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1

Ehsaninia, Jamshid, Mohammad Bagher Zandi, Moein Taned, and Alireza Bagheripour. "Bayesian approach to estimate variance components and genetic parameters of dairy traits and somatic cell score in Murciano-Granadina goats." Journal of Agricultural Science 163, no. 3 (2025): 352–62. https://doi.org/10.1017/s0021859625000267.

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AbstractThe aim of this study was to estimate genetic parameters for dairy traits (daily milk yield (DMY), daily milk fat yield (DMFY), and daily milk protein yield (DMPY)) and somatic cell score (SCS) of Iranian Murciano-Granadina goats. The analysis involved 99,839 records from 4,307 does, spanning from 2015 to 2021. A single-trait animal model was used to obtain estimates of genetic and residual (co)variances and heritabilities. In the model, both fixed effects (birth year, parity, litter size, age dam (day)) and random effects (additive animal genetic effects) were considered. R software w
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2

Chen, Yun, Hui-Qin Luo, Lin-Lin Sun, et al. "Dihydromyricetin Attenuates Myocardial Hypertrophy Induced by Transverse Aortic Constriction via Oxidative Stress Inhibition and SIRT3 Pathway Enhancement." International Journal of Molecular Sciences 19, no. 9 (2018): 2592. http://dx.doi.org/10.3390/ijms19092592.

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Dihydromyricetin (DMY), one of the flavonoids in vine tea, exerts several pharmacological actions. However, it is not clear whether DMY has a protective effect on pressure overload-induced myocardial hypertrophy. In the present study, male C57BL/6 mice aging 8–10 weeks were subjected to transverse aortic constriction (TAC) surgery after 2 weeks of DMY (250 mg/kg/day) intragastric administration. DMY was given for another 2 weeks after surgery. Blood pressure, myocardial structure, cardiomyocyte cross-sectional area, cardiac function, and cardiac index were observed. The level of oxidative stre
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3

Yousif M. S. Al-Barzinji and Fahad K. Zainal. "GENETIC EVALUATION OF MILK PRODUCTION TRAITS IN LOCAL GOAT." IRAQI JOURNAL OF AGRICULTURAL SCIENCES 54, no. 6 (2023): 1548–56. http://dx.doi.org/10.36103/ijas.v54i6.1855.

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This study was conducted on 67 local doe goat, aged from 2-5 years old. The overall mean of TMY, DMY and lactation length of 1st and 2nd flocks were (130.541 ± 7.403 kg, 0.716 ± 0.033kg, and 182.432 ± 4.112 day) and (164.043 ± 8.788 kg, 0.832 ± 0.043 kg, 197.027 ± 2.650 day), respectively. The flock, age of doe, doe coat color, month of kidding and type of birth have significant effect on TMY and DMY, doe in 2nd flock production 33.502 and 0.116 kg milk/doe, respectively more than doe in 1st flock. Doe of five years old yielded (181.878 ± 10.171 kg /doe) and (0.892 ± 0.044 kg /doe/day) more mi
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Dong, Jianxia, Shu Wang, Jiamin Mao, et al. "Preparation of Dihydromyricetin-Loaded Self-Emulsifying Drug Delivery System and Its Anti-Alcoholism Effect." Pharmaceutics 15, no. 9 (2023): 2296. http://dx.doi.org/10.3390/pharmaceutics15092296.

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Intraperitoneal injection of dihydromyricetin (DMY) has shown promising potential in the treatment of alcoholism. However, its therapeutic effect is limited due to its low solubility, poor stability, and high gut-liver first-pass metabolism, resulting in very low oral bioavailability. In this study, we developed a DMY-loaded self-emulsifying drug delivery system (DMY-SEDDS) to enhance the oral bioavailability and anti-alcoholism effect of DMY. DMY-SEDDS improved the oral absorption of DMY by facilitating lymphatic transport. The area under the concentration-time curve (AUC) of DMY in the DMY-S
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Koç, Atakan, and Ramazan Gürses. "A Study on Milk Yield, Fertility and Milk Quality Characteristics of Primiparous Red-Holstein and Holstein-Friesian Cows." Turkish Journal of Agriculture - Food Science and Technology 8, no. 12 (2020): 2562–69. http://dx.doi.org/10.24925/turjaf.v8i12.2562-2569.3690.

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The aim of this study was to determine the reproductive characteristics, milk yield and milk quality of Primiparous Red-Holstein (RH) and Holstein-Friesian (HF) cows. For this aim, records and monthly taken milk samples of 83 RH and 14 HF raised on a farm in Aydın, Turkey were used. The averages of the first calving age (FCA), gestation length (GL), days open (DO), calving interval (CI), daily milk yield (DMY), 305-day milk yield (305-dMY), solid non-fat (SNF) and Log10 somatic cell count (Log10SCC) of milk were found to be 27.6±0.24 mo, 278.4±1.09 d, 144.0±7.12 d, 421.4±7.66 d, 22.7±0.21 kg,
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6

Qi, Ling-Xiao, Xue-Ting Wang, Jin-Ping Huang, et al. "Silver Nanoparticles Encapped by Dihydromyricetin: Optimization of Green Synthesis, Characterization, Toxicity, and Anti-MRSA Infection Activities for Zebrafish (Danio rerio)." International Journal of Molecular Sciences 25, no. 10 (2024): 5255. http://dx.doi.org/10.3390/ijms25105255.

