Academic literature on the topic 'Downstream process'

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Journal articles on the topic "Downstream process"

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De Palma, Angelo. "Downstream Process Bottlenecks." Genetic Engineering & Biotechnology News 33, no. 13 (July 2013): 1, 36. http://dx.doi.org/10.1089/gen.33.13.17.

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Langer, Eric S. "Alleviating Downstream Process Bottlenecks." Genetic Engineering & Biotechnology News 31, no. 13 (July 2011): 1–49. http://dx.doi.org/10.1089/gen.31.13.18.

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Friedl, Anton. "Downstream process options for the ABE fermentation." FEMS Microbiology Letters 363, no. 9 (March 27, 2016): fnw073. http://dx.doi.org/10.1093/femsle/fnw073.

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Strube, Jochen, Florian Grote, Jan Pablo Josch, and Reinhard Ditz. "Process Development and Design of Downstream Processes." Chemie Ingenieur Technik 83, no. 7 (June 9, 2011): 1044–65. http://dx.doi.org/10.1002/cite.201100017.

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Yee, C. L., K. H. Tan, and K. W. Platts. "Managing ‘downstream’ supply network: A process and tool." International Journal of Production Economics 104, no. 2 (December 2006): 722–35. http://dx.doi.org/10.1016/j.ijpe.2004.10.008.

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Hämäläinen, Jari J., Ilpo Järvimäki, Robert Weiss, Jan Dahl, and Stefan Ekbom. "Predictive Planning and Control of a Downstream Process." IFAC Proceedings Volumes 33, no. 10 (June 2000): 575–80. http://dx.doi.org/10.1016/s1474-6670(17)38602-0.

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Darnon, E., E. Morin, M. P. Belleville, and G. M. Rios. "Ultrafiltration within downstream processing: some process design considerations." Chemical Engineering and Processing: Process Intensification 42, no. 4 (April 2003): 299–309. http://dx.doi.org/10.1016/s0255-2701(02)00053-3.

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AKIYAMA, Juichiro, Le Dinh HONG, and Masaru Meura. "ANALYSIS OF SCOUR PROCESS DOWNSTREAM OF A SLUICE." PROCEEDINGS OF HYDRAULIC ENGINEERING 35 (1991): 489–94. http://dx.doi.org/10.2208/prohe.35.489.

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Magalhães, Antonio Irineudo, Júlio Cesar de Carvalho, Jesus David Coral Medina, and Carlos Ricardo Soccol. "Downstream process development in biotechnological itaconic acid manufacturing." Applied Microbiology and Biotechnology 101, no. 1 (November 15, 2016): 1–12. http://dx.doi.org/10.1007/s00253-016-7972-z.

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Martínez, Ernesto Acosta, João Batista de Almeida e Silva, Marco Giulietti, and Ana Irene Nápoles Solenzal. "Downstream process for xylitol produced from fermented hydrolysate." Enzyme and Microbial Technology 40, no. 5 (April 2007): 1193–98. http://dx.doi.org/10.1016/j.enzmictec.2006.09.003.

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Dissertations / Theses on the topic "Downstream process"

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Weber, Andreas [Verfasser]. "Process Analysis of Biosurfactant Downstream Processing / Andreas Weber." München : Verlag Dr. Hut, 2014. http://d-nb.info/1063222281/34.

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Bibi, Noor Shad [Verfasser]. "Downstream process intensification by innovative material development / Noor Shad Bibi." Bremen : IRC-Library, Information Resource Center der Jacobs University Bremen, 2012. http://d-nb.info/1035266261/34.

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Winkelnkemper, Torsten [Verfasser]. "Key performance indicators for economic downstream process development / Torsten Winkelnkemper." München : Verlag Dr. Hut, 2012. http://d-nb.info/102424279X/34.

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Hahn, Tobias [Verfasser], and J. [Akademischer Betreuer] Hubbuch. "Advances in Model-based Downstream Process Development / Tobias Hahn. Betreuer: J. Hubbuch." Karlsruhe : KIT-Bibliothek, 2015. http://d-nb.info/1081213078/34.

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Chibuye, Lweendo, and Eva Löfgren. "Performance Measurement Systems : pre-conditions & implementation process for manufacturers moving downstream." Thesis, KTH, Industriell ekonomi och organisation (Inst.), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-124522.

