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Feuerbacher, Erica Nan Rosales-Ruiz Jesus. "Natural concepts in the domestic dog." [Denton, Tex.] : University of North Texas, 2009. http://digital.library.unt.edu/ark:/67531/metadc12123.
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Feuerbacher, Erica Nan. "Natural concepts in the domestic dog." Thesis, University of North Texas, 2009. https://digital.library.unt.edu/ark:/67531/metadc12123/.
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The current study investigated concept formation in domestic dogs, specifically that of a toy concept. The dog's differential responding (retrieval vs. non-retrieval) to two sets of stimuli suggested a toy concept. Differential responding occurred from the very first trial, indicating that the concept had been formed in the natural environment, not during the experiment. It was hypothesized that a common response may be responsible for the emergence of the class in the natural environment. The results demonstrated that it was possible to expand the class by adding previously non-retrieved objects to the toy class through a common response. It was also shown that the toy concept passed the more stringent criterion (transfer of function test) required validating it as a concept.
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Yeung, Chui Wa. "An investigation of the sentiments of having a dog : inspirations for the design of a toy dog /." access full-text access abstract and table of contents, 2005. http://libweb.cityu.edu.hk/cgi-bin/ezdb/thesis.pl?mphil-meem-b19887607a.pdf.
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Thesis (M.Phil.)--City University of Hong Kong, 2005.<br>"Submitted to Department of Manufacturing Engineering and Engineering Management in partial fulfillment of the requirements for the degree of Master of Philosophy" Includes bibliographical references (leaves 238-243)
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Westgarth, Carri. "Contact between dogs, and between dogs and people." Thesis, University of Liverpool, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490708.
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Dogs are popular pets in many countries. The interactions that occur between dogs, and between dogs and humans, are of interest to behavioural, welfare, psychological and social sciences. As dogs are a potential source of zoonotic infections to humans, such interactions may also impact on public health. Interactions between dogs, for example whilst walking, may also transfer infectious diseases (zoonotic or non-zoonotic) through the pet dog population. Despite their popularity as pets, there have been no in-depth studies into the contacts that occur between dogs, and between dogs and people; this thesis uses a variety of methodologies to examine these contacts. A census-based, epidemiological study was used to investigate factors associated with dog ownership and contact with dogs, in a semi-rural community of 1278 households in Cheshire, UK. This study supported the suggestion that dogs are more common in families who have older children (6-19 years), as has been generally observed in other countries. Dog owners were also more likely to have contact with dogs other than their own, compared with those not owning a dog. A questionnaire survey of 260 dog owning households in this community found that the contacts that these dogs have, with people and other dogs, were highly variable and affected by: size, gender and age of dog; individual dog behaviours; human behaviours and human preferences in management of the dog. A number of situations were identified that may be of particular importance in relation to zoonoses, including: sleeping areas, playing behaviours, greeting behaviours, food sources, walking, disposal of faeces, veterinary preventive treatment and general hygiene. Faecal samples were provided for 183 of the dogs and forty-six (25%) were identified, by either culture or direct PCR isolation methods, as carriers of the zoonotic pathogen Campylobacter upsaliensis. Multivariable logistic regression identified risk factors for C. upsaliensis carriage as: living with another positive dog; living in a household with pet fish; size of dog; age of dog; being fed commercially-bought dog treats; and being fed human food tit-bits (particularly the act of feeding leftovers in the bowl, although letting the dog feed directly from a plate had a protective effect). These results have implications for prevention of C. upsaliensis carriage in pet dogs and the subsequent possible transmission to people. Social network analytical approaches were used to investigate potential networks arising amongst 214 of the dog owning households, through their utilisation of public space during walking. A high level of potential contact was demonstrated and this has implications for infectious disease transmission. Most households walked their dogs in only a few areas, but a small number visited many areas. In addition, behavioural observational studies of focal dogs were used to investigate the interactions with other dogs, people and the environment that may occur on dog walks. Dogs were observed to interact with other dogs much more commonly than with people. A multivariable model of percentage duration spent sniffing suggested that day of observation, UK Kennel Club Breed Type and observing urination were important. Whether a dog is on lead or not whilst on a walk: could affect the frequency in which it interacts with other dogs and people that it meets. An experimental study of ten dogs was conducted and hierarchical multilevel modelling suggested that lead status of both dogs in an interaction is important in influencing whether or not the interaction will occur; therefore if used as an intervention for reducing disease spread, both dogs should be on a lead. The work in this thesis provides new insight into the dog-human. relationship and presents information of use to those interested in reducing infectious disease transmission between dogs, and between dogs and people.
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Carioto, Lisa M. "Telomerase activity in normal dogs and dogs with malignant lymphoma." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0021/NQ47384.pdf.
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Dora, Adriano Barile. "Utilização de células-tronco mesenquimais de medula óssea canina associadas ao uso de implantes metálicos no reparo de fraturas distais de rádio e ulna em cães de raças toy: estudo complementar com coelhos da Nova Zelândia." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/10/10132/tde-12012015-163247/.
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A terapia celular é uma ferramenta que tem se mostrado eficiente para o tratamento de várias patologias veterinárias em estudos experimentais e clínicos, incluindo a estimulação osteogênica para o tratamento de não união e reparo de fraturas distais de rádio e ulna em cães. Muitas são as vantagens da utilização de células-tronco, ela é um tipo diferenciado de célula com alta capacidade de proliferação, auto renovação, produção de diferentes linhagens celulares e regeneração de tecidos, estando presente em embriões, células de cordão umbilical e medula óssea.O objetivo deste trabalho foi a avaliação clínica e radiográfica de pacientes com fraturas distais de rádio e ulna após cirurgia e tratamento com células-tronco de medula óssea de fetos caninos diretamente no foco da fratura. As avaliações radiográficas mostraram cicatrização óssea a partir de 45 dias pós-cirurgia nos dois grupos estudados, somente com cirurgia convencional e implantes e também no grupo da cirurgia convencional com implantes associada à terapia com células-tronco de medula óssea. Mostrando assim, que a terapia celular pode ser uma ferramenta favorável para auxiliar na consolidação óssea de fraturas distais de rádio e ulna. Paralelamente, realizamos um estudo com coelhos da Nova Zelândia para avaliar radiograficamente e histologicamente o uso de um scaffold esponja de colágeno com células tronco de medula óssea em modelo de fratura similar ao encontrado em cães realizado neste presente estudo, e observamos que um scaffold com células no local da fratura pode auxiliar de forma significativa na consolidação óssea.<br>Cell therapy has been an effective tool for the treatment of several animal diseases in experimental and clinical studies, including osteogenic stimulation for the treatment of non-union and repair fractures of distal radius and ulna in dogs. There are many advantages of using stem cells since this differentiated cell type has high proliferation capacity, self renewal, production of different cell lines and tissue regeneration, being present in embryos, cells from umbilical cord and bone marrow. The aim of this study was to perform a clinical and radiographic evaluation of dogs with distal radius and ulna fractures after surgery and treatment with stem cells from canine fetuses bone marrow directly into the fracture. Radiographic evaluations showed bone regeneration from 45 days post-surgery in both groups, only with conventional surgery and implant and also in the conventional surgery group with implants associated with stem cells from bone marrow therapy. Thus, cell therapy can be a favorable tool to assist in bone healing of distal fractures of radius and ulna. In parallel, we conducted a study with New Zealand rabbits for radiologically and histologically evaluate the use of a scaffold - collagen sponge with bone marrow stem cells - similar to that found in the fracture model in dogs performed in the present study, and we observed that an scaffold with cells on fracture site can help significantly in bone healing.
