Academic literature on the topic 'Dogs – Surgery – Case studies'

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Journal articles on the topic "Dogs – Surgery – Case studies"

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Le, Thong Q. "Case report of brachycephalic obstructive airway syndrome in brachycephalic dogs from Veterinary Specialist Service Hospital, Australia." Journal of Agriculture and Development 19, no. 03 (June 30, 2020): 28–38. http://dx.doi.org/10.52997/jad.5.03.2020.

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This report aimed to study symptoms and causes of brachycephalic obstructive airway syndrome (BOAS) in brachycephalic dogs and to determine appropriate surgical procedures for these symptoms by reviewing literatures and examining four case studies conducted at Veterinary Specialist Service Hospital, Underwood, Queensland, Australia. The cases included a 6-year 3-month-old Staffordshire Bull Terrier (case 1), a 1-year 5-month-old French Bulldog (case 2), an 8-month-old French Bulldog (case 3), and an 8-year 8-month Pug (case 4). Those dogs went to the Veterinary Specialist Service in a worsen state of respiratory problems, including the upper respiratory noise (case 1, 2, 3), decrease in exercise tolerance, respiratory struggling (case 1, 3), regurgitation (case 1), coughing, sleeping difficulty, respiratory stridor (case 2), nasal discharge, dyspnea, bloating, and tachypnea (case 4). Examinations revealed the causes including the elongated soft palate (case 1, 2, 3, 4), stenotic nostrils (case 2, 3, 4), tonsils inflammation (case 3) and everted laryngeal saccules (case 4). After surgery, the dogs were recovered in intensive care unit within 2 days, and then discharged. Scheduled re-examination one week later showed improvement in the respiratory health in all cases. Overall, major complications occur in 10% of cases; however, this surgery is vital and can be totally applied in Vietnam where brachycephalic dogs have become a popular companion.
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Hoffberg, Jamie Elizabeth, and Amy Koenigshof. "Evaluation of the Safety of Early Compared to Late Enteral Nutrition in Canine Septic Peritonitis." Journal of the American Animal Hospital Association 53, no. 2 (March 1, 2017): 90–95. http://dx.doi.org/10.5326/jaaha-ms-6513.

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ABSTRACT Septic peritonitis is a relatively common condition in the veterinary intensive care unit, with a classically high mortality rate. Early enteral nutrition (EEN) in critically ill humans can lead to improved outcome. This study was performed to determine the safety of early postoperative feeding in canine septic peritonitis. In this retrospective case series, 56 dogs were identified. Sixteen dogs received EEN, defined as nutrition within 24 hr of surgery; 27 received late enteral nutrition (LEN) defined as nutrition more than 24 hours following surgery; and 13 dogs had no enteral nutrition in hospital (NEN). Signalment, physical examination findings, and occurrence of pre-admission vomiting, regurgitation, and length of anorexia were the same amongst all groups. There was no significant difference in the number of gastrointestinal complications postoperatively between the EEN, LEN, and NEN groups or in the occurrence of vomiting/regurgitation postoperatively compared to preoperatively. There was no difference in the length of hospitalization between any group, although fewer dogs in the NEN group survived compared to the EEN/LEN combined group (46% [6/13] versus 81% [37/40]). This study indicates it is safe to initiate EEN without additional risk of gastrointestinal complications. Prospective studies are needed to evaluate the potential benefits of EEN in dogs with septic peritonitis.
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Kunyuan, Jiang, Li Ao(Ngao), Pan Jin, Zhu Peifang, He Baobin, Chen Faming, Lian Weikun, Wang Tianyi, and Wu Zhengzhong. "Blood gas studies in dogs with severe steam inhalation injury." Burns 13, no. 5 (October 1987): 371–76. http://dx.doi.org/10.1016/0305-4179(87)90126-4.

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Hohenhaus, Ann E., Jennifer L. Kelsey, Jamie Haddad, Lisa Barber, Matthew Palmisano, John Farrelly, and Anita Soucy. "Canine Cutaneous and Subcutaneous Soft Tissue Sarcoma: An Evidence-Based Review of Case Management." Journal of the American Animal Hospital Association 52, no. 2 (March 1, 2016): 77–89. http://dx.doi.org/10.5326/jaaha-ms-6305.

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Canine cutaneous and subcutaneous soft tissue sarcomas (STS) account for 20.3% of malignant neoplasms of the skin. This article makes recommendations for the diagnosis, treatment, and follow-up in dogs with STS, using evidence-based medicine concepts. Although our review of the literature on the management of canine STS found many of the studies to be less than rigorous, board-certified specialists in internal medicine, surgery, pathology, oncology, and radiation oncology were able to make several recommendations based on the literature review: cytology and biopsy are important for presurgical planning; wide (>3 cm margins) surgical excision decreases the likelihood of tumor recurrence; the use of a histologic grading scale is useful in predicting biologic behavior; and, in select cases, chemotherapy and radiation therapy may be beneficial adjunct treatments to surgical excision. More research is necessary to determine minimum size of surgical margins, the impact of radiation therapy on incompletely resected tumors, the ideal chemotherapy protocol for high grade STS, and the optimal methods of monitoring dogs for tumor recurrence and metastasis.
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Yoon, HY, JW Choi, H. Kim Ji, and H. Kim Jung. "Use of a double-wire woven uncovered nitinol stent for the treatment of refractory tracheal collapse in a dog: a case report." Veterinární Medicína 62, No. 2 (February 13, 2017): 98–104. http://dx.doi.org/10.17221/15/2016-vetmed.

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A 2.7 kg, 11-year-old, castrated male Maltese dog was presented for evaluation of a 2-year history of intractable coughing, dyspnoea and cyanosis. A diagnosis of tracheal collapse with myxomatous mitral valve disease was made on the basis of inspiratory and expiratory thoracic radiographs, fluoroscopy and echocardiography. Measurement for stent size selection was performed on thoracic radiographs. A 10 mm (diameter) × 70 mm (length) self-expanding double-wire woven uncovered nitinol stent was used for intratracheal implantation and was deployed under fluoroscopic guidance. On thoracic radiography seven days after surgery, the position of the stent remained unchanged. On presentation six months after surgery, the owner reported that the dog was doing well without medical management. Although studies of various intraluminal stents have been reported in dogs, to the authors’ knowledge, use of a double-wire woven uncovered nitinol stent has not been reported previously for the management of a dog with tracheal collapse. Since this particular type of stent with unfixed individual cells provided proper airway patency without stent fracture in the dog in this report, this stent might be used as an alternative to other commercially available nitinol stents in cases of thoracic inlet collapse.
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Cherrone, Karen L., Christopher S. Eich, and Jennifer J. Bonzynski. "Suspected Paraspinal Abscess and Spinal Epidural Empyema in a Dog." Journal of the American Animal Hospital Association 38, no. 2 (March 1, 2002): 149–51. http://dx.doi.org/10.5326/0380149.

