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Journal articles on the topic 'Distal targeting device'

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1

Tyropoulos, Sarantis, and Christos Garnavos. "A new distal targeting device for closed interlocking nailing." Injury 32, no. 9 (2001): 732–35. http://dx.doi.org/10.1016/s0020-1383(01)00021-3.

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2

Wong, Tze-Hong, Meng-Shiue Lee, Sung-Yueh Wu, et al. "Novel Passive Two-Stage Magnetic Targeting Devices for Distal Locking of Interlocking Nails." Journal of Healthcare Engineering 2017 (2017): 1–11. http://dx.doi.org/10.1155/2017/3619403.

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Interlocking nailing is a common surgical operation to stabilize fractures in long bones. One of the difficult parts of the surgery is how to locate the position and direction of a screw hole on the interlocking nail, which is invisible to the naked eye after insertion of the nail into the medullary canal. Here, we propose a novel two-stage targeting process using two passive magnetic devices to locate the position and direction of the screw hole without radiation for the locking screw procedure. This involves a ring-shape positioning magnet inside the nail to generate a magnetic field for tar
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3

Ehlinger, M., G. Dillman, J. Czekaj, et al. "Distal targeting device for long Gamma nail®. Monocentric observational study." Orthopaedics & Traumatology: Surgery & Research 99, no. 7 (2013): 799–804. http://dx.doi.org/10.1016/j.otsr.2013.06.006.

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4

Antonini, Guido, Wilfried Stuflesser, Cornelio Crippa, and Georgios Touloupakis. "A distal-lock electromagnetic targeting device for intramedullary nailing: Suggestions and clinical experience." Chinese Journal of Traumatology 19, no. 6 (2016): 358–61. http://dx.doi.org/10.1016/j.cjtee.2016.06.010.

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5

Negrin, Lukas L., and Vilmos Vécsei. "Is a Magnetic-Manual Targeting Device an Appealing Alternative for Distal Locking of Tibial Intramedullary Nails?" Archives of Trauma Research 2, no. 1 (2013): 16–20. http://dx.doi.org/10.5812/atr.10638.

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6

Yoo, Jun-Il, Hojin Jeong, Jaeboem Na, et al. "Comparison of intraoperative radiation exposure with and without use of distal targeting device: a randomized control study." Archives of Orthopaedic and Trauma Surgery 139, no. 11 (2019): 1579–86. http://dx.doi.org/10.1007/s00402-019-03238-z.

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7

Gugala, Zbigniew, Arvind Nana, and Ronald W. Lindsey. "Tibial intramedullary nail distal interlocking screw placement: comparison of the free-hand versus distally-based targeting device techniques." Injury 32 (December 2001): 21–25. http://dx.doi.org/10.1016/s0020-1383(01)00115-2.

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8

Negrin, L. L., and V. Vécsei. "L-T3.4 Evaluation of an innovative combined magnetic and manual targeting device for distal locking of intramedullary nails." Injury 43 (September 2012): S6. http://dx.doi.org/10.1016/s0020-1383(12)70024-4.

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9

Anastopoulos, George, Panagiotis G. Ntagiopoulos, Dionisios Chissas, et al. "Evaluation of the Stryker S2™ IM Nail Distal Targeting Device for reduction of radiation exposure: A case series study." Injury 39, no. 10 (2008): 1210–15. http://dx.doi.org/10.1016/j.injury.2008.04.020.

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10

Patel, Nikunj K., Puneet Plaha, and Steven S. Gill. "Magnetic Resonance Imaging-Directed Method for Functional Neurosurgery Using Implantable Guide Tubes." Operative Neurosurgery 61, suppl_5 (2007): ONS358—ONS366. http://dx.doi.org/10.1227/01.neu.0000303994.89773.01.