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Sallander, Marie. "Diet and activity in Swedish dogs /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 2001. http://epsilon.slu.se/avh/2001/91-576-5840-4.pdf.
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Kristensen, Signe Frost. "Are mixed-breed dogs healthier than purebred dogs? A review of the current data on diseases and longevity in dogs." Thesis, Linnéuniversitetet, Institutionen för biologi och miljö (BOM), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-96779.
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In today’s world, more than 400 different dog breeds have been registered and the number continues to increase, as people come up with new ways of breeding dogs. Purebred dogs are prone to many inherited disorders, inbreeding depression and a decreasing gene pool. Mixed-breed dogs, on the other hand, are said to be less prone to these problems, as they have a higher genetic variation. This review combined knowledge from the last 25 years of research in the field of mixed-breed dogs and purebred dogs to see what we know and what we still need to examine further. The literature all in all agrees that mixed-breed dogs have an increased longevity, although other factors determine longevity other than breed. They also have a decreased risk of some of the major diseases such as organ disorders and cancer but are instead prone to other problems such as ruptured cranial cruciate ligament, behavioural problems such as aggression, accidents and diabetes. Future research needs to take the inverse relationship of body mass and longevity into account when measuring longevity between breeds and more studies should be made in the field of canine cancer, as this accounts for most deaths overall in dogs.<br>I dagens värld har mer än 400 olika hundraser registrerats och antalet fortsätter att öka gradvis, eftersom människor kommer med nya sätt att avla hundar. Renrasiga hundar kan ha stora problem med ett flertal ärftliga störningar, inavelsdepression och en minskande gen pool. Å andra sidan sägs hundar med blandad ras vara mindre benägna för dessa problem, eftersom de har en högre genetisk variation. Denna översyn sammanfattar kunskap från de senaste 25 årens forskning inom området blandade hundar och renrasiga hundar för att se vad vi vet och vad vi fortfarande behöver undersöka ytterligare. Litteraturen är överens om att hundar med blandad ras har en ökad livslängd, även om andra faktorer avgör livslängder än rasen. De har också en minskad risk för några av de huvudsakliga sjukdomarna som organ defekter och cancer, dock kan de ha andra problem såsom brustet kranialkorsband, beteendeproblem som aggression, olyckor och diabetes, vilket påverkar livslängden. Framtida forskning måste ta hänsyn till det omvända förhållandet mellan kroppsmassa och livslängd vid mätning av livslängd mellan raser. Fler studier bör göras inom området cancer hos hundar, eftersom detta står för de flesta dödsfall totalt sett hos hundar.
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Shannon, Mike. "Special Dogs...Special Trainers." College of Agriculture, University of Arizona (Tucson, AZ), 1987. http://hdl.handle.net/10150/295524.
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Porter, Karen. "Dogs in a Village." Master's thesis, University of Central Florida, 2006. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/2921.
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Nearly all of the histories of Shays's Rebellion point to debt as the reason why farmers in western Massachusetts rose against the courts and the state government in the fall and winter of 1786-87. Recent scholarship demonstrates a new line of reasoning based on the tax records of those involved. The following thesis, a screenplay, offers a fictional telling of this insurgency. The story is told using language pulled from contemporary letters and documents and follows a line of causation pointing to inequitable state tax structure and poor representation as the provocation. The response that ensued was not a rebellion – it was a Regulation.<br>M.A.<br>Office of Liberal and Interdisciplinary Studies<br>Arts and Sciences<br>Liberal Studies
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Wallentine, Kari D. "Thunderstorm phobia in dogs." Thesis, Kansas State University, 2008. http://hdl.handle.net/2097/11975.
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Master of Science<br>Department of Animal Sciences and Industry<br>Janice C. Swanson<br>Canine thunderstorm phobia is a common, frustrating, and complex problem that, due to
the often severe nature of the clinical signs, can lead to canine relinquishment to shelters.
Although a potentially treatable disorder, existing treatment options have several limitations and
variable success rates. Three survey-based studies were conducted to increase the knowledge
base for canine thunderstorm phobia.
The first study distributed 1445 surveys through 16 Kansas veterinary clinics to
determine the prevalence and characteristics of thunderstorm phobic dogs and assess differences
between affected and non-affected dogs. Of 463 dogs surveyed, 240 were thunderstorm phobic
as assessed by their owners. Severe weather warning systems may play a role in thunderstorm
phobia. Thunderstorm phobic dogs were more fearful when exposed to tornado sirens, both
during actual storms and siren testing, indicating a possible effect of classical conditioning. No
differences were noted regarding sex, breed, pedigree, or neuter status. Most affected dogs
preferred to be indoors remaining near their owners.
The second study distributed 1600 surveys through eight Kansas animal shelters to
determine the prevalence of relinquished dogs with thunderstorm phobia. Other reasons for
relinquishment were also assessed. A fear of thunder was among the least common behavioral
problems leading to relinquishment in dogs. Only a quarter of owners had visited a veterinarian
for assistance with behavioral problems.
