Academic literature on the topic 'DNA and RNA sampling'

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Journal articles on the topic "DNA and RNA sampling"

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Maass, Kendra K., Paulina S. Schad, Agnes M. E. Finster, et al. "From Sampling to Sequencing: A Liquid Biopsy Pre-Analytic Workflow to Maximize Multi-Layer Genomic Information from a Single Tube." Cancers 13, no. 12 (2021): 3002. http://dx.doi.org/10.3390/cancers13123002.

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Liquid biopsies hold great promise for the management of cancer. Reliable liquid biopsy data depend on stable and reproducible pre-analytical protocols that comply with quality measures, irrespective of the sampling and processing site. We established a workflow for plasma preservation, followed by processing, cell-free nucleic acid isolation, quantification, and enrichment of potentially tumor-derived cell-free DNA and RNA. Employing the same input material for a direct comparison of different kits and protocols allowed us to formulate unbiased recommendations for sample collection, storage,
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Shim, Hyunjin. "NAD: Noise-augmented direct sequencing of target nucleic acids by augmenting with noise and selective sampling." F1000Research 14 (April 10, 2025): 423. https://doi.org/10.12688/f1000research.163516.1.

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Background Next-generation sequencing necessitates a minimum quantity and concentration of DNA/RNA samples, typically achieved through amplification using the PCR technique. However, this amplification step introduces several drawbacks to biological insights, including PCR bias and the loss of epigenetic information. The advent of long-read sequencing technologies facilitates direct sequencing, with the primary constraint being the limited amount of DNA/RNA present in biological samples. Methods Here, we present a novel method called Noise-Augmented Direct (NAD) sequencing that enables the dir
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Liu, Jun, and Ning Gao. "Impact of sample characteristics on RNA-based next-generation sequencing (NGS) for fusion gene detection in non-small cell lung cancer (NSCLC)." Journal of Clinical Oncology 43, no. 16_suppl (2025): 3132. https://doi.org/10.1200/jco.2025.43.16_suppl.3132.

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3132 Background: RNA-based next-generation sequencing (NGS) has been widely employed for detecting fusion genes in NSCLC, due to its superior sensitivity and simplified design compared to DNA-based NGS. However, the impact of sample quality on fusion variant detection using RNA-based NGS remains unclear. Methods: The study analyzed 5,386 and 5,538 NSCLC samples using DNA- or RNA-based NGS to detect common fusion genes (ALK, RET, ROS1, NTRK, NRG1, MET exon 14 skipping, and FGFR). NGS libraries were constructed using capture-based or amplicon-based methods for DNA and RNA samples, respectively,
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Chu, T. Y., K. S. Hwang, M. H. Yu, H. S. Lee, H. C. Lai, and J. Y. Liu. "A research-based tumor tissue bank of gynecologic oncology: characteristics of nucleic acids extracted from normal and tumor tissues from different sites." International Journal of Gynecologic Cancer 12, no. 2 (2002): 171–76. http://dx.doi.org/10.1136/ijgc-00009577-200203000-00006.

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This article describes a gynecology and pathology-oriented tumor tissue bank that is approaching the research requirements of modern molecular oncology and compared characteristics of nucleic acids extracted from preserved tissues. Through August 2000, 8869 specimens, including fresh neoplastic tissues and normal counterparts, body fluids (ascites, tumor content, and blood), and cervical scrapings, were procured from 1853 patients. DNA and RNA were extracted from a random sampling of normal (n= 50) and tumor (n= 53) tissues from the uterine cervix (n= 47), endometrium (n= 24), and ovary (n= 32
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Kapadia, Jay Bhakti, Nawwaf Kharma, Alen Nellikulam Davis, Nicolas Kamel, and Jonathan Perreault. "Toehold-mediated strand displacement to measure released product from self-cleaving ribozymes." RNA 28, no. 2 (2021): 263–73. http://dx.doi.org/10.1261/rna.078823.121.

