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1

Jiang, Fangwei, Xiaofeng Xu, Hailiang Liu, and Jian Zhu. "DRM1 and DRM2 are involved in Arabidopsis callus formation." Plant Cell, Tissue and Organ Culture (PCTOC) 123, no. 2 (2015): 221–28. http://dx.doi.org/10.1007/s11240-015-0812-5.

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2

Forgione, Ivano, Magdalena Wołoszyńska, Marianna Pacenza, et al. "Hypomethylated drm1 drm2 cmt3 mutant phenotype of Arabidopsis thaliana is related to auxin pathway impairment." Plant Science 280 (March 2019): 383–96. http://dx.doi.org/10.1016/j.plantsci.2018.12.029.

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3

Rae, Georgina M., Karine David, and Marion Wood. "The Dormancy Marker DRM1/ARP Associated with Dormancy but a Broader Role In Planta." Developmental Biology Journal 2013 (June 11, 2013): 1–12. http://dx.doi.org/10.1155/2013/632524.

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Plants must carefully regulate their development in order to survive a wide range of conditions. Of particular importance to this is dormancy release, deciding when to grow and when not to, given these varying conditions. In order to better understand the growth release mechanism of dormant tissue at the molecular and physiological levels, molecular markers can be used. One gene family that has a long association with dormancy, which is routinely used as a marker for dormancy release, is DRM1/ARP (dormancy-associated gene-1/auxin-repressed protein). This plant-specific gene family has high seq
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Rae, Georgina M., Vladimir N. Uversky, Karine David, and Marion Wood. "DRM1 and DRM2 expression regulation: potential role of splice variants in response to stress and environmental factors in Arabidopsis." Molecular Genetics and Genomics 289, no. 3 (2014): 317–32. http://dx.doi.org/10.1007/s00438-013-0804-2.

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5

Tian, Wenwen, Ruyi Wang, Cunpei Bo, et al. "SDC mediates DNA methylation-controlled clock pace by interacting with ZTL in Arabidopsis." Nucleic Acids Research 49, no. 7 (2021): 3764–80. http://dx.doi.org/10.1093/nar/gkab128.

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Abstract Molecular bases of eukaryotic circadian clocks mainly rely on transcriptional-translational feedback loops (TTFLs), while epigenetic codes also play critical roles in fine-tuning circadian rhythms. However, unlike histone modification codes that play extensive and well-known roles in the regulation of circadian clocks, whether DNA methylation (5mC) can affect the circadian clock, and the associated underlying molecular mechanisms, remains largely unexplored in many organisms. Here we demonstrate that global genome DNA hypomethylation can significantly lengthen the circadian period of
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6

Tripepi, A., and L. Guglielminetti. "Actions of strigolactone GR24 and DRM1 gene expression on Arabidopsis root architecture." Russian Journal of Plant Physiology 64, no. 6 (2017): 845–49. http://dx.doi.org/10.1134/s1021443717060127.

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7

Knopf, Dominik, and Christoph Sorge. "Model-oriented analysis of user – right holder relations and possible impacts of DRM1." Information Services & Use 23, no. 4 (2003): 235–39. http://dx.doi.org/10.3233/isu-2003-23404.

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8

Yoon, Seo-Kyung, Eun-Kyung Bae, Hyunmo Choi, Young-Im Choi, and Hyoshin Lee. "Isolation and Expression of Dormancy-associated protein 1 (DRM1) in Poplar (Populus alba × P. glandulosa)." Journal of Plant Biotechnology 44, no. 1 (2017): 69–75. http://dx.doi.org/10.5010/jpb.2017.44.1.069.

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9

Yoon, Seo-Kyung, Eun-Kyung Bae, Hyunmo Choi, Young-Im Choi, and Hyoshin Lee. "Isolation and Expression of Dormancy-associated protein 1 (DRM1) in Poplar (Populus alba × P. glandulosa)." Journal of Plant Biotechnology 44, no. 3 (2017): 207. http://dx.doi.org/10.5010/jpb.2017.44.3.207.

