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1

Kumar, Dr Amit, Dr Jayanti Jain, Dr Ritu Kapoor, and Dr Manoj Adlakha. "A Critical Review of Charakokta Vishghana Mahakashaya as Antioxidant in Present Scenario." International Journal for Research in Applied Science and Engineering Technology 10, no. 10 (2022): 1180–85. http://dx.doi.org/10.22214/ijraset.2022.47152.

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Abstract: Visha is another name for a chemical that depresses society. Visha is a material that is harmful to life and has properties like Aniedeshyarasa/Apaki, Vyavayi, Vikasi, Ushna, Teekshna, Ruksha, And Asukar. Garavisha is the name for synthetic poison, krutrima visha. These Gara vishas, depending on their combinations. Gara vishas, depending on their combinations, can cause illnesses like Shopha (edoema), Pandu (anaemia), Udara (ascites), Unmada (psychological disturbance), Durnam (piles), etc. in the body. Dooshivisha is the term for Sthavara, Jangama, or Krutrima poisons that are not c
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2

P, Deepa, Nataraj H R, Prajwal H N, and Anushree C G. "Standardization of Dooshivishahari Agada through HPTLC." International Journal of Ayurvedic Medicine 13, no. 2 (2022): 479–82. http://dx.doi.org/10.47552/ijam.v13i2.2413.

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Ayurveda medicines are a time-tested and valuable resource for healing, even today, globally. Hence the quality control standards for the Ayurvedic formulations is the need of time because of commercialization. Despite the availability of modern equipment and techniques, not all Ayurvedic formulations have been standardized as per modern day protocol. Dooshivishari agada (DVA), a herbo-mineral preparation; mentioned in the text of Asthangha hrudaya in the context of treatment of poisoning, specifically for dooshivisha (cumulative poison). High-performance thin-layer chromatography (HPTLC) is a
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3

Singh, Vishal, T. Sangeeta, and Mohamed Muzzammel. "Bridging ancient wisdom and modern insights: Understanding cancer through the lens of Dooshivisha and environmental toxicology." Ayush Journal of Integrative Oncology 1, no. 3 & 4 (2024): 46–53. https://doi.org/10.4103/ajio.ajio_14_24.

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The concept of Dooshivisha in Ayurveda, which refers to the accumulation of latent toxins in the body over time, provides a valuable framework for understanding the onset of chronic diseases such as cancer. This idea aligns closely with modern scientific findings on how environmental toxins, such as pesticide residues and persistent organic pollutants, accumulate in the human body and contribute to long-term health issues. Research shows that exposure to carcinogenic chemicals, particularly in early life through breastfeeding, significantly increases cancer risk. Similarly, lifestyle factors s
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4

A V, Smitha, Maya Mohan A, and Shitha N R. "Study on Palmo Plantar Psoriasis with special reference to Vipadika: A Case Report." International Journal of AYUSH Case Reports 9, no. 1 (2025): 39–48. https://doi.org/10.70805/ija-care.v9i1.660.

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Palmoplantar Psoriasis is a chronic variant of Psoriasis that affect the skin of palms and soles, partially or completely with redness, dryness and thickness along with deep painful cracks leading to impairment in daily activities. The present case, 26-year-old male patient came with complaints of hyper pigmented dry scaly lesions with cracks on both palms and soles associated with itching, pain, mild erythema and pustulosis for the last one month. This was a diagnosed case of Palmoplantar Psoriasis having chronicity of 7-8 years on modern medicines with recurrent exacerbations. The features w
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5

H, Chaitra, C. M. Sreekrishnan, Asha K V, Gururaj Anil Bhat, and Poornima B. "ASSOCIATION OF DOOSHIVISHA IN KITIBHA KUSHTA (LICHEN PLANUS): A PREVALENCE STUDY." International Journal of Research in Ayurveda & Pharmacy 7, no. 4 (2016): 68–71. http://dx.doi.org/10.7897/2277-4343.074136.

