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Journal articles on the topic 'DMEK'

Author: Grafiati

Published: 10 March 2023

Last updated: 26 July 2025

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1

Suk, S. A., S. Yu Mogilevskyy, M. I. Kovtun, and B. B. Zhupan. "A new method of assessing microcirculation of the central retina in patients with different stages of diabetic macular edema in type 2 diabetes." INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine) 21, no. 2 (2025): 167–73. https://doi.org/10.22141/2224-0721.21.2.2025.1515.

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Background. Diabetic macular edema (DME) can develop at any stage of diabetic retinopathy, regardless of its severity. One of the triggers believed to be responsible for the accumulation of fluid in the macular area is ischemia as a frequent and severe complication of diabetic retinopathy. Optical coherence tomography angiography is a non-invasive technique that allows for visualization of retinal vascular plexus layers, quantification of microvascular parameters and correlation with functional and morphological data. Research aimed at identifying early preclinical biomarkers of microvascular

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Oganesyan, Oganes G., A. A. Grdikanyan, S. S. Yakovleva, and V. R. Getadaryan. "THE PARTIAL DESCEMET'S STRIPPING WITH TRANSPLANTATION OF DESCEMET'S TRANSPLANT UNDER ENDOTHELIAL DYSTROPHY OF CORNEA." Medical Journal of the Russian Federation 23, no. 5 (2017): 248–53. http://dx.doi.org/10.18821/0869-2106-2017-23-5-248-253.

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The DMEK technique is applied five times more rarely than DS(A)EK despite that DMEK provides higher functional result. The main causes are technical "convolution" of implementation, long period of training, accompanied by prolonged operations, higher reject control of donor's tissue, increased rate of dependency of endothelium and mismatch of transplant. Therefore, an efficient technique is needed similar to DMEK though simpler than DMEK.The purpose of study. To analyze the results of implantation of Descemet's transplant (DMET) in patients with endothelium dystrophy of cornea (Fuchs) on the b

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Giebel, Arthur W. "DMEK." International Ophthalmology Clinics 53, no. 1 (2013): 1–14. http://dx.doi.org/10.1097/iio.0b013e31827744c4.

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Kammrath Betancor, Paola, Daniel Böhringer, Philip Maier, Thabo Lapp, and Thomas Reinhard. "Splenectomy as a Risk Factor for Graft Rejection Following Endothelial Transplantation: Retrospective Study." Interactive Journal of Medical Research 13 (September 10, 2024): e50106. http://dx.doi.org/10.2196/50106.

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Background Anterior chamber–associated immune deviation (ACAID) is an active immunotolerance mechanism, which is induced by placing antigen into the anterior eye chamber as long as a major surgical trauma is avoided. For this reason, ACAID may be a major contributor to the favorable immunologic outcomes in Descemet membrane endothelial keratoplasty (DMEK). Rodent models have demonstrated the importance of a functional spleen for the development of an ACAID. Objective This study aimed to investigate whether splenectomy leads to increased rejection rates after DMEK in humans. Methods A retrospec

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Morelli, Alberto, Rosangela Ferrandina, Eleonora Favuzza, Michela Cennamo, and Rita Mencucci. "3D Visualization System in Descemet Membrane Endothelial Keratoplasty (DMEK): A Six-Month Comparison with Conventional Microscope." Journal of Clinical Medicine 11, no. 15 (2022): 4312. http://dx.doi.org/10.3390/jcm11154312.

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Background: To compare the efficacy and safety of Descemet membrane endothelial keratoplasty (DMEK) surgery using the three-dimensional (3D) display system NGENUITY to DMEK surgery performed with the traditional microscope (TM) in patients affected by Fuchs Endothelial Corneal Disease (FECD). Methods: Retrospective comparative study of 40 pseudophakic eyes of 40 patients affected by FECD who underwent DMEK surgery. Twenty patients (3D group) were operated on using the 3D display system and 20 patients (TM group) were operated on using the traditional microscope. Best spectacle corrected visual

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Perez, AlfonsoVasquez, Mehran Zarei-Ghanavati, and Christopher Liu. "DMEK calling." Journal of Ophthalmic and Vision Research 11, no. 4 (2016): 343. http://dx.doi.org/10.4103/2008-322x.194067.

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Gorovoy, Mark S. "DMEK Complications." Cornea 33, no. 1 (2014): 101–4. http://dx.doi.org/10.1097/ico.0000000000000023.

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Semler-Collery, Axelle, Florian Bloch, George Hayek, Christophe Goetz, and Jean Marc Perone. "Comparison of triple-DMEK to pseudophakic-DMEK: A cohort study of 95 eyes." PLOS ONE 17, no. 5 (2022): e0267940. http://dx.doi.org/10.1371/journal.pone.0267940.

