Dissertations / Theses on the topic 'DMLS'
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Jack, William Josiah. "A Six Sigma Approach to Implementing Conformal Cooling on Existing Processes in Injection Molding." OpenSIUC, 2017. https://opensiuc.lib.siu.edu/theses/2214.
Full textMordenti, Eugenio. "Comportamento a fatica dell’acciaio Maraging MS1 prodotto tramite DMLS: influenza della posizione nella camera." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amslaurea.unibo.it/16511/.
Full textRamosoeu, Makhabo Khabiso Ellen. "Characterisation and static behaviour of the DMLS Ti-6AI-4V for Bio-medical applications." Thesis, Bloemfontein: Central University of Technology, Free State, 2015. http://hdl.handle.net/11462/275.
Full textThe Centre for Rapid Prototyping and Manufacturing (CRPM) at the Central University of Technology, Free State (CUT) manufactures implants using Electro Optical Systems (EOS) titanium Ti-6Al-4V alloy powder (further referred to as EOS Ti64 powder) by means of Direct Metal Laser Sintering (DMLS) process on the EOSINT M 270 machine. For this reason, there is a need to characterise and acquire knowledge of the basic properties of direct metal laser sintered EOS titanium Ti-6Al-4V alloy samples (further referred to as DMLS Ti64 samples) under static tensile loading in order to provide the CRPM with engineering design data. The first objective of this Master’s study is to acquire the characteristics of EOS Ti64 powder in order to ascertain its suitability in the DMLS process. Secondly, the study aims to assess tensile properties and elastic constants of DMLS Ti64 samples produced from the set process parameters of EOSINT M 270 machine. Thirdly, it is to investigate microstructures of DMLS Ti64 samples subjected to different heat treatment techniques which will eventually assist in the determination of a suitable heat treatment technique that will yield higher ductility. Finally, the study aims to validate the static behaviour of DMLS Ti64 samples subjected to the static tensile loading up to a yield point in order to determine failure due to yielding. The samples were manufactured at CRPM Bloemfontein. The metallographic examinations, heat treatment and the determination of mechanical properties were done at the CSIR in Pretoria. Optical Microscope (OM) and Scanning Electron Microscope (SEM) were used to determine microstructures of DMLS Ti64 samples while Energy Dispersive X-Ray (EDX) analyses were performed using SEM. The samples were heat treated at temperatures of 700, 1000 and 1100°C respectively, and subsequently either cooled with the furnace, air or were water quenched. The mechanical property tests included tensile, hardness and determination of elastic constants. The static behaviour of DMLS Ti64 samples under static tensile load up to a yield point was predicted and verified using ABAQUSTM Finite Element Analysis (FEA). The stress-strain curves from ABAQUSTM were interpreted using MDSolid program. The point of interest was Von Mises yield stress at 0.2% offset, in order to determine failure due to yielding. EOS Ti64 powder particles were spherical in shape and the alpha and alpha+beta phases were identified. As-laser sintered samples possess a very fine and uniform alpha case with islands of martensitic plates; samples were brittle and showed low levels of ductility with an average elongation of 2.6% and an area reduction of 3.51%. Ultrasonic test results showed that DMLS Ti64 samples have Young’s modulus of 115 GPa, Shear modulus of 43 GP, a bulk modulus of 109 GPa and Poisson’s ratio of 0,323 while the density was 4.4 g/cm3. Slow cooling of DMLS Ti64 samples from 1000 and 1100oC resulted in a microstructure constituted more by the alpha phase of lower hardness than those from 700oC and as-laser sintered samples. High hardness was obtained by water quenching. The water quenched samples showed martensitic transformation and high hardness when compared to furnace cooled samples. Beta annealing tailored a microstructure of as-laser sintered samples into a lamellar structure with different lath sizes as per cooling rate. Beta annealing improved ductility levels up to 12.67% elongation for samples furnace cooled for 4 hours and even higher to 18.11% for samples furnace cooled for 34 hours, while area reduction increased to 25.94% and 33.39%, respectively. Beta annealing conversely reduced yield strength by 19.89% and ultimate tensile strength was reduced by 23.66%. The calculated maximum Von Mises stresses found were similar to the FEA interpreted results. The average percentage error, without the stress concentration factor, was approximately 8.29%; with the stress concentration factor included, it was 0.07%. The small reaction forces induced in both x-axis and z-axis contributed to this error of 0.07% between the calculations and ABAQUSTM FEA results. Samples that were not heat treated fell outside the Von Mises criterion and failed due to yielding. This justified the brittleness found in the tensile test results where elongation and area reduction were 2.6% and 3.51% respectively. However, all samples that were heat treated fell within the Von Mises criterion. The objectives of this study were achieved; the mechanical properties were similar to those of standard specification for wrought annealed Ti-6Al-4V alloy for surgical implant applications and EOS GmbH manufacturer’s material data sheet. DMLS Ti64 samples must be beta annealed in order to attain higher levels of ductility. A recommendation was made to further investigate the effect of heat treatment on the other mechanical properties. Furthermore, detailed results of basic properties of DMLS Ti64 samples are provided in the appendices in chart format and were written on a CD disc.
Jaime, Gustavo Carneiro. "Análise comparativa da resistência à corrosão eletroquímica da liga de Ti-6Al-4V e do aço inoxidável AISI316L obtidas por manufatura aditiva visando aplicações biomédicas /." Ilha Solteira, 2017. http://hdl.handle.net/11449/152091.