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6

Chiniwar, Anuja S., and Shraddha Madar. "AYURVEDIC MANAGEMENT OF MOOKHADOOSHIKA (ACNE VULGARIS) W.R.T DOOSHIVISHA – A CASE REPORT." International Ayurvedic Medical Journal 12, no. 11 (2024): 2082–87. https://doi.org/10.46607/iamj2412112024.

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“Acne is not physically debilitating; it’s more so emotionally debilitating” Acne vulgaris is a chronic condition affecting more than 85% of adolescents and two-thirds of adults aged 18 years and older. It is a chronic inflam-matory disease of pilosebaceous units, characterised by seborrhea, open and closed comedones, papules, pus-tules, and, in more severe cases, nodules, pseudocysts and scarring. Acne is associated with more significant psychological burdens. In Ayurveda, acne symptoms resemble Mookhadooshika, mentioned under Kshudra ro-ga. Vitiation of Kapha Dosha, Vata Dosha and Rakta Dhat
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7

Shinde, PriyaPopatrao, and V. P. Joglekar. "EFFICACY STUDY OF PANCHARISHTA CHURNA IN DOOSHIVISHA WITH REFERENCE TO CONTACT DERMATITIS." International Journal of Research -GRANTHAALAYAH 5, no. 10 (2017): 290–306. http://dx.doi.org/10.29121/granthaalayah.v5.i10.2017.2305.

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The amazing journey of Ayurveda from its divine origin to the present day has left us wondering about enormous potential this science possesses. Its successful existence since time immemorial itself proves its scientific approach attributed to its unique principles that have remained unchanged till date. The Ayurveda is categorized into eight divisions, which collectively called Ashtang Ayurveda. Agadtantra is one among those branches.
 This dissertation is an attempt to study the efficacy of “Pancharishtachurna” in Dooshivish with special reference to contact dermatitis. The main purpose
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8

Dr., Priya Popatrao Shinde, and Dr.V.P.Joglekar Prof. "EFFICACY STUDY OF PANCHARISHTA CHURNA IN DOOSHIVISHA WITH REFERENCE TO CONTACT DERMATITIS." International Journal of Research - Granthaalayah 5, no. 10 (2017): 290–306. https://doi.org/10.5281/zenodo.1043387.

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The amazing journey of Ayurveda from its divine origin to the present day has left us wondering about enormous potential this science possesses. Its successful existence since time immemorial itself proves its scientific approach attributed to its unique principles that have remained unchanged till date. The Ayurveda is categorized into eight divisions, which collectively called Ashtang Ayurveda. Agadtantra is one among those branches. This dissertation is an attempt to study the efficacy of “Pancharishta churna” in Dooshivish with special reference to contact dermatitis. The main purpose of t
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9

Gopendra, Chandra Kamal *1, Kumar S. Bharati 2. Ashwini, and H. Gururaj 3. Chaitra. "DERMATOLOGICAL MANIFESTATIONS DUE TO TOXINS WITH SPECIAL REFERENCE TO VISHA." International Journal of Research - Granthaalayah 6, no. 4 (2018): 61–71. https://doi.org/10.5281/zenodo.1241457.

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Background: Ayurveda treatises are collection of vast knowledge regarding medical and environmental aspects. It has a separate branch called Agada Tantra which deals with the toxicological aspects. We aim to evaluate this knowledge regarding dermatological manifestation due to Visha (toxins) vis-à-vis contemporary knowledge. Method: The references available regarding the different types of poison and their dermatolgical manifestations in classical text were studied and compared with the available information in the contemporary medical literatures. Results: The term Visha and its types
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10

Kamal, Gopendra Chandra, Ashwini Kumar S. Bharati, and Chaitra H. Gururaj. "DERMATOLOGICAL MANIFESTATIONS DUE TO TOXINS WITH SPECIAL REFERENCE TO VISHA." International Journal of Research -GRANTHAALAYAH 6, no. 4 (2018): 61–71. http://dx.doi.org/10.29121/granthaalayah.v6.i4.2018.1476.