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Manufacturers have in recent years become more and more aware of the benefits of offering more comprehensive value propositions. As the economic climate changes, more manufacturers are trying to capture value further downstream in the value chain by providing services. The field of performance management has been extensively adopted in production and the benefits of performance measurement have been widely praised both in literature and in business. The literature on performance management has also extended into service management and how to manage service performance. But how can performance measurement and performance measurement systems be implemented when the line between products and services becomes more and more unclear? Over a twenty week period, the researchers have studied, analyzed, and observed the procedures at Scania CV’s maintenance development and delivery organization. The study was conducted on Scania’s premises in Södertälje, Sweden. Scania’s Preventative Maintenance Development group develops and sets the requirements for the preventative maintenance programs Scania offers to its customers. The group had a desire to track and measure what effects changes made in the maintenance program have on the customer’s life cycle profit. At Scania’s Preventative Maintenance Development group, there is a developed performance measurement system, MPI-model, consisting of maintenance performance indicators (MPIs). The current MPI-model, however, lacks practical applicability. The master thesis has aimed at investigating how the MPI-model could be implemented in the preventative maintenance development by researching what criteria are set in literature for performance measures, how existing resources can be employed, and how performance measurement systems can be used. Apart from conducting a case study, in order to investigate how performance measurement systems could be implemented, an extensive literature review was also conducted to provide the necessary theoretical knowledge. The result of the study was a proposed three-step model that clarifies the requirements for the implementation of a performance measurement system.
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Zheng, Yizhou. "Process development for downstream processing of human growth hormone and its antagonist." Ohio : Ohio University, 1994. http://www.ohiolink.edu/etd/view.cgi?ohiou1174330360.

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Matthey-de-l'Endroit, François. "A new downstream process for a unique lipoteichoic acid established via quantitative immunoanalysis /." [S.l.] : [s.n.], 1999. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=13536.

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Liu, Jiahong. "Downstream process synthesis for biochemical production of butanol, ethanol, and acetone from grains /." Search for this dissertation online, 2003. http://wwwlib.umi.com/cr/ksu/main.

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Johansson, Emma. "Effect of filtration aid on downstream processing of polymer particles : Effektivisering av avvattningsprocessen av polymerpartiklar." Thesis, Luleå tekniska universitet, Industriell miljö- och processteknik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-74944.

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Polymer particles are expandable and produced by Nouryon. The production consists of polymerization, dewatering and drying. Dewatering of polymer particlesis an important part of the production process and have a large impact on how efficient the downstream process can be performed. An efficient dewatering enablesa fast and effective drying process and is therefore of great importance for a fastproduction process. Here, today, there are big variations. For mostpolymer particlegradesthe dewatering aid DEW1is added to the slurry. DEW1is a non-ionic surfactant that greatly increases dewatering abilities of slurry and thus increases speedof the downstream process. But, DEW1cannotbeused for allpolymer particlegrades due to regulations. Therefore, thosepolymer particlesdemand longer downstream times with higher production costs and higher energy consumption following. The aim ofthisdiploma work was to find an alternative dewatering aid which can be used for all polymer particle grades, has a good environmental profile and increases speed of the drying process. Several compounds weretestedin laboratory scaleduring this studyto investigatetheir effect ondry contentafter dewatering.One ofthem, DEW2, showedpromising features as an alternativedewatering aid which isalso bio-based. The highestdry content ofdewatered polymer particleslurrywith DEW2as dewatering aidwasXwt% dry polymer particles.This was2.2wt% higher dry content thanthe results achieved with DEW1.Also, the effect of heated polymer particleslurry and wash water on dry content wasinvestigatedduring this study. A strong relation between higher temperatures of especially wash water and increased dry content of dewatered polymer particleswasdetected. The highest dry content achieved was Xwt% dry polymer particlesfrom a test with slurry 20 °Cand wash water 80 °C. This was an increase in dry content with 26.9 % compared to the lowest dry content achieved. The lowest value was obtained when both slurry and wash water temperature was 20 °C, which during these tests gave a dry content of Xwt%. However, polymer particlesfrom testswith high temperatures showed signs of agglomerationof polymer particles on dispersion testwhich is not accepted for polymer particles of good quality.Two full scale production trialswere performed with wash water heated to 40 °C. No agglomerated polymer particleswereseen in the dried product, and the production speed increased with 18 respectively 11 %
Polymerpartiklar är expanderbara och producerade av Nouryon. Produktionen består av polymerisation, avvattning samt torkning.Avvattning avpolymerpartikelslurry är en stordel av efterbehandlingsprocessenoch det är viktigt att den kan genomföras effektivtför att minska tids-och energiåtgång. En väl fungerande avvattning främjar en snabb och effektiv torkprocess och är därför av stor betydelse för en snabb produktionsprocess. Idag finns stora variationergällande tidsåtgång beroende påvilken polymerpartikelskvalitet som produceras. Till de flesta polymerpartikelskvalitetertillsättsDEW1som fungerar somavvattningshjälpmedel. DEW1är en non-jonisk tensid som avsevärt förbättrar avvattningskapacitetenför polymerpartikelslurrynoch därmed förkortar efterbehandlingstidenoch därmed den totala produktionstiden. Dock kan inte DEW1användas föralla typer av polymerpartiklar.Det medför att produktionstidenförlängsför dessa kvaliteter, vilketleder till högre produktionskostnader samt en högre energiförbrukning. Syftet med det här examensarbetet varatt hitta ett alternativt avvattningshjälpmedelsom är miljövänligt,ökarhastigheten på avvattning-och torkningsprocessenoch som kan användas för alla typer av polymerpartiklar. Ett antal substansertestadesunder examensarbetet laborativt för att utvärdera deras effekt påtorrhalt på polymerpartiklarefter avvattning. Det biobaseradeavvattningshjälpmedlet DEW2såglovande ut med goda avvattningsegenskaper. Resultaten från försök med DEW2gav2.2wt% högre torrhaltän DEW1. Andra försök gjordes under examensarbetetför att undersöka sambandet mellan temperatur på polymerpartikelslurryoch tvättvatten mot torrhalt på avvattnade polymerpartiklar. Högre temperatur på speciellt tvättvatten gavhögre torrhalt, och den högsta torrhalten som uppnåddes vid försöken varXwt%med en slurrytemperatur på 20 °Coch tvättvattentemperatur på80 °C.Jämfört med det sämsta resultatet för torrhalt var det en ökningmed26.9%mot resultatet från tester utförda med slurry och tvättvattentemperatur 20 °C, som gav torrhalten Xwt%. Dessvärre visadedispersionstesterfrån testerutförda med temperaturer mellan 50 till 80 °Catt agglomerat bildatsi torkade polymerpartiklar.Två produktionstester utfördes där tvättvattnet värmdes till 40 °C. Här sågs inga problem med agglomerat i färdig produktoch produktionshastigheten ökade med 18 respektive 11 %.
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Thygs, Fabian B. [Verfasser]. "Automation Techniques to Support Experimental Investigation During Systematic Downstream Process Development / Fabian B. Thygs." München : Verlag Dr. Hut, 2017. http://d-nb.info/1149580240/34.