The third study involved the administration of dog appeasing pheromone (DAP) in a
double-blind, placebo-controlled, randomized clinical trial to assess its efficacy as a sole
treatment for thunderstorm phobia. Data was collected from 60 dog owners using behavioral
assessment questionnaires. In dogs given the placebo, six behaviors significantly improved, with
another eleven showing a numerical trend toward improvement. However, in dogs given DAP,
significant improvement was seen in three of these same behaviors. Consequently, these results
do not indicate the potential use of DAP for reducing fearful behaviors associated with
thunderstorm phobia when compared to negative controls. Information gained from these studies allows veterinarians and behavioral researchers to
better understand the extent of this behavioral disorder and hopefully stimulates future research
to find new and more effective ways to treat it.
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Hansson, Kerstin. "Diagnostic imaging of cardiopulmonary structures in normal dogs and dogs with mitral regurgitation /." Uppsala : Dept. of Biomedicine and Veterinary Public Health, Division of Diagnostic Imaging and Clinical Pathology, Swedish Univ. of Agricultural Sciences, 2004. http://epsilon.slu.se/v167.pdf.
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Ratcliffe, Victoria Frances. "How dogs hear us : perception of the human voice by domestic dogs (Canis familiaris)." Thesis, University of Sussex, 2016. http://sro.sussex.ac.uk/id/eprint/61052/.
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Domestic dogs have co-habited with humans for at least 15000 years. Close social interaction between the two species has promoted inter-specific communication and dogs now show advanced skills in responding to human signals in comparison to wolves. However, research into dogs' abilities to interpret human signals has predominantly focussed on visual gestures, while their responses to vocal signals remain under-investigated. Exploring the perception of human speech by dogs, a phylogenetically distant species, could provide new insights into the evolution of mammal communication. Therefore, the aim of this thesis is to assess human speech perception by dogs. Speech is composed of two main communicative components: the segmental phonemic cues carrying the linguistic content and the supra-segmental cues transmitting information about the speaker such as their gender, age and emotional state. I first explore how dogs perceive supra-segmental cues, determining that they are capable of the cross-modal discrimination of human gender. I then provide a review detailing the mechanisms underlying cross-modal associations in mammal communication, before testing which of these mechanisms may enable dogs to cross-modally associate cues to human age. The results indicate that dogs learn to match some voices to humans according to their age category, while also perceiving more general cross-modal correspondences in the environment. Finally, I investigate how dogs dissociate the main communicatory components of speech during processing, providing evidence that dogs differentially process segmental and supra-segmental cues according to their communicative content. In doing so, dogs appear to express parallel hemispheric biases to those reported in humans. Additionally, the results provide the first clear demonstration that dogs attend to the combinatory structure of the phonemic content in learnt commands. Overall, this thesis extends our knowledge of dogs' perception of human signals, indicating that they are capable of perceiving each of the main components of speech in a functionally relevant manner. Together the results suggest that dogs share some of the cognitive and social processes involved in speech perception with human listeners.
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Dismukes, David Ivan Fox Derek Bradford. "Characterization of the alignment of the canine pelvic limb." Diss., Columbia, Mo. : University of Missouri-Columbia, 2009. http://hdl.handle.net/10355/6716.
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Thesis (M.S.)--University of Missouri-Columbia, 2009.<br>The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Thesis advisor: Dr. Derek B. Fox. "May 2009" Includes bibliographical references.
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Steinbach, Sarah. "Renal and extrarenal handling of urea in healthy dogs and dogs with chronic kidney disease /." [S.l.] : [s.n.], 2009. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.
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Huang, Hui-Pi. "Studies of the microenvironment and microflora of the canine external ear canal." Thesis, Connect to e-thesis, 1993. http://theses.gla.ac.uk/678/.
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Torres-Pereira, Carla Maria Calçada. "Behavioural and physiological characterisation of responses to learning and training in dogs." Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708772.
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Packer, Rowena M. A. "Quantitative investigation of healthy conformational limits in domestic dog breeds." Thesis, Royal Veterinary College (University of London), 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618296.
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There are increasing concerns that some pedigree breeding practices compromise canine welfare; with many breeds affected by inherited disorders likely due to adherence to breed standards that encourage exaggerated conformations. Consequently, calls for quantitative limits to be included in breed standards have been advocated to safeguard against conformations that are detrimental to canine welfare. This thesis explores the relationships between extreme conformation and disease-risk, to identify the most at-risk conformations currently being selected for, and recommend healthy 'limits'. Three conformation-related disorders of high welfare importance were investigated; brachycephalic obstructive airway syndrome (BOAS), intervertebral disc extrusion (IVDE) and corneal ulceration. Seven hundred dogs entering the RVe's small animal referral hospital were recruited over 14-months; their conformations quantified using established protocols and disease-status assessed. Generalised linear mixed-model analyses demonstrated for the first time that: (1) relatively shorter muzzles and relatively thicker necks increased the risk of BOAS; (2) relatively longer backs, miniaturisation and being overweight increased the risk of IVDE; and (3) the presence of nasal folds, relatively short muzzles, relatively larger eyelid openings and the presence of exposed sclera increased the risk of corneal ulcers. To test the risk estimates generated from this population, a second study of BOAS was carried out in a non-referral population. Short muzzles and thick necks were confirmed to be risk factors for BOAS, with two further lifestyle risk factors identified: obesity and neutering. A questionnaire-based study discovered an owner-perception of BOAS being 'normal for the breed' that may hamper efforts to reduce its prevalence in the future. As such, educational interventions to change attitudes may be required. The results of these studies are hoped to instigate and inform future breed standard revisions, and influence those within the breeding community to change current breeding practices to improve canine welfare by selecting for more moderate, lower-risk morphologies.
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Maxwell, Megan E. "The relative efficacy of three procedures for reducing canine responding." Morgantown, W. Va. : [West Virginia University Libraries], 2008. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=5567.
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Thesis (Ph. D.)--West Virginia University, 2008.<br>Title from document title page. Document formatted into pages; contains vi, 61 p. : ill. Includes abstract. Includes bibliographical references (p. 54-61).
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Britt, Winard Bevly David M. Hamilton John A. "A software and hardware system for the autonomous control and navigation of a trained canine." Auburn, Ala, 2009. http://hdl.handle.net/10415/1800.
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Holton, Lynne Louise. "The measurement of pain in dogs." Thesis, University of Glasgow, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366201.
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Hilby, Elly. "The welfare of kennelled domestic dogs." Thesis, University of Bristol, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.424076.