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Previous comparative studies show that triple Descemet membrane endothelial keratoplasty (DMEK) (i.e. phacoemulsification followed immediately by DMEK) has either equivalent or better visual outcomes than DMEK in pseudophakic patients. To resolve this discrepancy, a retrospective cohort study was conducted. All consecutive patients with Fuchs Endothelial Corneal Dystrophy who underwent triple or pseudophakic DMEK in 2015–2019 in a tertiary-care hospital (France) and were followed for >12 months were compared in terms of best spectacle-corrected visual acuity (BSCVA), final refractive outcom

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Oganesyan, Oganes G., P. V. Makarov, A. A. Grdikanyan, V. R. Getadaryan, and S. V. Milash. "THE PARTIAL TRANSPLANTATION OF DESCEMET’S MEMBRANE WITH ENDOTHELIUM (½ AND ¼ DMEK)." Medical Journal of the Russian Federation 24, no. 2 (2018): 78–82. http://dx.doi.org/10.18821/0869-2106-2018-24-2-78-82.

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The lamellar keratoplasty is the first operation of choice under selective pathology of cornea. In view of satisfactory results of endothelium surgery similar operations are implemented at more earlier stages that increases need in donor tissue. The life-span of population increases hence number of patients in need of cornea transplantation also increases and number of intact cadaver corneas decreases because of stable increasing of number of surgical interventions at the frontal section of eye. The purpose of study is to analyze operations of partial transplantation of Descemet's membrane wit

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Herskowitz, William R., Christopher W. Seery, Matthew Camacho, Sander Dubovy, and Ellen H. Koo. "Descemet Membrane Endothelial Keratoplasty for Late Corneal Edema Secondary to Obstetrical Forceps–Related Tears." Cornea Open 3, no. 3 (2024): e0040. http://dx.doi.org/10.1097/coa.0000000000000040.

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Purpose: The purpose of our paper is to describe the outcome of Descemet membrane endothelial keratoplasty (DMEK) in patients with a history of known obstetrical forceps–related tears who developed clinically significant corneal edema in their eighth decade of life. Methods: Case series. Results: Two patients with a known history of obstetrical forceps–related tears presented with corneal edema and vertical tears of Descemet membrane consistent with birth trauma. DMEK was performed for both cases. Case 1 underwent pseudophakic DMEK, and Case 2 underwent combined phacoemulsification and DMEK (t

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Parekh, Mohit, Alexander George Wallace, Matteo Airaldi, et al. "Performance outcomes from a DMEK peeling and preparation wet lab." BMJ Open Ophthalmology 9, no. 1 (2024): e001540. http://dx.doi.org/10.1136/bmjophth-2023-001540.

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ObjectiveTo evaluate the Descemet membrane endothelial keratoplasty (DMEK) preparation performance of trainee surgeons in an ex vivo human donor cornea DMEK wet lab simulation setting.MethodsHuman donor corneoscleral rims unsuitable for transplantation were obtained from Moorfields Lions Eye Bank. At the wet lab, graft stripping was performed by scoring the peripheral endothelium. The trypan blue positive cells (TBPC) and cell density (cells/mm2—reticule count) were counted manually before and after stripping. The procedural time, peripheral and central tears and complete peel-off were also re

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Lohmann, Tibor, Sabine Baumgarten, Niklas Plange, Peter Walter, and Matthias Fuest. "Effects of uncomplicated Descemet membrane endothelial keratoplasty on the central retinal thickness." Graefe's Archive for Clinical and Experimental Ophthalmology 259, no. 9 (2021): 2731–41. http://dx.doi.org/10.1007/s00417-021-05203-2.

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Abstract Purpose To determine retinal thickness (RT) changes and the incidence of macular edema after uncomplicated Descemet membrane endothelial keratoplasty (DMEK-ME) in patients without ME risk factors. Methods In this retrospective study, 107 pseudophakic eyes of 74 patients with Fuchs endothelial dystrophy (FED) (79.4%) or bullous keratopathy (BK) (20.6%) underwent DMEK surgery between 2016 and 2019 at the Department of Ophthalmology, RWTH Aachen University. Patients with intra- or postoperative complications as well as pre-existing risk factors for ME were excluded. Macular spectral-doma

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Romano, Vito, Luca Pagano, Kunal A. Gadhvi, et al. "Clinical outcomes of pre-loaded ultra-thin DSAEK and pre-loaded DMEK." BMJ Open Ophthalmology 5, no. 1 (2020): e000546. http://dx.doi.org/10.1136/bmjophth-2020-000546.