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This paper presents a probe comprising a fluorophore and a quencher, enabling measurement of released product from self-cleaving hammerhead ribozyme, without labeled RNA molecules, regular sampling or use of polyacrylamide gels. The probe is made of two DNA strands; one strand is labeled with a fluorophore at its 5′-end, while the other strand is labeled with a quencher at its 3′-end. These two DNA strands are perfectly complementary, but with a 3′-overhang of the fluorophore strand. These unpaired nucleotides act as a toehold, which is utilized by a detached cleaved fragment (coming from a se
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Martell, Danya J., Chandra P. Joshi, Ahmed Gaballa, et al. "Metalloregulator CueR biases RNA polymerase’s kinetic sampling of dead-end or open complex to repress or activate transcription." Proceedings of the National Academy of Sciences 112, no. 44 (2015): 13467–72. http://dx.doi.org/10.1073/pnas.1515231112.

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Metalloregulators respond to metal ions to regulate transcription of metal homeostasis genes. MerR-family metalloregulators act on σ70-dependent suboptimal promoters and operate via a unique DNA distortion mechanism in which both the apo and holo forms of the regulators bind tightly to their operator sequence, distorting DNA structure and leading to transcription repression or activation, respectively. It remains unclear how these metalloregulator−DNA interactions are coupled dynamically to RNA polymerase (RNAP) interactions with DNA for transcription regulation. Using single-molecule FRET, we
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Lin, Lynlee L., Tarl W. Prow, Anthony P. Raphael, et al. "Microbiopsy engineered for minimally invasive and suture-free sub-millimetre skin sampling." F1000Research 2 (May 2, 2013): 120. http://dx.doi.org/10.12688/f1000research.2-120.v1.

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We describe the development of a sub-millimetre skin punch biopsy device for painless and suture-free skin sampling for molecular diagnosis and research. Conventional skin punch biopsies range from 2-4 mm in diameter. Local anaesthesia is required and sutures are usually used to close the wound. Our microbiopsy is 0.50 mm wide and 0.20 mm thick. The microbiopsy device is fabricated from three stacked medical grade stainless steel plates tapered to a point and contains a chamber within the centre plate to collect the skin sample. We observed that the application of this device resulted in a 0.2
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Lin, Lynlee L., Tarl W. Prow, Anthony P. Raphael, et al. "Microbiopsy engineered for minimally invasive and suture-free sub-millimetre skin sampling." F1000Research 2 (July 31, 2013): 120. http://dx.doi.org/10.12688/f1000research.2-120.v2.

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We describe the development of a sub-millimetre skin punch biopsy device for minimally invasive and suture-free skin sampling for molecular diagnosis and research. Conventional skin punch biopsies range from 2-4 mm in diameter. Local anaesthesia is required and sutures are usually used to close the wound. Our microbiopsy is 0.50 mm wide and 0.20 mm thick. The microbiopsy device is fabricated from three stacked medical grade stainless steel plates tapered to a point and contains a chamber within the centre plate to collect the skin sample. We observed that the application of this device resulte
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Porter, Ashleigh F., Mang Shi, John-Sebastian Eden, Yong-Zhen Zhang, and Edward C. Holmes. "Diversity and Evolution of Novel Invertebrate DNA Viruses Revealed by Meta-Transcriptomics." Viruses 11, no. 12 (2019): 1092. http://dx.doi.org/10.3390/v11121092.

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DNA viruses comprise a wide array of genome structures and infect diverse host species. To date, most studies of DNA viruses have focused on those with the strongest disease associations. Accordingly, there has been a marked lack of sampling of DNA viruses from invertebrates. Bulk RNA sequencing has resulted in the discovery of a myriad of novel RNA viruses, and herein we used this methodology to identify actively transcribing DNA viruses in meta-transcriptomic libraries of diverse invertebrate species. Our analysis revealed high levels of phylogenetic diversity in DNA viruses, including 13 sp
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Vasudevan, Harish, Abrar Choudhury, Stephanie Hilz, et al. "PATH-36. INTRATUMOR HETEROGENEITY AND BIOINFORMATIC DIFFERENCES INFLUENCE MENINGIOMA MOLECULAR CLASSIFICATION." Neuro-Oncology 23, Supplement_6 (2021): vi123. http://dx.doi.org/10.1093/neuonc/noab196.488.

