Academic literature on the topic 'DNA – Structure ; Nanostructures'

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Journal articles on the topic "DNA – Structure ; Nanostructures"

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Lin, Chenxiang, Sherri Rinker, Xing Wang, Yan Liu, Nadrian C. Seeman, and Hao Yan. "In vivo cloning of artificial DNA nanostructures." Proceedings of the National Academy of Sciences 105, no. 46 (2008): 17626–31. http://dx.doi.org/10.1073/pnas.0805416105.

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Mimicking nature is both a key goal and a difficult challenge for the scientific enterprise. DNA, well known as the genetic-information carrier in nature, can be replicated efficiently in living cells. Today, despite the dramatic evolution of DNA nanotechnology, a versatile method that replicates artificial DNA nanostructures with complex secondary structures remains an appealing target. Previous success in replicating DNA nanostructures enzymatically in vitro suggests that a possible solution could be cloning these nanostructures by using viruses. Here, we report a system where a single-stran
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Pan, Keyao, Etienne Boulais, Lun Yang, and Mark Bathe. "Structure-based model for light-harvesting properties of nucleic acid nanostructures." Nucleic Acids Research 42, no. 4 (2013): 2159–70. http://dx.doi.org/10.1093/nar/gkt1269.

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Abstract Programmed self-assembly of DNA enables the rational design of megadalton-scale macromolecular assemblies with sub-nanometer scale precision. These assemblies can be programmed to serve as structural scaffolds for secondary chromophore molecules with light-harvesting properties. Like in natural systems, the local and global spatial organization of these synthetic scaffolded chromophore systems plays a crucial role in their emergent excitonic and optical properties. Previously, we introduced a computational model to predict the large-scale 3D solution structure and flexibility of nucle
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Han, Dongran, Xiaodong Qi, Cameron Myhrvold, et al. "Single-stranded DNA and RNA origami." Science 358, no. 6369 (2017): eaao2648. http://dx.doi.org/10.1126/science.aao2648.

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Self-folding of an information-carrying polymer into a defined structure is foundational to biology and offers attractive potential as a synthetic strategy. Although multicomponent self-assembly has produced complex synthetic nanostructures, unimolecular folding has seen limited progress. We describe a framework to design and synthesize a single DNA or RNA strand to self-fold into a complex yet unknotted structure that approximates an arbitrary user-prescribed shape. We experimentally construct diverse multikilobase single-stranded structures, including a ~10,000-nucleotide (nt) DNA structure
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Poppleton, Erik, Joakim Bohlin, Michael Matthies, Shuchi Sharma, Fei Zhang, and Petr Šulc. "Design, optimization and analysis of large DNA and RNA nanostructures through interactive visualization, editing and molecular simulation." Nucleic Acids Research 48, no. 12 (2020): e72-e72. http://dx.doi.org/10.1093/nar/gkaa417.

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Abstract This work seeks to remedy two deficiencies in the current nucleic acid nanotechnology software environment: the lack of both a fast and user-friendly visualization tool and a standard for structural analyses of simulated systems. We introduce here oxView, a web browser-based visualizer that can load structures with over 1 million nucleotides, create videos from simulation trajectories, and allow users to perform basic edits to DNA and RNA designs. We additionally introduce open-source software tools for extracting common structural parameters to characterize large DNA/RNA nanostructur
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Piskunen, Petteri, Sami Nummelin, Boxuan Shen, Mauri A. Kostiainen, and Veikko Linko. "Increasing Complexity in Wireframe DNA Nanostructures." Molecules 25, no. 8 (2020): 1823. http://dx.doi.org/10.3390/molecules25081823.

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Structural DNA nanotechnology has recently gained significant momentum, as diverse design tools for producing custom DNA shapes have become more and more accessible to numerous laboratories worldwide. Most commonly, researchers are employing a scaffolded DNA origami technique by “sculpting” a desired shape from a given lattice composed of packed adjacent DNA helices. Albeit relatively straightforward to implement, this approach contains its own apparent restrictions. First, the designs are limited to certain lattice types. Second, the long scaffold strand that runs through the entire structure
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Poppleton, Erik, Roger Romero, Aatmik Mallya, Lorenzo Rovigatti, and Petr Šulc. "OxDNA.org: a public webserver for coarse-grained simulations of DNA and RNA nanostructures." Nucleic Acids Research 49, W1 (2021): W491—W498. http://dx.doi.org/10.1093/nar/gkab324.

