Relevant bibliographies by topics / DNA hydrolysis

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'DNA hydrolysis'

Author: Grafiati
Published: 4 June 2021
Last updated: 26 July 2025

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Journal articles on the topic "DNA hydrolysis"

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Fekry, Mostafa I., and Kent S. Gates. "DNA-catalyzed hydrolysis of DNA phosphodiesters." Nature Chemical Biology 5, no. 10 (2009): 710–11. http://dx.doi.org/10.1038/nchembio.224.

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Zhou, Cong, Joshua L. Avins, Paul C. Klauser, Benjamin M. Brandsen, Yujeong Lee, and Scott K. Silverman. "DNA-Catalyzed Amide Hydrolysis." Journal of the American Chemical Society 138, no. 7 (2016): 2106–9. http://dx.doi.org/10.1021/jacs.5b12647.

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Franklin, Sonya J. "Lanthanide-mediated DNA hydrolysis." Current Opinion in Chemical Biology 5, no. 2 (2001): 201–8. http://dx.doi.org/10.1016/s1367-5931(00)00191-5.

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Chandra, Madhavaiah, Amit Sachdeva, and Scott K. Silverman. "DNA-catalyzed sequence-specific hydrolysis of DNA." Nature Chemical Biology 5, no. 10 (2009): 718–20. http://dx.doi.org/10.1038/nchembio.201.

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Unciuleac, Mihaela-Carmen, Aviv Meir, Chaoyou Xue, Garrett M. Warren, Eric C. Greene, and Stewart Shuman. "Clutch mechanism of chemomechanical coupling in a DNA resecting motor nuclease." Proceedings of the National Academy of Sciences 118, no. 11 (2021): e2023955118. http://dx.doi.org/10.1073/pnas.2023955118.

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Mycobacterial AdnAB is a heterodimeric helicase–nuclease that initiates homologous recombination by resecting DNA double-strand breaks (DSBs). The N-terminal motor domain of the AdnB subunit hydrolyzes ATP to drive rapid and processive 3′ to 5′ translocation of AdnAB on the tracking DNA strand. ATP hydrolysis is mechanically productive when oscillating protein domain motions synchronized with the ATPase cycle propel the DNA tracking strand forward by a single-nucleotide step, in what is thought to entail a pawl-and-ratchet–like fashion. By gauging the effects of alanine mutations of the 16 ami
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Singh, Reema, Sumudu R. Perera, George S. Katselis та ін. "A β-lactamase-producing plasmid from Neisseria gonorrhoeae carrying a unique 6 bp deletion in blaTEM-1 encoding a truncated 24 kDa TEM-1 penicillinase that hydrolyses ampicillin slowly". Journal of Antimicrobial Chemotherapy 74, № 10 (2019): 2904–12. http://dx.doi.org/10.1093/jac/dkz306.

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AbstractBackgroundSeven structurally related β-lactamase-producing plasmids have been characterized in penicillinase-producing Neisseria gonorrhoeae (PPNG) isolates. We characterized a variant (i.e. pJRD20, Canada type) of the Africa-type (pJD5) plasmid isolated from N. gonorrhoeae strain 8903.ObjectivesTo compare the DNA sequence of pJRD20 with that of pJD5 and pJD4 (Asia-type) and their TEM-1 β-lactamases.MethodsN. gonorrhoeae 8903 was identified as part of the Gonococcal Antimicrobial Surveillance Program in Canada. β-Lactamase production was assessed using nitrocefin. MICs were determined
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Zilhadia, Zilhadia, Afifah Nurul Izzah, and Ofa Suzanti Betha. "Perbandingan Metode SYBR Green dan Hydrolysis Probe dalam Analisis DNA Gelatin Sapi dan Gelatin Babi Menggunakan Real Time Polymerase Chain Reaction." Jurnal Sains Farmasi & Klinis 4, no. 1 (2017): 16. http://dx.doi.org/10.29208/jsfk.2017.4.1.194.

