Log in

Relevant bibliographies by topics / DPPE / Journal articles

To see the other types of publications on this topic, follow the link: DPPE.

Journal articles on the topic 'DPPE'

Author: Grafiati

Published: 4 June 2021

Last updated: 2 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'DPPE.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Al-Samrai, Osama'a A. Y., Ahmed S. M. Al-Janabi2, and Eman A. Othman1. "Mixed Ligand Complexes of Hg-tetrazole-thiolate with phosphine, Synthesis and spectroscopic studies." Tikrit Journal of Pure Science 24, no. 5 (2019): 10. http://dx.doi.org/10.25130/j.v24i5.860.

Full text

Abstract:

Seven new complexes [Hg(k1-ptt)2](1), [Hg(k1-ptt)2(dppm)](2), [Hg(k1-ptt)2(dppe)](3), [Hg(k1-ptt)2(dppp)](4), [Hg(k1-ptt)2(dppb)](5), [Hg(k1-ptt)2(dppf)] (6), and [Hg(k1-ptt)2(PPh3)2] (7) have been synthesized and characterized. The reaction of two moles equivalent of 1-Phenyl-1H-tetrazole-5-thiol (Hptt) with one mole equivalent of Hg(oAc)2.xH2O in ethanol solution afford [Hg(k1-ptt)2] (1). Treatment of (1) with one mole equivalent of diphos (diphos : dppm, dppe, dppp, dppb, dppf) or two moles equivalent of PPh3 afforded a complexes of the types [Hg(k1-ptt)2(diphos)] (2-6) or [Hg(k1-ptt)2(PPh3)2] (7). The prepared complexes have been characterized by CHNS elemental analyses, molar conductivity, IR and NMR (1H, 13C and 31P) spectroscopy. In all complexes, the ptt- ligand is bonded through the sulfur atom of deprotonated thiol group, whereas the diphosphine ligands bonded as bidentate chelating and PPh3 bonded as a monodentate, to afford a tetrahedral geometry around the Hg+2 ion.  http://dx.doi.org/10.25130/tjps.24.2019.083

APA, Harvard, Vancouver, ISO, and other styles

2

Qian, Ting-Ting, Yu-Feng Xie, Hua-Tian Shi, Ai-Quan Jia та Qian-Feng Zhang. "New adducts of silver(I) halides, AgX (X = Cl, Br), with bidentate phosphine ligands: syntheses and molecular structures of [Ag3(μ3-Cl)2(μ-dppm)3][PF6], [Ag3(μ3-Br)2(μ-dppm)3][AgBr2], {[Et4N][Ag2 (μ-Br)3(μ-dppe)]}n, [Et4N]2[(AgCl2)2(μ-dppe)], and [(AgCl)2(μ-dppp)2]". Zeitschrift für Naturforschung B 72, № 5 (2017): 327–34. http://dx.doi.org/10.1515/znb-2016-0193.

Full text

Abstract:

AbstractInteraction of AgCl with bis(diphenylphosphino)methane (dppm) in THF/MeCN in the presence of K[PF6] or [Et4N]Br afforded typical trinuclear cationic trigonal-bipyramidal complexes [Ag3(μ3-Cl)2(μ-dppm)3][PF6] (1) or [Ag3(μ3-Br)2(μ-dppm)3][AgBr2] (2), respectively. Treatment of AgBr with bis(diphenylphosphino)ethane (dppe) in THF/MeCN in the presence of [Et4N]Br gave a polymeric complex {[Et4N][Ag2(μ-Br)3(μ-dppe)]}n (3) with a dinuclear {Ag2(μ-Br)3} core. The reaction of AgCl with dppe or bis(diphenylphosphino)propane (dppp) in THF/MeCN in the presence of [Et4N]Cl resulted in the isolation of a dinuclear anionic complex [Et4N]2[(AgCl2)2(μ-dppe)] (4) with one μ-dppe bridge or a dinuclear neutral complex [(AgCl)2(μ-dppp)2] (5) with two μ-dppp bridges and a 12-membered ring, respectively. The structures of complexes 1–5 with the bidentate phosphine ligands were determined by single-crystal X-ray diffraction.

APA, Harvard, Vancouver, ISO, and other styles

3

Smith, Jr., Dale C., Jérémie Cadoret, Laleh Jafarpour, Edwin D. Stevens, and Steven P. Nolan. "Synthetic and solution calorimetric investigations of chelating phosphine ligands in Ru(allyl)2(PP) complexes (PP = diphosphine)." Canadian Journal of Chemistry 79, no. 5-6 (2001): 626–31. http://dx.doi.org/10.1139/v00-164.

Full text

Abstract:

Reaction enthalpies of (COD)Ru(allyl)2 (COD = η4-1,5-cyclooctadiene; allyl = 2-methylpropenyl) with a series of bidentate phosphines (dppm, dppf, dppe, dppb, dppp, depe, dmpe) have been measured by anaerobic solution calorimetry. The relative stability of the resulting complexes is strongly influenced by the electronic donor properties of the bidentate phosphine ligand. Reactions involving ligands that are better σP) donors result in higher enthalpy values and, therefore, more thermodynamically stable complexes. Additionally, the synthesis and characterization of two new ruthenium allyl complexes Ru(allyl)2(dppf) (3) and Ru(allyl)2(depe) (8) and the X-ray crystal structure of 3 are reported.Key words: ruthenium, allyl, solution calorimetry, thermodynamics, X-ray structure.

APA, Harvard, Vancouver, ISO, and other styles

4

Momeni, Badri Z., and Sedigheh Eatezadi. "Pt−Me bond cleavage in the reactions of dimethylplatinum(II) complexes containing chelating phosphine ligands with organotin(IV) chlorides." Canadian Journal of Chemistry 91, no. 12 (2013): 1288–91. http://dx.doi.org/10.1139/cjc-2013-0338.

