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1

Humphries, P. A. "Excrescence effects on a turbulent boundary layer in an adverse pressure gradient." Thesis, Queen's University Belfast, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368571.

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2

Dominguez, Ontiveros Elvis Efren. "Wall-pressure and PIV analysis for microbubble drag reduction investigation." Texas A&M University, 2004. http://hdl.handle.net/1969.1/2582.

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The effects of microbubbles injection in the boundary layer of a turbulent channel flow are investigated. Electrolysis demonstrated to be an effective method to produce microbubbles with an average diameter of 30 ??m and allowed the placement of microbubbles at desired locations within the boundary layer. Measurement of velocity fluctuations and the instantaneous wall shear stress were carried out in a channel flow facility. The wall shear stress is an important parameter that can help with the characterization of the boundary layer. This parameter can be obtained indirectly by the measurement of the flow pressure at the wall. The wall shear stress in the channel was measured by means of three different independent methods: measurement of the pressure gradient by a differential pressure transducer, Particle Image Velocimetry (PIV), and an optical wall shear stress sensor. The three methods showed reasonable agreement of the wall shear stress values for single-phase flow. However, differences as skin friction reductions were observed when the microbubbles were injected. Several measurements of wall-pressure were taken at various Reynolds numbers that ranged from 300 up to 6154. No significant drag reduction was observed for flows in the laminar range; however, a drag reduction of about 16% was detected for turbulent Reynolds numbers. The wall-pressure measurements were shown to be a powerful tool for the measurement of drag reduction, which could help with the design of systems capable of controlling the skin friction based on feedback given by the wall-pressure signal. The proposed measurement system designed in this work has capabilities for application in such diverse fields as multiphase flows, drag reduction, stratified flows, heat transfer among others. The synchronization between independent systems and apparatus has the potential to bring insight about the complicated phenomena involved in the nature of fluid flows.
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3

Ercan, Can. "Phpa As A Frictional Pressure Loss Reducer And Its Pressure Loss Estimation." Master's thesis, METU, 2007. http://etd.lib.metu.edu.tr/upload/12608451/index.pdf.

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As the demand of oil and gas is increasing, using the existing reservoirs more efficiently as well as searching for new reservoirs is mandatory. Most undiscovered reservoirs are in deep or ultra-deep offshore locations, where drilling to such targets are very difficult with the available fluid circulation technology, since there exists a significant frictional pressure loss due to extreme long wellbores. In order to reduce the frictional pressure losses inside the drillstring, frictional drag reducers are used. Frictional drag reducers are mostly high molecular weight linear polymer molecules and can be used with water or hydrocarbon based solvents. The system used in this study is Baroid EZ-Mud water solutions. Baroid EZ-Mud is a liquid polymer emulsion containing partially hydrolyzed polyacrylamide / polyacrylate (PHPA) co-polymer. This study aims to observe the performance of EZ-Mud as a frictional drag reducer. For this purpose, a flow loop that consisted of a circular pipe where the frictional pressure losses can be observed under various flow rates and concentrations is developed. Pipe flow experiments were performed using water-based mud generated using different concentrations of Baroid EZ-Mud at different flow rates. Differential pressure values were recorded for each run. Rheological properties of each mud sample were determined using Fann (Couette) viscometer in order to determine the theoretical frictional pressure losses. Theoretical and measured frictional pressure losses were compared. Results showed that, as the concentration of EZ-Mud was increased, considerable frictional drag reduction as high as 60% was observed. Based on the experimental data obtained from the flow loop using EZ-Mud with different concentrations, a friction factor correlation as a function of Reynolds Number and EZ-Mud concentration is developed. The proposed correlation performance was also compared with the existing correlations from the literature. It has been observed that, frictional pressure losses using the developed friction factor could be estimated within an error range of maximum 15 %, whereas, the existing models could not predict frictional pressure losses as accurate as the proposed model.
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4

Priyono, Eddy. "An investigation of the transonic pressure drag coefficient for axi-symmetric bodies." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 1994. http://handle.dtic.mil/100.2/ADA280990.

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5

Vancko, Robert M. "Effect of a drag reducing agent on pressure drop and flow regime transitions in multiphase horizontal low pressure pipelines." Ohio : Ohio University, 1997. http://www.ohiolink.edu/etd/view.cgi?ohiou1184354301.

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6

Vancko, Jr Robert M. "Effect of a drag reducing agent on pressure drop and flow regime transitions in multiphase horizontal low pressure pipelines." Ohio University / OhioLINK, 1997. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1184354301.

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7

Daas, Mutaz A. "Effects of drag reducing agents on pressure drop and flow characteristics in multiphase inclined pipelines." Ohio : Ohio University, 2000. http://www.ohiolink.edu/etd/view.cgi?ohiou1171651331.

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8

Dominic, Justin. "Experimental Study of Wall Shear Stress Modification by Surface Coating: Pressure Drop Measurements in a Rectangular Channel." Thesis, Virginia Tech, 2011. http://hdl.handle.net/10919/76796.

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Presented in this paper are experiments to test the hypothesis that drag reduction is possible over hydrophobic surfaces in the Wenzel state during laminar and turbulent flows. Quantification of surface drag reduction in rectangular channel flow over walls with specific hydrophobic or hydrophilic properties was obtained with pressure drop measurements along the channel for a range of Reynolds numbers between 350 and 5900. Several commercially available materials and coatings were chosen in order to span a range of contact angles between 30° and 135°. The results are within the bounds of the theoretical values calculated with the Colebrook equation, and do not show any reduction in wall shear stress as a function of material properties or surface chemistry. The differences between this experiment and others measuring pressure drop over hydrophobic surfaces is the macro-scale conditions and the hydrophobic surfaces being fully wetted. These experiments are further proof of the importance of a liquid-vapor interface for increasing the shear free area to produce drag reduction.<br>Master of Science
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9

Thrift, Alan Albright. "Aerodynamic Force and Pressure Loss Measurements on Low Aspect Ratio Pin Fin Arrays." Thesis, Virginia Tech, 2007. http://hdl.handle.net/10919/31189.

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The desire to achieve higher heat transfer augmentation for turbine blades is fueled by the increased power output and efficiency that is achievable with high turbine inlet temperatures. The use of internal cooling channels fitted with pin fin arrays serves as one method of accomplishing this goal. Consequently, the addition of pin fin arrays comes at the expense of increased pressure drop. Therefore the pin fin geometry must be judiciously chosen to achieve the required heat transfer rate while minimizing the associated pressure drop. <p> This project culminates in the measurement of both pin fin force and array pressure drop as they related to changes in the array geometry. Specifically, the effects of Reynolds number, spanwise pin spacing, streamwise pin spacing, pin aspect ratio, and flow incidence angle. Direct two-component force measurement is achieved with a cantilever beam force sensor that uses highly sensitive piezoresistive strain gauges, relating the strain at the base of the beam to the applied force. With proper characterization, forces as small as one-tenth the weight of a paper clip are successfully measured. Additionally, array pressure drop measurements are achieved using static pressure taps. <p> Experiments were conducted over a range of Reynolds numbers between 7,500 and 35,000. Changes in the spanwise pin spacing were shown to substantially alter the pin fin drag and array pressure drop, while changes in the streamwise pin spacing were less influential. The experimental results also showed a dramatic reduction in the pin fin drag and array pressure drop for an inline flow incidence angle. Finally, changes in the pin aspect ratio were shown to have little effect on the array pressure drop.<br>Master of Science
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10

Stucki, Chad Lamar. "Aerodynamic Design Optimization of a Locomotive Nose Fairing for Reducing Drag." BYU ScholarsArchive, 2019. https://scholarsarchive.byu.edu/etd/7478.

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Rising fuel cost has motivated increased fuel efficiency for freight trains. At cruising speed,the largest contributing factor to the fuel consumption is aerodynamic drag. As a result of stagnationand flow separation on and around lead and trailing cars, the first and last railcars experiencegreater drag than intermediate cars. Accordingly, this work focused on reducing drag on lead locomotivesby designing and optimizing an add-on nose fairing that is feasible for industrial operation.The fairing shape design was performed via computational fluid dynamic (CFD) software.The simulations consisted of two in-line freight locomotives, a stretch of rails on a raised subgrade,a computational domain, and a unique fairing geometry that was attached to the lead locomotive ineach non-baseline case. Relative motion was simulated by fixing the train and translating the rails,subgrade, and ground at a constant velocity. An equivalent uniform inlet velocity was applied atzero degree yaw to simulate relative motion between the air and the train.Five fairing families-Fairing Families A-E (FFA-FFE)-are presented in this thesis.Multidimensional regressions are created for each family to approximate drag as a function ofthe design variables. Thus, railroad companies may choose an alternative fairing if the recommendedfairing does not meet their needs and still have a performance estimate. The regression forFFE is used as a surrogate model in a surrogate based optimization. Results from a wind tunneltest and from CFD are reported on an FFE geometry to validate the CFD model. The wind tunneltest predicts a nominal drag reduction of 16%, and the CFD model predicts a reduction of 17%.A qualitative analysis is performed on the simulations containing the baseline locomotive, the optimalfairings from FFA-FFC, and the hybrid child and parent geometries from FFA & FFC. Theanalysis reveals that optimal performance is achieved for a narrow geometry from FFC becausesuction behind the fairing is greatly reduced. Similarly, the analysis reveals that concave geometriesboost the flow over the top leading edge of the locomotive, thus eliminating a vortex upstreamof the windshields. As a result, concave geometries yield greater reductions in drag.The design variable definitions for each family were strategically selected to improve manufacturability,operational safety, and aerodynamic performance relative to the previous families.As a result, the optimal geometry from FFE is believed to most completely satisfy the constraintsof the design problem and should be given the most consideration for application in the railroadindustry. The CFD solution for this particular geometry suggests a nominal drag reduction of 17%on the lead locomotive in an industrial freight train.
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11

Lacis, Ugis. "Nature-inspired passive flow control using various coatings and appendages." Licentiate thesis, KTH, Stabilitet, Transition, Kontroll, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-158319.

