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1

Martínez, Sarrà Ester. "Characterization of Dental Pulp Pluripotent-like Stem Cells (DPPSC) and their mesodermal differentiation potential." Doctoral thesis, Universitat Internacional de Catalunya, 2017. http://hdl.handle.net/10803/402610.

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Dental pulp represents an easily accessible autologous source of adult stem cell populations. Among them, a population named dental pulp pluripotent-like stem cells (DPPSC) has been isolated from the dental pulp of human third molars and express pluripotency markers such as OCT3/4 and SOX2. DPPSC show pluripotent-like behaviour differentiating in vitro into tissues of the three embryonic layers and being able to form teratoma-like structures. This population also represents a source of adult stem cells without the ethical controversy or safety issues that are associated with the use of embryon
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Hategan, Iulia Emilia. "Regeneración de tejido periodontal in vitro con células madre pluripotenciales de la pulpa dental (DPPSC) del tercer molar." Doctoral thesis, Universitat Internacional de Catalunya, 2016. http://hdl.handle.net/10803/392650.

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El periodonto está formado por varios tejidos: la encía, el ligamento periodontal, el cemento radicular y el hueso alveolar. El periodonto tiene dos funciones fundamentales: protección e inserción. La función de protección la realizan la encía y el epitelio de unión, mientras que la función de inserción se desempeña a través del ligamento periodontal, el cemento radicular y el hueso alveolar.- El ligamento periodontal es un tejido celular altamente vascularizado que rodea la raíz del diente. Se compone por haces de fibras de tejido conectivo fibroso que unen el cemento radicular y la pared d
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Chatakun, Punjamaporn. "The Effect of 5 Proteins On DPPSC (Dental Pulp Pluripotent Stem Cells) For Osteoblast Differentiation Proliferation In 3D." Doctoral thesis, Universitat Internacional de Catalunya, 2014. http://hdl.handle.net/10803/277382.

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Bone-tissue engineering is a therapeutic target in the field of dental implant and orthopaedic surgery. It is therefore essential to find a microenvironment that enhances the growth and differentiation of osteoblasts both from mesenchymal stem cells (MSCs) and those derived from dental pulp (DPSC). The aim of this research is to determine the relationship among the proteins fibronectin (FN), bone morphogenetic protein 2 (BMP2) osteopontin (OPN), tenascin C (TNC) and bone sialoprotein (BSP) and their ability to coat different types of biomaterials and surfaces to enhance osteoblast differentiat
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Núñez, Toldrà Raquel. "Osteogenic differentiation strategies of Dental Pulp Pluripotent-like Stem Cells (DPPSC) for their potential application in Bone Tissue Engineering." Doctoral thesis, Universitat Internacional de Catalunya, 2017. http://hdl.handle.net/10803/454748.

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Actualment, els defectes ossis, ja sigui deguts a traumes o a malalties, afecten a milions de persones a nivell mundial, fet que suposa una demanda constant al sistema sanitari per al reemplaçament o la restitució d’os. En els últims anys, les tècniques de medicina regenerativa i d’enginyeria tissular d’ós que combinen l’ús de biomaterials, cèl·lules i factors de creixement, han esdevingut un recurs terapèutic molt prometedor per al tractament de defectes ossis. Les cèl·lules mare pluripotents poden ser de gran valor en enginyeria tissular degut al seu potencial d’auto-renovació, la seva alta
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Murtra, Sada Maria Cristina. "Evaluación de la Capacidad Osteogénica de las DPPSC (Dental Pulp Pluripotent Stem Cells) sobre diferentes superficies y Biocoating para validar una nueva superfie de Implante Dental." Doctoral thesis, Universitat Internacional de Catalunya, 2014. http://hdl.handle.net/10803/133080.

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Cuando tenemos un implante de Ti convencional, la calidad de su superficie es el pilar fundamental para la osteointegración debido a que sus características topográficas y químicas, son las que controlan la conformación de su capa proteica, y con ello, el sistema de comunicación entre célula-proteína-implante que guiará hacia la deseada osteointegración. Pero en el momento en que a ese implante de Ti convencional se le añade un biocoating, su superficie bioinerte (Ti) se convierte en una superficie bioactiva, donde las biomoléculas que la conforman pasan a ser las activadoras del sistema de co
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Carrió, Bertrán Neus. "Comparación del perfil proteico del ligamento periodontal versus el hueso alveolar con el complejo periodontal diferenciado a partir de las DPPSCs." Doctoral thesis, Universitat Internacional de Catalunya, 2017. http://hdl.handle.net/10803/461770.

