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1

Murata, Daisuke, Kenta Arai, Miho Iijima, and Hiromi Sesaki. "Mitochondrial division, fusion and degradation." Journal of Biochemistry 167, no. 3 (2019): 233–41. http://dx.doi.org/10.1093/jb/mvz106.

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Abstract The mitochondrion is an essential organelle for a wide range of cellular processes, including energy production, metabolism, signal transduction and cell death. To execute these functions, mitochondria regulate their size, number, morphology and distribution in cells via mitochondrial division and fusion. In addition, mitochondrial division and fusion control the autophagic degradation of dysfunctional mitochondria to maintain a healthy population. Defects in these dynamic membrane processes are linked to many human diseases that include metabolic syndrome, myopathy and neurodegenerat
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2

Fradin, Frank. "Up Close: Materials Science at Argonne National Laboratory." MRS Bulletin 11, no. 5 (1986): 34–35. http://dx.doi.org/10.1557/s0883769400054488.

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Basic and applied materials research at Argonne National Laboratory (ANL) is conducted by the Materials Science Division (MSD) and the Materials and Components Technology Division (MCT). Of the $30 million annual budget, $23 million comes from the U.S. Department of Energy (DOE) that funds Basic Energy Sciences (BES)-Materials Sciences, Reactor Development, Fusion Energy, Fossil Energy, and Conservation Technology. Another $5 million of the $30 million budget comes from the Nuclear Regulatory Commission and the remaining $2 million is from the Department of Defense.Representative projects in f
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Laitrakun, Seksan. "Decision fusion for composite hypothesis testing in wireless sensor networks over a shared and noisy collision channel." International Journal of Distributed Sensor Networks 16, no. 7 (2020): 155014772094020. http://dx.doi.org/10.1177/1550147720940204.

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We consider the composite hypothesis testing problem of time-bandwidth-constrained distributed detection. In this scenario, the probability distribution of the observed signal when the event of interest is happening is unknown. In addition, local decisions are censored and only those uncensored local decisions will be sent to the fusion center over a shared and noisy collision channel. The fusion center also has a limited time duration to collect transmitted decisions and make a final decision. Two types of medium access control that the sensor nodes apply to send their decisions are investiga
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Sha, Chao, Tian-cheng Shen, Jin-yu Chen, Yao Zhang, and Ru-chuan Wang. "Energy-Balanced Uneven Clustering Protocol Based on Regional Division for Sensor Networks." International Journal of Distributed Sensor Networks 2015 (2015): 1–11. http://dx.doi.org/10.1155/2015/647570.

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In view of the unbalanced energy consumption of traditional cluster-based sensor networks, this paper proposes a type of uneven clustering protocol in data collection. The network is divided into inner and outer regions according to the distance between nodes and the base station. The inner region is consisted of several layers and nodes in outer region are deployed in grids of different sizes. Sensor data is collected by nodes in outer region and then is be transmitted to the inner region. Nodes in the inner region do data fusion and forward data from the lower layer to the higher one. Simula
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Tarassenko, G. B. "ALTERNATIVE ENERGY SOURCES THEORY, PRACTICE, EXPERIMENT." Globus 7, no. 3(60) (2021): 4–12. http://dx.doi.org/10.52013/2658-5197-60-3-1.

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The paper attempts a comprehensive analysis and interpretation of the energy device based on the principles of «cold» nuclear fusion. It should be noted that the understanding of «cold» nuclear synthesis may include hightemperature reactions occurring in locally small volumes (for example, cavitation). In this case, the working fluid remains relatively «cold». Some devices, such as, «vortex heat engine» is already used for heat production. However, there are discussions about the excess heat compared to the energy expended (electric, chemical, etc.). Do not confuse this type of device with hea
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Sasaki, Darryl Y., and Mark J. Stevens. "Stacked, Folded, and Bent Lipid Membranes." MRS Bulletin 31, no. 7 (2006): 521–26. http://dx.doi.org/10.1557/mrs2006.136.

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Lipid membranes are generally thought of as flat or spherical structures, much as we would view the plasma membrane of a cell. Within the cell, however, there exists a wide variety of stacked, folded, and other forms of bent structures that support and enable such functions as photosynthesis, light-sensing, protein synthesis, molecular shuttling, chemical uptake and release, and cell division. These functions benefit from the high asymmetry of the membrane. Stacked or folded structures provide a highly concentrated and ordered assembly for facile energy and molecular transport, while bent stru
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Abarzhi, Snezhana I., and Walter Gekelman. "Preface: Non-equilibrium transport, interfaces, and mixing in plasmas." Physics of Plasmas 29, no. 3 (2022): 032103. http://dx.doi.org/10.1063/5.0088600.