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Books on the topic "Downstream process"

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A, Brown Richard. Impact of anion exchange pre-treatment on downstream processes. Denver, CO: Water Research Foundation, 2011.

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Ausstellungstagung, für Chemisches Apparatewesen (22nd 1988 Frankfurt am Main Germany). Bioreactors, downstream processing, process and reactor modelling, bioprocesses: Lectures held at ACHEMA '88, June 5/11, 1988. Weinheim: VCH, 1988.

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Downstream Process Technology a New Horizon in Biotechnology. PHI Learning, 2010.

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(Editor), Dieter Behrens, and P. Kramer (Editor), eds. Bioreactors, Downstream Processing, Process and Reactor Modelling and Bioprocesses. Wiley-VCH, 1989.

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(Editor), D. Behrens, and Patricia Kramer (Editor), eds. Bioreactors, Downstream Processing, Process & Reactor Modelling, Bioprocesses (Dechema Biotechnology Conferences,). Wiley-VCH Verlag GmbH, 1989.

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Horn, Carsten Stefan. Downstream processing with affinity chromatography: A study of a continuous process for biospecific adsorption. 1993.

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(Contributor), K. H. Bellgardt, S. R. Gerlach (Contributor), R. King (Contributor), P. Krabben (Contributor), J. Nielsen (Contributor), G. C. Paul (Contributor), M. N. Pons (Contributor), et al., eds. Relation Between Morphology and Process Performances (Advances in Biochemical Engineering / Biotechnology). Springer, 1997.

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Natural Gas Processing from Midstream to Downstream. Wiley, 2019.

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Hall, Kenneth R., Mahmoud M. El-Halwagi, Nimir O. Elbashir, and Ioannis G. Economou. Natural Gas Processing from Midstream to Downstream. Wiley & Sons, Incorporated, John, 2018.

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Wood, Geoffrey. Employee Participation in Developing and Emerging Countries. Edited by Adrian Wilkinson, Paul J. Gollan, Mick Marchington, and David Lewin. Oxford University Press, 2010. http://dx.doi.org/10.1093/oxfordhb/9780199207268.003.0023.