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El tratamiento de los defectos infraóseos es uno de los objetivos de la terapia de la enfermedad periodontal. La literatura actual reporta ciertas limitaciones en cuanto a la predictibilidad de las técnicas, por consiguiente, siguen siendo necesarios modelos predictivos y estrategias regenerativas más precisas. Uno de los problemas actuales desde un punto de vista clínico, es el desconocimiento estructural de los tejidos que deseamos regenerar. Definir las proteínas expresadas en el periodonto podría ayudar a establecer estrategias clínicas regenerativas más fiables. El presente estudio
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7

López-Amaya, Clara Inés. "Interaction of Candida rugosa lipase with DPPC liposomes." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/nq27441.pdf.

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8

Kell, Henny. "Wechselwirkung des Lipoheptapeptides Surfactin mit Lipiddoppelschichten aus DMPC und DPPC." [S.l.] : [s.n.], 2006. http://opus.kobv.de/tuberlin/volltexte/2007/1463.

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9

Silva, Gleyce Oliveira [UNESP]. "Efeitos do LRP6 e Frizzled6 na diferenciação endotelial de DPSC." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/136702.

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Made available in DSpace on 2016-04-01T17:54:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-07-31. Added 1 bitstream(s) on 2016-04-01T18:00:34Z : No. of bitstreams: 1 000860768.pdf: 1686526 bytes, checksum: 979e2944f4a6b89a46fd9bb6b0302204 (MD5)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>O objetivo deste estudo foi avaliar a função da via de sinalização Wnt/β- catenina através dos receptores LRP6 e Frizzled6 na diferenciação de células-tronco de polpa dental de dentes permanentes (DPSC) em células endoteliais. DPSC foram transduzidas com marcadores eGFP e
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10

Cigánek, Martin. "Syntéza a studium nových derivátů diketopyrrolopyrrolů (DPPs) pro organickou elektroniku." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2017. http://www.nusl.cz/ntk/nusl-316170.

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This diploma thesis describes organic pigments of diketopyrrolopyrroles (DDPs) possessing properties applicable in attractive and perspective areas of organic electronics and photonics. The modification of the DPP skeleton was performed by nucleophilic substitution by various alkyl chains and 5 series of DPP derivatives were prepared. The regioselectivity of N-alkylation and also the photophysical properties of the prepared derivatives were studied. A key product of this work is the N,N'-ethyladamantyl derivative of DPP, which exhibited ambipolar characteristic with excellent electron mobility
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Souza, João Francisco Ventrici de. "Efeito de materiais particulados em sistemas modelos de biomembranas." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/59/59138/tde-13042012-144908/.

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Neste trabalho foram estudadas algumas propriedades de sistemas miméticos de tensoativos pulmonares (TP) constituídos de dipalmitoilfosfatidilcolina (DPPC) e DPPC/colesterol e suas interações com o material particulado (MP) proveniente da queima da palha da cana-de-açúcar, reconhecido por meio de estudos clínicos como agente agravador de diversas patologias respiratórias. O MP utilizado neste trabalho foi analisado por meio de uma série de técnicas: espalhamento dinâmico de luz (DLS), microscopia eletrônica de varredura acrescida do uso de análise de energia dispersiva de raios X (MEV e MEV-ED
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12

Zander, Thomas [Verfasser], and Andreas [Akademischer Betreuer] Schreyer. "The interaction of DPPC and hyaluronan / Thomas Zander ; Betreuer: Andreas Schreyer." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2016. http://d-nb.info/1116604590/34.

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Zander, Thomas Verfasser], and Andreas [Akademischer Betreuer] [Schreyer. "The interaction of DPPC and hyaluronan / Thomas Zander ; Betreuer: Andreas Schreyer." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2016. http://nbn-resolving.de/urn:nbn:de:gbv:18-80661.

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14

Hamada, Attoumani. "Les propriétés immunitaires des cellules souches de la pulpe dentaire dans un contexte infectieux." Thesis, Aix-Marseille, 2018. http://www.theses.fr/2018AIXM0660/document.

