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Relevant bibliographies by topics / DRD2 receptors polymorphisms

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Academic literature on the topic 'DRD2 receptors polymorphisms'

Author: Grafiati

Published: 6 June 2025

Last updated: 25 July 2025

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Journal articles on the topic "DRD2 receptors polymorphisms"

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Eisenberg, Dan T. A., Benjamin Campbell, James MacKillop, et al. "Polymorphisms in the Dopamine D4 and D2 Receptor Genes and Reproductive and Sexual Behaviors." Evolutionary Psychology 5, no. 4 (2007): 147470490700500. http://dx.doi.org/10.1177/147470490700500402.

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Human reproductive and sexual behaviors are heritable and may represent integral life history traits that are likely partially subserved by the dopamine system. Two dopamine receptor polymorphisms, DRD4 48bp VNTR and DRD2 TaqI A, were examined in relation to the Sexual-Orientation Inventory (SOI), age at first sexual intercourse, desired age of marriage, and desired age to have children in 195 (45% male) individuals from a general student population. As DRD4 7R alleles have been associated with migratory behavior, we also examined whether those with more 7R alleles had a greater frequency of m

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Syamsuddin, Saidah, Irawan Yusuf, Jayalangkara Tanra, and Irfan Idris. "The Polymorphisms of DRD2 141-C Ins/Del Receptor Influenced the Treatment Responses of Schizophrenia Patients." Neuropsychiatry 9, no. 5 (2019): 4. https://doi.org/10.5281/zenodo.13594392.

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Polymorphisms of DRD2 receptors lead to vary in the treatment responses of schizophrenia patients. Objectives: This study carried out to know the association of polymorphisms of DRD2 141-C Del/Ins receptors to the doses needed of antipsychotic drug, length of hospital stay, and improvement of symptoms of schizophrenia patients. Methods: The 208 of schizophrenia patients recruited in this study, was hospitalized and have given haloperidol (first generation of antipsychotic drug) then the treatment responses were evaluated by CGI score. The genotyping of the blood performed for DRD2 receptors po

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Vaiman, Elena E., Natalia A. Shnayder, Maxim A. Novitsky, et al. "Candidate Genes Encoding Dopamine Receptors as Predictors of the Risk of Antipsychotic-Induced Parkinsonism and Tardive Dyskinesia in Schizophrenic Patients." Biomedicines 9, no. 8 (2021): 879. http://dx.doi.org/10.3390/biomedicines9080879.

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(1) Introduction: Extrapyramidal disorders form the so-called extrapyramidal syndrome (EPS), which is characterized by the occurrence of motor disorders as a result of damage to the basal ganglia and the subcortical-thalamic connections. Often, this syndrome develops while taking medications, in particular antipsychotics (APs). (2) Purpose: To review studies of candidate genes encoding dopamine receptors as genetic predictors of development of AP-induced parkinsonism (AIP) and AP-induced tardive dyskinesia (AITD) in patients with schizophrenia. (3) Materials and Methods: A search was carried o

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Boiko, A. S., I. V. Pozhidaev, O. Z. Paderina, and A. V. Semke. "Genes of dopamine receptors and transporter in patients with schizophrenia: associations with the clinical characteristics of the disorder." V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY, no. 4-1 (December 9, 2019): 93–94. http://dx.doi.org/10.31363/2313-7053-2019-4-1-93-94.

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Genotyping of 28 polymorphisms of 5 dopamine receptor genes and 12 polymorphisms of dopamine transporter gene was performed in 475 schizophrenia patients and 135 healthy individuals. Associations of several polymorphisms of the DRD2, DRD3 and SLC6A3 genes were identified with leading symptoms and late debut of schizophrenia.

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Paderina, Diana Z., Anastasiia S. Boiko, Ivan V. Pozhidaev, et al. "The Gender-Specific Association of DRD2 Polymorphism with Metabolic Syndrome in Patients with Schizophrenia." Genes 13, no. 8 (2022): 1312. http://dx.doi.org/10.3390/genes13081312.