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Background: Ayurveda treatises are collection of vast knowledge regarding medical and environmental aspects. It has a separate branch called Agada Tantra which deals with the toxicological aspects. We aim to evaluate this knowledge regarding dermatological manifestation due to Visha (toxins) vis-à-vis contemporary knowledge.
 Method: The references available regarding the different types of poison and their dermatolgical manifestations in classical text were studied and compared with the available information in the contemporary medical literatures.
 Results: The term Visha and its t
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11

Sundaramourthy, Divyashri, S. K. Venkateshperumal, Balram Mishra, and Mohamed Muzzammel. "Cancer through the ayurvedic lens: An agadatantra path to healing." Ayush Journal of Integrative Oncology 1, no. 3 & 4 (2024): 40–45. https://doi.org/10.4103/ajio.ajio_12_24.

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Cancer is a complicated illness, and its therapies, such as chemotherapy and radiotherapy, frequently lead to harmful side effects. Ayurveda perceives cancer through concepts such as Viruddhahara and Visha, offering a framework to evaluate disease development and inform treatment by restoring balance in Doshas (biological energies) and revitalizing Dhatus (tissues). Aacharya’s age-old idea of Visha describes the phases of illness, highlighting the role of Doshic imbalances and diminished Dhatus in cancer development. Vishachikitsa (study of ayurvedic management of poison), part of Ayurveda, ex
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12

Shinde, Vitthal, and Nilima Wadnerwar. "Comparative evaluation of efficacy of Pippalyadi Agada as an adjuvant drug vs. standard drug therapy in the management of acute food poisoning: A Study Protocol." F1000Research 13 (April 23, 2024): 361. http://dx.doi.org/10.12688/f1000research.141879.1.

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Antimicrobial resistance, a pressing challenge in modern medicine, arises from excessive antibiotic use in veterinary and human care. Underreporting and complex links between food contamination and illnesses have led to underestimating foodborne disease impacts. The World Bank’s 2019 analysis projected $15B annual treatment costs and $95.2B productivity loss in low- to middle-income countries due to foodborne diseases. “Agada” refers to symptom-relieving medications, like “Vishaghnakalpa.” Pippalyadi Agada, from Vishaghana plants, treats “Dooshivisha Chikitsa,” e.g., Kitibha, rashes, shwas. It
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13

Hukkeri, Shilpa, and Mahesh P. Savalagimath. "Dooshivishari Agada: A Herbo-Mineral compound and its Standardization." Indian Journal of Ancient Medicine and Yoga 8, no. 1 (2015): 25–30. http://dx.doi.org/10.21088/ijamy.0974.6986.8115.3.

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14

Chalakh, Sonali, Minakshi Urkude, and Anita Wanjari. "Physicochemical and Phytochemicals investigation of Dooshivishari Agada by HPLC." International Journal of Ayurvedic Medicine 13, no. 4 (2023): 1013–16. http://dx.doi.org/10.47552/ijam.v13i4.3080.

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Background: Dooshivishari Agad (DA) is an herbal formulation that has been documented in Indian Traditional Medicine as a remedy for latent poisoning. Objective: this research was conducted to study Physicochemical parameter & Phytochemical analysis of DA by HPLC. Methods: It includes authentication of raw drugs and preparation of DA. Physicochemical parameter was tested by Loss on drying ,Acid insoluble Ash, Water soluble ash, Total ash value, Water & Alcohol soluble Extractive Value. HPLC was used for phytochemical screening. Observation: In analytical study obtained values are Loss
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15

Rani, Jyoti, and MaheshP Savalagimath. "Effect of Dooshivishari Agada over MSG-induced reproductive toxicity w.s.r. ovary and follicle count." AYU (An international quarterly journal of research in Ayurveda) 38, no. 1 (2017): 88. http://dx.doi.org/10.4103/ayu.ayu_166_17.