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Work and employment relations vary not only according to individual strategic choices by managers, and actions and responses by employees, but also by the social and economic context. Development is a complex and multifaceted process of structural transformation, including economic and social changes. While a common distinction is often drawn between nations who have attained a degree of socio-economic development characterized by certain levels of income, productivity, investment, formal employment, technological deployment and a range of human capital indicators, the latter category is an extremely broad one in itself. It may encompass ‘emerging market’ nations such as Brazil and South Africa, and nations where economic activity centres around the production of unprocessed or semi-processed primary commodities, with only limited downstream industrial development. This article primarily focuses on this second category, although some attention is also devoted to the case of ‘emerging markets’.
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Book chapters on the topic "Downstream process"

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Kumara Behera, Basanta, and Ajit Varma. "Downstream Processing." In Microbial Biomass Process Technologies and Management, 109–214. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-53913-3_3.

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Litman, S. "The facility design process." In Handbook of Downstream Processing, 509–29. Dordrecht: Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-009-1563-3_18.

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Petrides, D. P., and E. S. Sapidou. "Optimization of protein recovery using computer-aided process design tools." In Handbook of Downstream Processing, 658–81. Dordrecht: Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-009-1563-3_24.

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Spitali, Mariangela. "DOWNSTREAM PROCESSING OF MONOCLONAL ANTIBODY FRAGMENTS." In Process Scale Purification of Antibodies, 537–58. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781119126942.ch25.

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Thygs, Fabian B., and Juliane Merz. "Downstream Process Synthesis for Microbial Steroids." In Microbial Steroids, 321–45. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7183-1_23.

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Wang, Henry Y. "Downstream Process Design and Bioproduct Quality Control." In Separations for Biotechnology 2, 585–91. Dordrecht: Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-009-0783-6_62.

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Kelley, Brian. "DOWNSTREAM PROCESSING OF MONOCLONAL ANTIBODIES: CURRENT PRACTICES AND FUTURE OPPORTUNITIES." In Process Scale Purification of Antibodies, 1–21. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781119126942.ch1.

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Singh, Nripen, and Srinivas Chollangi. "NEXT-GENERATION CLARIFICATION TECHNOLOGIES FOR THE DOWNSTREAM PROCESSING OF ANTIBODIES." In Process Scale Purification of Antibodies, 81–112. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781119126942.ch4.

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Allen, Lee. "THE EVOLUTION OF PLATFORM TECHNOLOGIES FOR THE DOWNSTREAM PROCESSING OF ANTIBODIES." In Process Scale Purification of Antibodies, 365–89. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781119126942.ch17.

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Shukla, Abhinav A., and Carnley L. Norman. "DOWNSTREAM PROCESSING OF Fc FUSION PROTEINS, BISPECIFIC ANTIBODIES, AND ANTIBODY-DRUG CONJUGATES." In Process Scale Purification of Antibodies, 559–94. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781119126942.ch26.

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Conference papers on the topic "Downstream process"

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Fu, Yali, Shawming Ma, Yi Wang, Linda Sui, Lu Chen, Vijay Vaniapura, Li Diao, Mingjie Jiao, and Hongwei Chen. "Inductive Coupled Downstream Plasma CD Trim Process Stability Study." In 2019 China Semiconductor Technology International Conference (CSTIC). IEEE, 2019. http://dx.doi.org/10.1109/cstic.2019.8755658.

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Dubot, Didier, and Marie Lavielle. "Characterization and sampling upstream and downstream of clean up process." In Inventaire radiologique, caractérisation et échantillonnage en amont et en aval des opérations de démantèlement. Les Ulis, France: EDP Sciences, 2012. http://dx.doi.org/10.1051/jtsfen/2012inv05.

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"Soft Silicon Etch Using Microwave Downstream Plasma For Removal Of Plasma Etch Induced Damage." In 2nd International Symposium on Plasma Process-Induced Damage. IEEE, 1997. http://dx.doi.org/10.1109/ppid.1997.596699.

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Fu, Yali, Shawming Ma, Yi Wang, Ken Wang, Mingjie Jiao, Nancy Zhang, Vijay Vaniapura, Hai-Au Phan-Vu, and Bob Elliston. "Study of downstream CF4 contained plasma process impact on chamber condition." In 2018 China Semiconductor Technology International Conference (CSTIC). IEEE, 2018. http://dx.doi.org/10.1109/cstic.2018.8369224.

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Rangelow, Ivo W. "High-resolution tri-level process by downstream-microwave rf-biased etching." In Santa Cl - DL tentative, edited by James A. Bondur and Terry R. Turner. SPIE, 1991. http://dx.doi.org/10.1117/12.48912.