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Les cellules souches de la pulpe dentaire humaine (DPSCs) sont des cellules souches mésenchymateuses (MSCs) isolées de la pulpe dentaire. Les DPSCs sont capables de s’auto-renouveler et se différencier en plusieurs types cellulaires tel que les odontoblastes, les ostéoblastes, les chondrocytes, les neuroblastes et les adipocytes. Les propriétés immunitaires des DPSCs sont de plus en plus étudiées, elles hébergent des récepteurs de types Toll à la surface, possedent une activité immuno-modulatrice.Cependant, les propriétés immunitaires comme celles décrites dans les cellules immunitaires profes
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15

Korkmaz, Filiz. "Biophysical Studies Of Progesterone-model Membrane Interactions." Master's thesis, METU, 2003. http://etd.lib.metu.edu.tr/upload/4/1116060/index.pdf.

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Interactions of progesterone with zwitterionic dipalmitoyl phosphotidylcholine (DPPC) multilamellar liposomes (MLVs) were investigated as a function of temperature and progesterone concentration by using three non-invasive techniques of Fourier transform infrared (FTIR) spectroscopy, turbidity at 440 nm and differential scanning calorimetry (DSC). The results show that 1mol% of progesterone does not induce a significant change in the shape of thermotropic profile of DPPC. However as progesterone concentration increases, the main transition temperature decreases and phase transition curve broad
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16

Ibrahim, Akram Yousif. "A study of DPPC and DMPC monolayers at different temperatures using epifluorescence surface balance." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ54924.pdf.

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17

Heyer, Elodie. "Elaboration d'édifices multi-chromophoriques à base de DPPs et BODIPYs : vers des applications photovoltaïques." Thesis, Strasbourg, 2014. http://www.theses.fr/2014STRAF022/document.

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Les travaux réalisés au cours de cette thèse ont consisté en l’élaboration d’édifices multi-chromophoriques pour des applications en cellules solaires organiques. La conception de ces nouveaux matériaux a été guidée par trois paramètres : (i) l’augmentation de la planéité pour une meilleure organisation intermoléculaire ; (ii) la modulation de la fenêtre spectrale d’absorption pour capter un maximum de photons ; (iii) l’enrichissement électronique des matériaux pour faciliter la séparation des charges. Notre choix s’est porté sur les hydrocarbures aromatiques polycycliques, de part leurs propr
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18

Pires, Marina Aparecida. "Caracterização das monocamadas mistas (DPPC+BCD) de Langmuir: efeito da estrutura e concentração do BCD e da força iônica na subfase." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/59/59135/tde-22072010-113112/.

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Neste trabalho foram estudadas as interações entre os corantes ciânicos com dois cromóforos (BCD) e monocamadas de Langmuir de fosfolipídio (DPPC). Devido ao alto coeficiente de absorção molar da luz na região ? > 600 nm, ao alto rendimento quântico do estado tripleto, à alta fotocitotoxicidade e à alta afinidade com estruturas celulares os BCD são promissores para serem utilizados em terapia fotodinâmica. Os estudos das características da interação de BCD com a monocamada são importantes tanto para esclarecer os efeitos estruturais na interação de monocamadas com outras moléculas quan
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19

ESSAMPALLY, SURESH. "STUDYING THE INTERACTION OF ANTIFREEZE PROTEINS (TYPE I AND TYPE III) WITH THE PHOSPHOLIPID MONOLAYERS AT AIR/WATER INTERFACE." Cleveland State University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=csu1197407755.

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20

Resca, Elisa <1981&gt. "Stem cells from alternative source in tissue engineering: DPSC osteogenic differentiation on 2D and 3D scaffolds." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2011. http://amsdottorato.unibo.it/3245/.

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21

Al-Arag, Siham. "Les cellules souches de la pulpe dentaire (DPSC) comme vecteurs thérapeutiques pour le traitement du cancer." Thesis, Montpellier, 2020. http://www.theses.fr/2020MONTT044.

