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1

Freire, Izaura Luzia Silverio. "Fatores associados ? efetividade da doa??o de ?rg?os e tecidos para transplantes." Universidade Federal do Rio Grande do Norte, 2013. http://repositorio.ufrn.br:8080/jspui/handle/123456789/14763.

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The transplantation of organs and tissues presents itself as an important therapeutic option, both from a medical standpoint, the social or economic. Thus, the identification of variables that can interfere in the effectiveness of organs and tissues donation for transplantation needs to be investigated adequately, because it stands before increasing index of chronic and degenerative diseases in the population, what makes the waiting list for transplantation grow disproportionately and patients come to death without the opportunity of realization the treatment due to a lack of donors. In this context, has defined as objective of this study evaluate the factors associated with the effectiveness of organs and tissues donation for transplantation. It is a evaluative research, quantitative, prospective, with longitudinal design, developed at Central of Catchment, Notification and organ donation for transplant, Organ Procurement Organization and in six accredited hospitals to collect and transplantation of organs and tissues, in Natal/RN, between august 2010 and february 2011, after the approval of the Research Ethics Committee, under No. 414/10 and CAAE 007.0.294.000-10. The probabilistic sample without replacement was composed of 65 potential donors. It was used as an instrument of data collection a structured script non-participant observation of checklist type. Data were analyzed using descriptive statistics and presented in tables, charts, graphs and figures. For this, was used Microsoft Excel 2007 and statistical program SPSS version 20.0. To check the level of significance was chosen by applying the chi-square test (χ2) and Mann Whitney and caselas for less than five, it is considered the Fisher exact test. It was adopted as the significance level p-value <0.05. Among the surveyed it was observed that most of the individuals were male (50,8%), in the age group 45 years (53,8%), mean age of 42,3 years, minimum 5 and maximum 73 years (? 17,32 years). Single / widowers / divorced (56,9%), with up to completed elementary school (60,0%) in the exercise of professional activity (86,2%), catholic (83,1%) and residents in metropolitan region of Natal (52,3%). Was obtained donation effectiveness of 27,7%. There was no statistical significance between structure and effectiveness of the donation, but were observed inadequacies in physical resources (36,9%), materials (30,8%), organizational structure (29,2%) and human resources (18,5%). In the process, the maintenance phase (p= 0.004), diagnosis of brain death (p= 0.032), family interview (p≤ 0.001) and documentation (p= 0.001) presented statistical significance with effectiveness. Thus, it is accepts the alternative hypothesis of the study, in which is evidenced that the adequacy of the factors related to structure and process is associated to effectiveness of organs and tissues donation for transplantation. In this way, the effectiveness of organ and tissue donation ends in an essential way the rapidity and accuracy with which the donation process is conducted, requiring appropriate structure, with appropriate physical and material resources and skilled human resources to optimize the reduction of time and the suffering of those waiting for an organ or tissue transplant queued in Brazil
O transplante de ?rg?os e tecidos apresenta-se como importante op??o terap?utica, tanto do ponto de vista m?dico, quanto social ou econ?mico. Assim, a identifica??o das vari?veis que podem interferir na efetividade da doa??o de ?rg?os e tecidos para transplante precisa ser investigada de maneira adequada, pois se est? diante de crescente ?ndice de doen?as cr?nicas e degenerativas na popula??o, que faz com que a lista de espera para transplante aumente desproporcionalmente e os pacientes chegam ao ?bito sem a oportunidade de realiza??o do tratamento devido ao d?ficit de doadores. Nesse contexto, definiu-se como objetivo deste estudo avaliar os fatores associados ? efetividade da doa??o de ?rg?os e tecidos para transplantes. Trata-se de pesquisa avaliativa, quantitativa, prospectiva, com delineamento longitudinal, desenvolvida na Central de Capta??o, Notifica??o e Doa??o de ?rg?os para transplantes, Organiza??o de Procura de ?rg?os e em seis unidades hospitalares credenciadas para capta??o e transplante de ?rg?os e tecidos, em Natal/RN, entre agosto de 2010 e fevereiro de 2011, ap?s a aprova??o do projeto de pesquisa pelo Comit? de ?tica em Pesquisa, CAAE 007.0.294.000-10. A amostra probabil?stica sem reposi??o foi composta de 65 potenciais doadores. Utilizou-se como instrumento de coleta de dados um roteiro estruturado de observa??o n?o participante do tipo checklist. Os dados foram analisados por meio da estat?stica descritiva e apresentados em forma de tabelas, quadros, gr?ficos e figuras. Para tanto, utilizou-se o Microsoft Excel 2007 e o Programa Estat?stico SPSS vers?o 20.0. Para verificar o n?vel de signific?ncia optou-se pela aplica??o dos testes Qui-quadrado (χ2) e Mann Whitney e, para as caselas inferiores a cinco, considerou-se o teste exato de Fisher. Adotou-se como n?vel de signific?ncia p-valor <0,05. Entre os pesquisados observou-se que a maior parte dos indiv?duos era do sexo masculino (50,8%), na faixa et?ria at? 45 anos (53,8%), com m?dia de idade de 42,3 anos, m?nimo de cinco e m?ximo de 73 anos (? 17,32 anos). Solteiros/vi?vos/divorciados (56,9%), com at? o ensino fundamental completo (60,0%), em exerc?cio de atividade profissional (86,2%), cat?licos (83,1%) e residentes na regi?o metropolitana de Natal (52,3%). Obteve-se efetividade de doa??o de 27,7%. N?o ocorreu signific?ncia estat?stica entre a estrutura e a efetividade da doa??o, por?m observaram-se inadequa??es nos recursos f?sicos (36,9%), materiais (30,8%), estrutura organizacional (29,2%) e recursos humanos (18,5%). No processo, as fases de manuten??o (p=0,004), diagn?stico de morte encef?lica (p=0,032), entrevista familiar (p≤ 0,001) e documenta??o (p= 0,001) apresentaram signific?ncia estat?stica com a efetividade. Assim, se aceita a hip?tese alternativa do estudo, na qual se evidencia que a adequa??o dos fatores relacionados ? estrutura e processo est? associada ? efetividade da doa??o de ?rg?os e tecidos para transplantes. Desse modo, a efetividade da doa??o de ?rg?os e tecidos encerra de forma imprescind?vel a rapidez e a precis?o com que o processo de doa??o se conduz, requerendo estrutura adequada, com recursos f?sicos e materiais apropriados e recursos humanos capacitados, para otimizar a diminui??o do tempo e do sofrimento daqueles que aguardam um ?rg?o ou tecido na fila do transplante no Brasil
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2

?vila, Gustavo Noronha de. "Da esperan?a aos dilemas : doa??o e com?rcio de ?rg?os humanos." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2007. http://tede2.pucrs.br/tede2/handle/tede/4994.

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A disserta??o visou abordar os procedimentos de transplanta??o humana, especificamente a tutela penal relativa ao com?rcio de ?rg?os humanos que tem sido dispensada n?o s? pelo legislador p?trio (Lei 9.434/97), como tamb?m em rela??o ao direito comparado a esta revolucion?ria t?cnica. Tal objetivo foi desenvolvido atrav?s de an?lise eminentemente interdisciplinar, com a abordagem de elementos da hist?ria das id?ias, psiquiatria, filosofia, etnografia, bio?tica e direito. Primeiramente buscou-se investigar a transi??o das vis?es de corpo na modernidade e contemporaneidade: indo desde uma id?ia de sacralidade at? a de profana??o. Ap?s, buscou-se, al?m da realiza??o de an?lise hist?rico-comparativa dos principais avan?os cient?ficos na ?rea com a evolu??o legislativa, principalmente em nosso pa?s, a defini??o de conceitos relacionados ? tem?tica, como o de transplante, suas modalidades e a pol?mica relativa a morte encef?lica. A quest?o de escassez demonstrou-se essencial ? discuss?o, j? que ensejadora de um dos mais debatidos e controversos temas relativos aos transplantes de ?rg?o na atualidade: o com?rcio de ?rg?os humanos. Ap?s discuss?o de casos documentados sobre a pr?tica, foi realizada a confronta??o entre os argumentos favor?veis e contr?rios, chegando-se ? conclus?o de que uma an?lise ? luz da dignidade humana e da ?tica da alteridade ? suficiente para recha?ar a disposi??o remunerada de ?rg?os humanos. Sob a ?tica dos bens jur?dicos envolvidos e do consentimento do ofendido, a conclus?o n?o ? outra. Por ?ltimo atrav?s de pesquisa de campo em que foram entrevistadas 450 pessoas, evidenciou-se a avers?o majorit?ria ao com?rcio de ?rg?os, fundada em um crit?rio moral, em tr?s grupos diferentes (profissionais e acad?micos de Medicina e outras ci?ncias da sa?de; profissionais e acad?micos do Direito e comunidade em geral). O desejo de salvar vidas precisa estar em conson?ncia com o necess?rio respeito ? dignidade humana.
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3

Dantas, Herlaine Roberta Nogueira. "Dos direitos da personalidade e a lei de doa??o de ?rg?os: o que h? para cartografar?" Universidade Federal do Rio Grande do Norte, 2010. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13218.

