Academic literature on the topic 'DNA selectivity'

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Journal articles on the topic "DNA selectivity"

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Reiss, Carol Shoshkes. "Selectivity and Quality." DNA and Cell Biology 32, no. 3 (2013): 89. http://dx.doi.org/10.1089/dna.2013.2526.

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Oberemok, V., and P. Nyadar. "The selectivity of DNA insecticides." Archives of Biological Sciences 66, no. 4 (2014): 1479–83. http://dx.doi.org/10.2298/abs1404479o.

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Langenegger, Simon M., and Robert Häner. "Selectivity in DNA interstrand-stacking." Bioorganic & Medicinal Chemistry Letters 16, no. 19 (2006): 5062–65. http://dx.doi.org/10.1016/j.bmcl.2006.07.039.

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Warpehoski, Martha A., and Laurence H. Hurley. "Sequence selectivity of DNA covalent modification." Chemical Research in Toxicology 1, no. 6 (1988): 315–33. http://dx.doi.org/10.1021/tx00006a001.

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Iqbal, Samir M., Demir Akin, and Rashid Bashir. "Solid-state nanopore channels with DNA selectivity." Nature Nanotechnology 2, no. 4 (2007): 243–48. http://dx.doi.org/10.1038/nnano.2007.78.

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Garg, A., and J. Bell. "Reexamining the DNA target selectivity of Scalloped." Genome 53, no. 8 (2010): 575–84. http://dx.doi.org/10.1139/g10-029.

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Selector proteins are transcription factors that coordinate the formation and identity of organs and appendages. The proper formation of these tissues requires the selector proteins to regulate the expression of a large set of genes. Many selector proteins are involved in regulating multiple developmental processes, yet it is not completely clear how they are able to activate different sets of genes in a tissue-specific manner. An association with cofactors is thought to be one method by which enhancer selectivity is achieved. During wing development the selector protein Scalloped (SD) interac
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Thomas, Thresia, and T. J. Thomas. "Selectivity of polyamines in triplex DNA stabilization." Biochemistry 32, no. 50 (1993): 14068–74. http://dx.doi.org/10.1021/bi00213a041.

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Huang, Haidong, and Peter C. Tlatelpa. "Tuning the selectivity of triplex DNA receptors." Chemical Communications 51, no. 25 (2015): 5337–39. http://dx.doi.org/10.1039/c4cc07805e.

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Leichnitz, S., J. Heinrich, and N. Kulak. "A fluorescence assay for the detection of hydrogen peroxide and hydroxyl radicals generated by metallonucleases." Chemical Communications 54, no. 95 (2018): 13411–14. http://dx.doi.org/10.1039/c8cc06996d.

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ROS quench assays for metal-based DNA cleavage show low selectivity and reliability – a fluorogenic assay was thus developed to reliably, selectively and sensitively detect H<sub>2</sub>O<sub>2</sub> and HO˙.
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Park, Ki Soo, Chang Yeol Lee, and Hyun Gyu Park. "Target DNA induced switches of DNA polymerase activity." Chemical Communications 51, no. 49 (2015): 9942–45. http://dx.doi.org/10.1039/c5cc02060c.

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A novel concept that target DNA can induce switching of DNA polymerase activity is devised. The method relies on the finding that a DNA aptamer can undergo conformational change upon hybridization with a complementary target DNA, which leads to activation or inactivation of DNA polymerase. This strategy is utilized to identify the presence of target DNA with high levels of sensitivity and selectivity.
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Dissertations / Theses on the topic "DNA selectivity"

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Hayes, Amy M. "Sequence Selectivity and Cytotoxicity of a Series of Azinomycin “Top-Half” Partial Structures." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1218639687.

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Woodward, Robert L. "Azinomycin A and B epoxyamide stereochemistry relevance to DNA sequence selectivity /." Connect to resource, 2006. http://hdl.handle.net/1811/6528.

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Thesis (Honors)--Ohio State University, 2006.<br>Title from first page of PDF file. Document formatted into pages: contains xi, 29 p.; also includes graphics. Includes bibliographical references (p. 27-29). Available online via Ohio State University's Knowledge Bank.
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Wong-Deyrup, Siu Wah. "DNA sequence selectivity and kinetic properties of de novo designed metalloprotein dimers." Diss., University of Iowa, 2007. http://ir.uiowa.edu/etd/185.