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Epidural spinal cord compression was visualized myelographically in a dog presented for rapid development of paraparesis. A large, fluid-filled pocket in the epaxial musculature was found at surgery and appeared to communicate with the first lumbar vertebra. Unfortunately, cytopathological evaluation of the fluid was not performed. No etiological agents were isolated on aerobic culture. The dog responded well to decompressive surgery and medical therapy consisting of antibiotics, pain medication, and nursing care. In the veterinary literature, only two studies of spinal epidural empyema in the dog have been reported. Of these dogs, one had successful decompressive surgery performed. The other dogs in these two reports were euthanized. The dog presented in this report fully recovered. Spinal epidural empyema should be considered as a differential diagnosis in dogs presenting with a fever and a rapidly progressing myelopathy.
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Elzein, Fatehi Elnour, Abdullah Aljaberi, Abdullah AlFiaar, and Abdullah Alghamdi. "A Large Isolated Hydatid Cyst of the Adrenal Gland: A Case Report and Review of the Literature." Case Reports in Endocrinology 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/9237903.

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A 44-year-old patient presented with two-year history of (R) lumbar pain. There was a strong history of childhood animals’ contact, including dogs. A brother had multiple hydatid cysts requiring surgery. Initial ultrasound showed a large (R) adrenal mass measuring 10×9×8 cm. Subsequent CT scan confirmed a heavily calcified cyst in the (R) adrenal gland. Hormonal studies were normal. He had an uneventful course following a total adrenalectomy. Isolated adrenal hydatid is extremely rare with an incidence of less than 0.5%; however, the diagnosis should always be suspected in all patients from an endemic area presenting with an adrenal cystic mass.
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Johnson, R. L., S. S. Cassidy, R. Grover, M. Ramanathan, A. Estrera, R. C. Reynolds, R. Epstein, and J. Schutte. "Effect of pneumonectomy on the remaining lung in dogs." Journal of Applied Physiology 70, no. 2 (February 1, 1991): 849–58. http://dx.doi.org/10.1152/jappl.1991.70.2.849.

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To determine the magnitude of functional compensation after pneumonectomy and whether compensation is related to maturity of the animal at the time of resection, we performed left pneumonectomy in either adult or 10-wk-old beagles. Studies were performed in adults 7-9 mo after surgery and in puppies 18-23 mo after surgery when the dogs reached full maturity. Results were compared with those in age- and sex-matched unoperated controls. Measurements included pressure-volume relationships, pulmonary hemodynamics, rebreathing studies of lung volume, diffusing capacity and its components, lung tissue volume, and pulmonary blood flow. Computerized-tomographic scans were performed in the puppy groups to determine changes in thoracic shape and size. Morphometric analysis of the lungs was performed under light microscopy. There was partial compensation for loss of one lung by functional improvement in the remaining lung. Compensation was greater in those pneumonectomized as puppies than as adults. Volume of the remaining lung was larger than predicted for a given transpulmonary pressure in both groups. Diffusing capacity, pulmonary capillary blood volume, and lung tissue volume were larger than expected for the normal right lung. After pneumonectomy, compliance of the rib cage was greater in puppies than in adults. Weight of the costal diaphragm was reduced in pneumonectomized puppies. Pulmonary hypertension at rest did not develop, and pulmonary vascular reactivity to hypoxia was unchanged after pneumonectomy in both groups. Significant correlations were obtained between physiological and morphometric measurements.
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Martin-Suarez, E. M., A. Galan, and J. M. Molleda. "Reincident corneal epithelial inclusion cyst in a dog: a case report." Veterinární Medicína 54, No. 2 (March 9, 2009): 84–88. http://dx.doi.org/10.17221/3003-vetmed.

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An unilateral corneal epithelial inclusion cyst (CEIC) in a 8-years-old female mixed Poodle is reported. The cyst had been observed for 60 days, was unique, not congenital and only one eye was involved. One year prior to the referral the dog was treated with antibiotics due to an ocular trauma caused by a fight with a cat. In the same eye, palpebral melanocytic tumor and corneal dystrophy were also observed. In order to remove the CEIC a superficial keratectomy was performed. Collagen contact lens and topical antibiotics were the medical treatment of choice. Fifteen month after surgery the dog was referred for recurrence of the CEIC. A second keratectomy and similar topical treatment was attempted again. A second recurrence 16 months after surgery has not been observed to the date. Cytology and histology analysis of the cyst confirmed the diagnosis of the CEIC. Microbiologic studies were also realized and <i>Staphylococcus epidermidis</i> was aisled twice in fifteen months. In this case a relapsing CEIC is reported associated to <i>S. epidermidis</i> contamination. Corneal dystrophy and palpebral melanoma were concomitant lesions, although no relations with the CEIC were concluded.
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Bimadi, Muhammad Hilman, Krisna Yuarno Phatama, and Edi Mustamsir. "Does The Peroneus Longus Tendon Autograft Affect The Ankle Function? A Case Series." Hip and Knee Journal 1, no. 1 (August 19, 2020): 57–62. http://dx.doi.org/10.46355/hipknee.v1i1.6.

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Introduction: The peroneus longus (PL) tendon is one of the autograft choices for knee ligament injury because of its safety, length, and strength. However, studies that evaluated donor site morbidity after PL tendon graft are still limited. This case series aims to evaluate the functional outcomes of donor site morbidity after full-thickness PL tendon harvesting for knee ligament reconstruction.Presentation of Case:This study evaluated four patients who had a revision of knee ligament reconstruction surgery using PL tendon autograft from August until September 2018. The functional outcome of the donor site was evaluated before surgery, two weeks, and three months after surgery by using functional scores assessment of foot and ankle.Discussion:There are some donor sites of autograft, but several studies show that the PL tendon autograft has proven to be more favorable methods for knee ligament reconstruction based on the accessibility, safety, and strength of the harvested tendon. The studies also found that using PL tendon as an autograft, has a good result in donor site morbidity evaluation compared to others. This study provides a satisfying result on the functional outcome of the donor site morbidity evaluation.Conclusion:This study showed satisfactory functional outcomes of the foot and ankle after harvesting full-thickness PL tendon. All functional score assessment provides an excellent result in three months after surgery, although lateral ankle bulging has occurred in all patients. However, gait analysis and isokinetic test with a more significant number of patients and longer follow up periods are necessary for further study.
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Dissertations / Theses on the topic "Dogs – Surgery – Case studies"

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Kongara, Kavitha. "Studies on renal safety and preventive analgesic efficacy of tramadol and parecoxib in dogs : thesis in fulfilment of the degree of Doctor of Philosophy in Veterinary Clinical Science, Institute of Veterinary Animal and Biomedical Sciences, College of Sciences, Massey University, Palmerston North, New Zealand." Massey University, 2008. http://hdl.handle.net/10179/864.

