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Dissertations / Theses on the topic 'DNA; Chromosomes'

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1

Dunn, Alison M. "Cloning of human DNA repair genes." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301385.

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2

Fielder, Anne. "A structural role for the H-NS protein in bacterial chromatin." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308709.

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3

Yu, Zhiling. "Interactions and architecture of human MCM proteins in vitro and in vivo /." View Abstract or Full-Text, 2003. http://library.ust.hk/cgi/db/thesis.pl?BICH%202003%20YU.

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Thesis (Ph. D.)--Hong Kong University of Science and Technology, 2003.<br>Includes bibliographical references (leaves 118-137). Also available in electronic version. Access restricted to campus users.
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4

Rudd, Mary Katharine. "Organization, evolution and function of alpha satellite DNA at human centromeres." Case Western Reserve University School of Graduate Studies / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=case1091493781.

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5

Ramos, Edward. "Tools for studying gross nuclear organization, dynamics and epigenetic modifications of chromosomes /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/10849.

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6

Bauer, David L. V. "Preparing and sequencing ultra-long DNA molecules from single chromosomes." Thesis, University of Oxford, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.640151.

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In this thesis, I describe the development of a single-molecule platform for analysing long DNA molecules that captures haplotype and large-scale structural variation (SV) in addition to DNA sequence. Cunent DNA sequencing methods cannot adequately examine haplotype and SV - both contribute to biological function and disease and are candidates for the location of "missing heritability" in the genome. Both haplotype and SV fundamentally relate to the structure of single chromosomes. Using a lab-on-a-chip nanofluidic device, SV was analysed on stretched (> 2 Mb) DNA fragments. In order to integr
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7

Spence, Jennifer M. "Repetitive DNA in aphids : its nature, chromosomal distribution and evolutionary significance." Thesis, University of Reading, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298517.

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8

Harvey, Alison Nichola. "The induction and production of chromosomal aberrations by restriction endonucleases." Thesis, Open University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.388300.

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9

Curwen, Gillian B. "G₂ chromosomal radiosensitivity in childhood and adolescent cancer survivors and their offspring." Thesis, St Andrews, 2008. http://hdl.handle.net/10023/425.

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10

Oakey, Rebecca. "The structure of alphoid satellite DNA on normal and abnormal human Y chromosomes." Thesis, University of Oxford, 1989. http://ora.ox.ac.uk/objects/uuid:162cb1a7-3176-4b56-be8b-353b65fee236.

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The long-range structure of the Y chromosome alphoid satellite DNA has been determined in the cell lines 3E7 and OXEN. Variation in alphoid DNA block size and restriction enzyme sites were observed. The alphoid block size and restriction enzyme site variations were determined for a collection of 42 normal Y chromosomes. The alphoid DNA polymorphisms observed denned 24 Y chromosome alleles. Unexpectedly, the Y alphoid DNA alleles analysed revealed two distinct groups of Y chromosomes indicating that most of the Caucasian and Asian men analysed were descended from one of two males. The structure
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11

Derive, Nicolas. "Etude du rôle et de la régulation de BubR1 dans la ségrégation des chromosomes acentriques." Thesis, Bordeaux, 2014. http://www.theses.fr/2014BORD0256/document.

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La transmission correcte du matériel génétique au cours de la mitose requiert l’attachement correct des chromosomes aux microtubules du fuseau mitotique. Les centromères au niveau des chromosomes servent de site d’assemblage aux kinétochores, interfaces multiprotéiques permettant la liaison des microtubules. Cependant, nous avons récemment mis en évidence chez la drosophile un mécanisme par lequel les fragments acentriques ségrégent normalement. Celui-­‐ci fonctionne grâce à un « tether », un filament d’ADN, qui relie les fragments acentriques à leurs partenaires centriques. L’intégrité du tet
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12

Thomas, Stephen W. "Molecular studies of homologous chromosome pairing in Triticum aestivum /." Title page, table of contents and abstract only, 1997. http://web4.library.adelaide.edu.au/theses/09PH/09pht462.pdf.