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10

ZHU, Yong, Hui Fang ZHAO, Guo Dong REN, Xiao Fei YU, Shu Qing CAO, and Ben Ke KUAI. "Characterization of a novel developmentally retarded mutant (drm1) associated with the autonomous flowering pathway in Arabidopsis." Cell Research 15, no. 2 (2005): 133–40. http://dx.doi.org/10.1038/sj.cr.7290278.

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11

Lewsey, Mathew G., Thomas J. Hardcastle, Charles W. Melnyk, et al. "Mobile small RNAs regulate genome-wide DNA methylation." Proceedings of the National Academy of Sciences 113, no. 6 (2016): E801—E810. http://dx.doi.org/10.1073/pnas.1515072113.

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RNA silencing at the transcriptional and posttranscriptional levels regulates endogenous gene expression, controls invading transposable elements (TEs), and protects the cell against viruses. Key components of the mechanism are small RNAs (sRNAs) of 21–24 nt that guide the silencing machinery to their nucleic acid targets in a nucleotide sequence-specific manner. Transcriptional gene silencing is associated with 24-nt sRNAs and RNA-directed DNA methylation (RdDM) at cytosine residues in three DNA sequence contexts (CG, CHG, and CHH). We previously demonstrated that 24-nt sRNAs are mobile from
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12

Wood, Marion, Georgina M. Rae, Rong-Mei Wu, et al. "Actinidia DRM1 - An Intrinsically Disordered Protein Whose mRNA Expression Is Inversely Correlated with Spring Budbreak in Kiwifruit." PLoS ONE 8, no. 3 (2013): e57354. http://dx.doi.org/10.1371/journal.pone.0057354.

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13

Park, Sung-Kyu, and Goo-Man Park. "A Study on the AM/FM Digital Radio for Practical Use Based on DRM and DRM+." Journal of Broadcast Engineering 17, no. 6 (2012): 990–1003. http://dx.doi.org/10.5909/jbe.2012.17.6.990.

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14

Souza, Gilza Barcelos de, Tiago Antônio de Oliveira Mendes, Patrícia Pereira Fontes, et al. "Genome-wide identification and expression analysis of dormancy-associated gene 1/auxin repressed protein (DRM1/ARP) gene family in Glycine max." Progress in Biophysics and Molecular Biology 146 (September 2019): 134–41. http://dx.doi.org/10.1016/j.pbiomolbio.2019.03.006.

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15

Wang, Benqi, Jie Liu, Lei Chu, et al. "Exogenous Promoter Triggers APETALA3 Silencing through RNA-Directed DNA Methylation Pathway in Arabidopsis." International Journal of Molecular Sciences 20, no. 18 (2019): 4478. http://dx.doi.org/10.3390/ijms20184478.

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The development of floral organs plays a vital role in plant reproduction. In our research, the APETALA3 (AP3) promoter-transgenic lines showed abnormal developmental phenotypes in stamens and petals. The aim of this study is to understand the molecular mechanisms of the morphological defects in transgenic plants. By performing transgenic analysis, it was found that the AP3-promoted genes and the vector had no relation to the morphological defects. Then, we performed the expression analysis of the class A, B, and C genes. A dramatic reduction of transcript levels of class B genes (AP3 and PIST
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16

Jeong, Yeon-Jeong, Ki-Song Yoon, and Ho-Gab Kang. "DRM interoperable scheme by connection between heterogeneous DRM systems." KIPS Transactions:PartC 13C, no. 2 (2006): 155–60. http://dx.doi.org/10.3745/kipstc.2006.13c.2.155.

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17

Perrier, P., C. Reveillère, and A. Schuhmacher. "A new DRB1 allele (DRB1*1125) sharing DR11 and DR8 sequence motifs." Tissue Antigens 49, no. 1 (1997): 84–87. http://dx.doi.org/10.1111/j.1399-0039.1997.tb02717.x.

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18

Lin, Dan, Lei Tian, Shu Zhang, Like Wang, Ying Jie, and Yongjin Zhou. "Keratoconus Diagnosis: Validation of a Novel Parameter Set Derived from IOP-Matched Scenario." Journal of Ophthalmology 2020 (October 28, 2020): 1–6. http://dx.doi.org/10.1155/2020/6530279.