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Pemanfaatan gelatin secara luas menimbulkan kontroversi dan kekhawatiran bagi masyarakat muslim karena pada umumnya gelatin terbuat dari kulit babi dan sapi. Salah satu teknik analisis yang dapat membedakan gelatin sapi dan gelatin babi adalah Real Time Polymerase Chain Reaction (PCR). Real Time PCR merupakan metode analisis berbasis DNA yang handal, efektif, dan terpecaya. Dalam analisis kualitatif dan kuantitatif, Real Time PCR membutuhkan pewarna fluoresens. Pewarna fluoresens yang umum digunakan adalah SYBR green dan hydrolysis probe. Telah dilakukan perbandingan antara metode SYBR green d
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Jackson, A. P., and A. Maxwell. "Identifying the catalytic residue of the ATPase reaction of DNA gyrase." Proceedings of the National Academy of Sciences 90, no. 23 (1993): 11232–36. http://dx.doi.org/10.1073/pnas.90.23.11232.

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We propose a mechanism for the hydrolysis of ATP by the DNA gyrase B protein in which Glu42 acts as a general base and His38 has a role in aligning and polarizing the glutamate residue. We have tested this mechanism by site-directed mutagenesis, converting Glu42 to Ala, Asp, and Gln, and His38 to Ala. In the presence of wild-type A protein, B proteins bearing the mutations Ala42 and Gln42 show no detectable supercoiling or ATPase activities, while Asp42 and Ala38 proteins have reduced activities. In the DNA cleavage and relaxation reactions of gyrase, which do not require ATP hydrolysis, wild-
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Koehler, D. R., and P. C. Hanawalt. "Digestion of damaged DNA by the T7 DNA polymerase-exonuclease." Biochemical Journal 293, no. 2 (1993): 451–53. http://dx.doi.org/10.1042/bj2930451.

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We have investigated the 3′-5′-exonuclease activity of phage T7 DNA polymerase for its usefulness as an approach for the detection of lesions in DNA. Unlike the T4 DNA polymerase-exonuclease, which is commonly used to map the position and frequency of lesions in very small DNA fragments, T7 DNA polymerase-exonuclease is able to hydrolyse almost completely the large fragments from KpnI-restricted mammalian DNA. However, we found that the exonuclease was also able to hydrolyse DNA containing several kinds of lesions: cyclobutane pyrimidine dimers, thymine glycols, and mono-adducts of 4′-hydroxym
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Ott, R., and R. Krämer. "DNA hydrolysis by inorganic catalysts." Applied Microbiology and Biotechnology 52, no. 6 (1999): 761–67. http://dx.doi.org/10.1007/s002530051588.

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Dissertations / Theses on the topic "DNA hydrolysis"

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Evans, Steven John. "Structure, function and mechanism of action of bovine pancreatic deoxyribonuclease I : role of amino acid residues involved in phosphate contacts." Thesis, University of Newcastle Upon Tyne, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321857.

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Przybylski, Jennifer L., and University of Lethbridge Faculty of Arts and Science. "Computational modeling of the hydrolysis of 2'-deoxyribonucleic acids." Thesis, Lethbridge, Alta. : University of Lethbridge, Dept. of Chemistry and Biochemistry, c2009, 2009. http://hdl.handle.net/10133/1292.

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The mechanism for the hydrolysis of 2′-deoxyribonucleosides is examined using computational chemistry techniques. Initially, a model capable of accurately predicting the mechanism and activation barrier for the uncatalyzed hydrolysis of 2′-deoxyuridine is designed. It is found that the smallest model includes both explicit and implicit solvation during the optimization step. Next, this hybrid solvation model is applied to four natural nucleosides, namely 2′-deoxyadenosine, 2′-deoxycytidine, 2′-deoxyguanosine and thymidine. The hybrid model correctly predicts the trend in activation Gibbs energ
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Eissa, Omaima Abdel-Latif Elkotb. "Cloning of a novel operon containing genes for 4-#alpha#-glucanotransferase, maltodextrin phosphorylase, and a regulatory protein from Clostridium butyricum." Thesis, University of Southampton, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296246.

