Relevant bibliographies by topics / DNA Sensing Element

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'DNA Sensing Element'

Author: Grafiati
Published: 6 September 2023
Last updated: 31 July 2025

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Journal articles on the topic "DNA Sensing Element"

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Williams, Ryan M., Amanda R. Kulick, Srilakshmi Yedlapalli, Louisa Battistella, Cyrus J. Hajiran, and Letha J. Sooter. "In VitroSelection of a Single-Stranded DNA Molecular Recognition Element Specific for Bromacil." Journal of Nucleic Acids 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/102968.

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Bromacil is a widely used herbicide that is known to contaminate environmental systems. Due to the hazards it presents and inefficient detection methods, it is necessary to create a rapid and efficient sensing device. Towards this end, we have utilized a stringentin vitroselection method to identify single-stranded DNA molecular recognition elements (MRE) specific for bromacil. We have identified one MRE with high affinity (Kd=9.6 nM) and specificity for bromacil compared to negative targets of selection and other pesticides. The selected ssDNA MRE will be useful as the sensing element in a fi
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Bowman, Teresa V., and Eirini Trompouki. "Sensing Stemness." Current Stem Cell Reports 7, no. 4 (2021): 219–28. http://dx.doi.org/10.1007/s40778-021-00201-w.

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Abstract Purpose of Review Hematopoietic stem cells (HSCs) are formed embryonically during a dynamic developmental process and later reside in adult hematopoietic organs in a quiescent state. In response to their changing environment, HSCs have evolved diverse mechanisms to cope with intrinsic and extrinsic challenges. This review intends to discuss how HSCs and other stem cells co-opted DNA and RNA innate immune pathways to fine-tune developmental processes. Recent Findings Innate immune receptors for nucleic acids like the RIG-I-like family receptors and members of DNA sensing pathways are e
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Booth, Marsilea Adela, Sally Ann Harbison, and Jadranka Travas-Sejdic. "Developing Polypyrrole-Based Oligonucleotide Biosensors." Materials Science Forum 700 (September 2011): 215–18. http://dx.doi.org/10.4028/www.scientific.net/msf.700.215.

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Many medical, forensic science, environmental and general scientific difficulties may be aided by the existence of suitable biosensors such as gene sensors, body fluid detection DNA sensors, disease detection DNA sensors etc. The sensor technology described here uses the conducting polymer polypyrrole (PPy) as both sensing element and transducer of sensing events. Stability and reproducibility are necessary characteristics of practical biosensors. The stability of polymers can be investigated using electrical impedance spectroscopy (EIS). This work discusses research focused towards creating a
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Cao, Zhong, Zhong Liang Xiao, Yun Lin Dai, Masao Kamahori, and Maki Shimoda. "Electrical Characteristics of Extended Gate FET Sensing Chip Constructed for Detection of DNA." Advanced Materials Research 97-101 (March 2010): 4189–92. http://dx.doi.org/10.4028/www.scientific.net/amr.97-101.4189.

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An extended gate field effect transistor (EGFET) sensing chip has been constructed by using one gold plate electrode for molecule recognition and FET part for signal transduction. By using a 70.7mV DC voltage onto a Ag/AgCl reference electrode, the electrical characteristics of immobilization of the oligonucleotide probe of P1 and hybridization with the target single strand DNA of P2 on the EGFET sensing chip were examined in detail. The electrical signals on the change of a threshold voltage (VT) shift at a constant ID (3000μA) in VG-ID characteristic were obtained, and the VT shift value due
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Balaji, Aditya, Songlin Yang, Jeslyn Wang, and Jin Zhang. "Graphene Oxide-Based Nanostructured DNA Sensor." Biosensors 9, no. 2 (2019): 74. http://dx.doi.org/10.3390/bios9020074.

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Quick detection of DNA sequence is vital for many fields, especially, early-stage diagnosis. Here, we develop a graphene oxide-based fluorescence quenching sensor to quickly and accurately detect small amounts of a single strand of DNA. In this paper, fluorescent magnetic nanoparticles (FMNPs) modified with target DNA sequence (DNA-t) were bound onto the modified graphene oxide acting as the fluorescence quenching element. FMNPs are made of iron oxide (Fe3O4) core and fluorescent silica (SiO2) shell. The average particle size of FMNPs was 74 ± 6 nm and the average thickness of the silica shell
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Hashim, U., Soon Weng Chong, and Wei-Wen Liu. "Fabrication of Silicon Nitride Ion Sensitive Field-Effect Transistor for pH Measurement and DNA Immobilization/Hybridization." Journal of Nanomaterials 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/542737.