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Ovariohysterectomy and castration are common surgical procedures in small animal practice that can result in clinically significant postoperative pain. One way of controlling postoperative pain is administration of a single analgesic or a combination of different classes of analgesics prior to the onset of noxious stimuli. A constraint to the perioperative use of traditional opioids and non-steroidal anti-inflammatory drugs (NSAIDs) is their undesirable side effects. In this series of experiments, the preventive (pre-emptive) analgesic efficacy of two popular human analgesics, tramadol (an ?atypical? opioid) and parecoxib (a NSAID with selective COX-2 inhibition) was evaluated in dogs. Initially, the efficacy and renal safety of parecoxib, tramadol and a combination of parecoxib, tramadol and pindolol (a -adrenoceptor blocker and 5-HT1A/1B antagonist) were screened in anaesthetised healthy dogs. These analgesics increased the dogs? nociceptive threshold to mechanical stimuli, without causing significant alterations in the dogs? glomerular filtration rate (GFR) estimated by plasma iohexol clearance. Subsequently, the efficacy of tramadol was compared with morphine, in dogs undergoing ovariohysterectomy or castration. The Glasgow composite measure pain scale-short form score (CMPS-SF) and changes in intraoperative electroencephalogram (EEG) responses were used to assess the efficacy of analgesics. Of the three treatment groups (preoperative morphine, 0.5 mg kg-1; preoperative tramadol, 3 mg kg-1; a ?combination? of preoperative low-dose morphine, 0.1 mg kg-1, and postoperative tramadol 3 mg kg-1), dogs given the ?combination? had significantly lower pain scores after ovariohysterectomy. In castrated dogs, preoperative tramadol (3 mg kg-1) and morphine (0.5 mg kg-1) were tested and no significant difference in the CMPS-SF score were observed between them. Changes in EEG variables were not specific between the treatment groups in ovariohysterectomised dogs. Finally, the efficacy of test drugs was evaluated against acute noxious electrical stimulation in anaesthetised dogs, using EEG. Median frequency of the EEG, a reliable indicator of nociception, increased significantly in tramadol and parecoxib groups, compared to morphine, after electrical stimulation. These studies demonstrated that tramadol and parecoxib can produce analgesia in dogs with insignificant side effects. The efficacy of tramadol appears to vary with the type of noxious stimulus. A complete prevention of noxious input by administration of analgesics pre- and post-operatively could have important clinical applications.
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Ayres, Gustavo Garcia Francisco Algéos. "Meniscal injury associated with cranial cruciate ligament rupture in dogs : a retrospective case study." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2017. http://hdl.handle.net/10400.5/14654.

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Dissertação de Mestrado Integrado em Medicina Veterinária
Cranial cruciate ligament (CrCL) rupture is the most common orthopaedic disease in dogs and medial meniscal injury is very often associated with this condition. Concurrent meniscal damage can be diagnosed at the time of the stifle stabilization surgery, however, post-surgical meniscal tears can also develop and should be taken into account. This study incorporates a bibliographic review about medial meniscal tears associated with CrCL ruptures and a retrospective study of 22 stifles from 20 different dogs which were diagnosed with CrCL rupture and which meniscal integrity was evaluated. A craniomedial arthrotomy of the stifle was performed in all cases in order to diagnose meniscal damage. Meniscal tears were treated surgically in order to remove all of the damaged tissue and preserve as much healthy meniscal tissue as possible. 10 out of 22 stifles were diagnosed with concurrent meniscal injury during this study (45%). The rate of concurrent meniscal injury of this study is comparable to the previous published ones. In this retrospective study and bibliographic review it is concluded that meniscal pathology is a very common disease associated with CrCL rupture which should be treated since it causes chronic lameness, progression of osteoarthritis and pain to the patient.
RESUMO - LESÕES DE MENISCO ASSOCIADAS À ROTURA DO LIGAMENTO CRUZADO CRANIAL EM CÃES: ESTUDO DE CASOS RETROSPETIVO - A rotura do ligamento cruzado cranial (LCC) é a doença ortopédica mais comum em cães e a lesão do menisco medial é muito comumente associada a esta condição. Danos no menisco podem ser diagnosticadas aquando da cirurgia para estabilização do joelho, no entanto, lesões de menisco pós-cirúrgicas também se podem desenvolver e devem ser tidas em conta. Este estudo incorpora uma revisão bibliográfica sobre lesões de menisco associadas à rotura do LCC e um estudo retrospetivo de 22 joelhos de 20 cães diferentes aos quais foi diagnosticada a rotura do LCC e aos quais a integridade do menisco foi avaliada. Uma artrotomia craniomedial de joelho foi feita em todos os casos para diagnosticar lesões no menisco medial. As lesões identificadas foram tratadas cirurgicamente de modo a remover todo o tecido alterado e preservar tanto quanto possível o tecido saudável. Dos 22 joelhos, 10 foram diagnosticados com lesões de menisco (45%). Este valor pode ser comparável ao reportado por estudos publicados previamente. Neste estudo retrospetivo e revisão bibliográfica pode ser concluído que as lesões de menisco são uma condição associada à rotura do LCC e que deve ser tratada visto provocar claudicação crónica, dor e progressão da osteoartrite.
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Silva, Marta Mariano da. "Surgical management and outcome following adrenalectomy : a retrospective case study in 16 dogs, 2008-2018." Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2018. http://hdl.handle.net/10400.5/16057.

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Dissertação de Mestrado Integrado em Medicina Veterinária
Primary neoplasms of the adrenal gland might represent more than 1-2% of all canine tumours and can originate various worrisome clinical presentations; hence why adrenalectomy is generally the treatment of choice. Identification of prognostic factors with occasional uncertainty or contradictions among different authors renders further investigations welcomed. A retrospective study was conducted in 16 dogs undergoing adrenalectomy with the aim to describe the clinical features, surgical management and outcome. Review of clinical records and interviews with owners and veterinarians involved were performed to register clinical variables, such as, signalment, relevant history, clinical signs, laboratory, imaging and surgical findings, histopathology results, and outcome. The median survival time was calculated through Kaplan-Meier estimate. Intra- (92%) and postoperative (67%) complications, and perioperative mortality (31%) rates were comparable to recent studies; as was the median survival time (419 days), with 64% of long-term survivors living for more than 1 year, up to 3 years, approximately. This case series emphasizes that if dogs survive the immediate perioperative period, long-term outcome is generally good with possibility of prolonged survival times, as local or distant tumour recurrence appears to be low. This study also promotes awareness of adrenal incidentalomas (25%) and emergency clinical presentations (19%). Outcome predictors such as age of patients with phaeochromocytomas, size of tumour, surgeon’s experience in dealing with caval invasion, presence of metastasis at surgery, acute adrenal haemorrhage, major intraoperative haemorrhage, and postoperative disseminated intravascular coagulopathy must be considered in the approach to these cases.
RESUMO - MANEIO CIRÚRGICO E RESULTADO APÓS ADRENALECTOMIA: UM ESTUDO RETROSPETIVO DE CASOS EM 16 CÃES (2008-2018). - Neoplasias primárias das glândulas adrenais poderão representar mais do que 1-2% de todos os tumores caninos e podem originar vários quadros clínicos preocupantes; e por isso é que a adrenalectomia é geralmente o tratamento de escolha. A identificação de fatores de prognóstico com incerteza ou contradições ocasionais entre diversos autores ditam que investigações adicionais sejam bem-vindas. Um estudo retrospetivo foi conduzido em 16 cães submetidos a adrenalectomia, para descrever o quadro clínico, maneio e resultado cirúrgico. Foi feita a revisão de historiais clínicos e entrevistas a donos e veterinários envolvidos de forma a registar variáveis clínicas como identificação do animal, historial relevante, sinais clínicos, achados laboratoriais, imagiológicos e cirúrgicos, resultados de histopatologia, e resultado. A mediana dos tempos de sobrevivência foi calculada através da estimativa de Kaplan-Meier. As taxas de complicações intra- (92%) e pós-cirúrgicas (67%), e de mortalidade (31%) foram comparáveis a estudos recentes; assim como o tempo mediano de sobrevivência (419 dias), com 64% dos sobreviventes a longo prazo a viveram por mais de 1 ano, até 3 anos, aproximadamente. Esta série de casos enfatiza que se os cães sobreviverem o período peri-cirúrgico imediato, o resultado a longo prazo é geralmente bom com possibilidade de tempos de sobrevivência prolongados, uma vez também que a taxa de recorrência local ou distante aparenta ser baixa. Este estudo promove também a consciencialização de incidentalomas das adrenais (25%) e de quadros clínicos de emergência (19%). Fatores de prognóstico tais como idade dos pacientes com feocromocitomas, tamanho do tumor, experiência do cirurgião em lidar com invasão da veia cava, presença de metástases na altura da cirurgia, hemorragia aguda adrenal, hemorragia intra-cirúrgica de maior importância, e coagulopatia intravascular disseminada pós-cirúrgica, devem ser considerados na abordagem a estes casos.
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Leung, Wai-Ching. "Equity of access to health care : case studies in primary care and coronary artery surgery." Thesis, University of East Anglia, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.249587.

