Academic literature on the topic 'Dorsal-ventral patterning; Chick'

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Journal articles on the topic "Dorsal-ventral patterning; Chick"

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Altabef, M., J. D. Clarke, and C. Tickle. "Dorso-ventral ectodermal compartments and origin of apical ectodermal ridge in developing chick limb." Development 124, no. 22 (1997): 4547–56. http://dx.doi.org/10.1242/dev.124.22.4547.

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We wish to understand how limbs are positioned with respect to the dorso-ventral axis of the body in vertebrate embryos, and how different regions of limb bud ectoderm, i.e. dorsal ectoderm, apical ridge and ventral ectoderm, originate. Signals from dorsal and ventral ectoderm control dorso-ventral patterning while the apical ectodermal ridge (AER) controls bud outgrowth and patterning along the proximo-distal axis. We show, using cell-fate tracers, the existence of two distinct ectodermal compartments, dorsal versus ventral, in both presumptive limb and flank of early chick embryos. This orga
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Logan, C., A. Hornbruch, I. Campbell, and A. Lumsden. "The role of Engrailed in establishing the dorsoventral axis of the chick limb." Development 124, no. 12 (1997): 2317–24. http://dx.doi.org/10.1242/dev.124.12.2317.

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Expression and mutation analyses in mice suggest that the homeobox-containing gene Engrailed (En) plays a role in dorsoventral patterning of the limb. During the initial stages of limb bud outgrowth, En-1 mRNA and protein are uniformly distributed throughout the ventral limb bud ectoderm. Limbs of En-1(−/−) mice display a double dorsal phenotype suggesting that normal expression of En-1 in the ventral ectoderm is required to establish and/or maintain ventral limb characteristics. Loss of En-1 function also results in ventral expansion of the apical ectodermal ridge (AER), suggesting that En-1
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Cygan, J. A., R. L. Johnson, and A. P. McMahon. "Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants." Development 124, no. 24 (1997): 5021–32. http://dx.doi.org/10.1242/dev.124.24.5021.

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Classical embryological experiments have demonstrated that dorsal-ventral patterning of the vertebrate limb is dependent upon ectodermal signals. One such factor is Wnt-7a, a member of the Wnt family of secreted proteins, which is expressed in the dorsal ectoderm. Loss of Wnt-7a results in the appearance of ventral characteristics in the dorsal half of the distal limb. Conversely, En-1, a homeodomain transcription factor, is expressed exclusively in the ventral ectoderm, where it represses Wnt-7a. En-1 mutants have dorsal characteristics in the ventral half of the distal limb. Experiments in t
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Prin, Fabrice, Cairine Logan, Deana D'Souza, Monica Ensini, and Danielle Dhouailly. "Dorsal versus ventral scales and the dorsoventral patterning of chick foot epidermis." Developmental Dynamics 229, no. 3 (2004): 564–78. http://dx.doi.org/10.1002/dvdy.20007.

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Araujo, M., M. E. Piedra, M. T. Herrera, M. A. Ros, and M. A. Nieto. "The expression and regulation of chick EphA7 suggests roles in limb patterning and innervation." Development 125, no. 21 (1998): 4195–204. http://dx.doi.org/10.1242/dev.125.21.4195.

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Eph receptors and their ligands, the ephrins, have been implicated in early patterning and axon guidance in vertebrate embryos. Members of these families play pivotal roles in the formation of topographic maps in the central nervous system, the formation of brain commissures, and in the guidance of neural crest cells and motor axons through the anterior half of the somites. Here, we report a highly dynamic expression pattern of the chick EphA7 gene in the developing limb. Expression is detected in discrete domains of the dorsal mesenchyme from 3 days of incubation. The expressing cells are adj
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Charlebois, T. S., J. J. Henry, and R. M. Grainger. "Differential cytokeratin gene expression reveals early dorsal-ventral regionalization in chick mesoderm." Development 110, no. 2 (1990): 417–25. http://dx.doi.org/10.1242/dev.110.2.417.