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Mon projet de thèse est consacré à l'application clinique potentielle des cellules souches dentaires utilisées comme transporteurs des drogues anticancéreuses pour cibler les cancers, en particulier les cancers oraux. Cela vise à réduire les effets secondaires et à améliorer l'efficacité du traitement systémique de chimiothérapie. La recherche en oncologie et les traitements innovants tels que la thérapie innovante à base de cellules souches sont appliqués dans le domaine pour améliorer la santé générale et la qualité de vie des patients atteints de cancer. Ainsi, le couplage des capacités d'i
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22

Lu, Jun. "A study of lung surfactant (BLES) and dipalmitoyl phosphatidylcholine (DPPC) films using axisymmetric drop shape analysis (ADSA)." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0007/MQ46078.pdf.

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23

Kamran, Beenish, Kate Beatty, LeighAnne Hurst, and Deborah L. Slawson. "Identifying Motivators and Barriers for Wellness Programs to Inform Recruitment and Retention of Diabetes Prevention Programs (DPPs)." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/asrf/2018/schedule/62.

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Obesity and type 2 diabetes (T2DM) has increased greatly in incidence in the United States over the past decade. Diagnosis of T2DM is typically preceded by insulin resistance, which is typically indicated by increases in fasting blood sugar and called pre-diabetes. The Diabetes Prevention Program (DPP) is a group-based program focused on improving diet and maintaining consistent exercise towards a lower body weight. It has been found that minimum weight loss and 150 minutes of moderate exercise is more effective at preventing T2DM than medication-based treatment. Therefore, the DPP has potenti
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Ergun, Seza. "Structural And Functional Investigation Of The Interaction Of Agomelatine With Model Membranes." Master's thesis, METU, 2012. http://etd.lib.metu.edu.tr/upload/12614997/index.pdf.

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Depression is one of the most commonly seen psychiatric diseases in the population in recent years. Treatment of depression is mainly carried out by psychiatric drugs. In the past few years, agomelatine which is released to the market with a trade name, Valdoxane, has been thought to have far less side effects due to its non-addictive nature, not having trouble when the drug is quitted, and also due to its property of binding only to the specific receptor that the drug interacts with. The action mechanism of agomelatine on the membrane structure has not been clarified yet, for instance, no stu
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Maivaldová, Iva. "Interakce fosfolipidů s polyelektrolyty ve vodném prostředí." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2010. http://www.nusl.cz/ntk/nusl-216675.

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This diploma thesis is focused on determination of aggregation behavior of selected phospholipids (lecithin; 1,2-dipalmitoyl-sn-glycerol-3-phosphocholine) in water and on the effect of native hyaluronan addition of various molecular weights and concentrations on this behavior. The behavior has been investigated with fluorescence spectroscopy using pyrene and perylene as fluorescence probes being able to penetrate into hydrophobic cavities of formed aggregates. Critical aggregation concentration and the concentration at which lecithin begins to aggregate have been determined. Regarding 1,2-dipa
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Barboříková, Hana. "Směsné lipidy a jejich interakce s biopolymery." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2017. http://www.nusl.cz/ntk/nusl-316157.

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This thesis focuses on the study of interactions between hyaluronan and lipid DOTAP and its mixtures with DPPC in water. First, the aggregation behavior of the lipid itself and its mixtures was measured, afterwards the influence of hyaluronan in different concentration was studied. Further the fluorescence anisotropy of fluorescence probe DPH in these mixtures and influence of cholesterol was measured. These properties were investigated by fluorescence spectoscopy using pyrene and DPH as fluorescence probes. The measurements revealed that the addition of hyaluronan has observable influence on
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Telesford, Dana-Marie Leslie-Ann. "Langmuir Trough and Brewster Angle Microscopy Study of Model Lung Surfactant Monolayers at the Air/Aqueous Interface." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1353516892.

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28

Budweiser, Johannes [Verfasser], and Lars [Akademischer Betreuer] Lindner. "Hydrolyseverhalten der synthetischen Phospholipide DPPGx (x=1,2,3) im Vergleich zu DPPC in thermosensitiven Liposomen / Johannes Budweiser. Betreuer: Lars Lindner." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2015. http://d-nb.info/1081899786/34.

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Budweiser, Johannes Verfasser], and Lars [Akademischer Betreuer] [Lindner. "Hydrolyseverhalten der synthetischen Phospholipide DPPGx (x=1,2,3) im Vergleich zu DPPC in thermosensitiven Liposomen / Johannes Budweiser. Betreuer: Lars Lindner." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2015. http://d-nb.info/1081899786/34.

