Dissertations / Theses: 'Dosvit'

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Martínek, Michal. "Osvětlovací technika moderních vozidel a měření dohlednosti na dosvit hlavních světlometů." Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2011. http://www.nusl.cz/ntk/nusl-232559.

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This magister’s thesis is about modern lighting of vehicles, the visual range and afterglow in poor visibility. The first part of the thesis provides a detailed analysis of the current situation and problems, including a comprehensive description of the sources of light radiation, lamps, structures, and describe the systems used in modern lighting technology of vehicles. In the second part of the thesis there are the scientific methods to determine the issue of visual range and afterglow of the headlights. The second part is about the application of acquired techniques to detect an afterglow and the visual range of vehicles with modern headlights with a light source with xenon lamp, compared with a vehicle with a halogen lamp and a vehicle with an older halogen headlight.

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Suchomel, Filip. "Porovnání světelných parametrů různých světelných zdrojů předních světlometů vozidel." Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2019. http://www.nusl.cz/ntk/nusl-402104.

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This thesis is focused on comparison of parameters of light sources (halogen, xenon, LED) installed in Skoda Octavia 3rd generation. The opening part solves analysis of the current state of lighting technology and its impact on traffic safety. The next part is focused on general parameters of light, construction of light sources, optical systems and adaptation of the human eye to various light conditions, especially contrast. The practical part is focused on comparing the contrast values of individual light sources in relation to the dark and lightly dressed pedestrian in the area without artificial lighting.

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Balharová, Gabriela. "Možnosti osvětlení vozidel pro zvýšení bezpečnosti silničního provozu." Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2012. http://www.nusl.cz/ntk/nusl-232650.

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This master’s thesis deals with the possibilities of illumination of motor vehicles. Thesis is divided into two sections, from which the first discusses precisely the possibilities of lighting of motor vehicles at the present time. What are the modern lighting techniques, that can be found on the market and what is their impact on safety enhancement in road traffic. Second section is about the practical measurement of low and high beam afterglow. This measurement is being compared between two types of headlamps, namely halogen headlights and xenon headlights. Part of the measurement is as well measurement of illumination intensity precisely for these headlights. The output of measurement is the creation of own illumination intensity diagrams and afterglow diagrams of particular headlights, in comparison to isolux diagrams provided by the headlights manufacturer. Consequently are solved the issues about utilization of the isolux diagrams in expert praxis.

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Maxera, Pavel. "Porovnání výsledků experimentálních měření dohlednosti s dostupným SW." Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2012. http://www.nusl.cz/ntk/nusl-232646.

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This master's thesis deals with the analysis of comparison the results of experimental measurements of visibility with the software Dohľadnosť 2.0. Based on the specifications obtained by measuring in the field evaluates, whether the results acquired from the software by simulating an identical situation are consistent and therefore applicable for an expertise activities in solving the analysis of road-traffic accident.

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Díaz, Herbas Ricardo Matías. "Desarrollo de una metodología para determinar uniformidad de dosis en aerosoles de dosis medida utilizando un dispositivo recolector de dosis." Tesis, Universidad de Chile, 2006. http://repositorio.uchile.cl/handle/2250/105502.

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Cámara, Rey Elena. "L’increment de la dosi gènica com a estratègia de millora de la producció de proteïnes recombinants al llevat Pichia pastoris: revertint les limitacions genètiques del sistema biològic." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/399833.

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La producció de proteïnes recombinants ha esdevingut la opció predilecta per la producció de productes biofarmacèutics i enzims industrials. Com a factories cel·lulars, els llevats presenten nombroses avantatges enfront d’altres microorganismes, com la seva capacitat per realitzar modificacions post-traduccionals a les proteïnes, l’ampli ventall d’eines genètiques i la facilitat per créixer a altes densitats, entre d’altres. En aquest context, la idoneïtat del llevat metilotròfic Pichia pastoris en la producció de proteïnes recombinants ha destacat per sobre del llevat clàssic Saccharomyces cerevisiae, presentant una rellevància creixent en la producció de productes comercials recombinants. Entre d’altres factors, la presència del promotor AOX1 (PAOX1), d’expressió elevada i fortament regulat pel metanol, ha contribuït a la popularitat d’aquest sistema d’expressió. Per tal de millorar la producció de proteïna recombinant, s’han provat diverses estratègies, sent l’increment de la dosi gènica una de les més populars. Tot i que es pot obtenir una millora de la productivitat heteròloga amb aquesta metodologia, elevades dosis gèniques normalment comporten una sobrecàrrega metabòlica que deriva en productivitats baixes. Durant el transcurs d’aquesta tesi, s’ha utilitzat la lipasa de Rhizopus oryzae (Rol) com a proteïna model, expressada sota el control de PAOX1. Primer, es va construir una col·lecció de soques de P. pastoris amb un nombre creixent de còpies de ROL, i es va descriure per primer cop l’ús de la ddPCR (de l’anglès Droplet Digital PCR) per la determinació acurada de la dosi gènica a P. pastoris, demostrant una precisió més elevada que amb l’ús de la qPCR (de l’anglès quantitative real-time PCR) convencional. Segon, es va realitzar un estudi transcriptòmic mitjançant microarrays d’un grup de soques multicòpia, per tal d’entendre millor l’impacte de la dosi gènica de ROL a les rutes metabòliques. Concretament, les dades van revelar una forta regulació negativa de les rutes relacionades amb el metanol (entre d’altres), en consonància amb les dades fisiològiques obtingudes, que mostraven que les taxes de consum de la font de carboni i el creixement cel·lular eren dependents del nombre de còpies. A partir d’aquestes observacions, es va modificar una soca amb 4 còpies de ROL per tal que expressés una variant desregulada del factor de transcripció Mxr1, principal regulador de la ruta del metanol. Les dades fisiològiques i els nivells transcripcionals dels principals gens implicats en el metabolisme del metanol van confirmar la millora en la producció de Rol i l’increment en l’expressió dels gens relacionats amb el metanol i ROL. Finalment, es va dur a terme un estudi comparatiu a nivell transcriptòmic de la resposta de P. pastoris a l’expressió de tres proteïnes recombinants diferents, per tal d’estudiar l’impacte de la complexitat proteica i l’ús de sistemes d’expressió constitutius o induïbles. En resum, el present estudi descriu per primera vegada una aproximació a nivell de sistema de l’impacte d’una dosi gènica creixent en el llevat P. pastoris, permetent així el disseny de noves estratègies d’enginyeria cel·lular per tal de generar soques més productores, mitjançant la biologia sintètica i l’enginyeria metabòlica.
Recombinant protein production is becoming the preferred option to synthesized biopharmaceutical and industrial enzymes. As a host system, yeast factories provide numerous advantages over other microorganisms, such as their capacity to perform post-translational protein modifications, the wide genetic available tools, and the facility to growth at high densities, among others. In this context, the suitability of methylotrophic yeast Pichia pastoris for recombinant protein production has stand out over the classical yeast Saccharomyces cerevisiae, presenting an increasing relevance for the production of commercial recombinant products. Among several factors, the presence of the strong and tightly regulated AOX1 promoter (PAOX1) has contributed to the popularity of this expression system. To further increase the recombinant protein production, several strategies have been attempted, being the increase of the heterologous gene dosage one of the most widely reported. Although a heterologous productivity improvement can be achieved with this methodology, high gene dosages normally entail a metabolic burden in the cell that results in lower productivities. In the course of this thesis, it has been used the lipase of Rhizopus oryzae (Rol) as a protein model expressed under the control of the PAOX1. Firstly, we constructed a series of P. pastoris strains harbouring an increase gene dosage of ROL, and we reported for the first time the use of Droplet Digital PCR (ddPCR) for an accurate copy number determination in P. pastoris, allowing a higher precision than using conventional quantitative real-time PCR (qPCR). Secondly, a transcriptomic study of a set of multicopy strains was carried out using microarrays, to better understand the impact of ROL gene dosage on the metabolic pathways. Concretely, transcriptomic data revealed a high downregulation of methanol-related pathways (among others), in agreement with the physiological data that had been showed that C-source uptake rate and growth yields were gene dosage dependents. Based on these observations, a strain carrying 4 copies of ROL was remodified to express a deregulated variant of the Mxr1 transcription factor, the main regulator of methanol metabolism. Physiological data and transcriptional levels of the main genes involved in methanol metabolism confirmed the improvement of Rol production and the increasing expression levels of methanol-related genes and ROL. Finally, it was performed a comparative transcriptomic analysis of the response of P. pastoris to the expression of three different recombinant proteins, to study the impact of protein complexity and the use of constitutive or inducible expression systems. Overall, in the present study we describe the first systems-level approach to determine the impact of increasing gene dosage in the yeast P. pastoris, hence allowing the design of novel cell engineering strategies to generate high-producing strains by means of the synthetic biology and metabolic engineering.

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Tiedge, Oliver. "Kombinationswirkungen nicht linearer Dosis-Wirkungsbeziehungen." Doctoral thesis, kostenfrei, 2008. http://nbn-resolving.de/urn/resolver.pl?urn=nbn:de:bvb:20-opus-28522.

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Nascimento, Danilo de Oliveira 1974. "Dossie Sergio : o ateneu como romance de formação." [s.n.], 2000. http://repositorio.unicamp.br/jspui/handle/REPOSIP/269511.

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Orientador: Maria Eugenia Boaventura
Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Estudos da Linguagem
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Resumo: O trabalho analisa O Ateneu baseado na acepção tradicional do Bildungsroman ( romance de formação), cujo paradigma é Os anos de aprendizado de WilhelmMeister (Goethe). Este tipo de romance ressalta o aperfeiçoamento humano e tem sido considerado como gênero literário. O termo Bildungsroman foi incorporado ao léxico brasileiro por Massaud Moisés no Dicionário de Termos Literários, que o define como uma narrativa que lida com a experiência dos personagens vivida durante a educação ou os anos de formação. Fábio Lucas reconhece O Ateneu como um romance de fonnação de grande expressão nacional.Como um programa narrativo, o Bildungsroman considera o desejo do herói pela fonnação, a substituição da casa paterna pelo universo formativo, o encontro com tutores, e a trajetória formativa do protagonista como uma maneira de entender e enfatizar sua fonnação e desenvolvimento. Assim este trabalho tem o objetivo de entender o caráter de Sérgio criança e, ao mesmo tempo o de Sérgio adulto. Nesta tentativa, também se enfatiza a idéia de O Ateneu incorporar intrinsecamente formação e deformação
Abstract: This work analyses o Ateneu based on the traditional aception of Bildungs roman (formation romance), whose paradigm is The Years of Apprenticeship of Wilhelm Meister (Goethe). This type of romance stands out the human improvement and has been considered as a titerary geme. The term Bildungsroman was incorporated into brazilian lexis by massaud Moisés in Dicionário de Termos Literários, which defines it as a narrative which deals with the characters experiences tived during the education or the formation yaers. Fábio Lucas recognizes O Ateneu as formation romance with a great national expression. As a narrativa program, the Bildungsroman considers the hero longing for teh formation, the substitution of partenal home into the formative universe, the meeting with tutors and the formative path of the protagonist as a way of understanding and emphasiging its formation and development. Thus, this work has the objective to understand the character of child Sérgio and, at the same lime, to ty to construct adult Sérgio character. In this attempt, it also emphasizes the idea of the Ateneu incorporates intrinsicallyformation and deformation
Mestrado
Teoria Literaria
Mestre em Letras

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Seidel, Dirk. "Trendtests für geordnete kategoriale Daten bei sehr kleinen Fallzahlen." [S.l. : s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=962076228.

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Marteleur, Jonatan, and Niklas Mannberg. "Vidareutveckling av doseringsmodul för Dosis®." Thesis, KTH, Hållbar produktionsutveckling (ML), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-254328.

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Dosis® är en digital doseringsask från Victrix AB som med hjälp av en inbyggd datorenhet kan ställas in för att påminna patienter om doseringstillfällen genom alarm, röstmeddelande och vibration. För att vidareanpassa Dosis® till patienter med kognitiva nedsättningar vill Victrix AB implementera en låsfunktion till doseringsfacken. Facken skall endast kunna öppnas under doseringstillfällen för att undvika felmedicinering. Detta arbete fokuserar på att skapa underlag för utvecklingen av denna låsfunktion till Dosis®. Genom att bryta ned låsets funktion i delfunktioner har koncept strategiskt kunnat utvecklas. Genom ett morfologiskt schema har utvalda konceptfragment från alla låsets delfunktioner slutligen kombinerats till sex potentiella lösningar.
Dosis® is a digital pill box from Victrix AB which has a built in computer unit that can be set to remind patients of when it’s time to take their medicine through alarm, voice messages and vibrations. To adapt Dosis® for patients with cognitive dysfunctions Victrix AB wants to implement an automated locking system. The locking system is supposed to prevent patients from opening pill compartments outside of the pre-set time for medication. By doing this Victrix AB hopes to decrease the risk of these patience overdosing. This work is focused on producing a basis from which an automated locking system could be designed. The function of the locking system was broken down into sub functions, making it possible to strategically develop new solutions. Through a morphological schedule chosen concept fragments where combined from all sub functions to finally produce six potential solutions.