Full text

Abstract:

Selective Pt−Me bond activation of dimethylplatinum(II) complexes [PtMe2(PP)] (PP = dppm (bis(diphenylphosphino)methane), dppe (1,2-bis(diphenylphosphino)ethane), dppp (1,3-bis(diphenylphosphino)propane)) was achieved by SnMe2Cl2 to yield the corresponding platinum(II) complexes [PtMeCl(PP)] (PP = dppm, dppe, dppp) and cis-[PtCl2(PP)] (PP = dppm, dppp). On the other hand, the reactions of complexes [PtMe2(PP)] (PP = dppm, dppe, dppp) with SnPh3Cl resulted in the selective cleavage of the Pt−Me bond to afford the methylplatinum(II) complexes [PtMeCl(PP)]. Notably, the reaction of [PtMe2(dppm)] with SnMe2Cl2 and SnPh3Cl also gave the ionic A-frame complex [Pt2Me2(μ-Cl)(μ-dppm)2]Cl. The variable-temperature 1H and 31P NMR spectroscopy shows that the cleavage of the Pt−Me bond occurs very rapidly and the short-lived platinum(IV) intermediate is difficult to detect during the reaction. An explanation is presented on the basis of the nature of the strong π-acceptance of the phosphine ligand, which resulted in the formation of a very unstable platinum(IV) intermediate.

APA, Harvard, Vancouver, ISO, and other styles

5

Kawano, Hiroyuki, Rie Tanaka, Tomoko Fujikawa, Katsuma Hiraki, and Masayoshi Onishi. "Novel Dihydridoruthenium(II) Complexes with Chelating Diphosphine Ligands, RuH2(CO)(diphosphine)(PPh3) (diphosphine = dppe, dppp, dppb, and dppf)." Chemistry Letters 28, no. 5 (1999): 401–2. http://dx.doi.org/10.1246/cl.1999.401.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Choy, Tak-Kee, Chih-Yang Wang, Nam Nhut Phan, et al. "Identification of Dipeptidyl Peptidase (DPP) Family Genes in Clinical Breast Cancer Patients via an Integrated Bioinformatics Approach." Diagnostics 11, no. 7 (2021): 1204. http://dx.doi.org/10.3390/diagnostics11071204.

Full text

Abstract:

Breast cancer is a heterogeneous disease involving complex interactions of biological processes; thus, it is important to develop therapeutic biomarkers for treatment. Members of the dipeptidyl peptidase (DPP) family are metalloproteases that specifically cleave dipeptides. This family comprises seven members, including DPP3, DPP4, DPP6, DPP7, DPP8, DPP9, and DPP10; however, information on the involvement of DPPs in breast cancer is lacking in the literature. As such, we aimed to study their roles in this cancerous disease using publicly available databases such as cBioportal, Oncomine, and Kaplan–Meier Plotter. These databases comprise comprehensive high-throughput transcriptomic profiles of breast cancer across multiple datasets. Furthermore, together with investigating the messenger RNA expression levels of these genes, we also aimed to correlate these expression levels with breast cancer patient survival. The results showed that DPP3 and DPP9 had significantly high expression profiles in breast cancer tissues relative to normal breast tissues. High expression levels of DPP3 and DPP4 were associated with poor survival of breast cancer patients, whereas high expression levels of DPP6, DPP7, DPP8, and DPP9 were associated with good prognoses. Additionally, positive correlations were also revealed of DPP family genes with the cell cycle, transforming growth factor (TGF)-beta, kappa-type opioid receptor, and immune response signaling, such as interleukin (IL)-4, IL6, IL-17, tumor necrosis factor (TNF), and interferon (IFN)-alpha/beta. Collectively, DPP family members, especially DPP3, may serve as essential prognostic biomarkers in breast cancer.

APA, Harvard, Vancouver, ISO, and other styles

7

Kareem, Ola M. Abdul, and Hayfaa M. Jirjes. "Synthesis and characterization of new mixed ligand complexes of Zn (II) and Hg (II) with dithiocarbamate and phosphines." Tikrit Journal of Pure Science 25, no. 1 (2020): 59. http://dx.doi.org/10.25130/j.v25i1.937.

Full text

Abstract:

Complexes of the type [M (Et2DTC)2]2 [M= Zn(1) or Hg(2)] were prepared from the reaction of mercury acetate or zinc acetate with sodium diethyldithiocarbamate trihydrate (NaEt2DTC.3H2O) in (1:2) molar ratio (metal: ligand) in mixture of MeOH and H2O as a solvent. Treatment equal molar of (1) or (2) with diphosphine ligands {where diphos: bis (diphenylphosphino) methane (dppm), 1,2-bis (diphenylphosphino) ethane (dppe) and 1,3-Bis (diphenylphosphino) propane (dppp)} afforded complexes of the type [Zn(Et2DTC)2(dppeO)] (3); [Zn(Et2DTC)2(dpppS)] (4a); [Zn(Et2DTC)2(dppp)] (4b); [Hg(Et2DTC)2(dppm)] (6a); [Hg(Et2DTC)2(µ-dppm)]2(6b); [Hg(Et2DTC)2(dppe)](7) and [Hg(Et2DTC)2(dppp)](8), or with two moles of triphenylphosphine (PPh3) afforded a complexes of the type [M(κ1-Et2DTC)2(PPh3)2] (5a, 9a) and [M(κ2-Et2DTC)2(PPh3)2] (5b, 9b) {M= Zn, Hg}. The prepared complexes were fully characterized by different technics such as IR, NMR (1H and 31P) spectroscopy, elemental analysis, and molar conductivity. Characterization data showed that the (Et2DTC) ligand in all of the prepared complexes was coordinated with metal through the sulfur atoms of CSS- group. The geometry of the complexes (1-9) were tetrahedral around the Zn(II) and Hg(II) ions, except isomers 5b and 9b are octahedral geometry. .  http://dx.doi.org/10.25130/tjps.25.2020.011

APA, Harvard, Vancouver, ISO, and other styles

8

Stone, Jeremy, David Jago, Alexandre Sobolev, Mark Spackman, and George Koutsantonis. "Facile Synthesis of Pentamethylcyclopentadienyl Ruthenium Half-Sandwich Complexes by Naphthalene Displacement." Australian Journal of Chemistry 71, no. 4 (2018): 289. http://dx.doi.org/10.1071/ch18024.