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Marrone, April. "THE BIOCHEMICAL REACTIONS OF DRY STATE DNA." Doctoral diss., University of Central Florida, 2009. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3622.

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The biochemistry of dry state DNA is of interest to the fields of forensics, ancient DNA, and DNA storage. The exact chemical nature of the degradation of the DNA molecule in the dry state has not been studied prior. If determined what chemical changes the DNA molecule undergoes, to what degree and in what time frame then protocols can be implemented to bypass the impact of this damage or to repair it when necessary. It is suspected that similar reactions occur to the dry state DNA molecule as does to the hydrated molecule. It cannot be assumed, however that these types of chemical processes o
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Bhat, Anayat [Verfasser]. "Live Cell Fluorescence Imaging of Nucleotide Dynamics : ATP Hydrolysis and DNA Damage Response / Anayat Bhat." Konstanz : KOPS Universität Konstanz, 2021. http://d-nb.info/1229351094/34.

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Marin, Córdoba Roberto. "Chromium carcinogenesis characterization of DNA damaging intermediates by EPR ³¹P NMR, HPLC, ESI-MS and magnetic susceptibility /." Ohio : Ohio University, 2010. http://www.ohiolink.edu/etd/view.cgi?ohiou1261417590.

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Moysan-Le, Meur Annie. "Caracterisation de dosage des produits de photoaddition de psoralene dans l'adn "in vitro" et dans l'adn cellulaire." Paris 6, 1987. http://www.theses.fr/1987PA066021.

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Marin, Cordoba Roberto. "Chromium Carcinogenesis: Characterization of DNA damaging Intermediates by EPR 31P NMR, HPLC, ESI-MS and Magnetic Susceptibility." Ohio University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1261417590.

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Taori, Vijay P. "Poly(glycoamidoamine)s: Understanding their Structure and Structure-Bioactivity Relationships." Diss., Virginia Tech, 2010. http://hdl.handle.net/10919/77982.

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In order to achieve efficient therapeutic effect, it is important to understand the structure of biomaterials that are used in the therapeutic delivery system. This dissertation is dedicated towards understanding the hydrolysis pattern of plasmid DNA (pDNA) delivery vehicles comprised of poly(glycoamidoamine)s (PGAAs) under physiological conditions and effects of subtle changes in the chemical structure of the PGAAs on its biological performance. The unusual hydrolysis of the tartarate and galactarate based PGAAs was investigated by studying the hydrolysis of small model molecules which mimic
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Incardona, Marie-Françoise. "Mesure de lésions de type oxydatif de l'ADN dans les fluides biologiques et dans l'ADN isolé." Grenoble 1, 1994. http://www.theses.fr/1994GRE10162.

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Divers facteurs (stress oxydant, exposition a divers rayonnements) peuvent engendrer des modifications des bases de l'adn. La mise au point de methodes d'analyse suffisamment fiables et sensibles nous a permis de detecter et de doser plusieurs dommages oxydatifs dans un fluide biologique (urine humaine) et dans l'adn isole. Pour cela, deux techniques ont ete respectivement mises en uvre: la chromatographie gazeuse couplee a la spectrometrie de masse (cg/sm) et la chromatographie liquide a haute performance associee a une detection electrochimique (clhp/ec). La mise au point de methodes de dete
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Books on the topic "DNA hydrolysis"

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Mannermaa, Riitta-Maaria. Sequence-specific DNA binding of histone H1: Differential effect of nucleotides and evidence for nucleoside triphosphate hydrolysis by histone H1. University of Oulu], Collagen Research Unit, Biocenter and Department of Medical Biochemistry, 1992.

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Estes, Patricia S. Cardiovascular and respiratory responses of the ghost shrimp, Callianassa californiensis Dana, to the pesticide carbaryl and its hydrolytic product 1-naphthol. 1986.