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16

Patil, Santosh F., Vishalaxi V. Shahapurkar, and Pukar Khanal. "Effect of an Ayurveda antidote Dooshivishari Agada in carboplatin induced myelosuppression in Male Wistar rats." Journal of Ayurveda and Integrative Medicine 13, no. 3 (2022): 100599. http://dx.doi.org/10.1016/j.jaim.2022.100599.

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17

Sajwan, Reena, Ramesh Chandra Tiwari, Manisha Dikshit, Ved Bhushan Sharma, and Bhawana Mittal. "A MANAGEMENT OF SHWITRA BY AYURVEDIC MEDICINES – A CASE STUDY." International Ayurvedic Medical Journal 11, no. 7 (2023): 1743–49. http://dx.doi.org/10.46607/iamj4511072023.

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Skin disorders are common manifestation in present era and Shwitra being one of them, affects not only the quality of life but also the psychological state of mind, social wellbeing and economic growth of a person. This disease has become a major social embarrassment and economic burden for the patient. Thus, the following article discusses the method of treatment of the disease using Ayurvedic treatment methods including Shaman Aushadhi (Kushtahar yog, Kandughana churna and Dooshivishari gulika etc). Based on the signs and symptoms observed in the patient, a treatment protocol was advised. It
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18

Deepa P, Nataraj H R, Anushree C G, and Akshatha K Shirwar. "A Critical Review on Dooshivishari Agada: A Herbo Mineral Formulation." International Journal of Ayurveda and Pharma Research, November 13, 2022, 70–77. http://dx.doi.org/10.47070/ijapr.v10i10.2576.

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Dooshivisha (cumulative toxicity) is a type of Kritrima visha (artificial poison). It is a transformed state of other types of poison if not eliminated, get collected in small doses leads to this type of poisoning. It is a unique concept of Ayurveda and is the cause of the majority of the health issues in the present era. Acharyas have said different treatment principles for the management of Dooshivisha (cumulative toxicity). Dooshivishari agada is the formulation of choice for its treatment, which is a herbo-mineral formulation comprised of twelve ingredients that are taken in equal amounts
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19

Kulkarni, Dr Neha. "CONCEPTUAL STUDY OF “DOOSHIVISHA” WITH SPECIAL REFERENCE TO BRUHATRAYEE." World Journal of Pharmaceutical Research, October 1, 2017, 1641–47. http://dx.doi.org/10.20959/wjpr201710-9515.

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20

Aswathi G, Manju S R, and Shiji R S. "Effect of Arka Taila and Patoladi Gana Kashaya in Dooshivishajanya Vicharchika." International Journal of Ayurveda and Pharma Research, June 5, 2022, 28–36. http://dx.doi.org/10.47070/ijapr.v10i5.2377.

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Toxicology, is a slow acting less potent poison, which does not kill the person immediately, but gets manifested in the form of many diseases. Skin diseases (Kustha) are one among the main symptoms of Dooshivisha. Vicharchika, is one among Kshudra kustha, which is highly prevalent, common and distressing condition. Recurrence and chronicity are the main threat faced by patients suffering from Vicharchika. Most of the features of Vicharchika show similarity with symptoms of the disease entity, eczema of modern dermatology. In India, the point prevalence of dermatological cases are 9.25%, and th
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21

Patil, Dr Pradeep, Patil K. S., Hande Sudarshan, Pawar Vinay, Mujumdar Amit, and Mhatre Ashish. "Conceptual study of Dooshivisha (Cumulative toxicity) w.r.t. Ancient classics and Modern science." Journal of Ayurveda and Integrated Medical Sciences (JAIMS) 1, no. 3 (2016). http://dx.doi.org/10.21760/jaims.v1i3.4431.

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Ayurveda describes the vast turnover of beauty aid products. More and more new synthetic substances are introduced every day. Many of these are not adequately tested for safety, in particular for routes other than oral or parenteral. Increased incidence of skin conditions like eczema and contact dermatitis after using newer cosmetics suggest that this may be due to local toxic effects or toxic effects manifested on this phenomenon as Dooshivisha. They are relevant to the current way of life considering the prevalence of pollution, occupational hazards and extent of exposure to toxins in food a
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Mukhedkar, Ankita Sunil, and Dipti Ajay Chavan. "Ayurveda Descriptions of Garavisha, Dooshivisha and Viruddhahara their Pathological Manifestations and Management." Himalayan Journal of Health Sciences, March 15, 2023, 10–13. http://dx.doi.org/10.22270/hjhs.v8i1.164.

