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Dissertations / Theses on the topic 'Dotlak'

Author: Grafiati

Published: 28 June 2021

Last updated: 29 July 2025

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1

Havel, Jiří. "Hodnocení porezity u tlakově litých odlitků z Al slitin." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2012. http://www.nusl.cz/ntk/nusl-230266.

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The aim of this diploma thesis is to analyse the porosity of die - cast cast that were made of the alloy AISi9u3 in iron-foundry Skoda Car Mlada Boleslav. The analysis and the sample comparisons are based on my own measurements and are also connected with previous diploma thesis which deals with that issue and was drawn up at Technical University in Brno. All measurements were statistically tested.

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Lefner, Jiří. "Hodnocení mechanických a strukturních vlastností nového bloku." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2009. http://www.nusl.cz/ntk/nusl-228721.

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The purpose of this dilploma thesis is to evaluate mechanical and structural properties of two types casts of Al-alloy (components of the engine block) which were made by different technologies. Die casting with local squeeze casting and without local squeeze casting. First of them is used in lot manufacture of the current engine block. The aim of the foundry is to change the technology and start to produce new block by the die casting without local squeeze casting. The samples were taken from the both parts (lower and upper part) of the current and the new engine block which are made in found

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3

Khamzin, Yersin. "Technologie vstřikování zkušebních těles z termoplastů." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2021. http://www.nusl.cz/ntk/nusl-444217.

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The diploma thesis focuses on the optimization of technological parameters of plastic injection molding and the study of the influence of technological parameters on the quality of molded test specimens’ type 1A. The quality of molded parts for 3 types of polypropylene (PP) with different melt flow rate (Mosten GB 002, Mosten GB 218, Mosten MA 230) and 1 type of polystyrene (PS) (Krasten PS GP 154) was evaluated in terms of dimensional stability and weight. The contribution of software for modeling the plastic injection molding process was evaluated in this work. SOLIDWORKS Plastics software w

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4

Lewis, W. Charles. "Selected ministry factors that may contribute to the interracial status of Dothan Community Church a case study /." Online full text .pdf document, available to Fuller patrons only, 2000. http://www.tren.com.

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5

Svenblad, Hampus, and Josefin Bengtsson. "Ideation through visualization : – The use of Storyboard as a preparing tool." Thesis, Mälardalens högskola, Akademin för innovation, design och teknik, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-24270.

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Problem Ideation in group is used by many, often as a tool for creating new and innovative ways to solve problems and creating change. Groups may have difficulties to move from the phase of inspiration to the phase of ideation, if information and ideas aren’t defined in the team. The authors claim that this process can be helped by providing practical tools that are adapted and tested for the purpose. The reason is to foster concretization of volatile thoughts in form of inspiration and information. Purpose The study aims to investigate how Storyboard as a tool can be used to concretize though

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Cockerham, Catherine L. "Burial practice at Tell Dothan was Tomb 1 a "byt mrzḥ"? /." Theological Research Exchange Network (TREN), 1995. http://www.tren.com.

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7

Bengtsson, Linda. "Spin-coatade dispersioner på glasytor : en studie av aggregationen mellan latex och DoTAB med AFM." Thesis, Karlstads universitet, Fakulteten för teknik- och naturvetenskap, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-14568.

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8

Zhou, Chan Dante. "Reputación del streamer peruano de Dota 2: la perspectiva del jugador de Dota 2 peruano." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/654794.

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La industria gamer ha llevado a la posibilidad de subsistir económicamente del streaming. Dado que los streamers generan ingresos en relación con su audiencia, mientras mayor sea esta y esté más conectada con ella mayor probabilidad habrá de que genere mayores ingresos. Por ende, surge un nuevo modelo de negocio que requiere de una gestión reputacional para construir esta audiencia. Para ello, se necesita un primer análisis del contexto peruano desde la percepción que mantienen los jugadores de Dota 2 peruanos frente a los streamers peruanos de Dota 2. Por ello, este trabajo utiliza el paradig

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9

VARGAS, GARCIA ERNESTO 502720, and GARCIA ERNESTO VARGAS. "Dotar a la acción penal privada de un procedimiento que haga eficaz la impartición de justicia penal." Tesis de doctorado, Universidad Autónoma del Estado de México, 2016. http://hdl.handle.net/20.500.11799/58242.