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Faria, Amanda Natalina de. "Avaliação da atividade osteogênica de superfícies de titânio revestidas com camadas de lipídios e fosfato de cálcio." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/17/17131/tde-07062017-130153/.

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As coberturas de hidroxiapatita (HAp) são utilizadas para aumentar a osteointegração em implantes de titânio (Ti), devido à sua capacidade de promover a biomineralização para corrigir defeitos esqueléticos e craniofaciais. O objetivo desta pesquisa foi avaliar a influência dos revestimentos sobre culturas primárias de osteoblastos. Na primeira fase de estudos, desenvolvemos uma nova abordagem de revestimento baseada em filmes Langmuir-Blodgett (LB) de dihexadecilfosfato (DHP) e ácido octadecilfosfônico (OPA) depositados em discos Ti, e crescimento subsequente de cristais de HAp. Analisamos a v
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Hamed, Rania Ahmad Azzam. "Development of a physiologically-relevant in vitro system to study exhaled bioaerosols." Diss., University of Iowa, 2011. https://ir.uiowa.edu/etd/4851.

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Airborne infectious diseases remain a major global health threat. The primary vector for their transmission is coarse and fine droplets, known as bioaerosols, exhaled from infected individuals during natural respiratory maneuvers, such as breathing, coughing and sneezing. Unfortunately, our current knowledge of the mechanisms by which these exhaled bioaerosols are formed in the lungs is in its infancy. In particular, progress in this field has been hindered by the complex structure of the respiratory fluid and the resultin
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Lexelius, Rebecka. "Formation of biological membranes." Thesis, Uppsala universitet, Molekyl- och kondenserade materiens fysik, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-415899.

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The amphiphilic property of phospholipids drives the spontaneous formation of various molecular aggregates in response to their surrounding environment. In this study the concentration of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) lipids in water was varied in order to investigate the naturally occurring arrangements over time, and specifically the propensity to form monolayers on the water-vacuum interface. Several forms of aggregates developed during the 1000 ns long simulations, including monolayers and spherical- as well as cylindrical micelles. In all simulations the majority of l
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Fuentes, Barahona Pablo César. "Desactivación del O2(a¹Δg) por licopeno y por los ácidos rosmarínico y carnósico en liposomas de dodac y de DPPC". Tesis, Universidad de Chile, 2014. http://repositorio.uchile.cl/handle/2250/145792.

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Memoria para optar al Título Profesional de Químico y al Grado de Magíster en Química, área de especialización en coloides<br>El metabolismo celular es un proceso natural en los organismos vivos que conduce inevitablemente a la producción de especies reactivas del oxígeno, conocidas como ROS, las cuales, son agentes oxidantes altamente reactivos capaces de atacar células, causando en ellas la pérdida de su estructura y funciones. El exceso de ROS en el organismo, un estado que se conoce como “estrés oxidativo”, es mantenido bajo control por mecanismos celulares y especies antioxidantes, e
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Zbořilová, Hana. "Studium membránových vlastností liposomálních systémů pomocí fluorescenční spektroskopie." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2021. http://www.nusl.cz/ntk/nusl-449373.

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The presented diploma thesis is focused on the preparation, characterization and study of membrane properties of liposomal systems which were composed of the neutral phosphatidylcholine (DPPC), cholesterol, negatively charged phosphatidylglycerol (DPPG), polyethylenglycol bounded to phosphatidylethanolamine (PEG5000–PE) and polycation N,N,N-trimethylchitosan (TMC). The influence of individual components and their concentrations on the average particle size, zeta potential and changes in the outer and inner part of the bilayer was investigated. In this matter, methods of dynamic and electrophor
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Kocak, Mustafa. "Interactions Of Cholesterol Reducing Agent Simvastatin With Phospholipid Model Membranes." Master's thesis, METU, 2007. http://etd.lib.metu.edu.tr/upload/12608220/index.pdf.

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Interactions of simvastatin with zwitterionic dipalmitoyl phosphotidylcholine (DPPC) multilamellar liposomes were investigated as a function of temperature and simvastatin concentration. And acyl chain length effect on the simvastatin-model membrane interactions was monitored with DPPC and dimyristoyl phosphotidylcholine (DMPC) lipids. All studies were carried out by two non-invasive techniques, namely Fourier transform infrared (FTIR) spectroscopy, and differential scanning calorimetry (DSC). The results showed that as simvastatin concentration increased, the main phase transition temperatur
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Casillas-Ituarte, Nadia Ninel. "Spectroscopic Studies of Atmospheric Relevant Air-Aqueous and Air-Silica Interfaces." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1268155570.