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Abstract Objective: We present a magnetic resonance imaging-directed stereotactic system using implantable guide tubes for targeting deep brain nuclei in functional neurosurgery. Methods: Our method relies on visualization of the deep brain nuclei on high-resolution magnetic resonance images that delineate the target boundaries and enable direct targeting of specific regions of the nucleus. The delivery system comprises a modified stereoguide capable of delivering an implantable guide tube to the vicinity of the desired target. The guide tube (in-house investigational device) has a hub at its
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11

Zacharoulis, Stergios, Luca Szalontay, Dominic Higgins, et al. "DDEL-07. A PHASE I STUDY EXAMINING THE FEASIBILITY OF INTERMITTENT CONVECTION-ENHANCED DELIVERY (CED) OF MTX110 FOR THE TREATMENT OF CHILDREN WITH NEWLY DIAGNOSED DIFFUSE MIDLINE GLIOMAS." Neuro-Oncology 22, Supplement_3 (2020): iii284—iii285. http://dx.doi.org/10.1093/neuonc/noaa222.042.

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Abstract Convection-enhanced delivery (CED, the infusion of drugs under controlled pressure to the brain parenchyma via targeted micro-catheters, allows accurate anatomical targeting and delivery of higher (therapeutic) drug concentrations through clinically relevant volumes of brain tissue or tumor. Histone deacetylase inhibitors have been found in vitro to be the most active agents against Diffuse Midline Gliomas (DMGs) Using a novel device (implantable subcutaneous pump connected with catheter directly implanted into the pons/thalamus) we are performing a Phase I safety study of repeated in
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12

Sharif, Amnah, Ann Shaji, May Chammaa, Eileen Pawlik, and Rodrigo Fernandez-Valdivia. "Notch Transduction in Non-Small Cell Lung Cancer." International Journal of Molecular Sciences 21, no. 16 (2020): 5691. http://dx.doi.org/10.3390/ijms21165691.

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The evolutionarily-conserved Notch signaling pathway plays critical roles in cell communication, function and homeostasis equilibrium. The pathway serves as a cell-to-cell juxtaposed molecular transducer and is crucial in a number of cell processes including cell fate specification, asymmetric cell division and lateral inhibition. Notch also plays critical roles in organismal development, homeostasis, and regeneration, including somitogenesis, left-right asymmetry, neurogenesis, tissue repair, self-renewal and stemness, and its dysregulation has causative roles in a number of congenital and ac
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13

Rahman, Ruman, Stuart Smith, Cheryl Rahman, and Richard Grundy. "Antiangiogenic Therapy and Mechanisms of Tumor Resistance in Malignant Glioma." Journal of Oncology 2010 (2010): 1–16. http://dx.doi.org/10.1155/2010/251231.

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Despite advances in surgery, radiation therapy, and chemotherapeutics, patients with malignant glioma have a dismal prognosis. The formations of aberrant tumour vasculature and glioma cell invasion are major obstacles for effective treatment. Angiogenesis is a key event in the progression of malignant gliomas, a process involving endothelial cell proliferation, migration, reorganization of extracellular matrix and tube formation. Such processes are regulated by the homeostatic balance between proangiogenic and antiangiogenic factors, most notably vascular endothelial growth factors (VEGFs) pro
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14

Kato, Shunsuke. "Tumour-Agnostic Therapy for Pancreatic Cancer and Biliary Tract Cancer." Diagnostics 11, no. 2 (2021): 252. http://dx.doi.org/10.3390/diagnostics11020252.

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The prognosis of patients with solid tumours has remarkably improved with the development of molecular-targeted drugs and immune checkpoint inhibitors. However, the improvements in the prognosis of pancreatic cancer and biliary tract cancer is delayed compared to other carcinomas, and the 5-year survival rates of distal-stage disease are approximately 10 and 20%, respectively. However, a comprehensive analysis of tumour cells using The Cancer Genome Atlas (TCGA) project has led to the identification of various driver mutations. Evidently, few mutations exist across organs, and basket trials ta
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15

Tucker, Erik I., Ulla M. Marzec, Philberta Y. Leung, et al. "Apple Domain-Specific Anti-Factor XI Antibodies Inhibit Venous-Type Thrombosis with Improved Hemostatic Safety Profiles Compared to Enoxaparin in Primates." Blood 118, no. 21 (2011): 1173. http://dx.doi.org/10.1182/blood.v118.21.1173.1173.