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The fabrication of ion sensitive field-effect transistor (ISFET) using silicon nitride (Si3N4) as the sensing membrane for pH measurement and DNA is reported. For the pH measurement, the Ag/AgCl electrode was used as the reference electrode, and different pH values of buffer solution were used in the ISFET analysis. The ISFET device was tested with pH buffer solutions of pH2, pH3, pH7, pH8, and pH9. The results show that the IV characteristic of ISFET devices is directly proportional and the device’s sensitivity was 43.13 mV/pH. The ISFET is modified chemically to allow the integration with bi
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Khalil, Hilal S., Hemanth Tummala, Stoyan Chakarov, Nikolai Zhelev, and David P. Lane. "Targeting ATM pathway for therapeutic intervention in cancer." BioDiscovery 1 (July 29, 2012): e8920. https://doi.org/10.7750/BioDiscovery.2012.1.3.

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The Ataxia Telangiectasia Mutated gene encodes the ATM protein, a key element in the DNA damage response (DDR) signalling pathway responsible for maintaining genomic integrity within the cell. The ATM protein belongs to a family of large protein kinases containing the phosphatidylinositol-3 catalytic domain, including ATM, ATR and PI3K. ATM provides the crucial link between DNA damage, cell cycle progression and cell death by first sensing double stranded DNA breaks and subsequently phosphorylating and activating other downstream proteins functioning in DNA damage repair, cell cycle arrest and
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Ida, Jeunice, Soo Chan, Jörn Glökler, Yee Lim, Yee Choong, and Theam Lim. "G-Quadruplexes as An Alternative Recognition Element in Disease-Related Target Sensing." Molecules 24, no. 6 (2019): 1079. http://dx.doi.org/10.3390/molecules24061079.

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G-quadruplexes are made up of guanine-rich RNA and DNA sequences capable of forming noncanonical nucleic acid secondary structures. The base-specific sterical configuration of G-quadruplexes allows the stacked G-tetrads to bind certain planar molecules like hemin (iron (III)-protoporphyrin IX) to regulate enzymatic-like functions such as peroxidase-mimicking activity, hence the use of the term DNAzyme/RNAzyme. This ability has been widely touted as a suitable substitute to conventional enzymatic reporter systems in diagnostics. This review will provide a brief overview of the G-quadruplex arch
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Allegra, Alessandro, Claudia Petrarca, Mario Di Gioacchino, Giuseppe Mirabile, and Sebastiano Gangemi. "Electrochemical Biosensors in the Diagnosis of Acute and Chronic Leukemias." Cancers 15, no. 1 (2022): 146. http://dx.doi.org/10.3390/cancers15010146.

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Until now, morphological assessment with an optical or electronic microscope, fluorescence in situ hybridization, DNA sequencing, flow cytometry, polymerase chain reactions, and immunohistochemistry have been employed for leukemia identification. Nevertheless, despite their numerous different vantages, it is difficult to recognize leukemic cells correctly. Recently, the electrochemical evaluation with a nano-sensing interface seems an attractive alternative. Electrochemical biosensors measure the modification in the electrical characteristics of the nano-sensing interface, which is modified by
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Li, Yong, Tomoki Kimura, John H. Laity, and Glen K. Andrews. "The Zinc-Sensing Mechanism of Mouse MTF-1 Involves Linker Peptides between the Zinc Fingers." Molecular and Cellular Biology 26, no. 15 (2006): 5580–87. http://dx.doi.org/10.1128/mcb.00471-06.

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ABSTRACT Mouse metal response element-binding transcription factor-1 (MTF-1) regulates the transcription of genes in response to a variety of stimuli, including exposure to zinc or cadmium, hypoxia, and oxidative stress. Each of these stresses may increase labile cellular zinc, leading to nuclear translocation, DNA binding, and transcriptional activation of metallothionein genes (MT genes) by MTF-1. Several lines of evidence suggest that the highly conserved six-zinc finger DNA-binding domain of MTF-1 also functions as a zinc-sensing domain. In this study, we investigated the potential role of
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Dissertations / Theses on the topic "DNA Sensing Element"

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Basu, Nivedita. "Exploration of Materials and Platforms for the Development of a Label-free Electrochemical DNA Sensor." Thesis, 2017. http://etd.iisc.ac.in/handle/2005/4309.