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Bruck, Angela Lynette. "Friction and wear behavior of ultra-high molecular weight polyethylene as a function of crystallinity and in the presence of the phospholipid DPPC (dipalmitoyl phosphatidylcholine)." [Ames, Iowa : Iowa State University], 2007.

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Li, Sixuan. "Synovial fluid components as synergistic lubricants in articular joint models." Thesis, KTH, Kemi, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-266374.

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The excellent lubrication present within mammalian synovial joints attracted scientific interest, and some close-to-realistic models were applied to study the mechanism in vitro. In this project, the synergistic lubrication of synovial fluid was investigated by using 1,2-Dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC), hyaluronic acid (HA), and phosphate-buffered saline (PBS buffer) to mimic the synovial fluid. Lubrication by the model synovial fluid was studied using borosilicate glass specimens in Mini-Traction Machine (MTM). The experiments proved that the DPPC vesicle solution and mixe
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Castada, Hardy Zingalaoa. "Brewster Angle Microscopy Study of Model Lung Surfactant Systems at the Air-Water and Air-Physiological Buffer Interfaces." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1281642097.

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Hauet, Nathalie. "Caractérisation des interactions membranes modéles-Enflurane, un anesthésique général, fluoré et volatil." Paris 6, 2002. http://www.theses.fr/2002PA066176.

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Raj, Akanksha. "Synergies in Biolubrication." Doctoral thesis, KTH, Yt- och korrosionsvetenskap, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-201219.

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The objective of this thesis was to advance understanding in the field of biolubrication, finding inspiration from the human synovial joints. This was addressed by investigating the association of key biolubricants and the resulting lubrication performance. Techniques employed during the course of this work were Atomic force microscopy (AFM), Quartz crystal microbalance with dissipation monitoring (QCM-D), X-ray reflectivity (XRR). Key synovial fluid and cartilage components like dipalmitoylphosphatidylcholine (DPPC), hyaluronan (HA), lubricin, and cartilage oligomeric matrix protein (COMP) ha
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Bauer, Michel. "Etude par analyse enthalpique différentielle de l'interaction de drogues inhibitrices de l'activité de la phospholipase A et de drogues antidépressives avec le liposome DPPC pris comme modèle de la membrane biologique." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb37602646t.

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Lexelius, Rebecka. "Formation of Monolayered Phospholipids using Molecular Dynamics." Thesis, Uppsala universitet, Molekyl- och kondenserade materiens fysik, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-356370.

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The very fundamental properties of biological membranes can be understood by studying their formation. This sets a good foundation for research related to how the membranes interact with organic molecules and ions; something of great value in the quest of explaining transport phenomena through cell membranes. It is furthermore of growing interest within the pharmacological research and contributes to the apprehension of life at the molecular level. In this thesis Molecular Dynamics has been used to simulate how evenly distributed phospholipids solvated in water leads to the formation of monola
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Ponsot, Flavien. "Hybrides bactériochlorine-dicétopyrrolopyrrole (DPP) : Nouveaux fluorophores proche infrarouge pour des applications en biodétection/bioimagerie." Thesis, Bourgogne Franche-Comté, 2020. https://nuxeo.u-bourgogne.fr/nuxeo/site/esupversions/1fa27cab-663e-4192-be47-cd34a712a1cd.

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Les fluorophores organiques absorbant et émettant dans le proche infrarouge (700-900 nm, première fenêtre thérapeutique NIR-I) sont des outils de choix pour une application en bioimagerie. En effet, l'absorption, la diffusion et l'autofluorescence de constituants du milieu biologiques sont limitées dans cette région spectrale, rendant les tissus relativement transparents à ces longueurs d'onde. Les bactériochlorines sont des dérivés de porphyrines dont deux doubles liaisons sont réduites. Ces molécules présentent une forte absorption et une émission dans le NIR-I. Les DPP sont des fluorophores
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Faye, Djibril. "Détection fluorimétrique en circuit microfluidique des ions Pb2+, Hg2+ et Cd2+ en milieu aqueux." Phd thesis, École normale supérieure de Cachan - ENS Cachan, 2011. http://tel.archives-ouvertes.fr/tel-00722906.