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Szykman, Simon. "Improving the Design Process by Predicting Downstream Values of Design Attributes." In ASME 1996 Design Engineering Technical Conferences and Computers in Engineering Conference. American Society of Mechanical Engineers, 1996. http://dx.doi.org/10.1115/96-detc/dtm-1520.

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Abstract This paper presents a computational approach to developing design space models that are utilized to improve the design process by predicting values of downstream design attributes based on information available at early stages, such as preliminary design specifications. The predictive models are similar in function, though not in form, to the internal (mental) models created by experienced designers; however, the advantages of these models are that it may be possible to construct them in the absence of a designer’s internal models, and that they can be passed on to and used by less experienced designers. Once created, the computational models aid designers in exploration of design alternatives and to reduce design costs and product development time.
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Bhatnagar, Vivek, Andrew Lloyd Smith, and Scott Berger. "Managing Process Safety Of The Upstream Sector: Lessons Learnt From The Downstream Industry." In SPE Offshore Europe Oil and Gas Conference and Exhibition. Society of Petroleum Engineers, 2011. http://dx.doi.org/10.2118/146321-ms.

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Yu, Wang, Miao Yunhui, Zhu Huabo, and Tang Jiafu. "A particle swarm optimization algorithm on the surgery scheduling problem with downstream process." In 2013 25th Chinese Control and Decision Conference (CCDC). IEEE, 2013. http://dx.doi.org/10.1109/ccdc.2013.6561041.

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Silayi, Gulibaha, Tsutomu Kinoshita, Katsutsugu Matsuyama, and Kouichi Konno. "Generating a Reference Model of the Surface with a Hole for Downstream Process." In CAD'15. CAD Solutions LLC, 2015. http://dx.doi.org/10.14733/cadconfp.2015.264-269.

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"Generating a Reference Model of the Surface with a Hole for Downstream Process." In CAD'15 London. CAD Solutions LLC, 2015. http://dx.doi.org/10.14733/cadconfp.2015.303-308.

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Reports on the topic "Downstream process"

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Haldipur, G., D. Schmidt, and K. Smith. A 50-month gasifier mechanistic study and downstream unit process development program for the pressurized ash-agglomerating fluidized-bed gasification system. Office of Scientific and Technical Information (OSTI), March 1989. http://dx.doi.org/10.2172/5395230.

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Haldipur, G., D. Schmidt, and K. Smith. A 50-month gasifier mechanistic study and downstream unit process development program for the pressurized ash-agglomerating fluidized-bed gasification system. Office of Scientific and Technical Information (OSTI), March 1989. http://dx.doi.org/10.2172/5395225.

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Davis, Ryan, Jennifer Markham, Christopher Kinchin, Nicholas Grundl, Eric C. D. Tan, and David Humbird. Process Design and Economics for the Production of Algal Biomass: Algal Biomass Production in Open Pond Systems and Processing Through Dewatering for Downstream Conversion. Office of Scientific and Technical Information (OSTI), February 2016. http://dx.doi.org/10.2172/1239893.

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Trainer, Asa, Allison Barnard Feeney, and Thomas D. Hedberg. Validation for Downstream Computer Aided Manufacturing and Coordinate Metrology Processes. National Institute of Standards and Technology, August 2016. http://dx.doi.org/10.6028/nist.gcr.16-003.

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Monarch, Ira A., Dennis R. Goldenson, and Lawrence T. Osiecki. Requirements and Their Impact Downstream: Improving Casual Analysis Processes Through Measurement and Analysis of Textual Information. Fort Belvoir, VA: Defense Technical Information Center, September 2008. http://dx.doi.org/10.21236/ada488178.

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Chen, Junping, Zach Adam, and Arie Admon. The Role of FtsH11 Protease in Chloroplast Biogenesis and Maintenance at Elevated Temperatures in Model and Crop Plants. United States Department of Agriculture, May 2013. http://dx.doi.org/10.32747/2013.7699845.bard.