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En el capítulo primero se desarrolló con apego al método histórico, el cual permitió conocer el trato que se le dio a la víctima u ofendido en el procedimiento penal, en el siglo V (procedimiento no jurisdiccional). La investigación utiliza el método analítico, con el cual se examina el papel de la víctima sancionando al infractor con la autorización de su comunidad, la cual legitimaba su actuar, debido a que la víctima era considerada parte central en el sistema de justicia penal, esta forma de impartir justicia es el antecedente de la acción penal privada, tema en estudio, por esta razón, se

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Ferrara, Giulia <1990&gt. "Doti, corredi e Spose nella Venezia del Cinquecento: Politiche matrimoniali, sistema dotale e aspetti materiali." Master's Degree Thesis, Università Ca' Foscari Venezia, 2016. http://hdl.handle.net/10579/8895.

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Questo studio ha l’obbiettivo di mettere in luce il ruolo che le patrizie veneziane rivestono all’interno della propria famiglia di origine durante il Cinquecento, studiando le strategie matrimoniali in rapporto ai complessi equilibri socio-economici e politici della Repubblica. Allo scopo di indagare il tema della dote ho preso in esame alcuni casi di studio, come i contratti matrimoniali delle figlie di Giacomo Ragazzoni (1528-1610), mercante rispettato dal patriziato e dalle imponenti risorse economiche, per meglio esprimere la problematica che riguarda le doti a Venezia durante il XVI seco

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Terp, Megan Cavanaugh. "Improved Nanoparticle Preparation and Delivery Technology for DOTAP and Oligonucleotide Based Lipoplexes." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1338301430.

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12

Graves, S., H. Valdovinos, W. Cai, T. Barnhart, and R. Nickles. "Pursuit of purity: Measurement of chelation binding affinities for NOTA, DOTA, and desferal with applications to effective specific activity." Helmholtz-Zentrum Dresden - Rossendorf, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:d120-qucosa-166419.

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Introduction The effective specific activity of a radioisotope is an indirect and highly useful way to describe a radioactive sample’s purity. A high effective specific activity combines the concept of an isotopically pure product with suitability via selectivity of a particular chelating body. The primary goals of this work are twofold: 1) To determine which metallic impurities have the largest impact on the effective specific activity for a given chelator, and 2) to form a model based on the binding affinities of each metal for to calculate a ‘theoretical effective specific activ-ity’ from b

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Schroer, Christine. "In vitro-Untersuchungen zum Einsatz von DOTAP in der Gentherapie der Cystischen Fibrose /." [S.l. : s.n.], 1999. http://www.gbv.de/dms/bs/toc/303409436.pdf.

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Clinton, Jonathan. "Using Membership Categorisation Analysis to Study Identity Creation in the Digital game Dota2." Thesis, Södertörns högskola, Institutionen för kultur och lärande, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-28704.

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One aspect of the internet that has been discussed in relation to identity creation is whether we can transcend our physical selves when we enter an online environment, thus potentially creating the internet as a space where we could leave our bodies when performing our identity. The purpose of this master thesis is to investigate the accomplishment of membership categorization within the domain of online gaming and through it identity in an online gaming environment. This thesis argues that the discourse within Dota2 constructs the identity of the unsuccessful gamer as an outsider or deviant

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Silva, Ana Claudia Machado. "Cinética e dosimetria do [177Lu-DOTA0, Tyr3]octreotato em pacientes com tumores carcinoides." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/85/85131/tde-29102014-130657/.

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Tumores carcinoides (neoplasias bem diferenciadas) são tumores neuroendócrinos que podem surgir em diferentes locais anatômicos. Na população a prevalência dos tumores carcinoides é de aproximadamente 10 casos para um milhão de habitantes e sua incidência é maior na quinta e sexta década de vida. Este trabalho propõe um modelo cinético baseado na teoria da análise compartimental em humanos com tumores carcinoides que se submeterão ao tratamento com o radiofármaco [177Lu-DOTA0,Tyr3]Octreotato. Imagens cintilográficas dinâmicas planares, obtidas imediatamente à injeção de 370 MBq (10 mCi) do rad

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16

Ollier, Sylvie. "Régime dotal et pratiques communautaires d'après les notaires de Draguignan (1655 à 1715)." Nice, 1997. http://www.theses.fr/1997NICE0041.