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Lima, Marlise Borges de. "Dossiê Walter Freitas: comunicação, arte e cultura na Amazônia." Pontifícia Universidade Católica de São Paulo, 2013. https://tede2.pucsp.br/handle/handle/4577.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico
This thesis aims mainly to bring major contributions to the study of Brazilian and Amazon culture through the processes of creation and mediation of art and communication, which are in the cultural-artistic work of Walter Freitas, who is a writer, playwright, musician and composer of Pará. It seeks to understand the extent of his art: how much it can do to resonate amazonidade and the fundamental knowledge of this culture and also activate a certain collective memory, since the translation of the Amazon culture present in the artistic production of this author is full of facts that relate to a whole society. Freitas performs thus a work of art, culture and communication that reaches universal dimensions. In music, theater or literature, he builds and rebuilds poetics that fulfill their role as an alternative way. In the language of sound he creates a new musical aesthetic as inserts rhythms, irregular beats, complex harmonic and melodic structures and masterfully vocalizes the indigenous and African subdialects. In scenic language he writes in verse and always tries to work the issue of theater from an experimental perspective. He approaches social, political and cultural themes (in poetic form), showing always a very rich reflection material about the traditions in the Amazon. The themes of migration of riparian peoples, forest preservation and other references that bring up issues related to the universal human condition, even from elements of this private culture are also present. In literature, Freitas appropriates 'physically' and enhances the popular language. He brings back expressions into disuse, adds new terms to the Indian and African dialects (existing) and reaches the refinement of inaugurating a new language when creating graphic signs (inverted accents, apostrophes at the beginning, middle and end of words) to mean peculiarities of pronunciations, sonorities, suppression of letters and phonemes. Thus, his verb-visual-sound artworks from the first to the last syllable, note and to scene constitute sequences split into kaleidoscope, which through the tiles finally materialize the structure of a unit . To approach the concepts of cultural translation and mediation in art/communication this thesis is based on the Semiotics of Culture, through the semioticists Yuri Lotman, Mikhail Bakhtin, and Paul Zumthor among others. In the territories of communication and culture it is based on the theories of Jesus Martin Barbero, Serge Gruzinski, Boaventura de Souza Santos and other authors who think of Brazil and Latin America as places of diverse elements multi-junctures and concerning about notions of racial mixing, popular culture, orality and memory on the studies of Amalio Pinheiro and Jerusa Pires Ferreira
Esta tese tem como objetivo principal trazer contribuições aos estudos de cultura brasileira e amazônica, através dos processos de criação e mediação em arte e comunicação, que estão no trabalho artístico-cultural de Walter Freitas, escritor, dramaturgo, músico e compositor paraense. Procura-se compreender a dimensão de sua arte: o quanto ela pode fazer ressoar a amazonidade e o conhecimento fundamental desta cultura e ainda ativar uma certa memória coletiva, uma vez que a tradução da cultura amazônica presente na produção artística deste autor é repleta de fatos que dizem respeito a todo um conjunto social. Freitas realiza, portanto, um trabalho de arte, cultura e comunicação, que ganha dimensões universais. Na música, no teatro ou na literatura, constrói e reconstrói poéticas que cumprem o seu papel de forma alternativa. Na linguagem sonora cria uma nova estética musical, quando insere ritmos, compassos irregulares, estruturas harmônicas e melódicas complexas e sonoriza, com maestria, os subdialetos indígenas e africanos. Na linguagem cênica escreve em versos e procura sempre trabalhar a questão do teatro a partir de uma perspectiva experimental. Aborda temas sociais, políticos e culturais (de forma poética), apresentando sempre um material muito rico de reflexão a respeito das tradições na Amazônia. Comparecem os temas da migração dos povos ribeirinhos, da preservação da floresta e outras referências, que trazem à tona questões universais inerentes à condição humana, mesmo partindo de elementos desta cultura, em particular. Na literatura, Freitas apropria-se 'fisicamente' da linguagem popular e a potencializa. Traz de volta expressões em desuso, acrescenta novos termos aos dialetos indígenas e africanos (já existentes) e chega ao requinte de inaugurar uma linguagem nova, ao criar sinais gráficos (acentos invertidos, apóstrofes no início, meio e final das palavras) para significar peculiaridades de pronúncias, sonoridades, supressão de letras e fonemas. Deste modo, suas obras de arte verbo-visual-sonoras, da primeira à última sílaba, da primeira à ultima nota e à ultima cena, se constituem em sequências desdobradas em caleidoscópio, que, passando pelos mosaicos, finalmente concretizam a estrutura de uma unidade. Para abordar os conceitos de tradução cultural e mediação em arte/comunicação, a pesquisa fundamenta-se na Semiótica da Cultura, através dos semioticistas Iuri Lotman, Mikhail Bakhtin, Paul Zumthor, entre outros. Nos territórios da comunicação e da cultura, as teorias de Jesus Martin Barbero, Serge Gruzinski e Boaventura de Souza Santos e outros autores, que pensam o Brasil e a América Latina como lugares de 'multiconfluências' de elementos diversos. E sobre noções de mestiçagem, cultura popular, oralidade e memória, foram utilizados os estudos de Amálio Pinheiro e Jerusa Pires Ferreira

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Vaz, Sofia Manuela Ribeiro. "Estágio na Direcção Geral de Arquivos: a concepção de uma exposição sobre a Guerra do Ultramar e a sua valorização num contexto educativo." Master's thesis, Faculdade de Ciências Sociais e Humanas, Universidade Nova de Lisboa, 2012. http://hdl.handle.net/10362/9057.

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Relatório de Estágio apresentado para cumprimento dos requisitos necessários à obtenção do grau de Mestre em Ciências da Informação e Documentação
Os arquivos não são apenas espaços onde os documentos estão conservados e guardados. A sua dimensão social e cultural faz com que o seu principal objectivo seja a difusão da informação que está à sua guarda. De entre as várias formas de difusão o presente texto, no âmbito do estágio do Mestrado em Ciências da Informação e Documentação no ramo dos Arquivos, aborda a das exposições e a dos serviços educativos. As exposições são uma forma de difusão mais tradicional, aquela que as instituições de arquivo utilizam para dar a conhecer os documentos que se encontram à sua guarda, para comunicar com a sociedade em que está inserido. Quanto aos serviços educativos, estes são de facto uma das formas de difusão que lentamente tem marcado presença nos arquivos portugueses. Com este trabalho tentamos demonstrar que este serviço tem grandes potencialidades na formação do cidadão através da aproximação com o sistema educativo nacional, e no estreitamento da relação entre os documentos e o mundo exterior ao contribuir para a criação de novas formas de contacto entre as duas partes. Numa sociedade cada vez mais exigente e onde a tecnologia tem um papel essencial, parece-nos primordial reflectir sobre formas de inovar e dinamizar um serviço com tantas potencialidades. Assim e constituindo o cerne de toda a problemática temos a questão: “Como podemos conceber uma exposição sobre a Guerra do Ultramar na DGARQ e valorizá-la num contexto educativo?” De forma a responder a esta questão procuraram-se alternativas para transformar uma simples exposição numa ferramenta didáctica e pedagógica através da utilização das novas tecnologias e da adaptação ao currículo nacional de ensino. Foi também criado um dossiê pedagógico cujo objectivo é fazer chegar os documentos de arquivo à sala de aula, e de tentar aproximar arquivos, arquivistas, professores e alunos.

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Schram, Laurence. "La caserne Dossin à Malines, 1942-1944: histoire d'un lieu." Doctoral thesis, Universite Libre de Bruxelles, 2015. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209094.

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Le 27 juillet 1942, la Sipo-SD de Bruxelles ouvre le camp de rassemblement pour Juifs, établi dans la caserne Dossin à Malines. La fonction de ce camp est génocidaire :elle consiste à rassembler en ce lieu les victimes des persécutions raciales en vue de leur « évacuation » à l’Est, c’est-à-dire leur déportation à Auschwitz-Birkenau.

Entre le 4 août 1942 et le 31 juillet 1944, 25.000 déportés juifs et 350 Tsiganes de Belgique et du nord de la France sont déportés à Auschwitz-Birkenau, qui est à la fois un centre de mise à mort et un complexe concentrationnaire. En 1945, seuls 1.252 de ces déportés raciaux ont survécu. Avec Drancy et Westerbork, la caserne Dossin constitue l’un des rouages essentiels de la mise en œuvre de la « Solution finale de la Question juive » (en Allemand, Endlösung der Judenfrage), le programme nazi d’élimination systématique et totale des Juifs d’Europe.

Bien que ce lieu ait été l’antichambre de la mort, son histoire est très mal connue. Pour la première fois, elle est étudiée dans sa globalité.

Après avoir donné un aperçu des persécutions raciales sous l’occupation allemande en Belgique et dans le nord de la France, l’auteur examine comment et dans quel contexte le camp de Malines est organisé par la Sipo-SD.

Le camp nécessite un personnel SS très restreint :une dizaine d’Allemands et quelque 80 auxiliaires flamands suffisent. Les rôles et les parcours individuels de plusieurs d’entre eux sont abordés plus en détail, afin d’en dégager des profils particuliers. Pour faire fonctionner le camp, les SS utilisent des travailleurs juifs détenus. Leurs tâches vont de l’entretien quotidien du camp à l’administration de la déportation, l’enregistrement sur les listes de transports et la spoliation. L’implication forcée des détenus dans la destruction de leur propre communauté est analysée. Le fonctionnement du SS-Sammellager est comparable à celui du système concentrationnaire. À la caserne Dossin, des détenus juifs endossent des fonctions privilégiées, similaires à celles des Kapos dans les camps de concentration, mais évidemment à des degrés de violence très éloignés.

Les SS, maîtres absolus, règnent par la terreur que les internés subissent dans tous les aspects de leurs conditions de détention :le règlement intérieur, les horaires, l’hygiène déplorable, la promiscuité dans les chambrées, l’insuffisance du ravitaillement, l’exploitation de leur travail.

L’arbitraire, renforcé par l’impunité dont jouissent les SS, débouche sur de nombreux mauvais traitements, exactions, et sévices. Certains épisodes, plus violents que d’autres, qui ont marqué l’histoire du camp, sont analysés en profondeur. Le nombre extrêmement restreint de décès survenus au camp doit cependant être souligné.

Devant tant de violences, confrontés à l’inacceptable, les internés adaptent leurs comportements aux circonstances, jouant sur un vaste registre allant de la collaboration avec leurs persécuteurs jusqu’à la résistance. Cette résistance, multiforme et diffuse, se développe à l’intérieur du camp, tout en n’aboutissant jamais à la mise sur pied d’un réseau organisé.

Mais au sein des détenus, une catégorie particulière n’aura jamais l’occasion de résister, pas plus que celle de se mêler aux internés juifs. Dès leur enfermement dans la caserne Dossin, les Tsiganes sont encore plus mal lotis que les Juifs. Leur sort, tout à fait exceptionnel et ne se confondant pas avec celui des Juifs, est présenté dans un chapitre qui leur est exclusivement consacré.

Dans la nuit du 3 au 4 septembre 1944, le SS-Sammellager est abandonné par les SS, en pleine débâcle. La plupart des Juifs qui s’y trouvent encore sont livrés à eux-mêmes. Leur « libération » ne suscite pas de grand intérêt. Pour leur part, la liesse s’éteint rapidement devant le constat de leur monde ravagé par la Shoah. Presque aucune famille n’est sortie indemne de ces deux années de déportation.

Vingt-sept transports juifs et un transport tsiganes ont été dirigés à Auschwitz-Birkenau. Trois convois exceptionnels partent aussi pour Buchenwald, Ravensbrück et Bergen-Belsen et deux petits groupes d’internés sont envoyés de Malines à Vittel.

L’histoire de chacun de ces transports permet de relater la façon dont leur effectif a été rassemblé, de suivre le sort des déportés, des évadés, des assassinés dès la descente du train, des forçats ainsi que des rares survivants.