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Equity of access to health care was the founding aim of the NHS and a recent White Paper on NHS reforms re-emphasised its importance. This thesis consists of two contrasting studies on equity of access using individual patients as units of analysis. The main objective of the first study was to examine the equity of access to primary care services including GP consultation, out-of-hour services and referral to specialist services. The study involved secondary analysis of patient questionnaire data from a national survey. The objectives of the second study were to examine the equity of access to coronary artery surgery in one health district among those who underwent coronary angiography, and to examine whether the waiting time for coronary artery surgery was correlated with clinical need. It involved retrospective collection of data from medical records using the New Zealand Priority scores as an indicator of need. The first study showed that the following patient groups subjectively experienced disadvantages in several aspects of primary care services:- younger people, those with poor subjective physical and mental health, females, non-whites, residents in Inner London and those in paid work or full-time education. The possible reasons for these findings were discussed. It was recommended that the delivery of primary care services should take into account these results and that further research should be conducted into the extent and nature of differential patient expectation amongst different patient groups. The second study did not show any significant inequity of access to coronary artery surgery according to sex, age, smoking status and socio-economic status. However, there was little correlation between clinical need and waiting time for coronary artery surgery. These results informed subsequent development of cardiology and cardiac surgery services in the health district. The methodologies used in these two studies were compared and contrasted.
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Jarman, Lisa Charlotte. "Galen in Early Modern English medicine : case-studies in history, pharmacology and surgery 1618-1794." Thesis, University of Exeter, 2013. http://hdl.handle.net/10871/15279.

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This thesis examines the influence of Galen (b. 129 AD) on medicine in England between 1618 and 1794, approaching the study of his authority and the use of his work through three case-studies: histories of medicine, pharmacology, and surgery. The histories of medicine illustrate the variety of ways in which Galen is referred to, both as a historical figure, and as an ongoing contemporary influence. His importance in terms of accessing the knowledge of the ancients, and as a fixed point in time around which to discuss the history of medicine, and to situate other practitioners over a broad time period, underlines the significance of his role within medicine. Similarly, the pharmacological texts examined provide a more tangible sense of the influence of Galen, and their varied, but formulaic structures enable specific remedies to be traced over time and their corresponding associations and details compared between different editions. Identifying the role of Galen within surgical treatises also allows for a more theoretical aspect of surgery to be explored, providing a different perspective on an area more frequently portrayed as a manual art. The use of Galenic texts within each case-study, in particular the histories of medicine, demonstrates a significant and nuanced engagement with the content of his works, reiterating the importance of his contribution, and showing the value ascribed to the simplicity offered by past approaches. It is evident that a shift had occurred from the acceptance of ancient authority based on convention, to evaluating the simplicity and utility of information on an individual basis. The value ascribed to utility in the assessment of medical knowledge is evident throughout these texts, which also demonstrate the importance of the experience and observations of the practitioner in facilitating the ongoing and significant use of the influence of Galen.
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Lem, Kristina Yvonne. "Evaluation of dietary factors associated with spontaneous pancreatitis in dogs." [College Station, Tex. : Texas A&M University, 2007. http://hdl.handle.net/1969.1/ETD-TAMU-1504.

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Fowler, Lori Ann. "Breast implants for graduation? Parent and adolescent narratives." Thesis, University of North Texas, 2008. https://digital.library.unt.edu/ark:/67531/metadc6111/.

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The purpose of this research is to examine through sociological and psychological theories how women make sense of the desire and attainment of breast implants for graduation. The study used a qualitative approach and focused on women ages 18-35 in the state of Texas who have received breast implants for graduation. The sample size in this study included 10 high-school graduates receiving implants as a gift and their 10 mothers. Seven theoretical paradigms provided a better understanding for why the daughters asked for breast implants and why the parent(s) paid for them. Symbolic interaction theory explained why the daughters wished to replace their "fake" cotton padded self with their augmented self, to become the most authentic woman possible. Social construction of reality theory explained why both mothers and daughters wanted to conform to the social construction of gender, and to accomplish their gender well. Conspicuous consumption theory demonstrated how cosmetic surgery practices allow women to appear wealthy, gain status, and "flash" their assets. Feminist theory explained why some women were motivated to capture the attention of men and others altered the body out of empowerment. Reference group and social comparison theories explained how the women in this study were influenced to undergo cosmetic surgery by ranking themselves in attractiveness against real friends and media icons. Lastly, self-discrepancy theory showed how the daughters in this study felt they needed surgery to fix a discrepancy between their real and ideal self. The majority of respondents expressed complete comfort with their gifting and receiving of breast implants for graduation, claiming it was a great decision. They also agreed surgery was worth any risk to increase their daughter's confidence. Most of the mothers expressed that they were comfortable with their decision to gift surgery to their daughters, despite knowing that their gift of augmentation would ultimately result in more surgery in the future.
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Fradique, António Amável Caldeira. "Mecanismos biopatológicos da metastização ganglionar no carcinoma gástrico. Implicações para a cirurgia radical." Doctoral thesis, Faculdade de Ciências Médicas. Universidade Nova de Lisboa, 2009. http://hdl.handle.net/10362/5100.