Full textResumo: A procura por materiais, com compatibilidade e funcionalidade biológicas, que possam melhorar a qualidade da vida humana é constante, além da busca de processos de fabricação que atendam às necessidades de manufatura de artefatos de geometria complexa. Os artefatos de aço inoxidável são utilizados por possuírem uma boa biocompatibilidade, baixo custo de produção, mas podem liberar íons como o cobalto, que é carcinogênico. O uso de Ligas de titânio é uma boa alternativa, já que possuem uma maior resistência à corrosão e boa resposta biológica, porém, seu custo é muito elevado. Considerando esses aspectos, o presente trabalho foi realizado buscando estudar, comparativamente, as características de microdureza, microdesgaste e resistência à corrosão de artefatos manufaturados para aplicações biomédicas, aproveitando as características mecânicas da liga de aço inoxidável AISI316L, usado como substrato, com as características eletroquímicas apresentadas pela liga de titânio Ti-6Al-4V, usado como material de tratamento de superfície. A sinterização direta dos metais por laser (DMLS) foi o processo de manufatura escolhido por apresentar as características de fabricação desejadas. Os ensaios realizados foram o de microdureza Vickers, ensaio de desgaste microadesivo por esfera rotativa fixa (esfera-fixa) e para o comparativo da resistência à corrosão eletroquímica foram produzidas curvas de polarização potenciodinâmicas que forneceram os seguintes parâmetros: o potencial de corrosão, a... (Resumo completo, clicar acesso eletrônico abaixo)
Mestre
Capelli, Alessandro. "Effetto della posizione in camera sulla resistenza a fatica dell'acciaio Maraging MS1 prodotto tramite DMLS." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amslaurea.unibo.it/17419/.
Full textRighini, Nicola. "Prove di fatica a flessione rotante su provini in acciaio inossidabile PH1 ottenuti tramite DMLS." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2019.
Find full textSekerka, Vít. "Výroba dílů technologií DMLS a jejich porovnání s jinými konvenčními technologiemi z hlediska ekonomické náročnosti." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2011. http://www.nusl.cz/ntk/nusl-229969.
Full textGhirardi, Lorenzo. "Comportamento a fatica di provini in acciaio inossidabile realizzati tramite DMLS con diverse direzioni di accrescimento." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2016. http://amslaurea.unibo.it/10665/.
Full textRavaioli, Irma. "Resistenza a fatica di pezzi in acciaio realizzati per DMLS a seconda di diversi parametri costruttivi." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2016.
Find full textPiraccini, Giorgio. "Prove sperimentali di fatica a flessione rotante su provini in acciaio inossidabile PH1 ottenuti per DMLS." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2019.
Find full textLanger, H. J., and M. Shellabear. "Recent e-Manufacturing solutions developed by EOS." Journal for New Generation Sciences, Vol 4, Issue 1: Central University of Technology, Free State, Bloemfontein, 2006. http://hdl.handle.net/11462/492.
Full texte-Manufacturing means the fast, flexible and cost-effective production of parts directly from electronic data, which can include rapid prototyping, rapid tooling, (spare) parts on demand etc. Especially interesting is the direct manufacture of enduse parts. In this paper, recent case studies will be presented showing commercial e-Manufacturing projects including small production batches and mass customized series production from various industrial branches. The paper also discusses the relevance of several recent technological innovations in laser-sintering for e- Manufacturing, especially how increasing the productivity of machines and process chains has increased the range of applications which are cost-effective using lasersintering.
Case studies include:
- small series production (up to a few thousand p.a.) of products
- production of customized (one-off) products
- mass production of customer-specific (mass customized) products
- optimized tooling concepts for production of up to millions of products
Patibandla, Aditya Ramamurthy. "Effect of Process Parameters on Surface Roughness and Porosity of Direct Metal Laser Sintered Metals." University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1544691813554763.
Full textMagnani, Alessandro. "Effetto del trattamento termico e della lavorazione meccanica sulla resistenza a fatica dell’acciaio Maraging Steel MS1 accresciuto tramite DMLS." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2017.
Find full textTondini, Fabio. "Resistenza a fatica dell’acciaio Maraging MS1 prodotto tramite DMLS: effetto dei trattamenti post-processo e della posizione in camera." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amslaurea.unibo.it/16556/.
Full textBigazzi, Elena. "Effetto dello spessore di sovrametallo rimosso nella lavorazione meccanica sulla resistenza a fatica dell’acciaio Maraging Steel MS1 accresciuto tramite DMLS." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2017.
Find full textLonghitano, Guilherme Arthur 2015. "Estudo de tratamentos térmicos e acabamentos de superfície na liga Ti-6Al-4V produzida via DMLS para aplicação em implantes." [s.n.], 2016. http://repositorio.unicamp.br/jspui/handle/REPOSIP/265833.
Full textDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Mecânica
Made available in DSpace on 2018-08-26T21:12:43Z (GMT). No. of bitstreams: 1 Longhitano_GuilhermeArthur_2015_M.pdf: 10352364 bytes, checksum: 6157c8c85d67a80202c0078ff2bd5901 (MD5) Previous issue date: 2016
Resumo: No presente trabalho, a liga de titânio Ti-6Al-4V, empregada em implantes ortopédicos permanentes ou temporários devido à sua biocompatibilidade, foi produzida a partir da manufatura aditiva utilizando o processo de Sinterização Direta de Metais por Laser (DMLS). O material foi submetido a diferentes tratamentos térmicos com o intuito de modificar suas propriedades mecânicas, e a acabamentos de jateamento, ataque químico e polimento eletroquímico para analisar os efeitos dos mesmos no acabamento de superfície. As modificações resultantes após os tratamentos térmicos e acabamentos de superfície foram analisadas por microscopia óptica, microscopia eletrônica de varredura, difração de raios-X, medidas de rugosidade e massa, microdureza Vickers, e ensaios de tração e compressão. No estudo de acabamentos de superfície, o menor valor de rugosidade foi obtido após as etapas de jateamento e ataque químico combinadas. O acabamento de jateamento é responsável por deixar uma superfície com rugosidade uniforme, enquanto o ataque químico é responsável pela limpeza da superfície e redução da rugosidade. As amostras foram submetidas aos tratamentos térmicos nas temperaturas de 850 ºC, 950 ºC e 1050 ºC durante uma hora com resfriamento em forno. Foi constatado que quanto maior a temperatura empregada, maior é a ductilidade do material e, por outro lado, menor é a resistência mecânica. Tal fato ocorreu devido à maior nucleação e crescimento da fases 'alfa' e 'beta' no material, que apresentava inicialmente uma estrutura constituída por martensita hexagonal ('alfa'). A condição de tratamento térmico a 950 ºC foi a que apresentou a melhor relação de propriedades mecânicas, satisfazendo os requerimentos da norma ASTM F136 para a utilização da liga Ti-6Al-4V em implantes
Abstract: In this study, the Ti-6Al-4V titanium alloy, used in permanent or temporary orthopedic implants due to its biocompatibility, was produced by additive manufacturing using the Direct Metal Laser Sintering (DMLS) process. The material was subjected to different heat treatments in order to modify their mechanical properties, and to the surface finishes of blasting, chemical etching and electropolishing to analyze their effects on surface finish. The resulting changes after the heat treatments and surface finishes were analyzed by optical microscopy, scanning electron microscopy, X-ray diffraction, roughness and mass measurements, Vickers microhardness, and tensile and compression tests. In surface finishes study, the lowest roughness value was obtained after the combined steps of blasting and chemical etching. The blasting finish is responsible for leaving a surface with uniform roughness, while the chemical etching is responsible for cleaning the surface and reducing roughness. The samples were subjected to heat treatments at temperatures of 850 °C, 950 °C and 1050 °C for one hour followed by furnace cooling. It has been found that the higher the temperature employed, the higher the ductility of the material and, on the other hand, the lower the mechanical strength. This happened due to increased nucleation and growth of 'alfa' and 'beta' phases in the material, which initially had a structure made of hexagonal martensite ('alfa'). The condition of heat treatment at 950 ° C showed the best relation of mechanical properties, meeting the requirements of ASTM F136 for the use of Ti-6Al-4V alloy in implants
Mestrado
Materiais e Processos de Fabricação
Mestre em Engenharia Mecânica
KRISHNAN, MANICKAVASAGAM. "Investigation of material and mechanical properties of Al alloy and Al based MMC parts produced by DMLS for industrial application." Doctoral thesis, Politecnico di Torino, 2014. http://hdl.handle.net/11583/2530290.