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This study aimed at examining the representation and the level of knowledge as well as getting acquainted whether there had been significant divergence among three social groups of 3rd year Law students, 7th period Medical students at UFPB and a group of people from the Catholic Church in vila dos pescadores in Jo?o Pessoa - about organ donation, transplant law and ethical issues that raise questions. In order to accomplish the qualitative analysis, Bardin?s content analysis technique was applied in conjunction with the Chisquare test which was applied with significance level of 5% to quantitative data. The data revealed that most informants agree with organ donation, Although they are not acquainted with the law of transplants, and with the lack of confidence in the single list of recipients. The problem is that there is an encouragement to trades with organs and the possibility of any person legally authorized to donate organs in life. The statistically significant difference was observed in only two questions, ie, in response to the confidence in the diagnosis of brain death: 64% of 7th period Medical students at UFPB trust this diagnosis versus 12% of the evangelizing group of vila dos pescadores. The other difference refers to the answer about the confidence in the single list of recipients: 36% of the 7th period Medical students of UFPB said to trust the list versus 12% of the 3rd law students of UFPB. This is was a multidisciplinary study with Involvement of lawyers and doctors
O presente estudo teve por objetivo analisar a representa??o, o n?vel de conhecimento, bem como saber se existia diverg?ncia significativa entre tr?s grupos sociais estudantes de direito do 3? ano e de medicina do 7? per?odo da UFPB e um grupo de pessoas da igreja cat?lica na vila dos pescadores em Jo?o Pessoa-PB sobre a doa??o de ?rg?os, lei dos transplantes e temas que suscitam questionamentos ?ticos. Aplicou-se a t?cnica de an?lise de conte?do de Bardin para a an?lise qualitativa e o teste Qui-quadrado com n?vel de signific?ncia de 5% para os dados quantitativos. Os dados mostraram que a maioria dos entrevistados ? favor?vel a doa??o de ?rg?os, que n?o conhece a lei de transplantes, como tamb?m n?o confia na lista ?nica de receptores. E que h? um favorecimento ao com?rcio de ?rg?os, a possibilidade de qualquer pessoa autorizada judicialmente ser doador de ?rg?os em vida. A diferen?a estatisticamente significativa s? foi observada em dois questionamentos, ou seja, na resposta sobre a confian?a no diagn?stico de morte encef?lica: 64% dos estudantes de medicina do 7? per?odo da UFPB confiam nesse diagn?stico versus 12% do grupo evangelizador da vila dos pescadores. A outra diferen?a foi na resposta sobre a confian?a na lista ?nica de receptores: 36% dos estudantes do 7? per?odo de medicina da UFPB afirmaram confiar na lista versus 12% dos estudantes de direito do 3? ano da UFPB. A realiza??o desse estudo teve car?ter multidisciplinar com envolvimento de advogados e m?dicos
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4

Heinzen, Evelyn. "An??lise dos ??rg??os ofertados ?? Central Nacional de Transplantes (CNT) provenientes de doadores idosos." Universidade Cat??lica de Bras??lia, 2015. https://bdtd.ucb.br:8443/jspui/handle/tede/2075.

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Organ transplantation is one of the greatest twentieth century advances in medicine, with success rates above 80%. Recent changes on donors profile, due to worldwide population aging, has led to modified organs acceptance criteria by the transplantation centers. This study aimed to describe the epidemiological, serological and clinical data of elderly organ donors, aged 60 years old or above, distributed by the National Transplant Center - NTC, Brazil, from 2011 to 2014, with special regard to organ donations progression and donation processes outcome related to the elderly organs donors. A descriptive, exploratory, retrospective, temporal and documentary series study was conducted with secondary data concerning Brazilian Federal Unit origin (UF), donation processes data and solid organs (heart, lung, liver and kidney) distribution, conducted by NTC, from 2011 to 2014, of older donors with 60 years or above. A total of 1,173 donation processes were analyzed, 38.6% of elderly donors were 60-64 years range and 31.5% were 65-69 years range. 57.9% were men and stroke (haemorrhagic) was the leading cause of death. Santa Catarina (20.2%), Cear?? (13%) and Rio de Janeiro (11.3%) were the most tendered states for national elderly organs distribution. Kidney was the most offered organ, followed by liver, heart and lung, in that order. Potential donor hospital stay was identified as an average of 5 - 6 days. Considering the use of vasoactive drugs and antibiotics, there was not a significant difference between donors with transplanted organs and donors with discarded organs. As for serologic tests, the presence or absence of a positive serologic test did not influence the acceptance of organs; however creatinine, urea and total bilirubin levels influenced this acceptance. Our results suggests that further researches are needed to better understand the old organ donor profile, consequently stimulating the use of organs from these donors by the transplantation centers and state transplant centers.
O transplante de ??rg??os foi um dos maiores avan??os obtidos pela medicina no s??culo XX, com ??ndice de sucesso acima de 80%. A mudan??a no perfil do doador, devido ao envelhecimento populacional em todo o mundo, tem ocasionado modifica????es nos crit??rios de aceita????o dos ??rg??os pelas equipes transplantadoras. O presente trabalho buscou descrever o perfil epidemiol??gico, cl??nico e sorol??gico dos doadores de ??rg??os idosos com 60 anos ou mais, provenientes da Central Nacional de Transplante ??? CNT, Brasil: 2011 a 2014, a evolu????o do n??mero de doa????es de ??rg??os e o desfecho do processo de doa????o quanto ao aproveitamento dos ??rg??os de doadores idosos. Para tal, foi realizado um estudo descritivo, explorat??rio, retrospectivo, de s??rie temporal e documental, com dados secund??rios, abrangendo as Unidades da Federa????o (UF) do Brasil, para os anos de 2011 a 2014, provenientes dos processos de doa????o / distribui????o de ??rg??os s??lidos (cora????o, pulm??o, f??gado, rim e p??ncreas), realizados pelo CNT por doadores com 60 anos ou mais. Foram analisados 1.173 processos de doa????o nos quais, 38,6% dos doadores tinham entre 60 e 64 anos, e 31,5%, entre 65 e 69 anos. Quanto ao sexo, 57,9% dos doadores eram homens e o AVC ??? H foi a principal causa de morte. Em rela????o ??s disponibiliza????es de ??rg??os pelas Unidades Federativas para distribui????o nacional, Santa Catarina (20,2%), Cear?? (13%) e Rio de Janeiro (11,3%) foram as que mais ofertaram. Os principais ??rg??os ofertados foram: rim, f??gado, cora????o e pulm??o, nesta ordem. Quanto ao tempo de interna????o do potencial doador, a m??dia de interna????o foi de 5 a 6 dias. E quanto ao uso de droga vasoativa e antibi??tico n??o foi significativa a diferen??a entre doadores com ??rg??os transplantados e doadores com ??rg??os descartados. No que tange ?? sorologia, a presen??a ou n??o das sorologias estudadas positivas n??o influenciou na aceita????o do ??rg??o, no entanto, as vari??veis creatinina, ureia e bilirrubina quando alteradas, representaram maior possibilidade de descarte desses ??rg??os. A partir desses resultados, sugere-se a realiza????o de mais pesquisas com o objetivo de conhecer o perfil do doador idoso de ??rg??os e, mediante isso, estimular o aproveitamento dos ??rg??os provenientes desses doadores pelas equipes transplantadoras e Centrais Estaduais de Transplantes.
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Alenad, Amal. "The role of DNA methyltransferases in fetal programming." Thesis, University of Southampton, 2011. https://eprints.soton.ac.uk/338966/.

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Human epidemiological and experimental animal studies show that a poor intra-uterine environment induced by restricted maternal diet during pregnancy leads to persistent alterations in the metabolism and physiology of the offspring and an altered susceptibility to chronic disease in adult life such as cardiovascular disease and metabolic syndrome. This phenomenon has been termed fetal programming. In rats, maternal protein restriction (MPR) during pregnancy alters the expression of specific genes involved in lipid and carbohydrate homeostasis such as glucocorticoid receptor (GR) and peroxisomal proliferator-activated receptor–alpha (PPARα). Evidence is accumulating which indicates that persistent changes in the expression of GR and PPARα are mediated by changes in the epigenetic regulation of these genes within the offspring. Epigenetics refers to processes that stably alter gene activity without altering DNA sequence. DNA methylation and histone modification are the most significant epigenetic modifications. However the mechanism by which alterations in maternal diet can induce the altered epigenetic regulation of genes such as GR or PPARα is currently unknown. The aim therefore of this project was to investigate the role of the DNA methyltransferase1 (Dnmt1). Dnmt1 is essential for the maintenance of DNA methylation patterns in the induction of the altered epigenetic regulation of genes in response to maternal diet. We initially investigated the effect of MPR on Dnmt1 mRNA expression in heart, brain and spleen from control and protein restriction (PR) offspring on PN34. We found that MPR altered the expression of Dnmt1 and the de novo DNA methyltransferases Dnmt3a, and 3b in a tissue specific manner. The effect of MPR on the expression and methylation of GR and PPARα was also tissue specific. However, in most tissues examined there was not a simple inverse relationship between GR or PPARα expression and methylation or with levels of Dnmt1 expression. To assess how widespread the changes in gene expression induced by MPR are, microarray analysis was conducted in E8 embryos from control and PR fed dams and results were validated by RT-PCR. Results showed that only relatively small subsets of genes were affected by MPR or global dietary restriction (UN). Gene ontology analysis also revealed that similar pathways were altered under condition of both maternal PR and UN and interestingly one of the pathways altered by both maternal PR and UN was chromatin modification. In both PR and UN embryos on E8 a decrease in Dnmt1, Dnmt3a and 3b expression was observed as well as a decrease in the histone methyltransferases EZH2, Suv39H1 and the HDAC Sirt1 in the embryos from PR dams compared to controls. Alterations in the expression of the DNA and histone methyltransferases in response to MPR were accompanied by changes in DNA methylation and histone modification at the GR promoter as early as E14.
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Lago, Patr?cia Miranda do. "Interven??es m?dicas nas ?ltimas 48 horas de vida de pacientes internados em UTIP em tr?s regi?es do Brasil." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2007. http://tede2.pucrs.br/tede2/handle/tede/1453.