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Fall, Tove. "Characterisation of diabetes mellitus in dogs." Uppsala : Dept. of Clinical Sciences, Swedish University of Agricultural Sciences, 2009. http://epsilon.slu.se/200945.pdf.
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Heurlin, Jasmine. "Behavioral synchronization between dogs and owners." Thesis, Linköpings universitet, Biologi, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-157382.
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Dogs have lived with us for thousands of years, so we have learned to understand one another. Dogs have been shown to synchronize their behavior with humans. Behavioral synchronization is characterizes by doing the same thing at the same time and in the same place as someone else. This synchronization is often dependent on the relationship and the emotional state of the individuals. The main aim in this study was to develop a method to test behavioral synchronization and also to investigate how this, but also other behaviors, are effect by preceding human-dog interactions. Privately owned dogs (N=21) were tested with three different treatments (play, pet or ignore). The test procedure consisted of the owner walking or standing still in a predefined pattern, while their dog was freely roaming. This study showed that dogs adapted their movement pattern to their owners. This was similar to previous studies showing that the method developed can be used to test behavioral synchronization between owner and dog. Dogs explored the test arena less after play interaction and they also tended to seek more eye contact with their owners, but the interactions did not affect how much time spent in human proximity, how much they followed them or on dogs movement pattern.
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Cochrane, Parra George Benjamín, Rojas Carlos Javier Flores, Serna Felices Jorge Daniel La, and Sanchez Darcy Luz Perez. "Guardería y hotel canino - Wasi Dogs." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/626264.
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Nuestro proyecto está dirigido a clientes “Dog lovers” que han desarrollado un vínculo afectivo con sus perros. La creciente demanda de familias con los “hijos de cuatro patas”, se encuentran en la necesidad de invertir en ellos.
En el estudio del entorno encontramos que en Lima el 41% de los hogares cuentan un perro como mínimo en casa. Las personas de los sectores A y B, son los más propensos a invertir en emprendimientos como el nuestro, por ello nos enfocaremos en los distritos de San Isidro, San Borja y Miraflores.
Para conocer la opinión del segmento se implementó entrevistas a profundidad e identificamos que un porcentaje del mercado se encuentra desatendido y que existen necesidades por cubrir.
El plan de operaciones establece un local 5,000 mts2. Inicialmente sólo el 40% será implementado con infraestructura para el entretenimiento y cuidado de los canes. El 60% se implementará en el transcurso de los 3 años de actividad.
La viabilidad del proyecto se sustenta en que se ha obtenido un VPN del Flujo de caja de Libre disponibilidad S/ 448.703,18 a una tasa WACC 13.83%, un VPN del flujo de caja del inversionista de S/ 398.661,46 a una tasa COK del 16 %. Finalmente el periodo de recuperación descontado resulta 3.29
En base a los resultados mostrados, se concluye que el presente emprendimiento proyecta ser rentable debido a que ha generado mayor al retorno esperado por los accionistas e inversionistas.<br>Our project targets are the "Dog Lovers", people who have developed an affective bond with their dogs. The growing demand of families with their "four legged kids", resides in the need to invest in them.
The research of environment showed us that just in Lima city, 41% of homes have at least, one dog at home. The people from sectors A and B are willing to invest in ventures like ours, so we decided to focus on San Isidro, San Borja and Miraflores districts.
In-depth interviews were necessary in order to obtain greater clarity and knowledge about concerns and opinions of the segment. We identified that a significant percentage of the market is unattended and there are needs and opportunities to cover.
The operational plan establishes a site of 5,000 m2. According to this, initially just the 40% will be implemented with infrastructure for the entertainment and caring of dogs. The remaining 60% will be implemented later, along the 3 years of activity.
The viability of the project is based on the fact that a Free Availability Cash Flow NPV of S / 448,703.18 has been obtained at a WACC rate of 13.83%, an NPV of the investor's cash flow of S / 398,661.46 at a COK rate of 16%. Finally, the discounted recovery period results 3.29.
Based on the results shown, it is concluded that the present venture is projected to be profitable because it has generated a higher return expected by shareholders and investors.<br>Trabajo de investigación
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Khazal, Kamel F. "Chloramphenicol pharmacokinetics and metabolism in dogs /." The Ohio State University, 1986. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487267024996335.
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Schwartz, Denise Saretta. "Studies on baroreceptor function in dogs /." The Ohio State University, 2000. http://rave.ohiolink.edu/etdc/view?acc_num=osu1488202678774537.
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Caddy, Sarah. "Characterisation of enteric viruses in dogs." Thesis, Imperial College London, 2015. http://hdl.handle.net/10044/1/39793.
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Human noroviruses (HuNoV) are a significant cause of viral gastroenteritis in man worldwide. Noroviruses are also associated with intestinal disease in multiple species, including dogs. Canine norovirus (CNV) was initially discovered in 2007 and the first aim of this thesis was to determine the prevalence of CNV in the UK dog population. qPCR screening of canine stool samples did not identify CNV RNA, but canine astroviruses (CaAstV) were serendipitously identified and subsequently characterized according to the second aim of this work. For serological screening, CNV virus-like particles (VLPs) to three CNV strains were produced. CNV circulation in the UK was confirmed by identification of CNV-specific antibodies in 60% of canine serum samples collected in 2012-2013. The third aim of this thesis was investigate to CNV interactions with host cells by identifying the cellular attachment factor for CNV. Synthetic carbohydrates and canine tissue samples were used to assess the binding specificity of CNV VLPs, and it was shown that antigens of the HBGA family were recognized. Phenotyping studies then demonstrated expression of HBGAs in dogs. As HuNoV also uses HBGAs to attach to cells, this raised concerns that dogs may be susceptible to HuNoV. Evaluating the zoonotic risk of enteric viruses in dogs was the final aim of this thesis. The susceptibility of dogs to HuNoV and hepatitis E virus (HEV) was determined by screening canine samples for the presence of HuNoV or HEV RNA and HuNoV or HEV-specific antibodies. Antibodies to both HuNoV and HEV were identified in dogs, and results confirmed HuNoV VLPs can bind to canine gastrointestinal samples. This data indicates that dogs are susceptible to HuNoV and HEV infections. In conclusion, this thesis has provided epidemiological and molecular characterization of CNV and CaAstV, in addition to highlighting the zoonotic potential for CNV, HuNoV and HEV in dogs.
