Log in

Relevant bibliographies by topics / Drosophila Drosophila Drosophila Infertility, Male / Journal articles

To see the other types of publications on this topic, follow the link: Drosophila Drosophila Drosophila Infertility, Male.

Journal articles on the topic 'Drosophila Drosophila Drosophila Infertility, Male'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Drosophila Drosophila Drosophila Infertility, Male.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Wu, Hao, Liwei Sun, Yang Wen, Yujuan Liu, Jun Yu, Feiyu Mao, Ya Wang, et al. "Major spliceosome defects cause male infertility and are associated with nonobstructive azoospermia in humans." Proceedings of the National Academy of Sciences 113, no. 15 (March 28, 2016): 4134–39. http://dx.doi.org/10.1073/pnas.1513682113.

Full text

Abstract:

Processing of pre-mRNA into mRNA is an important regulatory mechanism in eukaryotes that is mediated by the spliceosome, a huge and dynamic ribonucleoprotein complex. Splicing defects are implicated in a spectrum of human disease, but the underlying mechanistic links remain largely unresolved. Using a genome-wide association approach, we have recently identified single nucleotide polymorphisms in humans that associate with nonobstructive azoospermia (NOA), a common cause of male infertility. Here, using genetic manipulation of corresponding candidate loci in Drosophila, we show that the spliceosome component SNRPA1/U2A is essential for male fertility. Loss of U2A in germ cells of the Drosophila testis does not affect germline stem cells, but does result in the accumulation of mitotic spermatogonia that fail to differentiate into spermatocytes and mature sperm. Lack of U2A causes insufficient splicing of mRNAs required for the transition of germ cells from proliferation to differentiation. We show that germ cell-specific disruption of other components of the major spliceosome manifests with the same phenotype, demonstrating that mRNA processing is required for the differentiation of spermatogonia. This requirement is conserved, and expression of human SNRPA1 fully restores spermatogenesis in U2A mutant flies. We further report that several missense mutations in human SNRPA1 that inhibit the assembly of the major spliceosome dominantly disrupt spermatogonial differentiation in Drosophila. Collectively, our findings uncover a conserved and specific requirement for the major spliceosome during the transition from spermatogonial proliferation to differentiation in the male testis, suggesting that spliceosome defects affecting the differentiation of human spermatogonia contribute to NOA.

APA, Harvard, Vancouver, ISO, and other styles

2

Morton, David B., Rachel Clemens-Grisham, Dennis J. Hazelett, and Anke Vermehren-Schmaedick. "Infertility and Male Mating Behavior Deficits Associated With Pde1c in Drosophila melanogaster." Genetics 186, no. 1 (June 15, 2010): 159–65. http://dx.doi.org/10.1534/genetics.110.118018.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Siddall, N. A., and G. R. Hime. "A Drosophila toolkit for defining gene function in spermatogenesis." Reproduction 153, no. 4 (April 2017): R121—R132. http://dx.doi.org/10.1530/rep-16-0347.

Full text

Abstract:

Expression profiling and genomic sequencing methods enable the accumulation of vast quantities of data that relate to the expression of genes during the maturation of male germ cells from primordial germ cells to spermatozoa and potential mutations that underlie male infertility. However, the determination of gene function in specific aspects of spermatogenesis or linking abnormal gene function with infertility remain rate limiting, as even in an era of CRISPR analysis of gene function in mammalian models, this still requires considerable resources and time. Comparative developmental biology studies have shown the remarkable conservation of spermatogenic developmental processes from insects to vertebrates and provide an avenue of rapid assessment of gene function to inform the potential roles of specific genes in rodent and human spermatogenesis. The vinegar fly, Drosophila melanogaster, has been used as a model organism for developmental genetic studies for over one hundred years, and research with this organism produced seminal findings such as the association of genes with chromosomes, the chromosomal basis for sexual identity, the mutagenic properties of X-irradiation and the isolation of the first tumour suppressor mutations. Drosophila researchers have developed an impressive array of sophisticated genetic techniques for analysis of gene function and genetic interactions. This review focuses on how these techniques can be utilised to study spermatogenesis in an organism with a generation time of 9 days and the capacity to introduce multiple mutant alleles into an individual organism in a relatively short time frame.

APA, Harvard, Vancouver, ISO, and other styles

4

Tao, Yun, Zhao-Bang Zeng, Jian Li, Daniel L. Hartl, and Cathy C. Laurie. "Genetic Dissection of Hybrid Incompatibilities BetweenDrosophila simulansandD. mauritiana. II. Mapping Hybrid Male Sterility Loci on the Third Chromosome." Genetics 164, no. 4 (August 1, 2003): 1399–418. http://dx.doi.org/10.1093/genetics/164.4.1399.