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RESUMO A constatação de que o carcinoma gástrico continua a ser a segunda causa de morte por doença oncológica no mundo em geral e em particular em Portugal, assim como a verificação da elevada incidência e letalidade no nosso país, justifica uma particular atenção a esta doença. Apesar de avanços recentes na acção adjuvante e neo-adjuvante de terapêuticas não cirúrgicas, com algumas referências a melhorias na sobrevivência, estas terapêuticas não têm eficácia curativa. Sendo assim, a cirurgia continua a constituir a única esperança de cura no carcinoma gástrico. Em consequência, a correcta selecção da técnica a aplicar, assim como a sua correcta execução, vão ter influência marcante na sobrevivência do doente. Os estudos dos centros oncológicos diferenciados em várias zonas geográficas demonstram que a cirurgia radical, com adequada extensão da gastrectomia e com linfadenectomia alargada permite obter as melhores sobrevivências. O tipo de cirurgia mais praticado nos referidos centros oncológicos diferenciados é a gastrectomia com linfadenectomia D2, ou seja, com excisão da segunda estação ganglionar. Este tipo de cirurgia não aumenta a mortalidade, mas aumenta a morbilidade. No entanto, verifica-se que muitos doentes não desenvolvem metastização que atinja a estação ganglionar de nível 2 e, por outro lado, muitos outros ultrapassam esta estação ganglionar. Ou seja, a linfadenectomia D2 é exagerada para alguns doentes, é necessária e suficiente para muitos, mas pelo contrário, é insuficiente para outros. A questão radica na necessidade de equilíbrio em oferecer a cada doente a cirurgia necessária para obter a melhor sobrevivência, ainda que à custa de maior morbilidade e, por outro lado, conseguir identificar os factores que determinam que alguns doentes não necessitem de ser submetidos a uma terapêutica tão agressiva. Se a primeira questão é eminentemente fisiopatológica e consiste em compreender os mecanismos da metastização ganglionar no carcinoma gástrico, de modo a poder prever a incidência e extensão da metastização ganglionar em cada doente em particular e, assim, adequar a terapêutica. No estudo de 50 doentes, que elaborámos, a interpretação fisiopatológica apoia-se na avaliação de parâmetros aceites como convencionais e de parâmetros oncológicos. Dentro dos parâmetros convencionais estudámos a localização do tumor, a sua dimensão, a classificação de Borrmann, as alterações metabólicas, a gastrina sérica, a citologia peritoneal, a infecção pelo Helicobacter pylori (Hp), a metaplasia intestinal, a classificação de Ming, a classificação de Lauren, a invasão em profundidade da parede gástrica (T), a metastização no “early gastric câncer”, a classificação TNM, o CEA 19.9 e o CA 72.4 séricos. Para identificar quais os marcadores oncobiológicos mais adequados, efectuámos uma revisão da literatura relativamente a: Ki-67, p53, caderina-E, ERBB2, Instabilidade de Microssatélites, MUC 1, Sialil Tn e Sialil Lewis X. De acordo com os resultados referidos na literatura, seleccionámos para estudo os seguintes marcadores: Ki-67, p53, caderina-E, ERBB2 e Instabilidade de Microssatélites. Relacionámos todos estes parâmetros com a metastização ganglionar, nos aspectos de frequência da metastização, número de gânglios metastizados (classificação N da UICC) e metastização das cadeias ganglionares distais (classificação N japonesa). No que se refere à execução do programa cirúrgico, foram obtidos níveis de radicalidade semelhantes ou superiores aos referidos na literatura internacional, com frequência de complicações ao nível da referida na literatura europeia. No que se refere ao estudo dos factores de metastização ganglionar verificámos que os parâmetros que apresentam maior relação com a frequência da metastização são: a dimensão ≥ 5 cm; a profundidade de invasão da parede (T) atingindo as camadas profundas; o tipo infiltrativo na classificação de Borrmann; a expressão de Ki-67 > 75%; a expressão de p53 positiva; a expressão de caderina-E anormal; a associação de Ki-67 ≥ 50% + caderina-E anormal + p53 positiva; a associação de dimensão ≥ 5 cm + p53 positiva; a associação de T3/T4 + p53 positiva; a presença de marcadores tumorais elevados. A ausência de metastização ganglionar ou metastização limitada à primeira estação ganglionar, em que é suficiente uma cirurgia conservadora de tipo D1, relaciona-se com a dimensão < 5 cm; a invasão em profundidade da parede (T) limitada às camadas superficiais; a ausência de expressão de p53; a ausência de níveis elevados de marcadores tumorais. Recorrendo ao estudo dos quatro parâmetros que podem ser determinados no pré-operatório – dimensão, invasão em profundidade, expressão de p53 e marcadores tumorais convencionais foi possível identificar 75% dos tumores N0 e 50% do conjunto dos tumores N0 + N1, ou seja, os tumores que não carecem de linfadenectomia alargada. Estudando a dimensão, a presença de Hp, a invasão em profundidade, os níveis elevados de marcadores tumorais, a expressão de p53, Ki-67, de Caderina-E e de Instabilidade de Microssatélites foi possível caracterizar os tumores que envolvem maior risco de invadir as cadeias ganglionares distais e que, portanto, carecem de linfadenectomia alargada. Verifica-se assim que, com esta metodologia, é possível identificar uma percentagem significativa dos casos que não carecem de linfadenectomia alargada assim como daqueles que necessitam deste tipo de cirurgia.
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Lidman, Linda. "Kvalitet-i-Bruk för Beslutstödssystem inom Thoraxkirurgi." Thesis, Linköping University, Department of Computer and Information Science, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1284.

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The aims of the practical work carried out for this thesis were to redesign a clinical decision support system for thoracic surgeons, called AssistMe, and to evaluate the concept behind this system. The main objective of the thesis is to give an account of the considerations that were found to be of key importance for designing a clinical decision support system for thoracic surgery. Another aim was to let future users test the system after it had been redesigned and evaluate the concept behind it. The thesis also investigates users’ experience of the system and their views on whether it would be applicable in their daily work practice. An account is also given of experience of using QOC-notation during the design space analysis in a real design project like this one.

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Muñante, Cardenas Jose Luis. "Traumatismos faciais em pacientes pediatricos e adolescentes = analise epidemiologica." [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/289449.

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Orientador: Jose Ricardo de Albuquerque Barbosa
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologika
Made available in DSpace on 2018-08-15T11:26:22Z (GMT). No. of bitstreams: 1 MunanteCardenas_JoseLuis_M.pdf: 1001514 bytes, checksum: 4dea799fe4c80806263615b573dd2c89 (MD5) Previous issue date: 2010
Resumo: Realizamos um estudo retrospectivo para analisar as diferentes características das fraturas faciais na população pediátrica atendida pela Área de Cirurgia Buco-Maxilo-facial da Faculdade de Odontologia de Piracicaba -UNICAMP entre 1999 e 2008. Foram analisados os prontuários de 2986 pacientes, dos quais 757 foram menores que 18 anos. Os seguintes parâmetros foram avaliados: idade, sexo, etiologia, localização e tipo de fratura, lesões associadas, tratamento e complicações. Resultados: Foram atendidos 530 crianças e adolescentes de gênero masculino (70,01%) e 227 do gênero feminino (29,99%), sendo os adolescentes o grupo etário mais afetado. As causas mais comuns das lesões foram os acidentes de bicicleta (220, 29,06%) e as quedas (215, 28,40%). O osso facial mais afetado por fraturas foi a mandíbula (112, 44,8%) e as lesões associadas mais freqüentes foram as lacerações e o trauma dentoalveolar. O tratamento foi cirúrgico em 75 casos (30%) e as principais complicações foram deiscência, hemorragia pósoperatória e infecção de material de fixação interna. Conclusões: Os acidentes de bicicleta e as quedas foram consideradas as principais causas de injurias maxilo-faciais. A mandíbula foi a mais afetada por fraturas. Estudos epidemiológicos de lesões faciais permitem o desenho das circunstâncias de risco e a identificação dos indivíduos mais sucetiveis. A avaliação da eficácia do tratamento instituído e a compreensão de suas complicações permite uma interpretação realista e coerente da melhor forma como estes doentes devem ser conduzidos.
Abstract: We performed a retrospective study to analyse the different characteristics of such fractures in the pediatric population of Piracicaba Region, Sao Paulo, Brazil. We reviewed the clinical records of 2986 patients. A total of 757 patients under 18 years were treated by the Oral and Maxillofacial Surgery Division of Piracicaba Dental School between 1999 and 2008.The following parameters were evaluated: age, sex, etiology, location and type of fracture, associated injury, treatment and complications. Results: There were 530 boys (70.01%) and 227 girls (29.99%), treated for injuries, with the main prevalence in teenage. The most common injury causes were bicycle accidents (220, 29.06%) followed by falls (215, 28.40%).The facial bone most affected by fractures was the mandible (112, 44.8%) and the associated injuries were lacerations, dentoalveolar trauma and craniofacial trauma. The treatment was surgical in 75 cases (30%) of cases and the main complications were dehiscence, post-operative infection and loosed of internal fixation material and facial paraesthesia. Conclusions: Bicycle accidents and falls were found to be the principal causes of maxillofacial injuries. The facial bone most affected by fractures was the mandible. Epidemiological studies of facial injuries enable the design of the risk circumstances and the identification of the most vulnerable individuals. The evaluation of the effectiveness of treatment instituted and understanding its complications allow a realistic and consistent interpretation about which is the best way for treating these patients.
Mestrado
Cirurgia e Traumatologia Buco-Maxilo-Faciais
Mestre em Clínica Odontológica
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Books on the topic "Dogs – Surgery – Case studies"