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Abstract OxDNA and oxRNA are popular coarse-grained models used by the DNA/RNA nanotechnology community to prototype, analyze and rationalize designed DNA and RNA nanostructures. Here, we present oxDNA.org, a graphical web interface for running, visualizing and analyzing oxDNA and oxRNA molecular dynamics simulations on a GPU-enabled high performance computing server. OxDNA.org automatically generates simulation files, including a multi-step relaxation protocol for structures exported in non-physical states from DNA/RNA design tools. Once the simulation is complete, oxDNA.org provides an inter
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Henning-Knechtel, Anja, Matthew Wiens, Mathias Lakatos, et al. "Dielectrophoresis of gold nanoparticles conjugated to DNA origami structures." Beilstein Journal of Nanotechnology 7 (July 1, 2016): 948–56. http://dx.doi.org/10.3762/bjnano.7.87.

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DNA nanostructures are promising construction materials to bridge the gap between self-assembly of functional molecules and conventional top-down fabrication methods in nanotechnology. Their positioning onto specific locations of a microstructured substrate is an important task towards this aim. Here we study manipulation and positioning of pristine and of gold nanoparticle-conjugated tubular DNA origami structures using ac dielectrophoresis. The dielectrophoretic behavior was investigated employing fluorescence microscopy. For the pristine origami, a significant dielectrophoretic response was
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Kim, Jeonghun, So Yeon Ahn, and Soong Ho Um. "Bead-Immobilized Multimodal Molecular Beacon-Equipped DNA Machinery for Specific RNA Target Detection: A Prototypical Molecular Nanobiosensor." Nanomaterials 11, no. 6 (2021): 1617. http://dx.doi.org/10.3390/nano11061617.

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A variety of nanostructured diagnostic tools have been developed for the precise detection of known genetic variants. Molecular beacon systems are very promising tools due to their specific selectivity coupled with relatively lower cost and time requirements than existing molecular detection tools such as next generation sequencing or real-time PCR (polymerase chain reaction). However, they are prone to errors induced by secondary structure responses to environmental fluctuations, such as temperature and pH. Herein, we report a temperature-insensitive, bead-immobilized, molecular beacon-equipp
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Bayrak, Türkan, Nagesh Jagtap, and Artur Erbe. "Review of the Electrical Characterization of Metallic Nanowires on DNA Templates." International Journal of Molecular Sciences 19, no. 10 (2018): 3019. http://dx.doi.org/10.3390/ijms19103019.

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The use of self-assembly techniques may open new possibilities in scaling down electronic circuits to their ultimate limits. Deoxyribonucleic acid (DNA) nanotechnology has already demonstrated that it can provide valuable tools for the creation of nanostructures of arbitrary shape, therefore presenting an ideal platform for the development of nanoelectronic circuits. So far, however, the electronic properties of DNA nanostructures are mostly insulating, thus limiting the use of the nanostructures in electronic circuits. Therefore, methods have been investigated that use the DNA nanostructures
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Glaser, Martin, Sourav Deb, Florian Seier, et al. "The Art of Designing DNA Nanostructures with CAD Software." Molecules 26, no. 8 (2021): 2287. http://dx.doi.org/10.3390/molecules26082287.

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Since the arrival of DNA nanotechnology nearly 40 years ago, the field has progressed from its beginnings of envisioning rather simple DNA structures having a branched, multi-strand architecture into creating beautifully complex structures comprising hundreds or even thousands of unique strands, with the possibility to exactly control the positions down to the molecular level. While the earliest construction methodologies, such as simple Holliday junctions or tiles, could reasonably be designed on pen and paper in a short amount of time, the advent of complex techniques, such as DNA origami or
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Dissertations / Theses on the topic "DNA – Structure ; Nanostructures"

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Wickham, Shelley. "DNA origami : a substrate for the study of molecular motors." Thesis, University of Oxford, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.561126.

