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1

Öström, Linn. "Post-processingof Monte Carlo calculated dose distributions." Thesis, KTH, Matematisk statistik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-244314.

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This Master Thesis focuses on denoising of Monte Carlo calculated dose distributions of radiosurgery treatment plans. The objective of this project is to implement a Denoising Autoencoder (DAE) and investigate its denoising performance when it has been trained on Monte Carlo calculated dose distributions generated with lower number of photon showers. The DAE is trained in a supervised setting to learn the mapping between corrupted observations and clean ones. The questions this thesis aims to answer are: (i) Can a DAE be used to denoise Monte Carlo calculated dose distributions, and thus predi
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2

Milette, Marie-Pierre. "Direct optimization of 3D dose distributions using collimator rotation." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/274.

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The primary goal of this thesis is to improve the precision and efficiency of radiation therapy treatment. This goal is achieved by developing and implementing a direct aperture optimization (DAO) platform where the multileaf collimator (MLC) is rotated between each aperture. The approach is referred to as rotating aperture optimization (RAO). A series of tests is performed to evaluate how a final optimized plan depends on MLC parameters. Imposing constraints on the leaf sequence results in increased efficiency and a simplification of the treatment plan without compromising the quality of the
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3

Nilsson, Viktor. "Prediction of Dose Probability Distributions Using Mixture Density Networks." Thesis, KTH, Matematisk statistik, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-273610.

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In recent years, machine learning has become utilized in external radiation therapy treatment planning. This involves automatic generation of treatment plans based on CT-scans and other spatial information such as the location of tumors and organs. The utility lies in relieving clinical staff from the labor of manually or semi-manually creating such plans. Rather than predicting a deterministic plan, there is great value in modeling it stochastically, i.e. predicting a probability distribution of dose from CT-scans and delineated biological structures. The stochasticity inherent in the RT trea
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4

Tozer-Loft, Stephen M. "Dose volume analysis in brachytherapy and stereotactic radiosurgery." Thesis, University of Sheffield, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366100.

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5

Fox, Timothy Harold. "Computation and optimization of dose distributions for rotational stereotactic radiosurgery." Diss., Georgia Institute of Technology, 1994. http://hdl.handle.net/1853/32843.

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6

South, Christopher Peter. "The use of functional imaging to design optimal radiotherapy dose distributions." Thesis, Institute of Cancer Research (University Of London), 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538528.

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7

CECILIO, PAULO J. "Implementacao e aceite de sistema de radioterapia de feixe modulado dinamico com o uso de colimador secundario de multiplas folhas." reponame:Repositório Institucional do IPEN, 2008. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11757.

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8

Rowbottom, Carl Graham. "Optimisation of beam-orientations in conformal radiotherapy treatment planning." Thesis, Institute of Cancer Research (University Of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314088.

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9

Doucet, Robert. "Experimental verification of Monte Carlo calculated dose distributions for clinical electron beams." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33750.

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Current electron beam treatment planning algorithms are inadequate to calculate dose distributions in heterogeneous phantoms. Fast Monte Carlo algorithms are accurate in general but their clinical implementation needs validation. Calculations of electron beam dose distributions performed using the fast Monte Carlo system XVMC and the well-benchmarked general-purpose Monte Carlo code EGSnrc were compared with measurements. Irradiations were performed using the 9 MeV and 15 MeV beams from the Clinac 18 accelerator with standard conditions. Percent depth doses and lateral profiles were measured w
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10

Hellström, Terese. "Deep-learning based prediction model for dose distributions in lung cancer patients." Thesis, Stockholms universitet, Fysikum, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-196891.

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Background To combat one of the leading causes of death worldwide, lung cancer treatment techniques and modalities are advancing, and the treatment options are becoming increasingly individualized. Modern cancer treatment includes the option for the patient to be treated with proton therapy, which can in some cases spare healthy tissue from excessive dose better than conventional photon radiotherapy. However, to assess the benefit of proton therapy compared to photon therapy, it is necessary to make both treatment plans to get information about the Tumour Control Probability (TCP) and the Norm
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11

Robar, James L. "Film dosimetry and three-dimensional verification of conformal dose distributions in stereotactic radiosurgery." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape3/PQDD_0019/NQ48701.pdf.