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Le droit matrimonial provençal sera dominé pendant tout l'ancien régime par des règles de droit romain. Le régime dotal sera ainsi appliqué avec une certaine rigueur dans toute la Provence et plus particulièrement dans le var. Toutefois, les contrats de mariages contenus dans les registres notariés de Draguignan entre 1655 et 1715, tendraient a démontrer un certain affaiblissement du caractère séparatiste du régime dotal. Les époux étant avant tout soucieux d'assurer les droits du conjoint survivant dans une Provence en crise. De plus, le régime dotal est le plus souvent absorbe dans une commu

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Johansson, Filip, and Jesper Wikström. "Result Prediction by Mining Replays in Dota 2." Thesis, Blekinge Tekniska Högskola, Institutionen för datalogi och datorsystemteknik, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-2288.

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Context: Real-time games like Dota 2 lack the extensive mathematical modeling of turn-based games that can be used to make objective statements about how to best play them. Understanding a real-time computer game through the same kind of modeling as a turn-based game is practically impossible. Objectives: In this thesis an attempt was made to create a model using machine learning that can predict the winning team of a Dota 2 game given partial data collected as the game progressed. A couple of different classifiers were tested, out of these Random Forest was chosen to be studied more in depth.

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Pessoa, Victor Felipe Barbosa. "Videogames e comunicação: dinâmicas de comunicação no Dota 2." Universidade Federal de Goiás, 2016. http://repositorio.bc.ufg.br/tede/handle/tede/6218.

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Submitted by Luciana Ferreira (lucgeral@gmail.com) on 2016-09-16T11:24:00Z No. of bitstreams: 2 Dissertação - Victor Felipe Barbosa Pessoa - 2016.pdf: 4794886 bytes, checksum: d1dc624e04b07c27cd9d7bf53df90955 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2016-09-16T11:24:33Z (GMT) No. of bitstreams: 2 Dissertação - Victor Felipe Barbosa Pessoa - 2016.pdf: 4794886 bytes, checksum: d1dc624e04b07c27cd9d7bf53df90955 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD

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Lindqvist, Kalle, and Dennis Nilsson. "Developing a 5v5 Framework for DotA 2 Bot Competition." Thesis, Malmö universitet, Fakulteten för teknik och samhälle (TS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-20773.

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Multiplayer online battle arena (MOBA) games have properties that make them suitable for research in artificial and computational intelligence. MOBA games are generally played team vs team meaning planning and organizing the team is one of the most important aspects. This makes it suitable for research in artificial intelligence agent cooperation. This paper presents a literature review performed in the area of artificial and computational intelligence regarding MOBA games. The findings are that there is little or no research made in the area. The research found concerning MOBA games is in the

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Brennecke, Benjamin Jakob [Verfasser]. "Enzyme-Responsive DOTA-Based Optical Probes / Benjamin Jakob Brennecke." Berlin : Freie Universität Berlin, 2021. http://d-nb.info/1237685869/34.

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21

SUPERBI, Silvia. "In dotem pro dote et dotis nomine. Il sistema dotale tra norma e prassi nella Ferrara del XIV secolo." Doctoral thesis, Università degli studi di Ferrara, 2012. http://hdl.handle.net/11392/2389435.

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In dotem pro dote et dotis nomine is the notarial form used in the dowry pacts during the Fourteenth century in Ferrara. The dowry system, which is the whole set of rules, legal practices, customs and rituals, is an interdisciplinary subject: focused on the economic and legal impact, the topic has also important social and cultural implications and it is connected with the artistic and literary production. The dowry is also considered by gender history as a key that allows an interpretation of the roles of men and women in relation to family and heritage. Through legislative and documentary so

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Andersson, Martin. "Phase Phenomena in Polymer Networks : Empirical Studies on the Influence of Hydrophobicity, Charge Density and Crosslinks on Macroion-Induced Phase Transitions in Polyelectrolyte Gels." Doctoral thesis, Uppsala universitet, Institutionen för farmaci, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-145381.

