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1

Awassa, Jazia. "Mécanismes antibactériens des hydroxydes doubles lamellaires à base de zinc." Electronic Thesis or Diss., Université de Lorraine, 2022. http://www.theses.fr/2022LORR0155.

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Les hydroxydes doubles lamellaires (HDL) sont des composés solides constitués par un ensemble de feuilles d'hydroxydes métalliques divalents M(II) et trivalents M(III) entre lesquels s’insèrent des anions et des molécules d’eau. En raison de la flexibilité des HDL en termes de propriétés physico-chimiques, l’étude des différents mécanismes antibactériens qui leurs sont associés présente un intérêt croissant. Ce travail de thèse vise à étudier différentes hypothèses proposées pour explique l'effet antibactérien des hydroxydes doubles lamellaire (HDL) à base de zinc : (1) interactions directes e
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2

Wang, Yu-Wen. "Substitution of Calcium with Divalent Metal Ions in Paraoxonase I." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1420819949.

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3

Afolaranmi, Grace Ayodele. "Disposition of metal ions in patients after release from orthopaedic arthroplasties." Thesis, University of Strathclyde, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501856.

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4

Bellomo, Elisa. "Divalent metal ions and the pancreatic B-cell : role in the pathogenesis of type 2 diabetes." Thesis, Imperial College London, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.526394.

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5

Ferko, Maxime-Alexandre. "Molecular Mechanisms Involved in Interleukin-1β Release by Macrophages Exposed to Metal Ions from Implantable Biomaterials". Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/37331.

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Metal ions released from implantable biomaterials have been associated with adverse biological reactions that can limit implant longevity. Previous studies have shown that, in macrophages, Co2+, Cr3+, and Ni2+ can activate the NLR family pyrin domain-containing protein 3 (NLPR3) inflammasome, which is responsible for interleukin(IL)-1β production through caspase-1. Furthermore, these ions are known to induce oxidative stress, and inflammasome priming is known to involve nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling. However, the mechanisms of inflammasome act
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6

Liu, Chang. "Metal ions removal from polluted waters by sorption onto exhausted coffee waste. Application to metal finishing industries wastewater treatment." Doctoral thesis, Universitat de Girona, 2014. http://hdl.handle.net/10803/283705.

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A new technology for Cr(VI) and divalent metal ions removal based on metal sorption onto exhausted coffee waste has been developed. Physical and chemical characterization of exhausted coffee waste was explored as well as the role of structural and non structural compounds of the waste in metal ions sorption. Kinetics of Cr(VI) sorption from binary mixtures containing different Cr(VI) and Cu(II) molar ratios were carried out in a batch reactor. A synergistic effect of Cu(II) in Cr(VI) reduction and sorption was found. From the kinetic sets of data a kinetic model taking into account Cr(VI) redu
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7

Brännvall, Mathias. "Metal ion cooperativity in Escherichia coli RNase P RNA." Doctoral thesis, Uppsala universitet, Institutionen för cell- och molekylärbiologi, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2056.

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RNase P is an essential ribonuclease responsible for removal of the 5’ leader of tRNA precursors. Bacterial RNase P consists of an RNA subunit and a small basic protein. The catalytic activity is associated with the RNA subunit, i.e. bacterial RNase P RNA is a ribozyme. The protein subunit is, however, essential for activity in vivo. RNase P RNA, as well as the holoenzyme, requires the presence of divalent metal ions for activity. The aim of this thesis was to increase our understanding of the catalytic mechanism of RNase P RNA mediated cleavage. The importance of the nucleotides close to the
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8

Xiao, Lan. "Etude physico-chimique de la complexation de divers ions metalliques (cu**(2+), ni**(2+) et co**(2+)) avec des dipeptides l-l contenant des chaines laterales non-coordinantes." Paris 7, 1988. http://www.theses.fr/1988PA077170.

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Stabilite des complexes en fonction de l'interaction des chaines laterales du dipeptide et le solvant. Mesures potentiometriques calorimetriques, caracterisation spectrometrique et structure moleculaire
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9

Sahmoune, Amar. "Extractions synergiques de metaux divalents de transition par association d'une acyl-4-pyrazolone-5 avec des polyethers cycliques et acycliques." Université Louis Pasteur (Strasbourg) (1971-2008), 1988. http://www.theses.fr/1988STR13116.