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Non-equilibrium transport, interfaces, and interfacial mixing play an important role in plasmas in high and low energy density regimes, at astrophysical and at atomic scales, and in nature and technology. Examples include the instabilities and interfacial mixing in supernovae and in inertial confinement fusion, the particle-field interactions in magnetic fusion and in imploding Z-pinches, the downdrafts in stellar interiors and in the planetary magneto-convection, magnetic flux ropes and structures in the solar corona, and plasma thrusters and nano-fabrication. This Special Topic exposes the s
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8

Elsaka, Omar. "Mitochondrial dysfunction in cardiovascular disease: investigating therapeutic approaches to enhance patient outcomes." MGM Journal of Medical Sciences 12, no. 1 (2025): 127–35. https://doi.org/10.4103/mgmj.mgmj_383_24.

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Abstract Mitochondria, the energy-generating organelles, undergo continuous biosynthesis, fission, fusion, and degradation cycles to maintain structural integrity. While mitochondria in the adult heart are relatively static, their structural modifications, governed by mitochondrial morphology, are crucial for energy production, organelle shape, and stress adaptation. Mitochondrial fusion is mediated by proteins such as Mitofusin 1 (Mfn1), Mitofusin 2 (Mfn2), and Optic Atrophy 1 (Opa1), which interact with the endoplasmic reticulum, enhance mitophagy, remodel cristae, and regulate apoptosis. In
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9

Sanders, S. J., B. B. Back, R. V. F. Janssens, et al. "Additional evidence for fusion-fission inS32+24Mg reactions: Division of excitation energy and spin in the fission fragments." Physical Review C 41, no. 5 (1990): R1901—R1905. http://dx.doi.org/10.1103/physrevc.41.r1901.

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10

Xiao, Ling, Ruofan An, and Xue Zhang. "A Deep Learning Approach Based on Novel Multi-Feature Fusion for Power Load Prediction." Processes 12, no. 4 (2024): 793. http://dx.doi.org/10.3390/pr12040793.

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Adequate power load data are the basis for establishing an efficient and accurate forecasting model, which plays a crucial role in ensuring the reliable operation and effective management of a power system. However, the large-scale integration of renewable energy into the power grid has led to instabilities in power systems, and the load characteristics tend to be complex and diversified. Aiming at this problem, this paper proposes a short-term power load transfer forecasting method. To fully exploit the complex features present in the data, an online feature-extraction-based deep learning mod
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Wu, Weimin, Xiongfei Liu, Wanjun Yan, and Wenqiang Du. "A multilevel study on the variation characteristics of tip wake to wind turbines with different fusion tip structures." Transactions on Engineering and Technology Research 3 (September 13, 2024): 1–11. http://dx.doi.org/10.62051/7bjrk343.

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Based on the regional division and spatial discretization strategy of the established effective computational fluid dynamics (CFD) numerical model for the wake of an original tip wind turbine blade, a corresponding high-precision CFD calculation model is developed for a series of blade tip wind turbines with different fused tip structures. Transient numerical calculation results are obtained for each base sample matrix corresponding to different geometric parameters of the blade tip. The multi-level proper orthogonal decomposition (POD) mode spatial distribution characteristics of the blade ti
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Tokuyama, Takeshi, and Shigeru Yanagi. "Role of Mitochondrial Dynamics in Heart Diseases." Genes 14, no. 10 (2023): 1876. http://dx.doi.org/10.3390/genes14101876.

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Mitochondrial dynamics, including fission and fusion processes, are essential for heart health. Mitochondria, the powerhouses of cells, maintain their integrity through continuous cycles of biogenesis, fission, fusion, and degradation. Mitochondria are relatively immobile in the adult heart, but their morphological changes due to mitochondrial morphology factors are critical for cellular functions such as energy production, organelle integrity, and stress response. Mitochondrial fusion proteins, particularly Mfn1/2 and Opa1, play multiple roles beyond their pro-fusion effects, such as endoplas
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Kabra, Uma D., and Martin Jastroch. "Mitochondrial Dynamics and Insulin Secretion." International Journal of Molecular Sciences 24, no. 18 (2023): 13782. http://dx.doi.org/10.3390/ijms241813782.

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Mitochondria are involved in the regulation of cellular energy metabolism, calcium homeostasis, and apoptosis. For mitochondrial quality control, dynamic processes, such as mitochondrial fission and fusion, are necessary to maintain shape and function. Disturbances of mitochondrial dynamics lead to dysfunctional mitochondria, which contribute to the development and progression of numerous diseases, including Type 2 Diabetes (T2D). Compelling evidence has been put forward that mitochondrial dynamics play a significant role in the metabolism-secretion coupling of pancreatic β cells. The disrupti
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14

Yang, Jie, Weiqi Jin, Su Qiu, Fuduo Xue, and Meishu Wang. "Residual Interpolation Integrated Pixel-by-Pixel Adaptive Iterative Process for Division of Focal Plane Polarimeters." Sensors 22, no. 4 (2022): 1529. http://dx.doi.org/10.3390/s22041529.