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Visha is considered something that causes harm to all human being, the invasion of Visha in human body leads pathological manifestation. The Visha also becomes causes of death in some conditions if not treated properly. Ayurveda described various concept related to the Visha including Dushi visha, Gara visha and Viruddhahara. Dushi visha represents damaged and spoiled poison. The term Dushi itself means attenuated and denatured. These poison (Dushi visha) acts as latent toxin or exhibited cumulative toxicity inside the body. Similarly use of powder of insects can act as Gara Visha, the hazardo
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23

Suryakant, Kakde Suvarna, Patil Smita, Rajkumar Gupta, and Kakde Pravin Suryakant. "Safety and Efficacy of Charakokta Raktapachak Yoga in Patients of Urticaria (Kotha) Caused Due to Dooshivisha – A Randomized Controlled Trial." International Journal of Life Science and Pharma Research, March 1, 2024. http://dx.doi.org/10.22376/ijlpr.2024.14.2.p1-p15.

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This controlled clinical study aimed to assess the safety and efficacy of Charkokta Raktapachak Yoga in treating DooshivishajanyaKotha (urticaria), a condition known for its challenging recurrence. Two groups, each comprising 30 patients, were formed: a standard groupreceiving Tab. Cetrizine 10mg OD, and an experimental group receiving Tab. Raktapchak Yoga 500mg/day in two divided doses for 42 days.Follow-ups occurred every 7 days. The study evaluated manifestations such as raised edematous swelling (kotha), itching (kandu), burningsensation (daha), and pricking sensation (toda). Objective par
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Arya G. Surendran, Pravith N.K, and Sreekutty R.S. "Strachan-Scott Syndrome: Ayurvedic Perspective." International Journal of Ayurveda and Pharma Research, March 5, 2024, 117–21. http://dx.doi.org/10.47070/ijapr.v12i2.3138.

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Strachan Scott Syndrome also known as Tropical Ataxic Polyneuropathy (TAN) is a rare neurological disorder characterized by the lesions involving skin and mucous membrane, optic neuropathy and peripheral neuropathy, likely to be caused due to chronic cyanide intoxication following dependency to single plant component, cassava. It is considered as a disease of poor tropical populations but lacks a clear statistics on how many people are affected worldwide, but in affected population prevalence have been noted in more than a quarter. A very little is known about its incidence in India. The clini
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25

Avinash A and Seemaja G. "Ayurvedic Management of Herpes Zoster." International Journal of Ayurveda and Pharma Research, April 10, 2025, 72–76. https://doi.org/10.47070/ijapr.v13i3.3606.

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Herpes zoster, commonly known as shingles, is a viral disease caused by the reactivation of the varicella zoster virus. In India, from January 2015 to May 2021, there were 1,269 chickenpox outbreaks, resulting in 27,257 cases. Diagnosis of herpes zoster is based on severe pain, unilateral distribution, and the presence of grouped vesicles on erythematous, edematous skin, which rapidly evolve into pustules and then crust. Complications such as postherpetic neuralgia (10.2-54.7%) and secondary bacterial infections (3.5-21.0%), pose significant challenges in treatment. Contemporary medicine appro
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A, Vinay, S. B. Saswihalli, Sachidanand D. Vangapati, Shreekant Patil, and P. B. Apraj. "A Comparative Clinical Study Of Efficacy Of Swethakaraviradi TailaAnd Karanja Beeja TailaAlong With Dooshivishari AgadaIn The Management Of Psoriasis." International Research Journal of Ayurveda & Yoga 04, no. 06 (2021). http://dx.doi.org/10.47223/irjay.2021.4601.

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