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Resumo de Limita??o no Suporte de vida Objetivo: Avaliar a incid?ncia de limita??o de suporte de vida (LSV) e as condutas m?dicas nas ?ltimas 48 horas de vida de crian?as internados em 7 UTIP de 3 regi?es brasileiras. Desenho: Estudo transversal, multic?ntrico e retrospectivo por revis?o de prontu?rio. Local (setting): 7 UTIP de hospitais universit?rios e terci?rios localizados em 3 regi?es Brasileiras, em Porto Alegre (2), S?o Paulo (2) e Salvador(3) Pacientes: todos pacientes que faleceram nas 7 UTIP no per?odo entre Janeiro de 2003 e dezembro de 2004. M?todos e principais resultados: Dois residentes de cada servi?o preencheram um protocolo padr?o com dados demogr?ficos, classificando o ?bito (reanima??o completa, ordem de n?o reanimar ou retirada de tratamento) e as condutas tomadas nas ?ltimas 48 horas de vida. Os dados foram comparados utilizando teste t de Student, Anova, Qui quadrado e RR. Dos 561 ?bitos, foram exclu?dos 36 com menos de 24 horas de interna??o, 61 com morte encef?lica e 36 prontu?rios n?o localizados. Em 56,5% dos ?bitos foram oferecidas manobras de ressuscita??o cardiopulmonar, com diferen?a entre regi?o sudeste e nordeste (p<0,001). A maior faixa et?ria (p=0,025) e maior tempo de interna??o na UTIP (p=0,001) foram fatores associados a n?o reanima??o. Em apenas 52,7% dos pacientes com LSV houve descri??o de plano no prontu?rio. O ?bito sem suporte respirat?rio ocorreu em apenas 14 pacientes. Em 66,1% pacientes com ordem de n?o reanimar as drogas inotr?picas foram mantidas ou aumentadas. Conclus?o: A incid?ncia de LSV tem aumentado nas UTIP brasileiras, havendo diferen?as entre regi?es. A ordem de n?o reanima??o ainda ? a pratica mais em nosso meio, havendo t?midas iniciativas de retirada de suporte. Resumo de Morte encef?lica Objetivo: Avaliar a incid?ncia de Morte Encef?lica (ME) bem como as condutas e protocolos adotados ap?s esta confirma??o diagn?stica em 7 UTIP localizadas em 3 regi?es Brasileiras. M?todo: Estudo transversal e multic?ntrico baseado na revis?o e an?lise retrospectiva de prontu?rios de todos os ?bitos ocorridos entre janeiro de 2003 e dezembro de 2004 em 7 UTIP localizadas em Porto Alegre (2), S?o Paulo (2) e Salvador (3). Dois residentes de cada servi?o previamente treinados preencheram protocolo padronizado avaliando dados demogr?ficos, a causa do ?bito, crit?rios para diagnostico de ME e a conduta m?dica adotada. Resultados: Identificamos 525 ?bitos, sendo 61 (11,6%) com diagn?stico de ME. A incid?ncia de ME diferiu entre as 7 UTIP (24,2% a 4,5%; p=0,015), por?m, sem diferen?a nas 3 regi?es (12% x 15% x 7%; p=0,052). A causa mais freq?ente foi Hemorragia Intracraniana (31,1%). Em 80% dos casos o diagnostico clinico de ME foi confirmado por exame complementar (100% na regi?o sul, 68% na sudeste e 72% na nordeste, p=0,02). A retirada de suporte vital ap?s diagnostico de ME diferiu nas 3 regi?es, sendo mais r?pida (p=0,04) no sul (1,8 ?1,9 hs) que no Sudeste (28,6 ?43,2hs) e Nordeste (15,5 ?17,1hs). Apenas 6 (9,8%) crian?as com ME foram doadoras de ?rg?os. Conclus?o: Apesar da lei que define crit?rios para Morte Encef?lica existir no Brasil desde 1997, verificamos que ela n?o ? obedecida uniformemente. Consequentemente, suporte vital desnecess?rio ? ofertado a indiv?duos j? mortos, existindo ainda um modesto envolvimento das UTIP com doa??es de ?rg?os
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Spikings, Emma Catherine. "Mitochondrial DNA replication in pre-implantation embryonic development." Thesis, University of Birmingham, 2007. http://etheses.bham.ac.uk//id/eprint/45/.

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All eukaryotic cells possess mitochondrial DNA (mtDNA), which is maternally inherited through the oocyte, its replication being regulated by nuclear-encoded replication factors. It was hypothesised that mtDNA replication is highly regulated in oocytes, pre-implantation embryos and embryonic stem cells (ESCs) and that this may be disrupted following nuclear transfer (NT). MtDNA copy number decreased between 2-cell and 8-cell staged porcine embryos and increased between the morula and expanded blastocyst stages, coinciding with increased expression of mtDNA replication factors. Competent porcine oocytes replicated their mtDNA prior to and during in vitro maturation to produce and maintain the 100000 mtDNA copies required for fertilisation. Those oocytes in which mtDNA replication was delayed had reduced developmental ability. Expression of pluripotency-associated genes decreased as murine ESCs differentiated into embryoid bodies, although expression of mtDNA replication factors did not increase until the stage equivalent to organogenesis. Cross-species NT embryos in which the donor cell-derived mtDNA was replicated produced decreased developmental outcomes compared to those in which no mtDNA replication took place. Disruption of the strict regulation of mtDNA replication that occurs during early embryogenesis, as is likely following NT, may therefore contribute to the reduced developmental ability of embryos produced using such techniques.
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Tang, Honghao. "DOA estimation based on MUSIC algorithm." Thesis, Linnéuniversitetet, Institutionen för fysik och elektroteknik (IFE), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-35058.

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Array signal processing is an important branch in the field of signal processing. In recent years, it has developed dramatically. It can be applied in such fields as radio detection and ranging, communication, sonar, earthquake, exploration, astronomy and biomedicine. The field of direction of array signal processing can be classified into self-adaption array signal processing and spatial spectrum, in which spatial spectrum estimation theory and technology is still in the ascendant status, and become a main aspect in the course of array signal processing. Spatial spectrum estimation is focused on investigating the system of spatial multiple sensor arrays, with the main purpose of estimating the signal’s spatial parameters and the location of the signal source. The spatial spectrum expresses signal distribution in the space from all directions to the receiver. Hence, if one can get the signal’s spatial spectrum, then the direction of arrival (DOA) can be obtained. As thus, spatial spectrum estimation is also called DOA estimation. DOA technology research is important in array signal processing, which is an interdisciplinary technology that develops rapidly in recent years, especially the direction of arrival with multiple signal sources, the estimation of coherent signal sources, and the DOA estimation of broadband signals. DOA estimation has a wide application prospect in radar, sonar, communication, seismology measurement and biomedicine. Over the past few years, all kinds of algorithms which can be used in DOA estimation have made great achievements, the most classic algorithm among which is Multiple Signal Classification (MUSIC). In this thesis I will give an overview of the DOA estimation based on MUSIC algorithm.
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9

YAN, HUIQIN. "CYCLOSTATIONARITY BASED DOA ESTIMATION AND TRACKING." University of Cincinnati / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1130250195.

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10

Tiedt, Caio Luiz. "RG flows e sistemas dinâmicos." Universidade de São Paulo, 2019. http://www.teses.usp.br/teses/disponiveis/43/43134/tde-18032019-151627/.

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No contexto de Renormalização Wilsoniana, os fluxos do grupo de renormalização (RG flows) são um conjunto de equações diferenciais que define como as constantes de acoplamento de uma teoria dependem de uma escala de energia. o conteúdo destes é semelhante a como sistemas termodinâmicos estão relacionados com a temperatura. Neste sentindo, é natural olhar para estruturas nos fluxos que demonstram um comportamento termodinâmico. A teoria matemática para estudar estas equações é chamada de sistemas dinâmicos e aplicações desta têm sido usadas no estudo de RG flows. Como exemplo o teorema-C de Zamolodchikov e os equivalentes teoremas em dimensões maiores mostram que existe uma função monotonicamente decrescente ao longo do fluxo e é uma propriedade que se assemelha à segunda lei da termodinâmica, estão relacionadas com a função de Lyapunov no contexto de sistemas dinâmicos e podem ser usadas para excluir a possibilidade de comportamentos assintóticos exóticos, como fluxos periódicos ou ciclos limites. Estudamos a teoria de bifurcação e a teoria de índice, que foram propostas como sendo úteis no estudo de RG flows: a primeira pode ser usada para explicar constantes cruzando pela marginalidade e a segunda para extrair informação global do espaço em que os fluxos vivem. Nesta dissertação, também olhamos para aplicações em RG flows holográficos e tentamos buscar relações entre as estruturas em teorias holográficas e as suas duais teorias de campos.
In the context of Wilsonian Renormalization, renormalization group (RG) flows are a set of differential equations that defines how the coupling constants of a theory depend on an energy scale. These equations closely resemble thermodynamical equations and how thermodynamical systems are related to temperature. In this sense, it is natural to look for structures in the flows that show a thermodynamics-like behaviour. The mathematical theory to study these equations is called Dynamical Systems, and applications of that have been used to study RG flows. For example, the classical Zamolodchikov\'s C-Theorem and its higher-dimensional counterparts, that show that there is a monotonically decreasing function along the flow and it is a property that resembles the second-law of thermodynamics, is related to the Lyapunov function in the context of Dynamical Systems. It can be used to rule out exotic asymptotic behaviours like periodic flows (also known as limit cycles). We also study bifurcation theory and index theories, which have been proposed to be useful in the study of RG flows, the former can be used to explain couplings crossing through marginality and the latter to extract global information about the space the flows lives in. In this dissertation, we also look for applications in holographic RG flows and we try to see if the structural behaviours in holographic theories are the same as the ones in the dual field theory side.
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Silva, Ana Alexandra Lázaro Vieira da. "Estatuto sintáctico doa "advérbios": função e classe." Doctoral thesis, Universidade de Évora, 2008. http://hdl.handle.net/10174/11130.