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Residual interpolations are effective methods to reduce the instantaneous field-of-view error of division of focal plane (DoFP) polarimeters. However, their guide-image selection strategies are improper, and do not consider the DoFP polarimeters’ spatial sampling modes. Thus, we propose a residual interpolation method with a new guide-image selection strategy based on the spatial layout of the pixeled polarizer array to improve the sampling rate of the guide image. The interpolation performance is also improved by the proposed pixel-by-pixel, adaptive iterative process and the weighted average
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15

Knorre, Dmitry A., Konstantin Y. Popadin, Svyatoslav S. Sokolov, and Fedor F. Severin. "Roles of Mitochondrial Dynamics under Stressful and Normal Conditions in Yeast Cells." Oxidative Medicine and Cellular Longevity 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/139491.

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Eukaryotic cells contain dynamic mitochondrial filaments: they fuse and divide. Here we summarize data on the protein machinery driving mitochondrial dynamics in yeast and also discuss the factors that affect the fusion-fission balance. Fission is a general stress response of cells, and in the case of yeast this response appears to be prosurvival. At the same time, even under normal conditions yeast mitochondria undergo continuous cycles of fusion and fission. This seems to be a futile cycle and also expensive from the energy point of view. Why does it exist? Benefits might be the same as in t
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Nah, Jihoon, Shigeki Miyamoto, and Junichi Sadoshima. "Mitophagy as a Protective Mechanism against Myocardial Stress." Comprehensive Physiology 7, no. 4 (2017): 1407–24. https://doi.org/10.1002/j.2040-4603.2017.tb00786.x.

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ABSTRACTMitochondria are dynamic organelles that can undergo fusion, fission, biogenesis, and autophagic elimination to maintain mitochondrial quality control. Since the heart is in constant need of high amounts of energy, mitochondria, as a central energy supply source, play a crucial role in maintaining optimal cardiac performance. Therefore, it is reasonable to assume that mitochondrial dysfunction is associated with the pathophysiology of heart diseases. In non‐dividing, post‐mitotic cells such as cardiomyocytes, elimination of dysfunctional organelles is essential to maintaining cellular
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17

Marchetti, M. A., C. Tschudi, H. Kwon, S. L. Wolin, and E. Ullu. "Import of proteins into the trypanosome nucleus and their distribution at karyokinesis." Journal of Cell Science 113, no. 5 (2000): 899–906. http://dx.doi.org/10.1242/jcs.113.5.899.

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In all eukaryotic organisms proteins are targeted to the nucleus via a receptor-mediated mechanism that requires a specific nuclear localization sequence (NLS) in the protein. Little is known about this process in trypanosomatid protozoa that are considered amongst the earliest divergent eukaryotes. We have used the green fluorescent protein (gfp) and beta-galactosidase reporters to identify the NLS of two trypanosomal proteins, namely the Trypanosoma brucei La protein homologue and histone H2B of T. cruzi. A monopartite NLS was demonstrated at the C terminus of the La protein, whereas a bipar
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18

Tesarik, Jan, and Raquel Mendoza-Tesarik. "Mitochondria in Human Fertility and Infertility." International Journal of Molecular Sciences 24, no. 10 (2023): 8950. http://dx.doi.org/10.3390/ijms24108950.

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In human spermatozoa and oocytes (and their surrounding granulosa cells), mitochondria carry out important functions relating to human fertility and infertility. Sperm mitochondria are not transmitted to the future embryo, but are closely related to the generation of energy needed for sperm movement, capacitation, and acrosome reactions, as well as for sperm–oocyte fusion. On the other hand, oocyte mitochondria produce energy required for oocyte meiotic division and their abnormalities can thus cause oocyte and embryo aneuploidy. In addition, they play a role in oocyte calcium metabolism and i
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Harbauer, Angelika B., Magdalena Opalińska, Carolin Gerbeth, et al. "Cell cycle–dependent regulation of mitochondrial preprotein translocase." Science 346, no. 6213 (2014): 1109–13. http://dx.doi.org/10.1126/science.1261253.

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Mitochondria play central roles in cellular energy conversion, metabolism, and apoptosis. Mitochondria import more than 1000 different proteins from the cytosol. It is unknown if the mitochondrial protein import machinery is connected to the cell division cycle. We found that the cyclin-dependent kinase Cdk1 stimulated assembly of the main mitochondrial entry gate, the translocase of the outer membrane (TOM), in mitosis. The molecular mechanism involved phosphorylation of the cytosolic precursor of Tom6 by cyclin Clb3-activated Cdk1, leading to enhanced import of Tom6 into mitochondria. Tom6 p
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20

Fang, Yu, Dongbo Liu, Sixian Zhao, and Daishen Deng. "Improving OSAHS Prevention Based on Multidimensional Feature Analysis of Snoring." Electronics 12, no. 19 (2023): 4148. http://dx.doi.org/10.3390/electronics12194148.