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Lippincott, Charles L. A practical guide for small animal surgery. Pico Rivera, Calif: Southern California Veterinary Medical Association, 1988.

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P, Armstrong C., and Carroll R. N. P, eds. Case presentations in general surgery. London: Butterworths, 1987.

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Cuesta, Miguel A., and H. Jaap Bonjer, eds. Case Studies of Postoperative Complications after Digestive Surgery. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-01613-9.

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Kim, Sandra I. Surgery. 4th ed. Philadelphia: Lippincott Williams & Wilkins, 2007.

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E, Watson Christopher J., ed. Surgery: Clinical cases uncovered. Malden, Mass: Blackwell Pub., 2008.

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Herrman, John B. Case studies in general surgery: Problem-based surgical education. Baltimore: Williams & Wilkins, 1988.

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Barr, Lester C. 100 case histories for the FRCS. Edinburgh: Churchill Livingstone, 1989.

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Clinical scenarios in general surgery. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, 2013.

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H, Savoie Felix, ed. MasterCases: Shoulder and elbow surgery. New York: Thieme, 2003.

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Fenn, Donna. Alpha Dogs. New York: HarperCollins, 2009.

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Book chapters on the topic "Dogs – Surgery – Case studies"

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Jing, Zaiping, Huajuan Mao, Meiqin Shi, Junmin Bao, Zhiyong Chen, Yifei Pei, Xiaolong Wei, et al. "Case Studies." In Endovascular Surgery and Devices, 177–238. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-8270-2_19.

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Miller, Kai J., and Elaine Wirrell. "Disconnection Surgery." In Epilepsy Case Studies, 253–58. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-59078-9_45.

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Thoma, Achilles, Jenny Santos, Jessica Murphy, Eric K. Duku, and Charles H. Goldsmith. "Case-Control Studies." In Evidence-Based Surgery, 171–81. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-05120-4_17.

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Grewal, Sanjeet S., Diogo M. Garcia, Erik H. Middlebrooks, and Robert E. Wharen. "Minimally Invasive Surgery." In Epilepsy Case Studies, 247–51. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-59078-9_44.

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Tatum, William O. "Surgery Candidate (Scalp EEG)." In Epilepsy Case Studies, 139–43. Cham: Springer International Publishing, 2013. http://dx.doi.org/10.1007/978-3-319-01366-4_31.

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Tatum, William O. "Surgery Candidate (Intracranial EEG)." In Epilepsy Case Studies, 145–49. Cham: Springer International Publishing, 2013. http://dx.doi.org/10.1007/978-3-319-01366-4_32.

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Pinnock, Gail, and Mary O'Kane. "Bariatric surgery." In Dietetic and Nutrition Case Studies, 136–39. Chichester, UK: John Wiley & Sons, Ltd, 2016. http://dx.doi.org/10.1002/9781119163411.ch35.

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Van Gompel, Jamie J., and Gregory D. Cascino. "Epilepsy Surgery: Intracranial EEG (iEEG) Candidate." In Epilepsy Case Studies, 235–39. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-59078-9_42.

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Holtkamp, Martin. "Novel Seizure Semiology After Epilepsy Surgery." In Neuropsychiatry Case Studies, 115–19. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-42190-2_20.

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Sabsevitz, David, and Karen Blackmon. "Neuropsychological Assessment in Temporal Lobe Epilepsy Surgery." In Epilepsy Case Studies, 167–72. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-59078-9_30.

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Conference papers on the topic "Dogs – Surgery – Case studies"

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Apitz Castro, R., E. Ledezma, A. Jorquera, and M. K. Jain. "REVERSIBLE BLOCKADE OF PLATELET ACTIVATION DURING CARDIO-PUIMONAR BYPASS IN DOGS AFTER IV ADMINISTRATION OF AJOENE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644820.

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Surgery with extracorporeal circulation (ECC) is associated with platelet activation, which greatly contribute to prolonged postoperative bleeding and increased blood loss after surgery. Antiplatelet ccnpounds which induce rapid and reversible inhibition of platelet function, without affecting platelet adhesiveness would be potentially useful in the management of the platelet-dependent hemostatic disorder observed in ECC. Ajoene, an organosulfur originally obtained from garlic, inhibits platelet release and aggregation induced ex vivo by all know agonists. It does not affect shape change or adhesion to collagen nor interfere with metabolic pathways relevant to the platelet reaction. Ajoene action is related to its direct interaction with the fibrinogen receptor on the platelet surface which irrpairs fibrinogen binding to stimulated or chymotrypsin treated platelets. IV administration of ajoene (15 mg/Kg) to mongrel dogs, inhibits platelet aggregation induced ex vivo by collagen (2-5 g/ml) or ADP (10 M). Ccnplete inhibition is attained after 20-35min and recuperation of platelet reactivity is obtained after 2.5-3.5 hours. To study the potential benefit of ajoene for the prevention of platelet activation during cardio-pulnonary bypass, ajoene was administered to anesthesized (heparin-anticoagulated) dogs, as described above, 40min before establishing the ECC. Circulation was mantained at 1.5L/min for a period of lOOmin Platelet count, and aggregation induced esc vivo by ADP or collagen were meassured immediately before ajoene administration, lOmin after the end of ECC and thereafter, hourly. Platelet count lOmin after end of ECC, in ncn-treated dogs fell to about 57% of prepump values, while in ajoene-treated animals circulating platelets represented 80% of pre-ECC values. Recovery of platelet function in ajoene-treated dogs started 2 hr after end of ECC (about 4 hr. after ajoene administration) reaching 70% 4 hr after end of ECC. Surgical bleeding in treated-dogs was not different frrm controls. Moderate bradicardia and hypotension, which in atrqpi-nized dogs returned to normal values within 3 min was observed. Although detailed pharmacological studies are still needed, our results suggest that ajoene is a potentially useful drug for the prevention of platelet activation induced by ECC.
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Jallah, Zegbeh C., Laura Skoczylas, Suzan Stein, Naoki Yoshimura, Pamela Moalli, and Steven D. Abramowitch. "Maternal Childbirth Injury Alters Vaginal Smooth Muscle Contractility." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53798.