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Purpose. Considering that intraocular pressure (IOP) is an important confounding factor in corneal biomechanical evaluation, the notion of matching IOP should be introduced to eliminate any potential bias. This study aimed to assess the capability of a novel parameter set (NPS) derived from IOP-matched scenario to diagnose keratoconus. Methods. Seventy samples (training set; 35 keratoconus and 35 normal corneas; pairwise matching for IOP) were used to determine NPS by forward logistic regression. A large validation dataset comprising 62 matching samples (31 keratoconus and 31 normal corneas) a
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19

Zhong, Xuehua, Christopher J. Hale, Minh Nguyen, et al. "DOMAINS REARRANGED METHYLTRANSFERASE3 controls DNA methylation and regulates RNA polymerase V transcript abundance in Arabidopsis." Proceedings of the National Academy of Sciences 112, no. 3 (2015): 911–16. http://dx.doi.org/10.1073/pnas.1423603112.

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DNA methylation is a mechanism of epigenetic gene regulation and genome defense conserved in many eukaryotic organisms. In Arabidopsis, the DNA methyltransferase DOMAINS REARRANGED METHYLASE 2 (DRM2) controls RNA-directed DNA methylation in a pathway that also involves the plant-specific RNA Polymerase V (Pol V). Additionally, the Arabidopsis genome encodes an evolutionarily conserved but catalytically inactive DNA methyltransferase, DRM3. Here, we show that DRM3 has moderate effects on global DNA methylation and small RNA abundance and that DRM3 physically interacts with Pol V. In Arabidopsis
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20

Pawelec, G., H. Max, T. Halder, et al. "BCR/ABL leukemia oncogene fusion peptides selectively bind to certain HLA-DR alleles and can be recognized by T cells found at low frequency in the repertoire of normal donors." Blood 88, no. 6 (1996): 2118–24. http://dx.doi.org/10.1182/blood.v88.6.2118.bloodjournal8862118.

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Chronic myelogenous leukemia (CML) is characterized by the t(9;22) translocation that results in chimeric genes encoding bcr/abl fusion proteins. Junction-spanning sequences represent unique tumor-specific moieties that might be exploited therapeutically. We investigate here the binding of synthetic bcr/abl peptides to various HLA-DR alleles and their recognition by T cells from normal donors and CML patients. A 23- mer b3/a2 peptide bound very strongly to isolated HLA-DRB1*1101 (Dw5) and relatively strongly to DRB1*0301 (Dw3) and DRB1*0402 (Dw10) molecules, as estimated using a competition as
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21

Bannai, Makoto, Katsushi Tokunaga, Ling Lin, et al. "A new HLA-DR11 DRB1 allele found in a Korean." Human Immunology 39, no. 3 (1994): 230–32. http://dx.doi.org/10.1016/0198-8859(94)90265-8.

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22

Gilardin, Laurent, Sandrine Delignat, Bernard Maillere, et al. "Identification of T Cell Epitope of ADAMTS13 in Thrombotic Thrombocytopenic Purpura Patients." Blood 126, no. 23 (2015): 106. http://dx.doi.org/10.1182/blood.v126.23.106.106.

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Abstract Introduction: Thrombotic Thrombocytopenic Purpura (TTP) results from the development of auto-antibodies directed against A Disintegrin And Metalloproteinase with Thrombospondin type 1 repeats, 13th member (A13). The implication of CD4+ T-cells in the pathogenesis of the disease is suggested by the existence of a restriction to HLA DRB1*11 allele and by the isotype switch of the antibodies. However, T-cell autoimmune response to A13 and the properties of CD4+ T-cells from TTP patients have never been studied. Here, we determined the immunodominant T-cell epitope of A13 in TTP patients.
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23

Ricafort, R. J., M. Stephan, R. O’Reilly, and M. Sadelain. "In vitro expansion of CMV-specific CD4+ T-cells by artificial antigen presentation for adoptive immunotherapy in the post- transplant setting." Journal of Clinical Oncology 25, no. 18_suppl (2007): 3049. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.3049.