Full textPozzi, Francesco. "Direct metal laser sintering of steel with high vanadium content." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amslaurea.unibo.it/13548/.
Full textGregolin, Rafael Ferreira [UNESP]. "Desenvolvimento, comportamento mecânico e microestrutural de uma prótese mandibular em liga de titânio produzida por sinterização direta a laser de metal (DMLS)." Universidade Estadual Paulista (UNESP), 2013. http://hdl.handle.net/11449/94477.
Full textA prototipagem rápida está sendo utilizada em diversas áreas do conhecimento humano para auxiliar no estudo e muitas vezes na própria fabricação do componente usual. Atualmente, com o avanço de softwares, pode-se criar com facilidade imagens tridimensionais, ou mesmo, capturar essas imagens de equipamentos como a tomografia computadorizada e a ressonância magnética. Consegue-se reproduzir qualquer parte do corpo humano com grande perfeição e isso é utilizado na fabricação de implantes, scaffolds (arcabouços – engenharia de tecidos), materiais de auxílio e preparação em cirurgias (biomodelos). Os principais materiais utilizados na fabricação de implantes hoje são: o titânio puro, as ligas de titânio, o aço inoxidável, o polietileno, o PMMA, as ligas de cobalto-cromo e as cerâmicas. Este trabalho se propõe a fazer: um estudo mecânico e microestrutural da liga Ti-6Al-4V obtida por prototipagem rápida no processo de sinterização direta a laser de metais (DMLS) e compará-la com a liga Ti-6Al-4V produzida por processos convencionais de conformação (trefilação). Além disso, pretende realizar o desenvolvimento de uma placa condilar personalizada utilizada para patologias de distúrbios de ATM (articulação têmporo-mandibular), avaliando sua geometria pelo software ANSYS®, com o apoio da tomografia computadoriza e do software de construção de imagens tridimensionais INVESALIUS®
Rapid prototyping is being used in various areas of human knowledge to assist in the study and often in the usual component manufacturing. Today, with the advancement of software, you can easily create three-dimensional images, or even, capture these images of equipment such as computed tomography and magnetic resonance imaging. You able to reproduce any part of the human body with great perfection and it’s used in the manufacture of implants, scaffolds (tissue engineering), material aid and preparation for surgery (biomodels). The main materials used in the manufacture of implants today are: pure titanium, titanium alloys, stainless steel, polyethylene, PMMA, the cobalt-chromium alloys and ceramics. This paper proposes to do: mechanical and microstructural studies of alloy Ti-6Al-4V obtained by rapid prototyping process in direct metal laser sintering (DMLS) and compare it with the Ti-6Al-4V alloy produced by conventional forming process (wiredrawing). Also, make the development of a custom condylar plate used for diseases of TMJ (temporomandibular joint) disorders, assessing its geometry by ANSYS® software with the help of computerized tomography and the software to build three-dimensional images INVESALIUS®
Gregolin, Rafael Ferreira. "Desenvolvimento, comportamento mecânico e microestrutural de uma prótese mandibular em liga de titânio produzida por sinterização direta a laser de metal (DMLS) /." Ilha Solteira, 2013. http://hdl.handle.net/11449/94477.
Full textBanca: João Antonio Pereira
Banca: Cecilia Amelia de Carvalho Zavaglia
Resumo: A prototipagem rápida está sendo utilizada em diversas áreas do conhecimento humano para auxiliar no estudo e muitas vezes na própria fabricação do componente usual. Atualmente, com o avanço de softwares, pode-se criar com facilidade imagens tridimensionais, ou mesmo, capturar essas imagens de equipamentos como a tomografia computadorizada e a ressonância magnética. Consegue-se reproduzir qualquer parte do corpo humano com grande perfeição e isso é utilizado na fabricação de implantes, scaffolds (arcabouços - engenharia de tecidos), materiais de auxílio e preparação em cirurgias (biomodelos). Os principais materiais utilizados na fabricação de implantes hoje são: o titânio puro, as ligas de titânio, o aço inoxidável, o polietileno, o PMMA, as ligas de cobalto-cromo e as cerâmicas. Este trabalho se propõe a fazer: um estudo mecânico e microestrutural da liga Ti-6Al-4V obtida por prototipagem rápida no processo de sinterização direta a laser de metais (DMLS) e compará-la com a liga Ti-6Al-4V produzida por processos convencionais de conformação (trefilação). Além disso, pretende realizar o desenvolvimento de uma placa condilar personalizada utilizada para patologias de distúrbios de ATM (articulação têmporo-mandibular), avaliando sua geometria pelo software ANSYS®, com o apoio da tomografia computadoriza e do software de construção de imagens tridimensionais INVESALIUS®
Abstract: Rapid prototyping is being used in various areas of human knowledge to assist in the study and often in the usual component manufacturing. Today, with the advancement of software, you can easily create three-dimensional images, or even, capture these images of equipment such as computed tomography and magnetic resonance imaging. You able to reproduce any part of the human body with great perfection and it's used in the manufacture of implants, scaffolds (tissue engineering), material aid and preparation for surgery (biomodels). The main materials used in the manufacture of implants today are: pure titanium, titanium alloys, stainless steel, polyethylene, PMMA, the cobalt-chromium alloys and ceramics. This paper proposes to do: mechanical and microstructural studies of alloy Ti-6Al-4V obtained by rapid prototyping process in direct metal laser sintering (DMLS) and compare it with the Ti-6Al-4V alloy produced by conventional forming process (wiredrawing). Also, make the development of a custom condylar plate used for diseases of TMJ (temporomandibular joint) disorders, assessing its geometry by ANSYS® software with the help of computerized tomography and the software to build three-dimensional images INVESALIUS®
Mestre
Britto, Carlos Eduardo Silva. "Influência da orientação de prototipagem no comportamento mecânico da liga Ti-6Al-4V produzida por sinterização direta de metal por laser (DMLS) /." Ilha Solteira, 2015. http://hdl.handle.net/11449/145475.