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Pelvic organ prolapse (POP) is a multifactorial disorder, characterized by the descent of the pelvic organs into the vaginal canal. POP is associated with decreased quality of life, and even depression, yet 50% of women over the age of fifty are living with this disorder. The estimated direct cost for POP surgeries is over one billion dollars annually, in the United States alone. This rather exorbitant figure includes the cost of surgery performed for symptom management, but does not include strategies which address the underlying cause of the disorder. It is not surprising then, that within a few years over 10% of repairs will require a second procedure. Thus, more studies are needed to understand the pathophysiology of POP.
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Gorski, Dmitri, Martin Kvernland, Knut Hals, Margrethe Blaaflat, Johannes Ladenhauf, Ole Morten Aamo, and Sigbjørn Sangesland. "Determination of Dynamic Limits for Rig Heave and Running Speed Based on Drilling Parameters, Well Data and Completion Tool Limitations - Case Studies." In SPE/IADC International Drilling Conference and Exhibition. SPE, 2021. http://dx.doi.org/10.2118/204023-ms.

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Summary A novel method of utilizing simulations of surge and swab induced by floating rig heave is presented in this paper. The intended applications are in well planning and follow-up of drilling and completion operations. We focus on rig heave during drill pipe connections when the rig's heave compensator cannot be engaged. The method consists of: (1) estimating a dynamic, well- and operation-specific, rig heave limit based on surge & swab simulations at different depths in a well and (2) clearly communicating the dynamic rig heave limit to the rig crew and onshore organization as a simple metric. We present cases where this novel methodology has been tested during the drilling and completion of two offshore wells in Norway, and we elaborate on the operators’ view of the method's advantages. We conclude that complementing the traditional fixed rig-specific heave limit with the dynamic one that is based on the properties of the actual well and the actual drilling/completion parameters offers an opportunity to improve management of risks related to breaching well pressure margins or damaging downhole equipment and to reduce costs through reduction of weather-related non-productive time. We show that the dynamic rig heave limit may differ significantly from well to well and also throughout the same well depending on the kind of operation in the well, depth in the well, well geometry and other parameters related to well and operation properties. Our conclusion is that care should be taken when generalizing a maximum allowed rig heave value as is the industry practice today. The benefits of utilizing dynamic well-specific rig heave limit should be assessed during well planning for any well drilled and completed from a floating rig. Well planning software existing today does not offer this functionality.
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Modica, F., C. Pagano, V. Marrocco, and I. Fassi. "Micro-EDM Studies of the Fabrication of Customized Internal Fixation Devices for Orthopedic Surgery." In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-46489.

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The fabrication of personalized implants, tailored on patient needs, is a key issue for the future of several surgical fields. The presence of a prototyping service inside the hospital would be an added value for improving clinical activity. In this context, micro-Electro Discharge Machining is exploited to customize fixation devices in orthopedic surgery. An overview of the main devices is carried out in order to identify the main characteristics and to define the common fixation system specifications. The experimentation includes a technological evaluation of the proper micro-EDM technology, chosen according to the final design of the components. Two materials are investigated for the device fabrication: titanium and Si3N4-TiN ceramic composite. An optimization of the main technological parameters is performed in order to maximize the material removal rate ensuring the accuracy of the micro-features required. Finally, a test case is selected in order to evaluate the entire fabrication process chain.
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Kabalyk, Kirill, Grzegorz Liśkiewicz, Longin Horodko, Władysław Kryłłowicz, and Matthew Stickland. "Use of Pressure Spectral Maps for Analysis of Influence of the Plenum Volume on the Surge in Centrifugal Blower." In ASME Turbo Expo 2014: Turbine Technical Conference and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/gt2014-26931.

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The influence of plenum volume on surge phenomenon in a centrifugal blower was studied by means of quasi-dynamic analysis. In this procedure, signals were gathered at 5 pressure tappings at 146 different positions of the throttling valve controlling the mass flow rate. Frequency spectra obtained by means of Fourier analysis are combined together in the form of colour maps with frequency as the abscissa and valve position as the ordinate. Such a map provides high-resolution information about spectral structures of pressure signals attained at different mass flow rates. Analysis was conducted at two system configurations characterized by different volumes between the blower and the valve i.e. plenum volume. Research confirmed that in both cases the first disturbances appear in the vicinity of the impeller leading edge in the same position of a throttling valve before the surge. Arising flow structure is characterized by strong and random pressure jumps and does not have any dominating frequency. At further valve closure pressure disturbances propagate towards the volute and at deep surge the strongest peaks are observed at the outlet. The moment of deep surge onset is also independent of the plenum volume, however, a difference is observed in the frequency and amplitude of the main modes. With the higher outlet volume the observed oscillations fit well to the frequency of a Helmholtz resonator while, in the case of the smaller volume, the frequency is higher than the frequency of a corresponding Helmholtz resonator.
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Eriksson, E., and B. Risberg. "CAN THE RESPIRATORY PATTERN INFLUENCE FIBRINOLYSIS ?" In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643124.

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Pulmonary endothelium produce large amounts of tissue plasminogen activators (t-PA) and presumably activator inhibitors (PAI). Any systemic role of this pulmonary production is unknown. Previous studies in dogs have demonstrated that respiratory pattern influenced the fibrinolytic activity in blood. Plasminogen activators were thought to be released from lungs. Too study if similar conditions existed in man we evaluated the fibrinolytic response in surgical patients during various pattern of mechanical ventilation. Twelve patients undergoing infrarenal aortic reconstruction were evaluated. Blood samples were taken from the pulmonary artery and a radial artery before and at various times during surgery. Mechanical ventilation with varied levels of PEEP (0, 5, 10 and 15 cm H2O) was used. Samples were taken in ice-cooled EDTA vacutainers and the blood was centrifuged at 8000 g for 2 min. Plasma was frozen at −70° C for later analysis. Fibrinolytic activity was monitored by analysis of ECLT, t-PA activity, t-PA antigen (ELISA) and PAI activity. During surgery ECLT and t-PA activity were below detectable levels. t-PA antigen was at baseline 9-18 ng/ml and increased transiently early during surgery with 3.9 ± 1..0 ng/ml in the radial artery and 3.2 ± 1.9 ng/ml in the pulmonary artery (mean ± SEM). PAI was at baseline 2.0 - 35.2 IU. During surgery it increased significantly with 43.6 ± 8.6 IU/ml in the radial artery and 36.9 ± 9.6 IU/ml (mean ± SEM). There were nc gradients over the lung in either t-PA antigen or PAI. PEEP at levels from 0-15 cm H2O did not affect the measured parameters. Thus, during surgery there was a transient increase in t-PA antigen and a progressive increase in PAI, both pulmonary independent. The respiratory pattern did not influence the fibrinolytic system and could unlikely be an important factor in resolution of pulmonary emboli.
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7

Jain, Vandana, Rupinder Sekhon, Shveta Giri, and Sudhir Rawal. "R-veil in carcinoma vulva." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685390.