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Extractions de co. Zu. Cd et cu divalents par les melanges phenyl-1 methyl-3 benzoyl-4 pyrazolone-5 ethers crown. La coextraction alcalins-alcalinoterreux complexes par les composes crown et des metaux divalents est possible quand la taille de la cavite de l'ether-crown est voisine de celle de l'alcalin (ou alcalino-terreux) et quand l'ion ml::(3)**(-) est suffisamment stable
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10

Dearden, David Vernell Beauchamp Jesse L. Beauchamp Jesse L. "Experimental probes of gas phase ions and molecules : I. Product kinetic energy release measurements as a probe of reaction thermochemistry, dynamics, and chemical structure in systems containing transition metal ions. II. Photoelectron and optical studies of organic transient species /." Diss., Pasadena, Calif. : California Institute of Technology, 1989. http://resolver.caltech.edu/CaltechETD:etd-02082007-130036.

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11

Diantouba, Bertin Aimé. "Effets structuraux des acyl-4-pyrazolones-5 dans l'extraction liquide-liquide des cations metalliques divalents." Université Louis Pasteur (Strasbourg) (1971-2008), 1988. http://www.theses.fr/1988STR13093.

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Etude de l'effet de l'acidite de la lipophilie et effets structuraux des acyl-4 pyrazolones-5 dans l'extraction de cu, co, zu et pb divalents. Extraction de 3 types de complexes metalliques : mononucleaires de type m(l-n-lh)::(2) ou m(l-n-l) et polynucleaires (m(l-n-l))::(j). Meilleures possibilites des bis-acyl-4 pyrazolones-5
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12

Navick, Caldentey Martine. "Contribution à l'étude des phénomènes de synergie en extraction liquide-liquide : application à l'extraction du nickel(II) et du cobalt(II) en milieu acide." Paris 6, 1986. http://www.theses.fr/1986PA066297.

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Etude des propriétés d'agent d'extraction des acides di(alkyl)dithiophosphoriques ; ils ne peuvent pas être utilisés industriellement car ils s'hydrolysent rapidement au contact d'une phase aqueuse des 35**(o). En fait il semble que les anions di(alkyl) monothiophosphoriques conviennent, utilises en même temps qu'une oxime. Effet de divers facteurs sur la cinétique d'extraction. On peut séparer à ph1, ni et co par une extraction par acide di(ethyl)monothiophosphorique et quinoleinols-8 substitués.
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13

Fichou, Denis. "L'interface oxyde de zinc/électrolyte : étude des processus primaires." Paris 6, 1986. http://www.theses.fr/1986PA066259.

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14

LAKKIS, ZAHREDDINE ZEINAB. "Aspects thermodynamiques et cinetiques de l'extraction de metaux divalents par des acyl-4-pyrazolones-5." Strasbourg 1, 1986. http://www.theses.fr/1986STR13001.

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Extraction de cd et zn a partir des milieux aqueux, perchlorate, nitrate et sulfate par des melanges de phenyl-1 methyl-3 benzoyl-4 pyrazolone-5 et de sels d'ammonium lipophiles. Le pyrazolonate de nh::(4) est l'agent reel de synergie. Mecanisme de transport de cuivre par des acyl-4 pyrazolones-5 a travers une membrane liquide epaisse
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15

Vasconcelos, Glenda Lara Lopes. "Efeito das pastilhas higienizadoras efervescentes à base de peróxido alcalino em liga metálica de cobalto-cromo." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/58/58131/tde-15032016-162731/.

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A higienização das próteses é de fundamental importância para a longevidade do tratamento reabilitador. Entretanto, é necessário analisar os efeitos que os higienizadores podem causar nas superfícies que compõem uma prótese. Deste modo, o objetivo deste estudo foi avaliar os efeitos de pastilhas efervescentes à base de peróxido alcalino em liga de cobalto cromo (Co-Cr), utilizada em Prótese Parcial Removível (PPR). A partir de uma matriz metálica, padrões de cera em forma de disco (12 mm x 3 mm) foram confeccionados para posterior fundição. Os espécimes metálicos (n=16) foram imersos nas soluç
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16

Ben, Nasr Chérif. "Complexation du nickel (II) et des lanthanides (III) par des phosphoramides bidentes : Application à l'extraction liquide-liquide." Nancy 1, 1986. http://www.theses.fr/1986NAN10032.