Full text

Abstract:

Ruthenium half-sandwich complexes are central in a wide range of diverse applications in the field of organometallic chemistry. As such, exploration of their preparation and reactivity is crucial for development of their chemistry. Herein, we present alternative synthetic methods for the preparation of Cp*Ru(dppm)Cl, Cp*Ru(dppe)Cl, Cp*Ru(dppf)Cl, [Cp*Ru(COD)(MeCN)]BF4, and [Cp*Ru(bpy)(MeCN)]BF4 (dppm = 1,2-bis(diphenylphosphino)methane; dppe = 1,2-bis(diphenylphosphino) ethane; dppf = 1,2-bis(diphenylphosphino)ferrocene; COD = 1,5-cyclooctadiene; bpy= 2,2′-bipyridine), starting from the easily accessible [Cp*Ru(η6-C10H8)]BF4. The single-crystal X-ray structure determinations for [Cp*Ru(COD)(MeCN)]BF4, and [Cp*Ru(bpy)(MeCN)]BF4 are also presented.

APA, Harvard, Vancouver, ISO, and other styles

9

Pombeiro, A. J. L., A. Hills, D. L. Hughes, and R. L. Richards. "[MoH4(dppe)2].thf (dppe = Ph2PCH2CH2PPh2; thf = Tetrahydrofuran)." Acta Crystallographica Section C Crystal Structure Communications 51, no. 1 (1995): 23–26. http://dx.doi.org/10.1107/s0108270194007559.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Gluyas, Josef B. G., Neil J. Brown, Julian D. Farmer, and Paul J. Low. "Optimised Syntheses of the Half-Sandwich Complexes FeCl(dppe)Cp*, FeCl(dppe)Cp, RuCl(dppe)Cp*, and RuCl(dppe)Cp." Australian Journal of Chemistry 70, no. 1 (2017): 113. http://dx.doi.org/10.1071/ch16322.

Full text

Abstract:

Thanks to their synthetic versatility, the half-sandwich metal chlorides MCl(dppe)(η5-C5R5) [M = Fe, Ru; dppe = 1,2-bis(diphenylphosphino)ethane, R = H (cyclopentadiene, Cp), CH3 (pentamethylcyclopentadiene, Cp*)] are staple starting materials in many organometallic laboratories. Here we present an overview of the synthetic methods currently available for FeCl(dppe)Cp*, FeCl(dppe)Cp, RuCl(dppe)Cp*, and RuCl(dppe)Cp, and describe in detail updated and optimised multigram syntheses of all four compounds.

APA, Harvard, Vancouver, ISO, and other styles

11

Ali Mohamad, Hikmat. "Synthesis and Anticancer Activity of Mixed Ligand, Cobalt (II), Nickel (II), Manganese (II) Complexes of Tertiary Diphosphines with Dithizone (H2dz)." Oriental Journal of Chemistry 34, no. 4 (2018): 1919–25. http://dx.doi.org/10.13005/ojc/3404027.

Full text

Abstract:

The one-pot synthesis reaction of one mole MCl2.nH2O, where M= Co(II), Ni(II), Mn(II) ,with one mole of 1,5-diphenylthiocarbazone (dithizone;H2dz), of 1,1-bis(diphenyl phosphine)ferrocene (dppf) and 1,2-bis(diphenyl phosphine) ethane (dppe) gave colored complexes of; [Co(Hdz)(k2-dppf)]Cl, [Ni(Hdz)(k2-dppf)]Cl, [Ni(Hdz)(k2-dppe)]Cl and [Mn(Hdz)(k2-dppf)]Cl. The synthesized complexes have been identified by using 1HNMR, IR, UV-Vis spectroscopy, micro elemental analysis and molar conductance. All complexes were tested for their anticancer activities on Human breast cancer cell line CAL5. The results showed that [Ni(Hdz)(k2-dppe)]Cl and[Mn(Hdz)(k2-dppf)]Cl have a highest activities than cisplatin in compared to; [Co(Hdz)(k2-dppf)]Cl, [Ni(Hdz)(k2-dppf)]Cl.

APA, Harvard, Vancouver, ISO, and other styles

12

Aly, Aref A. M., та Hubert Schmidbaur. "Preparation and Properties of ω-Phosphino-phosphoniocarboxylic Acids and their Betaines". Zeitschrift für Naturforschung B 46, № 6 (1991): 775–78. http://dx.doi.org/10.1515/znb-1991-0612.

Full text

Abstract:

In an attempt to provide phosphorus analogues of aminocarboxylic acids and their betaines, α, ω-bis(diphenylphosphino)alkanes (dppm, dppe, dppp, dppb) were converted into ω-phosphino-phosphoniocarboxylates and diphosphonio-biscarboxylates. While the reactions with haloacetic acids or haloacetates only lead to methylphosphonium derivatives owing to decarboxylation of the intermediates, β-chloropropionic acids converts Ph2P(CH2)nPPh2 compounds into the target products Ph2PCH2PPh2+(CH2)2COOHCI- (1) and CH2[PPh2(CH2)2COOH]22Cl- (2), for n = 1. For n = 2, 3 and 4, only the analogues of 2 could be prepared (3-5). Treatment of 1 and 2 with sodium bicarbonate afforded the corresponding betaines Ph2PCH2PPh2+CH2CH2COO- (isolated as a dihydrate 6) and CH2[PPh2+CH2CH2COO-]2 (isolated as the tetrahydrate 7).

APA, Harvard, Vancouver, ISO, and other styles

13

Subasi, Elif, Fadime Ugˇur (Sarikahya), and Ozan Sanlı Şentürk. "Photochemical reactions of Re(CO)5Br with Ph2P(CH2)nPPh2(n = 1, dppm; 2, dppe; 3, dppp)." Transition Metal Chemistry 29, no. 1 (2004): 16–18. http://dx.doi.org/10.1023/b:tmch.0000014476.17386.6b.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Machura, B., R. Kruszynski, and M. Jaworska. "The reactivity of [ReBr3(MeCN)(dppe)] towards gaseous nitric oxide. The X-ray structure of [ReBr3(MeCN)(dppe)] and [ReBr3(NO)(dppe)]0.57[ReOBr3(dppe)]0.43 and DFT calculations for [ReBr3(NO)(dppe)] and [ReOBr3(dppe)]." Journal of Molecular Structure 740, no. 1-3 (2005): 107–17. http://dx.doi.org/10.1016/j.molstruc.2005.01.038.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Liu, Clive, Patricia Marshall, Ian Schreibman, Ann Vu, Weiming Gai, and Michael Whitlow. "Interaction Between Terminal Complement Proteins C5b-7 and Anionic Phospholipids." Blood 93, no. 7 (1999): 2297–301. http://dx.doi.org/10.1182/blood.v93.7.2297.407k19_2297_2301.