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ObjectiveTo compare clinical outcomes and complications between pre-loaded ultra-thin Descemet stripping automated endothelialkeratoplasty (pl-UT-DSAEK) and pre-loaded Descemet membrane endothelial keratoplasty (pl-DMEK).Methods and analysisComparative study in patients with endothelial dysfunction associated with Fuchs endothelial corneal dystrophy and pseudophakic bullous keratopathy who underwent pl-UT-DSAEK or pl-DMEK transplants. For both groups, the tissues were pre-loaded at the Fondazione Banca degli Occhi del Veneto (Venice, Italy) and shipped to The Royal Liverpool University Hospita

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Viola, Pietro, Enrico Neri, Tommaso Occhipinti, et al. "Predicting Long-Term Endothelial Cell Loss after Preloaded Descemet Membrane Endothelial Keratoplasty in Fuchs’ Endothelial Corneal Dystrophy: A Mathematical Model." Journal of Clinical Medicine 13, no. 3 (2024): 877. http://dx.doi.org/10.3390/jcm13030877.

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(1) Background: This study offers a biexponential model to estimate corneal endothelial cell decay (ECD) following preloaded “endothelium-in” Descemet membrane endothelial keratoplasty (DMEK) in Fuchs’ endothelial corneal dystrophy (FECD) patients; (2) Methods: A total of 65 eyes undergoing DMEK alone or combined with cataract surgery were evaluated. The follow-up period was divided into an early phase (first 6 months) and a late phase (up to 36 months). Endothelial cell count (ECC) and endothelial cell loss (ECL) were analyzed; (3) Results: The half time of the ECD was 3.03 months for the ear

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Terry, Mark A., Michael D. Straiko, Peter B. Veldman, et al. "Standardized DMEK Technique." Cornea 34, no. 8 (2015): 845–52. http://dx.doi.org/10.1097/ico.0000000000000479.

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Schmidt, Manuela, Andreas Mößner, Renate Wiedemann, Christian Girbardt, and Jan Darius Unterlauft. "DMEK à chaud." Der Ophthalmologe 117, no. 1 (2019): 69–72. http://dx.doi.org/10.1007/s00347-019-0888-0.

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Mechleb, Nicole, Maria Rizk, Guillaume Debellemanière, Damien Gatinel, and Alain Saad. "Ten years of Descemet membrane endothelial keratoplasty: Identifying risk factors and early failure signs." Indian Journal of Ophthalmology 73, no. 7 (2025): 1021–26. https://doi.org/10.4103/ijo.ijo_2273_24.

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Purpose: To evaluate the effect of surgical indications and complexity on long-term clinical outcomes in Descemet membrane endothelial keratoplasty (DMEK) and identify early signs of graft failure. Design: Retrospective case series of 105 patients who underwent DMEK from March 2012 to December 2014. Methods: Surgical results were analyzed at 1 year, 3 years, 5 years, and 10 years based on surgical indication: fuchs endothelial dystrophy (FECD) (n = 47) and bullous keratopathy (BK) (n = 58), and on the presence of anterior segment comorbidities: simple (n = 63) versus complex (n = 42) DMEK. Res

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Bhandari, Vipul, Jagdeesh K. Reddy, Kirti Relekar, and Vijayalakshmi Prabhu. "Descemet’s Stripping Automated Endothelial Keratoplasty versus Descemet’s Membrane Endothelial Keratoplasty in the Fellow Eye for Fuchs Endothelial Dystrophy: A Retrospective Study." BioMed Research International 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/750567.

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Aim. To evaluate visual outcome and endothelial cell density (ECD) after Descemet’s Membrane Endothelial Keratoplasty (DMEK) in comparison with Descemet’s Stripping Automated Endothelial Keratoplasty (DSAEK) in the fellow eye for Fuchs endothelial dystrophy (FED).Design. Single-centre, retrospective case series.Methods. 30 eyes of 30 patients undergoing DMEK, who completed a 1-year follow-up, were compared with 30 fellow eyes which underwent DSAEK for bilateral FED. Main outcome measures studied included Best Corrected Visual Acuity (BCVA) and ECD during a 1-year follow-up period.Results. BCVA

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Marques, Raquel Esteves, Paulo Silva Guerra, David Cordeiro Sousa, Ana Inês Gonçalves, Ana Miguel Quintas, and Walter Rodrigues. "DMEK versus DSAEK for Fuchs’ endothelial dystrophy: A meta-analysis." European Journal of Ophthalmology 29, no. 1 (2018): 15–22. http://dx.doi.org/10.1177/1120672118757431.

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Purpose: To compare the safety and efficacy profiles of Descemet membrane endothelial keratoplasty (DMEK) and Descemet stripping automated endothelial keratoplasty (DSAEK) in adult patients with Fuchs’ endothelial dystrophy. Methods: Electronic database search on MEDLINE and CENTRAL from inception to August 2017. We included all comparative studies of DMEK versus DSAEK in patients with diagnosed Fuchs’ endothelial dystrophy. Studies assessing rescue procedures were excluded to minimize bias. Primary outcome: mean difference in best-corrected visual acuity (BCVA) at 3, 6, and 12 months postoper

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Zygoura, Vasiliki, Lamis Baydoun, Lisanne Ham, et al. "Quarter-Descemet membrane endothelial keratoplasty (Quarter-DMEK) for Fuchs endothelial corneal dystrophy: 6 months clinical outcome." British Journal of Ophthalmology 102, no. 10 (2018): 1425–30. http://dx.doi.org/10.1136/bjophthalmol-2017-311398.