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Background: Metabolic syndrome is widespread in patients with schizophrenia receiving long-term antipsychotic therapy. Dopamine D2 receptors play an important role in mediating both the therapeutic actions of antipsychotics and their side effects. The present study examined the association of two polymorphisms of the DRD2 gene with metabolic syndrome in patients with schizophrenia. Methods: We examined 517 patients from several regions of Siberia (Russia) with a clinical diagnosis of schizophrenia. Genotyping of two single nucleotide polymorphisms rs1799732 and rs4436578 of the dopamine D2 rec

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Szczerbal, I., J. Nowacka-Woszuk, M. Racka, et al. "Cytogenetic mapping and STR polymorphism of two candidate genes (<i>DRD2</i> and <i>HTR1D</i>) for behaviour traits in four canids (short communication)." Archives Animal Breeding 50, no. 4 (2007): 412–17. http://dx.doi.org/10.5194/aab-50-412-2007.

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Abstract. The dopamine D2 receptor (DRD2) and serotonin receptors 1D (HTR1D) are candidate genes for behavioural traits. In the present study, we show chromosomal location and polymorphism of these genes in four species from the family Canidae: dog (CFA), red fox (VVU), arctic fox (ALA) and the Chinese raccoon dog (NPP). Using fluorescence in situ hybridisation (FISH) the DRD2 gene was localized in the following chromosomes: CFA5q12-13, VVU12q21, ALA10q14 and NPP3q14 and the HTR1D gene was mapped to: CFA2q25, VVU2q22, ALA8q25 and NPP10q25. A microsatellite marker (TG)n in intron 3 of the DRD2

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Park, Hae-Yeon, Hyun-Mi Oh, Tae-Woo Kim, et al. "Single Nucleotide Polymorphisms May Increase the Risk of Aspiration Pneumonia in Post-Stroke Patients with Dysphagia." Current Issues in Molecular Biology 44, no. 8 (2022): 3735–45. http://dx.doi.org/10.3390/cimb44080255.

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This study aimed to evaluate whether genetic polymorphism is associated with an increased risk of infection, specifically post-stroke aspiration pneumonia. Blood samples were obtained from a total of 206 post-stroke participants (males, n = 136; mean age, 63.8 years). Genotyping was performed for catechol-O-methyltransferase (rs4680, rs165599), dopamine receptors (DRD1; rs4532, DRD2; rs1800497, DRD3; rs6280), brain-derived neurotrophic factor (rs6265), apolipoprotein E (rs429358, rs7412), and the interleukin-1 receptor antagonist gene (rs4251961). The subjects were stratified into two groups,

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Colzato, Lorenza S., Heleen A. Slagter, Mischa de Rover, and Bernhard Hommel. "Dopamine and the Management of Attentional Resources: Genetic Markers of Striatal D2 Dopamine Predict Individual Differences in the Attentional Blink." Journal of Cognitive Neuroscience 23, no. 11 (2011): 3576–85. http://dx.doi.org/10.1162/jocn_a_00049.

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The attentional blink (AB)—a deficit in reporting the second of two target stimuli presented in close succession in a rapid sequence of distracters—has been related to processing limitations in working memory. Given that dopamine (DA) plays a crucial role working memory, the present study tested whether individual differences in the size of the AB can be predicted by differences in genetic predisposition related to the efficiency of dopaminergic pathways. Polymorphisms related to mesocortical and nigrostriatal dopaminergic pathways were considered, as well as polymorphisms related to norepinep

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Blokhina ., Е. A., E. М. Krupitsky, А. O. Kibitov, et al. "Exploring genetic predictors of naltrexone treatment response in opioid use disorder." V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY, no. 4-1 (December 9, 2019): 61–64. http://dx.doi.org/10.31363/2313-7053-2019-4-1-61-64.

