP receptor antagonist in mice was studied. In vitro growth of NCI-H345 and NCI-N592 SCLC cells was inhibited by the protease inhibitors BBI and aprotinin. When NCI-H345 cells were incubated with BBI and BN in the same plates, the addition of BN appeared t
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Daller, John Alfons. "Protein kinase C signal transduction in liver cell proliferation following partial hepatectomy." Diss., The University of Arizona, 1994. http://hdl.handle.net/10150/186650.

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Following partial hepatectomy, a complex series of biochemical and molecular events culminate in hepatocyte proliferation. These events proceed through a number of signal transduction mechanisms, including protein kinase C. The hypothesis of this research project was that the mitogenic signals induced by partial hepatectomy are transduced through protein kinase C activation and that this mechanism is an integral component of the signal transduction pathways culminating in hepatocyte proliferation. After preliminary toxicologic evaluation, we employed nontoxic doses of suramin, a relatively spe
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