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Background: Vulvar cancer accounts for about 3-5% of gynaecologic malignancies. Prognosis is strongly dependent on presence of inguinofemoral lymph node metastases. Effective management of regional lymph nodes is the most important factor in the curative management of early vulvar cancer. Despite careful dissection and maintaining vascularity of skin, surgical morbidity is seen in 50% cases. Video – endoscopic inguinofemoral lymphadenectomy was developed by Bishoff in 2003 by dissecting two cadaveric models and in one patient with stage T3N1M0 penile carcinoma. VEIL is an alternative to reduce the morbidity without compromising the oncologic outcomes. VEIL has continued to evolve into single site and robotic variants. R-VEIL is a minimally invasive procedure duplicating the standard open procedure with less morbidity. Aims and Objectives: A video presentation to describe the technique of R-VEIL in vulvar cancer and discuss the advantages and outcome. Conclusions: R–VEIL is an attractive minimally invasive technique to do inguinal block dissection in a single sitting in patients with vulvar carcinoma as the surgeon does not get tired as happens in VEIL technique. R-VEIL allows the removal of inguinal lymph nodes within the same limits as in open procedure and potentially reduces surgical morbidity. It is better accepted cosmetically and reduces hospital stay. Long term oncological results are not available. Randomized multi-institutional studies are required to prove its efficacy over open counterpart.
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Jain, Vandana, Rupinder Sekhon, Shveta Giri, and Sudhir Rawal. "R-VEIL in carcinoma vulva." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685393.

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Background: Vulvar cancer accounts for about 3-5% of gynaecologic malignancies. Prognosis is strongly dependent on presence of inguinofemoral lymph node metastases. Effective management of regional lymph nodes is the most important factor in the curative management of early vulvar cancer. Despite careful dissection and maintaining vascularity of skin, surgical morbidity is seen in 50% cases. Video – endoscopic inguinofemoral lymphadenectomy was developed by Bishoff in 2003 by dissecting two cadaveric models and in one patient with stage T3N1M0 penile carcinoma. VEIL is an alternative to reduce the morbidity without compromising the oncologic outcomes. VEIL has continued to evolve into single site and robotic variants. R-VEIL is a minimally invasive procedure duplicating the standard open procedure with less morbidity. Aims and Objectives: A video presentation to describe the technique of R-VEIL in vulvar cancer and discuss the advantages and outcome. Conclusions: R – VEIL is an attractive minimally invasive technique to do inguinal block dissection in a single sitting in patients with vulvar carcinoma as the surgeon does not get tired as happens in VEIL technique. R-VEIL allows the removal of inguinal lymph nodes within the same limits as in open procedure and potentially reduces surgical morbidity. It is better accepted cosmetically and reduces hospital stay. Long term oncological results are not available. Randomized multi-institutional studies are required to prove its efficacy over open counterpart.
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de la Torre, Roger A., and Jaya Ghosh. "Device for Safely Closing Trocar Sites in Minimally Invasive Abdominal Surgery." In 2017 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/dmd2017-3399.

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Abstract:
Laparoscopic and robotic surgeries of the abdomen require a trocar to facilitate entry and removal of instrumentation. Some of these trocars are 5mm or less, but some trocars for these surgeries are larger, with 8mm to 15mm trocars commonly used. One of the well-known problems seen in minimally invasive surgery to the abdomen is the resulting defect left in the abdominal wall following removal of the trocars. Occasionally, especially after removal of larger trocars, a defect is left that is large enough to allow omentum or segments of small intestine to become entrapped within the resulting space in the abdominal wall. These trocar site hernias can cause pain, but they also may lead to small bowel obstruction and bowel ischemia or even infarction, perforation and death. The likelihood of a trocar site hernia is increased when the minimally invasive procedure requires removal of an organ or a mass. This often requires dilatation of the trocar site opening.1,2,3 Re-operation to reduce and repair trocar site hernias adds significant cost to the healthcare system. Two separate studies report that incidence of trocar site hernias are in the ranges of 0.65%–2.8%4 and 1.5%–1.8%5,6. Based on a 2016 report published by the American Society for Metabolic and Bariatric Surgery (ASMBS), 196,0007 bariatric procedures were performed in 2015. Assuming an average incidence rate of 1.7%, and based on the cost analysis provided by a 2008 case study8, in bariatric surgery alone, it is estimated that the treatment and hospitalization of such hernias adds an additional $86.2M to healthcare costs. Several methods and devices exist to prevent the occurrence of trocar site hernias. However, closing superficial fascia externally is difficult, especially in obese patients, and often requires extending the skin incision significantly. Most instruments to close the potential hernia site involve introducing a hollow needle with a built-in, grasping device through tissue on one side of the defect and into the abdominal cavity. This puts internal structures at risk for potential injury. One end of suture is introduced with this needle and then using a separate instrument through a different trocar this suture is held while the needle is removed. The needle device is then re-introduced through tissue on the opposite side of the defect, and the suture is handed back to the needle device and pulled out completing a U-stitch to close the potential hernia site. If a surgeon inserts a finger into the abdomen along the trocar site to guide the needle, there is the potential for injury to the surgeon’s finger. Therefore, we set about to design a device to close trocar site defects that would work efficiently, while being safe from injury to the patient or the surgeon, and preferably without the need for a separate instrument through a different trocar to assist.
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10

Julian, D. G. "UNSTABLE ANGINA : DEFINITION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643709.

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Abstract:
A satisfactory definition of unstable angina continues to be elusive.Like stable angina, it is a clinicalsyndrome, and mustbe defined in those terms. In both cases, it is understood that myocardial ischaemiabut not infarction is responsible for the symptoms. For angina to earn the “unstable” label, theremust have been the recent development or deterioration of symptoms. Traditionally, “recent” has meant within the last month, but it has become increasingly clear thatthe time frame is of critical importance - the patient with a sudden irruption of severe chest pain in the last two days is likely to have a different pathology and prognosis from the individual who first developed exercise-induced pain two weeks ago, which has not worsened during this period. Likewise, the patient who hadhis last attack of pain one week agois very different from one who had his last attack one hour ago; indeed in the HINT study, there was a high incidence of myocardial infarction undetected on admission in the lattergroup (Br Heart J 1986;56:400-13).A problem that has hardly been addressed is “When does unstable angina stop being unstable?”. The answer must be when it either becomes stable (i.e. stops getting worse),or proceeds to myocardial infarctionor death.Most studies have shown that the vast majority of patients stablise quickly, often losing their symptoms completely. There is, however, a group of patients who fail to respond promptly to medical treatment, and it isthese patients who are most likely to go on to angiography, angioscopy, angioplasty, surgery, myocardial infarction or death. Thus, the enormously valuable information we have obtained from, for example, angiography and necropsy studies applies essentially only to this subset of unstableangina patients, albeit they are themost severe. Unfortunately, such studies tell us relatively little aboutthe more dynamic aspects of the disorder, such as the role of coronary vasomotion.It is only relatively recently that clinicians have appreciated that they have quite simple means of suspecting the mechanisms involved. Thus, the history of progressive exercise-induced angina on the one hand or angina only at rest on theother must tell us something of the underlying physiopathology. Likewise,the fact that the symptoms respond to rest, or beta-blockers, or calcium antagonists also provides evidenceas to causation.Thus, while all would agree that angina is “unstable” whenit has recently developed or worsened, it must bediscussed in subsetsdefined by their history and response to treatment.In this way, we may be able to assign a patient to a particular clinicalgroup, which will indicate that it is likely that he has a particular physiopathology, which inturn will suggest the most appropriate management.
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