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A linguagem verbal, meio privilegiado de comunicação do ser humano, faz uso da sua capacidade de representação simbólica e é um meio e um fim das nossas experiências do dia a dia. O estudo da função do advérbio e a sua identidade enquanto classe, deverá ser enquadrada no âmbito da sintaxe frásica, visto que se trata de um fenómeno apenas observável num contexto linguístico. Não constitui nosso objectivo estudar a unidade lexical isolada, nem proceder prioritariamente ao levantamento das suas características morfológicas, mas verificar qual o comportamento que adopta no contexto em que se insere, esperando que daí resultem informações para a sua identificação enquanto classe. Com a análise do funcionamento dos advérbios pretendemos, em primeiro lugar, reflectir sobre algumas das propostas apresentadas por diversos gramáticos e linguistas para identificação das estruturas que incluem o advérbio na sua formação e que podem assumir em relação ao verbo não só funções / estatutos sintácticos próprios de um circunstante, como também de um argumento. O emprego de critérios de ordem sintáctica regeu o nosso estudo do comportamento dos advérbios em função circunstancial com estatuto sintáctico de argumento e o dos advérbios em função circunstancial com estatuto sintáctico de circunstante. Colateralmente, procuraremos definir esta função que é própria do advérbio e classificá-la, de acordo com critérios de ordem funcional. /ABSTRACT - The verbal language, privileged means of human being communication, makes use of its capacity of symbolic representation and it is a means and an end of our experiences of the daily life. The study of the adverbs' function and its identity as a class, should be framed within phrasal syntax, for it is a phenomenum only observable inside a linguistic context. It is not our aim to study the isolated lexical unit, nor to investigate its morphological characteristics, but, to verify its behaviour within a syntactical context. Thus, we aim to obtain enough information to identity an adverb as a paradigme. We first intended to analyse adverbs, by reflecting on some of the proposals presented by several grammarians and linguists. Then, adopting syntactic criteria we will determine the relation which an adverb assumes with the verb. An adverb can assume an argument status, or a circunstancial status, according with the relation it maintains with the verb, the nucleous of the phrase. We will also, determine how an adverb can be identified as a full member of a class, through the use of syntactical criteria.
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Stefer, Markus [Verfasser]. "DoA Estimation With Reduced Hardware Complexity / Markus Stefer." München : Verlag Dr. Hut, 2016. http://d-nb.info/1100969071/34.

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Panáček, Jiří. "Vytvoření DOA organizace v prostřední VUT v Brně." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2018. http://www.nusl.cz/ntk/nusl-377471.

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This diploma thesis deals with DOA organization in the environment of Brno University of Technology. Its aim is a research of regulatory requirements for the DOA; to propose a procedure for obtaining Design Organization Approval and a summary of information about necessary staffing.
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Kocaoglu, Argun H. "Rg wave dispersion tomography in northern Alabama." Thesis, Georgia Institute of Technology, 1990. http://hdl.handle.net/1853/25765.

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15

Gear, Daniel E. "DOA estimation by eigendecomposition using single vector Lanczos Algorithm." Thesis, Monterey, California. Naval Postgraduate School, 1989. http://hdl.handle.net/10945/27000.

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16

Liu, Hui. "Performance analysis of DOA estimation algorithms using physical parameters." PDXScholar, 1992. https://pdxscholar.library.pdx.edu/open_access_etds/4362.

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Analytical performance analysis on Direction-Of-Arrival (DOA) estimation algorithms has attracted much excellent research in recent years, various statistical properties have been revealed. However, in most of these analyses, insights of the performance were masked because of the involvement of singular values and singular vectors which depend on the character of the algorithms and data structures in a complex and nonlinear manner.
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Lu, Yang. "Unified Bias Analysis of Subspace-Based DOA Estimation Algorithms." PDXScholar, 1993. https://pdxscholar.library.pdx.edu/open_access_etds/4613.

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This thesis presents the unified bias analysis of subspace-based DOA estimation algorithms in terms of physical parameters such as source separation, signal coherence, number of senors and snapshots. The analysis reveals the direct relationship between the performance of the DOA algorithms and signal measurement conditions. Insights into different algorithms are provided. Based upon previous first-order subspace perturbations, second-order subspace perturbations are developed which provide basis for bias analysis and unification. Simulations verifying the theoretical bias analysis are presented.
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Hyberg, Per. "Antenna array mapping for DOA estimation in radio signal reconnaissance." Doctoral thesis, Stockholm, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-130.

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Pan, Yaobin. "Impact of DOA (direction of arrival) : in 4G MIMO Systems." Thesis, Linnéuniversitetet, Institutionen för fysik och elektroteknik (IFE), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-42158.

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Gomes, Marco Aurelio Cazarotto 1984. "Filtragem otima para melhorar o desempenho de estimadores DOA-ML." [s.n.], 2009. http://repositorio.unicamp.br/jspui/handle/REPOSIP/261946.

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Orientador: Amauri Lopes
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Eletrica e de Computação
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Resumo: Abordamos o problema de estimação de direção de chegada (DOA) de ondas planas usando um arranjo de sensores. Na literatura encontramos diversos estimadores para DOA, porém estamos considerando apenas os estimadores de Máxima Verossimilhança (ML) que geram candidatas à estimativa DOA e selecionam as melhores através do critério ML. Também estamos interessados em situações em que o espaçamento angular entre as fontes de sinal é pequeno e a relação sinal-ruído é baixa. Nesse caso temos uma degradação de desempenho associada ao efeito de limiar. Mostramos que este problema pode ser amenizado reduzindo o ruído presente na matriz de covariância dos dados recebidos (snapshots) utilizada para a seleção das candidatas. Propomos então modificar o processo de seleção de candidatas, utilizando uma nova matriz de covariância dos snapshots, calculada após uma filtragem ótima dos dados através de um filtro FIR multibanda. Propomos também modificar a função custo ML para adequá-la às dimensões da matriz de covariância filtrada e para isso apresentamos 3 opções de modificação. As simulações mostram que nossa proposta tem melhor desempenho que os métodos conhecidos, reduzindo significativamente a relação sinal-ruído de limiar.
Abstract: We approached the estimation of direction of arrival (DOA) of plane waves using an array of sensors. In the literature there are several DOA estimators, but we considered only the maximum likelihood (ML) estimators that generate candidates for DOA estimation and select the best one through an ML criterion. We also considered situations where the signal sources are spatially closely spaced and the signal-to-noise ratio is low. In these cases a performance degradation associated with the threshold effect occur. We demonstrated that we can improve the estimation performance by reducing the noise in the received data covariance matrix used to select the candidates. Then we proposed to modify the selection process using a new data covariance matrix, computed after an optimum multiband FIR filtering of the received data. We also proposed to modify the ML cost function to adapt it to the dimensions of the new covariance matrix and we considered 3 alternatives of modification. Some simulations showed that our proposal has better performance than known DOA methods, significantly reducing the threshold SNR.
Mestrado
Telecomunicações e Telemática
Mestre em Engenharia Elétrica
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21

Hayhurst, Kyle. "DOA Estimation of Ground Based Signals Using Airborne SATCOM Antennas." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1284566671.

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22

Ugolotti, Alessandro. "Alternative derivative expansion in Functional RG and application." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2016. http://amslaurea.unibo.it/10434/.

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We give a brief review of the Functional Renormalization method in quantum field theory, which is intrinsically non perturbative, in terms of both the Polchinski equation for the Wilsonian action and the Wetterich equation for the generator of the proper verteces. For the latter case we show a simple application for a theory with one real scalar field within the LPA and LPA' approximations. For the first case, instead, we give a covariant "Hamiltonian" version of the Polchinski equation which consists in doing a Legendre transform of the flow for the corresponding effective Lagrangian replacing arbitrary high order derivative of fields with momenta fields. This approach is suitable for studying new truncations in the derivative expansion. We apply this formulation for a theory with one real scalar field and, as a novel result, derive the flow equations for a theory with N real scalar fields with the O(N) internal symmetry. Within this new approach we analyze numerically the scaling solutions for N=1 in d=3 (critical Ising model), at the leading order in the derivative expansion with an infinite number of couplings, encoded in two functions V(phi) and Z(phi), obtaining an estimate for the quantum anomalous dimension with a 10% accuracy (confronting with Monte Carlo results).
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Colares, Ricardo Fialho. "Descrição unificada de metodos de estimação DOA em arranjo de sensores." [s.n.], 2000. http://repositorio.unicamp.br/jspui/handle/REPOSIP/260620.