Aussi l’auteur replace-t-il la caserne Dossin dans son contexte européen en mettant l’accent sur sa fonction génocidaire.

La mise en œuvre de la Shoah en Belgique, en France et aux Pays-Bas est présentée et une comparaison entre les camps de rassemblement de ces pays, Dossin, Drancy et Westerbork est réalisée.

Tout au long de son développement, cette thèse met l’accent sur la mission génocidaire du camp, maillon entre les SS l’Office central de Sécurité du Reich de Berlin et Auschwitz-Birkenau, le lieu de l’extermination des Juifs de l’Ouest. Le SS-Sammellager für Juden est replacé dans le contexte de la Shoah en Europe, en particulier à l’Ouest, dans le triangle formé par Westerbork, Drancy et Dossin.

Doctorat en Histoire, art et archéologie
info:eu-repo/semantics/nonPublished

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Moreira, Valeria de Moraes Vicente. "Sardade se escreve com r de Craudionor: dossie de um escolar." reponame:Repositório Institucional do FGV, 1987. http://hdl.handle.net/10438/8988.

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Before the need to define an awared known object to afford the accomplishment of the discourse, a thesis writer, from her very own trajectory while scholar, yields, from thereof, no longer a discourse pertaining to certain pedagogical procedures placed in discussion,but a fervent say for its unlikeness in relation to what makes up the discourse that is not aware of it as much as for its unawareness of the experience thus yielded.
Diante da necessidade de definir um objeto de conhecimento para viabilizar a consecução da dissertação, uma mestranda, recorrendo à sua própria trajetória enquanto aluna produz, desde este lugar, não mais um discurso sobre certos procedimentos pedagógicos colocados em questão, mas uma fala apaixonada por sua diferença em relação à que, constitui o discurso que nao a reconhece, tanto quanto nao reconhece o saber assim produzido.

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Caputo, Francesca. "Sintassi e dialogo nella narrativa di Carlo Dossi /." Firenze : Accademia della Crusca, 2000. http://catalogue.bnf.fr/ark:/12148/cb377577424.

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Tesi dott. ricerca--Scienze letterarie--Pavia--Università degli studi, Dipartimento di scienze della letteratura e dell'arte medievale e moderna.
Bibliogr. p. 211-228. Index. No de :"Studi di grammatica italiana", ISSN 0391-4151, 2000.

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Venkatachala, Jayanth. "Product development of Dosis locked daily pill box." Thesis, KTH, Skolan för industriell teknik och management (ITM), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-266944.

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Taking medication at the prescribed times is very important for people with mental issues like schizophrenia, dementia Alzheimer’s and depression. But their condition itself keeps them from doing so. They are either forgetful or choose not to take the pills intentionally. This could lead to missing dosage or overdosing both of which are dangerous to the person’s health. Hence a pill box that monitors the dosage and keeps them from being able to access the pills at undesired times is needed. The aim of the thesis is to design such a pill box for the company Victrix AB in Stockholm, Sweden, by expanding on their current pill box, Dosis. In the project, the locking mechanism to keep the lids closed was rigorously designed in phases after understanding the user conditions. The end result is a locked daily pill box that is ergonomic to use for people of all ages, mental and physical conditions. The product sets itself apart from its competitors by being compact, less medical looking and very easy to use.
Att ta mediciner vid föreskrivna tidpunkter är mycket viktigt för personer med psykiska problem som schizofreni, alzheimers, demens och depressioner. Dock kan deras tillstånd hindra dem från att göra det. De är antingen glömska eller så väljer de att inte ta medicinen avsiktligt. Sådant beteende kan leda till saknad dosering eller överdosering, vilka båda är farliga för personens hälsa. Därmed behövs en pillerask som övervakar doseringen och hindrar dem från att komma åt pillerna vid oönskade tidpunkter. Syftet med examensarbetet har varit att designa en sådan pillerask för företaget Victrix AB i Stockholm, Sverige, genom att utöka sin nuvarande ask, Dosis. I projektet designades låsmekanismen noggrant i faser, genom en ökad förståelse av användarförhållandena, för att hålla locken stängda,. Slutresultatet blev en låst daglig pillerask som är ergonomisk för personer i olika åldrar med mentala och fykiska problem. Produkten skiljer sig från dess konkurrenter genom att vara kompact, inte ha ett typiskt medicinskt utseende samt mycket enkel att använda.

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Ragnarsson, Anna-Lisa. "Hur apotekskunden delar sina tabletter och hur de förvaras." Thesis, Linnéuniversitetet, Institutionen för kemi och biomedicin (KOB), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-75441.

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Bakgrund: Läkemedelsordinationer som kräver delning av tabletter är vanligt och förekommer vid ca. 10 % av expedierade recept. Tabletter kan vara svåra att dela, ge smulor eller delas i olika stora delar vilket kan påverka patientens följsamhet till behandlingen och behandlingsresultat. Syftet med studien var att undersöka hur patienterna gör när den förskrivna tablettberedningen måste delas, samt hur kvarvarande delad tablett förvaras. Metod: Intervjustudie med apotekskunder som har ordination vilket kräver delning av tablettberedningar. Resultat: Av 7677 apotekskunder med recept, vid åtta apotek, hade 188 (2,4 %) dosering som krävde tablettdelning. 171 kunder deltog i intervjustudien angående upplevelser av tablettdelning. 66 % av deltagarna (113/171) var >65 år. 49 % (75/153) delade tabletten med fingrarna, 31 % (47/153) med kniv och 14 % (22/153) med tablettdelare. Sax, tång eller tänderna användes av 6 % (9/153). Fyra respondenter delade inte. Den kvarvarande tablettdelen förvarades i dosett av 50 % (69/139), 37 % (51/139) lade tillbaka tablettdelen i förpackningen, 8 % (11/139) använde en skål, fat eller ett glas. Slutsats: Hälften av respondenterna delade med verktyg, vilket tyder på att tabletterna var svåra att dela för hand. Andelen äldre och deras upplevelse av att tabletterna var små och svårhanterliga kan vara orsaken. Det övervägande användandet av dosett för förvaring av tabletthalvorna, kan bero på att fler läkemedel användes, vilket är vanligare vid högre ålder och förenklar läkemedelshanteringen.
Prescriptions that requires splitting tablets is common and occurs at 10 % of all prescriptions in Sweden. Causes why doctors prescribe dosages with split tablets could be the absence of appropriate strength when children and elderly people need lower dosages than those available on the market. Other reasons for splitting tablets can be problem with swallowing large tablets and economic considerations. Not all tablets are intended to be split and scored tablets do not always mean that the tablet can be split in two equal parts. Difficulties in splitting tablets, crumbling or different size of the tablet parts could affect the patient’s compliance and the outcome of the treatment. The aim of this study was to examine how the pharmacy customers do when the tablet must be split and how the remaining divided tablet is stored. Among 7677 customers with prescriptions, visiting eight pharmacies in Sweden, 188 (2,4%) were splitting tablets in half. Out of them 171 (2/3 women) accepted to participate in interviews to assess pros and cons in tablet splitting. 66% (113/171) of the respondents was at the age of 65 or older. 49% (75/153) split their tablets between the fingers, 31% (47/153) used a knife, 14% (22/153) used a tablet splitter. Scissor, pliers and teeth were used by 6% (9/153). Four respondents didn´t split their tablets. Medication for heart-/vessels and psychotropic drugs was used by 81% (139/171). The most commonly divided drug was Imovane® 7,5 mg (12%, 20/171), 50% (10/20) used a tool for splitting it, the rest used their fingers and many of them got different size of the parts. The split tablets were stored in a dosett for 50% (69/139) of the respondents, 37% (51/139) put it back in the packaging, 8% (11/139) laid it in a bowl, on a plate or in a glass. Half of respondents used a tool, which indicate for difficulties in splitting. The proportion of older people and experience of small and difficult broken tablets could be a reason. The major use of dosett for storage, may be due to the use of several drugs, which are more common in older ages and facilitates the drug treatment.

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Bini, Renan Paulo. "Primeira pessoa do plural em dossiê da revista Cult: traços de modalização." Universidade Estadual do Oeste do Paraná, 2018. http://tede.unioeste.br/handle/tede/4130.

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This research aims at investigating the use of the first person of plural in journalistic texts, so, it is taken into account the hypothesis that this subject of discourse can add epistemic modalization and different sense instances to the text, which are associated to ethos, pathos and logos categories of Rhetoric. Cutouts with occurrences on the first person of plural are analyzed in the text named as Feminist Conscience and Struggles: conquests and challenges in Brazil. This text shows the dossier Perceptions of Feminine and Feminist Actions, published in Cult/Edition Journal, 210/2016. The first query of this research is: could the first person of plural form delimit modifying effects in journalistic texts, as it happens in the cutouts selected for this analysis? Thus, in order to answer this demand, the overall goal of this research was verifying how the first person of plural works, as a modifying element and a rhetoric characteristic, in the text Conscience and feminist struggles: achievements and challenges in Brazil, concerning the Perceptions of Feminine and Feminist Actions dossier, in Cult Magazine. Thus, this study is explained by the state of art achievement has shown that there is little research on the PPP operation in journalistic texts and few researches that consider the PPP a rhetorical strategy. Regarding the use of this person's speech as a modalization strategy, no research was detected in the consulted academic databases. So, according to this subject, there is a perspective that discussion in journalistic texts is built up from the relationship among the text producer, textual subject-matter and the public-reader; and that the text producer handles with linguistic resources to act out on audience, in order to guide the meaning production when choosing content that will verbalize as well as how to do it, adhering to modalization. Thus, the theoretical basis of this research is constituted of research on Modalization and Rhetoric. Considering the evaluation of modification phenomena, there was some reflection on proposals such as those ones of Castilho and Castilho (1993), Campos (2001), Koch (2002), Miranda (2005) and Corbari (2013). Therefore, Mosca (2001), Aristotle (2017), Massmann (2017) and Perelman and Olbrechts-Tyteca (2017), among other researchers were studied to evaluate the rhetorical process. Sociolinguistic guidelines are also considered regarding the use of pronoun "we", as it can be observed in Lucchesi's proposal (2009), since it is a recurrent linguistic impress in corpus, considering engagement way of the text producer with the other persons of the discourse, although the author proposes categories when observing oral texts and this research aims at analyzing the written ones. The analyzes of the selected cutouts have shown that this person of discourse presents three dimensions of meaning in the text. It is highlighted that, although it concerns about a person of the discourse, the linguistic resource guides the senses in the text, if it is considered duly associated to the content of statements and image that is built of the text producer with the likely audience.
Investiga-se, por meio desta pesquisa, o uso da primeira pessoa do plural em texto jornalístico, considerando a hipótese de que essa pessoa do discurso pode agregar ao texto modalização epistêmica e diferentes instâncias de sentido vinculadas às categorias ethos, pathos e logos da Retórica. Tomam-se para análise recortes com ocorrências da primeira pessoa do plural no texto Consciência e lutas feministas: conquistas e desafios no Brasil, texto que apresenta o dossiê Percepções do Feminino e Ações Feministas, publicado na Revista Cult/Edição 210/2016. Parte-se da seguinte pergunta de pesquisa: A marca verbal de primeira pessoa do plural poderia demarcar efeitos modalizadores em textos jornalísticos, a exemplo do que ocorre nos recortes selecionados para esta análise? Para responder à problemática, tem-se o objetivo geral de verificar o funcionamento da primeira pessoa do plural, como elemento modalizador e como marca retórica, no texto Consciência e lutas feministas: conquistas e desafios no Brasil, do dossiê Percepções do Feminino e Ações Feministas, da Revista Cult. O estudo justifica-se considerando que a realização do estado da arte demonstrou que há poucas pesquisas sobre o funcionamento da PPP em textos jornalísticos e poucas pesquisas que consideram a PPP uma estratégia retórica. Já em relação à utilização desta pessoa do discurso como uma estratégia de modalização, não foram encontradas pesquisas nos bancos de dados acadêmicos consultados. Para esta proposição, parte-se da perspectiva de que a argumentação em textos jornalísticos se constrói a partir da relação entre o produtor do texto, a argumentação textual e o público-leitor; e de que o produtor do texto manipula recursos linguísticos para agirem sobre a plateia, orientando a produção de sentidos ao escolher o conteúdo que vai verbalizar e a forma de fazê-lo, imprimindo modalização. Assim, a base teórica desta pesquisa é composta, principalmente, por pesquisas sobre Modalização e Retórica. Considerando a avaliação dos fenômenos de Modalização, refletiu-se sobre propostas como as de Castilho e Castilho (1993), Campos (2001), Koch (2002), Miranda (2005) e Corbari (2013). Já para a avaliação da tessitura retórica, considerou-se Mosca (2001), Aristóteles (2017), Massmann (2017) e Perelman e Olbrechts-Tyteca (2017), entre outros pesquisadores. Também se consideram orientações da Sociolinguística relativas ao uso do pronome “nós”, como a proposta de Lucchesi (2009), visto que se trata de marca linguística recorrente no corpus, considerando a forma de engajamento do produtor do texto com as outras pessoas do discurso, embora o autor proponha categorias ao observar textos orais e nesta pesquisa objetiva-se analisar textos escritos. As análises dos recortes selecionados demonstram que esta pessoa do discurso apresenta, no texto, três dimensões de sentido. Nota-se que, apesar de se tratar de uma pessoa do discurso, o recurso linguístico orienta os sentidos no texto, se considerada devidamente atrelada ao conteúdo dos enunciados e à imagem que se constrói do produtor do texto com a provável plateia.