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Ce travail de thèse s'inscrit dans le cas d'un projet européen nommé " microfluiD ". Ce projet vise principalement la détection des polluants organiques par voie microfluidique (les micotoxines dans les aliments de bétail, les bactéries et les métaux lourds). Devant les dangers écologiques des ions Pb2+, Hg2+ et Cd2+ dans l'environnement, il est important de multiplier le nombre d'analyses dans les eaux du robinet. L'utilisation de la fluorescence et des microlasers organiques présente de nombreux avantages. Outre leur faible coût, leur sensibilité ainsi que leur sélectivité, il est possible d
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Chou, Tzung-Han, and 周宗翰. "Molecular Interactions of Mixed Monolayers Containing DPPC." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/70618641096228772150.

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碩士<br>國立成功大學<br>化學工程學系<br>87<br>This study investigated the behavior of mixed DPPC/cholesterol monolayers and mixed DPPC/DHDP monolayers at the air/liquid interface at 37 . For DPPC/cholesterol mixed system at the air/water interface, the measurements of surface pressure-area per molecule (P-A) isotherms and relaxation curves were carried out. In the thermodynamic analysis of the mixed monolayers, the areas of monolayers exhibited negative deviations from the ideal values at all compositions for lower surface pressures. However, at higher surface pressures, distinctively positive deviations
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余信德. "Interfacial Properties of Mixed DPPC/Protein Monolayers." Thesis, 1997. http://ndltd.ncl.edu.tw/handle/35140218342427995646.

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碩士<br>國立成功大學<br>化學工程研究所<br>85<br>The hysteresis behavior of air/protein solution interface with or without DPPC monolayer is studied. The air/protein solution interface shows reproducible hysteresis behavior, which implies that both γ-globulin and lysozyme molecules have good respreading ability, and also indicates the characteristics of the slow desorption and fast readsorption behavior of proteins. As tile DPPC monolayer is spread on the air/protein solution interface, the surface pressure jumps immediately and slowly decreases to reach an equilibrium value. The typical collapse behavior
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Tom-Kun, Yamagishi Valerie. "Blockade of TLR2 Inhibits P. gingivalis Suppression of Mineralized Matrix Formation by Human Dental Pulp Stem Cells." Thesis, 2011. http://hdl.handle.net/1807/31618.

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In an effort to re-establish tissue with odontogenic potential in the pulp space of immature permanent teeth, stimulated human dental pulp stem/progenitor cells (hDPSCs) have shown potential to differentiate and form mineralized matrix, marked by high expression of dentin sialophosphoprotein (DSPP) and osteocalcin (OCN). Bacterial by-products have been shown to adversely affect cell differentiation. This study investigated the effect of P. gingivalis, a putative endodontic pathogen, and blockage of its host recognition on hDPSCs. Stimulated hDPSCs were exposed to varying concentrations of P. g
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Chen, Yan-shi, and 陳衍錫. "The effect of sterol on the POPE/DPPC membranes." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/3dytbq.

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碩士<br>國立中央大學<br>生物物理研究所<br>101<br>The specialized membrane microdomain was found in the mammalian cells membrane which termed lipid rafts with different physical and chemical properties. The lipid rafts contain 3 to 5-fold the amount of cholesterol found in the surrounding bilayer. Like cholesterol in mammalian cell membrane, ergosterol is important to the raft in the yeast cell membrane. To gain a better understanding of the effect of sterols on biological membrane properties requires investigations of the phase behavior. We study the physical properties of model membranes for binary mixture
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Wang, Hong-Yu, and 王宏榆. "Microstructure of Mixed DPPC/PA Monolayer Observed by AFM." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/34984169513918620131.

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碩士<br>國立宜蘭大學<br>生物機電工程學系碩士班<br>104<br>The objective of this research is to study the stability of DPPC/PA monolayers at air-water interface. DPPC and PA are the main compositions of human pulmonary surfactants that contribute to the surface tension-lowering ability of pulmonary surfactants. Previous studies indicated that DPPC alone cannot substitute natural pulmonary surfactant to restore the normal function of a lung because the DPPC monolayer is unstable over its dynamic compression–expansion cycle. A LB film balance system was utilized to monitor the dynamic surface pressure-area iso
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