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Obstructive Sleep Apnea–Hypopnea Syndrome (OSAHS), a severe respiratory sleep disorder, presents a significant threat to human health and even endangers life. As snoring is the most noticeable symptom of OSAHS, identifying OSAHS via snoring sound analysis is vital. This study aims to analyze the time-domain and frequency-domain characteristics of snoring sounds to detect OSAHS and its severity. The snoring sounds are extracted and scrutinized from nighttime acoustic signals, with spectral energy ratio features being applied, calculated via the snore detection frequency division method. A varie
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Liu, Dong, Youchun Pi, Zhengyang Tang, Hongpeng Hua, and Xiaopeng Wang. "A Fusion Model for Predicting the Vibration Trends of Hydropower Units." Energies 17, no. 23 (2024): 5847. http://dx.doi.org/10.3390/en17235847.

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Hydropower units are essential to the safe, stable, and efficient operation of modern power systems, particularly given the current expansion of renewable energy systems. To enable timely monitoring of unit performance, it is critical to investigate the trends in vibration signals, to enhance the accuracy and reliability of vibration trend prediction models. This paper proposes a fusion model for the vibration signal trend prediction of hydropower units based on the waveform extension method empirical mode decomposition (W-EMD) and long short-term memory neural network (LSTMNN). The fusion mod
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Dasgupta, Asish, Danchen Wu, Lian Tian, et al. "Mitochondria in the Pulmonary Vasculature in Health and Disease: Oxygen‐Sensing, Metabolism, and Dynamics." Comprehensive Physiology 10, no. 2 (2020): 713–65. https://doi.org/10.1002/j.2040-4603.2020.tb00125.x.

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AbstractIn lung vascular cells, mitochondria serve a canonical metabolic role, governing energy homeostasis. In addition, mitochondria exist in dynamic networks, which serve noncanonical functions, including regulation of redox signaling, cell cycle, apoptosis, and mitochondrial quality control. Mitochondria in pulmonary artery smooth muscle cells (PASMC) are oxygen sensors and initiate hypoxic pulmonary vasoconstriction. Acquired dysfunction of mitochondrial metabolism and dynamics contribute to a cancer‐like phenotype in pulmonary arterial hypertension (PAH). Acquired mitochondrial abnormali
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Rahman, Wazir Ur, Qiao Gang, Feng Zhou, et al. "Energy-Efficient MAC Protocol for Underwater Sensor Networks Using CSMA/CA, TDMA, and Actor–Critic Reinforcement Learning (AC-RL) Fusion." Acoustics 7, no. 3 (2025): 39. https://doi.org/10.3390/acoustics7030039.

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Due to the dynamic and harsh underwater environment, which involves a long propagation delay, high bit error rate, and limited bandwidth, it is challenging to achieve reliable communication in underwater wireless sensor networks (UWSNs) and network support applications, like environmental monitoring and natural disaster prediction, which require energy efficiency and low latency. To tackle these challenges, we introduce AC-RL-based power control (ACRLPC), a novel hybrid MAC protocol that can efficiently integrate Carrier Sense Multiple Access with Collision Avoidance (CSMA/CA)-based MAC and Ti
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Hoepker, Alexander C., Ariel Wang, Alix Le Marois, Klaus Suhling, Yuling Yan, and Gerard Marriott. "Genetically encoded sensors of protein hydrodynamics and molecular proximity." Proceedings of the National Academy of Sciences 112, no. 20 (2015): E2569—E2574. http://dx.doi.org/10.1073/pnas.1424021112.

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The specialized light organ of the ponyfish supports the growth of the bioluminescent symbiont Photobacterium leiognathi. The bioluminescence of P. leiognathi is generated within a heteromeric protein complex composed of the bacterial luciferase and a 20-kDa lumazine binding protein (LUMP), which serves as a Förster resonance energy transfer (FRET) acceptor protein, emitting a cyan-colored fluorescence with an unusually long excited state lifetime of 13.6 ns. The long fluorescence lifetime and small mass of LUMP are exploited for the design of highly optimized encoded sensors for quantitative
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Natyaganova, A. V., E. V. Mincheva, and Yu S. Bukin. "Cytomorphology of the wound healing process in the green filamentous algae, Ulothrix zonata (F. Weber & Mohr) K tzing 1833." Limnology and Freshwater Biology, no. 2 (2022): 1229–43. http://dx.doi.org/10.31951/2658-3518-2022-a-2-1229.

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Abstract. For the first time, we present a cytomorphological description of the self-healing (repair) process of damaged thalli sites, wound healing , in the green filamentous algae, Ulothrix zonata (F. Weber & Mohr) K tzing 1833. In the filaments of this species from Lake Baikal and the Angara (Baikal outflow), Zhilishche (Baikal inflow) and Ida (Angara inflow) rivers, light microscopy methods revealed dome-like and conical protrusions and elongations of transverse cell walls directed into adjacent dead (without protoplast) and defective (with deformed chloroplasts) cells. At the same tim
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Gul, Noor, Su Min Kim, Jehad Ali, and Junsu Kim. "UAV aided virtual cooperative spectrum sensing for cognitive radio networks." PLOS ONE 18, no. 9 (2023): e0291077. http://dx.doi.org/10.1371/journal.pone.0291077.