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The thesis concerns polyelectrolyte gels in contact with oppositely charged proteins and surfactant micelles, and includes of four papers (I-IV). In paper I confocal Raman spectroscopy was introduced as a method to trace micelles and investigate the structure of gel-surfactant complexes, in phase separated gel spheres. In paper II, the binding of surfactants to microspheres (~50-100 µm) was investigated by means of a micromanipulator-assisted microscopy method. The two surfactants were found to display qualitative difference respect to degree of swelling, surfactant distribution in the gels, a

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23

Audras, Matthieu. "Caractérisation structurale de complexes d'actinides (III) et (IV) par le ligand DOTA." Thesis, Montpellier 2, 2014. http://www.theses.fr/2014MON20096/document.

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Les anions polyaminocarboxylates ont été identifiés comme des composés d'intérêt pour les opérations de séparation des actinides, dans la migration des actinides dans l'environnement et dans la radiotoxicologie humaine. La caractérisation structurale de complexes formés entre les actinides et les ligands polyaminocarboxylates est essentielle pour une meilleure compréhension des interactions actinides – ligands. Parmi les anions polyaminocarboxylates, le macrocycle DOTA (acide 1,4,7,10-tétraazacyclododécane-tétraacétique) est décrit comme un agent complexant très fort des lanthanides(III), mais

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Exler, Michal. "Lokalizace stanic v Internetu pomocí systému King." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2011. http://www.nusl.cz/ntk/nusl-218842.

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This thesis is focus on problematics of nodes localization in Internet. There are describe methods for prediction latency by using artificial coordinates systems and by using direct measurement. This thesis is primarily focus on method names King, which is estimates latency between arbitrary end hosts by using recursive DNS queries in system for translate domain name.

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Barboříková, Hana. "Směsné lipidy a jejich interakce s biopolymery." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2017. http://www.nusl.cz/ntk/nusl-316157.

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This thesis focuses on the study of interactions between hyaluronan and lipid DOTAP and its mixtures with DPPC in water. First, the aggregation behavior of the lipid itself and its mixtures was measured, afterwards the influence of hyaluronan in different concentration was studied. Further the fluorescence anisotropy of fluorescence probe DPH in these mixtures and influence of cholesterol was measured. These properties were investigated by fluorescence spectoscopy using pyrene and DPH as fluorescence probes. The measurements revealed that the addition of hyaluronan has observable influence on

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Hanna, Jill. "Applications of DOTA-Lanthanide "Click" complexes to sensing and imaging." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/8743.

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While copper is an essential micronutrient in all living organisms, copper misregulation in humans is associated with neurodegenerative disorders such as Menkes and Wilson’s diseases, amyotrophic lateral sclerosis and Alzheimer’s disease. Furthermore, copper is a widely-produced pollutant and thus the detection of Cu(II) and Cu(I) has received much attention in recent years. Copper can be detected in a number of ways including; quenching of fluorescence upon the binding of paramagnetic Cu(II) (a "turn-off" response); augmentation of fluorescence upon Cu(II) binding due to PET modulation (a "tu

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Kriemen, Ella [Verfasser]. "Synthese modularer DOTA-Derivate für die zielgerichtete Tumordiagnostik / Ella Kriemen." München : Verlag Dr. Hut, 2015. http://d-nb.info/1079768211/34.

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Illy, Marie-Claire. "Etude du comportement paramagnétique des actinides en solution avec des ligands polyaminocarboxylates cycliques." Thesis, Montpellier, 2018. http://www.theses.fr/2018MONTS140/document.

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« Etude du comportement paramagnétique des actinides en solution avec des ligands polyaminocarboxylates cycliques »Le comportement paramagnétique des cations actinide (éléments 5f) peut être étudié via la spectroscopie RMN liquide en suivant deux axes de recherche complémentaires : les susceptibilités magnétiques et les déplacements chimiques.Dans un premier temps, lorsque les interactions entre le cation actinide et le ligand sont négligeables, la susceptibilité magnétique molaire est accessible par la méthode d’Evans. Cette méthode est applicable pour des échantillons en solution autour de l

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Pinède, Laurent. "Le traitement de la maladie thromboembolique veineuse des membres inférieurs : durée optimale de prescription des anticoagulants oraux : essai contrôlé multicentrique DOTAVK." Lyon 1, 2000. http://www.theses.fr/2000LYO1T010.

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Kerdjoudj, Rabha. "Scandium complexes : physico-chemical study and evaluation of stability in vitro and in vivo for nuclear medicine application." Thesis, Nantes, Ecole des Mines, 2014. http://www.theses.fr/2014EMNA0191/document.