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Metten, Miriam. "Dosis-Wirkungs-Beziehung der Rücklagerung des Musculus obliquus inferior /." Freiburg i.Br, 2006. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000252818.

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Velásquez, Cabrera Carlos Eduardo. "Estimación de dosis absorbida en tomógrafos de poca vista." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2014. https://hdl.handle.net/20.500.12672/12044.

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Plantea tres objetivos en primer lugar es comprobar la viabilidad de uso de un tomógrafo de pocas vistas, para usos médicos e industriales, segundo es comprobar la eficiencia del algoritmo r-Art para la reconstrucción de imágenes en tomógrafos y por último es la estimación de dosis absorbida en dosis absorbida con datos obtenidos por el código Monte Carlo N-Particle 5. Se denominó un tomógrafo de pocas vistas al tomógrafo que irradia el objeto en estudio con pocos ángulos, lo que permite reducir el tiempo de exposición del objetivo a la radiación, por lo cual la cantidad de dosis también se reduce, causando menor daño a nivel celular. En este trabajo se presenta dos grupos de imágenes reconstruidas la primera con una pentium IV y el segundo grupo con un núcleo Core i5. Las imágenes del segundo grupo son superiores en calidad y resolución al del primer grupo, se espera que con una computadora portátil Core i7, las imágenes se comparen a la misma calidad de los de tomografía convencional. Llos ejemplos presentados se dan para aplicaciones en física médica y en forestal. Las dosis absorbidas son estimadas para tomógrafos de pocas vistas y es aproximadamente la décima parte de un tomógrafo convencional.
Tesis

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Silva, Wesley Pereira da. "Jogos digitais adaptados para estudantes com deficiência visual : estudo das habilidades cognitivas no dosvox." reponame:Repositório Institucional da UnB, 2017. http://repositorio.unb.br/handle/10482/23348.

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Dissertação (mestrado)—Universidade de Brasília, Faculdade de Educação, Programa de Pós-Graduação em Educação, 2017.
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A escola atual vive em uma perspectiva inclusiva, tendo que se adequar às necessidades de todos os alunos, sejam eles pessoas com deficiência ou não. As necessidades de cada um de nós vão além das necessidades básicas, precisamos também de diversão, lazer e uma oferta de ensino diferente da oferecida tradicionalmente. A pessoa com deficiência visual necessita de alternativas para o processo de ensino-aprendizagem e o jogo é uma excelente opção. Dentro da infinidade de tipos de jogos que encontramos, o jogo digital é o que mais ascendeu nos últimos anos, principalmente, entre os jovens. Hoje, vários jogos digitais foram adaptados e novos jogos digitais foram criados para que a pessoa com deficiência visual possa utilizar essa ferramenta lúdica. O jogo digital adaptado para a pessoa com deficiência visual pode proporcionar o aprimoramento de algumas habilidades individuais. Esta pesquisa consiste no estudo da interação entre o aluno e os jogos digitais adaptados presentes no sistema Dosvox e no programa Jogavox. As habilidades cognitivas como a memória de trabalho, a atenção e a tomada de decisão são exploradas como objetivos do estudo, bem como as dificuldades de utilização do jogo digital pela pessoa com deficiência visual. Os instrumentos de pesquisa utilizados foram a entrevista semiestruturada, o diário de bordo e as gravações da tela do computador e dos rostos dos participantes da pesquisa com o software Camtasia Studio. As informações coletadas foram agrupadas e organizadas em categorias. Foi criada uma taxonomia dos jogos digitais adaptados utilizados na pesquisa. Como resultados, identificaram-se as dificuldades de utilização dos jogos digitais adaptados e a relação desse tipo de jogo com a memória de trabalho, com a atenção e a tomada de decisão da pessoa com deficiência visual.
Actually, the school lives in an inclusive perspective, where it has to adapt the needs of all students, whether they are people with disabilities or not. The needs of each of us go beyond basic needs, we also need fun, recreation and a different education offer from the traditionally. The visually impaired person needs alternatives to the teaching-learning process and the game is an excellent alternative. Within the infinity of types of games that we find, the digital game is the one that more ascended in the last years, mainly among the young people. Today several digital games have been adapted and new digital games have been created so that the visually impaired person can use this playful tool. The digital game adapted for the visually impaired person can provide the enhancement of some existing abilities in the individual. The research consists of the study of the interaction between the student and the adapted digital games present in the Dosvox system and in the Jogavox program. Cognitive skills such as working memory, attention and decision making will be explored as goals of the study as well as difficulties in using the digital game by the visually impaired person. As research tools we used the semi-structured interview, the logbook and recordings of the computer screen and the faces of the research participants with the Camtasia Studio software. The information collected was grouped and organized into categories. A taxonomy of the adapted digital games used in the research was created. As results we identified the difficulties of using adapted digital games and the relation of this type of game to the working memory, attention and decision making of the visually impaired person.

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Souza, Edson Rufino de. "Avaliação de usabilidade do sistema Dosvox na interação de cegos com a web." Universidade do Estado do Rio de Janeiro, 2008. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=1313.

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Este relatório apresenta o desenvolvimento e os resultados de uma pesquisa sobre a usabilidade do Dosvox, sistema gratuito desenvolvido na UFRJ e utilizado por cegos no desempenho de suas tarefas com o uso de computadores, inclusive para interação com a Web. Por meio de pesquisa exploratória baseada na observação da interação de estudantes cegos com a Web, foram identificados problemas de usabilidade na interface do Dosvox e do Webvox, programa que faz parte do sistema e é utilizado no acesso a sítios eletrônicos na Web. Embora tenha havido uma grande preocupação em se desenvolver o Dosvox com foco no usuário iniciante, em entrevistas estruturadas com os desenvolvedores descobriu-se que os problemas estavam relacionados com o fato de a interface ser projetada de acordo com o modelo mental desses profissionais de Informática. Isso dificulta o seu uso por pessoas menos habituadas com estes conceitos. Somou-se a esses resultados informações encontradas na observação de cegos especialistas em acessibilidade usando o Dosvox na interação com a Web. Após a observação, foram realizadas entrevistas estruturadas, permitindo que fossem apontados outros problemas do sistema, além de caminhos de melhoria para a usabilidade do Dosvox.
This report presents development and results of a research about usability of Dosvox, free system developed in the Universidade do Estado do Rio de Janeiro (UFRJ) and used by blind people in the performance of their tasks with the use of computers, including the interaction with the Web. Through exploratory research based on the observation of the interaction of blind students with the Web, usability problems were identified in the Dosvox interface and in the Webvox, that is a program which is part of the system and is used to access the electronic sites on the Web. While there has been a major concern to develop the Dosvox with focus on novice users, structured interviews with the system developers discovered that the problems were related to the fact that the interface is designed in accordance with the mental model of these Information Technology professionals. This fact hampers its use by people less accustomed to these concepts. In addition to these results, information found on observation of blind specialists in accessibility using Dosvox in the interaction with the Web was realized. After this observation, structured interviews were conducted, an other problems in the system were highlighted, added to proposals of usability improving to Dosvox.

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Schmitz, Alexander. "Vergleich der effektiven Dosis bei CT- und durchleuchtungsgesteuerten periradikulären Injektionen." [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=976040379.

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Casteren, Marga van Klopper Lillian Schlimbach Aniek. "Over-dosis??: stralingshygiëne bij het plaatsen vanendoprothesen op de OK." Groningen : Groningen : HG, Medisch Beeldvormende en Radiotherapeutische Technieken ; Hanzehogeschool Groningen [Host], 2007. http://scripties.hanze.nl/2007/SAGZ/MBRT/11.pdf.

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Hempel, Rebecca. "Dosis und Bildqualität in der CT-Bildgebung nach HWS-Trauma." Diss., Ludwig-Maximilians-Universität München, 2014. http://nbn-resolving.de/urn:nbn:de:bvb:19-168536.

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González, Rosendo Guillermina. "Comparación de la dosis única semanal de hierro con la dosis diaria, para el tratamiento y prevención de la anemia ferropénica en mujeres adolescentes mexicanas." Doctoral thesis, Universitat Autònoma de Barcelona, 2003. http://hdl.handle.net/10803/5595.

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Objetivo: Probar la utilidad de la dosis única semanal de hierro en el tratamiento y prevención de la anemia ferropénica en mujeres adolescentes.
Metodología: Se realizó un ensayo clínico aleatorizado en paralelo, en mujeres adolescentes de 15 telesecundarias del Estado de Morelos, México. Se formaron 3 grupos de estudio en cada telesecundaria, 2 recibieron esquemas diferentes de suplementación con hierro: 1) dosis diaria; 2) dosis semanal; el tercero, de no anémicas; no recibió suplementación y fue el control. Se tomaron muestras iniciales y finales de sangre venosa a las adolescentes, a fin de determinar los valores de hemoglobina, hematocrito y colesterol. Se suplementó durante 16 semanas. Se investigaron parasitosis en heces para ajustar por éstas como un posible confusor. Se midió peso, talla, circunferencia de cintura y cadera. Adicionalmente se aplicó un formulario que contempló: aspectos dietéticos (mediante encuesta de recordatorio de 24 horas); aspectos socioeconómicos; y preguntas respecto a las características clínicas y psicológicas de la menstruación, así como de la actividad física que realizan las adolescentes.
Resultados: Participaron en el estudio 511 alumnas de educación secundaria. El 31% realizan 3 tiempos de comida y el 56% 4 y más; el 59% de las mujeres refirieron haber aumentado la cantidad de su alimentación respecto a cuando iban a la primaria. El 62% no lleva nada de comer de su casa a la escuela y el 95% compran alimentos en la escuela. El 85% de las adolescentes tiene antecedentes hereditarios de obesidad. Los valores promedio basales de las mujeres fueron: peso, 46kg (DE 8.8); talla, 151cm (DE 5.5); hemoglobina, 12.5g/dl (DE 0.6); hematocrito, 41% (DE 2.9). Los valores de hemoglobina en el grupo de suplementación diaria pasaron de 12.2 (DE 0.7) a 13.2g/dl (DE 1.0); en el grupo de suplementación semanal, se encontraron valores muy similares, de 12.2 (DE 0.7) a 13.1g/dl (DE 1.0) y en el grupo control pasó de 13.3 (DE 0.4) a 13.6g/dl (DE 1.2). En los tres grupos las diferencias fueron estadísticamente significativas (p<0.05)
Conclusiones: Las características de la muestra estudiada, son adecuadas para extrapolar los resultados a poblaciones similares. Después de las 16 semanas de suplementación hubo un comportamiento similar en los dos grupos suplementados, lo que lleva a concluir que la dosis única semanal es tan efectiva como la dosis diaria de hierro en la prevención y corrección de la deficiencia de hierro en las mujeres adolescentes. Se avanzó en el conocimiento de la prevención de la deficiencia de hierro y de la anemia ferropriva de mujeres adolescentes, mediante la utilización de dosis única semanal que reduce costos, aumenta el apego al tratamiento y mejora la absorción de hierro.
Objective: To test the utility of a single, weekly dose of iron in the treatment and prevention of anemia caused by iron deficiency in adolescent girls.
Methodology: A randomized parallel clinical study was carried out with adolescent girls from 15 secondary schools in the state of Morelos, Mexico. Three study groups were formed in each secondary school: Two received different iron supplementation schemes: 1) a daily dose 2) a weekly dose; the third, the non-anememic group, did not receive any supplementation and was the control group. Initial and final samples of antecubital vein (venous blood) were taken, in order to establish the hemoglobin, hematocrit and cholesterol levels. The supplements were administered during a period of 16 weeks. Faeces were checked for parasitosis in order to make adjustments for same as possible confounding variables. Weight, height, waist and hip measurements were taken. Additionally, a survey was carried out which contemplated the following: dietary aspects (via a 24- hour dietary recall) socioeconomic aspects and questions relating to the clinical and psychological characteristics of menstruation, as well as the physical activity carried out by the adolescent girls.
Results: 511 female secondary school students participated in the study. 31% were given 3 meals and 56% four and more; 59% of the girls claimed to have increased their daily intake of food in comparison to what they ate at primary school. 62% do not take any food to school from their home and 95% buy food at the school. 85% of the girls have a hereditary predisposition to obesity. The average basal levels of the girls were: weight, 46kg (SD 8.8); height, 151cm (SD 5.5); hemoglobin, 12.5g/dl (SD 0.6); hematocrit, 41% (SD 2.9). The hemoglobin levels in the daily supplementation group rose from 12.2 (SD 0.7) to 13.2g/dl (SD 1.0); in the weekly supplementation group very similar levels were found, from 12.2 (0.7) to 13.1g/dl (SD 1.0) and in the control group there was a rise of 13.3 (SD 0.4) to 13.6g/dl (DE 1.2). In the three groups, the differences were statistically significant (P<0.5).
Conclusions: The characteristics of the sample make it possible for the results to be extrapolated to similar sectors of the population in other communities. After 16 weeks of supplementation, there was a similar type of behaviour in the two supplementation groups, which leads to the conclusion that the single weekly dose is as effective as the daily iron dose in the prevention and correction of iron deficiency in adolescent girls. Progress was made on knowing how to prevent iron deficiency and anemia caused by iron deficiency in adolescent girls, through the use of a single weekly dose which reduces costs, increases compliance to treatment and improves the absorption of iron.