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There is a wide variety of tails, fins, scales, riblets and surface coatings, which are used by motile animals in nature. Since organisms currently living on earth have gone through millions of years of evolution, one can expect that their design is optimal for their tasks, including locomotion. However, the exterior of living animals has range of different functions, from camouflage to heat insulation; therefore it is a very challenging task to isolate mechanisms, which are beneficial to reduce the motion resistance of the body. There are two general categories of mechanisms existing in locomotion and flow control. The first is active flow control, when an organism is actively moving some parts or the whole body (exerts energy) in order to modify the surrounding flow field (for example, flapping bird wings). The second is passive flow control, in which an organism has an appendage or a coating, which is not actively controlled (no energy is spent), but is interacting with surrounding flow in a beneficial way. Our aim is to find novel mechanisms for passive flow control. We start by looking at a simple model of an appendage (splitter plate) behind a bluff body (circular cylinder). If a recirculation region forms behind the body, already in this simple system there is a symmetry breaking effect for sufficiently short plates, which passively generates turn and drift of the body. We have found that this effect is caused by the pressure forces in the recirculation region, which pushes the plate away from the vertical in a manner similar to how a straight inverted pendulum falls under the influence of gravity. In order to investigate this symmetry breaking, we developed an extension of the immersed boundary projection method, in which the rigid body dynamics and fluid dynamics are coupled implicitly. The method is capable of solving for particle motion in a fluid for very small density ratios. We also explain our findings by a simple yet quantitative reduced-order model and soap-film experiments. To extend our work, we investigate flow around bodies, which are coated by a porous and elastic material. We have analysed various theoretical approaches to modeling a coating in a continuous manner. We aim to solve the governing equations numerically. We have selected multi-scale expansion approach, of which we present some initial results.<br>Många djur använder sig av fjäll, päls, hår eller fjädrar för att öka sin förmåga att förflytta sig i luft eller vatten. Evolutionen har främjat ojämna, sträva eller gropiga ytor, vilka har en tendens att minska det totala motståndet som uppstår när en kropp rör sig i vatten eller luft, jämfört med en helt slät och jämn yta.Det finns två kategorier av metoder för manipulering av strömning (så kallad flödeskontroll). Den första är en aktiv metod, där organismer aktivt rör hela eller delar av kroppen (förbrukar energi) för att manipulera omgivande strömningsfält. Den andra metoden är passiv, där organismer har utväxter eller ytbeläggningar som de inte är aktivt har kontroll över (ingen energi förbrukas), men som samverkar med omgivande strömningsfält på ett fördelaktigt sätt. Vårt mål är att hitta nya mekanismer för passiv flödeskontroll.Vi börjar med att studera en enkel modell för hur en utväxt samverkar med en strömmande fluid genom att fästa en platta på en cirkulär cylinder. Om en vak (så-kallad återcirkulationsregion) bildas bakom kroppen, bryts symmetrin i strömningsfältet då plattan är tillräckligt kort. Som en konsekvens av detta roterar kroppen och driver i sidled. Vi visar att detta fenomen orsakas av tryckkrafter i återcirkulationsregionen, som förskjuter plattan från dess vertikala läge. Vi argumenterar att denna mekanism är samma mekanism som får en inverterad pendel att falla under inverkan av gravitation. För att analysera symmetribrytningen, utvecklade vi en numerisk metod (immersed boundary projection method), som implicit kopplar stelkropps- och strömningsdynamik. Med hjälp av denna metod kan vi simulera partiklar i fluider med väldigt låga densitetsskillnader. Våra resultat förklaras även med hjälp av en enkel modell av låg ordning och med hjälp av såphinneexperiment.Som nästa steg i vårt arbete, ämnar vi att studera strömningen kring kroppar som är belagda av tät, porös och elastisk beläggning. Vi har analyserat möjliga tillvägagångssätt för att modellera beläggningar med kontinuumteori. Vi har valt en metod baserad på en flerskalig expansionsmetod, från vilken vi presenterar våra preliminära resultat.<br><p>QC 20150119</p>
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12

Rabe, Richard L. "Drag and pressure die flow effects on the production and properties of a Rayon-Nylon skin-core type composite fiber." Ohio University / OhioLINK, 1987. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1183057790.

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13

Brumbaugh, Scott J. "Development of a Methodology to Measure Aerodynamic Forces on Pin Fins in Channel Flow." Thesis, Virginia Tech, 2006. http://hdl.handle.net/10919/30871.

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The desire for smaller, faster, and more efficient products places a strain on thermal management in components ranging from gas turbine blades to computers. Heat exchangers that utilize internal cooling flows have shown promise in both of these industries. Although pin fins are often placed in the cooling channels to augment heat transfer, their addition comes at the expense of increased pressure drop. Consequently, the pin fin geometry must be judiciously chosen to achieve the desired heat transfer rate while minimizing the pressure drop and accompanying pumping requirements. This project culminates in the construction of a new test facility and the development of a unique force measurement methodology. Direct force measurement is achieved with a cantilever beam force sensor that uses sensitive piezoresistive strain gauges to simultaneously measure aerodynamic lift and drag forces on a pin fin. After eliminating the detrimental environmental influences, forces as small as one-tenth the weight of a paper clip are successfully measured. Although the drag of an infinitely long cylinder in uniform cross flow is well documented, the literature does not discuss the aerodynamic forces on a cylinder with an aspect ratio of unity in channel flow. Measured results indicate that the drag coefficient of a cylindrical pin in a single row array is greater than the drag coefficient of an infinite cylinder in cross flow. This phenomenon is believed to be caused by an augmentation of viscous drag on the pin fin induced by the increased viscous effects inherent in channel flow.<br>Master of Science
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14

Józsa, Tamás István. "Drag reduction by passive in-plane wall motions in turbulent wall-bounded flows." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/33155.

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Losses associated with turbulent flows dissipate a significant amount of generated energy. Such losses originate from the drag force, which is often described as the sum of the pressure drag and the friction drag. This thesis sets out to explore the hypothesis that passive wall motions driven by fluid mechanical forces are able to reduce the friction drag in fully developed turbulent boundary layers. Firstly, the streamwise and spanwise opposition controls proposed by Choi et al. (1994, Journal of Fluid Mechanics) are revisited to identify beneficial wall motions. Near-wall streamwise or spanwise velocity fluctuations are measured along a detection plane parallel to the wall (sensing). For streamwise control, the wall velocities are set to be equivalent to the measured streamwise velocity fluctuations, whereas for spanwise control, the wall velocities are set to have the same magnitude but opposite direction as the measured spanwise velocity fluctuations (actuation). Direct numerical simulations of canonical turbulent channel flows are carried out at low (Reτ ≈ 180) and intermediate (Reτ ≈ 1000) Reynolds numbers to quantify the effect of the distance between the wall and the detection plane. The investigation reveals the primary differences between the mechanisms underlying the two active in-plane controls. The modified flow features and turbulence statistics show that the streamwise control amplifies the most energetic streamwise velocity fluctuations and damps the near-wall vorticity fluctuations. In comparison, the spanwise control induces near-wall vorticity in order to counteract the quasi-streamwise vortices of the near-wall cycle and suppress turbulence production. Although, the working principles of the active controls are fundamentally different, both achieve drag reduction by mitigating momentum transfer between the velocity components. Secondly, two theoretical passive compliant wall models are proposed, the aim being to sustain beneficial wall motions identified by active flow control simulations. In the proposed models, streamwise or spanwise in-plane wall motions are governed by an array of independent one-degree-of-freedom damped harmonic oscillators. Unidirectional wall motions are driven by local streamwise or spanwise wall shear stresses. A weak coupling scheme is implemented to investigate the interaction between the compliant surface models and the turbulent flow in the channel by means of direct numerical simulations. A linear analytical solution of the coupled differential equation system is derived for laminar pulsatile channel flows allowing verification and validation of the numerical model. The obtained analytical solution is utilised to map the parameter space of the passive controls and estimate the effect of the wall motions. It is shown that depending on the control parameters, the proposed compliant walls decrease or increase the vorticity fluctuations at the wall similarly to the active controls. This is confirmed by direct numerical simulations. On the one hand, when the control parameters are chosen appropriately, the passive streamwise control damps the near-wall vorticity fluctuations and sustains the same drag reduction mechanism as the active streamwise control. This leads to modest, 3.7% and 2.3% drag reductions at low and intermediate Reynolds numbers. On the other hand, the spanwise passive control is not capable of increasing the near-wall vorticity fluctuations as dictated by the active spanwise control. For this reason, passive spanwise wall motions can increase the friction drag by more than 50%. The results emphasise the necessity of anisotropy for a practical compliant wall design. The present work demonstrates for the first time that passive wall motions can decrease friction drag in fully turbulent wall-bounded flows. The thesis sheds light on the working principle of an active streamwise control, and proposes a passive streamwise control exploiting the same drag reduction mechanism. An analytical model is developed to give a ready prediction of the statistical behaviour of passive in-plane wall motions. Whereas streamwise passive wall motions are found beneficial when the control parameters are chosen appropriately, solely spanwise passive wall motions lead to a drag penalty.
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15

Rauthan, Kanishk. "Investigation of surface textures on thermal and pressure drop performance of plate-fin heat exchangers." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2022. https://ro.ecu.edu.au/theses/2597.