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Cooperative spectrum sensing (CSS) involves multiple secondary users (SUs) reporting primary user (PU) channel sensing states to the fusion center (FC). However, the high overheads associated with multi-user CSS impose power limitations that limit its usefulness in unmanned aerial vehicle (UAV) networks. To address this challenge, we propose a virtual CSS, where a single UAV conducts CSS while following a circular flight trajectory in the air. The novelty of our approach is presenting a working frame structure for the UAV flight, including sensing and data transmission periods with further div
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Wang, Jingjing, Jie Shen, Wei Shi, Gang Qiao, Shaoen Wu, and Xinjie Wang. "A Novel Energy-Efficient Contention-Based MAC Protocol Used for OA-UWSN." Sensors 19, no. 1 (2019): 183. http://dx.doi.org/10.3390/s19010183.

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A hybrid optical-acoustic underwater wireless sensor network (OA-UWSN) was proposed to solve the problem of high-speed transmission of real-time video and images in marine information detection. This paper proposes a novel energy-efficient contention-based media access control (MAC) protocol (OA-CMAC) for the OA-UWSN. Based on optical-acoustic fusion technology, our proposed OA-CMAC combines the postponed access mechanism in carrier sense multiple access with collision avoidance (CSMA/CA) and multiplexing-based spatial division multiple access (SDMA) technology to achieve high-speed and real-t
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Han, Weimin, Shijun Li, and Weidong Li. "Study of Wireless Sensor Network Location Algorithm and Data Collection Protocol." International Journal of Online Engineering (iJOE) 12, no. 10 (2016): 70. http://dx.doi.org/10.3991/ijoe.v12i10.6209.

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<p style="margin: 0in 0in 10pt;"><span style="font-size: small;"><span style="font-family: Times New Roman;"><span style="-ms-layout-grid-mode: line;">It is deduced that the network life time is inversely proportional to the zone area of the collection data that each sink is responsible for. That is to say, when the zone area in the charge of a sink is smaller, the average load of nodes distributed in this area and the energy consumption are smaller, while the network life time is longer. MSGP protocol is proposed, with several round cluster head candidate zones, fixed
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Gryś, Sławomir, and Waldemar Minkina. "Noninvasive Methods of Active Thermographic Investigation: Short Overview of Theoretical Foundations with an Example of Application." Energies 15, no. 13 (2022): 4865. http://dx.doi.org/10.3390/en15134865.

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The field of non-destructive testing using thermography (NDT—Non-Destructive Testing and NDE—Non Destructive Evaluation) was established in the 1960s as a competitive and complementary method to ultrasonic or X-ray testing. Non-destructive quality control of objects is essential in modern industry, especially in mass production. It is an integral part of the quality control process. The reason for the introduction of non-destructive testing into diagnostic techniques were disasters and failures of various equipment and structures. Over the years, a division has been drawn between passive and a
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Li, Tianxin, Yuxin Duan, Shanbo Guo, Linglong Meng, and Matomela Nametso. "Study on Applicability of Distributed Hydrological Model under Different Terrain Conditions." Sustainability 12, no. 22 (2020): 9684. http://dx.doi.org/10.3390/su12229684.

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This research aimed to study the applicability and limitations of a distributed hydrological model under discontinuous steep topography and hydrogeological conditions. Based on GIS spatial analysis, typical cases of steep and gentle terrains were selected to construct the distributed hydrological model framework of the research areas (Qinhuangdao and Zhuanghe City, China). The observed runoff was used to test the applicability of the model in different terrain watersheds and to analyze the versatility of the model structure and the relevant parameters of the core modules. The results show that
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Hoffmann, Lena, Marco B. Rust, and Carsten Culmsee. "Actin(g) on mitochondria – a role for cofilin1 in neuronal cell death pathways." Biological Chemistry 400, no. 9 (2019): 1089–97. http://dx.doi.org/10.1515/hsz-2019-0120.

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AbstractActin dynamics, the coordinated assembly and disassembly of actin filaments (F-actin), are essential for fundamental cellular processes, including cell shaping and motility, cell division or organelle transport. Recent studies highlighted a novel role for actin dynamics in the regulation of mitochondrial morphology and function, for example, through mitochondrial recruitment of dynamin-related protein 1 (Drp1), a key factor in the mitochondrial fission machinery. Mitochondria are dynamic organelles, and permanent fission and fusion is essential to maintain their function in energy meta
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Wang, Jingxuan, Lizhi Dai, Tong Yu, and Jianhua Xiao. "Insights into the progressive impact of high-fat-diet induced insulin resistance on skeletal muscle and myocardium: A comprehensive study on C57BL6 mice." PLOS ONE 20, no. 1 (2025): e0310458. https://doi.org/10.1371/journal.pone.0310458.

