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Journal articles on the topic 'Dmi3'

Author: Grafiati

Published: 4 June 2021

Last updated: 9 February 2022

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1

Ané, Jean-Michel, Julien Lévy, Philippe Thoquet, et al. "Genetic and Cytogenetic Mapping of DMI1, DMI2, and DMI3 Genes of Medicago truncatula Involved in Nod Factor Transduction, Nodulation, and Mycorrhization." Molecular Plant-Microbe Interactions® 15, no. 11 (2002): 1108–18. http://dx.doi.org/10.1094/mpmi.2002.15.11.1108.

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The DMI1, DMI2, and DMI3 genes of Medicago truncatula, which are required for both nodulation and mycorrhization, control early steps of Nod factor signal transduction. Here, we have used diverse approaches to pave the way for the map-based cloning of these genes. Molecular amplification fragment length polymorphism markers linked to the three genes were identified by bulked segregant analysis. Integration of these markers into the general genetic map of M. truncatula revealed that DMI1, DMI2, and DMI3 are located on linkage groups 2, 5, and 8, respectively. Cytogenetic studies using fluoresce

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2

Messinese, Elsa, Jeong-Hwan Mun, Li Huey Yeun, et al. "A Novel Nuclear Protein Interacts With the Symbiotic DMI3 Calcium- and Calmodulin-Dependent Protein Kinase of Medicago truncatula." Molecular Plant-Microbe Interactions® 20, no. 8 (2007): 912–21. http://dx.doi.org/10.1094/mpmi-20-8-0912.

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Many higher plants establish symbiotic relationships with arbuscular mycorrhizal (AM) fungi that improve their ability to acquire nutrients from the soil. In addition to establishing AM symbiosis, legumes also enter into a nitrogen-fixing symbiosis with bacteria known as rhizobia that results in the formation of root nodules. Several genes involved in the perception and transduction of bacterial symbiotic signals named “Nod factors” have been cloned recently in model legumes through forward genetic approaches. Among them, DMI3(Doesn't Make Infections 3) is a calcium- and calmodulin-dependent k

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3

Bersoult, Anne, Sylvie Camut, Ariana Perhald, Attila Kereszt, György B. Kiss, and Julie V. Cullimore. "Expression of the Medicago truncatula DMI2 Gene Suggests Roles of the Symbiotic Nodulation Receptor Kinase in Nodules and During Early Nodule Development." Molecular Plant-Microbe Interactions® 18, no. 8 (2005): 869–76. http://dx.doi.org/10.1094/mpmi-18-0869.

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The Medicago truncatula DMI2 gene encodes a receptorlike kinase required for establishing root endosymbioses. The DMI2 gene was shown to be expressed much more highly in roots and nodules than in leaves and stems. In roots, its expression was not altered by nitrogen starvation or treatment with lipochitooligosaccharidic Nod factors. Moreover, the DMI2 mRNA abundance in roots of the nfp, dmi1, dmi3, nsp1, nsp2, and hcl symbiotic mutants was similar to the wild type, whereas lower levels in some dmi2 mutants could be explained by regulation by the nonsense-mediated decay, RNA surveillance mechan

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4

Godfroy, Olivier, Frédéric Debellé, Ton Timmers, and Charles Rosenberg. "A Rice Calcium- and Calmodulin-Dependent Protein Kinase Restores Nodulation to a Legume Mutant." Molecular Plant-Microbe Interactions® 19, no. 5 (2006): 495–501. http://dx.doi.org/10.1094/mpmi-19-0495.

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The Medicago truncatula DMI3 gene encodes a calcium- and calmodulin-dependent protein kinase (CCaMK) that is necessary for the establishment of both rhizobial and mycorrhizal symbioses. The two symbiotic signaling pathways diverge downstream of DMI3; therefore, it has been proposed that legumes have evolved a particular form of CCaMK, acting like a switch able both to discriminate between rhizobial and mycorrhizal calcium signatures and to trigger the appropriate downstream signaling pathway. To test this hypothesis, we examined whether a CCaMK gene from a nonlegume species was able to restore

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5

Ovchinnikova, Evgenia, Etienne-Pascal Journet, Mireille Chabaud, et al. "IPD3 Controls the Formation of Nitrogen-Fixing Symbiosomes in Pea and Medicago Spp." Molecular Plant-Microbe Interactions® 24, no. 11 (2011): 1333–44. http://dx.doi.org/10.1094/mpmi-01-11-0013.

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A successful nitrogen-fixing symbiosis requires the accommodation of rhizobial bacteria as new organelle-like structures, called symbiosomes, inside the cells of their legume hosts. Two legume mutants that are most strongly impaired in their ability to form symbiosomes are sym1/TE7 in Medicago truncatula and sym33 in Pisum sativum. We have cloned both MtSYM1 and PsSYM33 and show that both encode the recently identified interacting protein of DMI3 (IPD3), an ortholog of Lotus japonicus (Lotus) CYCLOPS. IPD3 and CYCLOPS were shown to interact with DMI3/CCaMK, which encodes a calcium- and calmodu

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6

Amiour, Nardjis, Ghislaine Recorbet, Franck Robert, Silvio Gianinazzi, and Eliane Dumas-Gaudot. "Mutations in DMI3 and SUNN Modify the Appressorium-Responsive Root Proteome in Arbuscular Mycorrhiza." Molecular Plant-Microbe Interactions® 19, no. 9 (2006): 988–97. http://dx.doi.org/10.1094/mpmi-19-0988.