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Firstly, I would like to show my sincere gratitude to my supervisors Dr. Ferdinando Guzzomi and Dr. Ana Vafadar for their immeasurable guidance and support throughout the duration of the project. Dr. Guzzomi and Dr. Vafadar have always had an open-door policy for me which helped me accomplish my goals on or before the deadlines. I highly appreciate Dr. Ferdinando Guzzomi for listening to and putting up with my ridiculous ideas and vision towards the project and pointing me in the right course of direction. I would like to thank Dr. Guzzomi for giving me the creative freedom and putting his trust on me with the project, allowing me to think outside the box and making my ideas a reality. I would also like to show my heartfelt appreciation towards Dr. Ana Vafadar for listening to my confusion every week and to draw meaning out of my words. Your feedback along with the constructive criticism has been highly valuable throughout this journey and has kept me in check. Your constant support and faith in me have allowed me to finish the project on time and with significant contributions to the area of my research. Dr. Kevin Hayward has also played a key role in the completion of this project. His feedback and suggestions towards my manuscripts and reports and numerous data analysis techniques have been critical in making this work presentable. From the bottom of my heart, I would like to say a big thank you to Mr. Adrian Davis, Dr. Michael Stein and Joshua Bolton for their technical and literacy support throughout my bachelors and master’s project. Without your guidance and wisdom, none of this would have been possible. A special thanks goes to my fellow researchers Aakash Shaun Hurry and Prashan Perera for all the cake and coffee I’ve had in the past 2 years and for the lovely discussions we had regarding our projects. I highly appreciate their immense support through times of doubt and uncertainty. I would also like to thank the ECU-Motorsports team specially Adam Honeycombe and Mario Leone for allowing me to use the facilities within the motorsports workshop and to be a part of the team and experience the Aus-West competition. I will cherish these memories and friendships forever. Last but not the least, my biggest gratitude goes towards my uncle and aunt for their unconditional love and support throughout my bachelors and masters. I would not be where I am without their constant support. I would also like to thank my family and friends back in India who have helped me through this journey and allowed me to accomplish my goals.
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16

Tullius, Lisa. "A study of drag reducing agents in multiphase flow in large diameter horizontal pipelines." Ohio : Ohio University, 2000. http://www.ohiolink.edu/etd/view.cgi?ohiou1181066439.

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17

Tárnok, Gábor. "Aerodynamická interakce dvou vozidel." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2010. http://www.nusl.cz/ntk/nusl-374732.

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Tárnok, Gábor. "Aerodynamická interakce dvou vozidel." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2011. http://www.nusl.cz/ntk/nusl-229895.

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19

Iyalla, Ibiyekariwaripiribo. "Computational fluid dynamics modelling of pipeline on-bottom stability." Thesis, Robert Gordon University, 2017. http://hdl.handle.net/10059/2721.

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Subsea pipelines are subjected to wave and steady current loads which cause pipeline stability problems. Current knowledge and understanding on the pipeline on-bottom stability is based on the research programmes from the 1980’s such as the Pipeline Stability Design Project (PIPESTAB) and American Gas Association (AGA) in Joint Industry Project. These projects have mainly provided information regarding hydrodynamic loads on pipeline and soil resistance in isolation. In reality, the pipeline stability problem is much more complex involving hydrodynamic loadings, pipeline response, soil resistance, embedment and pipe-soil-fluid interaction. In this thesis Computational Fluid Dynamics (CFD) modelling is used to investigate and establish the interrelationship between fluid (hydrodynamics), pipe (subsea pipeline), and soil (seabed). The effect of soil types, soil resistance, soil porosity and soil unit weight on embedment was examined. The overall pipeline stability alongside pipeline diameter and weight and hydrodynamic effect on both soil (resulting in scouring) and pipeline was also investigated. The use of CFD provided a better understanding of the complex physical processes of fluid-pipe-soil interaction. The results show that the magnitude of passive resistance is on the average eight times that of lateral resistance. Thus passive resistance is of greater significance for subsea pipeline stability design hence the reason why Coulomb’s friction theory is considered as conservative for stability design analysis, as it ignores passive resistance and underestimates lateral resistance. Previous works (such as that carried out by Lyons and DNV) concluded that soil resistance should be determined by considering Coulomb’s friction based on lateral resistance and passive resistance due to pipeline embedment, but the significance of passive resistance in pipeline stability and its variation in sand and clay soils have not be established as shown in this thesis. The results for soil porosity show that increase in pipeline stability with increasing porosity is due to increased soil liquefaction which increases soil resistance. The pipe-soil interaction model by Wagner et al. established the effect of soil porosity on lateral soil resistance but did not attribute it to soil liquefaction. Results showed that the effect of pipeline diameter and weight vary with soil type; for sand, pipeline diameter showed a greater influence on embedment with a 110% increase in embedment (considering combined effect of diameter and weight) and a 65% decrease in embedment when normalised with diameter. While pipeline weight showed a greater influence on embedment in clay with a 410% increase. The work of Gao et al. did not completely establish the combined effect of pipeline diameter and weight and soil type on stability. Results also show that pipeline instability is due to a combination of pipeline displacement due to vortex shedding and scouring effect with increasing velocity. As scoring progresses, maximum embedment is reached at the point of highest velocity. The conclusion of this thesis is that designing for optimum subsea pipeline stability without adopting an overly conservative approach requires taking into consideration the following; combined effect of hydrodynamics of fluid flow on soil type and properties, and the pipeline, and the resultant scour effect leading to pipeline embedment. These results were validated against previous experimental and analytical work of Gao et al, Brennodden et al and Griffiths.
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20

Bonaca, Alessio. "Modellizzazione dell'accelerazione di pressione di radiazione solare di BepiColombo." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2021.

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L’obiettivo di questo progetto è lo sviluppo di algoritmi per il calcolo delle accelerazioni dovute alla pressione di radiazione solare che agisce su uno spacecraft. Il riferimento di questo studio è la missione BepiColombo, realizzata da ESA in collaborazione con JAXA (Agenzia Spaziale Giapponese), avente l’obiettivo di raggiungere il pianeta Mercurio per analizzarlo, utilizzando vari payload scientifici a bordo dei due moduli da cui è formata. Il progetto è concentrato sull’analisi delle forze che si generano sul modulo europeo MPO: data la vicinanza di Mercurio al Sole, la principale perturbazione nella sua orbita è dovuta proprio alla pressione di radiazione solare. La prima fase del progetto consiste nella schematizzazione di modelli geometrici a facce piane dello spacecraft, da utilizzare in seguito per il calcolo delle azioni sul corpo: sono state quindi realizzate geometrie semplificate dei principali componenti della missione e sono stati recuperati modelli più dettagliati di questi, realizzati da ESA. A partire da questi modelli, è stata realizzata una geometria di MPO costituita da un bus e da un pannello solare, includendo anche la possibile rotazione del pannello attorno al suo asse. Successivamente è stato sviluppato un algoritmo che, utilizzando il nuovo modello, permette di calcolare la pressione di radiazione solare risultante, sommando i contributi dovuti a ciascuna faccia piana. Questa stima è stata migliorata introducendo un algoritmo di shadowing, in grado di valutare se alcune facce o parti di esse siano in ombra a causa delle altre componenti. Gli accorgimenti appena descritti sono stati impiegati anche per il calcolo delle azioni sull’antenna ad alto guadagno del modulo di MPO. Infine, sono state realizzate stime della Poynting-Robertson drag, una perturbazione legata alla pressione di radiazione solare e alla velocità di un corpo rispetto alla sorgente di radiazione.
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Castejon, Danilo Vieira. "Métodos de redução do arrasto e seus impactos sobre a estabilidade veicular." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/18/18148/tde-25082011-205657/.

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A crescente preocupação ambiental e a necessidade de se criar produtos mais eficientes têm impulsionado os pesquisadores a realizarem estudos acerca da aerodinâmica veicular. Estes dois fatores constituem os principais motivos, pelos quais existe uma grande procura por conhecimento nesta área. Esta ciência pode ser considerada relativamente nova e ainda carece de uma base de dados. Entender como a aerodinâmica se relaciona com o consumo de combustível nos automóveis, à medida que o arrasto impõe resistência ao deslocamento dos mesmos, é algo que tem estimulado as indústrias automotivas a investirem grandes esforços na obtenção de ferramentas, que possam representar as condições de tráfego normais e, assim conseguir prever o desempenho do produto em desenvolvimento. Os túneis de vento e a simulação computacional surgem neste ambiente como as principais ferramentas de análise e predição do escoamento ao redor do veículo. Por isso seu entendimento faz-se de extrema necessidade. Ter conhecimento sobre a concepção do seu projeto, como funcionam, seus pontos fortes e suas fraquezas, são requisitos necessários para a pessoa que deseja estudar esta ciência. O presente trabalho traz uma contextualização histórica da aerodinâmica veicular nas indústrias automotiva e automobilística, além de apresentar aspectos técnicos relacionados aos túneis de vento e simulação computacional. Abordando as vantagens e desvantagens de cada ferramenta, expõe-se o fato de que estas ferramentas são complementares no estudo aerodinâmico. Para exemplificar a utilização dessas ferramentas, foi realizado um estudo aerodinâmico sobre uma geometria básica, que representa com similaridade os veículos tipo hatchback, denominada Modelo SAE em ambiente computacional. Os conceitos acerca do arrasto veicular e estabilidade veicular foram expostos para embasar este estudo. Este modelo foi submetido a diferentes geometrias traseiras e condições de escoamento simétricas e assimétricas. Este estudo demonstrou que o arrasto e a estabilidade veicular compreendem conceitos distintos e, dessa forma, é possível diminuir o arrasto de um veículo sem haver perda de estabilidade.<br>The growing environmental concern and the necessity to create more efficient products have motivated researchers to conduct studies about the aerodynamic vehicle. These two aspects are the main reasons which are promoting a great demand for knowledge in this theme. This science may be considered relatively new and still lacks more databases. Understand how aerodynamics is related to automobiles fuel consumption such as drag resistance imposed to their displacement, is something that has made the automotive industries invest considerable effort in obtaining tools which may represent the normal traffic conditions and thus, able to predict the performance of the product in development stage. The wind tunnels and computer simulations appear in this environment as the main tools for analysis and prediction of the flow around vehicle. The understanding about them is so of utmost necessity. Knowing how it was designed, how they work, their strengths and weaknesses are essential requirements for the person who wants to study this science. This material presents a historical development of vehicle aerodynamics in automotive and motor-racing industries, indeed technical aspects related to wind tunnels and computational fluid dynamics. Exposing the advantages and disadvantages of both tools, it is evidenced these tools complement each other during an aerodynamic study. To exemplify these tools utility an aerodynamic research was conducted using a basic form geometry known as SAE Model that represents with similarity the hatchback vehicles in the market. Drag and vehicle stability concepts were exposed to build a solid basis for this study. This model was submitted to different rear geometries, symmetric and asymmetric flow conditions. It could be demonstrated that drag and vehicle stability have distinct concepts and therefore it is possible diminish the first without damaging the later.
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22