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The aim of the studies presented in this thesis was to explore various materials and platforms for the detection of DNA in order to develop a cost-effective, repeatable and reproducible electrical/electrochemical DNA sensor. Chapter 1 is a review chapter consisting of a comparative study of the fundamental working principle, fabrication process, characteristics and performance of different types of DNA biosensors and a detailed discussion on the progress in the development of DNA biosensors. The studies described in Chapter 2 focuses on the development of a flexible, label-Free DNA Sensor
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Book chapters on the topic "DNA Sensing Element"

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Kumar, Pramod, and Sushil Kumar. "Detection of Bio-Relevant Metal Ions by Luminescent Ru(II)-Polypyridyl Based Sensors." In Ruthenium - an Element Loved by Researchers [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96453.

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Biorelevant metal ions such as Cu2+ and Fe2+/Fe3+ participate in various biological events which include electron transfer reactions, delivery and uptake of oxygen, DNA and RNA syntheses, and enzymatic catalysis to maintain fundamental physiological processes in living organisms. So far, several analytical techniques have been investigated for their precise detection; however, luminescence-based sensing is often superior due to its high sensitivity, selectivity, fast and easy operation and convenient cellular imaging. Owing to their immense photophysical and photochemical properties stemming f
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Tripathi, Abhay Dev, Soumya Katiyar, and Avinash K. Chaurasia. "Nanomaterials for Biosensing Applications." In Recent Advances in Biosensor Technology, edited by Abha Mishra. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815123739123010004.

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A biosensor is a device that detects the presence of analytes with its biological receptor entity, having unique specificities corresponding to their analytes. Most of these analytes are usually physical in nature, such as DNA, proteins, antibodies, and antigens, but they may also be simple compounds, including glucose, H2O2, toxins, and so on. Biosensors’ significance rises in providing real-time quantitative and qualitative information on analyte composition. The sensing mechanism involves the transduction of target binding interactions into optical, electrochemical signals, etc ., which can
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Wahid Anwar, Abdul, Zahid Anwar, Iqra Dildar, Nazakat Ali, Uzba, and Kashif Ahsan. "Biosensing Basics." In Biomedical Engineering. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.113771.

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The aim of this chapter is to understand biosensor basics. A biosensor is a sophisticated analytical device that uses a biological sensing component to detect biological or chemical reactions. It combines an electronic component with a biological element, producing quantifiable signals and detects physiological changes, environmental components, diseases, harmful chemicals, and pH values in various sizes and designs. Biosensors detect substances by detecting an analyte, such as glucose, creatinine, lactate, L-phenylalanine, L-alanine, pyruvate, salicylate, and urea. Biosensors, including DNA,
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Özyurt, Canan. "Recent Advances in the Use of Nucleic Acid Aptamers in Electrochemical and Optical Biosensors." In Advancements in Biosensors: Fundamentals, Technologies, and Applications. Özgür Yayınları, 2025. https://doi.org/10.58830/ozgur.pub815.c3421.

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Nucleic acid aptamers are single-stranded DNA (ssDNA) or RNA oligonucleotides that have the ability to recognize different targets with their special secondary structures. Aptamers, which have high specificity and affinity, are gaining increasing importance in biosensor technologies as recognition elements that can be easily synthesized chemically and modified according to the need. The small size, stability, easy modification and low immunogenicity of aptamers make them an important alternative to traditional antibodies as biosensor recognition elements. In this book chapter, current electroc
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Mehedi Hossain, G. M., Daniel Garza, Emilio Chavez, Ahmed Hasnain Jalal, and Fahmida Alam. "ZnO Nanowires for Biosensing Applications." In Nanotechnology and Nanomaterials. IntechOpen, 2025. https://doi.org/10.5772/intechopen.115565.