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13

Van, Brabant Anja Josifa. "Characterizing YAC replication : identification and deletion of replication origins within a human DNA insert /." Thesis, Connect to this title online; UW restricted, 1998. http://hdl.handle.net/1773/10274.

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14

Rudd, M. Katharine. "Organization, evolution and function of alpha satellite DNA at human centromeres." Connect to text online, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=case1091493781.

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15

Beyer, Tracey Elaine, and Tracey Elaine Beyer. "Ontogeny of Unstable Chromosomes Formed by Telomere Replication Error." Diss., The University of Arizona, 2016. http://hdl.handle.net/10150/621103.

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The integrity of the genome relies on the maintenance of chromosomes, the structural embodiment of the genetic material. Disruption of chromosome replication can lead to extensive genomic rearrangements, spanning kilobase (Kb) to megabase (Mb) regions. Some chromosome rearrangements are inherently dynamic, beginning as a single unstable rearrangement from which multiple rearrangements emerge. The rare formation and transient behavior of unstable chromosomes renders their study challenging. Here I characterize the genetic ontogeny of unstable chromosomes in a budding yeast model, from initial r
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16

Walter, Joachim. "Dynamics of DNA repair factors and chromosomes studied by laser-UVA-microirradiation and laser photobleaching." Diss., [S.l.] : [s.n.], 2003. http://edoc.ub.uni-muenchen.de/archive/00001458/.

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17

Fernandes, Thiago. "Sequencias de DNA da estrutura cromossômica terminal de dípteros da família Sciaridae." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/41/41131/tde-10012013-150232/.

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A Ordem Diptera é constituída de milhares de espécies, cujo tempo de divergência pode chegar a 250 milhões de anos entre representantes das Sub-Ordens Brachycera e Nematocera. Esta janela temporal, no entanto, não é suficiente para explicar o aparecimento de estruturas cromossômicas terminais alternativas aos telômeros canônicos, conservados desde eucariontes unicelulares até mamíferos. Alguns autores admitem que estruturas não canônicas tenham sido geradas e selecionadas a partir de eventos mutacionais que resultaram na perda da telomerase em espécies ancestrais. Especulações deste tipo, embo
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18

Perrot, Anthony. "Understanding the establishment of the DNA replication program." Thesis, Rennes 1, 2016. http://www.theses.fr/2016REN1B052.

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La réplication de l’ADN est un processus essentiel qui doit avoir lieu une seule fois par cycle cellulaire. Ce processus hautement régulé et très conservé chez les eucaryotes, assure une complète duplication et donc une totale transmission de l’information génétique. Des changements dans le programme de réplication, qui est définit par le moment d’activation et la fréquence d’utilisation de l’ensemble des origines, ont été observés lors du développement, après induction de la différenciation chez des cellules souches embryonnaires de souris, ainsi que dans un grand nombre de cancers. La régula
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19

Alavattam, Kris G. "Epigenetic Regulation of the Sex Chromosomes and 3D Chromatin Organization in Male Germ Cells." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1563527048714711.

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20

Karcanias, Alexandra. "Investigation of genomic DNA copy number variation on the human sex chromosomes associated with genetic pathologies." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612017.

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21

Henning, Frederico. "Evolução de cromossomos sexuais em Eigenmannia virescens (Teleostei: Gymnotiformes)." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/41/41131/tde-05032008-163459/.

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Cromossomos sexuais evoluíram repetidas vezes independentemente nos grandes grupos de vertebrados. Sistemas sexuais altamente diferenciados e antigos são caracterizados por grandes diferenças morfológicas e de conteúdo gênico entre os dois cromossomos homólogos onde a recombinação é restrita a uma pequena região homóloga. Os sistemas recentes característicos de peixes caracterizam-se pela similaridade entre os cromossomos X e Y (ou Z e W), nos quais as diferenças observadas freqüentemente envolvem a presença de heterocromatina, translocações e inversões. A recombinação ocorre entre o par sexua
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22

Nascimento, Juliana 1982. "Isolamento, caracterização e localização cromossômica de sequências de DNA repetitivo de Physalaemus ephippifer (Anura Leiuperidae)." [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317684.