Mariette, Kevin. "Contrôle en boucle fermée pour la réduction active de traînée aérodynamique des véhicules." Thesis, Lyon, 2020. http://www.theses.fr/2020LYSEI088.

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Le contrôle actif de l’écoulement à l’arrière des véhicules se déplaçant à grande vitesse est un moyen de diminuer efficacement la consommation énergétique des véhicules par la réduction de la traînée aérodynamique. L’intérêt des méthodes actives est leur possible adéquation avec des conditions environnementales variables pour une modification minimale de la forme des véhicules, contrairement aux systèmes exclusivement passifs (profilage, ailerons aérodynamiques …). Toutefois, le contrôle actif nécessite un apport d’énergie qui réduit sa rentabilité énergétique finale. À l’aide d’essais expérimentaux sur une maquette de véhicule simplifié, cette thèse recherche comment employer un contrôle actif à base de jets pulsés à haute fréquence pour assurer une réduction de traînée de véhicule performante, robuste et énergétiquement rentable. Ces recherches sont axées sur : (i) la compréhension des phénomènes à l’origine de la traînée de pression, (ii) la définition d’un modèle de l’écoulement pour le contrôle, et (iii) l’implémentation expérimentale de méthodes de contrôle de traînée efficaces, robustes et à moindre coût énergétique. Les tests en soufflerie réalisés au cours de cette thèse se basent sur les stratégies de contrôle par mode glissant et de commande par extremum seeking qui permettent de concevoir de nouvelles solutions de réduction de la traînée visant à l’amélioration de la robustesse et de la rentabilité du contrôle par jets pulsés. Cette thèse s’inscrit dans le projet ANR ActivRoad issu de la collaboration de trois laboratoires de recherche : le Laboratoire Ampère (INSA, Lyon), l’Institut Pprime (ENSMA, Poitiers) et le LMFA (Centrale, Lyon) ; et le soutien de deux acteurs industriels : le groupe PSA et Volvo Trucks<br>Active flow control techniques can decrease the aerodynamic drag acting on a vehicle moving at high velocity. Instead of exclusively passive techniques, active control can reduce the pressure drag on a vehicle under a wider range of operating conditions without requiring large modifications of the functional shape of the vehicles. However, active control devices require an additional source of energy, which may decrease the global efficiency of the control. Our work aims to reduce significantly the drag of ground vehicles with efficiency and robustness thanks to high frequency pulsed jet control. We present experimental studies on a simplified bluff body mock-up of a ground vehicle and we seek to understand the phenomena linked to the pressure drag on a vehicle. In this thesis, we propose a modelling methodology of the vehicle’s turbulent wake adapted for control purposes. Finally, we design and test experimentally different closed-loop control methods of the wake with high frequency pulsed air jets. The experimental studies performed in a wind tunnel show the efficient application of sliding mode control and extremum seeking techniques for a robust drag control with energy cost considerations. This thesis was financed by the French National Research Agency (ANR) and contributes to the project ActivRoad involving three French laboratories: Ampère (INSA, Lyon), Pprime Institute (ENSMA, Poitiers), and the LMFA (Centrale, Lyon); and two automotive companies: PSA group and Volvo Trucks
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23

Sobotka, Vojtěch. "Experimentální ověření konceptu aktivního řízení proudu v automobilní aplikaci." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2017. http://www.nusl.cz/ntk/nusl-319257.

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Tato diplomová práce obsahuje komplexní návrh systému aktivního řízení proudu instalovaného na osobním voze Škoda Roomster. Tato práce navazuje na výzkum provedený VUT a TUB na vozidle Volkswagen UP! Návrh lze rozdělit na tři základní části - návrh spoileru, návrh závěsů a návrh vyfukovacího systému. V každé z těchto částí je návrh detailně popsán a potřebná výkresová dokumentace je součástí práce v její příloze. Pro potřeby návrhu vyfukovacího systému bylo provedeno jeho testování. Výsledky testu jsou v této části uvedeny. Práce také obsahuje komplexní popis sestavení celého systému a jeho instalace na automobil.
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24

Abbasi, Baharanchi Ahmadreza. "Development of a Two-Fluid Drag Law for Clustered Particles Using Direct Numerical Simulation and Validation through Experiments." FIU Digital Commons, 2015. http://digitalcommons.fiu.edu/etd/2489.

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This dissertation focused on development and utilization of numerical and experimental approaches to improve the CFD modeling of fluidization flow of cohesive micron size particles. The specific objectives of this research were: (1) Developing a cluster prediction mechanism applicable to Two-Fluid Modeling (TFM) of gas-solid systems (2) Developing more accurate drag models for Two-Fluid Modeling (TFM) of gas-solid fluidization flow with the presence of cohesive interparticle forces (3) using the developed model to explore the improvement of accuracy of TFM in simulation of fluidization flow of cohesive powders (4) Understanding the causes and influential factor which led to improvements and quantification of improvements (5) Gathering data from a fast fluidization flow and use these data for benchmark validations. Simulation results with two developed cluster-aware drag models showed that cluster prediction could effectively influence the results in both the first and second cluster-aware models. It was proven that improvement of accuracy of TFM modeling using three versions of the first hybrid model was significant and the best improvements were obtained by using the smallest values of the switch parameter which led to capturing the smallest chances of cluster prediction. In the case of the second hybrid model, dependence of critical model parameter on only Reynolds number led to the fact that improvement of accuracy was significant only in dense section of the fluidized bed. This finding may suggest that a more sophisticated particle resolved DNS model, which can span wide range of solid volume fraction, can be used in the formulation of the cluster-aware drag model. The results of experiment suing high speed imaging indicated the presence of particle clusters in the fluidization flow of FCC inside the riser of FIU-CFB facility. In addition, pressure data was successfully captured along the fluidization column of the facility and used as benchmark validation data for the second hybrid model developed in the present dissertation. It was shown the second hybrid model could predict the pressure data in the dense section of the fluidization column with better accuracy.
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25

Zuanetti, Bryan. "Plate Impact Experiments for Studying the Dynamic Response of Commercial-Purity Aluminum at Temperatures Approaching Melt." Case Western Reserve University School of Graduate Studies / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1557132337419911.

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26

Rodriguez, Iara Hernandez. "Estudo do fenômeno de redução de atrito em escoamento disperso óleo - água em tubulação horizontal." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/18/18147/tde-09122009-172115/.

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O interesse em escoamento bifásico líquido-líquido aumentou recentemente, em especial devido às grandes perdas de energia envolvidas no transporte de petróleo, onde comumente uma mistura bifásica óleo-água é deslocada ao longo de grandes distancias. Embora este tipo de escoamento seja comum na indústria, não existem tantos trabalhos na literatura quanto os relacionados ao escoamento gás-líquido. Alguns estudos sobre escoamentos óleo-água reportam uma redução de atrito em dispersões e emulsões em regime turbulento sem adição de qualquer tipo de substancia química, mas a física por trás do fenômeno ainda não é bem compreendida. Neste trabalho, foi estudado o padrão de escoamento disperso óleo-água em tubulação horizontal, visando a obtenção de novos dados experimentais e um melhor entendimento do fenômeno de redução de atrito. Uma série de parâmetros considerados importantes para a caracterização do escoamento foi investigada: queda de pressão, fração volumétrica e sub-padrões de escoamento disperso. Apresentam-se dados de distribuição das fases e fração volumétrica in situ, obtidos através de um moderno sensor intrusivo, do tipo wire-mesh, baseado em medidas de capacitância (permissividade). Câmera de alta velocidade e técnica das válvulas de fechamento rápido foram utilizadas para validar os sinais do sensor. Um modelo prospectivo simplificado foi desenvolvido como uma tentativa de explicar a ocorrência do fenômeno de redução de atrito no padrão disperso óleo-água estudado. O modelo sugere que a presença de uma fina película de água rente a parede hidrofílica/oleofóbica do tubo poderia explicar a diminuição no gradiente de pressão bifásico observada.<br>The interest in two-phase liquid-liquid flow has increased recently mainly due to the petroleum industry where oil and water are often produced and transported together for long distances and the significant frictional pressure gradient involved. Liquid-liquid flows are present in a wide range of industrial processes; however, they have not been studied as intensively as gas-liquid flows. Drag reduction phenomenon in oil-water flows without the addition of any drag reduction agent has been detected in previous works, but the physics behind the phenomenon is yet not well understood. The aim of the research was to study the dispersed oil-water flow pattern in a horizontal pipe in order to better understand the phenomenon and the obtaining of new experimental data of oil-water dispersed flows. Important issues related to oil-water pipe flow were investigated: pressure drop, volume fraction and flow patterns. Phase distribution and holdup data were obtained by a new wire-mesh sensor based on capacitance (permittivity) measurements. A high-speed video camera and the Quick-Closing-Valves technique were used to compare and validate the signals of the wire-mesh sensor. A simplified mathematical model was proposed to explain the drag reduction phenomenon in the oil-water dispersed flow studied. The model suggests that the presence of a thin water film between the homogenously dispersed flow and the pipe wall could explain the observed decreases of the two-phase pressure gradient.
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Carregari, André Luiz. "Estudo do escoamento de ar sobre a carroceria de um ônibus usando um programa de CFD e comparação com dados experimentais." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/18/18135/tde-23082006-090843/.