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Orientador: Amauri Lopes
Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Eletrica e de Computação
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Resumo: Este trabalho aborda a aplicação de arranjo de sensores no problema de estimação do ângulo-de-chegada (DOA) de ondas planas. Uma vasta gama de aplicações nas mais diversas áreas se enquadram nesse problema, como em radar, sonar e mais recentemente em comunicações móveis. Dentre os métodos existentes para estimação de parâmetros, destacam-se os paramétricos em relação aos espectrais. Este trabalho classifica os principais métodos paramétricos em três categorias. A primeira consiste de métodos baseados no bastante conhecido critério da máxima-verossimilhança (ML), tais como o IQML e MO DE. A segunda categoria compreende os métodos baseados na predição linear, dentre os quais podemos citar o FBLP Modificado e o WTLS-LP. A terceira consiste nos métodos que fazem uso dos sub­espaços definidos pela matriz de correlação dos dados disponíveis, como os métodos MUSIC, NORMA-MÍNIMA, ESPRIT e WSF. Esses métodos são apresentados neste trabalho de uma forma unificada, na qual as estimativas desejadas são obtidas através da minimização de funções custo adequadas e com mesma estrutura. Nesse processo de otimização fazemos uso do critério dos mínimos-quadrados (LS) e dos mínimos-quadrados totais (TLS), além de suas variações que também são descritas. A visão unificada proposta aqui torna possível uma comparação de desempenho e esforço computacional entre esses métodos, evidenciando suas vantagens e desvantagens. Além disso, torna também possível a sugestão de propostas para novos métodos baseados naqueles existentes
Abstract: This work is concerned with the direction-of-arrival estimation of plane waves impinging on a sensors array. This problem arises from applications such as radar, sonar and, more recently, in wireless communications. Among the usual parameter estimation methods, the parametric ones are more accurate than the spectral ones. In this work the parametric methods are presented and classified in three categories. The first one consists of methods based on the well known maximum-likelihood (ML) criterion, such as the IQML and MO DE methods. The second class is composed of methods that use the linear prediction concepts, such as the Modified FBLP an the WTLS-LP. The last class is based on the subspace approach such as the MUSIC, MINIMUM-NORM, ESPRIT and WSF methods. Those methods are presented using an unifying formulation and notation, in which case the estimation is reached by minimizing suitable and similar cost functions. The minimization process is carried out by using the least­squares (LS) and total least-squares(TLS) approaches, as well as through variants that are also presented. This unifying framework make it possible to compare the performance and computational effort of the methods presented, showing the advantages and the disadvantages of each one. In addition, we propose new methods based on the existing ones
Doutorado
Doutor em Engenharia Elétrica
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24

Godinho, Sibele Grasiela Guedes. "D??diva e APP: doa????o na perspectiva de aplicativos sociais." Universidade Cat??lica de Bras??lia, 2016. https://bdtd.ucb.br:8443/jspui/handle/tede/2095.

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This research considers the potential motivations of using a social app for the realization of donations and probe the symbolic interactions that occur during solidarity exchanges mediated by technology. Smartphones and their applications are inseparable increasingly part of the daily lives of people who spend all their time with their devices: always on, always connected, as close as the shirt itself. Applications for mobile devices -apps- are the software installed in these smartphones that perform or assist in performing tasks for their users. Among the tools that the various types of apps present, there is a category of social apps, which are those facing a social cause. The conducted study noted when addressing the social application Solidarius, created for realization of donations to the group of welfare Sociedade S??o Vicente de Paulo, Vicentinos, which by enabling the realization of solidarity mediated by technology, materializes a new type of solidarity , anonymous, but allows the existence of a link, which excludes the direct involvement with people in common vulnerability in voluntary actions, but allows the user a sense of belonging, even if momentarily, to a larger institution or cause himself, and generate feelings of satisfaction and gratitude. These observations were made possible by the bibliography study published on the subject, the data analysis and information gathered during interviews with the developers of social application on screen and representatives of the institution that it will use, and the above discussion in focus group held with potential users of the application. As a result, to be detailed in subsequent research, it was realized that social applications allow its users an empowerment, regarding the perception that are interfering with reality and contributing to a cause, and that the technology of apps, for convenience, ease and closeness they have with the user, can be instruments of social change.
Esta pesquisa considera as potenciais motiva????es do uso de um aplicativo -app social para a realiza????o de doa????es e sonda as intera????es simb??licas que ocorrem durante as trocas solid??rias mediadas pela tecnologia. Os smartphones e seus indissoci??veis aplicativos fazem cada vez mais parte do cotidiano das pessoas, que passam todo o tempo com seus aparelhos: sempre ligados, sempre conectados, t??o pr??ximos como a pr??pria roupa do corpo. Os aplicativos para dispositivos m??veis -apps- s??o os softwares instalados nestes smartphones que realizam ou auxiliam a realiza????o de tarefas pelos seus usu??rios. Entre as ferramentas que os v??rios tipos de apps apresentam, existe a categoria de apps sociais, que s??o aqueles voltados para uma causa social. O estudo conduzido observou, ao abordar o aplicativo social SOLID??RIUS, criado para realiza????o de doa????es para o grupo de assist??ncia social Sociedade S??o Vicente de Paulo- Vicentinos, que ao possibilitar a realiza????o da solidariedade mediada pela tecnologia, materializa-se um novo tipo de solidariedade, an??nima, mas que possibilita a exist??ncia de um v??nculo, que exclui o envolvimento direto com as pessoas em situa????o de vulnerabilidade comum nas a????es de voluntariado, mas permite ao usu??rio um sentido de pertencimento, ainda que moment??neo, a uma institui????o ou causa maior que ele mesmo, al??m de gerar os sentimentos de satisfa????o e gratid??o. Estas observa????es foram possibilitadas pelo estudo de material bibliogr??fico publicado sobre o assunto, pela an??lise de dados e informa????es colhidas durante a realiza????o de entrevistas com os desenvolvedores do aplicativo social em tela e representantes da institui????o que dele far?? uso e pelo debate exposto em grupo focal realizado com potenciais usu??rios do aplicativo. Como resultados, a serem aprofundados em pesquisas posteriores, foi percebido que os aplicativos sociais permitem aos seus usu??rios um empoderamento, no tocante ?? percep????o que est??o interferindo na realidade e contribuindo com uma causa, e, que a tecnologia dos apps, pela praticidade, facilidade e proximidade que possuem com o usu??rio, podem ser instrumentos de transforma????es sociais.
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25

Shkotova, Viktoriia. "Návrh systému sběru a vyhodnocovaní událostí v provozu u DOA organizace." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2021. http://www.nusl.cz/ntk/nusl-449716.

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The diploma thesis focuses on the issue of the system of collection and evaluation of operational events at the DOA organization. It specifies the basic legislative requirements and regulations in the field of reporting incidents of an aircraft technical. For the analysis of the given topic, Czech companies were contacted, which could share their own experience in the framework of security management using a proactive method. Based on the summary of findings, the system of event collection and processing was designed. The system could be used by organizations dealing with the design of aircraft category ELA2
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Pangon, Vincent. "An RG study of models with spontaneous symmetry breaking." Strasbourg, 2009. http://www.theses.fr/2009STRA6116.

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Aatique, Muhammad. "Evaluation of TDOA Techniques for Position Location in CDMA Systems." Thesis, Virginia Tech, 1997. http://hdl.handle.net/10919/9558.

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The Federal Communications Commission (FCC) has adopted regulations requiring wireless communication service providers to provide position location (PL) information for a user requesting E-911 service. The Time Difference of Arrival (TDOA) technique is one of the most promising position location techniques for cellular-type wireless communication systems. The IS-95 Code Division Multiple Access (CDMA) system is a popular choice for the companies deploying new cellular and PCS systems in North America. Hence, the feasibility of TDOA techniques in CDMA systems is an important issue for position location in the wireless systems of the future. This thesis analyzes the performance of TDOA techniques in the CDMA systems. A comparison and assessment of different algorithms for finding the time difference estimates and for solving the hyperbolic equations generated by those estimates has been made. This research also considers a measure of accuracy for TDOA position location method which is shown to be more suitable for CDMA systems and more closely matches to the FCC requirements. Among the other contributions is a proposed method to perform cross-correlations to identify only the desired user's TDOA in a multiuser environment. This thesis also evaluates the feasibility and accuracy of TDOA techniques under varying system conditions that might be encountered in real situations. This includes varying conditions of Additive White Gaussian Noise (AWGN), Multiple Access Interference (MAI), power control and loading. The effect of the mobile position and of different arrangement of base stations on TDOA accuracy is also studied. Performance comparison in AWGN and Rayleigh fading channels is made. The feasibility of using increased power levels for the 911 user in combination with interference cancellation is also studied. The effect of using a single stage of parallel interference cancellation at neighboring cell sites has also been explored. Non-ideal situations such as imperfect power control in CDMA operation has also been investigated in the context of position location. This thesis also suggests amethod to correct TDOA estimation errors in CDMA. It is shown that this improvement can give greatly improved performance even under worst-case situations. Performance comparison of results with and without that modification has also been made under various conditions.
Master of Science
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28

ZHOU, XIN. "SPATIO-TEMPORAL JOINT MUSIC ALGORITHM FOR NARROWBAND AND WIDEBAND DIRECTION OF ARRIVAL ESTIMATION." University of Cincinnati / OhioLINK, 2003. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1069850811.