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To achieve the environmentally friendly and rapid green synthesis of efficient and stable AgNPs for drug-resistant bacterial infection, this study optimized the green synthesis process of silver nanoparticles (AgNPs) using Dihydromyricetin (DMY). Then, we assessed the impact of AgNPs on zebrafish embryo development, as well as their therapeutic efficacy on zebrafish infected with Methicillin-resistant Staphylococcus aureus (MRSA). Transmission electron microscopy (TEM) and dynamic light-scattering (DLS) analyses revealed that AgNPs possessed an average size of 23.6 nm, a polymer dispersity ind
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7

Mohsen, M. K., E. S. Tawfik, A. Y. Salem, and H. G. El-Awady. "Study on Friesian Herds Raised in Egypt and Germany – II. Genetic and phenotypic trends in estimated transmitting ability." Archives Animal Breeding 43, no. 4 (2000): 399–410. http://dx.doi.org/10.5194/aab-43-399-2000.

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Abstract. Original data consisted of 774 first lactation records of daughters of 124 sires of Friesian herds in Egypt and 9219 first lactation records of daughters of 679 sires of Friesian herds in Germany used to estimate genetic and phenotypic trends of initial milk yield in 70 days (IMY), 305-day milk yield (305-dMY), lactation period (LP) and calving interval (CI). Sire component of variance was consistently about 9.88%, 10.75%, 4.63% and 5.03% for IMY, 305-dMY, LP and CI, respectively of the total Variation in Friesian cows in Egypt and about 16.69%, 16.69%, 3.63% and 4.37%, for IMY, 305-
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8

Liu, Dan, Jun Luo, Hao Wang, Lijun Ding, and Xin-An Zeng. "Synthesis of Dihydromyricetin Coated Multi-Walled Carbon Nanotubes (MWCNTs) and Antibacterial Activities." Journal of Nanoscience and Nanotechnology 20, no. 10 (2020): 6148–54. http://dx.doi.org/10.1166/jnn.2020.18002.

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The weak antimicrobial property of multi-walled carbon nanotubes (MWCNTs) hampers their use as an antimicrobial material. In the report, Dihydromyricetin (DMY) coated multi-walled carbon nanotubes (MWCNTs-DMY) were prepared with poly(ethylene glycol) (PEG1000) as a linker and evaluated for inactivating pathogenic bacteria. UV-visible spectra, FT-IR, transmission electron microscopy (TEM), and thermal gravimetric analysis (TGA) were used to characterize the MWCNTs-DMY. It has been shown that PEG and DMY are covalently attached to MWCNTs with excellent stability. Vibrio parahaemolyticus was empl
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9

Hering, Pavel, Pavel Kopunecz, Oto Hanuš, et al. "Development to Ensure of the Result Reliability of Production Indicators in the Milk Recording During its Computerization." Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis 64, no. 3 (2016): 791–801. http://dx.doi.org/10.11118/actaun201664030791.

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Milk recording (MR) is an essential breeder measure. Results are important for inheritance check. The occurrence of errors in the data may compromise the efficiency of breeding of dairy cows. The aim was possibility to reduce the incidence of MR database errors. Analyses of frequency distribution of MR data deviations from different sources and estimations of limits of difference acceptability in milk recording were performed. The results of MR control days of flowmeter in parlor (DMY) were paired to the AVG7 results (average for 7 days) from the same flowmeter (n = 16,247, original recordings
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10

Li, Juan, Mingxing Yin, Maoxian Tian, Jianguo Fang, and Hanlin Xu. "Stiff-Soft Hybrid Biomimetic Nano-Emulsion for Targeted Liver Delivery and Treatment of Early Nonalcoholic Fatty Liver Disease." Pharmaceutics 16, no. 10 (2024): 1303. http://dx.doi.org/10.3390/pharmaceutics16101303.

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Background: Nonalcoholic fatty liver disease (NAFLD) poses a risk for numerous metabolic diseases. To date, the U.S. Food and Drug Administration has not yet approved any medications for the treatment of NAFLD, for which developing therapeutic drugs is urgent. Dihydromyricetin (DMY), the most abundant flavonoid in vine tea, has been shown to be hepatoprotective. Its application was limited by low bioavailability in vivo; Methods: In order to improve the bioavailability of DMY and achieve liver-targeted delivery, we designed a DMY-loaded stiff-soft hybrid biomimetic nano drug delivery system (D
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11

Atil, H., and A. S. Khattab. "A comparison of different methods of estimating sire transmitting ability of some milk traits in a herd of Holstein Friesian cattle." Archives Animal Breeding 43, no. 2 (2000): 115–22. http://dx.doi.org/10.5194/aab-43-115-2000.

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Abstract. A total of 1931 normal first lactation records of Holstein Friesian cows kept at Dena Farm in Egypt during the period from 1987 to 1994 were used to estimate phenotypic and genetic parameters for 90 day milk yield (90 dMY), 305 day milk yield (305 dMY) and lactation period (LP). In addition, 76 bulls with at least ten daughters were used to compare three methods of sire transmitting ability. A least Squares analysis of variance show significant effect of month and year of calving and age at first calving for different traits studied, except the effect of age at first calving on LP. H
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12

Ren, Yupeng, Jianhui An, Cheng Tian, Longchen Shang, Yexing Tao, and Lingli Deng. "Air-Assisted Electrospinning of Dihydromyricetin-Loaded Dextran/Zein/Xylose Nanofibers and Effects of the Maillard Reaction on Fiber Properties." Molecules 29, no. 13 (2024): 3136. http://dx.doi.org/10.3390/molecules29133136.

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Dihydromyricetin (DMY) has been encapsulated in delivery systems to address the solubility limitations of DMY in water and improve its bioavailability. Air-assisted electrospinning has been used as a novel technology to load DMY. To evaluate the impact of adding DMY to dextran/zein nanofibers and understand the effects of the Maillard reaction (MR) on the physical and functional properties of DMY-loaded nanofibers, dextran/zein/xylose nanofibers with 0%, 1%, 2%, 3%, and 4% DMY were fabricated, followed by MR crosslinking. Scanning electron microscopy (SEM) observations indicated that the addit
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13

JENKO, Janez, Tomaž PERPAR, Betka LOGAR, Jože VERBIČ, and Milena KOVAČ. "Comparison of calculation methods of daily milk yield, fat and protein contents from AM/PM milkings." Acta agriculturae Slovenica, no. 2 (September 15, 2008): 195–200. http://dx.doi.org/10.14720/aas-s.2008.2.19247.