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Modification of the Medicago truncatula root proteome during the early stage of arbuscular mycorrhizal symbiosis was investigated by comparing, using two-dimensional electrophoresis, the protein patterns obtained from non-inoculated roots and roots synchronized for Glomus intraradices appressorium formation. This approach was conducted in wild-type (J5), mycorrhiza-defective (TRV25, dmi3), and autoregulation-defective (TR122, sunn) M. truncatula genotypes. The groups of proteins that responded to appressorium formation were further compared between wild-type and mutant genotypes; few overlaps

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7

Seddas, Pascale M. A., Cecilia M. Arias, Christine Arnould, et al. "Symbiosis-Related Plant Genes Modulate Molecular Responses in an Arbuscular Mycorrhizal Fungus During Early Root Interactions." Molecular Plant-Microbe Interactions® 22, no. 3 (2009): 341–51. http://dx.doi.org/10.1094/mpmi-22-3-0341.

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To gain further insight into the role of the plant genome in arbuscular mycorrhiza (AM) establishment, we investigated whether symbiosis-related plant genes affect fungal gene expression in germinating spores and at the appressoria stage of root interactions. Glomus intraradices genes were identified in expressed sequence tag libraries of mycorrhizal Medicago truncatula roots by in silico expression analyses. Transcripts of a subset of genes, with predicted functions in transcription, protein synthesis, primary or secondary metabolism, or of unknown function, were monitored in spores and germi

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8

Proffer, Tyre J., Raffaele Berardi, Zhonghua Ma, et al. "Occurrence, Distribution, and Polymerase Chain Reaction-Based Detection of Resistance to Sterol Demethylation Inhibitor Fungicides in Populations of Blumeriella jaapii in Michigan." Phytopathology® 96, no. 7 (2006): 709–17. http://dx.doi.org/10.1094/phyto-96-0709.

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The intensive use of site-specific fungicides in agricultural production provides a potent selective mechanism for increasing the frequency of fungicide-resistant isolates in pathogen populations. Practical resistance occurs when the frequency and levels of resistance are great enough to limit the effectiveness of disease control in the field. Cherry leaf spot (CLS), caused by the fungus Blumeriella jaapii, is a major disease of cherry trees in the Great Lakes region. The site-specific sterol demethylation inhibitor fungicides (DMIs) have been used extensively in the region. In 2002, CLS contr

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9

Ma, Zhonghua, Tyre J. Proffer, Janette L. Jacobs та George W. Sundin. "Overexpression of the 14α-Demethylase Target Gene (CYP51) Mediates Fungicide Resistance in Blumeriella jaapii". Applied and Environmental Microbiology 72, № 4 (2006): 2581–85. http://dx.doi.org/10.1128/aem.72.4.2581-2585.2006.

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ABSTRACT Sterol demethylation inhibitor (DMI) fungicides are widely used to control fungi pathogenic to humans and plants. Resistance to DMIs is mediated either through alterations in the structure of the target enzyme CYP51 (encoding 14α-demethylase), through increased expression of the CYP51 gene, or through increased expression of efflux pumps. We found that CYP51 expression in DMI-resistant (DMIR) isolates of the cherry leaf spot pathogen Blumeriella jaapii was increased 5- to 12-fold compared to that in DMI-sensitive (DMIS) isolates. Analysis of sequences upstream of CYP51 in 59 DMIR isol

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10

Parádi, István, Diederik van Tuinen, Dominique Morandi, et al. "Transcription of Two Blue Copper-Binding Protein Isogenes Is Highly Correlated with Arbuscular Mycorrhizal Development in Medicago truncatula." Molecular Plant-Microbe Interactions® 23, no. 9 (2010): 1175–83. http://dx.doi.org/10.1094/mpmi-23-9-1175.

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Expression profiling of two paralogous arbuscular mycorrhizal (AM)-specific blue copper-binding gene (MtBcp1a and MtBcp1b) isoforms was performed by real-time quantitative polymerase chain reaction in wild-type Medicago truncatula Jemalong 5 (J5) during the mycorrhizal development with Glomus intraradices for up to 7 weeks. Time-course analysis in J5 showed that expression of both MtBcp1 genes increased continuously and correlated strongly with the colonization intensity and arbuscule content. MtPT4, selected as a reference gene of the functional plant-fungus association, showed a weaker corre

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11

Rival, P., F. de Billy, J. J. Bono, C. Gough, C. Rosenberg, and S. Bensmihen. "Epidermal and cortical roles of NFP and DMI3 in coordinating early steps of nodulation in Medicago truncatula." Development 139, no. 18 (2012): 3383–91. http://dx.doi.org/10.1242/dev.081620.

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12

Papavassiliou, George C., George C. Anyfantis, and Ioannis B. Koutselas. "Some Air-stable Unsymmetrical Nickel 1,2-Dithiolenes with Extended Tetrathiafulvalenedithiolato Ligands." Zeitschrift für Naturforschung B 62, no. 12 (2007): 1481–86. http://dx.doi.org/10.1515/znb-2007-1203.