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Rickhey, Mark. "Untersuchungen zur Anwendbarkeit des inversen Monte-Carlo-Planungssystems IKO zur gezielten Dosismodulation im Tumor und deren dosimetrische Verifikation /." Regensburg, 2005. http://www.opus-bayern.de/uni-regensburg/volltexte/2009/1129/.

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Stellbrink, Elke. "Die Rolle von Dosis-Wirkungsmodellen im Rahmen von quantitativen mikrobiologischen Risikobewertungen am Beispiel des Erregers Campylobacter /." Berlin : Mbv, Mensch-und-Buch-Verl, 2009. http://d-nb.info/1000286452/04.

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Tacium, David. "Le Dandysme et la crise de l'identité masculine à la fin du XIXe siècle : Huysmans , Pater, Dos /." Thèse, Montréal : Université de Montréal, 1998. http://www.theses.umontreal.ca/theses/pilote/tacium/these.html.

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Thèse (Ph.D.)--Université de Montréal, 1998.
Mode d'accès : Web Genre de fichier informatique: Monographie électronique en format HTML. Titre de l'écran-titre (visionné le 6 nov. 2002) Disponible à partir du catalogue en ligne des thèses soutenues à l'Université de Montréal. CaQTU CaQTU

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Peleska, Gerhard. "Komplikationen der Behandlung mit Kumarin-Derivaten und Ergebnisse einer modifizierten Dosisanpassung : Pilotstudie aus einer ärztlichen Praxis /." Marburg : Görich & Weiershäuser, 2009. http://d-nb.info/994710666/04.

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Sousa, Ana Cristina de Deus e. "ENTRE MONUMENTOS E DOCUMENTOS: CIDADE DE GOIÁS, CORA CORALINA E O DOSSIÊ DE TOMBAMENTO." Pontifícia Universidade Católica de Goiás, 2009. http://localhost:8080/tede/handle/tede/2258.

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Made available in DSpace on 2016-08-10T10:34:55Z (GMT). No. of bitstreams: 1 Ana Cristina de Deus e Sousa.pdf: 5798246 bytes, checksum: d25bae7becb7f793163c7c7b25b36887 (MD5) Previous issue date: 2009-10-27
This study aims to review the document that registers the tipping of the town of Goias as World Heritage O Dossiê de Goiás, and its blatant linkage to the poet Cora Coralina, an odd character who perfectly characterizes how it is to be born and raised in Goias. Cora's poetry, while expressing the memory and identity of Vila Boa inhabitants, served as an argumentative basis in the preparation of this dossier in what concerns the town original aspects as an authentic representative of the Brazilian colonial period, and in which simplicity and ancient customs remain. The house of the poet has become a symbol of Goias. The poem which praises it more, Goiás, minha cidade, was used on the front page of the dossier in a clear demonstration of this remarkable woman s strength, as well as her power in the local culture. This written account determines the persistence of Goias over the centuries and justifies its importance for all people through the defense of its conservation and the resultant need to preserve the architectural site.
Este trabalho tem por finalidade a análise do documento de tombamento da cidade de Goiás como Patrimônio da Humanidade o Dossiê de Goiás, e sua flagrante vinculação à poetisa Cora Coralina, personagem ímpar na caracterização do jeito de ser goiano. A poesia de Cora, ao expressar a memória e a identidade vilaboenses, serviu de base argumentativa na elaboração do Dossiê quanto à originalidade da cidade como autêntica representante do período colonial brasileiro que ainda conserva a simplicidade e os hábitos de outros tempos. A casa da poetisa tornou-se um dos símbolos de Goiás. O poema que mais a exalta: Goiás, minha cidade, foi utilizado na primeira pagina do Dossiê em uma clara demonstração da força dessa mulher marcante e forte na projeção da cultura local. O Dossiê estabelece a perenidade de Goiás ao longo dos séculos e justifica sua importância para todos os povos por meio da defesa da conservação e da conseqüente necessidade de preservação do sítio arquitetônico.

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Mateus, Rodríguez Julian Andrés. "Biomarcadores del consumo de alcohol y su relación con la dosis." Doctoral thesis, Universitat Autònoma de Barcelona, 2019. http://hdl.handle.net/10803/669713.

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Introducción La detección de biomarcadores del consumo de alcohol es una herramienta útil para prevenir la aparición de problemas sociales y de salud relacionados con la ingesta del mismo. El consumo de alcohol puede monitorizarse mediante la detección de biomarcadores. En la práctica habitual se utilizan biomarcadores indirectos (volumen corpuscular medio, transaminasas, gammaglutamiltranspeptidasa o la transferrina deficiente en carbohidratos), aunque existen también biomarcadores directos del consumo de alcohol, entre ellos el propio alcohol y sus metabolitos. Entre los últimos, los biomarcadores no oxidativos del etanol como el etilglucurónido (EtG), el etilsulfato (EtS) y los ésteres etílicos de ácidos grasos (FAEEs) en diferentes matrices biológicas permiten un mejor control del consumo. En común estos metabolitos tienen una semivida de eliminación más larga que la del etanol, lo que les permite detectarse a lo largo de horas-días, según la cantidad de alcohol ingerida y el metabolito concreto. En este proyecto de Tesis se pretende conocer y realizar un estudio más completo de la relación entre la dosis de alcohol y las concentraciones de biomarcadores no oxidativos y evaluar los mismos en poblaciones específicas (adultos consumidores de bajo riesgo) y con una perspectiva de género. Métodos Se realizó un ensayo clínico de farmacocinética, en voluntarios sanos, simple ciego, no aleatorizado con una condición de tratamiento por sujeto de entre cuatro posibles, que contienen 20 g, 40 g, 60 g y 80 g de alcohol. En total participaron 53 sujetos de ambos géneros (15 para cada dosis de 20, 40 y 60 g, y 8 para la dosis de 80 g). Como criterio de inclusión los participantes debían tener un consumo de al menos 1 UBE/día (acumulada semanal) y experiencia en borracheras. Se determinaron en sangre concentraciones de etanol, etilglucurónido (EtG) y etilsulfato (EtS), y de cuatro FAEEs (palmitato, linoleato, oleato y estearato). Se determinaron en orina el EtG y el EtS. Adicionalmente, se determinaron los efectos fisiológicos, subjetivos y tolerabilidad del alcohol. Además, se determinaron las concentraciones de alcohol y sus respectivos metabolitos en plasma y orina. Los efectos fisiológicos incluyeron la medición de presión arterial, frecuencia cardíaca y temperatura oral. Los efectos subjetivos de las diferentes dosis de alcohol se evaluaron mediante cuestionarios como escalas analógicas visuales EAV, ARCI (Addiction Research Center Inventory-49 item short form, BAES (Bifasic Alcohol Effects Scale), VESSPA (Valoración de Efectos Subjetivos de Sustancias con Potencial de Abuso), y un cuestionario de identificación de dosis. Resultados Con respecto a las diferentes dosis de alcohol para los diferentes biomarcadores no oxidativos se observó que la concentración máxima (Cmax) aumentaba siguiendo una relación lineal, mientras que el área bajo la curva (AUC) dejó de ser lineal a dosis elevadas. Los periodos de detección de los biomarcadores no oxidativos fueron más prolongados que para el alcohol. Se hallaron diferencias estadísticamente significativas entre géneros en el área bajo la curva de las concentraciones de alcohol de 0 a 10h (AUC10h) siendo más alta en las mujeres que en los hombres para las 3 dosis que fueron comparadas. En la excreción urinaria del EtG y del EtS se observó que el incremento en el AUC era mayor a medida que aumentaba la dosis de alcohol, en ambos géneros, detectándose las concentraciones hasta las 48h post-administración con las dosis altas. Con respecto a los efectos subjetivos se observaron importantes diferencias interindividuales con las diferentes dosis. Conclusiones El AUC de los distintos biomarcadores no oxidativos del alcohol (FAEEs, EtG y EtS) siguió una relación no lineal con la dosis de alcohol, a diferencia de lo observado con la Cmax de la alcoholemia. Los metabolitos de los (FAEEs, Etg y Ets) en plasma se detectaron hasta las 10h post administración, mientras que en orina los metabolitos del Etg y el Ets se detectaron hasta las 48 horas. Se encontraron diferencias entre géneros tanto en las concentraciones de alcohol y metabolitos como en los efectos (generalmente superiores en las mujeres).
Introduction The detection of biomarkers of alcohol consumption is a useful tool to prevent the emergence of social and health problems related to alcohol intake. Alcohol consumption can be monitored by detecting biomarkers. Indirect biomarkers (mean corpuscular volume, transaminases, gammaglutamyltranspeptidase or carbohydrate-deficient transferrin) are used in common practice, although there are also direct biomarkers of alcohol consumption, including alcohol itself and its metabolites. The non-oxidative biomarkers of ethanol such as ethyl glucuronide (EtG), ethyl sulphate (EtS) and fatty acid ethyl esters (FAEEs) in different biological matrices provide better control of consumption. In the same way, these metabolites have a longer elimination half-life than ethanol, which can be detected along days-hours, in relation to the amount of alcohol ingested and the specific metabolite. The aim of this thesis project is to know and carry out a more complete study of the relationship between alcohol dose and non-oxidative biomarker concentrations and to evaluate these in specific populations (low-risk adult consumers) from a gender perspective. Methods A single-blind, non-randomized, pharmacokinetic clinical trial was conducted on healthy, volunteers with one treatment condition per subject between of four possible, containing 20 g, 40 g, 60 g, and 80 g of alcohol. A total of 53 subjects of both genders participated (15 for each dose of 20, 40 and 60 g, and 8 for the 80 g dose). For inclusion the participants were required to have an intake of at least 1 standar drink unit/day (accumulated weekly) and previous drunken experience. Blood concentrations of ethanol, ethyl glucuronide (EtG) and ethyl sulfate (EtS), and four FAEEs (palmitate, linoleate, oleate and stearate) were determined. EtG and EtS were determined in urine. Additionally, the physiological, subjective and tolerability effects of alcohol were determined. In addition, alcohol concentrations and their respective metabolites in plasma and urine were determined. Physiological effects included measurement of blood pressure, heart rate and oral temperature. The subjective effects of the different doses of alcohol were evaluated by several questionnaires such as visual analogue scales EAV, ARCI (Addiction Research Center Inventory-49 item short form, BAES (Bifasic Alcohol Effects Scale), VESSPA (Subjective Effects Assessment of Substances with Abuse Potential), and a dose identification questionnaire. Results It was observed that the maximum concentration (Cmax) increased following a linear relationship, while the area under the curve (AUC) was not linear at high doses. The time periods for detection of non-oxidative biomarkers were longer than for alcohol. Statistically significant gender differences were found in the area under the curve of alcohol concentrations from 0 to 10h (AUC10h) being higher in women than in men for the 3 doses that were compared. In the urinary excretion of EtG and EtS it was observed that the increase in the AUC was greater as the dose of alcohol increased, in both genders, being detected the concentrations until 48h post-administration with high doses. There were considerable differences between individuals with different doses. Conclusions The AUC of the different non-oxidative alcohol biomarkers (FAEEs, EtG and EtS) followed a non-linear relationship with the alcohol dose, in contrast to what was observed with the Cmax of alcohol. The metabolites of the (FAEEs, Etg and Ets) in plasma were detected until 10h post-administration, while in urine the metabolites of EtG and EtS were detected until 48 hours. Gender differences were found in both alcohol and metabolite concentrations and effects (generally higher in women).