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For prediction of daily milk yield (DMY), daily fat percentage (DFP), and daily protein percentage (DPP) from alternate AM/PM recording scheme, three different methods were tested. The data comprised information on 483 813 test-day records. Methods were compared on the whole data set or just on the upper or the lower quartile of the records according to DMY, DFP, DPP, and milking interval (MI). Method 1 included DMY, DFP or DPP as a dependent variable in regression analysis. In Method 2 ratio of partial AM/PM to daily yield was included as a dependent variable, whereas Method 3 is based on dou
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14

Kim, Chemere, and Sung. "Effect of Heavy Rainfall Events on the Dry Matter Yield Trend of Whole Crop Maize (Zea mays L.)." Agriculture 9, no. 4 (2019): 75. http://dx.doi.org/10.3390/agriculture9040075.

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The objective of this study was to detect the historical dry matter yield (DMY) trend and to evaluate the effects of heavy rainfall events on the observed DMY trend of whole crop maize (WCM, Zea mays L.) using time-series analysis in Suwon, Republic of Korea. The climatic variables corresponding to the seeding to harvesting period, including the growing degree days, mean temperature, etc., of WCM along with the DMY data (n = 543) during 1982–2011, were used in the analysis. The DMY trend was detected using Autoregressive Integrated Moving Average with the explanatory variables (ARIMAX) form of
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15

Zhang, Jianzhi. "Evolution of DMY, a Newly Emergent Male Sex-Determination Gene of Medaka Fish." Genetics 166, no. 4 (2004): 1887–95. http://dx.doi.org/10.1093/genetics/166.4.1887.

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Abstract The Japanese medaka fish Oryzias latipes has an XX/XY sex-determination system. The Y-linked sex-determination gene DMY is a duplicate of the autosomal gene DMRT1, which encodes a DM-domain-containing transcriptional factor. DMY appears to have originated recently within Oryzias, allowing a detailed evolutionary study of the initial steps that led to the new gene and new sex-determination system. Here I analyze the publicly available DMRT1 and DMY gene sequences of Oryzias species and report the following findings. First, the synonymous substitution rate in DMY is 1.73 times that in D
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16

Feng, Liyun, Dongdong Que, Zehua Li, et al. "Dihydromyricetin ameliorates vascular calcification in chronic kidney disease by targeting AKT signaling." Clinical Science 135, no. 21 (2021): 2483–502. http://dx.doi.org/10.1042/cs20210259.

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Abstract Vascular calcification is highly prevalent in chronic kidney disease (CKD), and is characterized by transdifferentiation from contractile vascular smooth muscle cells (VSMCs) into an osteogenic phenotype. However, no effective and therapeutic option to prevent vascular calcification is yet available. Dihydromyricetin (DMY), a bioactive flavonoid isolated from Ampelopsis grossedentata, has been found to inhibit VSMCs proliferation and the injury-induced neointimal formation. However, whether DMY has an effect on osteogenic differentiation of VSMCs and vascular calcification is still un
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Zhang, Haolin, Giovanni Caprioli, Hidayat Hussain, Nguyen Phan Khoi Le, Mohamed A. Farag, and Jianbo Xiao. "A multifaceted review on dihydromyricetin resources, extraction, bioavailability, biotransformation, bioactivities, and food applications with future perspectives to maximize its value." eFood 2, no. 4 (2021): 164–84. http://dx.doi.org/10.53365/efood.k/143518.

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Natural bioactive compounds present a better alternative to prevent and treat chronic diseases owing to their lower toxicity and abundant resources. (+)-Dihydromyricetin (DMY) is a flavanonol, possessing numerous interesting bioactivities with abundant resources. This review provides a comprehensive overview of the recent advances in DMY natural resources, stereoisomerism, physicochemical properties, extraction, biosynthesis, pharmacokinetics, and biotransformation. Stereoisomerism of DMY should be considered for better indication of its efficacy. Biotechnological approach presents a potential
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18

Chen, Lei, Chao Wang, Qingyi Wei, Zhengxiang Ning та Erdong Yuan. "Interaction of Dihydromyricetin and α-Amylase". Natural Product Communications 8, № 3 (2013): 1934578X1300800. http://dx.doi.org/10.1177/1934578x1300800317.

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The interaction of dihydromyricetin (DMY) and α-amylase was investigated. The complex formed between DMY and α-amylase resulted in decreased antioxidant activity of DMY and the catalytic activity of the enzyme, as well as efficient quenching of the intrinsic fluorescence of α-amylase. An α-amylase molecule provides one binding site for a DMY molecule. These results will be useful for exploiting this compound to combat diseases efficiently.
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Xiao, Xiao-Nian, Fan Wang, Yi-Ting Yuan, Jing Liu, Yue-Zhen Liu, and Xing Yi. "Antibacterial Activity and Mode of Action of Dihydromyricetin from Ampelopsis grossedentata Leaves against Food-Borne Bacteria." Molecules 24, no. 15 (2019): 2831. http://dx.doi.org/10.3390/molecules24152831.