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Dois dos principais objetivos no estudo da aerodinâmica de veículos comerciais são a redução no consumo de combustível e o aumento na eficiência da refrigeração do motor. Esses objetivos podem ser alcançados através do desenvolvimento de dispositivos que modifiquem o escoamento do ar ao redor do veículo e também através da alteração da forma das superfícies externas. A inclinação das superfícies da parte traseira de um ônibus, por exemplo, tem grande influência sobre a esteira turbulenta que se forma atrás do veículo. O uso de ferramentas computacionais permite uma redução de custo e maior flexibilidade na análise aerodinâmica de autoveículos. Ainda é preciso, no entanto, que o resultado dessas ferramentas computacionais seja verificado com o maior número possível de casos para que se possa escolher e ajustar o modelo matemático de forma adequada. O objetivo do presente trabalho é a verificação dos resultados computacionais e experimentais no desenvolvimento de metodologias que visem à redução no consumo de combustível e aumento na eficiência da refrigeração do motor. Foram comparados resultados experimentais e computacionais do escoamento sobre um modelo de um ônibus comercial em escala 1:17,5. Para a realização do experimento foi utilizado um túnel de vento de seção aberta, onde foram analisadas as distribuições de pressão nas superfícies da carroceria e o arrasto aerodinâmico. Para o teste computacional, foi utilizado um software de dinâmica dos fluidos computacional em que as equações de Navier-Stokes com média de Reynolds são resolvidas pelo método dos volumes finitos usando um modelo de turbulência RNG 'capa' - 'épsilon'<br>Two main objectives in the study of commercial vehicle aerodynamics are the reduction in fuel consumption and the improvement in engine refrigeration efficiency. These objectives can be achieved through development of devices which vary the flow characteristics around the vehicle and also through modification of the shape of external surfaces. The slope of rear surfaces, for instance, has large influence over the wake turbulence which forms behind the vehicle. The use of computational tools yields cost reduction and greater flexibility in automotive aerodynamic analysis. There is still a need, however, for verification of results, generated by these computational tools, with the largest possible number of test cases so that the mathematical model is adequately chosen and adjusted. The objective of the present work is the verification of experimental and computational results in the development of methodologies aiming at reduction of fuel consumption and improvement in engine refrigeration efficiency. Experimental and computational aerodynamic results were compared for a commercial bus model with a 1:17.5 scale. The experiments were conducted in an open section wind tunnel where pressure distribution and aerodynamic drag were analyzed. The numerical analysis was conducted using computational fluid dynamics software which solves the Reynolds Averaged Navier-Stokes equations using the finite volume method with a RNG 'capa' - 'épsilon' turbulence model
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Couldrick, Jonathan Stuart Aerospace Civil &amp Mechanical Engineering Australian Defence Force Academy UNSW. "A study of swept and unswept normal shock wave/turbulent boundary layer interaction and control by piezoelectric flap actuation." Awarded by:University of New South Wales - Australian Defence Force Academy. School of Aerospace, Civil and Mechanical Engineering, 2006. http://handle.unsw.edu.au/1959.4/38672.

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The interaction of a shock wave with a boundary layer is a classic viscous/inviscid interaction problem that occurs over a wide range of high speed aerodynamic flows. For example, on transonic wings, in supersonic air intakes, in propelling nozzles at offdesign conditions and on deflected controls at supersonic/transonic speeds, to name a few. The transonic interaction takes place at Mach numbers typically between 1.1 and 1.5. On an aerofoil, its existence can cause problems that range from a mild increase in section drag to flow separation and buffeting. In the absence of separation the drag increase is predominantly due to wave drag, caused by a rise in entropy through the interaction. The control of the turbulent interaction as applied to a transonic aerofoil is addressed in this thesis. However, the work can equally be applied to the control of interaction for numerous other occurrences where a shock meets a turbulent boundary layer. It is assumed that, for both swept normal shock and unswept normal shock interactions, as long as the Mach number normal to the shock is the same, then the interaction, and therefore its control, should be the same. Numerous schemes have been suggested to control such interaction. However, they have generally been marred by the drag reduction obtained being negated by the additional drag due to the power requirements, for example the pumping power in the case of mass transfer and the drag of the devices in the case of vortex generators. A system of piezoelectrically controlled flaps is presented for the control of the interaction. The flaps would aeroelastically deflect due to the pressure difference created by the pressure rise across the shock and by piezoelectrically induced strains. The amount of deflection, and hence the mass flow through the plenum chamber, would control the interaction. It is proposed that the flaps will delay separation of the boundary layer whilst reducing wave drag and overcome the disadvantages of previous control methods. Active control can be utilised to optimise the effects of the boundary layer shock wave interaction as it would allow the ability to control the position of the control region around the original shock position, mass transfer rate and distribution. A number of design options were considered for the integration of the piezoelectric ceramic into the flap structure. These included the use of unimorphs, bimorphs and polymorphs, with the latter capable of being directly employed as the flap. Unimorphs, with an aluminium substrate, produce less deflection than bimorphs and multimorphs. However, they can withstand and overcome the pressure loads associated with SBLI control. For the current experiments, it was found that near optimal control of the swept and unswept shock wave boundary layer interactions was attained with flap deflections between 1mm and 3mm. However, to obtain the deflection required for optimal performance in a full scale situation, a more powerful piezoelectric actuator material is required than currently available. A theoretical model is developed to predict the effect of unimorph flap deflection on the displacement thickness growth angles, the leading shock angle and the triple point height. It is shown that optimal deflection for SBLI control is a trade-off between reducing the total pressure losses, which is implied with increasing the triple point height, and minimising the frictional losses.
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Svedberg, Anna. "Improvement of the retention-fromation relationship using three-component retention aid systems." Doctoral thesis, KTH, Fiberteknologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-96259.

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Rodriguez, Iara Hernandez. "Estudo experimental e modelagem do escoamento de emulsão inversa em tubulações." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/18/18147/tde-11022015-102532/.

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O escoamento líquido-líquido, em especial o escoamento óleo-água, vem atraindo a atenção de pesquisadores devido à alta demanda pelo combustível fóssil no atual cenário petrolífero mundial e nacional. Os desafios tecnológicos colocados pelas descobertas de reservas de óleos pesados e altamente viscosos consideram, em especial, a preocupação por minimizar as perdas energéticas nas linhas. Emulsões inversas ou dispersões óleo-em-água, na qual o óleo se encontra disperso de maneira uniforme em água, caracteriza-se pela baixa viscosidade aparente, tornando-se um tipo de emulsão desejável em algumas etapas do transporte de petróleo. Esses fatos tornam essencial o estudo deste tipo de padrão para o dimensionamento e operação ótima de dutos de produção de petróleo. Contudo, não existe ainda um número abrangente de trabalhos sobre padrão disperso líquido-líquido, ao comparar com escoamento em fases separadas. Trabalhos sobre dispersões têm reportado redução de atrito sem a adição de substâncias químicas em regime turbulento. No entanto, não há ainda um entendimento satisfatório do fenômeno. Na maioria dos trabalhos, sendo quase todos realizados com óleos leves e pouco viscosos, a redução é reportada em dispersões água-em-óleo, com escassos trabalhos reportando o fenômeno em dispersões óleo-em-água. A pesquisa realizada tratou do estudo experimental e teórico de dispersões óleo-em-água em tubulações. O escoamento foi caracterizado a partir da obtenção de dados de holdup, gradiente de pressão por fricção, distribuição das fases e padrão de escoamento. Uma teoria foi proposta para explicar a redução de atrito detectada neste trabalho, baseada na existência de um filme fino de água que escoa em contato com a parede do tubo, a baixos números de Reynolds, evitando o contato direto do núcleo turbulento (mistura bifásica) com a parede do tubo. O referido filme líquido foi detectado e quantificado utilizando-se técnica visual. Além disso, um modelo dinâmico baseado na teoria de lubrificação hidrodinâmica foi desenvolvido como tentativa de explicar a formação do filme líquido parietal no escoamento turbulento de dispersões óleo-água.<br>Liquid-liquid flow, especially oil-water flow, has attracted the attention of researchers due to the high demand for petroleum in the current global scenario. The discovery of reserves of heavy and highly viscous oils creates new challenges which are mainly concerned with reducing the significant pressure drop in pipes. Inverse emulsion or oil-in-water dispersions in which the oil is dispersed in water is characterized by its low effective viscosity, making it a desirable type of emulsion in some steps of oil production. These facts make the study of dispersed liquid-liquid flow essential for the design and optimal operation of oil pipelines. However, the studies on such flow pattern are scanty in comparison to those on separate flows, as stratified and annular flow patterns. Drag reduction in oil-water turbulent flow without the addition of any chemical substance has been reported in some studies. This phenomenon has received increasing attention in recent years, because there is not a satisfactory understanding of its dynamics yet. Most studies, almost all using light oils, report drag reduction in dispersion of water-in-oil, with few studies reporting the phenomenon in oil-in-water dispersions. This research comprises an experimental and theoretical study on oil-in-water dispersions in pipes. Pressure gradient, holdup, phase distribution and flow patterns data were obtained to characterize the two-phase flow. A theory was proposed to explain the drag reduction detected in this work, based on the existence of a thin water film flowing in contact with the pipe wall at low Reynolds numbers, avoiding contact between the turbulent core (mixture) and the pipe wall. The liquid film was detected and quantified using visual technique. In addition, a dynamic model based on the hydrodynamic lubrication theory was developed as an attempt to explain the formation of the liquid film.
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31

Pereira, E. "Adaptive closed-loop control of arterial pressure during anaesthesia." Thesis, University of Bristol, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379565.