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12

Gillespie, Timothy James. "A computer model of beta particle dose distributions in lithium fluoride and tissue." Thesis, Georgia Institute of Technology, 1994. http://hdl.handle.net/1853/16952.

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13

Fragoso, Margarida. "Application of Monte Carlo techniques for the calculation of accurate brachytherapy dose distributions." Thesis, Institute of Cancer Research (University Of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.413609.

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14

Bero, Mamdouh A. "Development of a three-dimensional radiation dosimetry system." Thesis, University of Surrey, 2001. http://epubs.surrey.ac.uk/719/.

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15

SCAFF, LUIZ A. M. "Metodo de calculo de dose na irradiacao de todo o corpo com raios gama do cobalto-60." reponame:Repositório Institucional do IPEN, 2001. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10901.

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16

MADUAR, MARCELO F. "Determinacao de fatores de conversao de dose para radiacao gama externa em residencias." reponame:Repositório Institucional do IPEN, 2000. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10816.

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17

Belanger, Philippe. "MR based frickle-gelatin dosimetry : uncertainty evaluation and computerised analysis of measured dose distributions." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=32759.

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Dynamically delivered intensity modulated beams (IMBs) pose unique verification problems that may be addressed with the use of integrating continuous 3D dosimeters such as gel based Fricke dosimeters. Accurate knowledge of the ability of these dosimeters to measure adequately and precisely the delivered dose is a prerequisite for their clinical use. The magnetic properties of the ferrous and ferric ions present in the gel based Fricke dosimeter after its irradiation are the basis for the use of magnetic resonance imaging (MRI) in the measurement of dose. This thesis presents the investigation
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18

Nilsson, Kenneth A. "Simulating Accidental Exposures to deliberate Intrusions in Pipe Networks." University of Cincinnati / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1091122400.

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19

Popov, G. F., S. I. Savan, R. V. Lazurik, and A. V. Pochynok. "Selection of calculation methods for the analysis of absorbed depth-dose distributions of electron beams." Thesis, Sumy State University, 2016. http://essuir.sumdu.edu.ua/handle/123456789/46936.

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The work is dedicated to comparison methods of processing the results of measurements of the absorbed depth-dose distributions (DDD) of the electron radiation to determine the practical range of electrons. The sets of test data were obtained by modeling the DDD with use Monte Carlo method. The accuracy of the calculation method is determined by the mean square error of processing results the sets of test data. In the paper it was performed the comparison of computational methods of processing the measurement results that differs in the sizes of the array of data being processed and types of fu
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20

Dybwad, Anniken. "Comparison of Dose Distributions resulting from IMRT and VMAT, and Assessment of MLC Leaf Positioning Errors." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for fysikk, 2013. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-22432.

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Intensity-modulated radiotherapy (IMRT) is a radiation technique used in the treatment of head-and-neck cancer patients. IMRT results in a dose distribution which conforms to the tumor volume(s), and therefore sparing surrounding normal tissue. However, the radiation delivery is relatively time consuming. Volumetric modulated arc therapy (VMAT) on the other hand, has a radiation delivery time down to one third compared to that of IMRT (depending on number of arcs, arc lengths etc.). This shortened treatment time will allow more treatments per day, and a decrease in discomfort which may be exp
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21

Aydarous, Abdulkadir Sheikh. "Development of imaging techniques for determining dose distributions around discrete radioactive particles found in the environment." Thesis, University of Birmingham, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.415424.

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22

GONCALVES, VINICIUS D. "Caracterização da dose em pacientes devido a produção de imagem de raios-X utilizadas em radioterapia guiada por imagem - IGRT." reponame:Repositório Institucional do IPEN, 2014. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10555.

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23

Beauvais, March Hélène. "Modelisation des distributions de dose sur l'axe pour les faisceaux de photons de haute energie utilises en radiotherapie." Toulouse 3, 1987. http://www.theses.fr/1987TOU30074.

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24

Faria, Clara Maria Gonçalves de. "Distribuições de limiar de dose e suas causas e consequências em Terapia Fotodinâmica." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-18052017-083829/.