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Dihydromyricetin (DMY) has recently attracted increased interest due to its considerable health-promoting activities but there are few reports on its antibacterial activity and mechanism. In this paper, the activity and mechanisms of DMY from Ampelopsis grossedentata leaves against food-borne bacteria are investigated. Moreover, the effects of pH, thermal-processing, and metal ions on the antibacterial activity of DMY are also evaluated. The results show that DMY exhibits ideal antibacterial activity on five types of food-borne bacteria (Staphylococcus aureus, Bacillus subtilis, Escherichia co
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Du, Lixin, Huiling Lu, Yifei Xiao, Zhihua Guo, and Ya Li. "Protective effect and pharmacokinetics of dihydromyricetin nanoparticles on oxidative damage of myocardium." PLOS ONE 19, no. 4 (2024): e0301036. http://dx.doi.org/10.1371/journal.pone.0301036.

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Purpose This study aims to investigate the protective mechanism of dihydromyricetin PLGA nanoparticles (DMY-PLGA NPs) against myocardial ischemia-reperfusion injury (MIRI) in vitro and the improvement of oral bioavailability in vivo. Methods DMY-PLGA NPs was prepared and characterized by emulsifying solvent volatilization, and the oxidative stress model of rat H9c2 cardiomyocyte induced by H2O2 was established. After administration, cell survival rate, lactate dehydrogenase (LDH), malondialdehyde (MDA) and superoxide dismutase (SOD) were detected, and the expressions of PGC1α and PPARα were de
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Špehar, Marija, Ante Kasap, Boro Mioč, Zdravko Barać, and Danijel Mulc. "Estimation of genetic parameters for dairy traits using repeatability animal models based on test-day data for Alpine goat in Croatia." Mljekarstvo 69, no. 4 (2019): 215–21. http://dx.doi.org/10.15567/mljekarstvo.2019.0401.

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The objective of this study was to estimate genetic parameters for daily milk yield (DMY), fat (FC), and protein content (PC) using 329.022 test-day records of 23.756 Alpine does. Single trait repeatability animal model was applied. Parity, litter size, season, and lactation stage (Ali-Schaeffer’s curve) were fitted in the fixed, while herd, herd-test-day, permanent environment (within lactations) and additive genetic effect in the random part of the model. Variance components were estimated using Residual Maximum Likelihood Method in the VCE-6 program. Additive genetic effect explained 23 %,
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Mardenli, Omar R. "The Progeny test of Friesian sires for milk traits by using the contemporary comparison method." Revista Colombiana de Ciencia Animal - RECIA 13, no. 1 (2021): e747. http://dx.doi.org/10.24188/recia.v13.n1.2021.747.

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In this study, the contemporary comparison method (CC) of half-sibs relation was used to estimate the breeding values of Holstein-Friesian sires for 305 -day milk yield (305-DMY) and basic components of milk traits, 409 records of cows that are daughters of ten sires in eight Syrian dairy farms where used. Result of the study showed differences in the estimated breeding values(ccEBVs), where the E Sire achieved the highest value of 305-DMY trait (254.47 kg), while the B Sire achieved the highest value of milk protein percentage (MPP), milk fat percentage (MFP)and milk lactose percentage (MLP)
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Yang, Zhousheng, Tianyu Li, Chunyan Wang, Mingyu Meng, Shenglan Tan та Lei Chen. "Dihydromyricetin Inhibits M1 Macrophage Polarization in Atherosclerosis by Modulating miR-9-Mediated SIRT1/NF-κB Signaling Pathway". Mediators of Inflammation 2023 (17 травня 2023): 1–11. http://dx.doi.org/10.1155/2023/2547588.

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Dihydromyricetin (DMY), a natural flavonoid compound extracted from the stems and leaves of Ampelopsis grossedentata, has been found as a potential therapeutic chemical for treating atherosclerosis. This study explores the underlying mechanism of DMY repressing M1 macrophage polarization in atherosclerosis. We showed that DMY treatment markedly decreased M1 macrophage markers (e.g., Tnf-α and IL-1β) and p65-positive macrophage numbers in the vessel wall of Apoe-deficient (Apoe–/–) mice. Overexpression of miR-9 or knockdown of SIRT1 in macrophages reversed the effect of DMY on M1 macrophage pol
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Yin, Hongmei, Qiaohua Yan, Yinglun Li та Huaqiao Tang. "Dihydromyricetin Nanoparticles Alleviate Lipopolysaccharide-Induced Acute Kidney Injury by Decreasing Inflammation and Cell Apoptosis via the TLR4/NF-κB Pathway". Journal of Functional Biomaterials 15, № 9 (2024): 249. http://dx.doi.org/10.3390/jfb15090249.

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Acute kidney injury (AKI) is the most severe and fatal complication of sepsis resulting from infectious trauma. Currently, effective treatment options are still lacking. Dihydromyricetin is the main component extracted from Vine tea (Ampelopsis megalophylla Diels et Gilg). In our previous research, chitosan–tripolyphosphate-encapsulated nanoparticles of dihydromyricetin (CS-DMY-NPs) have been proven to have potential protective effects against cisplatin-induced AKI. Here, we investigated the protective effects and mechanisms of DMY and its nano-formulations against LPS-induced AKI by assessing
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Dobos, R. C., F. A. P. Alvarenga, H. Bansi, et al. "Mapping variability of pasture sward height, dry matter availability and disappearance during grazing." Crop and Pasture Science 72, no. 7 (2021): 551. http://dx.doi.org/10.1071/cp20347.

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This study investigated whether geostatistical methods can be applied to severely drought-affected pastures to assess spatial variability in sward height (SH) and dry matter yield (DMY) and change in SH and DM in response to grazing. Geo-referenced SH data were collected using a rapid, non-destructive method (rapid pasture meter) and analysed by geostatistical methodology. Eight severely drought-affected paddocks (~1.25 ha) were grazed individually by two groups of 20 Angus heifers in two 28-day phases (P1 and P2) between 2 July and 29 August 2019. Pasture DMY was estimated from calibration eq
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Ameen, Nihad Ahmad Ameen, and Salim Omar Raoof Raoof. "The Effect of Sex Chromatin on Some Reproductive Traits of local Sheep in Erbil." Journal of Biotechnology Research Center 9, no. 2 (2015): 6–10. http://dx.doi.org/10.24126/jobrc.2015.9.2.423.