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Schumacher, Kerstin. "Effekte einer reduzierten Dosis von Pflanzenschutzmitteln auf tritrophische Systeme im Ackerbau." Phd thesis, kostenfrei, 2007. http://opus.kobv.de/ubp/volltexte/2007/1567/.

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Temme, Jennifer-Kristin [Verfasser], and Georg [Akademischer Betreuer] Bauer. "Einfluss von Niedrig-Dosis-Gammastrahlung auf die Superoxidanionen-Synthese von Tumorzellen." Freiburg : Universität, 2013. http://d-nb.info/1120020492/34.

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Fischer, Frank [Verfasser], and Michael [Akademischer Betreuer] Fiederle. "Mikrocomputertomographie mit photonenprozessierenden Pixeldetektoren und iterativer Rekonstruktionsmethodik – Bildeigenschaften bei reduzierter Dosis." Freiburg : Universität, 2020. http://d-nb.info/1221061496/34.

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Leiva, Fuentes Christian Fabian. "Efecto del calcio sobre la biodisponibilidad de dosis crecientes de hierro." Tesis, Universidad de Chile, 2014. http://repositorio.uchile.cl/handle/2250/131787.

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Memoria para optar al Título Profesional de Médico Veterinario
Introducción: Se ha descrito que 800 mg de calcio (Ca) no inhiben la absorción aguda de 5 mg de hierro (Fe) (relación molar Fe:Ca, 1:223). Sin embargo, no existen evidencias sobre el efecto del Ca sobre la biodisponibilidad de Fe a mayores relaciones molares. Objetivo: Determinar el efecto de 800 mg de calcio sobre la biodisponibilidad de dosis de 5, 15, 30 y 60 mg de Fe (relaciones molares, 1:223, 1:74, 1:37 y 1:19). Metodología: Estudio experimental realizado en 13 mujeres aparentemente sanas (38 ± 4 años): En un periodo de 28 días, se suministró 5, 15, 30 and 60 mg Fe como FeSO4 (marcado con 55Fe o 59Fe) junto a 800 mg de Ca (CaCl2). Se obtuvo muestras sanguíneas a los 14 y 28 días de seguimiento, para determinar biodisponibilidad y estado de nutrición de Fe. ANOVA para muestras repetidas fue utilizada para determinar diferencias entre distintas concentraciones de Fe. Resultados: La absorción de Fe expresada en promedios geométricos (rango ± 1DE) fue de 25,5% (12,7-51,1%), 29,6% (15,9-55,1%), 22,1 % (12,3-39,8%) y 22,7% (11,8-43,6%) para dosis de 5, 15, 30 y 60 mg Fe, respectivamente (F= 1.53, N.S.). La absorción absoluta de Fe fue de 1,3; 4,4; 6,6; y 13,6 mg Fe, respectivamente. Conclusión: La administración de 800 mg de Ca no afectó la biodisponibilidad de dosis crecientes de Fe. Las concentraciones de Fe absorbidas concuerdan con valores reportados previamente al administrar 5, 50 and 100 mg Fe sin Ca (1,2; 6,7 y 13,0 mg Fe,respectivamente).
Proyecto Fondecyt 1095038

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Estévez, Gómez Javier Alejandro. "Efecto de las concentraciones de ritonavir en la farmacocinética de atazanavir: aplicación de técnicas de modelado y simulación farmacocinético poblacional." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/399998.

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Introducción: La infección por VIH se ha convertido en una enfermedad crónica debido principalmente a la introducción de la terapia antirretroviral. Atazanavir(ATV) se administra potenciado con ritonavir (RTV), siendo la dosis habitual 300mg de ATV y 100mg de RTV una vez al día, aunque también se puede administrar sin potenciar. Actualmente la simplificación de los tratamientos antirretrovirales es uno de los objetivos más importantes para facilitar el cumplimiento de la terapia y evitar el fallo terapéutico. Hipótesis general: Se pueden optimizar los regímenes de atazanavir recomendados actualmente. Objetivos: Evaluar diferentes regímenes de dosificación de atazanavir comparando sus concentraciones con las de los regímenes aprobados por las agencias regulatorias. Estudio "in vivo": Evaluar la farmacocinética, tolerabilidad y seguridad de 300mg de ATV potenciado con 100mg o 50mg de RTV, administrado una vez al día, en el estado de equilibrio estacionario. Estudio "In numero": Desarrollar un modelo farmacocinético poblacional simultáneo que incorpore el efecto de RTV en el aclaramiento de ATV y predecir las concentraciones de ATV en diferentes regímenes de dosificación en pacientes infectados por el VIH-1. Métodos: Estudio "in vivo": Estudio prospectivo, simple-ciego, de dosis múltiples, cruzado y aleatorizado. Trece hombres sanos VIH-1-negativos recibieron ATV (300mg) y RTV 100mg o 50mg durante 10 días (15 días de lavado). A día 10 se determinaron las concentraciones plasmáticas de ATV y RTV durante 24h. Se compararon los parámetros farmacocinéticos individuales log-transformados entre tratamientos y se calculó la diferencia entre los mismos en escala logarítmica y los intervalos de confianza del 95%. Se midieron y compararon los niveles de colesterol total y LDL, triglicéridos, glucosa y bilirrubina al inicio y al final de cada período(Wilcoxon-rank test). Se registraron los acontecimientos adversos. Estudio "in numero": Estudio transversal que incluyó 83 adultos VIH-1+ tratados con ATV 400mg o ATV 300mg/RTV 100mg una vez al día. Se determinaron las concentraciones en plasma de ambos fármacos. Se construyó un modelo farmacocinético y se simularon seis escenarios de dosificación utilizando la aproximación poblacional no lineal de efectos mixtos. Resultados: Estudio "in vivo": La Cmax y AUC0-24 de RTV fueron menores tras 50mg que 100mg (ratio de media geométrica [GMR 95% intervalo de confianza], 0.40 [0.31-0.51] y 0.35 [0.29-0.42], respectivamente). No se observaron diferencias en la exposición a ATV con RTV 50mg o 100mg (GMR, Cmax, 1.00[0.79-1.28]; AUC0-24, 0.98 [0.79-1.21]). La concentración valle de ATV fue >0.15mg/L en todos los voluntarios. El colesterol total y LDL aumentaron 0.40 mmol /L (p = 0.01) y 0.37 mmol/L (p = 0.003) respectivamente en el período RTV 100mg; no hubo cambios significativos en el período RTV 50mg. Al décimo día la bilirrubina aumentó levemente pero sin diferencias entre los tratamientos. Estudio "in numero": Un modelo monocompartimental simultáneo describió la farmacocinética de RTV y ATV, mostrando una inhibición exponencial directa de RTV en el aclaramiento de ATV, lo que explicó el 17.5% de la variabilidad. Una concentración media de RTV=0.63 mg/L predice un 18% de disminución en el aclaramiento de ATV. El porcentaje de pacientes simulados con concentraciones de ATV al final de intervalo posológico fuera del rango 0.15-0.85mg/L favorece los regímenes de una vez al día (ATV 400mg, ATV 300mg/RTV 100mg, ATV 300mg/RTV 50mg, ATV 200/RTV 100mg) con respecto a los regímenes de dos veces al día no potenciados (ATV 300mg, ATV 200mg). Conclusiones: Ambos estudios sugieren que una reducción en la dosis de potenciación de ritonavir de 100 a 50mg beneficiaría a los pacientes disminuyendo la incidencia de eventos adversos sin disminuir la exposición a ATV. Además, el estudio "in numero" favorece la bajada de la dosis de ATV a 200mg potenciada con 100mg de RTV.
Introduction: HIV infection has become a chronic and manageable condition mainly due to the successful introduction of triple antiretroviral therapy. Atazanavir(ATV) is a protease inhibitor, with a good lipid profile and high genetic barrier, but undergoes first pass metabolism, which causes low bioavailability. Because of that, atazanavir is usually boosted with ritonavir (RTV), a CYP3A4 inhibitor, being the standard dose: ATV 300mg/RTV 100mg once a day, although ATV can also be administered unboosted. Simplification of antiretroviral treatment is currently one of the most important objectives to facilitate therapy compliance and avoid treatment failure. General hypothesis: ATV actual dose regimens can be optimized. Objectives: To evaluate different dose regimens of atazanavir and compare their concentrations with those from the approved by the regulatory agencies. "in vivo" study: To evaluate the pharmacokinetics, tolerability, and safety of ATV 300mg boosted with RTV 100mg or 50mg, both once-daily, at steady-state. "in numero" study: To develop a simultaneous population pharmacokinetic model for ATV incorporating the effect of RTV on clearance to predict ATV concentrations under different dosing regimens in HIV-1-infected patients. Methods: "in vivo" study: This was a single-blind, multiple-dose, crossover, sequence-randomized trial. Thirteen healthy HIV-1-negative men received witnessed once-daily doses of ATV (300mg) and RTV 100mg or 50mg for 10 days (15-day washout). ATV and RTV plasma concentrations were determined for 24h on day 10. Log-transformed individual pharmacokinetic parameters were compared between treatments (analysis of variance); the difference between treatments on the log-scale and 95% confidence intervals were calculated. Fasting cholesterol, triglycerides, glucose and bilirubin plasma levels were measured at the beginning and end of each period and compared (Wilcoxon signed-rank test). Adverse events were recorded. "in numero" study: A cross-sectional study was carried out in 83 HIV-1-infected adults taking ATV 400mg or ATV 300mg/RTV 100mg both once daily. Demographic and clinical characteristics were registered and blood samples collected to measure drug concentrations. A population pharmacokinetic model was constructed using nonlinear mixed-effects modeling and used to simulate six dosing scenarios. Results: "in vivo" study: RTV Cmax and AUC0-24 were lower after the 50-mg booster dose than after 100mg (geometric mean ratio [GMR 95% confidence interval], 0.40 [0.31–0.51] and 0.35 [0.29–0.42], respectively). No differences were observed in ATV exposure with RTV 50 or 100mg (GMR, Cmax, 1.00 [0.79–1.28]; AUC0-24, 0.98 [0.79–1.21]). ATV trough concentration was >0.15 mg/L in all volunteers. Total and LDL cholesterol increased 0.40 mmol/L (p=0.01) and 0.37 mmol/L (p=0.003) in the 100mg period; there were no significant changes on 50mg. Mild increases in bilirubin were detected on day 10 after both treatments without differences between treatments. "in numero" study: A one-compartmental model described the pharmacokinetics of RTV and ATV simultaneously, showing exponential, direct inhibition of ATV clearance according to the RTV plasma concentration, which explained 17.5% of the variability. A mean RTV plasma concentration of 0.63 mg/L predicted an 18% decrease in ATV clearance. The percentages of patients with an end-of-dose-interval concentration of ATV below or above the minimum and maximum target concentrations of 0.15 mg/L and 0.85mg/L favored the selection of the simulated once-daily regimens (ATV 400mg, ATV 300mg/RTV 100mg, ATV 300mg/RTV 50mg, ATV 200mg/RTV 100mg) over the unboosted twice-daily regimens (ATV 300mg, ATV 200mg). Conclusions: The "in vivo" and "in numero" studies suggest that a reduction in RTV boosting dose from 100mg to 50mg would benefit the patients as the adverse events would decrease without decreasing atazanavir exposure. However, the "in numero" study favours the reduction in atazanavir to 200mg once daily boosted with 100mg of RTV.

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Turci, Paulo Cesar. "Softwares de acessibilidade Dosvox e Virtual vision: um programa de ensino ao aluno com cegueira." Universidade Federal de São Carlos, 2013. https://repositorio.ufscar.br/handle/ufscar/3132.