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32

Cantoni, Lorenzo. "Load Control Aerodynamics in Offshore Wind Turbines." Thesis, KTH, Kraft- och värmeteknologi, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-291417.

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Due to the increase of rotor size in horizontal axis wind turbine (HAWT) during the past 25 years in order to achieve higher power output, all wind turbine components and blades in particular, have to withstand higher structural loads. This upscalingproblem could be solved by applying technologies capable of reducing aerodynamic loads the rotor has to withstand, either with passive or active control solutions. These control devices and techniques can reduce the fatigue load upon the blades up to 40% and therefore less maintenance is needed, resulting in an important money savings for the wind farm manager. This project consists in a study of load control techniques for offshore wind turbines from an aerodynamic and aeroelastic point ofview, with the aim to assess a cost effective, robust and reliable solution which could operate maintenance free in quite hostile environments. The first part of this study involves 2D and 3D aerodynamic and aeroelastic simulations to validate the computational model with experimental data and to analyze the interaction between the fluid and the structure. The second part of this study is an assessment of the unsteady aerodynamic loads produced by a wind gust over the blades and to verify how a trailing edge flap would influence the aerodynamic control parameters for the selected wind turbine blade.<br>På grund av ökningen av rotorstorleken hos horisontella vindturbiner (HAWT) under de senaste 25 åren, en design som har uppstod för att uppnå högre effekt, måste alla vindkraftkomponenter och blad stå emot högre strukturella belastningar. Detta uppskalningsproblem kan lösas genom att använda metoder som kan minska aerodynamiska belastningar som rotorn måste tåla, antingen med passiva eller aktiva styrlösningar. Dessa kontrollanordningar och tekniker kan minska utmattningsbelastningen på bladen med upp till 40 % och därför behövs mindre underhåll, vilket resulterar i viktiga besparingar för vindkraftsägaren. Detta projekt består av en studie av lastkontrolltekniker för havsbaserade vindkraftverk ur en aerodynamisk och aeroelastisk synvinkel, i syfte att bedöma en kostnadseffektiv, robust och pålitlig lösning som kan fungera underhållsfri i tuffa miljöer. Den första delen av denna studie involverar 2D- och 3D-aerodynamiska och aeroelastiska simuleringar för att validera beräkningsmodellen med experimentella data och för att analysera interaktionen mellan fluiden och strukturen. Den andra delen av denna studie är en bedömning av de ojämna aerodynamiska belastningarna som produceras av ett vindkast över bladen och för att verifiera hur en bakkantklaff skulle påverka de aerodynamiska styrparametrarna för det valda vindturbinbladet.
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Wong, Lai-har Teresa. "Drug dependency and the experience of young offenders in a residential drug treatment institution." Hong Kong : University of Hong Kong, 1998. http://sunzi.lib.hku.hk/hkuto/record.jsp?B20621905.

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34

Alqadi, Abdulaziz Abdullah. "Studies of antihypertensive drug persistence and adherence in the Glasgow Blood Pressure Clinic." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/7664/.

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Hypertension (HTN) is a major risk factor for cardiovascular diseases including stroke, coronary heart disease (CHD), chronic renal failure, peripheral vascular disease, myocardial infarction, congestive heart failure and premature death. The prevalence of HTN in Scotland is very high and although a high proportion of the patients receive antihypertensive medications, blood pressure (BP) control is very low. Recommendations for starting a specific antihypertensive class have been debated between various guidelines over the years. Some guidelines and HTN studies have preferred to start with a combination of an antihypertensive class instead of using a single therapy, and they have found greater BP reductions with combination therapies than with monotherapy. However, it has been shown in several clinical trials that 20% to 35% of hypertensive patients could not achieve the target BP, even though they received more than three antihypertensive medications. Several factors were found to affect BP control. Adherence and persistence were considered as the factors contributing the most to uncontrolled hypertension. Other factors such as age, sex, body mass index (BMI), alcohol intake, baseline systolic BP (SBP), and the communication between physicians and patients have been shown to be associated with uncontrolled BP and resistant hypertension. Persistence, adherence and compliance are interchangeable terms and have been used in the literature to describe a patient’s behaviour with their antihypertensive drugs and prescriptions. The methods used to determine persistence and adherence, as well as the inclusion and exclusion criteria, vary between persistence and adherence studies. The prevalence of persistence and adherence have varied between these studies, and were determined to be high in some studies and low in others. The initiation of a specific antihypertensive class has frequently been associated with an increase or decrease in adherence and persistence. The tolerability and efficacy of the initial antihypertensive class have been the most common methods of explaining this association. There are also many factors that suggest a relationship with adherence and persistence. Some factors in previous studies, such as age, were frequently associated with adherence and persistence. On the other hand, relationships with certain factors have varied between the studies. The associations of age, sex, alcohol use, smoking, baseline systolic blood pressure (SBP) and diastolic BP (DBP), the presence of comorbidities, an increase in the number of pills and the relationship between patients and physicians with adherence and persistence have been the most commonly investigated factors. Most studies have defined persistence in terms of a patient still taking medication after a period of time. A medication possession ratio (MPR) ≥ 80 has been used to define compliance. Either of these terminologies, or both, have been used to estimate adherence. In this study, I used the same definition for persistence to identify patients who have continued with their initial treatment, and used persistence and MPR to define patients who adhered to their initial treatment. The aim of this study was to estimate the prevalence of persistence and adherence in Scotland. Also, factors that could have had an effect on persistence and adherence were studied. The number of antihypertensive drugs taken by patients during the study and factors that led to an increase in patients being on a combination therapy were also evaluated. The prevalence of resistance and BP control were determined by taking the BP after the last drug had been taken by persistent patients during five follow-up studies. The relationship of factors such as age, sex, BMI, alcohol use, smoking, estimated glomerular filtration rate (eGFR), and albumin levels with BP reductions for each antihypertensive class were determined. Information Services Division (ISD) data, which includes all antihypertensive drugs, were collected from pharmacies in Scotland and linked to the Glasgow Blood Pressure Clinic (GBPC) database. This database also includes demographic characteristics, BP readings and clinical results for all patients attending the GBPC. The case notes for patients who attended the GBPC were reviewed and all new antihypertensive drugs that were prescribed between visits, BP before and after taking drugs, and any changes in the hypertensive drugs were recorded. A total of 4,232 hypertensive patients were included in the first study. The first study showed that angiotensin converting enzyme inhibitor (ACEI) and beta-blockers (BB) were the most prescribed antihypertensive classes between 2004 and 2013. Calcium channel blockers (CCB), thiazide diuretics and angiotensin receptor blockers (ARB) followed ACEI and BB as the most prescribed drugs during the same period. The prescription trend of the antihypertensive class has changed over the years with an increase in prescriptions for ACEI and ARB and a decrease in prescriptions for BB and diuretics. I observed a difference in antihypertensive class prescriptions by age, sex, SBP and BMI. For example, CCB, thiazide diuretics and alpha-blockers were more likely to be prescribed to older patients, while ACEI, ARB or BB were more commonly prescribed for younger patients. In a second study, 4,232 and 3,149 hypertensive patients were included to investigate the prevalence of persistence in the Scottish population in 1- and 5-year studies, respectively. The prevalence of persistence in the 1-year study was 72.9%, while it was only 62.8% in the 5-year study. Those patients taking ARB and ACEI showed high rates of persistence and those taking diuretics and alpha blockers had low rates of persistence. The association of persistence with clinical characteristics was also investigated. Younger patients were more likely to totally stop their treatment before restarting their treatment with other antihypertensive drugs. Furthermore, patients who had high SBP tended to be non-persistent. In a third study, 3,085 and 1,979 patients who persisted with their treatment were included. In the first part of the study, MPR was calculated, and patients with an MPR ≥ 80 were considered as adherent. Adherence rates were 29.9% and 23.4% in the 1- and 5-year studies, respectively. Patients who initiated the study with ACEI were more likely to adhere to their treatments. However, patients who initiated the study with thiazide diuretics were less likely to adhere to their treatments. Sex, age and BMI were different between the adherence and non-adherence groups. Age was an independent factor affecting adherence rates during both the 1- and 5-year studies with older patients being more likely to be adherent. In the second part of the study, pharmacy databases were checked with patients' case notes to compare antihypertensive drugs that were collected from the pharmacy with the antihypertensive prescription given during the patient’s clinical visit. While 78.6% of the antihypertensive drugs were collected between clinical visits, 21.4% were not collected. Patients who had more days to see the doctor in the subsequent visit were more likely to not collect their prescriptions. In a fourth study, 3,085 and 1,979 persistent patients were included to calculate the number of antihypertensive classes that were added to the initial drug during the 1-year and 5-year studies, respectively. Patients who continued with treatment as a monotherapy and who needed a combination therapy were investigated during the 1- and 5-year studies. In all, 55.8% used antihypertensive drugs as a monotherapy and 44.2% used them as a combination therapy during the 1-year study. While 28.2% of patients continued with treatment without the required additional therapy, 71.8% of the patients needed additional therapy. In all, 20.8% and 46.5% of patients required three different antihypertensive classes or more during the 1-year and 5-year studies, respectively. Patients who started with ACEI, ARB and BB were more likely to continue as monotherapy and less likely to need two more antihypertensive drugs compared with those who started with alpha-blockers, non-thiazide diuretics and CCB. Older ages, high BMI levels, high SBP and high alcohol intake were independent factors that led to an increase in the probability of patients taking combination therapies.
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35