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3049 Background: CMV continues to be a major cause of morbidity and mortality in marrow allograft recipients. The importance of CD4+ T-cells in maintaining immunity and therapeutic efficacy in adoptive cellular strategies has been appreciated. With a novel artificial antigen presenting cell (AAPC) system, we induced the expansion of CMV-specific CD4+ T-cells. Methods: AAPCs were generated by using a standardizable line of murine 3T3 cells sequentially transduced to express human ICAM-1, LFA-1, B7.1, HLA A*0201 and DRB1*1101 alleles. Antigen was provided either by peptide pulsing with the HLA-D
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24

Bidwell, J. L., and E. A. Bidwell. "DISCRIMINATION BETWEEN HLA-DR1 (DRB1*0101) AND DR'Br'(DRB1*0103) USING SEQUENCE-SPECIFIC OLIGONUCLEOTIDE PROBES." European Journal of Immunogenetics 18, no. 1-2 (1991): 105–9. http://dx.doi.org/10.1111/j.1744-313x.1991.tb00010.x.

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25

Thonnard, J., B. Blaimond, M. Heusterspreut, N. Straetmans, and M. Philippe. "A new HLA-DRB1*1116 allele sharing DR13 and DR11 sequence motifs." Tissue Antigens 46, no. 2 (1995): 124–27. http://dx.doi.org/10.1111/j.1399-0039.1995.tb02488.x.

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26

Loh, M. T., S. H. Chan, and E. C. Ren. "A monoclonal antibody with specificity to the HLA-DR1 and -DR51 antigens." Tissue Antigens 42, no. 1 (1993): 100–104. http://dx.doi.org/10.1111/j.1399-0039.1993.tb02174.x.

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27

Loh, M. T., S. H. Chan, and E. C. Ren. "A monoclonal antibody with specflicity to the HLA-DR1 and -DR51 antigens." Tissue Antigens 42, no. 2 (1993): 100–104. http://dx.doi.org/10.1111/j.1399-0039.1993.tb02244.x.

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28

Carcassi, C., L. Floris, F. Cottoni, et al. "Molecular analysis of HLA-DRB1-DR1 associated alleles in lichen ruber planus." Human Immunology 36, no. 1 (1993): 51. http://dx.doi.org/10.1016/0198-8859(93)90041-x.

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29

Vries, Niek, Kjersti S. Renningen, Marcel G. J. Tilanus, et al. "HLA-DR1 and rheumatoid arthntis in Israeli Jews: Sequencing reveals that DRB1*0102 is the predominant HLA-DR1 subtype." Tissue Antigens 41, no. 1 (1993): 26–30. http://dx.doi.org/10.1111/j.1399-0039.1993.tb01973.x.

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30

Smith, Anajane G., Effie W. Petersdorf, Eric Mickelson, et al. "HLA-DRB1 frrst domain sequences of two new DR11 alleles and one novel DR4 allele." Tissue Antigens 42, no. 5 (1993): 533–35. http://dx.doi.org/10.1111/j.1399-0039.1993.tb02200.x.

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31

Canossi, A., D. Piancatelli, F. Papola, et al. "Sequence analysis of a new HLA-DR11 allele in a Caucasian Italian family: DRB1*11272." Tissue Antigens 56, no. 5 (2000): 470–72. http://dx.doi.org/10.1034/j.1399-0039.2000.560515.x.

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32

Laforet, Michel, Arlette Urlacher, Annie Falkenrodt, Bruno Lioure, Anne Parissiadis, and Marie M. Tongio. "A new DR14 allele (DRB1∗1411) containing a short DR11 sequence and its haplotypic association." Human Immunology 36, no. 3 (1993): 179–85. http://dx.doi.org/10.1016/0198-8859(93)90123-i.

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33

Rosloniec, Edward F., Karen B. Whittington, Dennis M. Zaller, and Andrew H. Kang. "HLA-DR1 (DRB1*0101) and DR4 (DRB1*0401) Use the Same Anchor Residues for Binding an Immunodominant Peptide Derived from Human Type II Collagen." Journal of Immunology 168, no. 1 (2002): 253–59. http://dx.doi.org/10.4049/jimmunol.168.1.253.

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34

Alvarez, Iñaki, Javier Collado, Xavier Daura, et al. "The rheumatoid arthritis-associated allele HLA-DR10 (DRB1*1001) shares part of its repertoire with HLA-DR1 (DRB1*0101) and HLA-DR4 (DRB*0401)." Arthritis & Rheumatism 58, no. 6 (2008): 1630–39. http://dx.doi.org/10.1002/art.23503.