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Parmi les différents isotopes du Scandium qui peuvent être utilisés en médecine nucléaire, on peut citer le ⁴⁷Sc et le ⁴⁴Sc. Le premier se désintègre en émettant un électron associé à un gamma de 159 keV et peut donc être utilisé soit pour faire de la radiothérapie, soit de l’imagerie TEMP. Le ⁴⁴Sc (3.97 h) se désintègre dans 94.27 % des cas en émettant un positron, accompagné d’un photon γ d’énergie égale à 1.157 MeV. Cet isotope est alors un candidat idéal pour des applications en imagerie TEP. Actuellement, le Cyclotron de haute énergie et haute intensité Arronax produit le ⁴⁴Sc et coprodui

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Fiegel, Vincent. "Radiolyse alpha des acides polyaminocarboxyliques en solution aqueuse : cas du ligand DOTA." Thesis, Montpellier, 2020. http://www.theses.fr/2020MONTS024.

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La stabilité radiolytique du ligand DOTA (acide 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetique), choisi comme ligand modèle de la famille des acides polyaminocarboxyliques, a été étudié par irradiation externe au moyen de faisceau d’hélions ou par rayonnement gamma ainsi que par irradiation interne par introduction de radioéléments directement dans la solution. Les rendements radiolytiques de formation de certaines espèces dans le milieu (H2, CO2, H2O2, HNO2…) ont été déterminés et les produits de dégradation du ligand ont été identifiés en faisant varier la concentration de ligand DOTA

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Bush, John Peyton. "The Stimulation of Dendritic Cells by Cationic Lipids." UKnowledge, 2019. https://uknowledge.uky.edu/medsci_etds/10.

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The discovery that cationic lipids can independently stimulate the immune system has generated interest in their potential as vaccine adjuvants. Here, we show that the cationic lipid R-DOTAP can independently stimulate type 1 interferon production in dendritic cells in both primary culture and immortalized cell culture. Levels of type 1 interferon production are cell line-dependent and limited in vitro by lipid-induced cell death. We show that cationic lipids can independently activate TLR-7 and TLR-9, suggesting a mechanism for type 1 interferon induction. This TLR-stimulatory activity is not

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Akanji, Akinkunmi Ganiyu. "Estudo de conjugação do anticorpo anti-CD20 para marcação com radionuclídeos metálicos ou lantanídeos." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/85/85131/tde-06092017-084114/.

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Linfomas são cânceres que se iniciam a partir da transformação maligna de um linfócito no sistema linfático. Os linfomas são divididos em duas categorias principais: os linfomas de Hodgkin e todos os outros linfomas, denominados linfomas não-Hodgkin (LNH). Os pacientes com LNH são comumente tratados com radioterapia apenas ou combinada com quimioterapia utilizando-se de anticorpo monoclonal anti-CD20, principalmente o rituximab (MabThera&reg). O uso de anticorpos monoclonais (Acm) conjugados à quelantes bifuncionais radiomarcados com radionuclídeos metálicos ou lantanídeos é uma realidade de t

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Andersson, John, and Oskar Alin. "Analyzing Factors Contributing to the Success of a Team in Dota 2." Thesis, KTH, Skolan för teknikvetenskap (SCI), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-230202.

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Competitive gaming or E-Sport is more popular than ever, this has resulted inan increase in the number of players and tournament prize pools. In traditionalsports demographic factors have been shown to have high predictive power whenit comes to determining a country's success in the Olympic Games. Similarresults have been found when it comes to E-sport which is why it is interestingto investigate whether there are any dierences between regions in Dota 2 aswell. The goal is to analyze factors that contribute to the success of a Dota 2team by building a multiple-regression model. All data is col

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Viro, Sebastian. "Using statistics and game knowledge to create better bots in Dota 2." Thesis, Malmö universitet, Fakulteten för teknik och samhälle (TS), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-43442.