Trenor, Scott Russell. "An Examination of Transdermal Drug Delivery Using a Model Polyisobutylene Pressure Sensitive Adhesive." Master's thesis, Virginia Tech, 2001. http://hdl.handle.net/10919/37141.

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This work was performed as a preliminary transdermal drug delivery (TDD) study to investigate the diffusion characteristics and effects of skin surfactants in vitro of four active ingredients on a poly(dimethyl siloxane) polycarbonate copolymer membrane. A Franz-type diffusion cell and various receptor solutions were used. The adhesive used was comprised of a polyisobutylene-based pressure sensitive adhesive manufactured by Adhesives Research Inc. High performance liquid chromatography was used to analyze the diffusion characteristics of these systems. In addition, the effects of two skin surfactants (sodium lauryl sulfate and dimethyl sulfoxide) on the adhesive were also investigated. Results from peel testing and thermal analysis showed that the peel strength, glass transition, and softening temperature of the adhesive was greatly reduced with the addition of the surfactants.<br>Master of Engineering
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36

Nilsson, Annika. "Bacterial adaptation to novel selection pressures /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-192-X/.

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37

Cleaveland, Bonnie L. "Development and validation of a behavioral measure of drug refusal skills in seventh and eighth graders." Diss., This resource online, 1996. http://scholar.lib.vt.edu/theses/available/etd-06062008-151349/.

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38

Makeen, Hafiz Antar Mohammad. "Analysis of anti-cancer drug penetration through multicell layers in vitro : the development and evaluation of an in vitro model for assessing the impact of convective fluid flow on drug penetration through avascular cancer tissues." Thesis, University of Bradford, 2012. http://hdl.handle.net/10454/5681.

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High interstitial fluid pressure (IFP) in tumours is recognized as a barrier to drug delivery resulting in reduced efficacy. High IFP impedes the normal process of convective fluid flow (CFF) from blood vessels into the interstitium. The aim of this study was to develop an in vitro model that could be used to measure CFF and to study its effects on drug delivery. The model consists of a transwell cell culture insert which supports the growth of multicell layers (MCL) on collagen coated membranes. A graduated tube is inserted into the transwell and a pressure gradient is applied across the membrane by raising the volume of medium in the tube above that of the bottom chamber. CFF is determined by measuring the weight of medium in the bottom chamber as a function of time. CFF was inversely proportional to MCL thickness and 41.1±3.6µm thick MCL has completely stopped CFF. Using a physiologically relevant hydrostatic pressure of 28mmHg, a CFF of 21µL/min was recorded using a DLD-1 MCL that was 12.21±3.2µm thick. Under these conditions, the rates of penetration of doxorubicin, imatinib and gefitinib were respectively 42, 26 and 13 folds greater than when no CFF exists. Reversing the CFF so that it opposed the drug diffusion gradient significantly impairs drug penetration. In conclusion, a novel in vitro model for assessing the impact of CFF on drug delivery has been developed. This model could be used to evaluate strategies designed to increase drug delivery to solid tumours by modifying the CFF.
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39

HAMAJIMA, NOBUYUKI, YOSHITOKU YOSHIDA, AMONOV MALIK, SALIM DAVLATOV, and ERKIN TOIROV. "HYPERTENSION-RELATED KNOWLEDGE, PRACTICE AND DRUG ADHERENCE AMONG INPATIENTS OF A HOSPITAL IN SAMARKAND, UZBEKISTAN." Nagoya University School of Medicine, 2014. http://hdl.handle.net/2237/20544.

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40

Thomas, KaMala S. "Mediators of heightened pressor responses to phenylephrine." Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3258329.

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Thesis (Ph. D.)--University of California, San Diego and San Diego State University, 2007.<br>Title from first page of PDF file (viewed May 29, 2007). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references (p. 57-65).
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41

Shakir, Ali M. "A prototype multifunction differential pressure-flow sensor for medical and industrial applications." Diss., Online access via UMI:, 2009.

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Thesis (Ph. D.)--State University of New York at Binghamton, Thomas J. Watson School of Engineering and Applied Science, Department of Systems Science and Industrial Engineering, 2009..<br>Includes bibliographical references.
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42

Hatton, R. "The role of angiotensin in the control of blood pressure : a functional interaction with the autonomic nervous system." Thesis, Open University, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.378202.

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An interaction of the renin-angiotensin system and the autonomic nervous system was demonstrated in vivo during activation of the former by sodium depletion in the dog and the latter during application of lower body negative pressure (LBNP) in the cat. In the dog, inhibitors of angiotensin converting enzyme (ACE), teprotide and captopril, together with an angiotensin II (AII) antagonist, saralasin, and a peptide inhibitor of renin, H77, given intravenously lowered blood pressure (BP) by reducing peripheral resistance in relation to the prevailing level of plasma renin activity (PRA). They did so without changing cardiac output or heart rate as PRA rose above the resting level. The lack of tachycardia was due to a resetting of the baroreflex without a change in sensitivity as teprotide unmasked an action of AII at a peripheral site since when administered into a lateral cerebral ventricle it was ineffective. In the cat, teprotide and saralasin enhanced the fall in BP induced by LBNP and impaired its recovery. When these inhibitors were given during LBNP, a greater and more sustained fall in BP was seen than with either inhibitor alone. This occurred before activation of plasma renin and was not associated with a reduction in sympathetic efferent nerve activity. Further studies revealed that teprotide, captopril and enalapril interfered with neurogenic vasoconstriction involving AII in pithed rats and moreover, captopril was active in lowering BP in two strains of rat shown to be particularly sensitive to the adrenergic potentiating effect of AII. These findings have provided physiological evidence in vivo supporting a peripheral interaction between the autonomic nervous system and AII even at low levels of activation which potentiate adrenergic mechanisms and maintain homeostatic reflexes. They suggest that a significant part of the hypotensive activity of ACE inhibitors is due to interference with facilitatory actions of AII on the autonomic nervous system.
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43

Casper, Brett Joseph. "Youth's Perceptions of Social and Cultural Dimensions of Drug Use." PDXScholar, 1994. https://pdxscholar.library.pdx.edu/open_access_etds/4720.

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This study explores youth's perceptions and understanding of the social phenomenon of drugs in our society. Sixty-four students (32 fourth graders and 32 eleventh graders), selected from schools in the Portland Public School District participated individually in a one hour interview where they responded to open ended questions that probed for their perceptions of drug use. Participants were also asked to describe their feelings regarding anti-drug messages they view in the media and their comments regarding the "Just Say NO" program. The tape-recorded interviews were transcribed and half were used to develop a code that captured recurring themes in the data. Using the code book, five trained individuals coded the 64 transcripts. Reliability, assessed by computing Cohen's Kappa on half the interviews, ranged from .62 to .75, with an average reliability of .69. Seventeen themes derived from the content analysis were discussed which confirm the dramatic impact the peer group has on drug use as well as demonstrate age differences associated with perceptions of anti-drug messages. One hundred percent of the participants noted that there are peer influences promoting drug use. Eleventh graders were more likely than fourth graders to note that drugs are used as a means to escape, overcome constraints or for pleasurable stimulation. Fourth graders were more positive in their responses to the anti-drug commercials and the "Just Say NO" campaign. This research provides information regarding the perceptions of young people that can potentially broaden the dialogue of program planners as well as increase the effectiveness of anti-drug programs and messages.
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44

Cui, Yong. "Enhanced Release of Lidocaine From Supersaturated Solutions of Lidocaine In A Pressure Sensitive Adhesive." The Ohio State University, 2003. http://rave.ohiolink.edu/etdc/view?acc_num=osu1054210962.

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45

Zarnke, Kelly B. "Hypertension management using home blood pressure monitors and patient-initiated drug dosage adjustments, a randomized equivalence trial." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0033/MQ30705.pdf.

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46

Raniseski, Jean Marie Anne 1966. "Conformity disposition and perceived peer pressure: implications for the treatment of drug and alcohol abuse among adolescents." Thesis, The University of Arizona, 1990. http://hdl.handle.net/10150/558134.

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47

Pugach, Pavel. "The evolutionary response of the HIV-1 ENV complex to selection pressures in vitro /." Access full-text from WCMC:, 2007. http://proquest.umi.com/pqdweb?did=1428842531&sid=4&Fmt=2&clientId=8424&RQT=309&VName=PQD.