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Orientador: Luciana Bolsoni Lourenço Morandini<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-16T00:03:54Z (GMT). No. of bitstreams: 1 Nascimento_Juliana_M.pdf: 2159511 bytes, checksum: 592ca4a405512c2a06472a0c276eb206 (MD5) Previous issue date: 2010<br>Resumo: Os primeiros resultados citogenéticos obtidos para a espécie Physalaemus ephippifer, atualmente alocada no grupo P. cuvieri, mostraram um interessante heteromorfismo cromossômico ligado ao sexo. As 14 fêmeas analisadas presentaram um par cromossômico 8 heter
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23

Bardella, Vanessa Bellini [UNESP]. "Análise citogenética molecular em túbulos seminíferos de triatomíneos (Triatominae, Heteroptera)." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/92476.

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Made available in DSpace on 2014-06-11T19:26:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-02-26Bitstream added on 2014-06-13T19:12:50Z : No. of bitstreams: 1 bardella_vb_me_sjrp.pdf: 973541 bytes, checksum: 2642d082f6fe5ee2cb77ab3b60832684 (MD5)<br>Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)<br>Os heterópteros apresentam a meiose cística nos túbulos seminíferos. Esses possuem o cisto espermatogonial envolto pelas células císticas, as quais desenvolvem a função de nutrição das células em divisão celular. Quanto às características citogenéticas, esses in
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24

McGuigan, Amanda Jane. "Functional analysis of DNA cloned in yeast artificial chromosomes for replication and centromere function in mammalian cells." Thesis, Imperial College London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299885.

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25

Kong, Sim Yee. "Plasmid DNA and bacterial artificial chromosomes processing for gene therapy and vaccination : studies on membrane sterile filtration." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1444899/.

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Plasmids currently applied in clinical trials are generally < 20 kb, but the interest in larger circular vectors is rising. However, due to their size and character, filterability and irreversible damage intensified by elongational shear are major concerns during a sterilising filtration procedure. Therefore, key parameters affecting the normal-flow membrane filtration performance of solutions containing purified plasmid DNA and bacterial artificial chromosomes were investigated in this study. Two small scale filtration systems were designed to enable information on material properties to be o
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26

Garcia, Caroline. "Estudos cromossômicos e moleculares em Rhamdia (Pisces, Siluriformes, Heptapteridae): análise de relações evolutivas." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/41/41131/tde-29102009-163532/.

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O gênero Rhamdia, popularmente conhecido como jundiá, pertence à família Heptapteridae, uma das maiores radiações de bagres neotropicais de água doce. Estes peixes de médio porte e hábitos oportunistas e noturnos são encontrados em pequenos rios e córregos. No passado, Rhamdia foi considerado um dos gêneros mais especiosos dentro de Siluriformes, contando com cerca de 100 espécies descritas. Entretanto, após uma revisão taxonômica recente o número de espécies desse gênero foi reduzido a 12. Dados genéticos, de natureza cromossômica e molecular, caracterizam o gênero Rhamdia como um grupo que a
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27

SANTOS, Tiago Ribeiro Barros dos. "Os cromossomos holocêntricos de rhynchospora vahl (cyperaceae): Evolução cariotípica e diversidade de sequências satélites." Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/17678.

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Submitted by Irene Nascimento (irene.kessia@ufpe.br) on 2016-08-12T19:39:07Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Tese_versão_final_biblioteca_português.pdf: 2265965 bytes, checksum: 707851ccf48e28513fc34178bca7c739 (MD5)<br>Made available in DSpace on 2016-08-12T19:39:07Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Tese_versão_final_biblioteca_português.pdf: 2265965 bytes, checksum: 707851ccf48e28513fc34178bca7c739 (MD5) Previous issue date: 2016-03-04<br>Capes<br>Cromos
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28

Gimenez, Octavio Manuel Palacios [UNESP]. "Padrões de evolução de sistemas de cromossomos sexuais em grilos: uma abordagem integrada entre citogenética e genômica." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/152458.