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Multiplayer online battle arena (MOBA) games and games in general offer developers opportunities to design and test AI to further push research within the area. MOBA is a genre that has seen an increase in popularity during recent years alongside a rapidly growing esports scene. The game's main purpose is ultimately to be enjoyed and played by human players, who often come up with and are encouraged to create their own strategies in order to beat the game or win out over their opponents. This thesis will explore how mimicking human behavior in AI and using statistics from human players can b

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Kannengießer, Stefanie [Verfasser], and Thomas [Akademischer Betreuer] Fanghänel. "Optimization of the Synthesis of Ac-225-labelled DOTA-Radioimmunoconjugates for Targeted Alpha Therapy, based on Investigations on the Complexation of Trivalent Actinides by DOTA / Stefanie Kannengießer ; Betreuer: Thomas Fanghänel." Heidelberg : Universitätsbibliothek Heidelberg, 2013. http://d-nb.info/1177148838/34.

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Paakkonen, Johan. "Surfactants in anionic latex films." Thesis, Karlstads Universitet, Avdelningen för kemi och biomedicinsk vetenskap, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-6389.

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Widin, Viktor, and Julien Adler. "On using Artificial Neural Network models to predict game outcomes in Dota 2." Thesis, KTH, Skolan för datavetenskap och kommunikation (CSC), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-209270.

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Dota 2 is an online strategy game, played in a five versus five format. Its multitude of selectable characters, each with a unique set of abilities and spells, causes every new match to be different from the last and picking the right characters can ultimately decide whether a team wins or loses a game. This report investigates if Artificial Neural Networks can be used to predict game outcomes, based solely on the character selection made in each game. Additionally, the report will explore if altering the base parameters of the utilized ANN models can improve predictive performance. The models

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Domingo, Rommel J. "Pre-targeted radioimmunotherapy with streptavidin-CC49 monoclonal antibody and §9§0Y-DOTA-biotin." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ29337.pdf.

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Ilya, Musabirov. "Deconstructing Fame : An Analysis of eSports Brand Value. The Case of Dota 2." Thesis, Uppsala universitet, Medier och kommunikation, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-296411.

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ALDEGHERI, ELIANE B. "Avaliacao in vivo e in vitro do dota-lanreotideo radiomarcado com galio-67." reponame:Repositório Institucional do IPEN, 2005. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11372.

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Made available in DSpace on 2014-10-09T12:51:13Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:09:36Z (GMT). No. of bitstreams: 1 11255.pdf: 3481749 bytes, checksum: 00aea80e8fd8e4ad3fbe875c87600b5c (MD5)<br>Tese (Doutoramento)<br>IPEN/T<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP

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Poret, Benjamin. "Développement d'analogues urotensinergiques radiomarqués pour l'imagerie de tumeurs solides." Thesis, Normandie, 2018. http://www.theses.fr/2018NORMR028/document.

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La surexpression de récepteurs couplés aux protéines G (RCPG) dans certains cancers est mise à profit en médecine nucléaire pour développer des radioligands capables de diagnostiquer la présence de tumeurs. A titre d’exemple, des analogues de la somatostatine marqués à l’indium-111 (111In-OctreoScan) sont utilisés pour le diagnostic de tumeurs neuroendocrines. L’urotensine II (UII), qui présente des homologies structurales avec la somatostatine, est considérée comme le neuropeptide vasoactif le plus puissant découvert à ce jour. L’UII interagit avec un unique RCPG de très haute affinité appelé

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Hajjaj, Bouchra. "Conception, synthèse et évaluation biologique d’antagonistes de la bombésine pour la visualisation de cancers par imagerie médicale." Thesis, Montpellier 1, 2013. http://www.theses.fr/2013MON13517.

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La surexpression des récepteurs GRP au niveau de différents types de cancers communs offre la possibilité d'utiliser des analogues radiomarqués de la bombésine pour leur diagnostic et leur traitement. Ce travail de thèse est consacré à la conception, la synthèse et l'évaluation biologique de nouveaux radiopharmaceutiques, contenant un antagoniste des récepteurs GRP, un bras espaceur et le chélatant cyclique DOTA. Nous avons tout d'abord déterminé la longueur du bras espaceur permettant une optimisation des propriétés biologiques. Puis en se basant sur les résultats de cette étude nous avons ré

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Garske-Román, Ulrike. "177Lu-DOTA-octreotate Radionuclide Therapy of Neuroendocrine Tumours : Dosimetry-Based Therapy Planning and Outcome." Doctoral thesis, Uppsala universitet, Institutionen för medicinska vetenskaper, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-183417.