Full textBanca: Juno Gallego
Banca: Maria Aparecida Larosa
Resumo: Este trabalho tem por objetivo realizar uma análise das propriedades mecânicas e microestruturais de componentes da liga Ti-6Al-4V produzidos pelo processo de Sinterização Direta de Metal por Laser (DMLS) que se baseia na deposição de camadas de um pó metálico que posteriormente são fundidas através de um feixe de laser de alta potência. Sendo assim, foram produzidos componentes em três orientações diferentes (A, B e C) com o propósito de verificar a influência das camadas sobre as propriedades mecânicas e nos micromecanismos de fratura, através dos ensaios de tração, fadiga e tenacidade à fratura e microscopia eletrônica de varredura (MEV). As amostras também foram submetidas a um tratamento térmico para alívio de tensões residuais provenientes do processo de fabricação e posteriormente analisadas através de microscopia óptica e difração de raios-X, para averiguar se houve mudanças em sua microestrutura ou decomposição de fase em relação a uma amostra sem tratamento térmico na condição "como produzida". As orientações de construção B e C apresentaram melhores valores em todos os ensaios mecânicos quando comparados à orientação A, evidenciando assim que houve perda de resistência mecânica, exceto no ensaio de microdureza, onde os valores médios não tiveram grandes variações com a orientação de manufatura. A amostra "como produzida" apresentou maiores valores de dureza quando comparada às amostras com tratamento de alívio de tensões residuais, fato este que ocorreu devido à precipitação da fase B e crescimento da fase a no material, que inicialmente apresentava uma estrutura composta por martensita hexagonal (a')
Abstract: This work has as objective to realize analysis of the mechanical and microstructural properties of Ti-6Al-4V alloy components produced by the Direct Metal Laser Sintering (DMLS) process that is based on the deposition of a metal powder layers and posteriorly fused by a high power laser beam. Therefore, components were produced in three different orientations (A, B and C) in order to verify the influence of the layers deposition on the mechanical properties and fracture micromechanisms, through the tensile tests, fatigue and tenacity of fracture and scanning electron microscopy (SEM). The samples were also subjected to a heat treatment to relieve residual stresses resulting from the manufacturing process and after analyzed through a optical microscopy and X-ray diffraction, to ascertain if there were changes in the microstructure or phase decomposition in relation to a sample without a heat treatment and at "as manufactured" condition. The construction orientation B and C have had better values in all mechanical tests when compared to the orientation A, revealing that had a loss of mechanical strength, except in the microhardness test, where the average values did not have large variations in the orientation of manufacturing. The sample "as manufactured" presented higher hardness values when compared to samples with treatment to relieve the residual stress, and this fact occurred due the precipitation of the B phase and the growth of the a phase in the material, which initially had a structure consisting of martensite hexagonal (a')
Mestre
Britto, Carlos Eduardo Silva [UNESP]. "Influência da orientação de prototipagem no comportamento mecânico da liga Ti-6Al-4V produzida por sinterização direta de metal por laser (DMLS)." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/145475.
Full textEste trabalho tem por objetivo realizar uma análise das propriedades mecânicas e microestruturais de componentes da liga Ti-6Al-4V produzidos pelo processo de Sinterização Direta de Metal por Laser (DMLS) que se baseia na deposição de camadas de um pó metálico que posteriormente são fundidas através de um feixe de laser de alta potência. Sendo assim, foram produzidos componentes em três orientações diferentes (A, B e C) com o propósito de verificar a influência das camadas sobre as propriedades mecânicas e nos micromecanismos de fratura, através dos ensaios de tração, fadiga e tenacidade à fratura e microscopia eletrônica de varredura (MEV). As amostras também foram submetidas a um tratamento térmico para alívio de tensões residuais provenientes do processo de fabricação e posteriormente analisadas através de microscopia óptica e difração de raios-X, para averiguar se houve mudanças em sua microestrutura ou decomposição de fase em relação a uma amostra sem tratamento térmico na condição como produzida. As orientações de construção B e C apresentaram melhores valores em todos os ensaios mecânicos quando comparados à orientação A, evidenciando assim que houve perda de resistência mecânica, exceto no ensaio de microdureza, onde os valores médios não tiveram grandes variações com a orientação de manufatura. A amostra como produzida apresentou maiores valores de dureza quando comparada às amostras com tratamento de alívio de tensões residuais, fato este que ocorreu devido à precipitação da fase B e crescimento da fase a no material, que inicialmente apresentava uma estrutura composta por martensita hexagonal (a')
This work has as objective to realize analysis of the mechanical and microstructural properties of Ti-6Al-4V alloy components produced by the Direct Metal Laser Sintering (DMLS) process that is based on the deposition of a metal powder layers and posteriorly fused by a high power laser beam. Therefore, components were produced in three different orientations (A, B and C) in order to verify the influence of the layers deposition on the mechanical properties and fracture micromechanisms, through the tensile tests, fatigue and tenacity of fracture and scanning electron microscopy (SEM). The samples were also subjected to a heat treatment to relieve residual stresses resulting from the manufacturing process and after analyzed through a optical microscopy and X-ray diffraction, to ascertain if there were changes in the microstructure or phase decomposition in relation to a sample without a heat treatment and at as manufactured condition. The construction orientation B and C have had better values in all mechanical tests when compared to the orientation A, revealing that had a loss of mechanical strength, except in the microhardness test, where the average values did not have large variations in the orientation of manufacturing. The sample as manufactured presented higher hardness values when compared to samples with treatment to relieve the residual stress, and this fact occurred due the precipitation of the B phase and the growth of the a phase in the material, which initially had a structure consisting of martensite hexagonal (a')
Asllani, Engjell. "Analisi sperimentale della resistenza a fatica di provini ottenuti per Additive Manufacturing." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2018.