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Yasar, Temel Kaya. "Improvements In Doa Estimation By Array Interpolation In Non-uniform Linear Arrays." Master's thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/12607524/index.pdf.

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In this thesis a new approach is proposed for non-uniform linear arrays (NLA) which employs conventional subspace methods to improve the direction of arrival (DOA) estimation performance. Uniform linear arrays (ULA) are composed of evenly spaced sensor elements located on a straight line. ULA'
s covariance matrix have a Vandermonde matrix structure, which is required by fast subspace DOA estimation algorithms. NLA differ from ULA only by some missing sensor elements. These missing elements cause some gaps in covariance matrix and Vandermonde structure is lost. Therefore fast subspace DOA algorithms can not be applied in this case. Linear programming methods and array interpolation methods can be used to solve this problem. However linear programming is computationally expensive and array interpolation is angular sector dependent and requires the same number of sensor in the virtual array. In this thesis, a covariance matrix augmentation method is developed by using the array interpolation technique and initial DOA estimates. An initial DOA estimate is obtained by Toeplitz completion of the covariance matrix. This initial DOA estimates eliminates the sector dependency and reduces the least square mapping error of array interpolation. A Wiener formulation is developed which allows more sensors in the virtual array than the real array. In addition, it leads to better estimates at low SNR. The new covariance matrix is used in the root-MUSIC algorithm to obtain a better DOA estimate. Several computer simulations are done and it is shown that the proposed approach improves the DOA estimation accuracy significantly compared to the same number of sensor ULA. This approach also increases the number of sources that can be identifed.
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Linddahl, Iréne. "Validity and Reliability of the Instrument DOA : A Dialogue about Working Ability." Licentiate thesis, Jönköping University, HHJ, Dep. of Rehabilitation, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-783.

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The overall aim of this thesis was to examine the construct validity and the reliability of the instrument DOA; Dialogue about working ability. The theoretical foundation for DOA is the Model of Human Occupation. The instrument is divided into two sections; client self-assessment and professional assessment focusing on the individual’s working ability. The assessments are followed by a dialogue to distinguish goals for the return to-work process based on the client’s own preferences. In line with the theoretical base, the concept ‘work’ refers to both paid work and other productive activities related to work.

In Study I, 21 professionals and 126 clients participated from three clinics in Sweden. All clients were involved as outpatients in psychiatric work rehabilitation in county councils or community services. The results from the Rasch analysis test indicated that items are well separated from each other and generally work together in five unidimensional continuums with the objective to measure abilities related to work. Twenty-nine of 34 items showed goodness-of-fit statistics, which means acceptable infit MnSq values from >0.6 to <1.4 in association with Z values from –2 to 2, and that the five misfit items have to be revised.

Thirty-four outpatient clients and 14 professionals from four clinics within psychiatric work rehabilitation in Sweden participated in Study II. Two reliability aspects were studied: test-retest and inter rater reliability. The statistical analyses used were Spearman Rank Correlation test and Percentage of agreement (PA). Generally, the Spearman Rank Correlation test showed acceptable significant correlations between test retest since a greater part of items correlated “moderate to good” (r = 0.51 – 0.75). In the inter raters´ test PA was good, ranging from 93.1 % to 96.5 %, which is well above the acceptable criteria of 80 %. There were no significance differences between the raters. The study has shown that one item has to revised.

The findings verify that DOA has potential as a means of making valid and reliable assessments of working ability, as described by the Model of Human Occupation, out of both clients´ and occupational therapists´ perspective.

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31

Linddahl, Iréne. "Validity and reliability of the instrument DOA; a dialogue about working ability /." Jönköping : Hälsohögskolan, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-783.

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32

Patriksson, Alfred. "Radio signal DOA estimation : Implementing radar signal direction estimation on an FPGA." Thesis, Linköpings universitet, Datorteknik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-157144.

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This master’s thesis covers the design and implementation of a monopulse directionof arrival (DOA) estimation algorithm on an FPGA. The goal is to implement a complete system that is capable of estimating the bearing of an incident signal. In order to determine the estimate quality both a theoretical and practical noise analysis of the signal chain is performed. Special focus is placed on the statistical properties of the transformation from I/Q-demodulated signals with correlated noise to a polar representation. The pros and cons for three different methods of calculating received signal phasors are also covered.The system is limited to two receiving channels which constrains this report to a 2D analysis. In addition the used hardware is limited to C-band signals. We show that an FPGA implementation of monopulse techniques is definitely viable and that an SNR higher than ten dB allows for a gaussian approximation of the polar representationof an I/Q signal.
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Andrade, Rita Morais de. "Boué Soeurs RG 7091: a biografia cultural de um vestido." Pontifícia Universidade Católica de São Paulo, 2008. https://tede2.pucsp.br/handle/handle/13076.

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Universidade Anhembi Morumbi
This theses investigates the social and cultural circulation of a frock from its manufacture in a couture House atelier back in the 1920s Paris to its storage at Museu Paulista da Universidade de São Paulo in 1993, where it was catalogued as Boué Soeurs RG 7091. Searching trhough some of this object paths its manufacturing, the people who wore it, the cities where it circulated this paper proposes the interpretation of objetcs as a method to elaborate a dress cultural biography. The material analyses of RG 7091, approached here as a historical document, allowed to question the idea of a totalitarian fashion hegemony over all forms of dress. Through the interpretation of certain material aspects, elements and articulation of the dress, I discuss some timely and spacially perceptions as well as youthness and modesty. The material evidences of people s interference but also of time, climate, storage and circulation conditions over textiled clothes indicate sensitive meanings in the ways to dress the body
Esta tese investiga a circulação social e cultural de um vestido desde sua confecção num atelier de alta-costura em Paris na década de 1920 até seu armazenamento na reserva técnica do Museu Paulista da Universidade de São Paulo em 1993, quando ele foi catalogado como Boué Soeurs RG 7091. Percorrendo algumas trajetórias deste objeto sua confecção, os corpos que vestiu, as cidades por onde passou , esta pesquisa propõe um método interpretativo de objetos como método para a elaboração de uma biografia cultural do vestido. A análise material do RG 7091, tratado aqui como um documento histórico, permitiu colocar em xeque a idéia de hegemonia da moda sobre todas as formas de vestir. Através da interpretação de determinadas marcas, elementos e articulações do vestido, discutem-se aqui percepções de temporalidades e espacialidades, juventude e pudor. As evidências materiais das interferências dos sujeitos e outros atores (tempo, clima, condições de armazenagem) sobre as roupas feitas de tecido indicam formas sensíveis de vestir os corpos
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34

Hu, Zhong. "Evaluation of Joint AOA and DOA Estimation Algorithms Using the Antenna Array Systems." Thesis, Virginia Tech, 1999. http://hdl.handle.net/10919/32015.

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We have created an eight-element antenna array system for evaluating various Angle of Arrival (AOA) Position Location (PL) algorithms, such as MUltiple SIgnal Classification (MUSIC) and Estimation of Signal Parameters via Rotational Invariance Techniques ESPRIT algorithms. Since using delay of arrival information can improve AOA estimates and classical PL algorithms do not incorporate Delay of Arrival (DOA) information, the performance of these algorithms is not optimal. Recently proposed Joint AOA and DOA Estimation (JADE) algorithms, though more complicated, potentially have higher resolutions in both space and time domains. Our investigation shows that by using bandlimited known signals it is possible to resolve the DOA within a fraction of the sample period using JADE algorithms. Joint AOA and DOA algorithms can provide high resolution DSP-based channel measurement using low bandwidth hardware.
Master of Science
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35

Kpebe, Arlette. "Structure, expression et fonctions des isoformes de la kinase LAMMER DOA de drosophile." Paris 11, 2007. http://www.theses.fr/2007PA112163.

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Le locus Darkener of apricot (Doa) code pour le seul homologue des kinases LAMMER chez la Drosophile. Les kinases LAMMER sont impliquées dans de nombreux processus biologiques. Le rôle le mieux connu est la régulation de l’épissage alternatif par phosphorylation directe des protéines SR. Par exemple, Doa phosphoryle les facteurs d’épissage TRA, TRA2 et RBP1 qui régulent l’épissage alternatif de gènes impliqués dans la voie de détermination sexuelle des tissus somatiques. Nous avons identifié 6 isoformes de la protéine DOA. Elles possèdent un domaine catalytique quasiment identique et des domaines N-terminaux non-catalytiques différents, grâce à l’utilisation de promoteurs alternatifs. Une première analyse de l’expression spécifique des transcrits codant les isoformes a révélé un profil d’expression indépendant les uns des autres, et nous a conforté dans l’hypothèse de fonctions séparables pour les isoformes. Des analyses génétiques des mutants Doa et l’observation des phénotypes de surexpression des isoformes spécifiques a confirmé une fonction distincte pour au moins deux isoformes de la kinase. De plus, nous avons pu mettre en évidence un rôle spécifique pour une troisième isoforme de 69 kD dans la différentiation sexuelle. Celle-ci possède une expression restreinte aux corps des femelles et l’expression de ses transcrits est sous contrôle des gènes tra, tra2 et dsx dans la voie de détermination sexuelle somatique. Les données obtenues nous ont permis de montrer que l’isoforme DOA de 69 kD formerait avec tra, tra2 et dsx une boucle positive d’autorégulation qui permettrait de renforcer le sort femelle chez la Drosophile
[The Darkener of apricot (Doa) locus encodes the Drosophila member of the LAMMER protein kinase family. LAMMER kinases are implicated in various biological processes. Their principal known function is the regulation of alternative splicing via the direct phosphorylation of SR proteins. For example, DOA phosphorylates the SR and SR-“like” proteins RBP1, TRA and TRA2, which regulate alternative splicing in the somatic sex determination pathway in Drosophila. We have identified 6 DOA protein isoforms with nearly identical catalytic domains but different N-terminal non-catalytic domains which arise through alternative promoter usage. Expression analysis of transcripts encoding these Doa isoforms show independent patterns, supporting the hypothesis of different functions. Extensive complementation analysis of Doa mutants, plus analysis of P-element insertions permitting GAL4-directed expression of specific Doa isoforms, and interfering RNA expression of one isoform show that at least two of them perform different functions. Moreover, we identified a specific function for a third isoform of 69 kD in somatic sexual differentiation. This isoform possesses female body-specific expression, and its transcript is under control of the tra, tra2 and dsx loci in the somatic sex determination pathway. Our data thus show that the DOA 69 kD isoform forms a positive autoregulatory loop with the tra, tra2 and dsx, reinforcing the female fate in Drosophila. ]
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Al, irkhis Luay A. "Wideband DoA and Parameter Estimation of Chirp Sources using DCFT and Compressive Sensing." Wright State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=wright1547548984021509.