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specific objectives of this proposal were to: 1) determine the location, topology, and oligomerization of FtsH11 protease; 2) identify the substrate/s of FtsH11 and the downstream components involved in maintaining thermostability of chloroplasts; 3) identify new elements involved in FtsH11 protease regulatory network related to HT adaptation processes in chloroplast; 4) Study the role of FtsH11 homologs from crop species in HT tolerance. Background to the topic: HT-tolerant varieties that maintain high photosynthetic efficiency at HT, and cope better with daily and seasonal temperature fluctuations are in great need to alleviate the effect of global warming on food production. Photosynthesis is a very complex process requiring accurate coordination of many complex systems and constant adjustments to the changing environments. Proteolytic activities mediated by various proteases in chloroplast are essential part of this process and critical for maintaining normal chloroplast functions under HT. However, little is known about mechanisms that contribute to adaptation of photosynthetic processes to HT. Our study has shown that a chloroplast-targeted Arabidopsis FtsH11 protease plays an essential and specific role in maintaining thermostability of thylakoids and normal photosynthesis at moderate HT. We hypothesized that FtsH11 homologs recently identified in other plant species might have roles similarly to that of AtFtsH1. Thus, dissecting the underlying mechanisms of FtsH11 in the adaptation mechanisms in chloroplasts to HT stress and other elements involved will aid our effort to produce more agricultural products in less favorable environments. Major conclusions, solutions, achievements - Identified the chloroplast inner envelope membrane localization of FtsH11. - Revealed a specific association of FtsH11 with the a and b subunits of CPN60. - Identified the involvement of ARC6, a protein coordinates chloroplast division machineries in plants, in FtsH11 mediated HT adaptation process in chloroplast. -Reveal possible association of a polyribonucleotide nucleotidyltransferase (cpPNPase), coded by At3G03710, with FtsH11 mediated HT adaptation process in chloroplast. - Mapped 4 additional loci in FtsH11 mediated HT adaptation network in chloroplast. - Demonstrated importance of the proteolytic activity of FtsH11 for thermotolerance, in addition to the ATPase activity. - Demonstrated a conserved role of plant FtsH11 proteases in chloroplast biogenesis and in maintaining structural and functional thermostability of chloroplast at elevated temperatures. Implications, both scientific and agricultural:Three different components interacting with FtsH11 were identified during the course of this study. At present, it is not known whether these proteins are directly involved in FtsH11mediated thermotolerance network in chloroplast and/or how these elements are interrelated. Studies aiming to connect the dot among biological functions of these networks are underway in both labs. Nevertheless, in bacteria where it was first studied, FtsH functions in heat shock response by regulating transcription level of σ32, a heat chock factor regulates HSPsexpression. FtsH also involves in control of biosynthesis of membrane components and quality control of membrane proteins etc. In plants, both Arc 6 and CPN60 identified in this study are essential in chloroplast division and developments as mutation of either one impairs chloroplast division in Arabidopsis. The facts that we have found the specific association of both α and β CPN60 with FtsH11 protein biochemically, the suppression/ enhancement of ftsh11 thermosensitive phenotype by arc6 /pnp allele genetically, implicate inter-connection of these networks via FtsH11 mediated network(s) in regulating the dynamic adaptation processes of chloroplast to temperature increases at transcriptional, translational and post-translational levels. The conserved role of FtsH11 proteases in maintaining thermostability of chloroplast at HT demonstrated here provides a foundation for improving crop photosynthetic performance at high temperatures.
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7

Premuzic, E. T. Economic feasibility of biochemical processes for the upgrading of crudes and the removal of sulfur, nitrogen, and trace metals from crude oil -- Benchmark cost establishment of biochemical processes on the basis of conventional downstream technologies. Final report FY95. Office of Scientific and Technical Information (OSTI), August 1996. http://dx.doi.org/10.2172/481474.

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8

Hutchinson, M. L., J. E. L. Corry, and R. H. Madden. A review of the impact of food processing on antimicrobial-resistant bacteria in secondary processed meats and meat products. Food Standards Agency, October 2020. http://dx.doi.org/10.46756/sci.fsa.bxn990.