Find full textKabbur, Nikhil. "Design and Manufacturing Guidelines for Additive Manufacturing of High Porosity Cellular Structures." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1504878916930908.
Full textRoque, Lidiane Kümpel [UNESP]. "Influência dos tratamentos térmicos na microestrutura e nos micromecanismos de fratura da liga ti-6al-4v produzida por sinterização direta de metal por laser (DMLS)." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/136111.
Full textA liga Ti-6A-4V é um biomaterial que tem se mostrado muito adequado na fabricação de implantes para reparar lesões craniofaciais. Entre outros requisitos, é importante que o implante resista a solicitação mecânica para garantir uma resposta clínica satisfatória de modo a proporcionar conforto e segurança ao paciente. O propósito específico do presente trabalho de pesquisa é determinar a influência de diferentes ciclos térmicos na microestrutura da amostra da Ti-6Al-4V produzida pelo processo de sinterização direta de metal por laser (DMLS) e no micromecanismo de fratura resultante de tensionamento uniaxial em tração. Para isso foram fabricados corpos-de-prova de tração, utilizando a técnica DMLS, e os mesmos foram submetidos a diferentes ciclos térmicos de 650 °C/1h, 650 °C/3h, 800 °C/4h e 850 °C/2h. Posteriormente, os corpos-de-prova foram submetidos a ensaios de tração. A caracterização microestrutural foi realizada com auxílio de microscopia óptica (MO) e eletrônica de varredura (MEV). As superfícies de fratura resultantes para as diferentes condições de ciclos térmicos foram analisadas por microscopia eletrônica de varredura. A microestrutura final da amostra como produzida resultante do processo de manufatura aditiva por DMLS revelou uma microestrutura martensita hexagonal α'. Para a amostra A6501H, a microestrutura martensítica resultante do processo DMLS não se decompôs. Na amostra A6503H a microestrutura martensítica começa a se decompor, pois são observados precipitados da fase β. Já nas amostras A8004H e A8502H observa-se uma estrutura (α +β), com cristais de fase α e fase β precipitada nos contornos. De acordo com a análise fractográfica todas as condições estudadas apresentaram fratura dúctil caracterizada pela formação e coalescência de microcavidades com forma e tamanhos variados
The Ti-6A-4V alloy is a biomaterial that has proved very suitable for the manufacture of prostheses to repair craniofacial injuries. Among other requirements, it is important that the prosthesis resist mechanical stress to ensure a satisfactory clinical response in order to provide comfort and safety to patients. The specific purpose of this research is to determine the influence of thermal cycles - as prototyped, 650 °C (1h); 650 °C (3h), 800 °C (2h) and 850 °C (4h) - on the microstructure and fracture micromechanisms resulting from uniaxial tension in traction. Therefore it was manufactured by DMLS technique bodies - of - proof traction which were subsequently subjected to different thermal cycles. Then, the bodies -specimens were subjected to tensile test. Microstructural characterization was carried out using optical and scanning electron microscopy (SEM). The resulting fracture surfaces of the five conditions for thermal cycling were analyzed by SEM. The final sample microstructure produced as a result of the additive manufacturing process DMLS revealed a hexagonal martensitic microstructure α '. For A6501H sample, the resulting martensitic microstructure DMLS process is not decomposed. In A6503H martensitic microstructure sample begins to decompose, as are observed precipitates of β phase. Already in the samples A8004H and A8502H observe a structure (α + β) with α and β phase crystal phase precipitated in the contours. According to fractographic analysis of all studied showed ductile fracture conditions characterized by the formation and coalescence wells with varying shape and sizes
Roque, Lidiane Kümpel. "Influência dos tratamentos térmicos na microestrutura e nos micromecanismos de fratura da liga ti-6al-4v produzida por sinterização direta de metal por laser (DMLS) /." Ilha Solteira, 2015. http://hdl.handle.net/11449/136111.