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Book chapters on the topic "DNA hydrolysis"

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Williams, N. H. "DNA Hydrolysis: Mechanism and Reactivity." In Artificial Nucleases. Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-642-18510-6_2.

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Testillano, P. S., M. C. Risueño, M. A. Ollacarizqueta, and C. J. Tandler. "Selective Staining of DNA at the Ultrastructural Level After Alkaline Hydrolysis." In Nuclear Structure and Function. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4613-0667-2_98.

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Komiyama, Makoto, Naoya Takeda, and Makoto Irisawa. "Synergism of Two Metal Ions for the Hydrolysis of DNA and RNA." In DNA and RNA Cleavers and Chemotherapy of Cancer and Viral Diseases. Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-009-0251-0_22.

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Guengerich, F. Peter. "Hydrolytic, Deamination, and Rearrangement Reactions of DNA Adducts." In Molecular Life Sciences. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-6436-5_376-1.

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Guengerich, Frederick Peter. "Hydrolytic, Deamination, and Rearrangement Reactions of DNA Adducts." In Molecular Life Sciences. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4614-1531-2_376.

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Orebaugh, Clinton D., Scott A. Lujan, Adam B. Burkholder, Anders R. Clausen, and Thomas A. Kunkel. "Mapping Ribonucleotides Incorporated into DNA by Hydrolytic End-Sequencing." In Methods in Molecular Biology. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7306-4_23.

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Travers, Andrew. "Mapping histone positions in chromatin by protein-directed DNA crosslinking and cleavage." In DNA-Protein Interactions. Oxford University PressOxford, 2000. http://dx.doi.org/10.1093/oso/9780199636921.003.0017.

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Abstract 1 Introduction The precise mapping of protein-binding sites on DNA can be facilitated by the covalent conjugation of an activatable reagent to a specific amino acid residue on the protein of interest. ln this procedure, the conjugated protein is first bound lo DNA and then the reagent is activated. Two general methods are currently used. The activated reagent can crosslink to DNA in van der Waals’ contact <1nd thus sensitize the backbone to alkaline hydrolysis in the immediate vicinity of the crosslink.
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Lindsley, Janet E. "Type II DNA topoisomerases: Coupling directional DNA transport to ATP hydrolysis." In Energy Coupling and Molecular Motors. Elsevier, 2003. http://dx.doi.org/10.1016/s1874-6047(04)80009-x.

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Beaton, Graham, Douglas Dellinger, William S. Marshall, and Marvin H. Caruthers. "Synthesis of Oligonucleotide Phosphorodithioates." In Oligonucleotides and Analogues. Oxford University PressOxford, 1991. http://dx.doi.org/10.1093/oso/9780199632800.003.0005.

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Abstract Over the past several years, the development of high yielding, rapid methods for synthesizing DNA (1-3) have led to a large number of applications for oligonucleotides (4). These include its use for cloning and synthesizing genes (5), as primers for sequencing DNA and various PCR applications (6), mutagenesis of genes in a site-specific manner (7), examination of how nucleic acids interact with proteins (8), and for studies on nucleic acid structure (9). Mainly because of these results, many have discovered that synthetic DNA needs to be further modified so that it resists hydrolysis
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Naegeli, Hanspeter. "Enzyinology of huinan nucleotide excision repair." In DNA Recombination and Repair. Oxford University PressOxford, 1999. http://dx.doi.org/10.1093/oso/9780199637072.003.0005.

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Abstract Damaged bases are eliminated from human genomes by two completely different excision mechanisms: repair by base excision and repair by nucleotide excision. Base excision involves the hydrolysis of N-glycosidic bonds and is restricted to a rather narrow range of defective or inappropriate DNA constituents (1, 2). Nucleotide excision repair (NER), on the other hand, proceeds through dual endonucleolytic cleavage of damaged strands and is capable of removing a nearly infinite variety of base lesions with little regard for the modification itself. The extraordinary substrate versatility o
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Conference papers on the topic "DNA hydrolysis"

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GANDELMAN, O., LC TISI, PJ WHITE, JAH MURRAY, and DJ SQUIRRELL. "BIOLUMINESCENT DETECTION OF RNA HYDROLYSIS PROBES IN DNA TESTING." In Proceedings of the 13th International Symposium. WORLD SCIENTIFIC, 2005. http://dx.doi.org/10.1142/9789812702203_0126.