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37

Rosenthal, Axel. "Probleme im zivilprozessualen Revisionszulassungsrecht nach Inkrafttreten des ZPO-RG vom 01.01.2002 /." Berlin : Logos-Verl, 2007. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=015593003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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38

Özakin, Arkadas I. Wise Mark B. "RG-flows, AdS/CFT correspondence and stability of non-dilatonic branes /." Diss., Pasadena, Calif. : California Institute of Technology, 2004. http://resolver.caltech.edu/CaltechETD:etd-04272005-130936.

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39

Spaniol, Ednardo Paulo. "Um paralelo entre o eletromagnetismo e o equivalente teleparalelo da RG." reponame:Repositório Institucional da UnB, 2007. http://repositorio.unb.br/handle/10482/8520.

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Dissertação (mestrado)—Universidade de Brasília, Instituto de Física, 2007.
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A suposicão de que cargas e correntes de matéria poderiam gerar campos chamados, em analogia ao eletromagnetismo clássico, gravito-elétrico e gravito-magnético origina-se nos primórdios da Relatividade Geral (RG). Por outro lado, o Equivalente Teleparalelo da RG (ETRG), como teoria de gauge, parece-nos o cenário ideal para a definição destes campos que corresponderiam, exatamente como o eletromagnetismo, às componentes do tensor intensidade do campo de gauge. Esta é a proposta deste trabalho: investigar a natureza dos campos gravitacionais elétrico e magnético no contexto do ETRG, analisar as equações que conduzem suas dinâmicas e estudar o comportamento destes campos sob algumas aplicações específicas, tais como a geometria de Schwarzschild e a casca massiva girante. _________________________________________________________________________________ ABSTRACT
The assumption that matter charges and currents could generate fields, called by analogy to eletromagnetism, gravito-eletric and gravito-magnetic, comes from the origin of General Relativity (RG). Besides, the Equivalente Teleparallel of GR (ETGR), as a gauge theory, seems to be the ideal scenario to define these fields, based on the gauge field strength components. This is the purpose of this work: to investigate the nature of the gravitational electric and magnetic fields in the context of ETGR, to analyze the equations that lead its dynamics and to study the behavior of these fields under some specific applications, such as the Schwarzschild geometry and the rotating mass shell.
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40

Haenel, Claude. "Neutropenie cyclique et traitement par rg-csf : a propos d'une observation." Université Louis Pasteur (Strasbourg) (1971-2008), 1991. http://www.theses.fr/1991STR1M217.

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41

Ozdilek, Bagdeser A., Valery F. Thompson, Nasiha S. Ahmed, Connor I. White, Robert T. Batey, and Jacob C. Schwartz. "Intrinsically disordered RGG/RG domains mediate degenerate specificity in RNA binding." OXFORD UNIV PRESS, 2017. http://hdl.handle.net/10150/625471.

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RGG/RG domains are the second most common RNA binding domain in the human genome, yet their RNA-binding properties remain poorly understood. Here, we report a detailed analysis of the RNA binding characteristics of intrinsically disordered RGG/RG domains from Fused in Sarcoma (FUS), FMRP and hnRNPU. For FUS, previous studies defined RNA binding as mediated by its well-folded domains; however, we show that RGG/RG domains are the primary mediators of binding. RGG/RG domains coupled to adjacent folded domains can achieve affinities approaching that of full-length FUS. Analysis of RGG/RG domains from FUS, FMRP and hnRNPU against a spectrum of contrasting RNAs reveals that each display degenerate binding specificity, while still displaying different degrees of preference for RNA.
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42

Stelmach, Aleksandra. "Field-making and sense-making : foetal programming, risk and human reproduction." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/52697/.

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43

Sembi, Sukhdev. "Mums4Mums : structured telephone peer-support for women experiencing postnatal depression : a pilot RCT to test its clinical effectiveness." Thesis, University of Warwick, 2018. http://wrap.warwick.ac.uk/114368/.

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Background: Postnatal Depression (PND) is experienced by around 13% of women, who suffer a range of disabling symptoms that can have a negative effect on the mother and infant relationship, with significant consequences in terms of the child's later mental health. Research has shown that providing support to mothers experiencing PND can help reduce their depressive symptoms and improve their coping strategies. This study aimed to evaluate the impact of telephone peer-support for women experiencing PND. Methods/Design: A pilot RCT was conducted in which women who screened positive for postnatal depression using the Edinburgh Postnatal Depression Scale (EPDS > =10) were randomised to receive telephone-based support from peers who had recovered from PND, or standard care. Primary outcome measures included depressive symptomatology measured post-intervention and at six-months using the EPDS, and parent-infant interaction using the CARE-Index. Secondary outcome measures included anxiety and depression, dyadic adjustment, parenting stress, and self-efficacy. Maternal perceptions of the telephone peer-support were being assessed using semi-structured interviews. Quantitative and qualitative data was also collected from the peer-supporters to assess the impact on them of delivering the intervention. Results: Participants: twenty-eight participants were recruited to the study, and there was a fifty-percent dropout rate (intervention group n=6, control group n=8). While there were no differences in EPDS scores between the two groups at post-intervention, the intervention group continued to improve at six-month follow-up, whereas the control group showed signs of relapse. The intervention had no impact on mother-infant interaction. In-depth interview data show that women valued the support that was provided. Peer-Supporters: nineteen peer-supporters were recruited, of whom five left before supporting a participant, and eight left after supporting only one participant. The quantitative results showed a significant non-clinical increase in anxiety at post intervention. The qualitative results indicated that the peer-supporters found the majority of calls challenging, and that delivering the intervention had had a deleterious impact on some peer-supporters. Conclusion: While these findings suggest a positive impact of telephone-based peer-support, further research into ways of improving mother-infant interaction are urgently required. Research is also required into providing effective support for the peer supporters.
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Eapen, Abey. "Recombinant human granulocyte colony stimulating factor for unexplained recurrent miscarriage : a randomised placebo controlled multi-centre study." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8297/.

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Immune mediated mechanisms are thought to contribute to recurrent pregnancy losses. A number of treatment options with limited evidence are being used in clinical practice to treat women with recurrent miscarriages. The objectives of this thesis was a. To summarise the available evidence for granulocyte colony stimulating factor (G-CSF) in reproductive medicine. b. To perform a randomised controlled study (RCT) to evaluate the efficacy and safety of recombinant human granulocyte colony stimulating factor (rhG-CSF) in women with unexplained recurrent miscarriages. The main conclusions from this thesis are: a. The systematic narrative review found that available evidence is of poor quality, but suggestive of benefit with granulocyte colony stimulating factor in women with recurrent miscarriages. b. The RCT concluded that administration of rhG-CSF does not improve pregnancy outcomes among women with a history of unexplained recurrent miscarriages. RhG-CSF appears to be safe for both mothers and their offspring/s.
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Shehmar, Manjeet. "An evaluation of recovery after hysterectomy." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8259/.

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Differences in recovery from types of hysterectomy may be due to different advice, rather than different incisions alone. Aims: What are the beliefs and experiences of women who have a hysterectomy and the practices and beliefs of health care professionals? Explore the evidence for psychological preparation for surgery. Methods: .Retrospective structured questionnaires .Semi-structured interviews and validated quality of life questionnaires .Systematic review Results: No significant difference in return to work for type of employment and incapacity pay. Variation between the advice given for recovery by UK gynaecologists and nurses. Regardless of route of surgery, the expectations and fears of women are similar and rely on health care advice, with conflicting advice and varied recovery experiences. Women who had a vaginal hysterectomy had concerns around sitting, laparoscopic route had a lower length of stay and abdominal hysterectomy had higher anxiety scores (P 0.003). Mean quality of life scores by EQ5 were not different based on route of surgery (pre-surgery P 0.4446, 1 week P 0.447, 4 weeks P 0.876,12 weeks P 0.850). There was a reduced length of stay [P 0.03, 5.65 (-10 82 to -0.48)] and reduced trait anxiety intervention [P < 0.00001, mean difference 7.78 (7.19, 10.61)] for psychological interventions.
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46

Walker, S. "Competence and expertise in physiological breech birth." Thesis, City, University of London, 2017. http://openaccess.city.ac.uk/20269/.