Full textCo-orientador: Maria Aparecida Larosa
Banca: Vicente Afonso Ventrella
Banca: Cecília Amelia de Carvalho Zavaglia
Resumo: A liga Ti-6A-4V é um biomaterial que tem se mostrado muito adequado na fabricação de implantes para reparar lesões craniofaciais. Entre outros requisitos, é importante que o implante resista a solicitação mecânica para garantir uma resposta clínica satisfatória de modo a proporcionar conforto e segurança ao paciente. O propósito específico do presente trabalho de pesquisa é determinar a influência de diferentes ciclos térmicos na microestrutura da amostra da Ti-6Al-4V produzida pelo processo de sinterização direta de metal por laser (DMLS) e no micromecanismo de fratura resultante de tensionamento uniaxial em tração. Para isso foram fabricados corpos-de-prova de tração, utilizando a técnica DMLS, e os mesmos foram submetidos a diferentes ciclos térmicos de 650 °C/1h, 650 °C/3h, 800 °C/4h e 850 °C/2h. Posteriormente, os corpos-de-prova foram submetidos a ensaios de tração. A caracterização microestrutural foi realizada com auxílio de microscopia óptica (MO) e eletrônica de varredura (MEV). As superfícies de fratura resultantes para as diferentes condições de ciclos térmicos foram analisadas por microscopia eletrônica de varredura. A microestrutura final da amostra como produzida resultante do processo de manufatura aditiva por DMLS revelou uma microestrutura martensita hexagonal α'. Para a amostra A6501H, a microestrutura martensítica resultante do processo DMLS não se decompôs. Na amostra A6503H a microestrutura martensítica começa a se decompor, pois são observados precipitados da fase β. Já nas amostras A8004H e A8502H observa-se uma estrutura (α +β), com cristais de fase α e fase β precipitada nos contornos. De acordo com a análise fractográfica todas as condições estudadas apresentaram fratura dúctil caracterizada pela formação e coalescência de microcavidades com forma e tamanhos variados
Abstract: The Ti-6A-4V alloy is a biomaterial that has proved very suitable for the manufacture of prostheses to repair craniofacial injuries. Among other requirements, it is important that the prosthesis resist mechanical stress to ensure a satisfactory clinical response in order to provide comfort and safety to patients. The specific purpose of this research is to determine the influence of thermal cycles - as prototyped, 650 °C (1h); 650 °C (3h), 800 °C (2h) and 850 °C (4h) - on the microstructure and fracture micromechanisms resulting from uniaxial tension in traction. Therefore it was manufactured by DMLS technique bodies - of - proof traction which were subsequently subjected to different thermal cycles. Then, the bodies -specimens were subjected to tensile test. Microstructural characterization was carried out using optical and scanning electron microscopy (SEM). The resulting fracture surfaces of the five conditions for thermal cycling were analyzed by SEM. The final sample microstructure produced as a result of the additive manufacturing process DMLS revealed a hexagonal martensitic microstructure α '. For A6501H sample, the resulting martensitic microstructure DMLS process is not decomposed. In A6503H martensitic microstructure sample begins to decompose, as are observed precipitates of β phase. Already in the samples A8004H and A8502H observe a structure (α + β) with α and β phase crystal phase precipitated in the contours. According to fractographic analysis of all studied showed ductile fracture conditions characterized by the formation and coalescence wells with varying shape and sizes
Mestre
Betti, Enrico <1984>. "Utilizzo in chirurgia ortognatica di dime di taglio per le osteotomie e placche di osteosintesi CAD-CAM stampate con tecnologia DMLS per l'osteotomia ed il riposizionamento mandibolare." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amsdottorato.unibo.it/8976/1/PDF%20TESI%20DOTTORATO%20-%20BETTI.pdf.
Full textObjective: the aim of this study is to evaluate the use of a new method for orthognathic surgery. The proposed method involves the integration of medicine with new technologies in order to test the use of cutting guides and CAD-CAM ostosynthesis plates for osteotomy and mandibular repositioning. Materials and Methods: the study takes into consideration 10 patients enrolled from July 2017 to May 2018, suffering from skeletal dento dysmorphia and undergoing orthognathic surgery. The 3D patient study and the virtual simulation of the intervention was performed with the IPS Case Designer software (KLS Martin, Germany). Based on the Virtual programming has been designed and implemented cutting guides and CAD-CAM mandibular osteosynthesis plates. All patients were operated with a mandibolar-first approach, using the individualized system. Post-operative data were compared with those of virtual planning in order to evaluate the accuracy of the method. Results: the accuracy of the mandibular repositioning was satisfactory and the errors were homogeneous between the cases.
Pereira, M. F. V. T., M. Williams, and Preez W. B. Du. "Characterization of metal powder based rapid prototyping components with respect to aluminium high pressure die casting process conditions." Journal for New Generation Sciences, Vol 8, Issue 2: Central University of Technology, Free State, Bloemfontein, 2010. http://hdl.handle.net/11462/563.
Full textThis paper is based on tests performed on die component specimens manufactured by EOS-DMLS (direct metal laser sintering) and LENS (laser engineered net shape) RP (rapid prototyping) technology platforms, as well as manufactured specimens machined out of preferred standard hot work steel DIN 1.2344. These specimens resemble typical components used in metal high pressure die casting tool sets. The specimens were subjected to a programme of cyclic immersion in molten aluminium alloy and cooling in water-based die release medium. The heat checking and soldering phenomena were analyzed through periodic inspections, monitoring crack formation and evidence of surface washout. At the end of the thermal tests, mechanical strength and hardness tests were performed to assess toughness and core resistance variations in relation to the initial conditions. Finally metallographic investigations were performed through optical microscopy on all the specimens considered. The outcomes of this research will be presented and used by the CSIR for further development and application of the assessed EOS-DMLS and LENS rapid prototyping technologies in rapid die manufacturing techniques and die design principles, including time and economic feasibility criteria to be applied when considering rapid die manufacture.
Bastos, Jaqueline Silva [UNESP]. "Reparo ósseo em scaffolds de TI6AL4V sinterizados pela tecnologia de sinterização direta de metais a laser (DMLS) submetidos a tratamento de superfície associado à aplicação de ultrassom de baixa intensidade (LIPUS)." Universidade Estadual Paulista (UNESP), 2016. http://hdl.handle.net/11449/138130.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
O objetivo desse estudo in vivo foi verificar a resposta óssea de scaffolds porosos revestidos processados pela técnica de Sinterização Direta de Metais a laser (DMLS) associado à terapia de ultrassom de baixa intensidade. Os scaffolds foram processados empregando a técnica DMLS e tratados termicamente a 1000°C por 24 horas. Três tipos de tratamento de superfície foram avaliados: Alcalino, biomimético e imobilização de alendronato de sódio. Para o tratamento alcalino, as amostras foram imersas na solução de NaOH (5M) a 60ºC por 24 horas. O tratamento biomimético consistiu na imersão dos scaffolds em solução SBF (SimulatedBodyFluid) enquanto a imobilização do alendronato foi realizada a partir da imersão dos scaffolds em uma solução formada por SBF e medicamento durante 5 dias. As superfícies dos scaffolds foram avaliadas para cada etapa empregando microscopia eletrônica de varredura (MEV) e análise por difração de raios-X. Os scaffolds foram implantados na tíbia direita de 85 ratos machos da raça wistar com idade média de 12 semanas. A microtomografia computadorizada (µCT) e análise histológica foram realizadas para avaliar o reparo ósseo no defeito. As micrografias das superfícies obtidas mostraram mudanças no aspecto da superfície e composição química de acordo com o tratamento. O tratamento biomimético promoveu o crescimento da apatita sobre a superfície enquanto a imobilização com alendronato suprimiu sua formação. As imagens obtidas na microtomografia mostraram elevado valor de densidade óssea para o último grupo. No entanto, análises histológicas mostraram a formação de cápsula fibrosa em torno dos scaffolds a qual foi minimizada usando ultrassom pulsado de baixa intensidade. No entanto, mais estudos precisam ser realizados para avaliar a influência da geometria dos scaffolds na incorporação de medicamentos.