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Pickup, Michael Brennan. "New methodology in the determination of sequence-selectivity in small molecule-DNA binding." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286346.

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Yan, Wei. "Design of artificial 6-zinc finger peptides : linker alteration and DNA binding selectivity." 京都大学 (Kyoto University), 2008. http://hdl.handle.net/2433/137164.

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Boccongelli, Marina. "Etude expérimentale de la stabilité, sélectivité d'appariement et dynamique d'oligonucléotides DNA-DNA et LNA-DNA." Doctoral thesis, Universite Libre de Bruxelles, 2008. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210549.

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Le traitement et le diagnostic de maladies d'origine génétique suscite un grand intérêt à l'heure actuelle. De par leur spécificité d'appariement avec les acides nucléiques, les oligonucléotides possèdent un grand potentiel dans ce domaine. Ils se heurtent toutefois à des limitations majeures, dont leur faible stabilité en milieu physiologique et la difficulté qu'ils ont à franchir les membranes biologiques. De nombreuses équipes de recherche s'intéressent, afin de pallier ces limitations, à la conception et à la synthèse d'oligonucléotides chimiquement modifiés. Parmi ceux-ci, les Locked Nucl
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Rathi, Preeti [Verfasser], Daniel [Akademischer Betreuer] Summerer, and Leif [Gutachter] Dehmelt. "Isolation of genomic DNA sequences with expanded nucleobase selectivity using Transcription Activator-Like Effector Proteins / Preeti Rathi ; Gutachter: Leif Dehmelt ; Betreuer: Daniel Summerer." Dortmund : Universitätsbibliothek Dortmund, 2017. http://d-nb.info/1160443246/34.

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Kurtovic, Sanela. "Directed Evolution of Glutathione Transferases Guided by Multivariate Data Analysis." Doctoral thesis, Uppsala University, Department of Biochemistry and Organic Chemistry, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8718.

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<p>Evolution of enzymes with novel functional properties has gained much attention in recent years. Naturally evolved enzymes are adapted to work in living cells under physiological conditions, circumstances that are not always available for industrial processes calling for novel and better catalysts. Furthermore, altering enzyme function also affords insight into how enzymes work and how natural evolution operates. </p><p>Previous investigations have explored catalytic properties in the directed evolution of mutant libraries with high sequence variation. Before this study was initiated, funct
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Sunderland, Peter T. "Design and synthesis of selective inhibitors of poly(ADP-ribose)polymerase-2." Thesis, University of Bath, 2010. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.528371.

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Musetti, Caterina Livia. "Heterocyclic Cations as Potential Anticancer Agents: An Approach that Targets G-quadruplex with Different Binding Modes." Digital Archive @ GSU, 2010. http://digitalarchive.gsu.edu/chemistry_theses/26.

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G-quadruplex structures are found in important regions of the eukaryotic genome, such as telomeres and regulatory sequences of genes, and are likely to play important roles in regulation of biological events. The significant structural differences with duplex DNA make quadruplex DNA a very attractive target for anticancer drug design. The purpose of this study is to explore conformational space in a series of heterocyclic cations to discover novel structural motifs that can selectively bind and stabilize specific G-quadruplex arrangements. A variety of biophysical techniques such as thermal me
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Books on the topic "DNA selectivity"

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Engel, Paul. Enzymes: A Very Short Introduction. Oxford University Press, 2020. http://dx.doi.org/10.1093/actrade/9780198824985.001.0001.

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Enzymes: A Very Short Introduction explores enzymes, the tiny molecular machines that make life possible. These proteins speed up chemical reactions inside a living organism many millionfold. Working together, teams of enzymes carry out all the processes that can be collectively recognized as life, from making DNA to digesting food. This VSI explains how this works, before going on to reveal how these catalysts of such extraordinary power and exquisite selectivity have evolved. It also examines the many varied ways in which individual enzymes are used nowadays as tools—in medical diagnosis and
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Whitley, Brandi Ristine. Anti-myc dithiophosphate DNA oligonucleotides selectively stop the growth of HL-60 cells: Systhesis, purification, and cell studies. 1999.