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DNA origami is a method for constructing 2-dimensional nanostructures with arbitrary shapes, by folding a long piece of viral genomic DNA into an extended pattern (Rothemund, 2006). In this thesis DNA origami nanostructures that in- corporate active transport are developed, by combining rectangular DNA origami tiles with either synthetic DNA motors, or the protein motor F1-ATPase. The transport of an autonomous, unidirectional, and processive 'burnt-bridges' DNA motor across an extended linear track anchored to a DNA origami tile is demonstrated. Ensemble fluorescence measurements are used to
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Teixeira, da Silva Emerson Rodrigo. "Structure and dynamics of DNA confined in-between non-cationic lipid membranes." Thesis, Bordeaux 1, 2011. http://www.theses.fr/2011BOR14342/document.

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Une étude expérimentale sur la structure et la dynamique d'un complexe hydraté de fragments d'ADN (150 pb) et des phases lamellaires de lipides non-cationiques est présentée. Par la variation de d'hydratation, il est possible de contrôler le confinement imposé par cette matrice hôte sur les nucléotides insérés dans les couches aqueuses. L’organisation supramoléculaire du complexe est suivie par diffraction des rayons-X et des techniques de microscopie optique et électronique. Un riche polymorphisme de mésophases est observé en fonction du confinement. Dans le régime plus hydraté, les fragments
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Shtogun, Yaroslav. "Properties of Carbon Nanotubes Under External Factors: Adsorption, Mechanical Deformations, Defects, and External Electric Fields." Scholar Commons, 2010. https://scholarcommons.usf.edu/etd/1771.

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Carbon nanotubes have unique electronic, optical, mechanical, and transport properties which make them an important element of nanoscience and nanotechnology. However, successful application and integration of carbon nanotubes into new nanodevices requires fundamental understanding of their property changes under the influence of many external factors. This dissertation presents qualitative and quantitative theoretical understanding of property changes, while carbon nanotubes are exposed to the deformations, defects, external electric fields, and adsorption. Adsorption mechanisms due to Van de
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Tan, Mengmeng. "Structural optimization of polypod-like structured DNA based on structural analysis and interaction with cells." Kyoto University, 2020. http://hdl.handle.net/2433/253233.

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Hamblin, Graham. "Practical designs for DNA nanostructures: balancing minimal design and structural complexity." Thesis, McGill University, 2014. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=123134.

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Self-assembled nanostructures provide an exciting opportunity to generate new materials with molecular resolution, and in a massively parallel fashion. Nanomaterials often display unique properties relative to their bulk analogues, giving them attractive potential in fields like electronics, photonics, structural biology, and therapeutics. DNA, beyond its role in genetics, is also one of the best self-assembling molecules known. It uses specific base-pairing interactions to come together into a well-defined, rigid double helix. We can therefore predict exactly how two different strands of DNA
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Khoder, Rabih. "Elaboration de biocapteurs électrochimiques d'ADN à base de nano-structure de polypyrrole pour le diagnostic de la tuberculose." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLS094/document.

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La tuberculose est une maladie contagieuse qui s’attaque habituellement aux poumons, mais parfois aussi à d’autres parties du corps, comme les reins, les ganglions et les os. La tuberculose tue près 1,8 millions de personnes chaque année dans le monde. Il y a par conséquent un besoin urgent de mettre des moyens analytiques pour détecter l’ADN de la bactérie Mycobacterium tuberculosis, responsable de la propagation de la tuberculose. La recherche développée dans le cadre de cette thèse consiste en l'élaboration d'un outil de diagnostic pour la détection d’ADN génomique de bactérie M.Tuberculosi
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Zhu, Jinhao. "Uniquimer 3D, a software system for structural DNA nanotechnology design, analysis and evaluation /." View abstract or full-text, 2008. http://library.ust.hk/cgi/db/thesis.pl?CSED%202008%20ZHU.

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Coilhac, Clothilde. "Thermodynamique de l'assemblage de nano-structures et d'origami d'ADN." Thesis, Université Grenoble Alpes (ComUE), 2018. http://www.theses.fr/2018GREAY007/document.