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O princípio de terapia fotodinâmica (TFD) foi introduzido por volta de 1900 mas posteriormente investgado como candidato para tratamento de cancer na década de 1970. Desde então, existem diversos trabalhos a respeito do assunto in vitro, in vivo e em estudos clínicos e grandes avanços foram alcançados. Entretanto, alguns desafios ainda não foram superados, como a variabilidade dos resultados. Este trabalho consiste na investigação de suas causas, em que o principal objetivo é avançar o estado da arte em TFD. Para isso foi usado um modelo de distribuição de limiar de dose para avaliar resistênc
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25

SILVA, ROSIANE A. da. "Dosimetria de filtros dinamicos aprimorados." reponame:Repositório Institucional do IPEN, 2006. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11368.

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26

ANGELOCCI, LUCAS V. "Estudo de casos clínicos em radioterapia através do sistema de planejamento AMIGOBrachy." reponame:Repositório Institucional do IPEN, 2016. http://repositorio.ipen.br:8080/xmlui/handle/123456789/26926.

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Submitted by Marco Antonio Oliveira da Silva (maosilva@ipen.br) on 2016-12-21T11:30:16Z No. of bitstreams: 0<br>Made available in DSpace on 2016-12-21T11:30:16Z (GMT). No. of bitstreams: 0<br>O sucesso de uma radioterapia depende do correto planejamento da dose a ser entregue ao volume alvo. Na braquiterapia, modalidade da radioterapia onde um radioisótopo selado é implantado intracavitariamente ou intersticialmente no paciente, há menos avanços em sistemas de planejamento de tratamento computacionais do que na teleterapia, amplamente mais utilizada nos serviços típicos. Porém, a braquiterapi
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27

Bergman, Alanah Mary. "Monte Carlo simulation of x-ray dose distributions for direct aperture optimization of intensity modulated treatment fields." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/30720.

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This thesis investigates methods of reducing radiation dose calculation errors as applied to a specialized x-ray therapy called intensity modulated radiation therapy (IMRT). There are three major areas of investigation. First, limits of the popular 2D pencil beam kernel (PBK) dose calculation algorithm are explored. The ability to resolve high dose gradients is partly related to the shape of the PBK. Improvements to the spatial resolution can be achieved by modifying the dose kernel shapes already present in the clinical treatment planning system. Optimization of the PBK shape based on m
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28

Rae, William Ian Duncombe. "Measured dose distributions of iodine-125 sources and the computerised optimisation of their positions in brachytherapy planning." Master's thesis, University of Cape Town, 1987. http://hdl.handle.net/11427/12732.

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Includes bibliographies.<br>The use of 1-125 seeds in brachytherapy is widespread and becoming increasingly varied. The spatial dose distributions around two types of 1-125 seeds in general use, were measured using a Geiger-Muller chamber. Seeds with the 1-125 adsorbed onto resin spheres had a 10% less anisotropic dose distribution than seeds containing a silver wire with the 1-125 adsorbed onto it. An interpolative method was developed for fast dose calculations taking this anisotropy into account.
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29

Ermeneux, Louis. "Dosimétrie des systèmes IRM-LINAC utilisés en radiothérapie externe : caractérisation des faisceaux et évaluation des distributions de dose." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASP005.

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L'IRM-LINAC est un appareil de radiothérapie guidée par l'imagerie combinant un accélérateur linéaire (LINAC) et un imageur par résonance magnétique (IRM), permettant un meilleur suivi de la tumeur. Des problématiques dosimétriques, associées à la présence du champ magnétique statique, ont été soulevées dans la littérature. L'objectif de la thèse est de développer des outils dosimétriques et des protocoles robustes utilisables sur les IRM-LINAC afin d'améliorer la connaissance des doses délivrées aux patients traités avec ces appareils. La première partie du travail se concentre sur la détermi
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30

CAVINATO, CHRISTIANNE C. "Padronizacao do metodo de dosimetria fricke gel e avaliacao tridimensional de dose empregando a tecnica de imageamento por ressonancia magnetica." reponame:Repositório Institucional do IPEN, 2009. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9406.