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35

Trejaut, J., D. Hobart, A. Kennedy, W. D. Greville, A. Taverniti, and H. Dunckley. "New DRB1* alleles (HLA-DRB1*1135, DRB1*1430 and DRB1*1433) and a confirmatory sequence (DRB1*1133)." Tissue Antigens 55, no. 1 (2000): 89–91. http://dx.doi.org/10.1034/j.1399-0039.2000.550120.x.

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36

Woo, Yongje, Mingoo Kang, and Jeongwook Seo. "Multiplex Distribution Interface Analyzer Using Memory Sharing Techniqyes on Ethernet Mode for DRM/DRM+ Systems." Journal of Internet Computing and Services 15, no. 2 (2014): 143–47. http://dx.doi.org/10.7472/jksii.2014.15.2.143.

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37

Sorvillo, Nicoletta, Simon D. van Haren, Wouter Pos, et al. "C-Type Lectin Receptor Mediated Immune Recognition of ADAMTS13 Promotes HLA-DRB1*11 Dependent Presentation of CUB1-2 Derived Peptides by Dendritic Cells." Blood 118, no. 21 (2011): 196. http://dx.doi.org/10.1182/blood.v118.21.196.196.

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Abstract Abstract 196 ADAMTS13 is a plasma metalloproteinase that regulates platelet adhesion and aggregation by virtue of its ability to process newly released ultra-large von Willebrand factor (VWF) multimers on the surface of endothelial cells. Autoantibodies directed against ADAMTS13 prohibit the processing of VWF multimers initiating a rare and life-threatening disorder called acquired thrombotic thrombocytopenic purpura (TTP). HLA-DRB1*11 has recently been identified as a risk factor for acquired TTP. This finding implies that formation of autoantibodies towards ADAMTS13 depends on appro
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38

Buyse, I. M., C. Couture, and S. Hasheml-Tavoularis. "Identification of novel DRB1*11 (DRB1*11013, DRB1*1129), DRB1*08 (DRB1*0816) and DRB5* (DRB5*0107) alleles." Tissue Antigens 50, no. 6 (1997): 678–81. http://dx.doi.org/10.1111/j.1399-0039.1997.tb02933.x.

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39

Middleton, D., D. J. Hughes, F. Williams, C. A. Graham, J. Martin, and D. A. Savage. "A new DRB1 allele DRB1*1107 - a combination of DRB1*11 and DRB1*03." Tissue Antigens 42, no. 1 (1993): 160–63. http://dx.doi.org/10.1111/j.1399-0039.1993.tb02187.x.

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40

Lin, Y. S., R. J. Hoyer, T. F. Tang, J. Ng, R. J. Hartzman, and C. K. Hurley. "Detection of four novel alleles: DRB1*1130, DRB1*13072, DRB1*1315 and DRB1*1331." Tissue Antigens 55, no. 1 (2000): 92–96. http://dx.doi.org/10.1034/j.1399-0039.2000.550121.x.

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41

Gulgnler, F., F. Dufossé, P. Cracco, C. Krausé, and C. Coffe. "A novel variant of DR11 (DRB1*1128) identified in the family by polymerase chain reaction-reverse dot blot." Tissue Antigens 50, no. 1 (1997): 94–95. http://dx.doi.org/10.1111/j.1399-0039.1997.tb02844.x.

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42

Greville, W. D., G. Chapman, J.-P. Hogbin, A. Kennedy, and H. Dunckley. "Novel HLA-DRB1 alleles discovered during routine sequencing based typing, DRB1*03052, DRB1*04032, DRB1*1139 and DRB1*1346." Tissue Antigens 59, no. 2 (2002): 154–56. http://dx.doi.org/10.1034/j.1399-0039.2002.590217.x.

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43

Taochy, Christelle, Agnès Yu, Nicolas Bouché, et al. "Post-transcriptional gene silencing triggers dispensable DNA methylation in gene body in Arabidopsis." Nucleic Acids Research 47, no. 17 (2019): 9104–14. http://dx.doi.org/10.1093/nar/gkz636.