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The air-stable unsymmetrical complexes Ni(dt)(dmit), Ni(dt)(dmio), Ni(tmdt)(dmit), Ni(tmdt)(dmio), Ni(etdt)(dmit), Ni(etdt)(dmio), Ni(ptdt)(dmit), and Ni(ptdt)(dmio) (where dmit is 1,3-dithiol-2-thione-4,5-dithiolate, dmio is 1,3-dithiol-2-one-4,5-dithiolate, dt is tetrathiafulvalendithiolate, tmdt is trimethylenetetrathiafulvalenedithiolate, etdt is ethylenedithiotetrathiafulvalenedithiolate, and ptdt is propylenedithiotetrathiafulvalenedithiolate) were prepared and characterized analytically, electrochemically and spectroscopically. In the solid state, the compounds exhibit optical absorptio

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13

Weidmann, Stéphanie, Lisa Sanchez, Julie Descombin, Odile Chatagnier, Silvio Gianinazzi, and Vivienne Gianinazzi-Pearson. "Fungal Elicitation of Signal Transduction-Related Plant Genes Precedes Mycorrhiza Establishment and Requires the dmi3 Gene in Medicago truncatula." Molecular Plant-Microbe Interactions® 17, no. 12 (2004): 1385–93. http://dx.doi.org/10.1094/mpmi.2004.17.12.1385.

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Suppressive subtractive hybridization and expressed sequence tag sequencing identified 29 plant genes which are upregulated during the appressorium stage of mycorrhiza establishment between Medicago truncatula J5 (Myc+) and Glomus mosseae. Eleven genes coding plant proteins with predicted functions in signal transduction, transcription, and translation were investigated in more detail for their relation to early events of symbiotic interactions. Expression profiling showed that the genes are activated not only from the appressorium stage up to the fully established symbiosis in the Myc+ genoty

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14

Lee, Dae Young, Myung G. Lee, Hyun Sook Shin, and Inchul Lee. "Changes in omeprazole pharmacokinetics in rats with diabetes induced by alloxan or streptozotocin: Faster clearance of omeprazole due to induction of hepatic CYP1A2 and 3A1." Journal of Pharmacy & Pharmaceutical Sciences 10, no. 4 (2007): 420. http://dx.doi.org/10.18433/j3wc7g.

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Purpose. To investigate the effect of diabetes mellitus induced by alloxan (DMIA) or streptozotocin (DMIS) on the pharmacokinetics of omeprazole in rats. It has been reported that omeprazole is primarily metabolized via hepatic CYP1A2, 2D1, and 3A1 in rats. The expression and mRNA levels of hepatic CYP1A2 and 3A1 increases in DMIA and DMIS rats, but the expression of hepatic CYP2D1 does not change in DMIS rats. In addition, the metabolic activities of intestinal CYP3A1/2 decreases in DMIS rats. Thus, it could be expected that the pharmacokinetics of omeprazole would be affected by changes in b

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15

Ni, Lan, Xiaopu Fu, Huan Zhang, et al. "Abscisic Acid Inhibits Rice Protein Phosphatase PP45 via H2O2 and Relieves Repression of the Ca2+/CaM-Dependent Protein Kinase DMI3." Plant Cell 31, no. 1 (2018): 128–52. http://dx.doi.org/10.1105/tpc.18.00506.

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16

Sanchez, Lisa, Stéphanie Weidmann, Christine Arnould, Anne Rose Bernard, Silvio Gianinazzi, and Vivienne Gianinazzi-Pearson. "Pseudomonas fluorescens and Glomus mosseae Trigger DMI3-Dependent Activation of Genes Related to a Signal Transduction Pathway in Roots of Medicago truncatula." Plant Physiology 139, no. 2 (2005): 1065–77. http://dx.doi.org/10.1104/pp.105.067603.

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17

Horváth, Beatrix, Li Huey Yeun, Ágota Domonkos, et al. "Medicago truncatula IPD3 Is a Member of the Common Symbiotic Signaling Pathway Required for Rhizobial and Mycorrhizal Symbioses." Molecular Plant-Microbe Interactions® 24, no. 11 (2011): 1345–58. http://dx.doi.org/10.1094/mpmi-01-11-0015.

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Legumes form endosymbiotic associations with nitrogen-fixing bacteria and arbuscular mycorrhizal (AM) fungi which facilitate nutrient uptake. Both symbiotic interactions require a molecular signal exchange between the plant and the symbiont, and this involves a conserved symbiosis (Sym) signaling pathway. In order to identify plant genes required for intracellular accommodation of nitrogen-fixing bacteria and AM fungi, we characterized Medicago truncatula symbiotic mutants defective for rhizobial infection of nodule cells and colonization of root cells by AM hyphae. Here, we describe mutants i

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18

Venkateshwaran, Muthusubramanian, Dhileepkumar Jayaraman, Mireille Chabaud, et al. "A role for the mevalonate pathway in early plant symbiotic signaling." Proceedings of the National Academy of Sciences 112, no. 31 (2015): 9781–86. http://dx.doi.org/10.1073/pnas.1413762112.

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Rhizobia and arbuscular mycorrhizal fungi produce signals that are perceived by host legume receptors at the plasma membrane and trigger sustained oscillations of the nuclear and perinuclear Ca2+ concentration (Ca2+ spiking), which in turn leads to gene expression and downstream symbiotic responses. The activation of Ca2+ spiking requires the plasma membrane-localized receptor-like kinase Does not Make Infections 2 (DMI2) as well as the nuclear cation channel DMI1. A key enzyme regulating the mevalonate (MVA) pathway, 3-Hydroxy-3-Methylglutaryl CoA Reductase 1 (HMGR1), interacts with DMI2 and

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19

Anyfantis, G. C., G. C. Papavassiliou, A. Terzis, et al. "Preparation And Characterization Of Some Nickel 1,2-Dithiolene Complexes As Single-Component Semiconductors." Zeitschrift für Naturforschung B 61, no. 8 (2006): 1007–11. http://dx.doi.org/10.1515/znb-2006-0813.