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This study aims to provide a theoretical foundation for the future management of diabetes at various stages induced by a high-fat diet. Specifically, it seeks to determine the appropriate pharmacological interventions for each phase of diabetes development and the targeted therapeutic directions at different stages of diabetes progression. This investigation employed C57BL6 mice as experimental subjects, successfully establishing an insulin resistance model through a 12-week high-fat diet. Clinical manifestations, weight, body composition, and overall health of each mouse group were observed o
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Douiev, Liza, Ruth Sheffer, Gabriella Horvath, and Ann Saada. "Bezafibrate Improves Mitochondrial Fission and Function in DNM1L-Deficient Patient Cells." Cells 9, no. 2 (2020): 301. http://dx.doi.org/10.3390/cells9020301.

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Mitochondria are involved in many cellular processes and their main role is cellular energy production. They constantly undergo fission and fusion, and these counteracting processes are under strict balance. The cytosolic dynamin-related protein 1, Drp1, or dynamin-1-like protein (DNM1L) mediates mitochondrial and peroxisomal division. Defects in the DNM1L gene result in a complex neurodevelopmental disorder with heterogeneous symptoms affecting multiple organ systems. Currently there is no curative treatment available for this condition. We have previously described a patient with a de novo h
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Shoieb, D., and S. Youssef. "Neurological Disorder Detection of Brain Abnormal Activities Using a New Enhanced Computer-aided Model." Journal of Physics: Conference Series 2128, no. 1 (2021): 012017. http://dx.doi.org/10.1088/1742-6596/2128/1/012017.

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Abstract In the field of neurodevelopmental disorders, Autism Spectrum Disorders (ASD) are recognized as one of the dramatically increased etiologically and clinically heterogeneous diseases. Although, increasing the number of children who have difficulties in communication or suffer from sudden malfunction of the brain, the current diagnostic approaches for those kind of disease are time-consuming and are mainly based on clinical interviews. In this paper, a new enhanced diagnostic model is introduced addressing many of the challenges which threats the analysis of Electroencephalography (EEG)
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Liu, Bo, Suoliang Chang, Sheng Zhang, et al. "Seismic-Geological Integrated Study on Sedimentary Evolution and Peat Accumulation Regularity of the Shanxi Formation in Xinjing Mining Area, Qinshui Basin." Energies 15, no. 5 (2022): 1851. http://dx.doi.org/10.3390/en15051851.

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Accurate identification of the lithofacies and sedimentary facies of coal-bearing series is significant in the study of peat accumulation, coal thickness variation and coal-measured unconventional gas. This research integrated core, logging and 3D seismic data to conduct a comprehensive seismic–geological study on the sedimentary evolution characteristics and peat accumulation regularity of the Shanxi Formation in the Xinjing mining area of the Qinshui Basin. Firstly, the high-resolution sequence interface was identified, and the isochronous stratigraphic framework of the coal-bearing series w
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Rolison, Debra R., Jeffery W. Long, and Joseph F. Parker. "(Battery Division Technology Award) Dendrite-Free Architected Zinc Anodes: Enabling Sustainable, Safe, Scalable, Rechargeable, and Manufacturable Next-Generation Aqueous Batteries." ECS Meeting Abstracts MA2024-02, no. 7 (2024): 884. https://doi.org/10.1149/ma2024-027884mtgabs.

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Architected electrodes are a design concept in which the key transport functions of electrochemistry—electrons, ions, molecules—are wired in three-dimensions (3D) throughout the volume of an ultraporous, high surface-area scaffold [1–3]. Our focus on nonperiodic architectural variants such as foams and sponges and our ability to 3D-wire elementary transport and reaction processes at nanoscopic, mesoscopic, and macroscopic levels transforms how active materials and electrode architectures are designed for higher-performance electrochemical energy storage, particularly for applications with chal
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Chiba, Kazuhiro. "(Organic and Biological Electrochemistry Division Manuel M. Baizer Award, Digital Presentation) Electron-Transfer-Triggered Smart Reactions Boost a Better Anthropocene." ECS Meeting Abstracts MA2022-01, no. 42 (2022): 1827. http://dx.doi.org/10.1149/ma2022-01421827mtgabs.

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It is important that chemical reactions initiated by electron transfer associated with electrodes can be achieved by precise control of intramolecular and intermolecular electron transfer of organic compounds, which is difficult to achieve by general chemical methods. Expectations for a new production process that positively controls the electron transfer is also expanding dramatically. Here, the solvent that dissolves the substrate for reaction, the network structure of the ionic species in the solution, and the role of coexisting substances are exactly grasped, and the total energy consumpti
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38

Maurel, Alexis, Ana Cristina Martinez, Sylvie Grugeon, et al. "(Battery Division Postdoctoral Associate Research Award Sponsored by MTI Corporation and the Jiang Family Foundation) 3D Printing of Batteries: Fiction or Reality?" ECS Meeting Abstracts MA2022-02, no. 3 (2022): 214. http://dx.doi.org/10.1149/ma2022-023214mtgabs.