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Grant, David C. "Measurement of urinary glycosaminoglycans in dogs." Thesis, Virginia Tech, 2003. http://hdl.handle.net/10919/33614.
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Recent work in humans with protein losing nephropathies has revealed increased urine concentrations of sulfated glycosaminoglycans (GAGs). Differences exist between normal patients, those with glomerulonephritis (GN), and those with amyloidosis thus potentially allowing differentiation without a renal biopsy. Aims of this study were to validate a simple spectrophotometric assay used to measure canine urinary GAGs, establish a normal reference range, and determine optimal storage conditions. Urine GAG concentrations were measured in a limited number of dogs with glomerulonephritis or amyloidosis.
Fourteen healthy dogs were placed in metabolic cages and all urine was collected for 24 hours. Serum and urine creatinine concentrations were measured at the beginning and end of the collection period. Urine collected at the beginning of the 24-hr period was centrifuged and the supernatant used to measure a spot GAG concentration and a spot glycosaminoglycan to creatinine ratio (GCR). A well mixed aliquot of the 24-hr sample was centrifuged, the supernatant used to measure the 24-hr total GAG, and stored at 4°C and -20°C for 1, 7, and 30 days. All dogs were used to determine effects of time and temperature (n=14), however, only dogs with an endogenous creatinine clearance > 2 ml/min/kg (n=10) were used to determine normal values. A standard absorption curve using a 1,9-dimethlymethylene blue dye and dilutions of chondroiton-4-sulfate was developed to estimate total GAG concentration. Repeated measures analysis of variance was used to test for effects of storage temperature and time on stability of urinary GAG. A p-value of < 0.05 was considered significant. Relationships between spot urinary GAG concentration, spot urinary GAG to creatinine ratio (GCR) and 24-hr total GAG excretion were estimated using simple linear regression. Single urine samples were collected by cystocentesis from dogs with GN or renal amyloidosis. The diagnosis was confirmed by clinical evaluation or by histologic analysis. Urine protein, creatinine and GAG concentrations were measured.
There were no time or temperature effects on urine GAG concentrations for up to 1 day at 4°C and 30 days at -20°C. Mean 24-hr total GAG excretion ± standard deviation was 1.586 ± 0.461 mg/kg of body weight. Mean spot GAG concentration and spot GCR were 5.007 ± 1.588 mg/dl and 0.023 ± 0.01 respectively. Neither spot GAG concentration (R2=0.4216) nor GCR (R2= 0.0839) were adequate predictors of 24-hr total GAG. The GCR's from dogs with renal disease were not different from normal dogs.
This study established normal total urinary GAG values in dogs. Contrary to findings in humans, there was no correlation between 24-hr total sulfated GAG and spot GCR in dogs, limiting clinical utility of this test. Further work is needed to determine if either total sulfated GAG or the spot GCR can be used to differentiate causes of protein-losing nephropathies in dogs.<br>Master of Science
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Ayres, Sara A. "Electrodiagnostic evaluation of facial nerve function in normal dogs and dogs presented for total ear canal ablation." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ35783.pdf.
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Swenson, Lennart. "Population studies on genetic diseases in the dog /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 2001. http://epsilon.slu.se/avh/2001/91-576-5822-6.pdf.
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McKnight, Debra Gayle. "Breaking Accidental Behavior Chains." Thesis, University of North Texas, 2010. https://digital.library.unt.edu/ark:/67531/metadc28453/.
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Accidental behavior chains are a common problem in dog training. Many handlers inadvertently reinforce undesirable behaviors. The behavior analytic literature already contains articles describing methods of breaking chains; however, those methods either are not used in dog training for practical purposes or are ineffective in dog training. This experiment investigated two ways to break a behavior chain, including extending the chain and introducing a delay into the chain. The results of extending the chain showed that it is possible to decrease the target behavior using this method, but it was not eliminated in this study. Adding a delay into the behavior chain resulted in a quick elimination of the target behavior.
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Melville, Scott Andrew Biotechnology & Biomolecular Sciences Faculty of Science UNSW. "Disease gene mapping in border collie dogs." Awarded by:University of New South Wales. School of Biotechnology and Biomolecular Sciences, 2006. http://handle.unsw.edu.au/1959.4/25511.
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Pedigree dog breeds are genetically isolated and inbred populations with characteristics specific to each breed. Some breeds carry genetic diseases which affect the health of the animals, but may also serve as a valuable model to identify genes involved in human disease. In the Border Collie breed in Australia, the identification of two disease genes would enable breeders to DNA test their animals and prevent future cases. Over 530 samples were collected to identify the genes responsible for these diseases through linkage mapping and candidate gene approaches. Collie Eye Anomaly (CEA) defines a group of symptoms that cause the incorrect development of different regions within the eye, and may also result in the detachment of the retina. The presence of the disease in different breeds of collies suggests that the disease originated before the differentiation of the collie breeds. The CEA gene was mapped to a region of CFA37, but the disease gene was identified by another research group. Neuronal Ceroid Lipofuscinosis (NCL) is a fatal neurodegenerative disorder that affects Border Collie dogs from approximately 16 months of age. The disease is inherited in an autosomal recessive manner and affected animals display a range of physiological and behavioural symptoms that include loss of muscular control, nervousness and sometimes aggression. Due to the debilitating nature of the disease, dogs rarely survive beyond 28 months of age. Microsatellite markers were used to exclude the Border Collie NCL gene from the region of the English Setter NCL gene (homolog of human NCL gene CLN8). Further work mapped the disease gene to CFA22, in a region containing the homolog for CLN5, one of the identified human disease genes for NCL. Subsequent sequencing of canine CLN5 revealed a nonsense mutation (c.619C>T, Q206X) that co-segregated with NCL in Border Collie pedigrees. This truncation mutation resulted in a protein product of similar size to some mutations identified in human CLN5 and therefore the Border Collie may make a good model for future NCL studies. With DNA testing now available, breeders of Border Collies can now ensure that no animal will die of NCL.
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Kiddie, Jenna L. "Assessing quality of life in kennelled dogs." Thesis, Royal Veterinary College (University of London), 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.572476.
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Gong, He [Verfasser]. "Lumbosacral Transitional Vertebrae in Dogs / He Gong." Berlin : Freie Universität Berlin, 2019. http://d-nb.info/1192304209/34.
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Wilshaw, Joanne. "Measuring attachments between dogs and their owners." Thesis, University of Exeter, 2010. http://hdl.handle.net/10871/14277.