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Submitted by OCTAVIO MANUEL PALACIOS GIMÉNEZ null (opalacios7@gmail.com) on 2018-01-10T10:10:20Z No. of bitstreams: 1 Tesis_completa.pdf: 26112515 bytes, checksum: 3ddefcdf63a47077ccb1b62c384cae1b (MD5)<br>Approved for entry into archive by Adriana Aparecida Puerta null (dripuerta@rc.unesp.br) on 2018-01-10T18:40:10Z (GMT) No. of bitstreams: 1 gimenez_omp_dr_rcla.pdf: 25788766 bytes, checksum: da0e0599de64bcf81bfb8ddceda0c8e7 (MD5)<br>Made available in DSpace on 2018-01-10T18:40:10Z (GMT). No. of bitstreams: 1 gimenez_omp_dr_rcla.pdf: 25788766 bytes, checksum: da0e0599de64bcf81bfb8ddceda0c
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Brind'Amour, Julie. "Flow cytometry analysis and sorting of chromosomes following hybridization with fluorescent probes that target specific DNA repeat sequences." Thesis, University of British Columbia, 2011. http://hdl.handle.net/2429/35973.

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Traditional cytogenetic approaches allow analysis of the chromosomal composition (karyotype) of mitotic cells fixed on slides cells by microscopy. The combination of karyotyping and Fluorescence In Situ Hybridization (FISH) enables the detection of specific target sequences on individual chromosomes. Disadvantages are that traditional cytogenetic approaches are very labor and time consuming and that chromosome specific information from only a few dozen cells has poor statistical power. An alternative is flow karyotyping, a method to analyze chromosomes in suspension by flow cytometry. For flow
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30

Mathrubutham, Umamaheshwar. "An investigation into the use of yeast artificial chromosomes for the identification of origins of replication in human DNA." Thesis, University of Southampton, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296259.

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31

Sandall, Sharsti L. "Dissecting centromeric DNA-microtubule interactions In vitro uncovers a mechanism that ensures proper connection of chromosomes to the mitotic spindle." Diss., [La Jolla, Calif.] : University of California, San Diego, 2008. http://wwwlib.umi.com/cr/ucsd/fullcit?p3325462.

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32

MacDonald, Anna Jayne, and n/a. "Sex chromosome microsatellite markers from an Australian marsupial: development, application and evolution." University of Canberra. n/a, 2008. http://erl.canberra.edu.au./public/adt-AUC20081217.122146.

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Microsatellites are simple repetitive DNA sequences that are used as genetic markers throughout the biological sciences. The high levels of variation observed at microsatellite loci contribute to their utility in studies at the population and individual levels. This variation is a consequence of mutations that change the length of microsatellite repeat tracts. Current understanding suggests that most mutations are caused by polymerase slippage during DNA replication and lead to changes of a single repeat unit in length, but some changes involving multiple repeats can also occur. Despite this s
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33

Oliveira, Vanessa Mancuso de. "Caracterização cariotipica de especies de Vermonia Schreb (Asteraceae: Vernonieae) com tecnicas de diferencial longitudinal de cromossomos (bandamentos e hibridação de DNA in situ)." [s.n.], 2008. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314935.

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Orientador: Eliana Regina Forni Martins<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-08-11T11:47:41Z (GMT). No. of bitstreams: 1 Oliveira_VanessaMancusode_M.pdf: 2101182 bytes, checksum: 4b6aba0f8011aa1dbf7656da7b98141b (MD5) Previous issue date: 2008<br>Resumo: O gênero Vernonia é o maior da tribo Vernonieae (Asteraceae), possuindo mais de 1.000 espécies. O Brasil é o maior centro de diversidade das espécies do Novo Mundo deste gênero. As subdivisões de Vernonia têm sido de difícil circunscrição devido ao seu tamanh
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34

Nord, Brita. "Endocrine tumour development : with special focus on chromosome arms 1p and 11q /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-166-7.