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31

MATSUSHIMA, LUCIANA C. "Determinação das curvas de isodose e confirmação do planejamento em Radioterapia de Intensidade Modulada - IMRT convencional empregando as técnicas de termoluminescência, luminescência opticamente estimulada e detectores semicondutores." reponame:Repositório Institucional do IPEN, 2015. http://repositorio.ipen.br:8080/xmlui/handle/123456789/23694.

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32

Trauernicht, Christoph Jan. "Measured and calculated dose distributions in the “claws” – a specially designed gold applicator loaded with I-125 seeds." Doctoral thesis, Faculty of Health Sciences, 2020. http://hdl.handle.net/11427/32371.

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Introduction: The “Claws” is a unique gold applicator for whole-eye radiotherapy that was designed at Groote Schuur Hospital. It is used to treat retinoblastoma. Under general anaesthesia, a pericorneal ring is attached to the four extraocular muscles, and four legs, each loaded with I125 seeds, are inserted beneath the conjunctiva in-between each pair of muscles and attached anteriorly to the ring. The four legs that are now sutured onto the ring give it a claw-like appearance, hence the name for the applicator. The applicator was designed in such a way that the dose is directed towards the m
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33

Beauvais, Hélène. "Modélisation des distributions de dose sur l'axe pour des faisceaux de photons de haute énergie utilisés en radiothérapie." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb37602672c.

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34

Helal, Azza Mahmoud. "The effect of patient anatomy on optimised intensity modulated radiotherapy dose distributions for head and neck and prostate cancer." Thesis, University of Nottingham, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.438639.

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35

Dejean-Viellard, Catherine. "Etude des techniques de régularisation en radiothérapie conformationnelle avec modulation d'intensité et évaluation quantitative des distributions de dose optimales." Toulouse 3, 2003. http://www.theses.fr/2003TOU30195.

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36

MIZUNO, ERICK Y. "Desenvolvimento e caracterização de um gel alanima para aplicação na medida da distribuição da dose de radiação usando a técnica de espectrofotometria." reponame:Repositório Institucional do IPEN, 2007. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11571.

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Cecilio, Paulo José. "Implementação e aceite de sistema de radioterapia de feixe modulado dinâmico com o uso de colimador secundário de múltiplas folhas." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/85/85131/tde-03052012-094138/.

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A radioterapia de feixe de intensidade modulada (IMRT) no seu modo dinâmico é uma forma de radioterapia tri-dimensional (3D), na qual modula-se um feixe de forma a obter-se a irradiação com campos que possuem perfil variável. Os campos são gerados por um sistema de otimização matemático e transformado em seqüências de movimento ou abertura de lâminas dos colimadores terciários de múltiplas folhas (MLC) ou feixe colimado helicoidal, reproduzindo a fluência de radiação adequada. No processo o operador atribui valores limitantes de dose ao alvo e aos órgãos de risco circunvizinhos para que o sist
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Deniz, Daniel. "Causes of multimodality of efficiency gain distributions in accelerated Monte Carlo based dose calculations for brachytherapy planning using correlated sampling." Thesis, Linköping University, Department of Biomedical Engineering, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-56468.

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<p>Fixed-collision correlated sampling for Monte Carlo (MC) simulations is a method which can be used in order to shorten the simulation time for brachytherapy treatment planning in a 3D patient geometry. The increased efficiency compared to conventional MC simulation is measured by efficiency gain. However, a previous study showed that, in some cases, PDFs (probability density functions) of estimates of the efficiency gain, simulated using resampling and other MC methods, were multimodal with values below 1. This means that the method was less effective than conventional sampling for these ca
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39

Moji, Kabelo McDonald. "Comparison of measured photon and electron beam dose distributions between 3D water phanton and profiler 2 scanning system, South Africa." Thesis, University of Limpopo (Medunsa Campus), 2013. http://hdl.handle.net/10386/1086.