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This thesis details the development and testing of a new scale for measuring human attachment to dogs which allows for the measurement of weaker attachment levels as well as stronger ones (the CDA scale). The correlation between dog-owner’s scores on the CDA scale and their dog’s actual attachment behaviour is assessed and discussed, as well as the dog-owners limited ability to predict the behaviour of their dog in a controlled situation (the Strange Situation Test (SST)) whereby the dogs meet a previously unknown person. The CDA scale was formed by utilising items from pre-existing scales (the Comfort from Companion Animals scale and the Lexington Attachment to Pets scale), trialed on the internet with a large self-selected sample of dog-owners and analysed and reduced using factor analysis. The CDA was completed with the addition of some negative items derived from a small sample of dog-owners who expressed drawbacks to keeping a dog. In addition 100 people living with dogs they did not consider themselves to be the primary carer of, and 100 people with dogs they considered to have behavioural problems also completed the CDA to allow for the assessment of reliability and validity, and for consideration of the possible links between human perceptions of attachment/dog behavioural problems and actual scores on the CDA. Dogs’ attachment behaviour was assessed by cluster analysis of behaviours observed in the SSD: 51 dog-owner pairs took part in the study which revealed a number of secure-base behavioural categories analogous to those typically observed in human mother-infant interactions in Ainsworth’s original (1969) SST. In addition five captive wolves were also observed in a modified version of the SST. Data from these observations is discussed in a case-wise manner and it is clear that captive wolves do not exhibit the suite of attachment behaviours (to their familiar handler) as previously observed in the dog study. However, the wolves’ familiar handler was very adept at predicting the behaviour of his wolves in this situation. These findings are important in furthering our understanding of human-canine attachments in general, but especially given the number of dog-owner pairings which appear to fail due to poor or misunderstood attachments. An effective attachment scale for people, and a valid measure and analysis of attachment behaviour in dogs is a further development in ensuring successful pairings of people with dogs in a variety of contexts such as pet dogs and service dogs.
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Smith-Bickel, Janas R. "Motivation and the dogs who influenced me." Virtual Press, 1993. http://liblink.bsu.edu/uhtbin/catkey/864943.
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The desire I have to make visual images has been fueled by my interest in the parley between man and animal. Throughout history, artists have been intrigued by the relationship between man and animal, an intrigue which has evolved into sane contemporary work.Through this series of nine paintings, the message I impart is the importance of mankind's consideration of animal welfare and that animals are dignified, capable of selfhood and deserving of respect.Through the use of them as my subjects, my dogs, Zeek and Hogan, become the domesticated messengers. I use vivid color, odd perspectives, natural poses and environments, the incorporation of pattern and thick application of the paint to convey my opinions.I learned more about myself and my relationship to the dogs who share my life. It is important to me to make images of my feelings about animals and to educate others about the importance of their well-being.<br>Department of Art
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Burnell, Matthew Gregory. "The scaling of acute pain in dogs." Thesis, University of Glasgow, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.411848.
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German, Alexander James. "Immunological studies of chronic enteropathies in dogs." Thesis, University of Bristol, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313080.
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Katz, Morgan. "Constructional Fear Treatment for Dogs in Shelters." Thesis, University of North Texas, 2016. https://digital.library.unt.edu/ark:/67531/metadc862823/.
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Of the approximately 3.9 million dogs that enter US animal shelters each year, many exhibit behaviors related to fear, which can affect their likelihood of adoption. Current dog training procedures to treat fear include counterconditioning and desensitization, which can often take months or years to show any behavior change and do not teach specific behaviors aimed to increase the dog's chance of being adopted. The current study used a negative reinforcement shaping procedure to teach fearful dogs to approach and and interact with people. The results showed that constructional fear treatment increased the amount of time the dog spent at the front of the kennel, and increased sniffing, tail wagging, and accepting petting for all 3 participants.
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Sarvis, Nancy Q., Andrea D. Clements, and Tifani A. Fletcher. "Salivary Cortisol Levels of Working Therapy Dogs." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/7256.
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Research documenting the level of work-related stress among therapy dogs is limited. This research was designed to measure salivary cortisol in working therapy dogs. Certified handler/dog (Canis lupus familiaris) teams were recruited to participate from teams currently volunteering in the Tri-Cities, Tennessee area. Male and female dogs of various sizes and breeds were recruited. Ten dogs contributed fivesaliva samples. Dogs were fasted for one hour prior to procedure. Samples were collected over a continuum of events, for comparison of salivary cortisol levels in multiple environments. Samples were collected as follows: (1) sample in the dogs’ homes, (1)sample upon arrival at the “work” place, (1) sample just prior to leaving the “work” place, (1) sample just prior to being groomed and (1) sample taken at the dogs’ regular veterinarians’ offices. This design provided 1 control sample, 2 work samples, and2 samples that may be indicative of elevated stress. It was hypothesized that: 1) Salivary cortisol concentrations will be higher in samples collected during grooming and at a veterinary clinic than in samples collected at home, and 2) Salivary cortisol concentrations will be lower in samples collected during “working” conditions than in samples collected during grooming and at a veterinary clinic. Saliva was collected by placing a Salimetrics Children’s Swab (P/N 5001.06) [dimensions 8 x 125 mm] into the dog’s mouth until saturated, or less than four minutes. After examination of the descriptive statistics of (n=10) across five different environmental conditions, it was decided that one of the cases represented an outlier and was removed from data as subsequent analysis revealed a cortisol level that was more than 23 standard deviations away from the mean. Three dogs had at least one sample with insufficient quantity of saliva for analysis, and were removed from the data. A one-way repeated measures ANOVA was conducted to compare salivary cortisol levels during different environmental conditions (pre-therapy, post-therapy, home, veterinary clinic, and groomer). There was not a significant main effect for condition, Wilks’ Lambda =.299, F (9, 2) =1.17, p=.51,multivariate partial eta squared = .70. The hypotheses were not supported. This research suggests that salivary cortisol of working therapy dogs is not significantly different than home, veterinary, or grooming conditions.
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Gallivan, Sean Thomas. "Safety of Epidurally Administered Ketorolac in Dogs." Thesis, Virginia Tech, 1999. http://hdl.handle.net/10919/33874.