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This study was conducted on local sheep belongs to private flock in Erbil plain during the period 4/11/2011 till 25/10/2012. The investigation included 65 local sheep to study the effect of sex chromatinfrequency on the Daily Milk Yield (DMY), weight and age of ewes in addition the calculation ofRegression and Correlation coefficients between the studied traits of local sheep. The overall means offrequency of sex chromatin (drum stick, Appenx without stick, tear drop and small club). Appearedwith normal Neutrophils were 1.897, 1.034, 1.241, 0.741 and 95.86% respectively. The overall means ofDM
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Malhi, S. S., K. Heier, and E. Solberg. "Effectiveness of elemental S fertilizers on forage grass." Canadian Journal of Plant Science 80, no. 1 (2000): 105–12. http://dx.doi.org/10.4141/p99-002.

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Two field experiments were conducted from 1993 to 1995 to compare the effectiveness of various cumulative elemental S and sulphate-S fertilizer applications in increasing dry matter yield (DMY) and S uptake of forage grass. In exp. 1, one sulphate-S (Na2SO4) and two elemental S (Agric-Grade 0-0-0-95 and Tiger 90) fertilizers were applied annually to grass in mid to late April at 10, 20, 30, 40 and 50 kg S ha−1 rates. The increase in DMY from S application was significantly lower with elemental S fertilizers than with Na2SO4 in the first and second years, but in the third year elemental S ferti
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Ondřej, Cudlín, Hakl Josef, Hejcman Michal, and Cudlín Pavel. "The use of compressed height to estimate the yield of a differently fertilized meadow." Plant, Soil and Environment 64, No. 2 (2018): 76–81. http://dx.doi.org/10.17221/732/2017-pse.

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Monitoring of grassland dry matter yield (DMY) is important for the economy and ecosystem management, but it is a time-consuming process. Calculating the correlation between compressed height (CH) and DMY is a faster way to estimate DMY. The aim of our study was to use CH in order to predict DMY for a meadow with different fertilization management and plant species composition. Four fertilization treatments and one unfertilized control were established in a mesophilic meadow in the Czech Republic. Using a rising plate meter (RPM), CH was measured before the first and second cuts. In addition,
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Ma, Wei, Haiyun Liang, Keke He, et al. "Inhibitory Mechanisms of Vine Tea Extract and Dihydromyricetin Against Escherichia coli: A Multidimensional Analysis from Cell Membrane to Protein Synthesis." Foods 14, no. 12 (2025): 2011. https://doi.org/10.3390/foods14122011.

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Microbial contamination is the leading cause of foodborne diseases and spoilage in food and personal care products. Previous studies by our group have demonstrated that vine tea extract (VTE) and dihydromyricetin (DMY) inhibit the growth of Escherichia coli. In this study, we further explored the inhibitory mechanisms of VTE and DMY against E. coli through a label-free proteomics approach. The proteomic analysis detected 130 and 81 differentially expressed proteins (DEPs) in E.coli following VTE and DMY treatment, respectively. The analysis indicated that VTE and DMY inhibit bacterial growth t
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Chunlin, Ke, Dong Feng, and Wang Peirong. "Research on the Enhancement Mechanism of Dihydromyricetin on the Inhibitory Role of Cisplatin Towards Breast Cancer Cell Activity." Journal of Biomaterials and Tissue Engineering 12, no. 5 (2022): 989–95. http://dx.doi.org/10.1166/jbt.2022.2980.

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Objective: The purpose of our study was to evaluate Enhancement Mechanism of Dihydromyricetin (DMY) on the Inhibitory Role of Cisplatin Towards Breast Cancer Cell Activity. Materials and Methods: The MCF-7 were divided into NC, DMY, Cis and DMY+Cis groups. Using relative methods (MTT, TUNEL, Transwell, flow cytometry and wound healing) to evaluate MCF-7 cell biological activities including cell viability, apoptosis, invasion cell number and wound healing rate. The relative proteins expressions including FOXO-1, Noxa, Bim, Cyto C, Caspase-3, Caspase-9 and Apaf-1 were evaluated by WB assay. Resu
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Ye, Ling, Gendi Yin, Miaohua Jiang, Bo Tu, Zhicheng Li та Yiming Wang. "Dihydromyricetin Exhibits Antitumor Activity in Nasopharyngeal Cancer Cell Through Antagonizing Wnt/β-catenin Signaling". Integrative Cancer Therapies 20 (січень 2021): 153473542199121. http://dx.doi.org/10.1177/1534735421991217.

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Background: Cancer stem cells (CSCs) have been demonstrated to play a vital role in a diversity of biological processes in cancers. With the emergence of new evidence, the important function of CSCs in the formation of multidrug resistance of nasopharyngeal cancer has been demonstrated. Dysregulated Wnt/β-catenin signaling pathway is an important contributor to chemoresistance and maintenance of CSCs-like characteristics. This research aims to investigate comprehensively the function of dihydromyricetin (DMY), a natural flavonoid drug, on the cisplatin (cis) resistance and stem cell properties
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Wang, Renkai, Yanli Ren, Hafiz Umer Javad, Jieer Luo, Meng Zhou, and Xugang Shu. "Effect of Different Dietary Zinc Sources on Growth, Element Deposition, Antioxidation, Lipid Metabolism, and Related Gene Expression in Hybrid Grouper (♀ Epinephelus fuscoguttatus × ♂ E. lanceolatus)." Aquaculture Nutrition 2022 (August 12, 2022): 1–11. http://dx.doi.org/10.1155/2022/8371440.