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Thesis ( MSc ( Physics) ) -- University of Limpopo, 2013.<br>Background and Objectives: To establish whether the profiler 2 scanning system can be used as a substitute for the 3D-water phantom, by comparing the percentage depth doses and beam profiles for both the photons and electron beams, and validating the results using CMS XiO treatment planning system. Methods: Beam data (profiles, percentage depth doses and absolute dosimetry) were acquired for the two systems: (3D-water phantom and profiler 2 scanning system) for beam energies 6 MV and 15 MV photon beams, and 4, 6, 8, 10, 12 and
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40

Aryal, Prakash. "REEVALUATION OF THE AAPM TG-43 BRACHYTHERAPY DOSIMETRY PARAMETERS FOR AN 125I SEED, AND THE INFLUENCE OF EYE PLAQUE DESIGN ON DOSE DISTRIBUTIONS AND DOSE-VOLUME HISTOGRAMS." UKnowledge, 2014. http://uknowledge.uky.edu/physastron_etds/14.

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The TG-43 dosimetry parameters of the AdvantageTM 125I model IAI-125A brachytherapy seed were studied. An investigation using modern MCNP radiation transport code with updated cross-section libraries was performed. Twelve different simulation conditions were studied for a single seed by varying the coating thickness, mass density, photon energy spectrum and cross-section library. The dose rate was found to be 6.3% lower at 1 cm in comparison to published results. New TG-43 dosimetry parameters are proposed. The dose distribution for a brachytherapy eye plaque, model EP917, was investigated, in
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POLI, MARIA E. R. "Dosimetria aplicada na irradiacao de toda a pele utilizando feixes de eletrons com energia nominal de 4 MeV." reponame:Repositório Institucional do IPEN, 2000. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10813.

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GROPPO, DANIELA P. "Caracterização dosimétrica de amostras de BeO em feixes de radiação alfa, beta e X por técnicas luminescentes." reponame:Repositório Institucional do IPEN, 2013. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10576.

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Hepworth, Stephen J. "Investigations into polymer gel dosimetry using magnetic resonance imaging." Thesis, University of Surrey, 2000. http://epubs.surrey.ac.uk/978/.

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44

FERAUCHE, DEBORA C. "Desenvolvimento de um sistema de dosimetria in vivo por meio de filmes portals para o controle da qualidade de tratamentos radioterapeuticos." reponame:Repositório Institucional do IPEN, 2002. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11006.

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Taulbee, Timothy Dale. "Measurement and model prediction of proton-recoil track length distributions in NTA film dosimeters for neutron energy spectroscopy and retrospective dose assessment." Cincinnati, Ohio : University of Cincinnati, 2009. http://www.ohiolink.edu/etd/view.cgi?acc_num=ucin1235764236.

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Thesis (Ph.D.)--University of Cincinnati, 2009.<br>Advisors: Henry Spitz PhD (Committee Chair), Bingjing Su PhD (Committee Member), John Christenson PhD (Committee Member). Title from electronic thesis title page (viewed May 1, 2009). Keywords: NTA; proton-recoil; neutron spectroscopy; dose assessment; track length; Monte Carlo; neutron transport; neutron interactions. Includes abstract. Includes bibliographical references.
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Niemkiewicz, John. "A study on the use of removal-diffusion theory to calculate neutron distributions for dose determination in boron neutron capture therapy /." The Ohio State University, 1996. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487934589976468.

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FONSECA, GABRIEL P. "Projeto e construcao de placas espalhadoras e degradadoras de energia para uso em radioterapia com feixe de eletrons para doencas de pele." reponame:Repositório Institucional do IPEN, 2010. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9550.

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TADA, ARIANE. "Analise dosimetrica de fontes de radiacao para uso em lesoes dermatologicas." reponame:Repositório Institucional do IPEN, 2010. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9551.

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Albaret, Claude. "Automated system for Monte Carlo determination of cutout factors of arbitrarily shaped electron beams and experimental verification of Monte Carlo calculated dose distributions." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=81259.

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Dose predictions by Monte-Carlo (MC) techniques could alleviate the measurement load required in linac commissioning and clinical radiotherapy practice, where small or irregular electron fields are routinely encountered. In particular, this study focused on the MC calculation of cutout factors for clinical electron beams. A MC model for a Varian linac CL2300C/D was built and validated for all electron energies and applicators. A MC user code for simulation of irregular cutouts was then developed and validated. Supported by a home-developed graphical user interface, it determines in situ
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ANTUNES, PAULA C. G. "Reconstrucao de objetos simuladores segmentados aplicaveis a dosimetria de pele." reponame:Repositório Institucional do IPEN, 2010. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9614.

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