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35

Andrade, Alexandre de. "Identificação, caracterização e estudo da expressão dos genes hsc70 e hsp83 em Rhynchosciara americana." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-29122006-171314/.

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Com a idéia de identificar proteínas envolvidas no processo de enovelamento das proteínas sintetizadas na glândula salivar de Rhynchosciara americana, no início deste projeto adotou-se como estratégia o seqüenciamento de uma biblioteca de cDNA. Esta biblioteca foi construída utilizando-se glândulas salivares de Rhynchosciara americana do período de seu desenvolvimento onde tem início a síntese de seu casulo. Mensagens de proteínas envolvidas no processo de enovelamento, transporte e proteólise foram isoladas, alguns exemplos são hsc70, hsp83, hip, hop, dnaJ, trap1 e prolil isomerase, sec61&#94
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36

Delabaere, Laetitia. "Réplication, condensation et division des chromosomes parentaux dans le zygote de drosophile." Thesis, Lyon 1, 2014. http://www.theses.fr/2014LYO10280/document.

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Chez les animaux, la conformation unique du noyau du spermatozoïde dont la chromatine est organisée avec des protéines chromosomiques spécifiques telles que les protamines le rend totalement inactif. Le remodelage de la chromatine paternelle à la fécondation par des activités d'origine maternelle sont donc des processus essentiels à la formation d'un embryon diploïde, dont les mécanismes restent très mal connus. Lors de ma thèse j'ai essayé de mieux comprendre ces processus par l'étude, chez la drosophile, d'un mutant létal embryonnaire à effet maternel : maternal haploid (mh). Ce mutant affec
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37

Monfouilloux, Sylvaine. "Etude de la structure et de l'évolution d'une région de translocations sous télomériques chez l'homme." Rouen, 1997. http://www.theses.fr/1997ROUES065.

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Les extrémités des chromosomes comportent le télomère puis la région sous télomérique. Ces deux domaines se distinguent des autres régions chromosomiques car ils évoluent par des échanges entre les chromosomes hétérologues. Le télomère est une structure spécialisée constituant la fin des chromosomes et indispensable à leur stabilité. Il joue un rôle important dans l'organisation spatiale des chromosomes en particulier dans l'agglutination des extrémités chromosomiques en périphérie nucléaire. La région sous télomérique, adjacente au télomère est très redondante entre les chromosomes hétérologu
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38

Buchanan, Christina Diane. "Identification and characterization of a checkpoint triggered by delayed replication in S. cerevisiae /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/10253.

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Scacchetti, Priscilla Cardim. "Esttrutura cromossômica e caracterização cariotípica no gênero Characidium (Teleostei, Characiformes, Crenuchidae) /." Botucatu, 2015. http://hdl.handle.net/11449/139342.

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Orientador: Fauto Foresti<br>Coorientador: José Carlos Pansonato Alves<br>Banca: Diego Teruo Hashimoto<br>Banca: Marcelo Ricardo Vicari<br>Banca: Orlando Moreira Filho<br>Banca: Claudio de Oliveira<br>Resumo: No presente estudo, foram analisadas dezoito espécies de peixes do gênero Characidium, C. cf. zebra, C. tenue, C. xavante, C. stigmosum, Characidium sp1, Characidium sp2, Characidium sp3, Characidium sp4, Characidium sp5, Characidium sp6, C. pterostictum, C. vestigipinne, C. rachovii, C. orientale, C. serrano, C. timbuiense, C. vidali e Characidium sp. aff. C. vidali de diferentes bacias
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40

Cabuy, Erik. "Investigations of telomere maintenance in DNA damage response defective cells and telomerase in brain tumours." Thesis, Brunel University, 2005. http://bura.brunel.ac.uk/handle/2438/5157.