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This study investigated the effect of different supplements of Zn on the growth performance, antioxidant, lipid metabolism, and element deposition of hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ E. lanceolatus). A total of 180 juvenile groupers (bodyweight 10.02 ± 0.01 g) were divided into three groups of 20 fish each and fed with ZnSO4, nanozinc oxide (Nano-ZnO), and dihydromyricetin-Zn (DMY-Zn) for 8 weeks(the content of Zn were 123,122.11, and 120.72 mg/kg). The findings revealed that DMY-Zn had a substantial impact on growth, feed conversion ratio, and protein efficiency ratio, whereas
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Huang, Wenbo, and Jing Xie. "Antibacterial Effect of Dihydromyricetin on Specific Spoilage Organisms of Hybrid Grouper." Journal of Food Quality 2021 (June 4, 2021): 1–11. http://dx.doi.org/10.1155/2021/5569298.

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This study aimed to investigate the mechanism of antibacterial activity level inhibition of dihydromyricetin (DMY) against specific spoilage bacteria of grouper. Firstly, the specific spoilage bacteria of grouper in the cold storage process are Pseudomonas antarctica (P. antarctica), which are selected by calculating the spoilage metabolite yield factor. It was determined that the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of DMY against grouper spoilage bacteria were 2.0 mg/mL and 6.4 mg/mL, respectively. DMY was added to the matrix of chitosan and sod
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Hanuš, Oto, Pavel Hering, Gustav Chládek, Daniel Falta, Petr Roubal, and Radoslava Jedelská. "Reliability of Milk Recording Data Under Conditions of Automatic Milking System." Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis 62, no. 5 (2014): 911–17. http://dx.doi.org/10.11118/actaun201462050911.

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Automatic milking system (AMS) brings a change in approach to ensure the data reliability in the official milk recording (MR). The AMS is equipped with flowmeter. AMS software provides the daily milk yield (DMY) and average of the last 7 daily milk yields (AVG7) for MR. Classic MR uses DMY. AVG7 could be more reliable value. Origin of both records (DMY and AVG7) is from AMS flowmeter. The aim of paper was to compare the values of milk yield of cows from daily (DMY) and the extended records (AVG7) from AMS for objective assess of lactations to be used in cattle breeding. Study (2013) with 2 AMS
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Santos, Vanderlei da Silva, Helcio Duarte Pereira, Juraci Souza Sampaio Filho, and Luciano Rogério Braatz de Andrade. "Genetic Merit of Parents and Heterosis in Cassava (Manihot esculenta Crantz)." Horticulturae 11, no. 7 (2025): 714. https://doi.org/10.3390/horticulturae11070714.

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Cassava breeders are led to discard plants before evaluating families, failing to obtain important information, such as the genetic merit of the parents. In this work, we evaluated a Clonal Evaluation Trial (CET) with 1886 clones from 57 crosses in an augmented block design with the 15 parents used as check treatments. We applied a mixed-model framework incorporating pedigree information. Three traits (fresh root yield (FRY), dry matter content (DMC) and dry matter yield (DMY)) were evaluated, and genetic gains considering several selection intensities were investigated. Disregarding the famil
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Chemere, Befekadu, Jiyung Kim, Baehun Lee, Moonju Kim, Byongwan Kim, and Kyungil Sung. "Detecting Long-Term Dry Matter Yield Trend of Sorghum-Sudangrass Hybrid and Climatic Factors Using Time Series Analysis in the Republic of Korea." Agriculture 8, no. 12 (2018): 197. http://dx.doi.org/10.3390/agriculture8120197.

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Despite the gradual increase in livestock feed demands, the supply faces enormous challenges due to extreme climatic conditions. As the presence of these climatic condition has the potential to affect the yield of sorghum-sudangrass hybrid (SSH), understanding the yield variation in relation to the climatic conditions provides the ability to come up with proper mitigation strategies. This study was designed to detect the effect of climatic factors on the long-term dry matter yield (DMY) trend of SSH using time series analysis in the Republic of Korea. The collected data consisted of DMY, seedi
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Zhao, Xufan, Yaqin Chen, Wenrui Zhang та ін. "Dihydromyricetin Inhibits Pseudorabies Virus Multiplication In Vitro by Regulating NF-κB Signaling Pathway and Apoptosis". Veterinary Sciences 10, № 2 (2023): 111. http://dx.doi.org/10.3390/vetsci10020111.

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Pseudorabies virus (PRV) infections have caused huge economic losses to the breeding industry worldwide, especially pig husbandry. PRV could threaten human health as an easily ignored zoonotic pathogen. The emergence of new mutants significantly reduced the protective effect of vaccination, indicating an urgent need to develop specific therapeutic drugs for PRV infection. In this study, we found that dihydromyricetin (DMY) could dose-dependently restrain PRV infection in vitro with an IC50 of 161.34 μM; the inhibition rate of DMY at a concentration of 500 μM was 92.16 %. Moreover, the mode of
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Gao, Ying, Hao Wu, Yanqun Luo, Xiaoliang Deng, Junming Chen, and Tao Wu. "Mechanisms of Dihydromyricetin for Improving Hepatic Fibrosis through the Integration of Metabolomics and Gut Microbiota." American Journal of Chinese Medicine 53, no. 03 (2025): 889–908. https://doi.org/10.1142/s0192415x25500338.