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Perikanan trammel net: Analisis selektivitas dan fisiologis tingkah laku ikan untuk kepentingan pengelolaannya = Trammel net fishery : selectively and fish physiological behaviour analysis for its management purpose. Departemen Pemanfaatan Sumberdaya Perikanan, Fakultas Perikanan dan Ilmu Kelautan, Institut Pertanian Bogor, 2006.

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Davis, Andrew R. Reconstructing the Temple. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780190868963.001.0001.

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This book examines temple renovation as a distinct topos within royal literature of the ancient Near East. Unlike newly founded temples, which were celebrated for their novelty, temple renovations were oriented toward the past. Kings took the opportunity to rehearse the history of the temple, selectively evoking certain past traditions and omitting others. In this way, temple renovations are a kind of historiography. The particularities of each case notwithstanding, this book demonstrates a pattern in the rhetoric of temple renovation texts; namely, kings used temple renovation to correct, or
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Book chapters on the topic "DNA selectivity"

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Guengerich, Frederick Peter. "Sequence Selectivity of DNA Damage." In Molecular Life Sciences. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4614-1531-2_214.

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Guengerich, F. Peter. "Sequence Selectivity of DNA Damage." In Molecular Life Sciences. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-6436-5_214-1.

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Travers, Andrew. "The regulation of promoter selectivity in eubacteria." In DNA-Protein Interactions. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1480-6_5.

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Hartley, John A. "Selectivity in Alkylating Agent-DNA Interactions." In Molecular Aspects of Anticancer Drug-DNA Interactions. Macmillan Education UK, 1993. http://dx.doi.org/10.1007/978-1-349-12356-8_1.

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Guengerich, Frederick Peter. "Selectivity of Chemicals for DNA Damage." In Molecular Life Sciences. Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4614-1531-2_163.

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Legendre, Franck, and Jean-Claude Chottard. "Kinetics and Selectivity of DNA-Platination." In Cisplatin. Verlag Helvetica Chimica Acta, 2006. http://dx.doi.org/10.1002/9783906390420.ch9.

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Guengerich, F. Peter. "Selectivity of Chemicals for DNA Damage." In Molecular Life Sciences. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-6436-5_163-1.

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Dostert, A., and T. Heinzel. "DNA-Dependent Cofactor Selectivity of the Glucocorticoid Receptor." In Recent Advances in Glucocorticoid Receptor Action. Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/978-3-662-04660-9_15.

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Marx, Andreas. "Chemical Biology of DNA Replication: Probing DNA Polymerase Selectivity Mechanisms with Modified Nucleotides." In The Chemical Biology of Nucleic Acids. John Wiley & Sons, Ltd, 2010. http://dx.doi.org/10.1002/9780470664001.ch3.

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Saito, I., M. Takayama, H. Sugiyama, and T. Nakamura. "Design of Photoactivatable DNA-Cleaving Amino Acids with High Sequence Selectivity." In DNA and RNA Cleavers and Chemotherapy of Cancer and Viral Diseases. Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-009-0251-0_12.

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Conference papers on the topic "DNA selectivity"

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Brieba, Luis G., Mauricio Carbajal, Luis Manuel Montaño, Oscar Rosas-Ortiz, Sergio A. Tomas Velazquez, and Omar Miranda. "Conformational Dynamics in DNA Replication Selectivity." In Advanced Summer School in Physics 2007. AIP, 2007. http://dx.doi.org/10.1063/1.2825116.

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Ramachandran, Abhijit, Qingjiang Guo, Samir Iqbal, and Yaling Liu. "Modeling DNA Translocation Kinetics in Nanopores With Selectivity." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13074.

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The development in nanotechnology has made fabrication of solid-state nanopores with 20nm diameter possible. These nanopores have found a variety of applications, with the foremost one being sensing of the biological molecules. To achieve molecular sensing, a major requirement of these solid state nanopores is molecular selectivity. This paper focuses on modeling the DNA translocation in functionalized nanopore with application on gene sequencing.
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Sasaki, Shigeki, Fumi Nagatsugi, Monsur Ali, Sayaka Mori, and Shizuka Nakayama. "Molecular design for DNA hybridization-promoted reactions with high efficiency and selectivity." In XIIIth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2005. http://dx.doi.org/10.1135/css200507115.