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Peptide receptor radionuclide therapy for the internal radiation of neuroendocrine tumours expressing somatostatin receptors has made great advances and offers promising results. 177Lu-DOTA-octreotate is one of the most widely used radiopeptides, but kidneys and bone marrow are organs at risk. Methods of measuring radiation doses to at-risk organs and tumours (dosimetry) on an individual patient basis have been regarded as impracticable and a maximum of 4 treatment cycles has widely been accepted as the treatment standard instead. The first aim of this thesis was to establish a clinically feas

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Uhlmann, Robin [Verfasser]. "Die Peptid-Radio-Rezeptor-Therapie neuroendokriner Tumoren mit Yttrium-90-DOTA-NOC / Robin Uhlmann." Ulm : Universität Ulm, 2017. http://d-nb.info/1137264802/34.

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Vanezi, Maria [Verfasser]. "Fernmetastasierte neuroendokrine Tumoren des Pankreas: Ansprechen auf Radiopeptidtherapie mit 177Lu-DOTA-Octreotat / Maria Vanezi." Bonn : Universitäts- und Landesbibliothek Bonn, 2020. http://d-nb.info/1218301716/34.

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Bulygin, Denis. "How do people evaluate virtual goods in social media? The case of Dota 2." Thesis, Uppsala universitet, Människa-datorinteraktion, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-389395.

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Virtual purchases are the main source of revenue for developers of F2P games being a market with expected 17.4 billions of dollars volume in 2019. Despite the broad scope of research of virtual purchases, it is still unclear how the player evaluate non-functional goods. Based on analysis of discussions of virtual decorative items this work what experiences nonfunctional items grants players with and how those experiences discussions reflect in the item’s price. With the use of Structural Topic Modeling framework this work demonstrates the dimensions of players’ experience in their association

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Webber, Benjamin Charles. "Investigation of the Structure and Dynamics of Regioisomeric Eu³⁺ and Gd³⁺ Chelates of NB-DOTMA: Implications for MRI Contrast Agent Design." PDXScholar, 2013. https://pdxscholar.library.pdx.edu/open_access_etds/1498.

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The detection of disease and abnormal pathology by magnetic resonance imaging (MRI) has been aided significantly by the use of gadolinium (Gd3+)-based contrast agents (CAs) over the past three decades. MRI and MRI CAs play a critical role in diagnosing tumors and diseases of the central nervous system. The agents used clinically have been shown to safely increase MRI contrast despite the toxicity of Gd3+, owing to the high kinetic and thermodynamic stability of these chelates. However, current CAs enhance contrast at a small fraction of what is theoretically possible. This leads to the necessi

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Ixcol, Mus Carmelita Faustina. "El significado de los llamados “linchamientos” en Guatemala y las prácticas que los dotan de sentido. Un estudio desde las comunidades mayas." Doctoral thesis, Universitat Autònoma de Barcelona, 2013. http://hdl.handle.net/10803/129091.

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La investigación trata del significado de los llamados “linchamientos” en Guatemala y analiza las prácticas que los dotan de sentido. Se trata de un estudio realizado desde las mismas comunidades mayas a fin de identificar construcciones de sentido asociadas a un entramado sociocultural que concibe e interpreta los llamados “linchamientos” desde un marco de inteligibilidad diferente al habitualmente establecido y que puede presumirse conectado con formas propias de resolución de conflictos. La pretensión de la tesis es romper con la comprensión de los llamados “linchamientos” como una mera e

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Álvarez, Acuña Carlos, and Acuña Carlos Álvarez. "“ANÁLISIS Y PERSPECTIVAS AL DOTAR DE AUTONOMÍA AL SISTEMA DE AGUAS DE LA CIUDAD DE MÉXICO EN MATERIA FINANCIERA Y DE GESTIÓN”." Tesis de Licenciatura, Facultad de Ciencias Políticas y Sociales, 2014. http://hdl.handle.net/20.500.11799/13694.

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La problemática del agua potable ha sido un tema crucial que debe ser atendido por las autoridades en conjunto con la sociedad, puesto que se ven afectados los intereses sociales, políticos y ambientales. El otorgarle autonomía plena al órgano encargado de administrar el sistema hidráulico de la Ciudad de México, permitirá un manejo eficaz de los recursos que le son encomendados. Aunado a ello, si se respalda la descentralización mediante la Gestión Integral de los Recursos Hídricos (GIRH) coadyuvará a la efectividad en su gestión técnica y financiera. En el Distrito Federal, el sistema de agu

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