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Les composés de type (NME::(2))::(2)P(O)NRP(O)(NME::(2))::(2) complexent fortement lésions métalliques et peuvent être utilisés en tant qu'agents extractaires dans l'extraction liquide liquide. Synthèse systématique des complexes lanthanides-NDA. L'étude RMN a permis également de trier les contributions de contact et de pseudo-contact au déplacement paramagnétique des protons et des phosphores du ligand engagé dans le complexe et d'obtenir des informations concernant la structure des complexes en solution. Enfin, le problème de l'extraction liquide-liquide des lanthanides par le NIPA dans le n
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17

Senapati, Bhagyashree. "Biophysical and Catalytic Characterization of Gpx7 in Presence Divalent Metal Ions." Thesis, 2015. http://ethesis.nitrkl.ac.in/7228/1/Biophysical_Senapati_2015.pdf.

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Glutathione peroxidase (GPx) is a family of proteins found in biological systems. The protein family is known to detoxicate the system by scavenging reactive oxygen species, formed upon interaction of the system with external moieties or stress conditions or normally synthesized during metabolism of the system. Out of all members of the family, GPx4 and 7 stand alone because of their action on lipid peroxides. GPx4 and 7 are known to reduce lipid peroxides present in lipid membrane into respective lipid alcohol, hence saving the membrane from depolarization. Besides GPx7, other proteins (GPx1-
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18

Thuy, Nguyen Thi Dieu, and 阮妙翠. "Solution equilibria of complex formation between caffeic acid, dihydrocaffeic acid and divalent metal ions." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/52211824435701487927.

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碩士<br>國立臺灣科技大學<br>化學工程系<br>103<br>The solution equilibria between chelating agents (caffeic acid – CA or dihydrocaffeic acid – DCA) and several divalent metal ions (Cu2+, Zn2+, Ni2+, Co2+ and Mn2+) in binary and ternary systems were investigated in this work. The potentiometric measurement was carried out at 37oC and ionic strength 0.15 mol.dm-3 NaCl in order to determine the protonation and formation constants of complexes. The complexation model and speciation diagram were established by computer programs Hyperquad2008 and HySS, respectively. Moreover, UV – Vis spectrophotometry was performe
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19

NGUYEN, LOC QUANG, and 阮光祿. "Effects of Divalent Metal Ions on the Activity of Recombinant Drosophila Melanogaster Tyrosylprotein Sulfotransferase." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/t2eg64.

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碩士<br>國立交通大學<br>生物科技學系<br>107<br>Protein tyrosine sulfation (PTS) is a common post-translational modification. 875 among 4256 proteins have been identified to undergo the PTS on their tyrosine residues. Tyrosylprotein sulfotransferase (TPST; Enzyme Commission number: 2.8.2.20) is the type II trans-Golgi membrane enzyme responsible for the PTS, delineating the transfer of the sulfonate group (SO3)- to specific tyrosine residues in target peptides/proteins to form O-sulfation compound. The sulfation activity plays essential roles in pathogen infection, hemostasis and protein–protein interactions
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20

Hung, Hui Chih, and 洪慧芝. "The inhibitory effect of divalent metal ions on human placental alkaline phosphatase in reverse micelles." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/49724713477618096479.

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碩士<br>國防醫學院<br>生物化學研究所<br>83<br>Human placental alkaline phosphatase (EC 3. 1. 3. 1.) is an integral membrane protein; catalyzing the hydrolysis of phosphoester linkage of a broad range substrate. It is a dimeric metalloprotein possessing two zinc atoms and a magnesium atom at eath active site. In aqueous solution, Mg2+ was found to be a nonessential activator for the enzyme. We have embedded human placental alkaline phosphatase in a reverse micellar system prepared
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21

Lee, Nung, and 李儂. "Electrochemical Behaviors of Divalent Metal Ions and Nanoporous Activated Carbon Electrodes in Capacitive Deionization Process." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/34218001253688825604.

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碩士<br>國立臺灣大學<br>環境工程學研究所<br>104<br>Capacitive deionization (CDI) is a novel water purification technology for the removal of ions with the features of low-energy consumption, no membrane component, no secondary waste, and easy regeneration of electrodes (Anderson et al. 2010). The working principle of the CDI system is to apply an external electric field on a pair of porous carbon electrodes, and thereby ions can be electrostatically captured onto the oppositely charged electrode surface. Notably, our previous study reported that copper ions can be effectively removed from solutions by electro
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22

Yoshida, Aiichiro. "Catalytic mechanism of the tetrahymena ribozyme : the role of divalent metal ions in the catalysis /." 2000. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:9965041.