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Universidade Federal de Sao Carlos
Dosvox and Virtual Vision accessibility software are screen reader programs that allow reading of the information presented on computer screens through speech output using voice synthesis technology, making their use possible by people with blindness. The objective of this study was to implement and evaluate the effectiveness of a teaching program for the use of accessibility software Dosvox and Virtual Vision by students with blindness of elementary and middle school. To this end, we developed a quasiexperimental study with an AB design, attended by two students with blindness, 18 and 19 years old, who were attending the sixth grade of elementary school and the third year of middle school, respectively. Both attended the same Resource Room facility featured by a public school located within the countryside of the State of São Paulo. The Education Program was 30 hours long, with one hour weekly classes. The following tools have been used to collect data: a) A semi-structured interview, applied preintervention to check the suitability of participants to the inclusion criteria of the study and characterize them. b) The tasks protocol has been used to measure participants' knowledge at two different times: 1) before the education program had been applied (pre-intervention) and 2) after the education program was implemented (postintervention). c) Questionnaire to measure participants' satisfaction. d) Field diary to record the development of the education program. The analysis and interpretation of data was quantitative and qualitative: a) Quantitative evaluation of data from protocol tasks. b) Qualitative evaluation of data from semi-structured interview, from questionnaire and from the field diary. The results obtained in quantitative evaluation showed that performance of the first participant was better than that of the second participant. The qualitative evaluation has shown that the education program was effective for developing flexible teaching strategies that allowed participant 1, who had no computer and had no prior knowledge about the software, a great level of knowledge acquisition. Participant 2, who had a computer and prior knowledge about the software, was enabled to improve his technique so that now he performs numerous tasks with excellence. By making both of them able to use Microsoft Word and access the virtual environments with a computer equipped with Dosvox or Virtual Vision, the new pedagogical strategies arising from the use of computers in the classroom promoted the transition of the educational process of participant 2, previously marked by the demerit of his intellectual capacity, failure and assistance, to a new reality guided by equality and sharing with his peers. No considerations were made about the educational process of participant 1 due to the absence of a computer in the classroom where he had been studying.
Os softwares de acessibilidade Dosvox e Virtual Vision são programas chamados leitores de telas que através da tecnologia de síntese de vozes permitem a leitura das informações apresentadas na tela do computador, tornando possível seu uso pelas pessoas com cegueira. O objetivo do presente estudo foi aplicar e avaliar a eficácia de um programa de ensino para o uso dos softwares de acessibilidade Dosvox e Virtual Vision por alunos com cegueira do ensino fundamental e médio. Para tanto, foi desenvolvido um estudo quase experimental com delineamento AB, do qual participaram dois alunos com cegueira, com 18 e 19 anos, que estavam cursando a sexta série do ensino fundamental e o terceiro ano do ensino médio, respectivamente. Ambos frequentavam a mesma sala de recursos de uma escola pública localizada no interior do Estado de São Paulo. O programa teve 30 horas de duração, com aulas semanais de uma hora. Para a coleta de dados foram utilizados os seguintes instrumentos: a) Entrevista semiestruturada, aplicada pré-intervenção, para verificar a adequação dos alunos aos critérios de participação da pesquisa. b) protocolo de tarefas para mensurar os conhecimentos dos participantes em dois momentos diferentes: 1) antes do programa de ensino ser aplicado (pré-intervenção) e 2) depois do programa de ensino aplicado (pósintervenção). c) Questionário para mensurar a satisfação dos participantes. d) Diário de campo para registrar o desenvolvimento do programa. A análise e interpretação dos dados foi quantitativa e qualitativa; a) quantitativa: dos dados do protocolo de tarefas e b) qualitativa: dos dados da entrevista semiestruturada, do questionário e do diário de campo. Os resultados aferidos na avaliação quantitativa evidenciaram que o desempenho do participante 1 foi melhor do que o do participante 2. A avaliação qualitativa demonstrou que o programa de ensino foi eficaz, por ter desenvolvido estratégias pedagógicas flexíveis que possibilitaram ao participante 1, que não possuía computador e não tinha conhecimentos prévios sobre os softwares, um ótimo nível de aquisição de conhecimentos. Ao participante 2, que tinha um computador e conhecimentos prévios, possibilitou aprimorar sua técnica de tal forma que passou a realizar inúmeras tarefas com excelência, tornando ambos aptos a usar o Microsoft Word e acessar os ambientes virtuais com um computador equipado com o Dosvox ou Virtual Vision. As novas estratégias pedagógicas originadas pelo uso do computador na sala de aula promoveram a transição do processo educacional do participante 2, anteriormente marcado pelo demérito de sua capacidade intelectual, fracasso e assistencialismo, para uma nova realidade pautada pela igualdade e o compartilhamento com seus pares. Não foram realizadas considerações sobre o processo educacional do participante 1 em decorrência da ausência do computador na sala de aula em que ele estudava.

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Aceves, Solano Jacqueline Yuliana, and Soto Francisco Urias. "“ESTUDIO COMPARATIVO DE LA TERAPIA HORMONAL DE REEMPLAZO DOSIS BAJAS VERSUS DOSIS ESTÁNDAR Y SUS EFECTOS EN LA SINTOMATOLOGIA CLIMATERICA DE ACUERDO A LA ESCALA MENOPAUSE RAITING SCALE"." Tesis de Licenciatura, Medicina-Quimica, 2014. http://ri.uaemex.mx/handle/123456789/14684.

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Finestres, Zubeldia Fernando. "Tratamiento del cáncer de labio mediante braquiterapia de alta tasa de dosis." Doctoral thesis, Universitat de Barcelona, 2003. http://hdl.handle.net/10803/1176.

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OBJETIVOS: Valorar la utilidad del tratamiento en estadios I y II de cáncer de labio mediante braquiterapia de alta tasa de dosis (ATD) y el empleo de nuevos aplicadores cutáneos. Establecer la eficacia y morbilidad de las dosis terapéuticas administradas
MATERIAL Y MÉTODOS: Desde febrero de 1992 hasta diciembre de 2000, fecha en que se cierra el estudio, un total de 56 pacientes con cáncer de labio (49 T1N0M0 y 7 T2N0M0) han sido tratados mediante braquiterapia de ATD con moldes personalizados desde la superficie cutánea. La dosis mínima en el tumor fue de 6000 a 7000 cGy aplicada en 33 a 38 fracciones a 180 cGy/fracción.
RESULTADOS: Mediante los moldes personalizados se logró una distribución de la dosis uniforme en la superficie del labio y a 5 mm de profundidad correspondiente al área del aplicador. A esta profundidad, las diferencias entre las zonas de máxima y mínima dosis nunca alcanzaron valores superiores al 5% de la dosis prescrita. Dado el gradiente de dosis, a 5 mm de la periferia de los aplicadores la dosis detectada fue despreciable. En todos los pacientes se produjo una remisión completa del tumor. La supervivencia libre de enfermedad (SLE) fue determinada mediante el método de Kaplan-Meier y permaneció invariable en el 96% a partir del primer año de seguimiento hasta el final del estudio pues en el octavo y décimo mes postratamiento se detectaron dos casos de metástasis ganglionar que fueron tratados con cirugía selectiva sin volver a aparecer en ningún caso más enfermedad metastásica ni recidiva local. La tolerancia al tratamiento fue excelente en todos los casos. No hubo complicaciones severas inmediatas ni tardías al tratamiento y el grado de estética y función fue bueno o excelente en 55 de 56 casos.
CONCLUSIONES: 1º) La eficacia del tratamiento ha resultado buena o excelente pues: a) Se ha obtenido un completo control local del tumor; b) La SLE fue del 96,5% a los 3 años de seguimiento, con 2 únicos casos de metástasis ganglionares dentro del primer año de seguimiento; c) De los pacientes fallecidos antes de llegar al final del estudio, ninguno lo hizo por causa atribuíble a su cáncer de labio. 2º) La pauta administrada ha resultado eficaz y bien tolerada (180 cGyfracción 5dias/semana hasta 60-70 Gy). 3º) Los nuevos moldes han resultados cómodos, seguros y reproducible su posición en cada fracción administrada. 4º) El grado de estética y función ha sido bueno o excelente en todos los casos excepto uno, con resultado estético regular.

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Müller-Friedl, Helmut. "Zum Einfluss der Dexamethason-Dosis auf Chemotherapie-induzierte akute Nausea und Emesis." [S.l.] : [s.n.], 1999. http://deposit.ddb.de/cgi-bin/dokserv?idn=960059490.

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Haj-Houssain, Samer. "DOSIS un serveur OSI pour l'ouverture des systèmes distribués au monde extérieur /." Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb376142003.

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Haj, Houssain Samer Mazaré Guy Mossière Jacques. "DOSIS un serveur OSI pour l'ouverture des systèmes distribués au monde extérieur /." S.l. : Université Grenoble 1, 2008. http://tel.archives-ouvertes.fr/tel-00328632.

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Kleyer, Oskar, and Fredrik Holmlund. "Dosis: din smarta pillerdosa : Utveckling av ett inbyggt system för en dosettask." Thesis, KTH, Hälsoinformatik och logistik, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-230648.

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Modern medicinering medför att patienter kan behandlas mer effektivt om den tas pårätt sätt. När patienter själva ansvarar för sin medicinering kan den feldoseras ellerglömmas bort, vilket ändrar förutsättningar för dess inverkan. Glömska kombineradmed sinnesnedsättningar försvårar för patienten att sköta sin medicinering.Lösningen på detta problem är idag utökad hemvård där vårdpersonal hjälper patientenatt ta rätt medicin vid rätt tidpunkt. En teknisk lösning kan vara ett inbyggt systemsom påminner patienten, sparar missade doseringar och kan därmed ge mer informationtill läkare som då kan göra mer välgrundade beslut för fortsatt vård.Resultaten visar att en dosettask kan användas för att påminna patienter att ta sinmedicin och skicka missad dosering med närfältskommunikation. Som mikrokontrolleranvändes en STM32 Nucleo, med en tillståndsmaskin som mjukvarulösning. I vidarestudier kan ett realtidsoperativsystem användas. Systemet programmerades medArduinos utvecklingsmiljö, men ett alternativ är IAR. Projektets prototyp kunde medde flesta modulerna uppnå specifikationens batteritid, utöver ljudmodulen som användes.För att komma fram till detta resultat skapades två teoretiska extremfall därprototypen testades.Dosettasken kan leda till minskat pillersvinn och en lägre kostnad då färre hembesökkrävs. Dessutom resulterar detta i ökad självständighet för patienten. Dessa faktorerleder till att dosettasken bidrar till en ökad hållbar utveckling.
Modern medication allows patients to be treated more efficiently if taken properly.When patients themselves are responsible for their medication, it can be wronglydosed or forgotten, which changes the conditions for its effects. Forgetfulness combinedwith impaired senses make it difficult for the patient to take care of his medication.The solution to this problem today is increased home care, where healthcare professionalshelp patients to take the right medication at the right time. A technical solutioncan be an embedded system that reminds the patient, saves missed dosages, and canprovide more information to doctors who can make more informed decisions for furthercare.The results show that a pill dispenser can be used to remind patients to take their medicationand send missed dosages with near field communication. As a microcontroller,a STM32 Nucleo was used, with a state machine as software solution. In further studies,a real-time operating system can be used. The system was programmed with Arduino'sdevelopment environment, but an alternative is IAR. The prototype of the projectcould achieve the specifications battery life with most modules, except to thesound module used. To achieve this result, two theoretical extremes were created inwhich the prototype was tested.The pill dispenser can lead to reduced waste of pills and a lower cost, as fewer homevisits are required. In addition, this results in increased independence for the patient.These factors cause the pill dispenser to contribute to increased sustainable development.

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Haj, Houssain Samer. "Dosis : un serveur OSI pour l'ouverture des systèmes distribués au monde extérieur." Grenoble INPG, 1988. http://tel.archives-ouvertes.fr/tel-00328632/.

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L'ouverture de ces systèmes est assurée au moyen d'un service de communication externe. Ce service permet aux applications s'exécutant dans le système distribue local de communiquer à plusieurs niveaux de protocoles avec d'autres applications s'exécutant sur des systèmes distants distribues ou centralises. On étudie l'architecture et le fonctionnement de tels systèmes

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Magino, Relaiza Jakeline Del Pilar. "Revisión crítica : omisión de dosis en administración de medicamentos en enfermeras emergencistas." Bachelor's thesis, Universidad Católica Santo Toribio de Mogrovejo, 2019. http://hdl.handle.net/20.500.12423/2303.