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Abstract Molecular alterations such as CDKN2A inactivation and TERT promoter mutation are new criteria for grade 3 meningiomas in the 5th edition of the WHO Classification of Tumors of the Central Nervous System. However, consensus approaches to identify copy number variants (CNVs) and short somatic variants in meningiomas are lacking. Here, we performed integrated DNA methylation profiling, RNA-sequencing, and targeted DNA mutational profiling on 10 stereotactically-collected, regionally-distinct samples from 4 meningiomas. Targeted DNA sequencing revealed numerous private short somatic varia
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Dissertations / Theses on the topic "DNA and RNA sampling"

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Michalik, Juraj. "Non-redundant sampling in RNA Bioinformatics." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLX009/document.

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Un échantillonnage statistique est central à de nombreuses méthodes algorithmiques pour la bioinformatique structurale des ARNs, où ils sont couramment utilisés pour identifier des modèles structuraux importants, fournir des résumés des espaces de repliement ou approcher des quantités d'intérêt dans l'équilibre thermodynamique. Dans tous ces exemples, la redondance dans l'ensemble échantillonné est non-informative et inefficace, limitant la portée des applications des méthodes existantes. Dans cette thèse, nous introduisons le concept de l'échantillonnage non-redondante et nous explorons ses a
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Gil, Ley Alejandro. "Enhanced sampling and force field corrections for RNA oligomers." Doctoral thesis, SISSA, 2016. http://hdl.handle.net/20.500.11767/4628.

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The computational study of conformational transitions in nucleic acids still faces many challenges. For example, in the case of single stranded RNA tetranucleotides, agreement between simulations and experiments is not satisfactory due to inaccuracies in the force fields commonly used in molecular dynamics. Improvement of force fields is however hindered by the diiculties of decoupling those errors from the statistical errors caused by insuicient sampling. We here tackle both problems by introducing a novel enhancing sampling method and using experimental data to improve RNA force fields. In t
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Buttner, M. "RNA polymerase - DNA interactions in Streptomyces." Thesis, University of Bristol, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.354445.

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Nandakumar, Jayakrishnan. "Discrimination of RNA versus DNA by an RNA ligase and distinct modes of substrate recognition by DNA ligases /." Access full-text from WCMC:, 2007. http://proquest.umi.com/pqdweb?did=1428838891&sid=13&Fmt=2&clientId=8424&RQT=309&VName=PQD.

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Gilea, Manuela Aurora. "DNA and RNA synthesis in ionic liquids." Thesis, Queen's University Belfast, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485198.

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The solid-phase synthesis of oligonucleotide derivatives such as phosphorothioates and phosphoroselenoates was investigated. Some ionic liquids containing the trlbexyl(tetradecyl)phosphonium cation and various anions proved to be very effective in dissolving the chalcogens (sulfur and , selenium) and to prepare oligonucleoside chalcogenophosphates. The suitability ofionic liquid-based chalcogen-transfer mixtures for the synthesis of oligonucleoside chalcogenophosphates on solid-phase was evaluated and subsequently the structure-activity relationship studied in detail. The compatibility of ioni
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Antson, Dan-Oscar. "Genotyping RNA and DNA using padlock probes." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-5057-1/.

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Zhu, Jian. "The stabilities of RNA and DNA structural elements." Diss., Georgia Institute of Technology, 1998. http://hdl.handle.net/1853/25194.

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Hill, G. R. "NMR studies of DNA and RNA binding proteins." Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604060.