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Kurita, Hirofumi, Ken-ichi Inaishi, Ken Torii, et al. "Real-time direct observation of single-molecule DNA hydrolysis by exonucleaseIII." In 2006 IEEE International Symposium on Micro-NanoMechatronics and Human Science. IEEE, 2006. http://dx.doi.org/10.1109/mhs.2006.320277.

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Kurita, Hirofumi, Ken Torii, Hachiro Yasuda, Kazunori Takashima, Shinji Katsura, and Akira Mizuno. "Single-molecule Observation of DNA Hydrolysis by ExonucleaseIII; Effect of Physical Form of DNA on Exonuclease Reaction." In 2007 International Symposium on Micro-NanoMechatronics and Human Science. IEEE, 2007. http://dx.doi.org/10.1109/mhs.2007.4420842.

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Nikitin, A. O., A. M. Timofeeva, S. E. Sedykh, and G. A. Nevinsky. "ANTIBODY ACTIVITY IN MICRORNA HYDROLYSIS: ROLE IN GENE REGULATION IN VIRAL INFECTIONS." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-351.

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Antibodies with catalytic activity, hydrolyzing DNA, RNA and some oligopeptides have been described in a number of viral and autoimmune diseases. Antibodies with RNA-hydrolyzing activity can be important in the degradation of microRNAs and, as a consequence, in the change in the regulation of genes carried out with the help of microRNAs. The aim of this work is to investigate the activity of antibodies of HIV-infected patients in microRNA hydrolysis.
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Krasnoshtanova, Alla, and Elisaveta Borovkova. "OBTAINING NUCLEIC ACID PREPARATIONS AND THEIR HYDROLYSATES FROM BIOMASS OF METHANE-OXIDIZING BACTERIA." In GEOLINKS Conference Proceedings. Saima Consult Ltd, 2021. http://dx.doi.org/10.32008/geolinks2021/b1/v3/14.

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"Due to the unfavourable environmental, social and economic situation, the need for the treatment of oncological diseases and diseases associated with impaired activity of the immune system is increasing. A lot of these drugs are made on the basis of nucleic acid components, the industrial production of which is practically non-existent in Russia. Therefore, a task of current interest is to develop the basis of the technology for obtaining components of nucleic acids, which can be widely used in medicine as immunomodulatory, wound-healing, antiviral, and diagnostic medicine, as well as for can
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Liao, Jung-Chi, and George Oster. "The Engines of Biomolecular Motors." In ASME 2004 3rd Integrated Nanosystems Conference. ASMEDC, 2004. http://dx.doi.org/10.1115/nano2004-46094.

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The majority of biomolecular motors are powered by nucleoside triphosphate (NTP), especially adenosine triphosphate (ATP). These motors consist of a β-sheet with highly conserved motifs and the nucleotide binding domain around it. The highly conserved protein folds are the engines of these motors, which convert the energy of NTP hydrolysis cycle to mechanical work. Although functions of molecular motors are widely diverse, (including cargo movement, DNA unwinding, protein degradation, ion pumping, etc), the nucleotide binding domains are very similar. In the binding site, NTP undergoes a hydro
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Matić, Sanja, Snežana Stanić, Nevena Tomašević, Rino Ragno, and Milan Mladenović. "DISCLOSING THE TRUE NATURE OF HESPERETIN’S ANTIGENOTOXICITY „IN VIVO“ WITHIN THE „DROSOPHILA MELANOGASTER“ SOMATIC CELLS THROUGH THE EXTENSIVE GENOTOXICAL AND STRUCTURE-BASED STUDIES." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.427m.