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Background/aimTo assess the clinical outcome of the first series of Quarter-Descemet membrane endothelial keratoplasty (Quarter-DMEK), a potential hybrid technique between ‘descemetorhexis only’ and conventional, circular DMEK.MethodsProspective interventional case series at a tertiary referral centre. Twelve eyes of 12 patients with central Fuchs endothelial corneal dystrophy underwent Quarter-DMEK, that is, transplantation of one quadrant of a full-diameter DMEK graft, and were evaluated for best-corrected visual acuity (BCVA), endothelial cell density (ECD) and complications up to 6 months

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Oganesyan, Oganes G., P. V. Makarov, A. A. Grdikanyan, and V. R. Getadaryan. "THE TRANSPLANTATION OF DESCEMET’S MEMBRANE WITH ENDOTHELIUM IN COMPLICATED CLINICAL SITUATIONS." Medical Journal of the Russian Federation 24, no. 3 (2018): 129–34. http://dx.doi.org/10.18821/0869-2106-2018-24-3-129-134.

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The transplantation of Descemet's membrane with endothelium (DMEK) is the most efficient method of treatment of endothelium pathology. However, it is considered that at certain clinical situations DMEK is inappropriate. The purpose of study is to analyze the results of DMEK in complicated clinical situations. Materials and methods. The sampling included 14 patients (16 eyes) with pathology of endothelium of primary (19%) and secondary (81%) genesis and with concomitant alterations, including: total lack of vitreous (19%), non-posterior chamber pseudophakia (25%), presence of Ahmed drainage (25

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Arnalich-Montiel, Francisco, Ane Pérez-Sarriegui, and Alfonso Casado. "Impact of Introducing 2 Simple Technique Modifications on the Descemet Membrane Endothelial Keratoplasty Learning Curve." European Journal of Ophthalmology 27, no. 1 (2016): 16–20. http://dx.doi.org/10.5301/ejo.5000808.

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Purpose To analyze the impact of performing premarking of the Descemet roll and using SF6 20% on a surgeon's Descemet membrane endothelial keratoplasty (DMEK) learning process. Methods A total of 30 consecutive eyes with endothelial dysfunction undergoing DMEK during the learning curve of a surgeon were retrospectively analyzed. Prior to the study, the surgeon had already performed 10 DMEKs. The first 15 consecutive patients were included in group 1 (no premarking and air tamponade) and the other 15 consecutive patients were included in group 2 (premarking and SF6 tamponade). Main outcome para

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Aiello, Francesco, Francesco Matarazzo, Maria Phylactou, Kirithika Muthusamy, and Vincenzo Maurino. "Endothelial Keratoplasty Following Glaucoma Filtration Surgery: A UK Tertiary Eye Care Referral Centre Experience." Journal of Clinical Medicine 13, no. 20 (2024): 6097. http://dx.doi.org/10.3390/jcm13206097.

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Purpose: To compare the postoperative complications and clinical outcomes of Descemet membrane endothelial keratoplasty (DMEK) and Descemet stripping automated endothelial keratoplasty (DSAEK) in eyes with previous glaucoma filtering surgery. Methods: In this retrospective comparative case series, we analysed postoperative visual acuity and intraocular pressure, graft survival, rate of graft detachment and/or dislocation, number of rebubbling and/or graft repositioning procedures, and graft rejection or failure (primary and secondary). Results: Sixteen eyes with DMEK and 80 eyes with DSAEK wit

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Luft, N., M. Dirisamer, and S. Priglinger. "Descemet-Membran-Endothelkeratoplastik (DMEK)." Klinische Monatsblätter für Augenheilkunde 234, no. 03 (2016): 354–64. http://dx.doi.org/10.1055/s-0042-105156.

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ZusammenfassungDie Descemet-Membran-Endothelkeratoplastik (DMEK) stellt den Goldstandard in der Therapie von isolierten Erkrankungen des Hornhautendothels dar, allen voran der Fuchs-Endotheldystrophie. Durch ihre überlegenen Visusergebnisse und aufgrund der niedrigeren und weiter sinkenden Komplikationsrate macht sie der weltweit etablierten Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) den Rang streitig. Die Etablierung einer standardisierten und reproduzierbaren DMEK-Methode und Fortschritte im Bereich der Spendergewebspräparation ebnen den Weg für viele Chirurgen, sich diese

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Ní Dhubhghaill, Sorcha, Alina Miron, Jessica T. Lie, Isabel Dapena, Silke Oellerich, and Gerrit R. J. Melles. "Preclinical testing of small diameter Descemet membrane endothelial keratoplasty grafts to increase tissue availability." PLOS ONE 16, no. 2 (2021): e0246516. http://dx.doi.org/10.1371/journal.pone.0246516.