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The unsymmetrical (mixed-ligand) nickel 1,2-dithiolene complexes Ni(pddt)(dmio) and Ni(pddt)(dmit) (where pddt is 6,7-dihydro-5H-1,4-dithiepin-2,3-dithiolate, dmio is 1,3-dithiol-2-one- 4,5-dithiolate, and dmit is 1,3-dithiol-2-thione-4,5-dithiolate) were synthesized and characterized. The new complexes were found to be soluble in organic solvents, from which single crystals and/or thin deposits can be obtained. In the solid state, the compounds behave as single-component semiconductors with low room temperature conductivity values

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20

Idrees, Sobia, Åsa Pérez-Bercoff, and Richard J. Edwards. "SLiM-Enrich: computational assessment of protein–protein interaction data as a source of domain-motif interactions." PeerJ 6 (October 31, 2018): e5858. http://dx.doi.org/10.7717/peerj.5858.

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Many important cellular processes involve protein–protein interactions (PPIs) mediated by a Short Linear Motif (SLiM) in one protein interacting with a globular domain in another. Despite their significance, these domain-motif interactions (DMIs) are typically low affinity, which makes them challenging to identify by classical experimental approaches, such as affinity pulldown mass spectrometry (AP-MS) and yeast two-hybrid (Y2H). DMIs are generally underrepresented in PPI networks as a result. A number of computational methods now exist to predict SLiMs and/or DMIs from experimental interactio

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21

Kim, Yu C., Joo H. Lee, So H. Kim, and Myung G. Lee. "Effect of CYP3A1(23) Induction on Clarithromycin Pharmacokinetics in Rats with Diabetes Mellitus." Antimicrobial Agents and Chemotherapy 49, no. 6 (2005): 2528–32. http://dx.doi.org/10.1128/aac.49.6.2528-2532.2005.

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ABSTRACT After intravenous and oral administration of clarithromycin at a dose of 20 mg/kg of body weight to rats with diabetes mellitus induced by alloxan (DMIA) and diabetes mellitus induced by streptozotocin (DMIS), the area under the curve values were significantly smaller than those of respective control rats. The in vitro intrinsic clearance values for the disappearance of clarithromycin were significantly faster in both rats with DMIA and rats with DMIS than in control rats. The above data suggested that metabolism of clarithromycin increased in both types of diabetic rat due to an incr

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22

Köller, Wolfram, W. F. Wilcox, J. Barnard, A. L. Jones, and P. G. Braun. "Detection and Quantification of Resistance of Venturia inaequalis Populations to Sterol Demethylation Inhibitors." Phytopathology® 87, no. 2 (1997): 184–90. http://dx.doi.org/10.1094/phyto.1997.87.2.184.

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Monoconidial isolates of Venturia inaequalis were collected in 1990 and 1991 from orchards in New York, Michigan, and Nova Scotia that had never or only sporadically been treated with fungicides acting as sterol demethylation inhibitors (DMIs). Sensitivities of isolates to two representative DMIs (fenarimol and myclobutanil) were determined by a sensitivity test based on the relative growth (RG) of mycelial colonies at one discriminatory dose. Mean isolate sensitivities were not significantly different (P > 0.2) for the majority of the populations tested, and all sensitivity data obtained f

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23

Gao, Yang, Li Gao, Meng Wu, and Chengbin Wang. "Combined Navigation MethodGPS." Xibei Gongye Daxue Xuebao/Journal of Northwestern Polytechnical University 36, no. 2 (2018): 396–402. http://dx.doi.org/10.1051/jnwpu/20183620396.

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According to the characteristics of DMI with high-precision position information, a navigation method combines DMIs with GPS and IMU is proposed in this paper. Firstly, the prototype system architecture is presented and its operational principle is discussed. Secondly, some key technologies are studied, which include integrated organization method of DMIs and road net data, the position method based on DMI matching with real-time image and the federal Kalman filter model with DMI, GPS and IMU. Finally, experimental results show that the proposed method can counteract GPS signal's unlocking pro

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24

Beresford, R. M., P. J. Wright, P. N. Wood, and R. H. Agnew. "Sensitivity of grapevine powdery mildew (Erysiphe necator) to demethylation inhibitor and quinone outside inhibitor fungicides in New Zealand." New Zealand Plant Protection 69 (January 8, 2016): 1–10. http://dx.doi.org/10.30843/nzpp.2016.69.5908.

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Isolates of Erysiphe necator from Hawkes Bay and Marlborough vineyards were tested for sensitivity to three demethylation inhibitor (DMI) fungicides (myclobutanil penconazole and cyproconazole) and one quinone outside inhibitor (QoI) fungicide (trifloxystrobin) Mean colony diameter was determined in a detached grape leaf assay for approximately 20 isolates per vineyard at 1 and 10 mg/litre of each fungicide Resistance to trifloxystrobin was prevalent in Hawkes Bay and Marlborough Mycobutanil resistance was found in both regions but particularly in Marlborough There was some loss of sensitivity

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25

Emerson, Gina, and Hauke Egermann. "Exploring the motivations for building new digital musical instruments." Musicae Scientiae 24, no. 3 (2018): 313–29. http://dx.doi.org/10.1177/1029864918802983.