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HMG-D is a 112-residue, non-histone chromosomal protein from <i>Drosophila melanogaster </i>and is a member of the class of non-sequence specific HMGB proteins. The present project was based on the observation that other HMGB complexes that had been solved by NMR had a phenylalanine residue at a key interfacial location (corresponding to position 12 in HMG-D), whereas those like HMG-D that gave few intermolecular NOE cross peaks generally had a tyrosine at this location. This tyrosine was known to be involved in hydrogen-bonding to the DNA in a related complex that had been solved crystallogra
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O'Hanlon, Karen Ann. "Studies on the enzyme DNA-dependent RNA polymerase." Thesis, University of Reading, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266340.

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Pritchard, Hannah Louise. "Recognition agents for DNA and RNA quadruplex structures." Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/5727/.

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The design and synthesis of a new class of G-quadruplex DNA recognition agents are discussed in this thesis along with their binding abilities to both duplex and G-quadruplex forming DNA. A selection of G-quadruplex binders reported in the literature to date have been reviewed and their interactions with the quadruplex DNA structure analysed. The biisoquinoline ligand used to incorporate into the metal complexes synthesised in this thesis was chosen because of its large aromatic surface area which is ideal for end stacking onto G-quartets. Both the palladium and platinum biisoquinoline complex
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Books on the topic "DNA and RNA sampling"

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Smith, Harold C., ed. RNA and DNA Editing. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470262269.

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Erdmann, Volker A., Stefan Jurga, and Jan Barciszewski, eds. RNA and DNA Diagnostics. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-17305-4.

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Sinkovics, Joseph G. RNA/DNA and Cancer. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-22279-0.

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Aphasizhev, Ruslan, ed. RNA and DNA Editing. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-018-8.

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A, Melton Douglas, and Cold Spring Harbor Laboratory, eds. Antisense RNA and DNA. Cold Spring Harbor Laboratory, 1988.

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Valero, Julián, ed. DNA and RNA Origami. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3028-0.

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H, Murray James A., ed. Antisense RNA and DNA. Wiley-Liss, 1992.

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Harwood, Adrian J. Basic DNA and RNA Protocols. Humana Press, 1996. http://dx.doi.org/10.1385/089603402x.

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Anders, Hans-Joachim, and Adriana Migliorini, eds. Innate DNA and RNA Recognition. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-0882-0.

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J, Harwood Adrian, ed. Basic DNA and RNA protocols. Humana Press, 1996.

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Book chapters on the topic "DNA and RNA sampling"

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Goddard, William A. "DNA-RNA." In Computational Materials, Chemistry, and Biochemistry: From Bold Initiatives to the Last Mile. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-18778-1_69.

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Arnemann, J. "DNA-/RNA-Konzentrationsbestimmung." In Springer Reference Medizin. Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_3464.

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Arnemann, J. "DNA-/RNA-Konzentrationsbestimmung." In Lexikon der Medizinischen Laboratoriumsdiagnostik. Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-49054-9_3464-1.

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Piro, Benoît, Vincent Noël, and Steeve Reisberg. "DNA and PNA Probes for DNA Detection in Electroanalytical Systems." In RNA Technologies. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-17305-4_3.

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Landweber, Laura. "RNA based computing: Some examples from RNA catalysis and RNA editing." In DNA Based Computers II. American Mathematical Society, 1998. http://dx.doi.org/10.1090/dimacs/044/15.

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Hoehn, Sean J., Naishka E. Caldero-Rodríguez, and Carlos E. Crespo-Hernández. "CHAPTER 9. Photochemistry of RNA, RNA Monomers, and Plausible Prebiotic Precursors." In DNA Photodamage. Royal Society of Chemistry, 2021. http://dx.doi.org/10.1039/9781839165580-00197.

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Kular, Lara, and Maja Jagodic. "DNA Methylation in Multiple Sclerosis." In RNA Technologies. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-14792-1_8.

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Lu, Shuhan, Ying Zhang, and Hao Yin. "Chimeric DNA–RNA Guide RNA Designs." In Methods in Molecular Biology. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0687-2_6.

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Ulmer, Jeffrey B. "DNA Vaccines Against RNA Viruses." In DNA Vaccines. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4615-0105-3_7.