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The objective of this study was to evaluate the clinical, cerebrospinal fluid (CSF), and histopathologic effects of an epidurally administered NSAID (ketorolac) in dogs. This was performed as a blinded, placebo controlled study using twenty-two adult mixed breed dogs with 16 treatment and 6 control dogs. Dogs were anesthetized and epidural catheters were placed at the lumbosacral space. Catheter placement was evaluated fluoroscopically. Ketorolac (0.4 mg/kg) or placebo (5% ethanol) was administered epidurally over a 52 hour period, with 5 injections given at 12 hour intervals. At 1, 2, 4, or 8 hours after the first and last injection of ketorolac, dogs were anesthetized and CSF was obtained. Control dogs had CSF sampled 1 hour after the first and last ethanol injection. Neurologic function and pain response was evaluated before and during the study. Selected dogs were then euthanized and necropsies performed.
None of the dogs exhibited any clinical or neurological abnormalities during the study. No statistical difference was noted in pain response or CSF analysis between treatment and control dogs. Gross necropsy revealed gastrointestinal ulceration of varying degrees in all treatment dogs. Histopathologic analysis of the spinal cord and meninges revealed minimal focal leptomeningeal phlebitis in 2 of 8 treatment dogs and minor subdural inflammation in one control dog. No changes to the neural structures were noted in any dogs.
Epidural administration of ketorolac did not cause clinical signs, alteration in CSF values, or pathologic changes to the spinal cord when used for short duration. Gastrointestinal ulceration was common when ketorolac was administered epidurally at 0.4 mg/kg every 12 hours for 5 treatments.
This study documented the safety of epidurally administered ketorolac in dogs before an efficacy trial can be performed. Gastrointestinal ulceration may limit use to short duration or single injection.<br>Master of Science
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Demonaco, Stefanie. "Natural History of Biliary Sludge in Dogs." Thesis, Virginia Tech, 2015. http://hdl.handle.net/10919/56557.
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Background: Biliary sludge is associated with gallbladder (GB) dysmotility and mucus hypersecretion suggesting that these factors could lead to GB mucoceles. If biliary sludge does progress to GB mucoceles, treatments to reduce the production and progression of sludge are warranted.
Objectives: The aim of this study was to determine the natural history of biliary sludge in dogs.
Animals: Healthy, client-owned dogs (n=74) screened for biliary sludge; 42 affected dogs identified
Methods: Prospective, observational design. Serial ultrasound examinations and biochemistries were evaluated over 1 year. The following were determined: percentage of the GB filled with sludge (mild (0.01%-24.4%), moderate (24.5%-49.4%), moderate to severe (49.5%-74.4%), severe (74.5%-100%)), gravity dependency of sludge, GB dimensions, and biochemical indices (ALT, GGT, ALP, total bilirubin, albumin, total calcium, triglycerides, and cholesterol). Mixed model ANOVA, Friedman chi-square, Mantel-Haenzsel chi-square tests, and Kruskal-Wallis test were performed to detect significant changes in these parameters. Significance at P <0.05.
Results: After 1 year of follow-up, the percentage of the GB filled by sludge was mild (34%), moderate (47%), moderate to severe (13%), severe (3%), or absent (3%) with no significant difference in the median degree of biliary sludge within 1 year (P=0.36). There was no significant change in the gravity dependency of sludge over 1 year. Dogs had resolved (2%), decreased (19%), static (40%), increased (29%), or recurrent (10%) sludge at the conclusion of the study. Biochemical indices or GB volume were not significantly different over time or among groups.
Conclusion: Biliary sludge is prevalent, affected dogs remain asymptomatic, and it rarely resolves in healthy dogs over a period of 1 year. Some dogs developed non-gravity dependent sludge within 1 year, which may indicate changes in consistency.<br>Master of Science
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Jittapalapong, Sathaporn. "Immune resistance to Rhipicephalus Sanguineus in dogs /." The Ohio State University, 2000. http://rave.ohiolink.edu/etdc/view?acc_num=osu1488191124572314.
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Doehring, Orlando. "Identification of breed contributions in crossbred dogs." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1464461/.
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There has been a strong public interest recently in the interrogation of canine ancestries using direct-toconsumer (DTC) genetic ancestry inference tools. Our goal is to improve the accuracy of the associated computational tools, by developing superior algorithms for identifying the breed composition of mixedbreed dogs. Genetic test data has been provided by Mars Veterinary, using SNP markers. We approach this ancestry inference problem from two main directions. The first approach is optimized for datasets composed of a small number of ancestry informative markers (AIM). Firstly, we compute haplotype frequencies from purebred ancestral panels which characterize genetic variation within breeds and are utilized to predict breed compositions. Due to a large number of possible breed combinations in admixed dogs we approximately sample this search space with a Metropolis-Hastings algorithm. As proposal density we either uniformly sample new breeds for the lineage, or we bias the Markov Chain so that breeds in the lineage are more likely to be replaced by similar breeds. The second direction we explore is dominated by HMM approaches which view genotypes as realizations of latent variable sequences corresponding to breeds. In this approach an admixed canine sample is viewed as a linear combination of segments from dogs in the ancestral panel. Results were evaluated using two different performance measures. Firstly, we looked at a generalization of binary ROC-curves to multi-class classification problems. Secondly, to more accurately judge breed contribution approximations we computed the difference between expected and predicted breed contributions. Experimental results on a synthetic, admixed test dataset using AIMs showed that the MCMC approach successfully predicts breed proportions for a variety of lineage complexities. Furthermore, due to exploration in the MCMC algorithm true breed contributions are underestimated. The HMM approach performed less well which is presumably due to using less information of the dataset.
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Morters, Michelle. "Improving rabies control in free-roaming dogs." Thesis, University of Cambridge, 2014. https://www.repository.cam.ac.uk/handle/1810/252882.