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L’ADN (acide désoxyribonucléique) est le support de notre génome, c'est aussi un biopolymère dont les propriétés d’hybridation de deux simples brins complémentaires en une double hélice permettent son utilisation comme brique élémentaire pour l’auto-assemblage de structures avec une résolution de quelques nanomètres. Parmi les différentes méthodes développées, l'origami d’ADN dans lequel un simple brin d’ADN issu du génome d’un phage est replié algorithmiquement par un ensemble de brins synthétiques plus petits s'est démontré très robuste pour l'assemblage de structures bi ou tridimensionnelle
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Ramakrishnan, Saminathan [Verfasser]. "Atomic force microscopy studies of DNA origami nanostructures: from structural stability to molecular patterning / Saminathan Ramakrishnan." Paderborn : Universitätsbibliothek, 2018. http://d-nb.info/1164076272/34.

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Agarwal, Nayan Pawan [Verfasser], Thorsten-Lars [Gutachter] Schmidt, and Alexander [Gutachter] Eychmüller. "Block copolymer micellization, and DNA polymerase-assisted structural transformation of DNA origami nanostructures / Nayan Pawan Agarwal ; Gutachter: Thorsten-Lars Schmidt, Alexander Eychmüller." Dresden : Technische Universität Dresden, 2019. http://d-nb.info/1226902502/34.

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Books on the topic "DNA – Structure ; Nanostructures"

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I, Salyanov V., and Skuridin S. G, eds. Nanostructures and nanoconstructions based on DNA. Taylor & Francis, 2012.

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Narlikar, A. V., and Y. Y. Fu, eds. Oxford Handbook of Nanoscience and Technology. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199533053.001.0001.

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This Handbook presents important developments in the field of nanoscience and technology, focusing on the advances made with a host of nanomaterials including DNA and protein-based nanostructures. Topics include: optical properties of carbon nanotubes and nanographene; defects and disorder in carbon nanotubes; roles of shape and space in electronic properties of carbon nanomaterials; size-dependent phase transitions and phase reversal at the nanoscale; scanning transmission electron microscopy of nanostructures; the use of microspectroscopy to discriminate nanomolecular cellular alterations in
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Santos, Abel, and Dusan Losic. Nanoporous Alumina: Fabrication, Structure, Properties and Applications. Springer, 2016.

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Triberis, Georgios P. The Physics of Low-Dimensional Structures: From Quantum Wells to DNA and Artificial Atoms. Nova Science Pub Inc, 2006.

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Book chapters on the topic "DNA – Structure ; Nanostructures"

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Fischler, Monika, Melanie Homberger, and Ulrich Simon. "DNA-Mediated Assembly of Metal Nanoparticles: Fabrication, Structural Features, and Electrical Properties." In Nanostructure Science and Technology. Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-09459-5_2.

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Decher, G., J. D. Hong, K. Lowack, Y. Lvov, and J. Schmitt. "Layer-by-Layer Adsorption: The Solid/Liquid-Interface as a Template for the Controlled Growth of Well-Defined Nanostructures of Polyelectrolytes, Proteins, DNA and Polynucleotides." In Self-Production of Supramolecular Structures. Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0754-9_23.

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Sharma, Jaswinder, Yan Liu, and Hao Yan. "STRUCTURAL DNA NANOTECHNOLOGY: INFORMATION GUIDED SELF-ASSEMBLY." In The Chemistry of Nanostructured Materials. WORLD SCIENTIFIC, 2011. http://dx.doi.org/10.1142/9789814313070_0003.

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Conference papers on the topic "DNA – Structure ; Nanostructures"

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Saadat-Moghaddam, Darius, and Jong-Hoon Kim. "Electrolyte-Free Nano-Electronic Sensor for the Rapid Quantification of DNA." In ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-67622.

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Electric detection using a nanocomponent could lead to platforms for rapid and simple biosensing. Sensors composed of nanostructures have been described for applications requiring high sensitivity on account of their confined geometries. However, both fabrication and use of nanostructured sensors remain challenging. Here, we present a nano-electronic sensor, used as an amperometric biosensor, for the highly sensitive quantification of DNA. The proposed nano-electronic sensor is fabricated by a two-step process; 1) fabricate microscale-cantilever structure using ultraviolet (UV) lithography and
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Kannan, Balaji, and Arun Majumdar. "Novel Microfabrication Techniques for Highly Specific Programmed Assembly of Nanostructures." In ASME 2004 3rd Integrated Nanosystems Conference. ASMEDC, 2004. http://dx.doi.org/10.1115/nano2004-46053.