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Motivated by the request to build shape-conformable flexible, wearable and customizable batteries while maximizing the energy storage and electrochemical performances, additive manufacturing (AM) appears as a revolutionary discipline. Battery components such as electrodes, separator, electrolyte, current collectors and casing can be tailored with any shape, allowing the direct incorporation of batteries and all electronics within the final three-dimensional object. AM also paves the way toward the implementation of complex 3D electrode architectures that could enhance significantly the power b
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39

Bălășescu, Simona, Nicoleta Andreea Neacșu, Anca Madar, Alexandra Zamfirache, and Marius Bălășescu. "Research of the Smart City Concept in Romanian Cities." Sustainability 14, no. 16 (2022): 10004. http://dx.doi.org/10.3390/su141610004.

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The Smart City concept has emerged in the last decade as a fusion of ideas about how information and communication technologies could improve the functioning of cities. A new concept, that of a sustainable Smart City, is already under discussion. This article aims at analyzing the Smart City concept in Romania. The resulting advantages, but also the difficulties and obstacles that need to be confronted, are considered when becoming a Smart City. When a city wants to become smart, it must consider both the advantages and the difficulties it will face in this endeavor. This paper has been able t
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Wen, Yuliang, Shaobin Li, Fangfang Zhao, et al. "Changes in the Mitochondrial Dynamics and Functions Together with the mRNA/miRNA Network in the Heart Tissue Contribute to Hypoxia Adaptation in Tibetan Sheep." Animals 12, no. 5 (2022): 583. http://dx.doi.org/10.3390/ani12050583.

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This study aimed to provide insights into molecular regulation and mitochondrial functionality under hypoxia by exploring the mechanism of adaptation to hypoxia, blood indexes, tissue morphology, mRNA/miRNA regulation, mitochondrial dynamics, and functional changes in Tibetan sheep raised at different altitudes. With regard to blood indexes and myocardial morphology, the HGB, HCT, CK, CK-MB, LDH, LDH1, SOD, GPX, LDL level, and myocardial capillary density were significantly increased in the sheep at higher altitudes (p < 0.05). The RNA-seq results suggested the DEmRNAs and DEmiRNAs are main
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Wang, Libo, Xiangyin Zhang, Kaiyu Qin, Zhuwei Wang, Jiayi Zhou, and Deyu Song. "AoI Analysis of Satellite–UAV Synergy Real-Time Remote Sensing System." Remote Sensing 16, no. 17 (2024): 3305. http://dx.doi.org/10.3390/rs16173305.

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With the rapid development of space–air–ground integrated networks (SAGIN), the synergy between the satellite and unmanned aerial vehicles (UAVs) in sensing environmental status information reveals substantial potential. In SAGIN, applications such as disaster response and military operations require fresh status information to respond effectively. The freshness of information, quantified by the age of information (AoI) metric, is crucial for an effective response. Therefore, it is urgent to investigate the AoI in real-time remote sensing systems leveraging satellite–UAV synergy. To this end,
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42

Oganessian, Yu Ts. "Superheavy elements." Pure and Applied Chemistry 76, no. 9 (2004): 1715–34. http://dx.doi.org/10.1351/pac200476091715.

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One of the fundamental outcomes of nuclear theory is the predicted existence of increased stability in the region of unknown superheavy elements. This hypothesis, proposed more than 35 years ago and intensively developed during all this time, significantly extends the limits of existence of chemical elements. “Magic ”nuclei with closed proton and neutron shells possess maximum binding energy. For the heaviest nuclides, a considerable stability is predicted close to the deformed shells with Z = 108, N = 162. Even higher stability is expected for the neutron-rich nuclei close to the spherical sh
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43

Yang, Ping, Fang-Jing Li, Shi-Wen Huang, et al. "Physiological and Transcriptional Response of Xanthomonas oryzae pv. oryzae to Berberine, an Emerging Chemical Control." Phytopathology® 110, no. 5 (2020): 1027–38. http://dx.doi.org/10.1094/phyto-09-19-0327-r.

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Berberine, a botanical drug, has great ability to inhibit the growth of Xanthomonas oryzae pv. oryzae. However, the antibacterial mechanism of berberine against X. oryzae pv. oryzae remains poorly understood. In this study, we investigated the physiological and transcriptional response of X. oryzae pv. oryzae to berberine. When strain X. oryzae pv. oryzae GX13 was treated with berberine (10 µg/ml), the hypersensitive response in tobacco, virulence to rice, pathogen population in the rice xylem, production of extracellular polysaccharide (EPS), and activity of extracellular hydrolases decreased
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Hernandez, Monica N., and Steven E. Lindow. "Contact-dependent traits in Pseudomonas syringae B728a." PLOS ONE 16, no. 2 (2021): e0241655. http://dx.doi.org/10.1371/journal.pone.0241655.

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Production of the biosurfactant syringafactin by the plant pathogen Pseudomonas syringae B728a is a surface contact-dependent trait. Expression of syfA, as measured using a gfp reporter gene fusion was low in planktonic cells in liquid cultures but over 4-fold higher in cells immobilized on surfaces as varied as glass, plastic, paper, parafilm, agar, membrane filters, and leaves. Induction of syfA as measured by GFP fluorescence was rapid, occurring within two hours after immobilization of cells on surfaces. Comparison of the global transcriptome by RNA sequencing of planktonic cells in a nutr
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Pei, Shanshan, Mohammad Minhajuddin, Brett M. Stevens, et al. "Regulation of Mitochondrial Morphology Is Important for Leukemia Stem Cell Function." Blood 126, no. 23 (2015): 842. http://dx.doi.org/10.1182/blood.v126.23.842.842.