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For meat and meat products, secondary processes are those that relate to the downstream of the primary chilling of carcasses. Secondary processes include maturation chilling, deboning, portioning, mincing and other operations such as thermal processing (cooking) that create fresh meat, meat preparations and ready-to-eat meat products. This review systematically identified and summarised information relating to antimicrobial resistance (AMR) during the manufacture of secondary processed meatand meat products (SPMMP). Systematic searching of eight literature databases was undertaken and the resultantpapers were appraised for relevance to AMR and SPMMP. Consideration was made that the appraisal scores, undertaken by different reviewers, were consistent. Appraisal reduced the 11,000 initially identified documents to 74, which indicated that literature relating to AMR and SPMMP was not plentiful. A wide range of laboratory methods and breakpoint values (i.e. the concentration of antimicrobial used to assess sensitivity, tolerance or resistance) were used for the isolation of AMR bacteria.The identified papers provided evidence that AMR bacteria could be routinely isolated from SPMMP. There was no evidence that either confirmed or refuted that genetic materials capable of increasing AMR in non-AMR bacteria were present unprotected (i.e. outside of a cell or a capsid) in SPMMP. Statistical analyses were not straightforward because different authors used different laboratory methodologies.However, analyses using antibiotic organised into broadly-related groups indicated that Enterobacteriaceaeresistant to third generation cephalosporins might be an area of upcoming concern in SPMMP. The effective treatment of patients infected with Enterobacteriaceaeresistant to cephalosporins are a known clinical issue. No AMR associations with geography were observed and most of the publications identified tended to be from Europe and the far east.AMR Listeria monocytogenes and lactic acid bacteria could be tolerant to cleaning and disinfection in secondary processing environments. The basis of the tolerance could be genetic (e.g. efflux pumps) or environmental (e.g. biofilm growth). Persistent, plant resident, AMR L. monocytogenes were shown by one study to be the source of final product contamination. 4 AMR genes can be present in bacterial cultures used for the manufacture of fermented SPMMP. Furthermore, there was broad evidence that AMR loci could be transferred during meat fermentation, with refrigeration temperatures curtailing transfer rates. Given the potential for AMR transfer, it may be prudent to advise food business operators (FBOs) to use fermentation starter cultures that are AMR-free or not contained within easily mobilisable genetic elements. Thermal processing was seen to be the only secondary processing stage that served as a critical control point for numbers of AMR bacteria. There were significant linkages between some AMR genes in Salmonella. Quaternary ammonium compound (QAC) resistance genes were associated with copper, tetracycline and sulphonamide resistance by virtue of co-location on the same plasmid. No evidence was found that either supported or refuted that there was any association between AMR genes and genes that encoded an altered stress response or enhanced the survival of AMR bacteria exposed to harmful environmental conditions.
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9

Aharoni, Asaph, Zhangjun Fei, Efraim Lewinsohn, Arthur Schaffer, and Yaakov Tadmor. System Approach to Understanding the Metabolic Diversity in Melon. United States Department of Agriculture, July 2013. http://dx.doi.org/10.32747/2013.7593400.bard.

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Fruit quality is determined by numerous genetic factors that affect taste, aroma, ‎color, texture, nutritional value and shelf life. To unravel the genetic components ‎involved in the metabolic pathways behind these traits, the major goal of the project was to identify novel genes that are involved in, or that regulate, these pathways using correlation analysis between genotype, metabolite and gene expression data. The original and specific research objectives were: (1) Collection of replicated fruit from a population of 96 RI lines derived from parents distinguished by great diversity in fruit development and quality phenotypes, (2) Phenotypic and metabolic profiling of mature fruit from all 96 RI lines and their parents, (3) 454 pyrosequencing of cDNA representing mRNA of mature fruit from each line to facilitate gene expression analysis based on relative EST abundance, (4) Development of a database modeled after an existing database developed for tomato introgression lines (ILs) to facilitate online data analysis by members of this project and by researchers around the world. The main functions of the database will be to store and present metabolite and gene expression data so that correlations can be drawn between variation in target traits or metabolites across the RI population members and variation in gene expression to identify candidate genes which may impact phenotypic and chemical traits of interest, (5) Selection of RI lines for segregation and/or hybridization (crosses) analysis to ascertain whether or not genes associated with traits through gene expression/metabolite correlation analysis are indeed contributors to said traits. The overall research strategy was to utilize an available recombinant inbred population of melon (Cucumis melo L.) derived from phenotypically diverse parents and for which over 800 molecular markers have been mapped for the association of metabolic trait and gene expression QTLs. Transcriptomic data were obtained by high throughput sequencing using the Illumina platform instead of the originally planned 454 platform. The change was due to the fast advancement and proven advantages of the Illumina platform, as explained in the first annual scientific report. Metabolic data were collected using both targeted (sugars, organic acids, carotenoids) and non-targeted metabolomics analysis methodologies. Genes whose expression patterns were associated with variation of particular metabolites or fruit quality traits represent candidates for the molecular mechanisms that underlie them. Candidate genes that may encode enzymes catalyzingbiosynthetic steps in the production of volatile compounds of interest, downstream catabolic processes of aromatic amino acids and regulatory genes were selected and are in the process of functional analyses. Several of these are genes represent unanticipated effectors of compound accumulation that could not be identified using traditional approaches. According to the original plan, the Cucurbit Genomics Network (http://www.icugi.org/), developed through an earlier BARD project (IS-3333-02), was expanded to serve as a public portal for the extensive metabolomics and transcriptomic data resulting from the current project. Importantly, this database was also expanded to include genomic and metabolomic resources of all the cucurbit crops, including genomes of cucumber and watermelon, EST collections, genetic maps, metabolite data and additional information. In addition, the database provides tools enabling researchers to identify genes, the expression patterns of which correlate with traits of interest. The project has significantly expanded the existing EST resource for melon and provides new molecular tools for marker-assisted selection. This information will be opened to the public by the end of 2013, upon the first publication describing the transcriptomic and metabolomics resources developed through the project. In addition, well-characterized RI lines are available to enable targeted breeding for genes of interest. Segregation of the RI lines for specific metabolites of interest has been shown, demonstrating the utility in these lines and our new molecular and metabolic data as a basis for selection targeting specific flavor, quality, nutritional and/or defensive compounds. To summarize, all the specific goals of the project have been achieved and in many cases exceeded. Large scale trascriptomic and metabolomic resources have been developed for melon and will soon become available to the community. The usefulness of these has been validated. A number of novel genes involved in fruit ripening have been selected and are currently being functionally analyzed. We thus fully addressed our obligations to the project. In our view, however, the potential value of the project outcomes as ultimately manifested may be far greater than originally anticipated. The resources developed and expanded under this project, and the tools created for using them will enable us, and others, to continue to employ resulting data and discoveries in future studies with benefits both in basic and applied agricultural - scientific research.
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10