The objective of this in vivo study was to verify the bone response of coated Ti6Al4V porous scaffolds processed by Direct Metal Laser Sintering (DMLS) technique associated to low intensity pulsed ultrasound therapy. Scaffolds were processed by using Direct Metal Laser Sintering technique (DMLS) and heat treated at 1000 °C for 24 hours. Three types of surface treatments were evaluated: alkaline, biomimetic and sodium alendronate immobilization. For alkaline treatment, samples were immersed in a NaOH (5M) solution at 60ºC for 24 hours. Biomimetic treatment consisted in the immersion of the scaffolds into Simulated Body Fluid solution while for sodium alendronato immobilization the scaffolds were immersed in the solution formed by SBF plus drug during 5 days. The scaffolds surfaces were evaluated after each step employing SEM (Scanning Electron Microscopy)and X-rays diffraction analysis(XRD). Scaffolds were implanted into right tibia of 85 male Wistar rats with average age of 12 weeks. X-rays micro-computed tomography (µCT) and histological analysis were carried out to evaluate the bone repair on the defect. Micrographs analysis showed that the aspect of the surfaces and chemical composition changed according treatment. Biomimetic treatment promoted the growth of the apatite on the surface; in contrast the immobilization of alendronate suppressed apatite formation. Micro CT images showed higher value of bone density for the last group. However, histological analysis showed the formation of encapsulation fibrous around the scaffolds. This formation was minimized by using low intensity pulsed ultrasound technique, however, more studies can be carried out to evaluate the influence of scaffolds geometry in the drug incorporation.
Bastos, Jaqueline Silva. "Reparo ósseo em Scaffolds de Ti6Al4V sinterizados pela tecnologia de Sinterização Direta de Metais a Laser (DMLS) submetidos a tratamento de superfície associado à aplicação de ultrassom de baixa intensidade (LIPUS) /." Guaratinguetá, 2016. http://hdl.handle.net/11449/138130.
Full textBanca: André Luiz Jardini Munhoz
Banca: Ricardo Tadeu Lopes
Banca: Orivaldo Lopes da Silva
Banca: Ana Lia Anbinder
Resumo: O objetivo desse estudo in vivo foi verificar a resposta óssea de scaffolds porosos revestidos processados pela técnica de Sinterização Direta de Metais a laser (DMLS) associado à terapia de ultrassom de baixa intensidade. Os scaffolds foram processados empregando a técnica DMLS e tratados termicamente a 1000°C por 24 horas. Três tipos de tratamento de superfície foram avaliados: Alcalino, biomimético e imobilização de alendronato de sódio. Para o tratamento alcalino, as amostras foram imersas na solução de NaOH (5M) a 60ºC por 24 horas. O tratamento biomimético consistiu na imersão dos scaffolds em solução SBF (SimulatedBodyFluid) enquanto a imobilização do alendronato foi realizada a partir da imersão dos scaffolds em uma solução formada por SBF e medicamento durante 5 dias. As superfícies dos scaffolds foram avaliadas para cada etapa empregando microscopia eletrônica de varredura (MEV) e análise por difração de raios-X. Os scaffolds foram implantados na tíbia direita de 85 ratos machos da raça wistar com idade média de 12 semanas. A microtomografia computadorizada (µCT) e análise histológica foram realizadas para avaliar o reparo ósseo no defeito. As micrografias das superfícies obtidas mostraram mudanças no aspecto da superfície e composição química de acordo com o tratamento. O tratamento biomimético promoveu o crescimento da apatita sobre a superfície enquanto a imobilização com alendronato suprimiu sua formação. As imagens obtidas na microtomografia mostraram elevado valor de densidade óssea para o último grupo. No entanto, análises histológicas mostraram a formação de cápsula fibrosa em torno dos scaffolds a qual foi minimizada usando ultrassom pulsado de baixa intensidade. No entanto, mais estudos precisam ser realizados para avaliar a influência da geometria dos scaffolds na incorporação de medicamentos
Abstract: The objective of this in vivo study was to verify the bone response of coated Ti6Al4V porous scaffolds processed by Direct Metal Laser Sintering (DMLS) technique associated to low intensity pulsed ultrasound therapy. Scaffolds were processed by using Direct Metal Laser Sintering technique (DMLS) and heat treated at 1000 °C for 24 hours. Three types of surface treatments were evaluated: alkaline, biomimetic and sodium alendronate immobilization. For alkaline treatment, samples were immersed in a NaOH (5M) solution at 60ºC for 24 hours. Biomimetic treatment consisted in the immersion of the scaffolds into Simulated Body Fluid solution while for sodium alendronato immobilization the scaffolds were immersed in the solution formed by SBF plus drug during 5 days. The scaffolds surfaces were evaluated after each step employing SEM (Scanning Electron Microscopy)and X-rays diffraction analysis(XRD). Scaffolds were implanted into right tibia of 85 male Wistar rats with average age of 12 weeks. X-rays micro-computed tomography (µCT) and histological analysis were carried out to evaluate the bone repair on the defect. Micrographs analysis showed that the aspect of the surfaces and chemical composition changed according treatment. Biomimetic treatment promoted the growth of the apatite on the surface; in contrast the immobilization of alendronate suppressed apatite formation. Micro CT images showed higher value of bone density for the last group. However, histological analysis showed the formation of encapsulation fibrous around the scaffolds. This formation was minimized by using low intensity pulsed ultrasound technique, however, more studies can be carried out to evaluate the influence of scaffolds geometry in the drug incorporation
Doutor
Biancoli, Giacomo. "Additive manufacturing: ricerca sui principali fattori che influenzano il comportamento a fatica." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2017.
Find full textPalmer, Andrew. "The Design and Development of an Additive Fabrication Process and Material Selection Tool." Master's thesis, University of Central Florida, 2009. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3635.