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In this study, we describe a process of preparing, surgically manipulating, and validating a novel “small diameter” 4mm circular Descemet membrane endothelial keratoplasty (DMEK) graft in vitro. Three small diameter DMEK grafts can be prepared from a single donor endothelium and could, therefore, potentially expand the donor pool. Prior to clinical use, however, we aimed to examine each step of the process to determine the effect on the endothelial cell loss and whether or not cells retained their capacity to migrate uniformly. For this study, circular small diameter grafts, obtained from twel

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Parker, Jack, John S. Parker, and Gerrit RJ Melles. "Descemet Membrane Endothelial Keratoplasty—A Review." US Ophthalmic Review 06, no. 01 (2013): 29. http://dx.doi.org/10.17925/usor.2013.06.01.29.

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Descemet membrane endothelial keratoplasty (DMEK) is the most recent step forward in the evolution of endothelial keratoplasty toward thinner grafts and more natural, anatomic corneal restoration. Offering unprecedented visual results and requiring no special or expensive equipment, DMEK has the potential to become the first line treatment for corneal endothelial disorders. The surgery’s perceived shortcomings (primarily technical difficulty) have mostly been addressed by new ‘no-touch’ procedures for both graft preparation and graft unfolding in the recipient eye. And as a result, DMEK has be

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Singh, Shalini, Priyanka Pantola, Sunita Chaurasia, Sujata Das, and Somasheila Murthy. "Review of current methods of preparation and distribution of DMEK graft at the eye banks." Indian Journal of Ophthalmology 73, no. 1 (2024): 19–27. https://doi.org/10.4103/ijo.ijo_243_24.

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The scope of eye banking activities has been expanding with the advances and techniques of keratoplasty. With the popularity of descemet membrane endothelial keratoplasty (DMEK) in the recent decade, there is a need to adopt the preparation of DMEK tissues in the eye banks. This necessitated surgical training of the eye bank technicians, development of infrastructure in the eye bank, innovative methods of graft preparation, and delivery for the surgery at distant surgery centers. Eye banks across various countries have devised and adopted different methods of providing DMEK grafts based on the

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Szalai, Eszter, Michael W. Belin, Zsuzsanna Szijártó, and Adrienne Csutak. "Visual Recovery and Endothelial Repopulation after DMEK Graft Removal and Vitrectomy for Late Endophthalmitis: A Case Report." Case Reports in Ophthalmology 15, no. 1 (2024): 736–41. http://dx.doi.org/10.1159/000541644.

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Introduction: The aim of the study was to report a unique case with excellent clinical outcomes after late endophthalmitis following Descemet’s membrane endothelial keratoplasty (DMEK) surgery requiring donor graft removal without replacement. Case Presentation: A 67-year-old female with a prior ocular history of bilateral cataract surgery, Fuchs endothelial dystrophy, and pseudophakic DMEK in the left eye presented with endophthalmitis 2 months after keratoplasty. DMEK graft removal without replacement with an intracameral washout, pars plana vitrectomy, intracameral, and intravitreal antibio

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López, Ester Fernández, and Cristina Peris Martínez. "Descemet Membrane Endothelial Keratoplasty for Corneal Decompensation Secondary to Phakic Intraocular Lenses." Journal of Ophthalmology 2019 (October 27, 2019): 1–7. http://dx.doi.org/10.1155/2019/2038232.

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Purpose. To describe the surgical technique and clinical outcomes of bilensectomy (pIOL explant and phacoemulsification), followed by DMEK performed for bullous keratopathy secondary to pIOL. Methods. Seven eyes of seven patients, who developed corneal decompensation after pIOL implantation, underwent bilensectomy followed by DMEK in a two-step procedure. Main outcome measures included uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), refraction, endothelial cell density (ECD) at 1, 3, 6, and 12 months, and intraoperative and postoperative complications. Results. DMEK w

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Nanavaty, Mayank A., Ritika Mukhija, and Gabriella Quiney. "Correlation between recipient age and visual acuity after Descemet’s membrane endothelial keratoplasty in Fuchs endothelial dystrophy." Journal of Cornea and Ocular Surface 1, no. 2 (2023): 102–6. http://dx.doi.org/10.4103/jcos.jcos_22_23.

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Abstract Objectives: To analyze the correlation between the recipient’s age and best corrected distance visual acuity (BCDVA) after Descemet’s membrane endothelial keratoplasty (DMEK). Materials and Methods: Design: Retrospective study. Setting: Institutional, tertiary care eye hospital. Study Population: All patients who underwent DMEK or DMEK combined with phacoemulsification (DMEK triple) for Fuchs Endothelial Dystrophy, using a standardized protocol between August 2016 and July 2021, were included. Previous glaucoma surgery, aphakia, or complicated pseudophakia were excluded. Main Outcome

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Torras-Sanvicens, Josep, Irene Blanco-Domínguez, José-María Sánchez-González, et al. "Visual Quality and Subjective Satisfaction in Ultrathin Descemet Stripping Automated Endothelial Keratoplasty (UT-DSAEK) versus Descemet Membrane Endothelial Keratoplasty (DMEK): A Fellow-Eye Comparison." Journal of Clinical Medicine 10, no. 3 (2021): 419. http://dx.doi.org/10.3390/jcm10030419.