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23

Poyner, Russell R. "The role of divalent metal ions in the reaction catalyzed by yeast enolase a spectroscopic study /." 1993. http://catalog.hathitrust.org/api/volumes/oclc/31403479.html.

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24

Shou-YunLu та 盧守筠. "Site-Directed Mutagenesis Studies on the Divalent Metal Ions Binding Site of Rat Lens αB-Crystallin". Thesis, 2014. http://ndltd.ncl.edu.tw/handle/fwjydk.

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博士<br>國立成功大學<br>化學系<br>102<br>The lens αB-crystallin, playing a major role in maintaining the transparency of the eye lens, possesses chaperone-like function to prevent the lens proteins from aggregation due to foreign stress and/or aging. In nonlenticular cells, it is involved in various neurological diseases, diabetes, and cancer. The role of some metal ions in the αB-crystallin biology has been reported. Theoretical calculations have proposed that the coordination site of human αB-crystallin for binding divalent metal ions were His101, His119, Lys121, His18 and Glu99. In this study, H18G, H
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Santos, Ariana Coelho Ferreira dos. "The solid products of L−arginine and divalent metal ions – synthesis, physicochemical characterization and biological properties." Master's thesis, 2020. http://hdl.handle.net/10316/93928.

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Dissertação de Mestrado em Química Medicinal apresentada à Faculdade de Ciências e Tecnologia<br>Dois dos grandes objetivos em Química Medicinal são sintetizar novos fármacos e aumentar a qualidade/potência dos que já se encontram comercialmente disponíveis, ao mesmo tempo que se pretende diminuir os efeitos secundários. Visto que, ao longo dos anos, os compostos de coordenação têm mostrado, de forma geral, propriedades biológicas bastante melhoradas em relação à molécula livre de origem, o trabalho apresentado na presente dissertação focou-se na síntese desses mesmos compostos.Neste sentido,
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26

Latwesen, David Gary. "Spectroscoptic characterization of the first coordination sphere of divalent metal ions at the active sites of enzymes." 1992. http://catalog.hathitrust.org/api/volumes/oclc/28161086.html.

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27

Chih-Yuan and 王志元. "Effect of home bleaching treatment on metal ions release from stainless steel orthodontic brackets." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/42875691061941695881.

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碩士<br>中山醫學大學<br>口腔材料科學研究所<br>95<br>This study was to evaluate the effect of home bleaching treatment on metal ions release from stainless steel orthodontic brackets, including 3M Unitek, Dentaurum, and Tomy. Six different bleaching treatments were used in this study. The amounts of iron, chromium, and nickel ions release from brackets were detected by inductively coupled plasma mass spectrometry. A scanning electron microscope and an atomic force microscopy were used to analyze the surface morphology and roughness, respectively. Results showed that the bleaching treatment and the bracket brand
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28

蘇偉廷. "The effects of divalent metal ions on oxidoreduction and nitroreduction of the NAD(P)H:flavin oxidoreductase (HP0642) from Helicobacter pylori." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/02372507332326871744.

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碩士<br>國立清華大學<br>生物科技研究所<br>100<br>In the previous study, the recombinant HP0642 protein which obtained from gene expression in E. coli SG13009 system has two majority functions as NAD(P)H electron donor dependent NAD(P)H-flavin oxidoreductase and the same electron donor dependent nitroreductase. In the previous study, it was found that the oxidoreductase activity of recHP0642 was inhibited by 1 mM Zn2+ or Hg2+ when NADH as electron donor. And the nitroreductase activity of recHP0642 was inhibited by 5 mM Zn2+ and Fe2+ when NADPH as electron donor. But the Cu2+ could make the nitroreductase
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29

Santoso, Shella Permatasari, and 黎美清. "Complex Formation of 2,3-Dihydroxybenzoic Acid and N-Acetylcysteine with Divalent Metal Ions: Solution Equilibrium, Synthesis, Characterization and Biological Activity Studies." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/15565797628335710536.