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The induction and spatial patterning of early mesoderm are known to be critical events in the establishment of the vertebrate body plan. However, it has been difficult to define precisely the steps by which mesoderm is initially subdivided into functionally discrete regions. Here we present evidence for a sharply defined distinction between presumptive dorsal and presumptive ventral regions in early chick mesoderm. Northern blot and in situ hybridization analyses reveal that transcripts corresponding to CKse1, a cytokeratin gene expressed during early development, are present at high levels in
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Pizette, Sandrine, Cory Abate-Shen, and Lee Niswander. "BMP controls proximodistal outgrowth, via induction of the apical ectodermal ridge, and dorsoventral patterning in the vertebrate limb." Development 128, no. 22 (2001): 4463–74. http://dx.doi.org/10.1242/dev.128.22.4463.

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Dorsoventral (DV) patterning of the vertebrate limb requires the function of the transcription factor Engrailed 1 (EN1) in the ventral ectoderm. EN1 restricts, to the dorsal half of the limb, the expression of the two genes known to specify dorsal pattern. Limb growth along the proximodistal (PD) axis is controlled by the apical ectodermal ridge (AER), a specialized epithelium that forms at the distal junction between dorsal and ventral ectoderm. Using retroviral-mediated misexpression of the bone morphogenetic protein (BMP) antagonist Noggin or an activated form of the BMP receptor in the chi
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Pera, E. M., and M. Kessel. "Patterning of the chick forebrain anlage by the prechordal plate." Development 124, no. 20 (1997): 4153–62. http://dx.doi.org/10.1242/dev.124.20.4153.

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We analysed the role of the prechordal plate in forebrain development of chick embryos in vivo. After transplantation to uncommitted ectoderm a prechordal plate induces an ectopic, dorsoventrally patterned, forebrain-like vesicle. Grafting laterally under the anterior neural plate causes ventralization of the lateral side of the forebrain, as indicated by a second expression domain of the homeobox gene NKX2.1. Such a lateral ventralization cannot be induced by the secreted factor Sonic Hedgehog alone, as this is only able to distort the ventral forebrain medially. Removal of the prechordal pla
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Nowicki, J. L., and A. C. Burke. "Hox genes and morphological identity: axial versus lateral patterning in the vertebrate mesoderm." Development 127, no. 19 (2000): 4265–75. http://dx.doi.org/10.1242/dev.127.19.4265.

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The successful organization of the vertebrate body requires that local information in the embryo be translated into a functional, global pattern. Somite cells form the bulk of the musculoskeletal system. Heterotopic transplants of segmental plate along the axis from quail to chick were performed to test the correlation between autonomous morphological patterning and Hox gene expression in somite subpopulations. The data presented strengthen the correlation of Hox gene expression with axial specification and focus on the significance of Hox genes in specific derivatives of the somites. We have
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Arkell, R., and R. S. Beddington. "BMP-7 influences pattern and growth of the developing hindbrain of mouse embryos." Development 124, no. 1 (1997): 1–12. http://dx.doi.org/10.1242/dev.124.1.1.

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The expression pattern of bone morphogenetic protein-7 (BMP-7) in the hindbrain region of the headfold and early somite stage developing mouse embryo suggests a role for BMP-7 in the patterning of this part of the cranial CNS. In chick embryos it is thought that BMP-7 is one of the secreted molecules which mediates the dorsalizing influence of surface ectoderm on the neural tube, and mouse surface ectoderm has been shown to have a similar dorsalizing effect. While we confirm that BMP-7 is expressed in the surface ectoderm of mouse embryos at the appropriate time to dorsalize the neural tube, w
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Dissertations / Theses on the topic "Dorsal-ventral patterning; Chick"

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Buxton, Paul Graeme. "Embryonic roles for the slug regulatory gene in hindbrain regulation and limb patterning." Thesis, University College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266133.

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