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Purpose: The present study was aimed to evaluate the effect of the opioid receptors genes and dopamine system genes polymorphisms on the treatment outcomes of opioid dependence with implantable and oral naltrexone in randomized double blinded double dummy placebo controlled clinical trial. Methods: 306 patients with opioid dependence were randomized in 3 treatment groups (102 ss in each). The first group received implantation of 1000 mg naltrexone every 2 months during the 6 months period + oral naltrexone placebo; the second group — placebo implant every 2 months + oral naltrexone (50mg/day),

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Ventriglio, A., A. Petito, A. Gentile, et al. "Pharmacodynamic targets of psychotic patients treated with a long-acting therapy." European Psychiatry 41, S1 (2017): S366—S367. http://dx.doi.org/10.1016/j.eurpsy.2017.02.370.

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IntroductionGiven the poor compliance of schizofrenic patients to antipsychotic therapies, are been developed drugs in long-acting formulation that for their pharmacokinetic ensures prolonged therapeutic activities. Currently, we consider that their efficacy depends on hereditary tracts, influencing both pharmacodynamic and pharmacokinetic parameters.ObjectiveInvestigate relationships between clinical efficacy and genetic polymorphims of long-acting drugs’ pharmacodynamic targets.MethodsSeventy-eight psychotic patients, treated with atypical long-acting antipsychotics (olanzapine pamoate, pali

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Dissertations / Theses on the topic "DRD2 receptors polymorphisms"

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FRoehlich, Tanya. "ADHD-related Executive Functions: Interactions of a DRD4 Polymorphism, Lead, and Sex." University of Cincinnati / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1185465160.

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Strobel, Alexander, Frank M. Spinath, Alois Angleitner, Rainer Riemann, and Klaus-Peter Lesch. "Lack of Association between Polymorphisms of the Dopamine D4 Receptor Gene and Personality." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-134660.

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Recent studies have suggested a role of two polymorphisms of the dopamine D4 receptor gene (DRD4 exon III and –521C/T) in the modulation of personality traits such as ‘novelty seeking’ or ‘extraversion’, which are supposed to be modulated by individual differences in dopaminergic function. However, several replication studies have not provided positive findings. The present study was performed to further investigate whether DRD4 exon III and –521C/T are associated with individual differences in personality. One hundred and fifteen healthy German volunteers completed the NEO-Five-Factor Invento

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Strobel, Alexander, Frank M. Spinath, Alois Angleitner, Rainer Riemann, and Klaus-Peter Lesch. "Lack of Association between Polymorphisms of the Dopamine D4 Receptor Gene and Personality." Karger, 2003. https://tud.qucosa.de/id/qucosa%3A27586.

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Recent studies have suggested a role of two polymorphisms of the dopamine D4 receptor gene (DRD4 exon III and –521C/T) in the modulation of personality traits such as ‘novelty seeking’ or ‘extraversion’, which are supposed to be modulated by individual differences in dopaminergic function. However, several replication studies have not provided positive findings. The present study was performed to further investigate whether DRD4 exon III and –521C/T are associated with individual differences in personality. One hundred and fifteen healthy German volunteers completed the NEO-Five-Factor Invento

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Djivré, Ilan-Alan. "Cognitive testing and analysis of the dopamine receptor D4 (DRD4) exon III polymorphism and CSF metabolites in male African green monkeys (Chlorocebus aethiops)." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=99335.

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A sample of 100 male vervets was appraised with the Object Retrieval Task (ORT- a test of general cognitive ability) and Time-Restricted Arousal Induction Test (TRAIT- a response performance task based on ethological observations) and genotyped for a VNTR residing in exon III of the dopamine receptor 4 (DRD4) gene. A factor analysis of the combined measurements has revealed 3 factors, accounting for 70% of the variability. They were interpreted as cognitive ability (eigenvalue=4.3), cautiousness (eigenvalue=2.1) and impulsive responding (eigenvalue=1.3). No association was found between the DR

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JANDOVÁ, Linda. "Možná asociace polymorfismů v genu pro dopaminový receptor D2 (\kur{DRD2}) s lidským chováním." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-394613.