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Erickson, David, Xuezhu Liu, Ulrich Krull, and Dongqing Li. "An Electrokinetically Controlled DNA Hybridization Chip." In ASME 2004 2nd International Conference on Microchannels and Minichannels. ASMEDC, 2004. http://dx.doi.org/10.1115/icmm2004-2431.

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Biosensors and more specifically biochips exploit the interactions between a target analyte and an immobilized biological recognition element to produce a measurable signal. Systems based on surface phase nucleic acid hybridization, such as modern microarrays, are particularly attractive due to the high degree of selectivity in the binding interactions. One drawback of this reaction is the relatively long time required for complete hybridization to occur, as a result of the diffusion limited reaction kinetics. In this work an electrokinetically controlled DNA hybridization microfluidic chip wi
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Jackson, Paul JM, Khondaker M. Rahman, and David E. Thurston. "Abstract 5370: Use of molecular dynamics simulations to rationalise the DNA sequence-selectivity of pyrrolobenzodiazepine-MPB conjugates." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-5370.

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Musetti, Caterina, Arvind Kumar, Mohamed A. Ismail, et al. "Abstract 3219: Heterocyclic cations: Highlighting the importance of selectivity in biologically relevant quadruplex DNA recognition and binding." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-3219.

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Erickson, David, Xuezhu Liu, Roberto Venditti, Ulrich Krull, and Dongqing Li. "A DNA Hybridization Chip With Electrokinetically-Based Single Nucleotide Polymorphism (SNP) Discrimination." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-59320.

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Biosensors and more specifically biochips exploit the interactions between a target analyte and an immobilized biological recognition element to produce a measurable signal. Systems based on surface phase nucleic acid hybridization, such as modern microarrays, are particularly attractive due to the high degree of selectivity in the binding interactions. In this work an electrokinetically controlled poly(dimethylsiloxane) based DNA hybridization microfluidic chip is presented. The electrokinetic delivery technique provides the ability to dispense controlled sample sizes to the hybridization arr
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McCarthy, Conor E., Tara Dalton, and Mark Davies. "A Gravity Driven Microfluidic Platform for DNA Enrichment." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-64599.

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There is currently considerable interest in the development of microfluidic based lab-on-chip devices for sample preparation in next generation sequencing. One of these steps is DNA enrichment which often relies on conventional PCR to amplify the sample to detectable levels. To successfully automate this step, technologies are required whereby the samples are selectively inputted, thermocycled and selectively dispensed, all non invasively and therefore leading to no contamination issues. In this study such a system was created through the use of liquid-liquid plugs flowing in a gravity driven
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Inoue, Shinnosuke, Woon-Hong Yeo, Jong-Hoon Kim, et al. "Amplification-Free DNA Detection Using a Microtip-Sensor Decorated With LNA Probes for Rapid TB Screening." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-64378.

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Tuberculosis (TB) is an epidemic affecting one-third of the world’s population, mostly in developing and low-resource settings. People having active pulmonary TB are considered highly infectious; therefore, it is critical to identify and treat these patients rapidly before spreading to others. However, the most reliable TB diagnostic methods of bacterial culture or nucleic acid amplification are time-consuming and expensive. The challenge of TB diagnosis lies in highly sensitive and specific screening with low cost. Here, we present an LNA-modified microtip-sensor, which is capable of selectiv
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Wang, Shau-Chun, Hsiao-Ping Chen, and Hsueh-Chia Chang. "Entrainment of DNA and Charged Nano-Particles Using AC Electrospray." In ASME 2009 Second International Conference on Micro/Nanoscale Heat and Mass Transfer. ASMEDC, 2009. http://dx.doi.org/10.1115/mnhmt2009-18207.

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We examine our earlier finding that AC electrospray cone can preferentially entrain and concentrate low-mobility ions generated at the cone tip [Chetwani, Maheshwari and Chang, Phys Rev Lett., 101, 204501 (2008)]. Instead of tip ionization, we scrutinize entrainment effects on dispersed ionic species in the spray solution. Fluorescence images of ejected ionic species, including anionic oxide ions, organic dyes, charged nano-particles, and stained DNA from AC electrospray cone generated with a 4–5 kV source. Negatively charged species such as anionic dyes concentrate at the tip of AC spray cone
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