Full text

Abstract:

We have recently shown that C5b-6 binds to the erythrocyte membrane via an ionic interaction with sialic acid before the addition of C7 and subsequent membrane insertion. In this study we assessed the role of anionic lipids in the binding of the terminal complement proteins to the membrane and the efficiency of subsequent hemolysis. Human erythrocytes were modified by insertion of dipalmitoyl phosphatidylcholine (DPPC), dipalmitoyl phosphatidylserine (DPPS), dipalmitoyl phosphatidylethanolamine (DPPE), or dipalmitoyl phosphatidic acid (DPPA). Lipid incorporation and the hemolytic assays were done in the presence of 100 μmol/L sodium orthovanadate to prevent enzymatic redistribution of lipid. We found that the neutral lipids, DPPC and DPPE, did not affect C5b-7 uptake or hemolysis by C5b-9. In contrast, the two acidic phospholipids, DPPS and DPPA, caused a dose-dependent increase in both lysis and C5b-7 uptake. We conclude that the presence of anionic lipids on the exterior face of the membrane increases C5b-7 uptake and subsequent hemolysis. It is known that sickle cell erythrocytes have increased exposure of phosphatidylserine on their external face and are abnormally sensitive to lysis by C5b-9. The data presented here provide a plausible mechanism for this increased sensitivity.

APA, Harvard, Vancouver, ISO, and other styles

16

Del Zotto, Alessandro, Antonio Mezzetti, Veronica Novelli, Pierluigi Rigo, Maurizio Lanfranchi, and Antonio Tiripicchio. "Nickel nitrosyl complexes with diphosphines. The crystal and molecular structure of [(dppe)(ON)Ni(µ-dppe)Ni(NO)(dppe)][BF4]2(dppe = Ph2PCH2CH2PPh2)." J. Chem. Soc., Dalton Trans., no. 3 (1990): 1035–42. http://dx.doi.org/10.1039/dt9900001035.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Volkov, Oleg, Nigam P. Rath, and Lawrence Barton. "Chemistry on the Rhodacarborane Cluster [9,9-(PPh3)-nido-9,7,8-RhC2B8H11]: Formation of Bidentate Phosphine and Bimetallic Derivatives." Collection of Czechoslovak Chemical Communications 67, no. 6 (2002): 769–82. http://dx.doi.org/10.1135/cccc20020769.

Full text

Abstract:

The electronically unsaturated rhodacarborane [9,9-(PPh3)2-nido-9,7,8-RhC2B8H11] (1), reacts with Ph2PCH2PPh2 (dppm) to afford [9,9-(dppm-κ2P)-9-(dppm-κP)-nido-9,7,8-RhC2B8H11] (3), in which the Rh-bonded PPh3 ligands have been replaced by two dppm ligands, one in a bidentate mode and the second in a unidentate mode with a free PPh2 end. The structure of 3 is similar to the related, and isoelectronic, species [8,8-(dppm-κ2P)-8-(dppm-κP)-nido-8,7-RhSB9H10] (4), but with a difference in the orientation of the ligands. Reaction of 1 with Ph2P(CH2)2PPh2 (dppe) affords a species tentatively identified as [9,9-(dppe-κ2P)-9-(dppe-κP)-nido-9,7,8-RhC2B8H11] (5). If allowed to react with [Ru(η6-p-cym)Cl2]2, (3) affords [9,9-{Ru(η6-p-cym)dppm-κ2P-(μ-Cl)2}-nido-9,7,8-RhC2B8H11] (6) containing the group [(μ-Cl)2Ru(η6-p-cym)dppm] that coordinates in a multidentate mode to Rh. Compounds 3 and 6 are characterized by 11B, 1H and 31P NMR spectroscopy, elemental analysis and X-ray structure determinations.

APA, Harvard, Vancouver, ISO, and other styles

18

Keough, K. M. W., M. W. Hawco, and C. S. Parsons. "The effect of methylation of phosphatidylethanolamine on the behaviour of lipid monolayers at the air–water interface." Biochemistry and Cell Biology 66, no. 5 (1988): 405–17. http://dx.doi.org/10.1139/o88-049.

Full text

Abstract:

Monolayers of DPPE and its N-methylated derivatives including DPPC have been investigated at 23 and 37 °C using a modified Langmuir–Wilhelmy surface balance. The monolayers have been subjected to dynamic compression and expansion, and some characteristics of the surfaces have been determined. The minimum surface tension attained by surfaces containing the lipids (maximum surface pressures sustained by the films) depended on the extent of methylation of the head group. Monolayers of DPPE or N-MeDPPE collapsed at surface tensions of 12–16 mN∙m−1, whereas those containing N,N-diMeDPPE and DPPC could be compressed to near zero surface tension. The areas per molecule occupied by these lipids under high compression varied slightly and not systematically with head-group methylation. Monolayers containing mixtures of DPPC and DPPE were also studied under the same conditions. The monolayers showed some deviation from the behaviour expected if they were to have characteristics of ideally mixed systems. The minimum surface tensions attained suggested that monolayers containing 50 mol% or more DPPC might be further enriched during compression by some selective exclusion of the DPPE. At high surface pressures, some positive deviations in nominal areas per molecule from that expected for ideal mixing were observed in the monolayers made with 50 mol% or more DPPC. These deviations might be caused by packing disruptions associated with the explosion of lipid from the films.

APA, Harvard, Vancouver, ISO, and other styles

19

Liu, Clive, Patricia Marshall, Ian Schreibman, Ann Vu, Weiming Gai, and Michael Whitlow. "Interaction Between Terminal Complement Proteins C5b-7 and Anionic Phospholipids." Blood 93, no. 7 (1999): 2297–301. http://dx.doi.org/10.1182/blood.v93.7.2297.