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48

Baumgart, Johannes. "The Hair Bundle: Fluid-Structure Interaction in the Inner Ear." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-63810.

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A multitude of processes cooperate to produce the sensation of sound. The key initial step, the transformation from mechanical motion into an electrical signal, takes place in highly specialized mechanosensitive organelles that are called hair bundles due to their characteristic appearance. Each hair bundle comprises many apposed cylindrical stereocilia that are located in a liquid-filled compartment of the inner ear. The viscous liquid surrounding the hair bundle dissipates energy and dampens oscillations, which poses a fundamental physical challenge to the high sensitivity and sharp frequency selectivity of hearing. To understand the structure-function relationship in this complex system, a realistic physical model of the hair bundle with an appropriate representation of the fluid-structure interactions is needed to identify the relevant physical effects. In this work a novel approach is introduced to analyze the mechanics of the fluid-structure interaction problem in the inner ear. Because the motions during normal mechanotransduction are much smaller than the geometrical scales, a unified linear system of equations describes with sufficient accuracy the behavior of the liquid and solid in terms of a displacement variable. The finite-element method is employed to solve this system of partial differential equations. Based on data from the hair bundle of the bullfrog's sacculus, a detailed model is constructed that resolves simultaneously the interaction with the surrounding liquid as well as the coupling liquid in the narrow gaps between the individual stereocilia. The experimental data are from high-resolution interferometric measurements at physiologically relevant amplitudes in the range from a fraction of a nanometer to several tens of nanometers and over a broad range of frequencies from one millihertz to hundred kilohertz. Different modes of motion are analyzed and their induced viscous drag is calculated. The investigation reveals that grouping stereocilia in a bundle dramatically reduces the total drag as compared to the sum of the drags on individual stereocilia moving in isolation. The stereocilia in a hair bundle are interconnected by oblique tip links that transmit the energy in a sound to the mechanotransduction channels and by horizontal top connectors that provide elastic coupling between adjacent stereocilia. During hair-bundle deflections, the tip links induce additional drag by causing small but very dissipative relative motions between stereocilia; this effect is offset by the horizontal top connectors that restrain such relative movements, assuring that the hair bundle moves as a unit and keeping the total drag low. In the model the stiffness of the links, the stiffness of the stereocilia, and the geometry are carefully adjusted to match experimental observations. The references are stiffness and drag measurements, as well as the coherence measurements for the bundle's opposite edges, both with and without the tip links. The results are further validated by a comparison with the relative motions measured in a sinusoidally stimulated bundle for the distortion frequencies at which movements are induced by the nonlinearity imposed by channel gating. The model of the fluid-structure interactions described here provides insight into the key step in the perception of sound and the method presented provides an efficient and reliable approach to fluid-structure interaction problems at small amplitudes<br>Bei der Hörwahrnehmung eines Klangs spielen viele komplexe Prozesse zusammen. Der Schlüsselprozess, die Umwandlung mechanischer Schwingungsbewegung in elektrische Signale, findet in den Haarbündeln im Innenohr statt. Diese Haarbündel sind hoch entwickelte mechanosensitive Organellen, bestehend aus vielen nahe beieinander stehenden Stereozilien umgeben von Flüssigkeit. Die beträchtliche Viskosität dieser Flüssigkeit führt zur Energiedissipation und zur Schwingungsdämpfung, was im Gegensatz zur bekannten hohen Empfindlichkeit und der ausgezeichneten Frequenzselektivität der Hörwahrnehmung steht. Um die Komponenten des Haarbündelsystems in ihrem funktionalen Zusammenspiel besser zu verstehen, bedarf es eines wirklichkeitsgetreuen Modells unter Einbeziehung der Wechselwirkung zwischen Flüssigkeit und Struktur. Mit dieser Arbeit wird ein neuer Ansatz vorgestellt, um die Mechanik der Fluid-Struktur-Wechselwirkung im Innenohr zu analysieren. Da die Bewegungen bei der normalen Mechanotransduktion wesentlich kleiner als die geometrischen Abmessungen sind, ist es möglich, das Verhalten von Fluid und Struktur in Form der Verschiebungsvariable in einem linearen einheitlichen System von Gleichungen ausreichend genau zu beschreiben. Dieses System von partiellen Differentialgleichungen wird mit der Finite-Elemente-Methode gelöst. Basierend auf experimentell ermittelten Daten vom Haarbündel des Ochsenfrosches wird ein detailliertes Modell erstellt, welches sowohl die Interaktion mit der umgebenden Flüssigkeit als auch die koppelnde Flüssigkeit in den engen Spalten zwischen den einzelnen Stereozilien erfasst. Die experimentellen Daten sind Ergebnisse von hochauflösenden interferometrischen Messungen bei physiologisch relevanten Bewegungsamplituden im Bereich von unter einem Nanometer bis zu mehreren Dutzend Nanometern, sowie über einen breiten Frequenzbereich von einem Millihertz bis hundert Kilohertz. Das Modell erlaubt die Berechnung der auftretenden viskosen Widerstände aus der numerischen Analyse der verschiedenen beobachteten Bewegungsmoden. Es kann gezeigt werden, dass durch die Gruppierung zu einem Bündel der Gesamtwiderstand drastisch reduziert ist, im Vergleich zur Summe der Widerstände einzelner Stereozilien, die sich individuell und unabhängig voneinander bewegen. Die einzelnen Stereozilien in einem Haarbündel sind durch elastische Strukturen mechanisch miteinander verbunden: Die Energie des Schalls wird durch schräg angeordnete sogenannte Tiplinks auf die mechanotransduktiven Kanäle übertragen, wohingegen horizontale Querverbindungen die Stereozilien direkt koppeln. Während der Haarbündelauslenkung verursachen die Tiplinks zusätzlichen Widerstand durch stark dissipative Relativbewegungen zwischen den Stereozilien. Die horizontalen Querverbindungen unterdrücken diese Bewegungen und sind dafür verantwortlich, dass sich das Haarbündel als Einheit bewegt und der Gesamtwiderstand gering bleibt. Die Steifigkeit der Stereozilien und der Verbindungselemente sowie deren Geometrie sind in dem Modell sorgfältig angepasst, um eine Übereinstimmung mit den Beobachtungen aus verschiedenen Experimenten zu erzielen. Als Referenz dienen Steifigkeits- und Widerstandsmessungen, sowie Kohärenzmessungen für die gegenüberliegenden Außenkanten des Bündels, die jeweils mit und ohne Tiplinks durchgeführt wurden. Darüberhinaus sind die Ergebnisse durch den Vergleich mit experimentell beobachteten Relativbewegungen validiert, die das Haarbündel infolge von sinusförmiger Anregung bei Distorsionsfrequenzen zeigt. Diese haben ihren Ursprung in dem nichtlinearen Prozess des öffnens von Ionenkanälen. Das entwickelte Modell eines Haarbündels liefert neue Einblicke in den Schlüsselprozess der auditiven Wahrnehmung. Zur Behandlung von Problemen der Fluid-Struktur-Wechselwirkungen bei kleinen Amplituden hat sich der hier ausgearbeitete Ansatz als effizient und zuverlässig erwiesen
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49

BOUDJENANE, NASR EDDINE. "Ecoulement des melanges liquides-solides en conduites horizontale et verticale : perte de charge et reduction de frottement." Université Louis Pasteur (Strasbourg) (1971-2008), 1987. http://www.theses.fr/1987STR13148.

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Etude de la perte de charge et du mode d'ecoulement pour des melanges liquide solide en conduites horizontales et verticales. On met en evidence deux categories de particules : particules fines a ecoulement heterogene. On obtient une reduction de frottement de 45 % en ajoutant une quantite de particules fines au melange eau et grosses particules
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50

Zajakowki, Susan M. "The effect of consumption pattern on tolerance to caffeine." Virtual Press, 1995. http://liblink.bsu.edu/uhtbin/catkey/941355.

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The effect of caffeine consumption on blood pressure has been widely studied. Robertson et al. (J Clin Invest 67: 1111-1117, 1981) cited findings of tolerance to humoral and hemodynamic effects from caffeine within four days when caffeine is consumed with each meal. These findings of tolerance have not been verified. The purpose of this study was to determine the effect of caffeine intake pattern on the development of tolerance to hemodynamic effects of caffeine. Fourteen volunteers were randomly assigned to two groups of seven. One group received 250 mg of caffeine in the morning only (MO), the other group received 250 mg of caffeine in the morning, afternoon, and evening (All Day-AD). Subjects underwent a seven day trial during which blood pressure (BP) and heart rate (HR) were assessed; morning beverage (250 mg of caffeine) was ingested and BP and HR assessments were obtained every 10 minutes for 50 minutes at rest, and after 10 minutes of cycling at 100 Watts. Afternoon and evening beverages were consumed which contained 250 mg caffeine each or placebo. No significant change in SBP, DBP, or HR from rest to 40 minutes post-caffeine absorption or between caffeine dosing pattern across trial days was found. A main effect was found for SBP post caffeine consumption (MO=5.4 vs. AD= 1.3). Mean values for DBP were stable across days 3-7 (M0=3.14-4.7 mmHg) but decreased from (3.86-.14 mmHg) from days 3 to 7 (AD). SBP revealed a significant interaction during exercise and across trial days. SBP and HR for the morning only group was higher than the all day caffeine consumption group across days. However DBP was lower across days for the morning only vs. the all day intake pattern. Therefore, caffeine dosing pattern does not appear to have an effect on tolerance to the hemodynamic effects of caffeine at rest or during exercise.<br>School of Physical Education
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