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Over the past four decades, the number, diversity and complexity of digital musical instruments (DMIs) has increased rapidly. There are very few constraints on DMI design as such systems can be easily reconfigured, offering near limitless flexibility for music-making. Given that new acoustic musical instruments have in many cases been created in response to the limitations of available technologies, what motivates the development of new DMIs? We conducted an interview study with ten designers of new DMIs, in order to explore (a) the motivations electronic musicians may have for wanting to buil

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26

Chen, Shuning, Yunyun Wang, Guido Schnabel та ін. "Inherent Resistance to 14α-Demethylation Inhibitor Fungicides in Colletotrichum truncatum Is Likely Linked to CYP51A and/or CYP51B Gene Variants". Phytopathology® 108, № 11 (2018): 1263–75. http://dx.doi.org/10.1094/phyto-02-18-0054-r.

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Anthracnose disease, caused by Colletotrichum truncatum, affects marketable yield during preharvest production and postharvest storage of fruits and vegetables worldwide. Demethylation inhibitor (DMI) fungicides are among the very few chemical classes of single-site mode of action fungicides that are effective in controlling anthracnose disease. However, some species are inherently resistant to DMIs and more information is needed to understand this phenomenon. Isolates of C. truncatum were collected from the United States and China from peach, soybean, citrus, and begonia and sensitivity to si

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27

Skoropata, Elizabeth, John Nichols, Jong Mok Ok, et al. "Interfacial tuning of chiral magnetic interactions for large topological Hall effects in LaMnO3/SrIrO3 heterostructures." Science Advances 6, no. 27 (2020): eaaz3902. http://dx.doi.org/10.1126/sciadv.aaz3902.

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Chiral interactions in magnetic systems can give rise to rich physics manifested, for example, as nontrivial spin textures. The foremost interaction responsible for chiral magnetism is the Dzyaloshinskii-Moriya interaction (DMI), resulting from inversion symmetry breaking in the presence of strong spin-orbit coupling. However, the atomistic origin of DMIs and their relationship to emergent electrodynamic phenomena, such as topological Hall effect (THE), remain unclear. Here, we investigate the role of interfacial DMIs in 3d–5d transition metal-oxide-based LaMnO3/SrIrO3 superlattices on THE fro

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28

Bordinhão, Jairo, Nadia M. Comerlato, Glaucio B. Ferreira, R. Alan Howie, Carolina X. A. da Silva, and James L. Wardell. "4,5-Bis[(triorganotin)thiolato]-1,3-dithiole-2-thione, (R3Sn)2(dmit), 4,5-bis[(triorganotin)thiolato]-1,3-dithiole-2-one, (R3Sn)2(dmio), compounds: Crystal structures of (cyclohexyl3Sn)2(dmio), (Ph3Sn)2(dmit) and (Ph3Sn)2(dmio)." Journal of Organometallic Chemistry 691, no. 8 (2006): 1598–605. http://dx.doi.org/10.1016/j.jorganchem.2005.10.035.

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Tasheva, E. S., and D. J. Roufa. "Densely methylated DNA islands in mammalian chromosomal replication origins." Molecular and Cellular Biology 14, no. 9 (1994): 5636–44. http://dx.doi.org/10.1128/mcb.14.9.5636.

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Densely methylated DNA sequence islands, designated DMIs, have been observed in two Chinese hamster cell chromosomal replication origins by using a PCR-based chemical method of detection. One of the origins, oriS14, is located within or adjacent to the coding sequence for ribosomal protein S14 on chromosome 2q, and the other, ori-beta, is approximately 17 kbp downstream of the dhfr (dihydrofolic acid reductase) locus on chromosome 2p. The DMI in oriS14 is 127 bp long, and the DMI in ori-beta is 516 bp long. Both DMIs are bilaterally methylated (i.e., all dCs are modified to 5-methyl dC) only i

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Tasheva, E. S., and D. J. Roufa. "Densely methylated DNA islands in mammalian chromosomal replication origins." Molecular and Cellular Biology 14, no. 9 (1994): 5636–44. http://dx.doi.org/10.1128/mcb.14.9.5636-5644.1994.

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Densely methylated DNA sequence islands, designated DMIs, have been observed in two Chinese hamster cell chromosomal replication origins by using a PCR-based chemical method of detection. One of the origins, oriS14, is located within or adjacent to the coding sequence for ribosomal protein S14 on chromosome 2q, and the other, ori-beta, is approximately 17 kbp downstream of the dhfr (dihydrofolic acid reductase) locus on chromosome 2p. The DMI in oriS14 is 127 bp long, and the DMI in ori-beta is 516 bp long. Both DMIs are bilaterally methylated (i.e., all dCs are modified to 5-methyl dC) only i

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Bolton, Melvin D., Keshav Birla, Viviana Rivera-Varas, Kurt D. Rudolph, and Gary A. Secor. "Characterization of CbCyp51 from Field Isolates of Cercospora beticola." Phytopathology® 102, no. 3 (2012): 298–305. http://dx.doi.org/10.1094/phyto-07-11-0212.

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The hemibiotrophic fungus Cercospora beticola causes leaf spot of sugar beet. Leaf spot control measures include the application of sterol demethylation inhibitor (DMI) fungicides. However, reduced sensitivity to DMIs has been reported recently in the Red River Valley sugar beet-growing region of North Dakota and Minnesota. Here, we report the cloning and molecular characterization of CbCyp51, which encodes the DMI target enzyme sterol P450 14α-demethylase in C. beticola. CbCyp51 is a 1,632-bp intron-free gene with obvious homology to other fungal Cyp51 genes and is present as a single copy in

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32

Chen, Shuning, Mengjun Hu, Guido Schnabel, Daibin Yang, Xiaojing Yan, and Huizhu Yuan. "Paralogous CYP51 Genes of Colletotrichum spp. Mediate Differential Sensitivity to Sterol Demethylation Inhibitors." Phytopathology® 110, no. 3 (2020): 615–25. http://dx.doi.org/10.1094/phyto-10-19-0385-r.