Full textM.S.
Department of Industrial Engineering and Management Systems
Engineering and Computer Science
Industrial Engineering MS
Coffy, Kevin. "Microstructure and Chemistry Evaluation of Direct Metal Laser Sintered 15-5 PH Stainless Steel." Master's thesis, University of Central Florida, 2014. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/6256.
Full textM.S.M.E.
Masters
Materials Science Engineering
Engineering and Computer Science
Materials Science and Engineering
Hossain, Mohammad Arif. "Sweeping Jet Film Cooling." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1586462423029754.
Full textAsar, Munevver Elif. "Investigating Turbine Vane Trailing Edge Pin Fin Cooling in Subsonic and Transonic Cascades." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu155551385206548.
Full textDeml, Christoph. "Analyse und Modellierung des DMOS-Transistors." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969618816.
Full textDeml, Christoph Hoffmann Kurt. "Analyse und Modellierung des DMOS-Transistors." Neubiberg Universitätsbibliothek der Universität der Bundeswehr, 2008. http://d-nb.info/998614890/34.
Full textFaigle, Christopher Tyler. "DMS-Splines and radiosity." Thesis, University of Cambridge, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624727.
Full textHung, Merit Y. (Merit Yi). "Double diffused (DMOS) FETs for analog applications." Thesis, Massachusetts Institute of Technology, 1990. http://hdl.handle.net/1721.1/13698.
Full textAngel, Mattias, and Albert Berggren. "Regionala DMOs marknadsföring och sociala mediers påverkan." Thesis, Mittuniversitetet, Institutionen för ekonomi, geografi, juridik och turism, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-39247.
Full textDestination management organizations (DMOs) are usually structured by two or more member-organizations. One of the main tasks for a DMO is to market the destination. Social medias have changed the way a lot of organizations manages their marketing. Communication has gone from a static one directional, from the producer to the consumer, to a more dynamic two-way communication where the interaction between the two parts has become more important. In this paper we examine how swedish regional DMOs use social medias in their marketing. The empirical data has been gathered by qualitative semi-structured interviews with persons who work with marketing at four different swedish regional DMOs. This has been combined with analysis of the concerned DMOs social media pages on Facebook and Instagram. The results show that the different organizations have both similarities and differences in their strategic and operative use of social media in marketing efforts.
2020-06-08
Zupac, Dragan. "Radiation-induced mobility degradation in DMOS transistors." Diss., The University of Arizona, 1993. http://hdl.handle.net/10150/186456.
Full textGiske, Mats Andreas. "DML in VIDEO-CONFERENCING APPLICATIONS." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for elektronikk og telekommunikasjon, 2012. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-19416.
Full textSchepp, Oliver. "Simulations- und Meßmethoden zur Bestimmung der Temperatur von LeistungsMOSFETs /." Düsseldorf : VDI-Verl, 1998. http://www.gbv.de/dms/bs/toc/251116484.pdf.
Full textAdam, Banafscheh. "DMPS und Dimercaprol in der Therapie der akuten Arsenintoxikation." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=972308113.
Full textAdolph, Daniela. "Zunahme der renalen Quecksilberausscheidung durch DMPS bei chronischer Quecksilbervergiftung." Diss., lmu, 2007. http://nbn-resolving.de/urn:nbn:de:bvb:19-79299.
Full textLundén, Jenny. "Atmospheric DMS in the High Arctic." Stockholm : Department of Meteorology, Stockholm University, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-38178.
Full textAt the time of the doctoral defense the following papers were unpublished and had a status as follows: Paper 1: Manuscript. Paper 2: Manuscript. Paper 4: Manuscript.
Lundén, Jenny. "Atmospheric DMS in the High Arctic." Doctoral thesis, Stockholms universitet, Meteorologiska institutionen (MISU), 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-38178.
Full textAt the time of the doctoral defense the following papers were unpublished and had a status as follows: Paper 1: Manuscript. Paper 2: Manuscript. Paper 4: Manuscript.
Elbashiri, Ali. "Distributed Marking System (DMS), cORBA implementation." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0007/MQ45367.pdf.
Full textŽáček, Jan. "Pilotní zavádění DMS v bankovním prostředí." Master's thesis, Vysoká škola ekonomická v Praze, 2014. http://www.nusl.cz/ntk/nusl-202082.
Full textFeumi-Jantou, Charles. "Rôle du récepteur CX3CR1 dans la dégénérescence maculaire liée à l'âge (DMLA)." Thesis, Paris 5, 2012. http://www.theses.fr/2012PA05T066.
Full textAge-related macular degeneration (AMD) is the leading cause of vision loss in elderly people in theindustrialized countries. Early AMD is characterized by yellowish white dots called drusen, clinically visible withfunduscopy. There are two clinical forms of late AMD: the fast progressive “wet” form defined by choroidalneovascularisation, responsible for the most part of legal blindness in AMD, and the more slowly progressive “atrophic”form characterized by RPE atrophy, photoreceptor degeneration and choroidal involution. “Wet” AMD is the onlytreated form Epidemiological studies have helped to identify key factors in its pathogenesis. Age, family history andgenetic are the principal predisposing factors. Over the past few years, numerous studies have focused on the role ofchemotactic cytokines, also known as chemokines and their receptors. Retinal microglial cells (MC) express CX3CR1.The role of retinal microglial cells (MC) in age-related macular degeneration (AMD) is unclear. This study shows thatall retinal MC express the chemokine receptor CX3CR1 and that homozygosity for the CX3CR1 M280 allele, which isassociated with impaired cell migration, increases the risk of AMD. We found that in humans with AMD, MCaccumulated in the subretinal space at sites of retinal degeneration and of choroidal neovascularization. In CX3CR1-deficient mice, MC accumulated subretinally with age and albino background and after laser impact preceding retinaldegeneration. The appearance of lipid-bloated subretinal MC is drusen-like on funduscopy of senescent mice, andCX3CR1-dependent MC accumulation is associated with an exacerbation of experimental choroidal neovascularization.These results show that CX3CR1-dependent accumulation of subretinal MC evokes cardinal features of AMD. Thesefindings as new pathogenic process might be useful for new therapies development