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Abstract Abstract 1173 Severe inherited factor XI (FXI) deficiency decreases the risk of ischemic thromboembolic stroke and deep vein thrombosis, but can also cause bleeding in some patients. We therefore sought to further explore the roles of FXI in hemostasis and thrombosis in a baboon model, utilizing the anticoagulant monoclonal antibodies 14E11 and 1A6 that target specific functional domains of FXI. The 14E11 antibody binds to the apple 2 domain of FXI and inhibits FXI activation by factor XIIa (FXIIa), while not significantly inhibiting its activation by thrombin or the ability of FXIa t
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16

Thormann, Maximilian, Anastasios Mpotsaris, and Daniel Behme. "Treatment of a middle cerebral artery bifurcation aneurysm with the novel Contour Neurovascular System compatible with 0.021″ catheters." Neuroradiology Journal, August 23, 2021, 197140092110415. http://dx.doi.org/10.1177/19714009211041523.

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Background For wide-necked intracranial aneurysms, endo-saccular flow disruption can be a viable alternative to coiling or flow diverters. The Contour Neurovascular System is an intrasaccular flow diverter device targeting the neck of the aneurysm. Until now, the system had to be delivered through a 0.027″ microcatheter. We report the first implantation and follow-up of the novel Contour 021 system compatible with 0.021″ microcatheters. Case presentation: A 54-year-old male patient presented with an unruptured right middle cerebral artery aneurysm at the right temporopolar branch. Existing med
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17

Payne, Sophie C., Nicole M. Wiedmann, Calvin D. Eiber, et al. "Recording of Electrically Evoked Neural Activity and Bladder Pressure Responses in Awake Rats Chronically Implanted With a Pelvic Nerve Array." Frontiers in Neuroscience 14 (December 17, 2020). http://dx.doi.org/10.3389/fnins.2020.619275.

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Bioelectronic medical devices are well established and widely used in the treatment of urological dysfunction. Approved targets include the sacral S3 spinal root and posterior tibial nerve, but an alternate target is the group of pelvic splanchnic nerves, as these contain sacral visceral sensory and autonomic motor pathways that coordinate storage and voiding functions of the bladder. Here, we developed a device suitable for long-term use in an awake rat model to study electrical neuromodulation of the pelvic nerve (homolog of the human pelvic splanchnic nerves). In male Sprague-Dawley rats, c
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18

Almallouhi, Eyad, Sami Al kasab, Ali Alawieh, et al. "Abstract TP12: The Trend of Successful First Pass in M2 Segment Stroke Thrombectomy- Insights From the STAR Collaboration." Stroke 51, Suppl_1 (2020). http://dx.doi.org/10.1161/str.51.suppl_1.tp12.

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Introduction: Stroke thrombectomy devices and the experience of neurointerventionists have improved significantly over the last few years making targeting distal occlusions such as of the M2 segment of the middle cerebral artery more feasible. We aimed to study the trend in the successful first pass (SFP) of M2 occlusions over time using the data from a contemporary multicenter registry. Methods: We reviewed the data from the Stroke Thrombectomy and Aneurysm Registry (STAR), which included data from 11 thrombectomy-capable stroke centers to identify stroke patients who underwent mechanical thr
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19

Corie, Thomas H., and Steven K. Charles. "Simulated Tremor Propagation in the Upper Limb: From Muscle Activity to Joint Displacement." Journal of Biomechanical Engineering 141, no. 8 (2019). http://dx.doi.org/10.1115/1.4043442.

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Although tremor is the most common movement disorder, there are few noninvasive treatment options. Creating effective tremor suppression devices requires a knowledge of where tremor originates mechanically (which muscles) and how it propagates through the limb (to which degrees-of-freedom (DOF)). To simulate tremor propagation, we created a simple model of the upper limb, with tremorogenic activity in the 15 major superficial muscles as inputs and tremulous joint displacement in the seven major DOF as outputs. The model approximated the muscle excitation–contraction dynamics, musculoskeletal g
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