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Esta revisión crítica: Omisión de Dosis en Administracion de Medicamentos en Enfermeras Emergencistas, tuvo como objetivo identificar los factores que contribuyen a la omisión de dosis en la administración de medicamentos por parte del personal de Enfermería del servicio de emergencias. Cuya importancia es el cuidado, se ve afectado por múltiples errores y/o factores condicionantes perjudicando de tal forma la calidad de la atención. La Investigación Secundaria se abordara con la metodología: EBE y sus 5 fases, nos permitirá localizar la necesidad clínica afectada, cuya pregunta es: ¿Cuáles son los factores que contribuyen a la omisión de dosis en la Administración de Medicamentos de las Enfermeras del servicio de Emergencias?, utilizando la base de datos: Ciberindex, Google Académico, Proquest y Epistemonikos y palabras claves, seleccionando 10 investigaciones primarias. La metodología y diseño de la investigación, fueron evaluados por la Guía de Validez y Utilidad de Gálvez Toro de las cuales solo 1 paso el filtro, la investigación de Silvia González Gómez y de acuerdo al diseño y metodología usada, se ha estructurado el comentario crítico, trabajando con la lista de chequeo de Astete.Los factores que contribuyen a la omisión de dosis en la Administración de Medicamentos de las Enfermeras del servicio de Emergencias, son el turno laboral donde el 47% son del turno mañana, la antigüedad laboral con un 35.3% con una franja de 1-5 años, tipo de contrato con 35.6% en personal eventual.

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Ortíz, Martínez Jorge José. "Calidad de Analgesia Postoperatria con Morfina Intratecal a diferentes dosis en Cesárea." Tesis de Licenciatura, Medicina-Quimica, 2013. http://ri.uaemex.mx/handle/20.500.11799/13823.

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La morfina intratecal es una excelente elección para prevenir o tratar el dolor post cesárea en las pacientes que reciben anestesia subaracnoidea. Dosis de 50, 100 hasta 200 μg se han recomendado en las mujeres Caucásicas, sin estar exentas de efectos secundarios asociados al uso de opioides subaracnoideos. Objetivo. El motivo de este estudio fue evaluar la seguridad, eficacia analgésica y efectos secundarios de dos diferentes dosis de morfina intratecal para analgesia post cesárea en embarazadas del Hospital General Ecatepec “Las Américas”. Material y Método. El estudio fue realizado en el Hospital General de Ecatepec “Las Américas”. Ensayo clínico controlado, aleatorizado, doble ciego. Después de que el Comité de Ética e Investigación revisó y aprobó el protocolo y las pacientes firmaron su consentimiento informado, se les inyectaron 50 o 100 μg de morfina intratecal mas bupivacaína isobárica 0.5%. Se evaluó la analgesia y los efectos secundarios durante 24 horas post bloqueo. La analgesia de rescate se hizo con Ketorolaco, metamizol y tramadol. Resultados. La analgesia fue efectiva en ambos grupos, y los requerimientos de analgesia de rescate fueron mínimos durante 24 horas. La analgesia de rescate fue similar en ambos grupos sin significancia estadística. Los efectos secundarios no tuvieron diferencia estadística significativa, aunque si existió diferencia clínica, mostrándose menores efectos secundarios con el uso de 50μg de morfina. Conclusiones. La dosis de 50 μg y 100 μg de morfina subaracnoidea fueron efectivas para aliviar el dolor después de operación cesárea durante 24 horas después de administrada. Los efectos secundarios indeseables fueron estadísticamente más frecuentes en el grupo que recibió la dosis más grande. La analgesia de rescate se requirió por igual en ambos grupos. Se sugiere que se usen dosis de 50 μg de morfina intratecal para analgesia post cesárea en las pacientes sometidas a anestesia subaracnoidea.

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Espinoza, Vargas Milagros María Esther, and Huamaní Ana Meida Hualpa. "Evaluación de la calidad de Intubación con tres diferentes dosis de rocunario." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2002. https://hdl.handle.net/20.500.12672/2059.

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Introducción: las condiciones de intubación con rocuronio varían de acuerdo a la dosis administrada, pudiendo lograrse proporciones diferentes de condiciones adecuadas o inadecuadas. Se investigaron los efectos de 1 DE95, 2 DE95 y >3DE95. Objetivos: comparar las condiciones de intubación con diferentes dosis de rocuronio en pacientes programados para cirugía electiva. Material y métodos: se empleó una escala de valoración de la relajación muscular, la escala de Domaoal para poder comparar los resultados. Los operadores completaron una ficha de reporte sobre las condiciones de intubación para poder hacer las comparaciones. Resultados: la comparación entre los valores en la escala de Domaoal, clasificación de Cormack-Lehane, escala de Adnet y tiempo de intubación de los pacientes tratados con diferentes dosis de rocuronio sometidos a intubación endotraqueal demostró la existencia de diferencia significativa. Conclusiones: con el empleo de rocuronio se logra condiciones de intubaciones buenas y excelentes en pacientes medicados con dosis 2DE95 o más. El empleo de 1 DE95 está asociado a un porcentaje significativamente incrementado de condiciones de intubación inadecuadas.
Tesis de segunda especialidad

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Berré, Alessio. "Alle origini del «romanzo giudiziario» italiano : la figura del delinquente tra letteratura, Diritto e scienze mediche." Thesis, Paris 10, 2014. http://www.theses.fr/2014PA100038.

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Cette thèse de doctorat a pour objectif d’interroger les relations entre littérature, droit et sciences médicales à l’intérieur de ce qu’on appelle le roman « judiciaire », genre qui s’est développé en Italie dans une période comprise entre l’Unité nationale et le tout début du XXème siècle. Dans ce cadre, nous nous questionnons essentiellement sur l’élément principal qui émerge de cette relation interdisciplinaire, à savoir la construction de la figure du criminel. Dans cette perspective, nous avons pu en effet dégager que la construction de cette figure est centrale dans de nombreux romans de la période post-unitaire. En nous concentrant ensuite sur la notion de genre, nous nous sommes départis de la querelle désormais séculaire inhérente à la naissance (voire à l’existence même) du roman policier italien. Notre analyse souligne enfin que c’est dans la relation entre littérature, droit et sciences médicales que se révèle toute la valeur de ces romans judiciaires dans le processus de construction de l’identité nationale italienne.Notre travail est composé de deux parties. La première, à caractère historique, entend proposer une nouvelle définition du genre dit « judiciaire », après avoir examiné avec attention, et parfois révoqué en doute, les hypothèses avancées jusqu’à nos jours, sur le sujet, par la critique. La seconde partie s’appuie sur deux cas spécifiques – Colonia felice de C. Dossi et Romanzo di Misdea de E. Scarfoglio – qui nous ont permis d’étudier la composition des différentes figures du criminel, attestant de l’efficacité de la méthode interdisciplinaire adoptée, et en portant une attention toute particulière aux théories de Cesare Lombroso
This doctoral thesis aims to investigate the relations between literature, law, and medicine in the so-called “legal novel”—a genre that has developed in Italy between the national unification and the very beginning of the 20th century. My discussion examines the centrepiece of this interdisciplinary connection—namely, the literary construction of the figure of the criminal. Through this argument I show that the characterization of the criminal is central to several novels of the period following the unification. Turning then to the notion of genre, my thesis considers the long-standing debate surrounding the origins (and the existence itself) of the Italian detective novel. Finally, I suggest that the intersection between literature, law, and medicine sheds an important light on the role played by the legal novel in the construction of Italian national identity.My study falls into two parts. The first section is historical; it seeks to offer a new definition of the “legal” novelistic genre, building on—and partially questioning—the existing literature on the topic. The second part centres on two case studies, C. Dossi’s Colonia felice and E. Scarfoglio’s Romanzo di Misdea. These close readings enable me to further examine the characterization of different criminal figures, demonstrating the fruitfulness of this interdisciplinary methodology while placing a particular emphasis on Cesare Lombroso’s theories

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Ceconi, Denise Ester. "Dossiê de ambiência e transição agroecológica no manejo da microbacia hidrográfica do lajeado Biguá, Alecrim - RS." Universidade Federal de Santa Maria, 2007. http://repositorio.ufsm.br/handle/1/5583.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
The atrophic disordinated action over an area leads to degradation of the natural resources, mainly the soil, water and native vegetation, changing the landscape, altering the ambience and bringing negative consequences to the social and economical conditions of the population. In such context, the current study had as its aims assess, through an ambience dossier, the physical-conservationist, social-economical and environmental degradation, giving priority to recuperation goals, as well as carry on a floristic survey of the riparian vegetation aiming, its recovering and a case study in family agro ecological system as an alternative way of management in the Watershed of Lajeado Biguá, Alecrim - RS. The ambiance dossier was carried on through observations and interviews with farmers of the studied micro basin. The floristic survey was done in randomly demarcated parcels along the banks of the Lajeado Biguá stream, where arboreal, herbaceous and shrub strata were sampled. In the agro ecological case study, a history of the property use was done, the current soil status was assessed and samples of the soil were taken in order to assess it main chemical and physical characteristics. The dossier results show that, among the main problems, the ones inherent to soil and water degradation stand out, mainly due to the inadequate management of this natural resources. The main cause of degradation is the soil preparation in a conventional way and the soil use in areas which should be of permanent reservation, as banks of rivers and steep areas. The degradation of riparian vegetation was caused by the use of the bank soil with crops and grazing, affecting the stream water quality and quantity and the water sources used by the population, as well as the riparian vegetation species and their natural regeneration capability. The riparian vegetation recover with the use of the species found in the floristic survey is recommended aiming its functions reestablishment. The agro ecology seems to be a viable system, mainly for small rural property, offering good productivity, crop diversification, healthy products, with higher demand and value-added smaller cost production with higher income to the producer, therefore increasing his/her social and economical conditions, being and alternative to the agricultural system in the studied micro basin. However, conservationist management ways are recommended, such as no-tillage, aiming the improvement of the chemical and physical soil characteristics, mainly the support of organic matter, which is the most affected by the conventional preparation used in the area studied and all over the watershed.
A ação antrópica desordenada sobre uma área leva à degradação dos recursos naturais, principalmente do solo, da água e da vegetação nativa, modificando a paisagem, alterando a ambiência e trazendo conseqüências negativas às condições sócio-econômicas da população. Neste contexto o presente estudo teve como objetivos avaliar através de um dossiê de ambiência a degradação físico-conservacionista, sócio-econômica e ambiental, priorizando metas de recuperação, bem como realizar um levantamento florístico da vegetação ciliar visando sua recuperação e um estudo de caso em sistema familiar agroecológico como forma alternativa de manejo na Microbacia Hidrográfica do Lajeado Biguá, Alecrim - RS. O dossiê de ambiência foi realizado através de observações in loco e de entrevistas com os agricultores da microbacia estudada. O levantamento florístico foi realizado em parcelas demarcadas aleatoriamente ao longo das margens do arroio Lajeado Biguá, onde se amostrou os estratos arbóreo, arbustivo e herbáceo. No estudo de caso agroecológico realizou-se um histórico de uso da propriedade, avaliou-se o uso atual dos solos e coletou-se amostras de solo para avaliar suas principais características químicas e físicas. Os resultados do dossiê mostram que, entre os principais problemas, destacam-se os inerentes a degradação do solo e da água, devido principalmente, ao manejo inadequado destes recursos naturais. A principal causa de degradação é o preparo do solo de forma convencional e o uso do solo em áreas que deveriam ser de preservação permanente, como margens de rios e áreas com declividade muito acentuada. A degradação da mata ciliar foi ocasionada pelo uso do solo das margens com lavouras e pastagens, afetando a qualidade e quantidade de água do arroio e das fontes usadas pela população, bem como as espécies da vegetação ciliar e a capacidade de regeneração natural destas. Recomenda-se uma recuperação da mata ciliar com o uso das espécies encontradas no levantamento florístico, visando restabelecer as funções desta. A agroecologia apresentou-se como um sistema agrícola viável, principalmente para a pequena propriedade rural, fornecendo boa produtividade, diversificação de culturas, produtos saudáveis, com maior procura e valor agregado, menor custo de produção e maior renda para o agricultor, melhorando assim suas condições sócio-econômicas, podendo ser indicada como alternativa de sistema agrícola na microbacia estudada. Entretanto, recomenda-se o uso de formas de manejo conservacionistas, como o plantio direto, visando melhorar as características químicas e físicas do solo, principalmente o aporte de matéria orgânica, que é o mais afetado pelo preparo convencional adotado na propriedade estudada e em toda microbacia.

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Dissertations / Theses on the topic 'Dosvit'

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