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Colletotrichum spp. isolates contain two paralogous CYP51 genes that encode sterol 14-demethylase enzymes; however, their role in sensitivity to demethylation inhibitor (DMI) fungicides is yet to be determined. In this study, each of the two genes from Colletotrichum fioriniae and C. nymphaeae was able to rescue the function of CYP51 in the yeast Saccharomyces cerevisiae, demonstrating their independent function. Deletion of CYP51A led to increased sensitivity to propiconazole, diniconazole, prothioconazole, cyproconazole, epoxiconazole, flutriafol, prochloraz, and difenoconazole in C. fiorini

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Nagao, Kazuhiko, Keitarou Suzuki, Satomi Hamada, Shoji Yahara, Ryuji Yamamura, and Masaru Uyeda. "1513-DMIa and 1513-DMIb, Dna Methyltransferase Inhibitors Produced byStreptomycesSp. Strain No. 1513." Journal of Enzyme Inhibition 13, no. 2 (1998): 135–46. http://dx.doi.org/10.3109/14756369809035832.

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Ortiz-Berrocal, Marlene, Luis Lozano, Alejandro Sanchez-Flores, Noreide Nava, Georgina Hernández, and Pallavolu M. Reddy. "Expression in rice of an autoactive variant of Medicago truncatula DMI3, the Ca+2/calmodulin-dependent protein kinase from the common symbiotic pathway modifies root transcriptome and improves mycorrhizal colonization." Plant Biotechnology Reports 11, no. 5 (2017): 271–87. http://dx.doi.org/10.1007/s11816-017-0449-4.

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Costa, Willams De Lima, Daniel Filgueira, Luca Ananias, Ricardo Barioni, Lucas Silva Figueiredo, and Veronica Teichrieb. "Songverse: a music-loop authoring tool based on Virtual Reality." Journal on Interactive Systems 11, no. 1 (2020): 57–65. http://dx.doi.org/10.5753/jis.2020.749.

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We can define Digital Musical Instruments (DMIs) as hardware-software solutions that are interactive and crafted to output sound according to users' input. DMIs are well known to unleash users' creativity but also to allow different and innovative experiences for the creation process, for example, smoothing the learning curve towards musical concepts such as rhythm and composition. On the other hand, Virtual Reality (VR) allows users to explore spatial interfaces in a natural and limitless way, which shows potential synergy towards the rise of new DMIs. In this paper, we introduce Songverse, a

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Faichney, G. J., and S. G. Gherardi. "Relationships between organic-matter digestibility, dry-matter intake and solute mean retention times in sheep given a ground and pelleted diet." Journal of Agricultural Science 106, no. 2 (1986): 219–22. http://dx.doi.org/10.1017/s0021859600063796.

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SUMMARYThe relationships between organic-matter digestibility (OMD), dry-matter intake (DMI) and the mean retention time (MRT) of unabsorbed solutes in the gastrointestinal tract were examined using six fistulated, cross-bred, castrate male sheep. Measurements were made on each sheep at two different DMIs within the range 28–81 g D.m./(day. kg0·75). There were negative, curvilinear relationships between MRTs (both rumen and total) and DMI and positive, curvilinear relationships between OMD and MRTs. As a consequence, there was a negative, rectilinear relationship between OMD and DMI. OMD decli

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Arduim, Gisele da Silva, Erlei Melo Reis, Amarilis Labes Barcellos, and Camila Turra. "In vivo sensitivity reduction of Puccinia triticina races, causal agent of wheat leaf rust, to DMI and QoI fungicides." Summa Phytopathologica 38, no. 4 (2012): 306–11. http://dx.doi.org/10.1590/s0100-54052012000400006.

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Experiments were carried out to determine in vivo the IC50 and the IC90 for demethylation-inhibitor fungicides (DMIs, triazoles) and quinone outside inhibitors (QoIs, strobilurins) to the five most frequent races of Puccinia triticina in 2007 growing season in Southern Brazil. The tests were done in a greenhouse with wheat seedlings. DMI fungicides were tested at the concentrations, in mg/L, 0.0; 0.02; 0.2; 2.0; 20.0; 100.0 and 200.0, and QoIs at the concentrations 0.0; 0.0001; 0.001; 0.01; 0.1; 1 and 10.0 mg of active ingredient/L water. Fungicides were preventively applied at 24 hours before

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Köller, Wolfram, and W. F. Wilcox. "Evaluation of Tactics for Managing Resistance of Venturia inaequalis to Sterol Demethylation Inhibitors." Plant Disease 83, no. 9 (1999): 857–63. http://dx.doi.org/10.1094/pdis.1999.83.9.857.

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The impact on the selection and control of subpopulations of V. inaequalis resistant to the sterol demethylation inhibitor (DMI) fenarimol or to dodine were evaluated with respect to several tactics of apple scab control. Experiments were conducted in an experimental orchard with elevated levels of DMI and dodine resistance over a period of three consecutive seasons. The DMI-resistant subpopulation was poorly (14%) controlled at a fenarimol rate of 15 mg/liter (sprayed to run-off), whereas control was significantly improved (54%) at twice that rate. Mancozeb mixed with the low rate of fenarimo

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Meyers, Emily, Consuelo Arellano, and Christina Cowger. "Sensitivity of the U.S. Blumeria graminis f. sp. tritici Population to Demethylation Inhibitor Fungicides." Plant Disease 103, no. 12 (2019): 3108–16. http://dx.doi.org/10.1094/pdis-04-19-0715-re.