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Background: To analyze objective and subjective visual quality differences between descemet membrane endothelial keratoplasty (DMEK) and ultra-thin descemet stripping automated endothelial keratoplasty (UT-DSAEK) with a paired contralateral-eye design. Methods: A cross-sectional, comparative, and observational case series study between DMEK and UT-DSAEK were presented. Visual acuity, refractive status and corneal quality assessment were compared between both endothelial keratoplasty techniques. The sample consisted of 20 eyes (10 patients) diagnosed with Fuchs endothelial corneal dystrophy. Al

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Satue, Maria, Miriam Idoipe, Alicia Gavin, et al. "Early Changes in Visual Quality and Corneal Structure after DMEK: Does DMEK Approach Optical Quality of a Healthy Cornea?" Journal of Ophthalmology 2018 (September 23, 2018): 1–8. http://dx.doi.org/10.1155/2018/2012560.

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Purpose. To evaluate early changes in visual function and visual quality parameters after Descemet membrane endothelial keratoplasty (DMEK) and to compare the outcomes with healthy controls. Methods. Thirteen patients who underwent DMEK and 14 controls were evaluated. All subjects underwent visual function evaluation, including visual acuity under photopic and mesopic lighting conditions and contrast sensitivity (CSV) tests CSV 1000 and Pelli-Robson. Corneal parameters were assessed with Oculus Pentacam. Corneal mean keratometry (Km), corneal densitometry values, and low and high order aberrat

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Bichet, Pierre, Rémi Moskwa, Christophe Goetz, Yinka Zevering, Jean-Charles Vermion, and Jean-Marc Perone. "Five-year clinical outcomes of 107 consecutive DMEK surgeries." PLOS ONE 18, no. 12 (2023): e0295434. http://dx.doi.org/10.1371/journal.pone.0295434.

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Purpose The long-term clinical outcomes, postoperative complications, and graft survival of Descemet-membrane endothelial keratoplasty (DMEK) remain poorly understood. We retrospectively assessed these variables in all consecutive eyes that underwent DMEK for any indication in 2014–2018. The findings were compared to the long-term DMEK studies of five other groups (3–10-year follow-up). Methods Patients underwent ophthalmological tests preoperatively, at 1, 3, 6, and 12 postoperative months, and then annually. Five-year graft survival was determined by Kaplan-Meier estimator. Change in best-co

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Sela, Tal Corina, Moti Iflah, Khitam Muhsen, and Alon Zahavi. "Descemet membrane endothelial keratoplasty compared with ultrathin Descemet stripping automated endothelial keratoplasty: a meta-analysis." BMJ Open Ophthalmology 8, no. 1 (2023): e001397. http://dx.doi.org/10.1136/bmjophth-2023-001397.

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AimsThis study aims to compare the clinical outcome of Descemet membrane endothelial keratoplasty (DMEK) and ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) in patients with corneal endothelial dysfunction due to Fuchs’ endothelial dystrophy or pseudophakic bullous keratopathy.MethodsWe conducted a meta-analysis using a literature search of Embase, PubMed, Cochrane CENTRAL, ClinicalTrials.gov and WHO ICTRP databases. We included randomised controlled trials (RCTs) and cohort studies that compared DMEK and UT-DSAEK (graft<130 µm), with a follow-up of ≥12 months, pu

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Saad, Alain, Emmanuel Guilbert, Alice Grise-Dulac, Patrick Sabatier, and Damien Gatinel. "Intraoperative OCT-Assisted DMEK." Cornea 34, no. 7 (2015): 802–7. http://dx.doi.org/10.1097/ico.0000000000000462.

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McKee, Hamish D., and Vishal Jhanji. "Learning DMEK From YouTube." Cornea 36, no. 12 (2017): 1477–79. http://dx.doi.org/10.1097/ico.0000000000001399.

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Cursiefen, C., and F. E. Kruse. "DMEK: posteriore lamelläre Keratoplastiktechnik." Der Ophthalmologe 107, no. 4 (2010): 370–76. http://dx.doi.org/10.1007/s00347-010-2155-2.

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Lazaridis, Apostolos, Ourania Fydanaki, Eleftherios Giallouros, et al. "Recovery of Corneal Clarity After DMEK Followed by Rebubbling Versus Uneventful DMEK." Cornea 37, no. 7 (2018): 840–47. http://dx.doi.org/10.1097/ico.0000000000001554.

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Rickmann, Annekatrin, Silke Wahl, Nicola Hofmann, et al. "Precut DMEK Using Dextran-Containing Storage Medium Is Equivalent to Conventional DMEK." Cornea 38, no. 1 (2019): 24–29. http://dx.doi.org/10.1097/ico.0000000000001778.