Full text

Abstract:

Abstract We have recently shown that C5b-6 binds to the erythrocyte membrane via an ionic interaction with sialic acid before the addition of C7 and subsequent membrane insertion. In this study we assessed the role of anionic lipids in the binding of the terminal complement proteins to the membrane and the efficiency of subsequent hemolysis. Human erythrocytes were modified by insertion of dipalmitoyl phosphatidylcholine (DPPC), dipalmitoyl phosphatidylserine (DPPS), dipalmitoyl phosphatidylethanolamine (DPPE), or dipalmitoyl phosphatidic acid (DPPA). Lipid incorporation and the hemolytic assays were done in the presence of 100 μmol/L sodium orthovanadate to prevent enzymatic redistribution of lipid. We found that the neutral lipids, DPPC and DPPE, did not affect C5b-7 uptake or hemolysis by C5b-9. In contrast, the two acidic phospholipids, DPPS and DPPA, caused a dose-dependent increase in both lysis and C5b-7 uptake. We conclude that the presence of anionic lipids on the exterior face of the membrane increases C5b-7 uptake and subsequent hemolysis. It is known that sickle cell erythrocytes have increased exposure of phosphatidylserine on their external face and are abnormally sensitive to lysis by C5b-9. The data presented here provide a plausible mechanism for this increased sensitivity.

APA, Harvard, Vancouver, ISO, and other styles

20

Carmichael, Duncan, Peter B. Hitchcock, John F. Nixon, and Alan Pidcock. "Generation and interconversions of the di- and tri-nuclear platinum complexes [Pt2H2(dppe)2], [Pt2H3(dppe)2]+, and [Pt3H3(dppe)3]+. Crystal and molecular structure of [Pt3H3(dppe)3]+[BEt4]–, (dppe = Ph2PCH2CH2PPh2)." J. Chem. Soc., Chem. Commun., no. 23 (1988): 1554–56. http://dx.doi.org/10.1039/c39880001554.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Chen, Xiangke, Zishuai Huang, Wei Hua, Hardy Castada, and Heather C. Allen. "Reorganization and Caging of DPPC, DPPE, DPPG, and DPPS Monolayers Caused by Dimethylsulfoxide Observed Using Brewster Angle Microscopy." Langmuir 26, no. 24 (2010): 18902–8. http://dx.doi.org/10.1021/la102842a.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Park, Yeseul, and Jin-Won Park. "Specific Detection of PE-Included Vesicles Using Cyclic Voltammetry." Applied Sciences 11, no. 8 (2021): 3660. http://dx.doi.org/10.3390/app11083660.

Full text

Abstract:

The binding between cinnamycin and the phosphatidylethanolamine (PE)-included vesicles was monitored using cyclic voltammetry (CV) measurements and interpreted in terms of the composition of the vesicles and the monolayer binding site. The monolayer was composed of pure 11-mercapto-1-undecanol (MUD) to 90% MUD/10% 16-mercaptohexadecanoic acid (MHA) on a gold surface. Cinnamycin was immobilized on each monolayer. The vesicles, prepared at the desired ratio of the phospholipids, were injected on the cinnamycin-immobilized surface. CV experiments were performed for each step. For the pure-dipalmitoylphosphatidyl-choline (DPPC) vesicles on all of monolayers and the DPPC/dipalmitoylphosphatidyl-ethanolamine (DPPE) vesicles on the pure-MUD monolayer, the electric property of the surface was little changed. However, the vesicles made with 90% DPPC/10% DPPE on the monolayer prepared with 99% MUD/1% MHA to 90% MUD/10% MHA showed a consistent decrease in the CV response. Additionally, in the 95% DPPC/5% DPPE vesicles and the 99.5% MUD/0.5% MHA monolayer, variances in the responses were observed.

APA, Harvard, Vancouver, ISO, and other styles

23

Byabartta, Prithwiraj. "Organometallic gold(I)-pentafluorophenyl-P, O, As, S, TPA, dppm, dppe, dppa-coordinating-phosphines: synthesis and detailed spectroscopic characterisation." Transition Metal Chemistry 32, no. 6 (2007): 716–26. http://dx.doi.org/10.1007/s11243-007-0241-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Petrov, P. A., M. R. Ryzhikov, N. V. Kuratieva, and S. N. Konchenko. "Cluster [Re3S5(Dppe)3]+ and its oxidation to [Re3S4(SO2)(Dppe)3]+." Russian Journal of Coordination Chemistry 42, no. 3 (2016): 196–200. http://dx.doi.org/10.1134/s1070328416020056.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Петров, П. А., М. Р. Рыжиков, Н. В. Куратьева та С. Н. Конченко. "Кластер [Re3S5(Dppe)3]+и его окисление до [Re3S4(SO2)(Dppe)3]+". Координационная химия 42, № 3 (2016): 173–77. http://dx.doi.org/10.7868/s0132344x16020055.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Basallote, Manuel G., Joaquín Durán, M. Jesús Fernández-Trujillo, and M. Angeles Máñez. "Kinetics of protonation of cis-[FeH2(dppe)2]: formation of the dihydrogen complex trans-[FeH(H2)(dppe)2]+ (dppe = Ph2PCH2CH2PPh2)." Journal of the Chemical Society, Dalton Transactions, no. 13 (1998): 2205–10. http://dx.doi.org/10.1039/a800916c.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Barthazy, Peter, Diego Broggini, and Antonio Mezzetti. "Making a 16-electron bromo (or iodo) complex of ruthenium(II) and a CF bond in one pot." Canadian Journal of Chemistry 79, no. 5-6 (2001): 904–14. http://dx.doi.org/10.1139/v01-049.