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This study is focused on the dopamine D2 receptor and the linkage between TaqIA and - 141C Ins/Del polymorphisms in DRD2 gene and novelty seeking behaviour, as well as the linkage between Val158Met polymorphism in COMT gene and novelty seeking behaviour. Novelty seeking behaviour is characterized as a personality trait with a tendency to look for novel stimulation and extravagances at any cost of legal, physical and social risk to reward cues. DRD2 and COMT genes are associated with the function of dopamine, which is essential for motoric function and reward-motivated behaviour. Therefore, the

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Abdulnour, Shahad. "Effect of Dopamine Receptor DRD2 and ANKK1 Polymorphisms on Dietary Compliance, Blood Pressure, and BMI in Type 2 Diabetic Patients." Thesis, 2010. http://hdl.handle.net/1807/25396.

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Reduction in dopamine receptor D2, has been associated with insufficient brain reward, food addiction, obesity, and type 2 diabetes (T2D). Our aim was to assess whether the genetic variability responsible for this reduction is associated with poor dietary compliance and life style habits in T2D patients. Genetic-analysis was done for 109 T2D individuals who completed a 24-week randomized clinical trial and were assigned to follow either a low-GI or a high-fibre diet. Polymorphisms of TaqIA and C957T were compared with physical and biochemical measures. Regardless of dietary treatments, individ

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EGRIOVÁ, Simona. "Rizikové chování v závislosti na genu alela A1 pro dopaminový receptor D2." Master's thesis, 2019. http://www.nusl.cz/ntk/nusl-394873.

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The studies that have been published since 1990 which are dealing with the relationship of the genetic polymorphism of the dopamine D2 receptor gene (DRD2) in relation to alcoholism or other disorders or diseases have brought contradictory results. These results have led the author of this thesis to closely investigate the relationship between the genetic polymorphism of the A1 allele gene for DRD2 and hazardous alcohol consumption in the Czech Republic with a focus on the artistic area. A total of 29 participants (15 artists and 14 "non-artists") were involved in the study. The criterion for

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Da, Costa Laura Anne. "Genetic Modifiers of Caffeine Consumption and Risk of Myocardial Infarction." Thesis, 2011. http://hdl.handle.net/1807/29516.

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The variability in caffeine consumption and inconsistencies among studies linking caffeine to heart disease may be explained by genetic variation. Caffeine antagonizes adenosine receptors with downstream effects on dopamine and serotonin. The objectives of this thesis were to determine whether the DRD2 957C>T or HTR2A 102C>T polymorphisms are associated with caffeine consumption or modify the association between coffee consumption and risk of myocardial infarction (MI). DRD2 genotype was associated with caffeine consumption among non-smokers and CYP1A2 -163C allele carriers. HTR2A genotype was

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Book chapters on the topic "DRD2 receptors polymorphisms"

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Tomitaka, Shin-Ichiro. "Association Between Novelty Seeking and Dopamine Receptor D4 (DRD4) Exon III Polymorphism." In Contemporary Neuropsychiatry. Springer Japan, 2001. http://dx.doi.org/10.1007/978-4-431-67897-7_72.

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V. Gafarov, Valery, Elena A. Gromova, Vladimir N. Maksimov, Igor V. Gagulin, and Almira V. Gafarova. "Association of Personal Anxiety with Dopamine Receptor D4 (DRD4), DAT Genes Polymorphism." In Anxiety Disorders [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.94386.

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Modern studies in the world have attached high priority to the role of genetics in human psychosocial stress. People who have strong biochemical responses to stress are more inclined to develop acute and posttraumatic stress disorders. Why do such unusually strong biological reactions occur in certain people? Psychogenetics focuses on many aspects: personality traits that can affect human behavior directly. Their individual variability has been found to be a genetic trait. At present we already know a number of genes, certain allelic variants and genotypes associated with some neuropsychologic

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