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Zinc oxide Nanowires (ZnO-NWs) are promising biosensor materials and hold the key to overcoming challenges in the field. This chapter provides an introductory overview of biosensing technology, focusing on the fundamental principles and comparing ZnO-NWs with other nanostructures regarding the surface area, reactivity, electrical properties, charge transport behavior, optical, magnetic, and piezoelectric properties, and mechanical flexibility. Providing the synthesis and characterization methods, ZnO-NWs’ biosensing processes are also elaborated on surface modification for selectivity, integra
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Conference papers on the topic "DNA Sensing Element"

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Lee, Hee-Jo, Hyun-Seok Lee, Kyung-Hwa Yoo, and Jong-Gwan Yook. "DNA sensing based on single element planar double split-ring resonator." In 2009 IEEE MTT-S International Microwave Symposium Digest (MTT). IEEE, 2009. http://dx.doi.org/10.1109/mwsym.2009.5166039.

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Gratz-Kelly, Sebastian, Benedikt Holz, Tim Krüger, et al. "An Integrated Audio-Tactile Interface Based on Dielectric Elastomer Actuators for User Interaction." In ASME 2023 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2023. http://dx.doi.org/10.1115/smasis2023-111228.

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Abstract Due to their high actuation energy density, high stretchability and self-sensing capability, dielectric elastomer actuators (DEAs) and sensors are very attractive for the field of user interaction and communication. The possibility of using the same element to perform actuation (feedback) and sensing (user input detection), in particular, opens up possibilities towards highly integrated interaction elements. Here, we present an integrated prototype of a DEA user interface that can produce different feedbacks (acoustic, vibrotactile) in response to a user’s touch. Touch detection is ac
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Lopez-Reyna, C. E., and J. N. Zemel. "The Road to Smart Transducer Technology." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-33179.

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The past decade has seen three distinct trends emerge in sensor technologies. The first is biosensing wherein measurements as diverse as detecting aromas in food processing to highly sophisticated detection of DNA and proteins have become staples of contemporary engineering efforts. The second important trend is the continuing decrease in the physical size of sensing elements embodied by the replacement of “micro” by “nano” in fabrication and technology. These two efforts in biosensing and the decreasing size of electronic and sensing components have transformed not only virtually every area o
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Choi, Junseo, Bahador Farshchian, and Sunggook Park. "Fabrication of Perforated Conical Nanopores in Freestanding Polymer Membranes Using Nanoimprint Lithography and Pressed Self-Perfection Method." In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-87669.

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Nanopores have proven to be an important sensing element in biosensors to detect and analyze single biomolecules such as DNAs, RNAs, or proteins. The charged biomolecules are driven by an electric field and detected as transient current blocks associated with their translocation through the pores. While protein nanopores, such as alpha-hemolysin and MspA protein nanopores embedded within a lipid bilayer membrane [1], promise to be a rapid, sensitive and label-free sensing paradigm, their duration of usage is too short to perform repetitive experiments due to the mechanical instability of the l
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Maschmann, Matthew R., Gregory J. Ehlert, and Jeffery W. Baur. "Piezoresistive Reponse of Aligned Carbon Nanotube Arrays for Flow Sensing Applications." In ASME 2011 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. ASMEDC, 2011. http://dx.doi.org/10.1115/smasis2011-5096.

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We investigate the electromechanical sensing capabilities of aligned carbon nanotube (CNT) arrays as a means for a lightweight and simple electromechanical transduction element. CNT array heights of 25 and 350 μm are examined using a modified dynamic mechanical analyzer (DMA) to impart multiple strain-based test configurations while simultaneously measuring electrical resistance. Observed gauge factors range from 12.5 for the 25μm array to greater than 190 for the 350 μm array, with a peak sensitivity of 13,750 ohms/gram force achieved for the 350 μm array. The electromechanical response obser
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Li, Leslie, Richard Burton, and Greg Schoenau. "Feasibility Study on the Use of Dynamic Neural Networks (DNN’s) for Modeling a Variable Displacement Load Sensing Pump." In ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-15588.

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The feasibility of using a particular form of neural networks, defined as Dynamic Neural Units (DNU's), to model a pump in a load sensing system is investigated in this paper. Because of the highly complex structure of the pump, its compensators and controlling elements, simulation of load-sensing pump systems pose many challenges to researchers. Several models of pumps, compensators and valves have been developed and published in the literature but they are overly simplified or are in an extremely complex form. One modeling approach which can capture the nonlinear dynamic properties of the pu
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