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Abstract Spontaneous post-transcriptional silencing of sense transgenes (S-PTGS) is established in each generation and is accompanied by DNA methylation, but the pathway of PTGS-dependent DNA methylation is unknown and so is its role. Here we show that CHH and CHG methylation coincides spatially and temporally with RDR6-dependent products derived from the central and 3′ regions of the coding sequence, and requires the components of the RNA-directed DNA methylation (RdDM) pathway NRPE1, DRD1 and DRM2, but not CLSY1, NRPD1, RDR2 or DCL3, suggesting that RDR6-dependent products, namely long dsRNA
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44

Tréjaut, J., A. Kennedy, D. Hobart, et al. "PCR-RFLP typing detects new HLA-DRB1 alleles: DRB1*13022, DRB1*1336 and DRB1*1435." European Journal of Immunogenetics 28, no. 4 (2001): 441–47. http://dx.doi.org/10.1046/j.1365-2370.2001.00243.x.

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45

Hashemi, S., C. Couture, I. Buyse, R. Cole, and M. T. Aye. "Sequence analysis of three novel HLA-DRB1 alleles: DRB1*1113, DRB1*1114 and DRB1*12032." Tissue Antigens 47, no. 2 (1996): 155–58. http://dx.doi.org/10.1111/j.1399-0039.1996.tb02532.x.

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46

Shaker, Olfat, Heba Bassiony, Maissa El Raziky, et al. "Human Leukocyte Antigen Class II Alleles (DQB1 and DRB1) as Predictors for Response to Interferon Therapy in HCV Genotype 4." Mediators of Inflammation 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/392746.

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Human leukocyte antigens class II play an important role in immune response against HCV. We investigated whether HLA class II alleles influence susceptibility to HCV infection and response to interferon therapy. HLA-DRB1 and -DQB1 loci were genotyped using PCR-SSO Luminex technology. According to our regimen, 41 (66%) of patients achieved sustained virological response to combined treatment of IFN and ribavirin. Frequencies of DQB1*0313 allele and DRB1*04-DRB1*11, DQB1*0204-DQB1*0313, DQB1*0309-DQB1*0313, and DQB1*0313-DQB1*0319 haplotypes were significantly more frequent in nonresponders than
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47

Qu, J. H., J. Li, H. Chen, Z. Z. Zheng, K. Z. Liao, and M. Z. Shen. "Identification of nine novel HLA-DRB1 alleles, HLA-DRB1*04:91, DRB1*07:18, DRB1*11:01:12, DRB1*12:02:05, DRB1*12:22, DRB1*12:23, DRB1*13:100, DRB1*15:45, and DRB1*15:46 by polymerase chain reaction-sequence-based typing." Tissue Antigens 77, no. 3 (2011): 264–66. http://dx.doi.org/10.1111/j.1399-0039.2010.01609.x.

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48

Asu, U., M. Taylor, D. Dunn, J. B. Hunter, and T. C. Fuller. "A new DRB1 allele: DRB1∗ 03NEW." Human Immunology 40 (January 1994): 36. http://dx.doi.org/10.1016/0198-8859(94)91731-0.

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49

Liu, Raymond, and David C. Chan. "The mitochondrial fission receptor Mff selectively recruits oligomerized Drp1." Molecular Biology of the Cell 26, no. 24 (2015): 4466–77. http://dx.doi.org/10.1091/mbc.e15-08-0591.

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Dynamin-related protein 1 (Drp1) is the GTP-hydrolyzing mechanoenzyme that catalyzes mitochondrial fission in the cell. Residing in the cytosol as dimers and tetramers, Drp1 is recruited by receptors on the mitochondrial outer membrane, where it further assembles into a helical ring that drives division via GTP-dependent constriction. The Drp1 receptor Mff is a major regulator of mitochondrial fission, and its overexpression results in increased fission. In contrast, the alternative Drp1 receptors MiD51 and MiD49 appear to recruit inactive forms of Drp1, because their overexpression inhibits f
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50

Duran, Karen J., Hiroo Maeda, Henny G. Otten, Rene De Vries, Geziena M. T. Schreuder, and M. G. J. Tilanus. "Two newly identified HLA-DRB1 alleles: DRB1 * 1322 and DRB1 * 1327." Immunogenetics 46, no. 5 (1997): 442–43. http://dx.doi.org/10.1007/s002510050302.

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