Full text

Abstract:

The 16e bromo or iodo complexes [RuX(dppp)2]+ (dppp = 1,3-bis(diphenylphosphino)propane, X = Br (1c), I (1d)) and [RuX(dppe)2]+ (dppe = 1,2-bis(diphenylphosphino)ethane, X = Br (2c), I (2d)) have been prepared exploiting the reaction of the fluoro complexes [RuF(dppp)2]+ (1a) and [Tl(µ-F)2Ru(dppe)2]+ (3) with activated alkyl bromides or iodides. The X-ray structures of 1c, 1d, 2c, and 2d suggest that the distortion of the Y-shaped trigonal-bipyramidal structure of [MX(P∩P)2]+ is possibly related to the formation of intramolecular hydrogen bonds between the halide ligand and the ortho-hydrogen atoms of the neighbouring phenyl rings. The five-coordinate species 1c, 1d, 2c, and 2d react with H2 to form the dihydrogen complexes [RuX(η2-H2)(P∩P)2]+. The reaction of the dppp derivatives 1c and 1d with H2 (P = 1 atm, 1 atm = 101.322 kPa) is an equilibrium. Quantitative formation of [RuBr(η2-H2)(dppp)2] (4c) is obtained under H2 pressure (100 bar, 1 bar = 100 kPa), whereas the iodo analogue is not stable under analogous conditions. The less crowded dppe derivatives 2c and 2d react quantitatively with H2 under ambient pressure. The iodo and bromo derivatives [RuX(η2-H2)(P∩P)2]+ contain elongated dihydrogen ligands, as indicated by their transverse relaxation times T1 (min). The present data suggest that Cl, Br, and I have similar donor properties in these dihydrogen complexes, and that the different chemical behaviour in the Cl, Br, I series is mainly a result of steric effects.Key words: 16e complexes, ruthenium, fluoro complexes, bromo complexes, iodo complexes, dihydrogen complexes.

APA, Harvard, Vancouver, ISO, and other styles

28

Foley, Janet, Raymond C. Fort, Katherine McDougal, Mitchell R. M. Bruce, and Alice E. Bruce. "Electronic and Steric Effects in Gold(I) Phosphine Thiolate Complexes." Metal-Based Drugs 1, no. 5-6 (1994): 405–17. http://dx.doi.org/10.1155/mbd.1994.405.

Full text

Abstract:

The unusual yellow color of Au2(dppm)(SR)2 (R = 4-tolyl; dppm = diphenylphosphinomethane) is attributed to a red-shift in the S→Au charge transfer caused by destabilization of the sulfur highest occupied molecular orbital (HOMO). Variable temperature experiments show two broad bands at -80°C in the P31{H1} NMR spectrum of Au2(dppm)(SR)2 and the activation energy for interconversion is 10 kcal/mol. Only one sharp band is observed down to -80°C in the spectrum of the white complex, Au2(dppe)(SR)2 (dppe = diphenylphosphinoethane). Molecular mechanics calculations on Au2(dppm)(SR)2 and Au2(dppe)(SR)2 reveal that, for Au2(dppe)(SR)2, a series of maxima and minima, separated by 2.5 kcal/mol, occur every 120° which is consistent with rotation around an unhindered carbon-phosphorus single bond. The Au atoms are not within bonding distance in any conformation. Computational results for Au2(dppm)(SR)2 indicate one minimum energy structure in which the Au-P bonds are anti. There is a high energy conformation (9 kcal/mol above the global minimum) where overlap between golds is maximized. The implications of gold-gold bonding in this complex are discussed. The steric influence of the thiolate ligand has been examined by synthesizing a series of dinuclear gold(I) complexes in which the steric properties of the thiolate are varied: Au2(dppm)(SR)2 (R = 2,6-dichlorophenyl; 2,6-dimethylphenyl; 3,5-dimethylphenyl). The 2,6-disubstituted complexes are white, while the 3,5-dimethyl complex is yellow. These results, along with VT-NMR experiments, are consistent with the conclusion that the more sterically-bulky thiolates hinder the close approach of the golds in the dinuclear complexes.

APA, Harvard, Vancouver, ISO, and other styles

29

Schenk, Wolfdieter A., and Thomas Stur. "Elektronenreiche Ruthenium-Thiolat-Komplexe, Synthese und Reaktionen mit Elektrophilen / Electron-Rich Ruthenium Thiolate Complexes, Synthesis and Reactions with Electrophiles." Zeitschrift für Naturforschung B 45, no. 11 (1990): 1495–98. http://dx.doi.org/10.1515/znb-1990-1105.

Full text

Abstract:

Ruthenium thiolates [cpRu(PR′3)2(SR)] (PR′3 = PPh3,1/2 dppe, 1/2 dppm, R = Me, CH2Ph) are obtained from the corresponding chlorides and NaSR. PPh3 is readily exchanged for CO to give the chiral complexes [cpRu(PPh3)(CO)(SR)]. Alkylation with methyl tosylate yields the cations [cpRu(dppe)(SMeR)]+ and [cpRu(PPh3)(CO)(SMeR)]+, which were isolated as their PF6- salts. The neutral carbonyls add dimethyl acetylenedicarboxylate giving five-membered metallocycles.