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It is crucial to prevent and treat liver fibrosis in patients with chronic liver disease. Dihydromyricetin (DMY) is a natural flavonoid compound from traditional Chinese medicine, known to alleviate chronic liver injury. However, its role in regulating inflammatory responses through gut microbiota and metabolic changes remains unclear. In this study, a mouse model of liver fibrosis was induced with carbon tetrachloride (CCl4), and DMY was administered via gavage. Histopathology, immunohistochemistry, Reverse Transcription Polymerase Chain Reaction (RT-PCR), 16S rRNA sequencing, and untargeted
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Fan, Lanlan, Xiaosheng Qu, Tao Yi, et al. "Metabolomics of the Protective Effect of Ampelopsis grossedentata and Its Major Active Compound Dihydromyricetin on the Liver of High-Fat Diet Hamster." Evidence-Based Complementary and Alternative Medicine 2020 (January 28, 2020): 1–15. http://dx.doi.org/10.1155/2020/3472578.

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The flavonoid dihydromyricetin (DMY) is the main component of Ampelopsis grossedentata (Hand-Mazz) W. T. Wang (AG), a daily beverage and folk medicine used in Southern China to treat jaundice hepatitis, cold fever, and sore throat. Recently, DMY and AG were shown to have a beneficial effect on lipid metabolism disorder. However, the mechanisms of how DMY and AG protect the liver during lipid metabolism disorder remain unclear. In this study, we first analyzed the chemical compounds of AG by HPLC-DAD-ESI-IT-TOF-MSn. Of the 31 compounds detected, 29 were identified based on previous results. The
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Xu, Qixia, Zi Li, Zhirui Jiang, Judith Campisi, and Yu Sun. "Abstract 2963: Dihydromyricetin is a senomorphic agent to promote therapeutic outcome of age-related conditions including cancer and Alzheimer's disease." Cancer Research 84, no. 6_Supplement (2024): 2963. http://dx.doi.org/10.1158/1538-7445.am2024-2963.

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Abstract Aging is characterized by a progressive decline of organ function and gradual rise of susceptibility to multiple chronic disorders, with cancer being a primary cause of human morbidity and mortality worldwide. Cellular senescence represents a state of permanent cell cycle arrest and contributes to chronological aging and age-related diseases including Alzheimer's disease (AD), mainly through development of a distinct secretome termed the senescence-associated secretory phenotype (SASP). By screening a natural medicinal agent library, we noticed Rattan tea extract (RTE) has a prominent
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Raoof, Salim Omar, دلياك بيرخدر, and Younis Ahmad SheakhMohamad. "Role of Sex Chromatin on Performance in the Crossbred Cows." Journal of Biotechnology Research Center 10, no. 2 (2016): 6–11. http://dx.doi.org/10.24126/jobrc.2016.10.2.472.

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This study was conducted on a total of 67crossbred cows in Erbil plain during the period from July/ 2014 to April / 2015, to study the role of sex chromatin shapes (Drum stick, Sessile nodule, Tear drop and Small club) on Daily Milk Yield (DMY), Lactation Period(LP), fertility rate and fertilize estrous sequences. We also study the effect of age of cows on the DMY, LP, and fertility and fertilize estrous sequences. The overall means of sex chromatin shapes drum stick, sessile nodule, tear drop shape and small club were 25.0 %, 35.0 %, 22.0 % and 18.0%, respectively. While the overall means of
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Si, Xiaojing, Yue Huang, Mei Han, and Liqiang Luo. "Electrochemical Sensor Based on Co-MOF for the Detection of Dihydromyricetin in Ampelopsis grossedentata." Molecules 30, no. 1 (2025): 180. https://doi.org/10.3390/molecules30010180.

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Dihydromyricetin (DMY), as the main active ingredient in Ampelopsis grossedentata, is a naturally occurring flavonoid that has attracted extensive attention for its multiple biological activities. For the quick and accurate measurement of DMY, a novel electrochemical sensor based on a glassy carbon electrode (GCE) modified with a cobalt metal-organic framework (Co-MOF) was proposed in this work. The Co-MOF was synthesized via a single-step hydrothermal process using Co(NO3)2·6H2O. Fourier infrared spectroscopy, X-ray photoelectron spectroscopy and scanning electron microscopy were used to stud
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Neder, Diogo Gonçalves, Fabiane Rabelo da Costa, Ricardo Loiola Edvan, and Lenildo Teixeira Souto Filho. "Correlations and path analysis of morphological and yield traits of cactus pear accessions." Crop Breeding and Applied Biotechnology 13, no. 3 (2013): 203–7. http://dx.doi.org/10.1590/s1984-70332013000300009.

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The objectives of this study were to evaluate the relationships between morphological characteristics and fresh matter yield of cactus pear and identify their direct and indirect effects. Nineteen accessions were evaluated for the following traits: number (NCl), thickness (ThCl), length (LCl) and width (WCl) of cladodes, plant height (PH) and plant width (PW), and green matter yield (GMY), dry matter yield (DMY) and dry matter percentage (DM). The correlations were estimated, and path analysis was performed by the method proposed by Wright. GMY was strongly correlated with DMY, allowing indire
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Tawfik, E. S., M. K. Mohsen, A. Y. Salem, and H. G. El-Awady. "Study on Friesian Herds Raised in Egypt and Germany – I. Estimate of non-genetic effects and genetic parameters." Archives Animal Breeding 43, no. 2 (2000): 101–14. http://dx.doi.org/10.5194/aab-43-101-2000.

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Abstract. Data on 2422 and 27756 Friesian cows in Egypt and Germany, respectively, were used to estimate genetic and non-genetic effects on initial milk yield in 70 days (IMY), 305-day milk yield (305-dMY), lactation period (LP) and calving interval (CI). Data were collected in the period from 1987 to 1992 in Egypt and from 1979 to 1993 in Germany. Least Squares analysis shows the significant effect of season and year of calving and parity on all traits. Least Squares analysis indicates that winter and spring calvers had the higher value in all traits studied than summer and autumn calvers of
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45

Foster, Allan, and Bill Biligetu. "Effect of harvest date and frequency on aspen ricegrass (Oryzopsis asperifolia) and cream-coloured vetchling (Lathyrus ochroleucus) in the boreal transition ecoregion of Saskatchewan." Canadian Journal of Plant Science 98, no. 5 (2018): 1133–38. http://dx.doi.org/10.1139/cjps-2017-0332.