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博士<br>國立臺灣科技大學<br>化學工程系<br>104<br>Solution equilibriums of 2,3-dihydroxybenzoic acid, N-acetylcysteine and divalent transition metal ions (Mn2+, Co2+, Ni2+, Zn2+, Cu2+) were investigated in this study. The equilibrium constant values of binary and ternary compounds were determined by using potentiometric method at conditions similar to that of human physiology (37°C, ionic strength = 0.15 mol•dm-3 NaCl). The refinement of potentiometric data were done by using the Hyperquad 2008 computer program. The determination of equilibrium constants was confirmed by spectrophotometric method with refinem
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30

Cuzic-Feltens, Simona [Verfasser]. "Investigation of the catalytic mechanism of RNase P : the role of divalent metal ions and functional groups important for catalysis / vorgelegt von Simona Cuzic-Feltens." 2006. http://d-nb.info/979656133/34.

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31

Doyle, Colleen. "A Refined Method for Quantitation of Divalent Metal Ions in Metalloproteins and Local Stability and Conformational Heterogeneity of Amyotrophic Lateral Sclerosis-Associated Cu, Zn Superoxide Dismutase." Thesis, 2014. http://hdl.handle.net/10012/8440.

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Amyotrophic lateral sclerosis (ALS) is a devastating and progressive disease that results in selective death of motor neurons in the cortex, brain stem and spinal cord. ALS is the most common adult onset motor neuron disease resulting in paralysis and death, commonly within 2 – 5 years of symptom onset, yet there remains no effective treatment for the disease. The majority of ALS cases show no hereditary link (referred to as sporadic ALS or sALS); however, ~10% of cases show a dominant pattern of inheritance (referred to as familial ALS or fALS). Over 170 different mutations in human Cu, Zn su
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32

Dearden, David Vernell. "Experimental probes of gas phase ions and molecules: I. Product kinetic energy release measurements as a probe of reaction thermochemistry, dynamics, and chemical structure in systems containing transition metal ions. II. Photoelectron and optical studies of organic transient species." Thesis, 1989. https://thesis.library.caltech.edu/554/1/Dearden_dv_1989.pdf.

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The release of kinetic energy in the decomposition of a metastable ion is a reflection of both the overall energetics and the potential energy surface on which the process takes place. Chapter 1 applies measurements of the kinetic energy release distributions (KERDs) for decomposition of metastable Mn(CO)[x][+] to the dynamics and energetics of exchange processes for the CO ligands. All the dissociations can be described by statistical phase space theory, in agreement with efficient CO exchange rates indicating that conservation of electronic spin is not important to the dynamics. A general me
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Ιατρίδη, Ζαχαρούλα. "Μελέτη αποδέσμευσης ιόντων δισθενούς χαλκού από συμπολυμερή τύπου κτένας". Thesis, 2009. http://nemertes.lis.upatras.gr/jspui/handle/10889/2479.

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Διερευνήθηκε η δέσμευση/αποδέσμευση ιόντων Cu(II) ή/και αντίθετα φορτισμένων επιφανειοδραστικών ενώσεων από συμπολυμερή τύπου κτένας. Ο κεντρικός σκελετός ήταν το πολυ(ακρυλικό νάτριο), PANa, ενώ οι πλευρικές αλυσίδες ήταν το Πολυ(Ν,Ν-διμεθυλακρυλαμίδιο) και το πολυ(Ν-Ισοπροπυλακρυλαμίδιο). Η συμπλοκοποίηση των συμπολυμερών με τα ιόντα Cu(II)σε υδατικό περιβάλλον διερευνήθηκε με θολομετρία, ιξωδομετρία, φασματοφωτομετρία UV-Vis, δυναμική σκέδαση φωτός, ιχνηθέτηση με φθορίζοντες ιχνηθέτες και προσδιορισμό του ζ-δυναμικού. Σε επόμενο στάδιο διερευνήθηκε η δυνατότητα σχηματισμού τριμερών συμπλόκω
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Duarte, Claudia Berta. "Biocompatibilidade das principais ligas metálicas utilizadas em medicina dentária em Portugal." Master's thesis, 2017. http://hdl.handle.net/10284/6140.

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As ligas metálicas utilizadas em medicina dentária podem influenciar não apenas a qualidade e durabilidade das próteses e implantes dentários como também a saúde dos tecidos orais e até sistémicos. Antigamente os efeitos biológicos das ligas metálicas e materiais dentários eram ignorados em estudos e totalmente desconhecidos, porém com o passar do tempo observou-se a influência direta e indireta da biocompatibilidade destes metais e ligas metálicas no sucesso dos tratamentos dentários de reabilitação. O objetivo deste estudo é apresentar conteúdos atualizados e conceitos já conhecidos e comp
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