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Wheat powdery mildew, caused by Blumeria graminis f. sp. tritici, is managed in the United States with cultivar resistance and foliar fungicides. Despite high levels of fungicide sensitivity in other cereal mildew populations, fungicide sensitivity of U.S. B. graminis f. sp. tritici has never been evaluated. Almost 400 B. graminis f. sp. tritici isolates were collected from 15 U.S. states over 2 years and phenotyped for sensitivity to two widely used demethylation inhibitor (DMI) fungicides, tebuconazole and prothioconazole. A large range of sensitivity to both DMIs was observed, with more ins

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Dutra, Pamela Suellen Salvador, Paulo S. F. Lichtemberg, Maria Bernat Martinez, Themis J. Michailides, and Louise Larissa May De Mio. "Cross-Resistance Among Demethylation Inhibitor Fungicides With Brazilian Monilinia fructicola Isolates as a Foundation to Discuss Brown Rot Control in Stone Fruit." Plant Disease 104, no. 11 (2020): 2843–50. http://dx.doi.org/10.1094/pdis-04-20-0714-re.

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Despite the resistance problems in Monilinia fructicola, demethylation inhibitor fungicides (DMIs) are still effective for the disease management of brown rot in commercial stone fruit orchards in Brazil. This study aims to investigate the sensitivity of M. fructicola isolates and efficiency of DMIs to reduce brown rot. A set of 93 isolates collected from Brazilian commercial orchards were tested for their sensitivities to tebuconazole, propiconazole, prothioconazole, and myclobutanil. The isolates were analyzed separately according to the presence or absence of the G461S mutation in MfCYP51 g

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Vicente, R., J. Ribas, C. Zanchini, et al. "Molecular and Crystal Structure, and EPR Studies of Tetraphenylarsonium [Bis-(1,3-dithia-2-one-4,5-dithiolato)-nickelate], (AsPh4)[Ni(dmid)2]." Zeitschrift für Naturforschung B 43, no. 9 (1988): 1137–43. http://dx.doi.org/10.1515/znb-1988-0909.

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AbstractThe crystal structure of (AsPh4)[Ni(dmid)2 (dmid2- = 1,3-dithia-2-one-4,5-dithiolato) has been determined by X-ray diffraction studies: crystals are monoclinic, space group P21/n a = 14.724(2), b = 14.305(5), c = 15.570(3) Å, β = 92.20(1)°, V = 3277 Å3 , ᵨx = 1.63 g cm-3 for Z = 4, final conventional agreement indices R = 0.038 and Rw = 0.049 for 2115 unique, observed reflections and 211 variable parameters. The asymmetric unit contains one (AsPh4)+ cation and one [Ni(dmid)2] anion, both in general positions. The anions are isolated from each other by the bulky cations. The [Ni(dmid)2]

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Beresford, R. M., P. J. Wright, P. N. Wood, and N. M. Park. "Sensitivity of Venturia inaequalis to myclobutanil penconazole and dodine in relation to fungicide use in Hawkes Bay apple orchards." New Zealand Plant Protection 65 (January 8, 2012): 106–13. http://dx.doi.org/10.30843/nzpp.2012.65.5396.

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A survey of Integrated Fruit Production and organic apple orchards in Hawkes Bay in 201011 investigated sensitivity of Venturia inaequalis isolates to demethylation inhibitor (DMI) and dodine fungicides EC50 values from mycelial growth assays for two DMIs showed continued loss of sensitivity since the 1990s Sensitivity was lower in orchards where DMI usage exceeded resistance management guidelines The most DMIsensitive isolates were found in one organic orchard Plant inoculations showed that black spot control of myclobutanilresistant V inaequalis strains by one application of myclobutanil was

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Wang, Xiao, and Haja N. Kadarmideen. "Characterization of Global DNA Methylation in Different Gene Regions Reveals Candidate Biomarkers in Pigs with High and Low Levels of Boar Taint." Veterinary Sciences 7, no. 2 (2020): 77. http://dx.doi.org/10.3390/vetsci7020077.

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DNA methylation of different gene components, including different exons and introns, or different lengths of exons and introns is associated with differences in gene expression. To investigate the methylation of porcine gene components associated with the boar taint (BT) trait, this study used reduced representation bisulfite sequencing (RRBS) data from nine porcine testis samples in three BT groups (low, medium and high BT). The results showed that the methylation levels of the first exons and first introns were lower than those of the other exons and introns. The first exons/introns of CpG i

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Nakaune, Ryoji, Kiichi Adachi, Osamu Nawata, Masamitsu Tomiyama, Katsumi Akutsu, and Tadaaki Hibi. "A Novel ATP-Binding Cassette Transporter Involved in Multidrug Resistance in the Phytopathogenic FungusPenicillium digitatum." Applied and Environmental Microbiology 64, no. 10 (1998): 3983–88. http://dx.doi.org/10.1128/aem.64.10.3983-3988.1998.

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ABSTRACT Demethylation inhibitor (DMI)-resistant strains of the plant pathogenic fungus Penicillium digitatum were shown to be simultaneously resistant to cycloheximide, 4-nitroquinoline-N-oxide (4NQO), and acriflavine. APMR1 (Penicillium multidrug resistance) gene encoding an ATP-binding cassette (ABC) transporter (P-glycoprotein) was cloned from a genomic DNA library of a DMI-resistant strain (LC2) ofPenicillium digitatum by heterologous hybridization with a DNA fragment containing an ABC-encoding region from Botrytis cinerea. Sequence analysis revealed significant amino acid homology to the

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Beresford, R. M., P. J. Wright, P. N. Wood, N. M. Park, N. J. Larsen, and B. M. Fisher. "Resistance of Venturia inaequalis to demethylation inhibitor and dodine fungicides in four New Zealand applegrowing regions." New Zealand Plant Protection 66 (January 8, 2013): 274–83. http://dx.doi.org/10.30843/nzpp.2013.66.5654.