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Aspen forest communities of Saskatchewan, Canada, support a significant cattle population. The objectives of this study were to determine seasonal forage dry matter (DM) accumulation and evaluate repeated annual defoliation on DM yield (DMY) of aspen ricegrass (Oryzopsis asperifolia) and cream-coloured vetchling (Lathyrus ochroleucus) in the boreal transition ecoregion of east–central Saskatchewan. The experimental design was a randomized completed block with five replicates. Seasonal DMY of aspen ricegrass (p < 0.0001) was lowest in June, intermediate in July, and highest in August to Octo
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McCaughey, W. P., and R. G. Simons. "Harvest management and N-fertilization effects on yield and regrowth of smooth bromegrass, crested wheatgrass, and meadow bromegrass in the eastern prairies." Canadian Journal of Plant Science 76, no. 4 (1996): 773–82. http://dx.doi.org/10.4141/cjps96-130.

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Little information exists describing how pasture-type grasses such as meadow bromegrass (Bromus biebersteinii Roem & Schult.; MBR) may differ from hay-type grasses such as crested wheatgrass (Agropyron cristatum (L.) Gaertn.; CWG) and smooth bromegrass (Bromus inermis Leyss.; SBR) in terms of DMY response to harvest and fertilizer management. In a 3-yr field trial at Brandon, MB harvest management (two-cut hay management or three- to four-cut simulated pasture management) and nitrogen fertilizer (0, 40, 80, 120, 160 kg N ha−1) were examined for their interactive effects on DMY and percent
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Mirahki, Isaac, Mohammad Reza Ardakani, Farid Golzardi, Farzad Paknejad, and Ali Mahrokh. "Biomass production, water use efficiency and nutritional value parameters of sorghum (Sorghum bicolor L.) genotypes as affected by seed hydro-priming and transplanting." Acta Biologica Szegediensis 2, no. 65 (2022): 171–84. http://dx.doi.org/10.14232/abs.2021.65.171-184.

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To investigate hydropriming and transplanting effect on biomass and nutritional content of forage sorghum, a two-year field experiment was conducted in the semiarid condition of Iran. Experimental factor consisted of planting dates (July-1st, July-11th, July-23rd, August-1st) in the main plot and the factorial combination of planting methods (direct planting, hydropriming, transplanting) with cultivars (Speedfeed and Pegah) in the subplot. Planting date postponement from 1st of July to 10th of July, 23rd of July, and 1st of August, respectively, caused 16.1, 32.5 and 47.2% reduction in dry mat
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Yang, Dafeng, Shenglan Tan, Zhousheng Yang та ін. "Dihydromyricetin Attenuates TNF-α-Induced Endothelial Dysfunction through miR-21-Mediated DDAH1/ADMA/NO Signal Pathway". BioMed Research International 2018 (2018): 1–12. http://dx.doi.org/10.1155/2018/1047810.

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Accumulating studies demonstrate that dihydromyricetin (DMY), a compound extracted from Chinese traditional herb, Ampelopsis grossedentata, attenuates atherosclerotic process by improvement of endothelial dysfunction. However, the underlying mechanism remains poorly understood. Thus, the aim of this study is to investigate the potential mechanism behind the attenuating effects of DMY on tumor necrosis factor alpha- (TNF-α-) induced endothelial dysfunction. In response to TNF-α, microRNA-21 (miR-21) expression was significantly increased in human umbilical vein endothelial cells (HUVECs), in li
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BEHERA, RAJALAXMI, A. K. CHAKRAVARTY, N. KASHYAP, et al. "Identification of most suitable temperature humidity index model for daily milk yield of Murrah buffaloes in subtropical climatic condition of India." Indian Journal of Animal Sciences 88, no. 7 (2018): 834–37. http://dx.doi.org/10.56093/ijans.v88i7.81477.

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The present study was carried out to identify the most suitable temperature humidity index (THI model) among seven reported THI models as heat stress indicator on daily milk yield (DMY) of Murrah buffaloes at subtropical climatic conditions of Karnal, India. A total of 302,101 daily milk yield records from 1,434 lactational milk yield records and pedigree records of 748 buffaloes belonging to five parities spanned over a period of about 20 years (March 1994-December 2013) were obtained from ICAR-NDRI, Karnal and weather information on dry bulb temperature (Tdb), wet bulb temperature (Twb) and
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50

Mirahki, Isaac, Mohammad Reza Ardakani, Farid Golzardi, Farzad Paknejad, and Ali Mahrokh. "Biomass production, water use efficiency and nutritional value parameters of sorghum ( Sorghum bicolor L.) genotypes as affected by seed hydro-priming and transplanting." Acta Biologica Szegediensis 2, no. 65 (2022): 171–84. http://dx.doi.org/10.14232/abs.2021.2.171-184.

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To investigate hydropriming and transplanting effect on biomass and nutritional content of forage sorghum, a two-year field experiment was conducted in the semiarid condition of Iran. Experimental factor consisted of planting dates (July-1st, July-11th, July-23rd, August-1st) in the main plot and the factorial combination of planting methods (direct planting, hydropriming, transplanting) with cultivars (Speedfeed and Pegah) in the subplot. Planting date postponement from 1st of July to 10th of July, 23rd of July, and 1st of August, respectively, caused 16.1, 32.5 and 47.2% reduction in dry mat
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