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Noel, Vincent, Benoit Piro, and Steeve Reisberg. "DNA for Non-nucleic Acid Sensing." In RNA Technologies. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-17305-4_4.

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Conference papers on the topic "DNA and RNA sampling"

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De Paula, Renato, Cruz St Peter, Ian Alex Richardson, et al. "DNA Sequencing of Oilfield Samples: Impact of Protocol Choices on the Microbiological Conclusions." In CORROSION 2018. NACE International, 2018. https://doi.org/10.5006/c2018-11662.

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Abstract In the last decade, molecular microbiology techniques have significantly expanded the understanding of the resident microflora in hydrocarbon reservoirs and production systems. These methods have been steadily accepted by the industry and are widely viewed as accurate, comprehensive and highly valuable tools that augment or may eventually replace conventional methods. The resulting information has helped operators and service companies to develop better monitoring programs, assess risks and tailor mitigation strategies to control undesired microbial activities in wells, flowlines and
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Triananda, Gregory, Dylan Febrian, Bakti Amirul Jabar, Fredy Purnomo, and Simeon Yuda Prasetyo. "Use of Deep Learning to Identify COVID-19 through DNA/RNA Sequencing." In 2024 4th International Conference on Electronic and Electrical Engineering and Intelligent System (ICE3IS). IEEE, 2024. https://doi.org/10.1109/ice3is62977.2024.10775533.

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Anika, Niranjana S, Prerna Kriti, Sumathra M, and A. H. Manjunath Reddy. "Fluorescent Nucleic Acid Biosensors: A Comparative Study of DNA and RNA-Based Sensing Platforms." In 2024 8th International Conference on Computational System and Information Technology for Sustainable Solutions (CSITSS). IEEE, 2024. https://doi.org/10.1109/csitss64042.2024.10816759.

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Whulanza, Yudan, Andriko Indriantomo, Cosmas Nurdiyantoko, and Ridho Irwansyah. "Characterisation of Microfluidic Systems for Automated Extraction Device of DNA Sampling." In Seminar Nasional Tahunan Teknik Mesin XXII 2024. Badan Kerja Sama Teknik Mesin Indonesia, 2025. https://doi.org/10.71452/590886.

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Engels, Joachim W., Thomas J. Lehmann, Jörg Parsch, and Thorsten Strube. "Fluorine substituted DNA and RNA." In XIIth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2002. http://dx.doi.org/10.1135/css200205245.

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Joby, George, K. Vrinda, Govindan Chandana, Surendran Arundhathy, and Biju Avany. "DNA RNA binding protein prediction." In MULTIMEDIA UNIVERSITY ENGINEERING CONFERENCE 2023 (MECON2023). AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0230564.

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Oktaviani, Deti Astrit, Mohamad Zulman Hakim, and Dirvi Surya Abbas. "Pengaruh Leverage, Profitabilitas, Ukuran Perusahaan, Dan Likuiditas Terhadap Tax Avoidance." In SEMINAR NASIONAL DAN CALL FOR PAPER 2020 FAKULTAS EKONOMI DAN BISNIS UNIVERSITAS MUHAMMADIYAH JEMBER. UM Jember Press, 2021. http://dx.doi.org/10.32528/psneb.v0i0.5195.

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Tujuan dari penelitian ini untuk mengetahui pengaruh leverage (DER), Profitabilitas (ROA), Ukuran perusahaan (SIZE), dan Likuiditas (CR) terhadap Tax Avoidance. Dengan variable dependen tax avoidance yang di proksikann kepada CETR (Cash Effective Tax Rate). Populasi dalam penelitian ini meliputi seluruh perusahaan Food and Beverage yang terdaftar di Bursa Efek Indonesia (BEI) pada tahun 2017 – 2019 yang berjumlah 24 perusahaan dengan menggunakan purposive sampling diperoleh 17 perusahaan yang memenuhi kriteria, dengan jumlah data observasi sebanyak 51 data. Penelitian ini menggunakan analisis
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Galitsyna, Aleksandra, Anastasia Zharikova, Maria Logacheva, Sergey Razin, Andrey Mironov, and Alexey Gavrilov. "Large-scale analysis of RNA-DNA interactions." In 2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2018. http://dx.doi.org/10.1109/bibm.2018.8621137.