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Chemically synthesized nanostructures such as nanowires1, carbon nanotubes2 and quantum dots3 possess extraordinary physical, electronic and optical properties that are not found in bulk matter. These characteristics make them attractive candidates for building subsequent generations of novel and superior devices that will find application in areas such as electronics, photonics, energy and biotechnology. In order to realize the full potential of these nanoscale materials, manufacturing techniques that combine the advantages of top-down lithography with bottom-up programmed assembly need to be
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Walker, D. G., and M. A. Stremler. "Characterization of Chaotic Motion of DNA in Linear Shear Flows." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-43699.

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Motion of macromolecules in flows is important to several disciplines such as DNA hybridization studies, self assembly of nanostructures, and transport of suspensions. The present study simulates the motion of macromolecular structures in linear shear flows. A molecular chain is modeled as a coarse-grained series of beads and springs. For a wide range flow conditions, the flow appears chaotic, where quasi-stable limit cycles are observed for several smaller ranges of flow conditions.
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Olton, Dana, Dong Hyun Lee, Charles Sfeir, and Prashant N. Kumta. "Novel Nanostructured Calcium Phosphate Based Delivery Systems for Non-Viral Gene Delivery." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176286.

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Calcium phosphate (CaP) based approaches remain an attractive option for delivering plasmid DNA (pDNA) into cultured cells [1, 2]. However, two major limitations associated with this vector exist. First, it yields lower transfection efficiencies with respect to its’ viral counterparts. Second, CaP mediated gene delivery leads to transient transgene expression. Thus, we hypothesized that these concerns could respectively be addressed by: (1) synthesizing particles with precise control of the materials’ parameters including (i.e. Ca/P ratio, particle size, crystal structure, and microstructure)
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Williams, Keith A. "Towards DNA-Mediated Self Assembly of Carbon Nanotube Molecular Devices." In STRUCTURAL AND ELECTRONIC PROPERTIES OF MOLECULAR NANOSTRUCTURES: XVI International Winterschool on Electronic Properties of Novel Materials. AIP, 2002. http://dx.doi.org/10.1063/1.1514159.

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Mertig, M. "Nucleation and Growth of Metal Clusters on a DNA template." In STRUCTURAL AND ELECTRONIC PROPERTIES OF MOLECULAR NANOSTRUCTURES: XVI International Winterschool on Electronic Properties of Novel Materials. AIP, 2002. http://dx.doi.org/10.1063/1.1514160.

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Hussain, Farzana, Derrick Dean, and Anwarul Haque. "Structures and Characterization of Organoclay-Epoxy-Vinylester Nanocomposites." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-33552.

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The field of polymer-clay nanocomposites has attracted considerable attention as a method of enhancing polymer properties and extending their utility. Layered silicates dispersed as a reinforcing phase in a polymer matrix are one of the most important forms of such inorganic-organic nanocomposites, making them the subject of intense research. We have recently prepared several thermoset-based nanocomposites with improved thermal and mechanical properties. This paper is primarily focused in studying the effects of nano clay particles such as montmorillonite on improving mechanical and thermal pr
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Basak, Sudipta, and Arvind Raman. "Dynamics of Microcantilevers Tapping on Nanostructures in Liquid Environments in the Atomic Force Microscope." In ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-15479.

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The Atomic Force Microscope (AFM) has become an indispensable tool in biology because it permits the probing of nanomechanical properties under physiological (liquid environments) conditions. AFM has been used in liquid environments to image, manipulate and probe atoms, living cells, bacteria, viruses, subcellular structures such as microtubules, individual proteins and DNA. Probably the most popular method used for AFM in liquids is the tapping mode wherein a resonant microcantilever is scanned over a sample. Yet very little is known about the dynamics of microcantilevers in liquid environmen
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