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Abstract Studies from normal cell biology have demonstrated that mitochondria can switch between fission-active and fusion-active states to dramatically change their morphology during important developmental events such as lineage differentiation and cell division. Further, very recent research has revealed intriguing interactions between mitochondrial morphology regulation and oncogenic signals in cancer. To date however, whether mitochondrial morphology regulation plays a role in cancer stem cell function remains largely unknown. We report, in acute myelogenous leukemia (AML), leukemia stem
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Vannoni, Alessandra, Pierdomenico Lorusso, Pietro Arena, et al. "STEAM Experimental Facility: A Step Forward for the Development of the EU DEMO BoP Water Coolant Technology." Energies 16, no. 23 (2023): 7811. http://dx.doi.org/10.3390/en16237811.

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Within the EUROfusion roadmap for the technological development of the European-DEMOnstration (EU-DEMO) reactor, a key point has been identified in the discontinuous operation (pulse-dwell-pulse) of the machine. Water Cooled Lithium Lead (WCLL) Breeding Blanket (BB) Primary Heat Transfer Systems (PHTSs) adopt technology and components commonly used in nuclear fission power plants, whose performances could be negatively affected by the above mentioned pulsation, as well as by low-load operation in the dwell phase. This makes mandatory a full assessment of the functional feasibility of such comp
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Cheng, Zhangliang, Kohei Kume, and Markus Müschen. "MYC to BCL6 State-Transitions Determine Cell Size and Metabolic Fluctuations and Define a Novel Biorhythm in B-Cell Malignancies." Blood 142, Supplement 1 (2023): 2769. http://dx.doi.org/10.1182/blood-2023-190972.

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Background: Cell size fluctuations are well-documented during critical transitions during normal B-cell development. For instance, during early stages of development, “large cycling pre-B cells” (also classified as Fraction C') eventually exit cell cycle and shrink to become “small resting pre-B cells” (Fraction D) to enable immunoglobulin light chain gene recombination. We and others had shown that this transition is marked by loss of Myc expression and gain of Bcl6. Later in development, germinal center B-cells cycle between large MYC+ “centroblast” and smaller BCL6+ “centrocyte” states betw
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Gong, Yuehong, Meichi Pan, Hang Ren, et al. "Roles of Mitochondrial Fusion and Division in Harmine Derivative H‐2‐168‐Induced Neurotoxicity." Journal of Immunology Research 2025, no. 1 (2025). https://doi.org/10.1155/jimr/6678026.

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Background: Harmine (HM) has several pharmacological effects; however, severe neurotoxicity limits its clinical application and development. HM neurotoxicity is associated with abnormal energy metabolism. This study aimed to explore the roles and underlying mechanisms of mitochondrial fusion and division in HM derivative H‐2‐168‐induced neurotoxicity.Methods: PC12 cells were treated with H‐2‐168, Mdivi‐1 (an inhibitor of mitochondrial division), or a combination of both. Cell viability, levels of reactive oxygen species (ROS), adenosine triphosphate (ATP), lactic dehydrogenase (LDH), mitochond
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Ongenae, Steven, Maxim Cuvelier, Jef Vangheel, Herman Ramon, and Bart Smeets. "Activity-Induced Fluidization and Arrested Coalescence in Fusion of Cellular Aggregates." Frontiers in Physics 9 (June 9, 2021). http://dx.doi.org/10.3389/fphy.2021.649821.

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At long time scales, tissue spheroids may flow or appear solid depending on their capacity to reorganize their internal structure. Understanding the relationship between intrinsic mechanical properties at the single cell level, and the tissue spheroids dynamics at the long-time scale is key for artificial tissue constructs, which are assembled from multiple tissue spheroids that over time fuse to form coherent structures. The dynamics of this fusion process are frequently analyzed in the framework of liquid theory, wherein the time scale of coalescence of two droplets is governed by its radius
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Labbé, Katherine, Shona Mookerjee, Maxence Le Vasseur, Eddy Gibbs, Chad Lerner, and Jodi Nunnari. "The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis." Journal of Cell Biology 220, no. 11 (2021). http://dx.doi.org/10.1083/jcb.202103122.

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Mitochondrial function is integrated with cellular status through the regulation of opposing mitochondrial fusion and division events. Here we uncover a link between mitochondrial dynamics and lipid metabolism by examining the cellular role of mitochondrial carrier homologue 2 (MTCH2). MTCH2 is a modified outer mitochondrial membrane carrier protein implicated in intrinsic cell death and in the in vivo regulation of fatty acid metabolism. Our data indicate that MTCH2 is a selective effector of starvation-induced mitochondrial hyperfusion, a cytoprotective response to nutrient deprivation. We f
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