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Telomeres are nucleoprotein complexes located at the end of chromosomes. They have an essential role in protecting chromosome ends. Telomerase or ALT (alternative lengthening of telomeres) mechanisms maintain telomeres by compensating natural telomeric loss. We have set up a flow-FISH method and using mouse lymphoma cell lines we identified unexpectedly the presence of subpopulations of cells with different telomere lengths. Subpopulations of cells with different telomere lengths were also observed in a human ALT and non-ALT cell line. Differences in telomere length between subpopulations of c
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41

Stuckey, Samantha Anne. "Gene targeting at and distant from DNA breaks in yeast and human cells." Diss., Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/51721.

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Here we developed multiple genetic systems through which genetic modifications driven by DNA breaks caused by the I-SceI nuclease can be assayed in the yeast Saccharomyces cerevisiae and in human cells. Using the delitto perfetto approach for site-directed mutagenesis in yeast, we generated isogenic strains in which we could directly compare the recombination potential of different I-SceI variants. By genetic engineering procedures, we generated constructs in human cells for testing the recombination activity of the same I-SceI variants. Both in yeast and human cells we performed gene correcti
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42

Mendonça, Priscila Pasquetto [UNESP]. "Estudo comparativo das características citogenéticas e moleculares de Triatoma maculata e Triatoma pseudomaculata (Triatominae, Heteroptera)." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/92477.

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Made available in DSpace on 2014-06-11T19:26:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-02-19Bitstream added on 2014-06-13T20:33:40Z : No. of bitstreams: 1 mendonca_pp_me_sjrp.pdf: 681812 bytes, checksum: d7353da4e0742a18d8d505b0587fda7b (MD5)<br>Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)<br>Os triatomíneos são insetos hematófagos de grande importância para a parasitologia humana, pois são transmissores do Trypanosoma cruzi, protozoário causador da doença de Chagas. Além de sua importância médico-sanitária, os triatomíneos destacam-se pela sua citog
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43

Oliveira, Ezequiel Aguiar de. "Evolução cromossômica em peixes da família Erythrinidae (Characiformes). Citogenética comparativa entre espécies do gênero Hoplias." Universidade Federal de São Carlos, 2015. https://repositorio.ufscar.br/handle/ufscar/8719.

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Submitted by Aelson Maciera (aelsoncm@terra.com.br) on 2017-05-02T18:22:22Z No. of bitstreams: 1 DissEAO.pdf: 2220035 bytes, checksum: b18c61d42ff58647fa114291931a35ab (MD5)<br>Approved for entry into archive by Ronildo Prado (ronisp@ufscar.br) on 2017-05-04T13:29:04Z (GMT) No. of bitstreams: 1 DissEAO.pdf: 2220035 bytes, checksum: b18c61d42ff58647fa114291931a35ab (MD5)<br>Approved for entry into archive by Ronildo Prado (ronisp@ufscar.br) on 2017-05-04T13:29:11Z (GMT) No. of bitstreams: 1 DissEAO.pdf: 2220035 bytes, checksum: b18c61d42ff58647fa114291931a35ab (MD5)<br>Made available in DSp
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44

Bardella, Vanessa Bellini. "Análise citogenética molecular em túbulos seminíferos de triatomíneos (Triatominae, Heteroptera) /." São José do Rio Preto : [s.n.], 2010. http://hdl.handle.net/11449/92476.

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Orientador: Maria Tercília Vilela de Azeredo Oliveira<br>Banca: Hermione Elly Melara de Campos Bicudo<br>Banca: Patricia Pasquali Parise Maltempi<br>Resumo: Os heterópteros apresentam a meiose cística nos túbulos seminíferos. Esses possuem o cisto espermatogonial envolto pelas células císticas, as quais desenvolvem a função de nutrição das células em divisão celular. Quanto às características citogenéticas, esses insetos apresentam cromossomos holocinéticos, baixa variabilidade cariotípica e meiose invertida dos cromossomos sexuais. No presente trabalho foram caracterizadas as células císticas
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45

Scacchetti, Priscilla Cardim [UNESP]. "Esttrutura cromossômica e caracterização cariotípica no gênero Characidium (Teleostei, Characiformes, Crenuchidae)." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/139342.