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Ang, Marcus, Adam M. Dubis, and Mark R. Wilkins. "Descemet Membrane Endothelial Keratoplasty: Intraoperative and Postoperative Imaging Spectral-Domain Optical Coherence Tomography." Case Reports in Ophthalmological Medicine 2015 (2015): 1–4. http://dx.doi.org/10.1155/2015/506251.

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We describe a case report of using the same handheld spectral-domain anterior segment optical coherence tomography (ASOCT) for rapid intraoperative and postoperative imaging in a case of Descemet membrane endothelial keratoplasty (DMEK). A 67-year-old woman, with Fuchs dystrophy and corneal decompensation, underwent DMEK with intraoperative ASOCT imaging using the handheld Envisu spectral domain ASOCT system (Bioptigen, Inc., Morrisville, NC, USA). We found that this easy-to-use portable system with handheld probe allowed for rapid imaging of the anterior segment during donor manipulation to v

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Gilazhov, Y. G., D. K. Kulbatyrov, M. D. Urazgalieva, and K. R. Maksot. "Efficiency of oxygenates on increase of octane number of reforming gasoline." Neft i Gaz, no. 3 (June 30, 2024): 136–47. http://dx.doi.org/10.37878/2708-0080/2024-3.11.

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At present, gasoline occupies one of the leading places among primary energy sources. The need of mankind in it, in its high quality, is greater than in any other fraction of hydrocarbons. Therefore, very high requirements are made to the operational properties of automobile gasoline, and the problem of improving the quality of gasoline is one of the urgent problems of the chemical industry. Modern vehicles require fuel with a high-octane number with properties preventing detonation and having octane numbers of 92, 95 and 98 for engines. High anti-detonation performance can be achieved through

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Machalińska, Anna, Agnieszka Kuligowska, Bogna Kowalska, and Krzysztof Safranow. "Comparative Analysis of Corneal Parameters in Swept-Source Imaging between DMEK and UT-DSAEK Eyes." Journal of Clinical Medicine 10, no. 21 (2021): 5119. http://dx.doi.org/10.3390/jcm10215119.

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Background: The need to provide a comparative analysis of corneal parameter changes compared to their preoperative values between Descemet membrane endothelial keratoplasty (DMEK) and ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) patients. Methods: The study included 24 eyes after UT-DSAEK and 24 eyes after DMEK. Visual acuity, endothelial cell count (ECC), central corneal thickness (CCT), mean keratometry (MK), mean astigmatism (MA), astigmatism asymmetry (AA) and higher-order aberrations (HOAs) were assessed at baseline and 1, 3, 6 and 12 months after the surgery

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Agha, Bishr, Nura Ahmad, Daniel G. Dawson, Thomas Kohnen, and Ingo Schmack. "Refractive outcome and tomographic changes after Descemet membrane endothelial keratoplasty in pseudophakic eyes with Fuchs’ endothelial dystrophy." International Ophthalmology 41, no. 8 (2021): 2897–904. http://dx.doi.org/10.1007/s10792-021-01850-w.

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Abstract Purpose To analyze refractive and topographic changes secondary to Descemet membrane endothelial keratoplasty (DMEK) in pseudophakic eyes with Fuchs’ endothelial dystrophy (FED). Methods Eighty-seven pseudophakic eyes of 74 patients who underwent subsequent DMEK surgery for corneal endothelial decompensation and associated visual impairment were included. Median post-operative follow-up time was 12 months (range: 3–26 months). Main outcome measures were pre- and post-operative manifest refraction, anterior and posterior corneal astigmatism, simulated keratometry (CASimK) and Q value o

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Ruzza, Alessandro, Stefano Ferrari, Matteo Airaldi, Vito Romano, and Diego Ponzin. "Effect of Low-Temperature Preservation in Optisol-GS on Preloaded, Endothelium-Out DMEK Grafts." Journal of Clinical Medicine 12, no. 3 (2023): 1026. http://dx.doi.org/10.3390/jcm12031026.

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The aim of the study was to assess different temperature ranges for the preservation of pre-loaded Descemet Membrane Endothelial Keratoplasty (DMEK) grafts in the DMEK RAPID Mini device. Methods: Three groups of 15 DMEK grafts (five per group) were pre-loaded in the DMEK RAPID Mini and preserved in Optisol-GS for 72 h at different temperatures: group A at >8 °C, group B between 2–8 °C and group C at <2 °C. After stripping and preservation, the viability of the endothelium, cell loss and morphology were assessed through light microscopy following trypan blue and alizarin red staining. Res

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Srinivas, Tara, Christine Wang, and Allen O. Eghrari. "Feasibility of Descemet Membrane Endothelial Keratoplasty With Preloaded and Trifolded Graft After 96-Hour Storage and Shipping." Eye Banking and Corneal Transplantation 4, no. 2 (2025): e0036. https://doi.org/10.1097/ebct.0000000000000036.