APA, Harvard, Vancouver, ISO, and other styles

30

Kunin, Amanda J., Edward J. Nanni, and Richard Eisenberg. "Chemical reduction of bis[bis(diphenylphosphino)ethane]rhodium(1+), [Rh(dppe)2]+. Characterization of Rh(dppe)20 and Rh(dppe)2-." Inorganic Chemistry 24, no. 12 (1985): 1852–56. http://dx.doi.org/10.1021/ic00206a031.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Milton Franklin Benial, A., V. Ramakrishnan, and R. Murugesan. "Infrared and laser Raman studies of [Ni(II)(dppe)Cl2] and [Co(III)(dppe)2Cl2]PF6 (dppe=1,2-bis(diphenylphosphino)ethane)." Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 58, no. 8 (2002): 1703–12. http://dx.doi.org/10.1016/s1386-1425(01)00622-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Cybulski, Mateusz K., Jessica E. Nicholls, John P. Lowe, Mary F. Mahon, and Michael K. Whittlesey. "Catalytic Hydrodefluorination of Fluoroarenes Using Ru(IMe4)2L2H2 (IMe4 = 1,3,4,5-Tetramethylimidazol-2-ylidene; L2 = (PPh3)2, dppe, dppp, dppm) Complexes." Organometallics 36, no. 12 (2017): 2308–16. http://dx.doi.org/10.1021/acs.organomet.7b00243.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Pursiainen, Jouni, and Tapani A. Pakkanen. "Synthesis and characterisation of H3Ru3Co(CO)10(dppe) and HRuCo3(CO)10(dppe)." Journal of Organometallic Chemistry 309, no. 1-2 (1986): 187–97. http://dx.doi.org/10.1016/s0022-328x(00)99584-6.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Bryndza, Henry E., Suzanne A. Kretchmar, and Thomas H. Tulip. "Synthesis and reactivity of (dppe)Pt(OMe)2[dppe = 1,2-bis(diphenylphosphino)-ethane]." Journal of the Chemical Society, Chemical Communications, no. 14 (1985): 977. http://dx.doi.org/10.1039/c39850000977.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Adams, Michael C., George A. Koutsantonis, Brian W. Skelton та Allan H. White. "Iron-substituted arsine, [Fe(AsPh2)(dppe)(η-C5H5)]·2thf (dppe = Ph2PCH2CH2PPh2, thf = tetrahydrofuran)". Journal of the Chemical Society, Dalton Transactions, № 19 (1997): 3483–85. http://dx.doi.org/10.1039/a704414c.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Pohl, S., U. Opitz, D. Haase, and W. Saak. "Eisen(II)?Phosphin-Komplexe Synthese und Kristallstrukturen von [Fe2I4(dppe)2], [Fe2(SR)4(dppe)2], [Fe(SR?)2(dppp)] und [Fe(SR)2(PMePh2)2] (dppe = Ph2P(CH2)2PPh2; dppp = Ph2P(CH2)3PPh2; R = 2,4,6-Me3C6H2; R? = 2,4-tBuC6H3)." Zeitschrift f�r anorganische und allgemeine Chemie 621, no. 7 (1995): 1140–46. http://dx.doi.org/10.1002/zaac.19956210705.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Song, Li-Cheng, Ying-Huai Zhu та Qing-Mei Hu. "Synthesis and Characterization of Organochromium Complexes fac-Cr(CO)3(dppe)(η2-C60), fac/mer-Cr(CO)3(dppe)(η2-C60) and fac-Cr(CO)3(L)(dppe) (L = PPh3, 4-MeC5H4N)". Journal of Chemical Research 23, № 1 (1999): 56–57. http://dx.doi.org/10.1177/174751989902300134.

Full text

Abstract:

Reaction of fac-Cr(CO)3(MeCN)(dppe) [dppe = 1,2-bis(diphenylphosphino)ethane] or Cr(CO)4(dppe) with fullerene C60 afforded a single isomer fac-Cr(CO)3(dppe)(η2-C60) and an isomeric mixture of fac/mer-Cr(CO)3(dppe)(η2-C60), whereas the isomer fac-Cr(CO)3(dppe)(η2-C60) reacted with Ph3P or 4-methylpyridine to give single isomers fac-Cr(CO)3(Ph3P)(dppe) and fac-Cr(CO)3(4-MeC5H4N) (dppe), respectively.

APA, Harvard, Vancouver, ISO, and other styles

38

Wang, Qiang, Yang Liu, and Wei Gao. "Preparation of Iodide-Thiolate Bridged Binuclear Ni-Ni Complexes via Versatile Reaction of Labile Ni(II)-S(thiolate) Bond." Advanced Materials Research 554-556 (July 2012): 591–96. http://dx.doi.org/10.4028/www.scientific.net/amr.554-556.591.

Full text

Abstract:

The reaction between Fe(CO)4I2and Ni(SR)2(dppe) affords NiI2(dppe) due to the nucleophilic attack of iodide on the labile Ni-S(thiolate) bonds. The iodide-dithiolate-bridged binuclear Ni-Ni complexes [(dppe)Ni(µ-I)(µ-pdt)Ni(dppe)]I is readily prepared from the reaction between [NiI2(dppe)] and [Ni(pdt)(dppe)] [dppe = 1,2-bis(diphenyl phosphino)-ethane; pdt = 1,3-propane-dithiolate] in CH2Cl2as a result of attack on Ni-I bond by the lone pairs of electrons on thiolato sulfur donors. The reaction between [FeCp(CO)2I] and [Ni(pdt)(dppe)] in CH2Cl2processes extremely slowly. However, upon metathesis with NH4PF6, the iodide-thiolate bridged binuclear Ni-Ni complexes [(dppe)Ni(µ-I)(µ-pdt)Ni(dppe)]PF6is formed from the reaction of iodide and the Ni(II)-S bonds. The reaction between [NiCl2(dppe)] and NH4PF6and [Ni(pdt)(dppe)] gives a binuclear complex [(dppe)Ni(µ-pdt)Ni(dppe)]PF6without a halide-bridge. These results suggest that the reactivity of Ni-SR bonds in the Ni-thiolate-phosphine complexes is tunable with regard to the electronic environment of second metal ion and the different reactivity of iodide moiety. Electrochemical and crystallographic results are also analyzed for relevant compounds.

APA, Harvard, Vancouver, ISO, and other styles

39

Bryan, Jeffrey C., Anthony K. Burrell, and Gregory J. Kubas. "[TcCl(CS)(dppe)2]·C6H6." Acta Crystallographica Section E Structure Reports Online 57, no. 1 (2000): m23—m24. http://dx.doi.org/10.1107/s1600536800019486.

Full text

Abstract:

The title compound, chlorobis[1,2-ethanediylbis(diphenylphosphine)-P,P′](thiocarbonyl-C)technetium benzene solvate, [TcCl(C46H42P4)(CS)]·C6H6, was obtained as one of two Tc-containing products isolated from the reaction between CS2and the electron-deficient complex [TcCl(dppe)2], where dppe is 1,2-ethanediylbis(diphenylphosphine). The structure exhibits an unusually short Tc—C distance [1.819 (6) Å], suggesting some multiple-bond character.