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A survey of 41 apple orchards in Hawkes Bay (25) Nelson (7) Otago (4) and Waikato (5) provided 796 isolates of Venturia inaequalis (black spot or scab) which were tested using an agar plate assay for sensitivity to two demethylation inhibitor (DMI) fungicides (myclobutanil and penconazole) and to dodine Each fungicide was used at two concentrations to distinguish between highly sensitive sensitive and resistant isolates Sensitivity to DMIs in all regions was lower than baseline sensitivity in previous studies particularly for myclobutanil Waikato showed significantly lower DMI sensitivity than

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Hayashi, Keisuke, Henk-jan Schoonbeek, and Maarten A. De Waard. "Bcmfs1, a Novel Major Facilitator Superfamily Transporter from Botrytis cinerea, Provides Tolerance towards the Natural Toxic Compounds Camptothecin and Cercosporin and towards Fungicides." Applied and Environmental Microbiology 68, no. 10 (2002): 4996–5004. http://dx.doi.org/10.1128/aem.68.10.4996-5004.2002.

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ABSTRACT Bcmfs1, a novel major facilitator superfamily gene from Botrytis cinerea, was cloned, and replacement and overexpression mutants were constructed to study its function. Replacement mutants showed increased sensitivity to the natural toxic compounds camptothecin and cercosporin, produced by the plant Camptotheca acuminata and the plant pathogenic fungus Cercospora kikuchii, respectively. Overexpression mutants displayed decreased sensitivity to these compounds and to structurally unrelated fungicides, such as sterol demethylation inhibitors (DMIs). A double-replacement mutant of Bcmfs1

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Ishii, Hideo, Hans Jorgen Cools, Kumiko Nishimura, Lorenzo Borghi, Kenji Kikuhara, and Yuichi Yamaoka. "DMI-Fungicide Resistance in Venturia nashicola, the Causal Agent of Asian Pear Scab—How Reliable Are Mycelial Growth Tests in Culture?" Microorganisms 9, no. 7 (2021): 1377. http://dx.doi.org/10.3390/microorganisms9071377.

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Scab, caused by Venturia nashicola, is among the most serious diseases of Asian pears and control of this disease largely relies on sterol demethylation inhibitor (DMI) fungicides. However, pear growers have complained about field performance of DMIs since the mid-2000s. In this study, to evaluate pathogen sensitivity, mycelial growth tests and inoculation tests were conducted using DMI-amended culture medium and fungicide-sprayed potted pear trees, respectively. Results confirmed distribution of isolates resistant to fenarimol, hexaconazole, and difenoconazole in the field populations. Import

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Kunz, Stefan, Holger Deising, and Kurt Mendgen. "Acquisition of Resistance to Sterol Demethylation Inhibitors by Populations of Venturia inaequalis." Phytopathology® 87, no. 12 (1997): 1272–78. http://dx.doi.org/10.1094/phyto.1997.87.12.1272.

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Acquisition of resistance to sterol demethylation inhibitors (DMIs) by populations of Venturia inaequalis was investigated using a microscopical method developed by C. Siebels and K. Mendgen. Microscopical analysis of conidiophore formation enabled the earlier detection of resistance and a clearer distinction between DMI-resistant and DMI-sensitive populations than other in vivo methods commonly used to analyze inhibitory effects of fungicides. In addition, because observations were made on the level of individuals, quantitative measures of the composition of conidial populations were obtained

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Yin, Y., X. Liu, B. Li, and Z. Ma. "Characterization of Sterol Demethylation Inhibitor-Resistant Isolates of Fusarium asiaticum and F. graminearum Collected from Wheat in China." Phytopathology® 99, no. 5 (2009): 487–97. http://dx.doi.org/10.1094/phyto-99-5-0487.

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Fusarium asiaticum and F. graminearum are the primary causal agents of Fusarium head blight (FHB) of wheat in China. In this study, sensitivities of 159 F. asiaticum and F. graminearum isolates to a benzimidazole fungicide carbendazim (MBC) and to sterol demethylation inhibitors (DMIs) tebuconazole and prochloraz were determined. Among the 159 isolates, 9 were resistant to MBC and designated as MBC-R isolates. Three showed resistance to tebuconazole and prochloraz and designated as DMI-R isolates. There was no cross-resistance between MBC and DMI. Genetic analysis by microsatellite-primed poly

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Lyon, Eric, R. Benjamin Knapp, and Gascia Ouzounian. "Compositional and Performance Mapping in Computer Chamber Music: A Case Study." Computer Music Journal 38, no. 3 (2014): 64–75. http://dx.doi.org/10.1162/comj_a_00257.

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The mapping problem is inherent to digital musical instruments (DMIs), which require, at the very least, an association between physical gestures and digital synthesis algorithms to transform human bodily performance into sound. This article considers the DMI mapping problem in the context of the creation and performance of a heterogeneous computer chamber music piece, a trio for violin, biosensors, and computer. Our discussion situates the DMI mapping problem within the broader set of interdependent musical interaction issues that surfaced during the composition and rehearsal of the trio. Thr

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