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Made available in DSpace on 2016-06-07T17:12:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-02-27. Added 1 bitstream(s) on 2016-06-07T17:16:47Z : No. of bitstreams: 1 000864281.pdf: 2841286 bytes, checksum: e1b59c63f77c2d49bd85b14c3d63dde2 (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>No presente estudo, foram analisadas dezoito espécies de peixes do gênero Characidium, C. cf. zebra, C. tenue, C. xavante, C. stigmosum, Characidium sp1, Characidium sp2, Characidium sp3, Characidium sp4, Characidium sp5, Characidium sp6, C. pterostictum, C. vestigipinne,
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Terry, Samantha Y. A. "A role for topoisomerase II alpha in chromosome damage in human cell lines." Thesis, University of St Andrews, 2010. http://hdl.handle.net/10023/873.

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Human response to ionising radiation (IR) shows a wide variation. This is most clearly seen in the radiation-response of cells as measured by frequencies of chromosomal aberrations. Different frequencies of IR-induced aberrations can be conveniently observed in phytohaemagglutin-stimulated peripheral blood T-lymphocytes from both normal individuals and sporadic cancer cases, in either metaphase chromosomes or as micronuclei in the following cell cycle. Metaphase cells show frequent chromatid breaks, defined as chromatid discontinuities or terminal deletions, if irradiated in the G 2 -phase of
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47

Griese, Julia Johanna. "Structures and DNA-Binding Activities of the Hinge Domains from the Structural Maintenance of Chromosomes Proteins of Pyrococcus furiosus and the Mouse Condensin Complex." Diss., lmu, 2010. http://nbn-resolving.de/urn:nbn:de:bvb:19-122003.

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Oliveira, Thays Duarte de. "Organização genômica de sequências repetitivas em Pica-paus (aves piciformes)." Universidade Federal do Pampa, 2017. http://dspace.unipampa.edu.br:8080/xmlui/handle/riu/1544.

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49

Saini, Natalie. "Understanding the mechanisms underlying DSB repair-induced mutagenesis at distant loci in yeast." Diss., Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/51843.

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Increased mutagenesis is a hallmark of cancers. On the other hand, this can trigger the generation of polymorphisms and lead to evolution. Lately, it has become clear that one of the major sources of increased mutation rates in the genome is chromosomal break formation and repair. A variety of factors can contribute to the generation of breaks in the genome. A paradoxical source of breaks is the sequence composition of the genomic DNA itself. Eukaryotic and prokaryotic genomes contain sequence motifs capable of adopting secondary structures often found to be potent inducers of double str
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Päsold, Susanne. "Entwicklung eines FISH-Referenzkaryotyps der Zuckerrübe (Beta vulgaris) für die Integration genetischer Kopplungskarten und die Analyse der chromosomalen Verteilung von repetitiven Sequenzen." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-131410.

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Die Verbindung von genetischen, physikalischen und zytologischen Daten ist entscheidend für die Genom- und Chromosomenanalyse. Obwohl Beta vulgaris (2n = 18) als wichtige Kulturpflanze und Untersuchungsobjekt der Grundlagenforschung eine intensiv analysierte Art darstellt, existiert bisher keine Verknüpfung zwischen Kopplungsgruppen (LG) und Chromosomen. B.-vulgaris-Chromosomen können zudem aufgrund fehlender morphologischer Unterscheidungsmerkmale bisher nicht einzeln identifiziert und klassifiziert werden. Somit sind zytogenetisch gewonnene Ergebnisse nicht ohne weiteres auf genetische Koppl
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