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Previously unreported genotoxic and antigenotoxic potentials of hesperetin (Hes) were revealed by treating the Drosophila melanogaster (dm) whose DNA has been altered by means of O6-ethylguanine (dmGO6-Et) and O4-ethylthymine (dmTO4-Et) lesions appearance, caused by ethyl methanesulfonate (EMS), a proven alkylating agent and mutagen. Therefore, Hes potencies were determined by means of the comet assay on somatic cells level, where compound exerted no genotoxic effects but acted genotoxically as a Topoisomerase IIα (dmTopIIα) catalytic inhibitor by invading the Binding and Cleavage Domain and s
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Homes, W. E., H. R. Lijnen, L. Nelles, C. Kluft та D. Collen. "AN ALANINE INSERTION IN α2-ANTIPLASMIN ‘ENSCHEDE’ ABOLISHES ITS PLASM IN INHIBITORY ACTIVITY". У XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642897.

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Congenital deficiencies of the fibrinolytic inhibitor α2antiplasmin (α2AP) may result in bleeding disorders. An abnormal a AP (α2AP‘Enschede’) is known. 2 siblings with 3% functional activity and normal antigen level have parents with 50% activity and normal antigen. The protein interacts normally with the lysine-binding site(s) of plasmin(ogen) but does not inhibit plasmin irreversibly. α2AP Enschede is a plasmin substrate that like the normal protein releases a M 8,000 peptide upon reaction with plasmin. In the present study, Southern blot analysis, using an α2AP cDNA probe showed a restrict
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Maria Ferreira Jardim Da Silveira, Jose, and Pedro Lucas Chagas MendonÇa. "Patents Trajectories Analysis: Enzymatic Hydrolysis and Bioethanol." In XXIII Congresso de Iniciação Científica da Unicamp. Galoá, 2015. http://dx.doi.org/10.19146/pibic-2015-37737.

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Lucas Chagas MendonÇa, Pedro, and Jose Maria Ferreira Jardim Da Silveira. "Patents Trajectories Analysis: Enzymatic Hydrolysis and Bioethanol." In XXIV Congresso de Iniciação Científica da UNICAMP - 2016. Galoa, 2016. http://dx.doi.org/10.19146/pibic-2016-50630.

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Reports on the topic "DNA hydrolysis"

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Sooksai, Sarintip, Nanthika Khongchareonporn, Aphichart Karnchanatat, Shongchan Phuthong, Sajee Noitang, and Sawanan Thongyoo. Enhancement of recombinant monomeric insulin production in methylotrophic yeasts by increasing copy number of gene : Completed research report (2nd year). Chulalongkorn University, 2016. https://doi.org/10.58837/chula.res.2016.59.

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Insulin is a hormone that is produced in pancreas. It is important for regulation of blood sugar level. The active form of insulin is monomer which contains 51 amino acids in two peptide chains. Currently, improvement of insulin production was done by using recombinant DNA technology in bacteria and yeasts. The obtained recombinant insulin is easier to be purified than the pancreatic insulin. This research has been using the recombinant yeast, Pichia pastoris KM71H (TP1), which has a cassette of monomeric insulin precursor (MIP) to produce recombinant MIP. The recombinant MIP was induced to be
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Lers, Amnon, E. Lomaniec, S. Burd, A. Khalchitski, L. Canetti, and Pamela J. Green. Analysis of Senescence Inducible Ribonuclease in Tomato: Gene Regulation and Function. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7570563.bard.

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Natural leaf senescence has a negative influence on yield. Postharvest induced senescence contributes to the losses of quality in flowers, foliage, and vegetables. Strategies designed to control the senescence process in crop plants could therefore have great applied significance. Senescence is regulated by differential gene expression yet, functional characterization of the genes specifically induced and study of their expression control, is still in its infancy. Study of senescence-specific genes is required to allow identification of regulatory elements participating in senescence-induced e
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