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Purpose: Descemet membrane endothelial keratoplasty (DMEK) donor grafts can be safely trifolded, preloaded, and shipped for up to 96 hours without significant endothelial cell loss; however, clinical outcomes of such storage times have yet to be reported in human patients. Here, we report a case of a trifolded, preloaded DMEK graft stored for 96 hours and transplanted in a 68-year-old woman with Fuchs endothelial dystrophy. Methods: DMEK graft was preloaded and trifolded with postprocessing endothelial cell density of 2558 cells/mm2. Intraoperatively, it was pulled into the anterior chamber wi

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Kronschläger, Martin, Alessandro Ruzza, Johannes Zeilinger, Andreas Schlatter, Manuel Ruiss, and Oliver Findl. "Comparison of rebubbling rate between preloaded endothelium-in and preloaded no-touch endothelium-out Descemet membrane endothelial keratoplasty transplantation." BMC Ophthalmology 24, no. 1 (2024). http://dx.doi.org/10.1186/s12886-024-03560-0.

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Abstract Background To compare the difference in rebubbling rates between patients undergoing Descemet membrane endothelial keratoplasty (DMEK) with endothelium-in using a standard IOL cartridge and those with endothelium-out DMEK utilizing a no-touch technique with borosilicate glass cartridge transplantation. Methods This retrospective study included all eyes that underwent preloaded endothelium-in or endothelium-out DMEK transplantation from June 2019 to December 2023 at the Hanusch Hospital, Vienna, Austria. All DMEKs were harvested, prepared and preloaded at the European Eye Bank of Venic

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Schöneberger, Verena, Volkan Tahmaz, Leonie Menghesha, et al. "Retinal Detachment Rates After Uncomplicated DMEK Versus Cataract Surgery Combined (Triple-)DMEK." Cornea, April 25, 2024. http://dx.doi.org/10.1097/ico.0000000000003554.

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Purpose: To evaluate the rate of and risk factors for rhegmatogenous retinal detachment (RRD) after Descemet membrane endothelial keratoplasty (DMEK) either alone or in combination with cataract surgery. Design: Retrospective analysis of prospective database. Methods: Consecutive eyes with Fuchs endothelial corneal dystrophy (FECD) that received DMEK surgery with a minimum follow-up of 1 year between July 2011 and January 2021 at the Department of Ophthalmology at the University of Cologne were analyzed. Exclusion criteria were complicated history including repeat DMEK within 1-year, previous

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Maier, Anna-Karina B., Daniel Pilger, Enken Gundlach, Sibylle Winterhalter, Necip Torun, and Tina Dietrich-Ntoukas. "Graft failure rate and complications after Descemet membrane endothelial keratoplasty in eyes with pre-existing glaucoma." Graefe's Archive for Clinical and Experimental Ophthalmology, August 30, 2022. http://dx.doi.org/10.1007/s00417-022-05813-4.

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Abstract Purpose To evaluate the outcome of Descemet Membrane Endothelial Keratoplasty (DMEK) in eyes with pre-existing glaucoma. Design In this retrospective, observational case series we included data of 150 consecutive DMEKs in eyes with pre-existing glaucoma of 150 patients after excluding data of the second treated eye of each patient and of re-DMEKs during follow-up. Cumulative incidences of IOP elevation (IOP > 21 mmHg or ≥ 10 mmHg increase in IOP from preoperative value), post-DMEK glaucoma (need of an additional intervention due to worsening of the IOP), graft rejection, and graft

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Cheong, Ezekiel Ze Ken, Qiu Ying Wong, Howard Cajucom-Uy, Hla Myint Htoon, and Marcus Ang. "Clinical outcomes in imported endothelium-in preloaded vs. surgeon-loaded DMEKs in Asian eyes." Frontiers in Medicine 12 (May 13, 2025). https://doi.org/10.3389/fmed.2025.1580733.

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PurposeTo perform a direct, prospective, comparative analysis of the complications associated with imported preloaded grafts versus surgeon-loaded grafts in Descemet membrane endothelial keratoplasty (DMEK) in Asian eyes.MethodsA total of 20 consecutive preloaded DMEKs were matched by donor age with 40 surgeon-loaded DMEKs for the indications of Fuchs’ endothelial cell dystrophy (FECD) and pseudophakic bullous keratopathy (PBK). All cases of preloaded and surgeon-loaded DMEKs were by a single surgeon in the Singapore National Eye Centre and utilized endothelium-in pull-through cartridges (CORO

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Droutsas, Konstantinos, Palaiologos Alexopoulos, Ioannis Giachos, Eleftherios Giallouros, Walter Sekundo, and Apostolos Lazaridis. "Secondary DMEK following failed primary DMEK." International Ophthalmology, June 2, 2021. http://dx.doi.org/10.1007/s10792-021-01890-2.

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