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This doctoral thesis by prospective publication aims to provide pragmatic, evidence-based guidance for the development and evaluation of physiological breech skills and services within the context of contemporary maternity care. The research uses multiple methods to explore development of professional competence and expertise. While skill and experience are acknowledged in multiple national guidelines as important safety factors in vaginal breech birth, prior to this research no guidance existed about how skill and experience should be defined, developed and evaluated. The thesis begins with an integrative review of the efficacy of current breech training methods, highlighting a lack of evidence associating any training methods with improved outcomes for breech births. Following this are two papers reporting the results of a Delphi consensus technique study involving a panel of breech experienced obstetricians, midwives and service user representatives. The first outlines standards of competence, training components and volume of experience recommended to achieve competence and maintain proficiency in upright breech birth. The second outlines principles of practice for physiological breech birth, rooted in relationship and response, and divergent from medicalised practices based on prediction and control. Following this is a grounded theory paper exploring the deliberate acquisition of breech competence among midwives and obstetricians with moderate upright breech experience. The paper reports a theoretical model that can inform development of breech teams and training programmes. The final paper reports a mixed methods analysis of data from the Delphi and grounded theory studies concerning breech expertise. The results present a model of generative expertise, underpinned by affinity, flexibility and relationship, which may function to increase the availability and safety of vaginal breech birth. Each paper is followed by critical analysis and reflection. The thesis ends with a discussion of the implications for practice and research in light of the overall body of work.
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47

Brown, Catriona Elizabeth. "Assessment of cardiovascular risk in women with a history of pre-eclampsia." Thesis, University of Glasgow, 2018. http://theses.gla.ac.uk/9129/.

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Pre-eclampsia is an important and serious condition affecting 2-8% of pregnancies worldwide and carries with it significant associated risk of morbidity and mortality for both mother and child. It is characterised by new onset hypertension after the 20th week of gestation with accompanying proteinuria. Resolution of symptoms should occur following delivery. Several pathophysiological mechanisms are common to both pre-eclampsia and cardiovascular disease, and the link between pre-eclampsia and cardiovascular disease later in life has been established. While the underlying pathophysiological mechanisms of pre-eclampsia are complex, endothelial dysfunction is a key component. Increased arterial stiffness and hypertension have also been documented. Endothelial dysfunction has been shown to extend beyond childbirth, into the postpartum period. Studies evaluating endothelial dysfunction at even longer time-points following an affected pregnancy have produced conflicting results. Results from biomarker studies have supported the concept of endothelial dysfunction throughout pregnancy and the postpartum period, but as more time elapses between index pregnancy and biomarker sampling, these results also vary. Cardiac imaging and electrocardiographic studies have also contributed to knowledge about the normal physiology of pregnancy and changes which are associated with hypertensive disorders of pregnancy during pregnancy, the postpartum period and beyond. The main focus of this thesis was to investigate the possible mechanisms behind the link between pre-eclampsia and future cardiovascular disease. The aim was to investigate women who were free from cardiovascular disease for any evidence of subclinical vascular damage long-term following a pre-eclamptic pregnancy. Overall women recruited to this study would be older than women who participated in the majority of previously published studies on this theme. Before embarking on the investigation of subclinical vascular damage in women with a history of pre-eclampsia, a link was confirmed between a history of pre-eclampsia and cardiovascular disease up to 30 years from time of index pregnancy. This was accomplished using record-linkage in a large Scottish cohort; the Generation Scotland Family Health Study (GS:SFHS). Following on from this, ECGs available in women with and without a remote history of pre-eclampsia in the GS:SFHS cohort were assessed for any obvious differences. There was a more leftward shift in the QRS-axis in these women and a trend towards a longer corrected QT interval (QTc) which approached statistical significance, but after adjusting for other co-variates, pre-eclampsia did not independently predict QTc. Investigations for subclinical vascular damage were carried out by means of non-invasive vascular function studies in women recruited from three different cohorts (blood pressure clinics, GS:SFHS and the previous Proteomics in Pre-eclampsia (PIP) study of women during pregnancy). Time since index pregnancy varied between 1-30 years. Flow-mediated dilatation (FMD) was performed to assess for endothelial dysfunction, pulse wave analysis (PWA) and pulse wave velocity (PWV) assessed arterial stiffness, and carotid ultrasound was performed to establish whether there was any evidence of atherosclerosis. After adjusting for other co-variates, I was able to demonstrate the presence of endothelial dysfunction many years after pregnancy in women with a history of pre-eclampsia in comparison with those who experienced a normotensive pregnancy. There was also a significantly higher presence of carotid plaque in women with a history of pre-eclampsia. To investigate whether the findings from the vascular study translated to findings in biomarker studies of women with a history of pre-eclampsia in comparison with controls, samples from the vascular studies cohort and from the wider GS:SFHS cohort were used. Markers of inflammation, angiogenesis, cardiac damage and collagen turnover were studied. A significantly higher vascular endothelial growth factor (VEGF) was detected in women with a history of pre-eclampsia. Pre-eclampsia is associated with an increased risk of cardiovascular disease, and endothelial dysfunction is evident later on in life. Larger studies are required to further investigate the vascular and biomarker results, and studies including more thorough cardiac assessment (such as echocardiography) in this population should also be considered. The studies described found no evidence of one single component to explain the relationship between pre-eclampsia and cardiovascular disease later in life. This is not unexpected as pre-eclampsia is a complex condition with multiple contributing factors and it is likely that the increased cardiovascular risk later in life is likewise multifactorial in origin.
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48

Hsin-Jung, Chen, and 陳信榮. "Fast Algorithms for 2-D DOA and DOA-Delay Tracking." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/01823206012361191220.

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碩士
國立臺灣科技大學
電子工程系
93
In this thesis, we present a fast, yet accurate adaptive algorithm for tracking two-dimensional (2-D) directions of arrival (DOAs) using a uniform rectangular array. The new algorithm employs three one-dimensional (1-D) subspace tracking algorithms to determine the two DOA components iteratively in a coarse-fine manner based on a single row or column of data. Also, to enhance the estimation accuracy, two complementary orthogonal beamforming processes are invoked between the 1-D subspace tracking algorithms to partition the incoming signals into appropriate groups so that the DOAs can be well resolved even if they are very close. Since the new algorithm only involves the 1-D subspace-based algorithm in determining the DOAs, the overall computational complexity called for is substantially less than the direct 2-D extension of the existing subspace tracking algorithms, which requires an update higher-dimensional eigendecomposition or 2-D search. %computationally demanding 2-D search. Furthermore, with the tree-structured estimation scheme, the estimated 2-D DOA components are automatically paired without extra computational overhead. The similar technique is also employed for joint DOA-delay estimation in wireless communication systems. Using a temporal filtering process and a spatial beamforming process, the proposed tree-structured approach can resolve incoming rays even with very close DOAs or delays. In addition, the estimated DOAs and delays are also automatically paired. Furnished simulations show that the new algorithm can provide satisfactory tracking performance of either the 2-D DOA or DOA-delay estimates in various scenarios.
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49

Chen, You-Yu, and 陳宥諭. "DOA Estimation with Artificial Neural Network." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/2pxvzy.

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碩士
國立交通大學
電信工程研究所
107
A uniform linear array can receive multiple unequal power signals coming from different direction-of-arrival (DOA). This thesis considers DOA estimation with artificial neural network (NN). Conventional NN approaches are not effective for the unequal-power scenario. Also, the computational complexity is very high. Incorporating signal processing techniques, we propose two NNs to solve the problems. The first NN divides the estimation range into sectors, and consists of a spatial filter and a classifier. With a rotation operation, a spatial filter and a classifier can be used for all sectors, significantly reducing the training time and computational complexity. The second NN uses the same sector-based processing structure. However, the spatial filter is replaced with a power detector. With a frequency-domain nulling operation, only a power detector and a classifier are needed for all sectors. The computational complexity of the second NN can be further reduced. Simulation results show that the performance of the proposed NNs can outperform the well-known MUSIC algorithm under low SNR. Also, the computational complexity can also be lower than that of MUSIC.
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WANG, JEN-CHANG, and 王仁昌. "Using TOA and DOA for Subscriber Geolocation." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/15870918055622479830.

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碩士
國立臺灣大學
電信工程學研究所
90
In this thesis we develop subscriber geolocation techniques for future W-CDMA applications. These techniques can be realized by a single base station (BS) equipped with an antenna array. The BS receives uplink signals and from which to estimate the time of arrival (TOA) and direction of arrival (DOA) of the direct path connecting from the mobile station (MS) to the BS. The MS’s position is then determined by the estimated TOA and DOA. We have proposed two methods, the downward search method and the upward search method, to estimate the TOA of the direct path. We also have proposed a method which utilizes non-uniform spaced array to determine the DOA of the direct path. Benefit of this method is that we can use less antenna elements but still have better estimation performance than that of a uniform array with the same aperture size but more elements. We have used the COST 259 channel model to generate wideband channel signals and use them to test the estimation performance of our proposed method. To improve the accuracy of geolocation, we have proposed methods which utilize estimations from multiple snapshots to locate the MS. We found that the geolocation performance can be improved significantly. We have conducted experiments in several typical environments, including a picocell environment, an environment with signal penetrating through buildings, a macrocell outdoor environment and a cell covered by multiple base stations. Simulation and experimental results have verified the effectiveness of our proposed methods.
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