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Fang, Xiaohong, Sheldon Schuster, Xiaojing Liu, et al. "Molecular beacon biosensors for DNA/RNA analysis." In BiOS 2000 The International Symposium on Biomedical Optics, edited by Patrick A. Limbach, John C. Owicki, Ramesh Raghavachari, and Weihong Tan. SPIE, 2000. http://dx.doi.org/10.1117/12.380499.

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Bielińska-Wa̧ż, D., P. Wa̧ż, W. Nowak, et al. "Similarity and Dissimilarity of DNA∕RNA Sequences." In COMPUTATIONAL METHODS IN SCIENCE AND ENGINEERING: Theory and Computation: Old Problems and New Challenges. Lectures Presented at the International Conference on Computational Methods in Science and Engineering 2007 (ICCMSE 2007): VOLUME 1. AIP, 2007. http://dx.doi.org/10.1063/1.2836064.

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Reports on the topic "DNA and RNA sampling"

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Fang, Wenwen. RNA-Guided DNA Rearrangements in Breast Cancer. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada574382.

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Dr. Boris Fain. Collective motion sampling in proteins and DNA. Office of Scientific and Technical Information (OSTI), 2000. http://dx.doi.org/10.2172/765120.

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Dugan, L. Elucidation of the Mechanism of Gene Silencing using Small Interferin RNA: DNA Hybrid Molecules. Office of Scientific and Technical Information (OSTI), 2006. http://dx.doi.org/10.2172/900164.

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Laurence, Jeffrey. Antibody to the RNA-Dependent DNA Polymerase of HTLV-III: Characterization and Clinical Associations. Defense Technical Information Center, 1990. http://dx.doi.org/10.21236/ada231466.

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Laurence, Jeffrey. Antibody to the RNA-Dependent DNA Polymerase of HTLV-III: characterization and Clinical Associations. Defense Technical Information Center, 1988. http://dx.doi.org/10.21236/ada227404.

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Laurence, Jeffrey. Antibody to the RNA-Dependent DNA Polymerase of HTLV-III: characterization and Clinical Associations. Defense Technical Information Center, 1988. http://dx.doi.org/10.21236/ada227519.

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Gal-On, Amit, Shou-Wei Ding, Victor P. Gaba, and Harry S. Paris. role of RNA-dependent RNA polymerase 1 in plant virus defense. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7597919.bard.

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Objectives: Our BARD proposal on the impact of RNA-dependent RNA polymerase 1 (RDR1) in plant defense against viruses was divided into four original objectives. 1. To examine whether a high level of dsRNA expression can stimulate RDR1 transcription independent of salicylic acid (SA) concentration. 2. To determine whether the high or low level of RDR1 transcript accumulation observed in virus resistant and susceptible cultivars is associated with viral resistance and susceptibility. 3. To define the biogenesis and function of RDR1-dependent endogenous siRNAs. 4. To understand why Cucumber mosai
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Hingerty, B. DUPLEX: A molecular mechanics program in torsion angle space for computing structures of DNA and RNA. Office of Scientific and Technical Information (OSTI), 1992. http://dx.doi.org/10.2172/7250412.

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Hingerty, B. DUPLEX: A molecular mechanics program in torsion angle space for computing structures of DNA and RNA. Office of Scientific and Technical Information (OSTI), 1992. http://dx.doi.org/10.2172/10179029.

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Research, Gratis. Vaccines Through History: Smallpox to COVID-19. Gratis Research, 2021. http://dx.doi.org/10.47496/gr.blog.011.

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More recently, as genomes turned out to be promptly decodable, scientists have developed proficient knowledge at developing vaccines that depend on extraction of RNA or DNA from microbes and injecting these into the body.
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