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Canine-mediated rabies is a serious zoonosis responsible for at least 55,000 human deaths every year, primarily in less developed communities in Asia and Africa where domestic dogs are free-roaming. The disease can be effectively controlled through vaccinating at least 45% of the dogs in a population; however the impact of vaccinations on disease incidence may be affected by dynamic demographic and immunological processes. Specifically, the contribution of these processes, and their regulatory factors, to vaccination coverage and rabies transmission has not been comprehensively estimated. To improve rabies control, through field interventions and epidemiological modelling, more information regarding the effect of these processes, and their regulatory factors, on population and disease dynamics and vaccinal responses was needed. This required a multifaceted approach, using techniques from the fields of population ecology, vaccine-immunology, social science and epidemiological modelling. Demographic data were collected from four populations of free-roaming domestic dogs, two in South Africa and two in Indonesia where rabies is endemic. Longitudinal, individual-level data were obtained by direct observation and surveys, and community-level data by participatory methods. Longitudinal, serological data were collected from three cohorts within the populations. Epidemiological models were based on epidemic theory and empirical data from this current study and previous studies. A wide array of data were generated relevant to planning rabies control programmes, however of particular importance was evidence regarding positive and negative the impacts of human factors on population and disease dynamics. Nearly all of the dogs were owned, despite being free-roaming, and were accessible for vaccination through their owners; and population size was regulated through human demand for dogs and a substantial fraction of dogs was acquired from outside the communities. These translocated dogs may contribute to the spread of rabies, necessitating widespread and sustained vaccination programmes. Considerable differences in the handleability of dogs between locations and, thus ease of vaccine delivery, may also be attributable to differences in human-dog interactions. Finally, a critical review of the literature, and evaluation of epidemiological models, suggests that human interference in the transmission processes may reduce the incidence of rabies and vaccination threshold. This study has provided specific evidence that human behaviours are likely to be critically important in relation to the transmission and control of canine-mediated rabies ? and is the first to properly identify this. Further detailed studies are required to explore these behaviours and how they vary culturally and geographically. In addition, the results highlight the critical role that demographic processes more generally, as well as immunological decay, play in influencing the long term success of rabies vaccination programmes. Overall, this research has provided valuable support for planning rabies control programmes and for parameterisation of epidemiological models of infectious diseases, including rabies.
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Aboim, Catarina Fânzeres de Sousa Pinto. "Gut microbiome in healthy dogs and cats." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2019. http://hdl.handle.net/10400.5/17136.
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Dissertação de Mestrado Integrado em Medicina Veterinária<br>Recent studies show that the gut microbiome contributes to the vital physiologic and immunologic processes and is influenced by external factors such as diet, environment, medical interventions, and disease states. In this study, we describe the gut microbiome of healthy dogs and cats, from households and shelters, contributing for a better understanding of the effect that environment can have on it.
The samples were collected between 2016 and 2017 and consisted of a household group (N=38, N=26 dogs and N=12 cats) and a shelter group (N=62, N=51 dogs and N=11 cats). DNA extraction was done directly from the faeces and the V4 region of the 16S rRNA gene was amplified, followed by sequencing using Illumina MiSeq. Raw sequences were treated using QIIME2 and Greengenes database was chosen for taxonomic classification alignment at 99% similarity. SAS statistical software was used, a p-value < 0.05 was considered.
The Principal Coordinate Analysis plot demonstrated that the feline and canine microbiomes were well separated, as well as the household dog samples and the shelter dog samples, meaning that there is a difference in the gut microbiome between these groups. The same conclusion was not observed for the cat samples. The phyla Firmicutes and Bacteroidetes were the predominant ones in both species. For the dog samples, there was no difference between the two groups in Firmicutes and Bacteroidetes phyla (p>0.05), but the phyla Fusobacteria and Proteobacteria were in higher percentages in the shelter group (p<0.05).
To our knowledge, this is the first study that describes and compares the gut microbiome composition of healthy household and shelter dogs and cats. This study demonstrates that the environment where animals are born and grow, as well as the amount of contact they have with humans, may have a great influence in their gut microbiome.<br>RESUMO - Microbioma entérico em cães e gatos saudáveis - Estudos recentes demonstram que o microbioma gastrointestinal tem um papel essencial nos processos fisiológicos e imunológicos do hospedeiro e que é fortemente influenciado pela dieta, ambiente, intervenções médicas e estados de doenças. Neste estudo pretendemos descrever o microbioma entérico de cães e gatos saudáveis provenientes de canis e de casas, contribuindo para uma melhor compreensão do efeito que o ambiente pode ter neste.
As amostras foram colhidas entre 2016 e 2017 e consistiam num grupo de casa (N=38, N=26 cães e N=12 gatos) e um grupo de canil (N=62, N=51 cães e N=11 gatos). Foi realizada extração de DNA diretamente a partir das fezes e amplificada a região V4 do gene 16S rRNA, seguindo-se de sequenciação com Illumina MiSeq. As sequências foram tratadas usando o QIIME2 e a biblioteca Greengenes foi escolhida para classificação taxonómica, com o alinhamento a 99% de semelhança. Foi usado o SAS e considerado um p-value<0.05.
O Principal Coordinate Analysis plot demonstrou que os microbiomas felino e canino são diferentes, assim como o microbioma de cães de casa e canil. No entanto, não foi possível chegar à mesma conclusão nas amostras de gato. Os phyla Firmicutes e Bacteroidetes foram os predominantes em ambas as espécies sendo que, nas amostras de cão, não houve uma diferença estatisticamente significativa entre os dois grupos para estes phyla (p>0.05). Os phyla Fusobacteria e Proteobacteria foram identificados com maior frequência nas amostras de canil, tendo sido esta diferença estatisticamente significativa (p<0.05).
Tanto quanto é do nosso conhecimento, este é o primeiro estudo a descrever e comparar o microbioma gastrointestinal de cães e gatos saudáveis provenientes de casa e canil. Este estudo demonstra que o ambiente em que os animais nascem e habitam, assim como a quantidade de contacto que têm com o ser humano, pode ter grande influência no seu microbioma gastrointestinal.<br>N/A
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Graham, Kristi L. "The effects of furosemide administration on glucose homeostasis in healthy dogs and dogs with alloxan-induced insulinopenic diabetes mellitus." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0001/MQ43502.pdf.
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Luther, Jill K. Cook James L. "Comprehensive characterization of canine meniscal pathology." Diss., Columbia, Mo. : University of Missouri-Columbia, 2010. http://hdl.handle.net/10355/.
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The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from PDF of title page (University of Missouri--Columbia, viewed on July 13, 2010). Thesis advisor: James L. Cook "May 2010" Includes bibliographical references.
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Broaddus, Kristyn Donnelly Tillson D. Michael. "Renal allograft histopathology in dog leukocyte antigen (DLA) mismatched dogs following renal transplantation." Auburn, Ala., 2005. http://repo.lib.auburn.edu/2005%20Summer/master's/BROADDUS_KRISTYN_22.pdf.
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