Desiderati, Christopher. Carli Creek Regional Water Quality Project: Assessing Water Quality Improvement at an Urban Stormwater Constructed Wetland. Portland State University, 2022. http://dx.doi.org/10.15760/mem.78.

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Stormwater management is an ongoing challenge in the United States and the world at-large. As state and municipal agencies grapple with conflicting interests like encouraging land development, complying with permits to control stormwater discharges, “urban stream syndrome” effects, and charges to steward natural resources for the long-term, some agencies may turn to constructed wetlands (CWs) as aesthetically pleasing and functional natural analogs for attenuating pollution delivered by stormwater runoff to rivers and streams. Constructed wetlands retain pollutants via common physical, physicochemical, and biological principles such as settling, adsorption, or plant and algae uptake. The efficacy of constructed wetlands for pollutant attenuation varies depending on many factors such as flow rate, pollutant loading, maintenance practices, and design features. In 2018, the culmination of efforts by Clackamas Water Environment Services and others led to the opening of the Carli Creek Water Quality Project, a 15-acre constructed wetland adjacent to Carli Creek, a small, 3500-ft tributary of the Clackamas River in Clackamas County, OR. The combined creek and constructed wetland drain an industrialized, 438-acre, impervious catchment. The wetland consists of a linear series of a detention pond and three bioretention treatment cells, contributing a combined 1.8 acres of treatment area (a 1:243 ratio with the catchment) and 3.3 acre-feet of total runoff storage. In this study, raw pollutant concentrations in runoff were evaluated against International Stormwater BMP database benchmarks and Oregon Water Quality Criteria. Concentration and mass-based reductions were calculated for 10 specific pollutants and compared to daily precipitation totals from a nearby precipitation station. Mass-based reductions were generally higher for all pollutants, largely due to runoff volume reduction on the treatment terrace. Concentration-based reductions were highly variable, and suggested export of certain pollutants (e.g., ammonia), even when reporting on a mass-basis. Mass load reductions on the terrace for total dissolved solids, nitrate+nitrite, dissolved lead, and dissolved copper were 43.3 ± 10%, 41.9 ± 10%, 36.6 ± 13%, and 43.2 ± 16%, respectively. E. coli saw log-reductions ranging from -1.3 — 3.0 on the terrace, and -1.0 — 1.8 in the creek. Oregon Water Quality Criteria were consistently met at the two in-stream sites on Carli Creek for E. coli with one exception, and for dissolved cadmium, lead, zinc, and copper (with one exception for copper). However, dissolved total solids at the downstream Carli Creek site was above the Willamette River guidance value 100 mg/L roughly 71% of the time. The precipitation record during the study was useful for explaining certain pollutant reductions, as several mechanisms are driven by physical processes, however it was not definitive. The historic rain/snow/ice event in mid-February 2021 appeared to impact mass-based reductions for all metals. Qualitatively, precipitation seemed to have the largest effect on nutrient dynamics, specifically ammonia-nitrogen. Determining exact mechanisms of pollutant removals was outside the scope of this study. An improved flow record, more targeted storm sampling, or more comprehensive nutrient profiles could aid in answering important questions on dominant mechanisms of this new constructed wetland. This study is useful in establishing a framework and baseline for understanding this one-of-a-kind regional stormwater treatment project and pursuing further questions in the future.
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