APA, Harvard, Vancouver, ISO, and other styles

40

Leekumjorn, Sukit, and Amadeu K. Sum. "Molecular Simulation Study of Structural and Dynamic Properties of Mixed DPPC/DPPE Bilayers." Biophysical Journal 90, no. 11 (2006): 3951–65. http://dx.doi.org/10.1529/biophysj.105.076596.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Kienle, Daniel F., João V. de Souza, Erik B. Watkins, and Tonya L. Kuhl. "Thickness and refractive index of DPPC and DPPE monolayers by multiple-beam interferometry." Analytical and Bioanalytical Chemistry 406, no. 19 (2014): 4725–33. http://dx.doi.org/10.1007/s00216-014-7866-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Fenske, Dieter, Timo Langetepe, Manfred M Kappes, Oliver Hampe, and Patrick Weis. "Selenverbrückte Gold(I)-Komplexkationen [Au10Se4(dppm)4]2+ und [Au18Se8(dppe)6]2+." Angewandte Chemie 112, no. 10 (2000): 1925–28. http://dx.doi.org/10.1002/(sici)1521-3757(20000515)112:10<1925::aid-ange1925>3.0.co;2-q.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Rigos, Carolina Fortes, Hérica de Lima Santos, Richard John Ward, and Pietro Ciancaglini. "Lipid Bilayer Stabilization of the Na,K-ATPase Reconstituted in DPPC/DPPE Liposomes." Cell Biochemistry and Biophysics 44, no. 3 (2006): 438–45. http://dx.doi.org/10.1385/cbb:44:3:438.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Peringer, Paul, та Maria Lusser. "Unusual mercury-phosphorus coupling constants in the mercury(II) triphosphine complexes [Hg(η2-LL)(η1-dppm)2+ (LL = dppe OR dppp)". Polyhedron 6, № 3 (1987): 655–57. http://dx.doi.org/10.1016/s0277-5387(00)81040-2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Eglin, Judith L., Laura T. Smith, Edward J. Valente та Jeffrey D. Zubkowski. "The synthesis and characterization of trans-ReCl2(dppe)2 and α-Re2Cl4(dppe)2". Inorganica Chimica Acta 268, № 1 (1998): 151–57. http://dx.doi.org/10.1016/s0020-1693(97)05726-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Zhou, Yi-Feng, Li-Hong Huang, Xiao-Hong Chen, Ji-Dong Lou, and Xiu Lian Lu. "Synthesis, Characterization, and Structure of Ruthenium Complex Ru(dppe)2C2O4 (dppe = Ph2P(CH2)2PPh2)." Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry 43, no. 9 (2013): 1228–30. http://dx.doi.org/10.1080/15533174.2011.609857.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Sivasankar, C., M. Nethaji, and A. G. Samuelson. "Synthesis of the first polymeric Cu(I) dppe (dppe=1,2-bis(diphenylphosphino)ethane) complexes." Inorganic Chemistry Communications 7, no. 2 (2004): 238–40. http://dx.doi.org/10.1016/j.inoche.2003.11.011.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Bryndza, Henry E., Joseph C. Calabrese, Marianne Marsi, D. Christopher Roe, Wilson Tam, and John E. Bercaw. ".beta.-Hydride elimination from methoxo vs. ethyl ligands: thermolysis of (DPPE)Pt(OCH3)2, (DPPE)Pt(CH2CH3)(OCH3) and (DPPE)Pt(CH2CH3)2." Journal of the American Chemical Society 108, no. 16 (1986): 4805–13. http://dx.doi.org/10.1021/ja00276a018.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Dennehy, Mariana, Oscar V. Quinzani, Sandra D. Mandolesi та Robert A. Burrow. "Coinage metals ternary tiosaccharinates: Synthesis, characterization and crystal structures of [Ag(tsac)(dppe)(CH3CN)]n and [{Cu(tsac)(dppe)}2(μ-dppe)]·4CH3CN". Journal of Molecular Structure 998, № 1-3 (2011): 119–25. http://dx.doi.org/10.1016/j.molstruc.2011.05.020.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

QI, Shu Y., Pierre J. RIVIERE, Jerzy TROJNAR, Jean-Louis JUNIEN, and Karen O. AKINSANYA. "Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases." Biochemical Journal 373, no. 1 (2003): 179–89. http://dx.doi.org/10.1042/bj20021914.

Full text

Abstract:

Two dipeptidyl peptidase IV (DPPIV, DPP4)-related proteins, DPP8 and DPP9, have been identified recently [Abbott, Yu, Woollatt, Sutherland, McCaughan, and Gorrell (2000) Eur. J. Biochem. 267, 6140–6150; Olsen and Wagtmann (2002) Gene 299, 185–193; Qi, Akinsanya, Riviere, and Junien (2002) Patent application WO0231134]. In the present study, we describe the cloning of DPP10, a novel 796-amino-acid protein, with significant sequence identity to DPP4 (32%) and DPP6 (51%) respectively. We propose that DPP10 is a new member of the S9B serine proteases subfamily. The DPP10 gene is located on the long arm of chromosome 2 (2q12.3-2q14.2), close to the DPP4 (2q24.3) and FAP (2q23) genes. The active-site serine residue is replaced by a glycine residue in DPP10, resulting in the loss of DPP activity. The serine residue is also replaced in DPP6, which lacks peptidase activity. DPP8 and DPP9 share an identical active site with DPP4 (Gly-Trp-Ser-Tyr-Gly). In contrast with the previous results suggesting that DPP9 is inactive, we show that DPP9 is a DPP, hydrolysing Ala-Pro-(7-amino-4-methyl-coumarin) with similar pH-specificity and protease-inhibitor-sensitivity to those of DPP4 and DPP8. Northern-blot analysis shows that whereas DPP8 and DPP9 are widely expressed, DPP10 is expressed mainly in the brain and pancreas. DPP6, which has the highest amino acid identity with DPP10, has been shown previously [Nadal, Ozaita, Amarillo, de Miera, Ma, Mo, Goldberg, Misumi, Ikehara, Neubert et al. (2003) Neuron 37, 449–461] to associate with A-type K+ channel subunits, modulating their transport and function in somatodendritic compartments of neurons. It is possible that DPP10 is involved in similar functions in the brain. Elucidation of the physiological or pathophysiological role of DPP8, DPP9 and DPP10 and characterization of their structure–function relationships will add impetus to the development of inhibitor molecules for pharmacological or therapeutic use.

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!