Full text

Abstract:

AbstractHybrid male sterility (HMS) is a rapidly evolving mechanism of reproductive isolation in Drosophila. Here we report a genetic analysis of HMS in third-chromosome segments of Drosophila mauritiana that were introgressed into a D. simulans background. Qualitative genetic mapping was used to localize 10 loci on 3R and a quantitative trait locus (QTL) procedure (multiple-interval mapping) was used to identify 19 loci on the entire chromosome. These genetic incompatibilities often show dominance and complex patterns of epistasis. Most of the HMS loci have relatively small effects and generally at least two or three of them are required to produce complete sterility. Only one small region of the third chromosome of D. mauritiana by itself causes a high level of infertility when introgressed into D. simulans. By comparison with previous studies of the X chromsome, we infer that HMS loci are only ∼40% as dense on this autosome as they are on the X chromosome. These results are consistent with the gradual evolution of hybrid incompatibilities as a by-product of genetic divergence in allopatric populations.

APA, Harvard, Vancouver, ISO, and other styles

5

Chow, Clement Y., Frank W. Avila, Andrew G. Clark, and Mariana F. Wolfner. "Induction of Excessive Endoplasmic Reticulum Stress in the Drosophila Male Accessory Gland Results in Infertility." PLOS ONE 10, no. 3 (March 5, 2015): e0119386. http://dx.doi.org/10.1371/journal.pone.0119386.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Camper, Sally A., Michelle L. Brinkmeier, Krista A. Geister, Morgan Jones, and Ivan Maillard. "Mice Deficient in a Drosophila Homeotic Selector Ortholog Exhibit Female Infertility and Reduced Male Fertility." Biology of Reproduction 83, Suppl_1 (November 1, 2010): 313. http://dx.doi.org/10.1093/biolreprod/83.s1.313.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Lin, T. Y., S. Viswanathan, C. Wood, P. G. Wilson, N. Wolf, and M. T. Fuller. "Coordinate developmental control of the meiotic cell cycle and spermatid differentiation in Drosophila males." Development 122, no. 4 (April 1, 1996): 1331–41. http://dx.doi.org/10.1242/dev.122.4.1331.

Full text

Abstract:

Wild-type function of four Drosophila genes, spermatocyte arrest, cannonball, always early and meiosis I arrest, is required both for cell-cycle progression through the G2/M transition of meiosis I in males and for onset of spermatid differentiation. In males mutant for any one of these meiotic arrest genes, mature primary spermatocytes with partially condensed chromosomes accumulate and postmeiotic cells are lacking. The arrest in cell-cycle progression occurs prior to degradation of cyclin A protein. The block in spermatogenesis in these mutants is not simply a secondary consequence of meiotic cell-cycle arrest, as spermatid differentiation proceeds in males mutant for the cell cycle activating phosphatase twine. Instead, the arrest of both meiosis and spermiogenesis suggests a control point that may serve to coordinate the male meiotic cell cycle with the spermatid differentiation program. The phenotype of the Drosophila meiotic arrest mutants is strikingly similar to the histopathological features of meiosis I maturation arrest infertility in human males, suggesting that the control point may be conserved from flies to man.

APA, Harvard, Vancouver, ISO, and other styles

8

Zouros, E. "Advances in the genetics of reproductive isolation in Drosophila." Genome 31, no. 1 (January 1, 1989): 211–20. http://dx.doi.org/10.1139/g89-036.

Full text

Abstract:

Speciation genetics is defined as the study of genetic events and processes that differentiate the probabilities that genetic material from individual members of a population will co-occur in individuals of some future generation. It follows that phenotypic attributes that contribute to this differentiation of probabilities (e.g., mating preferences, sterility, or infertility of individuals from certain types of matings) constitute the phenotype of speciation, and genetic loci that may affect these phenotypic attributes can be considered as speciation genes. The literature on genetic differences between hybridizable species of Drosophila that are responsible for morphological differences, mating preferences, hybrid inviability, and hybrid sterility are reviewed with special reference to the species pair D. mojavensis – D. arizonensis. The case for the involvement of karyotypic changes in speciation in rodents is briefly discussed. It is concluded that no major advance has been made in the speciation genetics of Drosophila since Dobzhansky initiated the field 40 years ago. Yet, the identification of several gene loci that cause hybrid inviability or sterility may open the way to the understanding of reproductive isolation at the molecular level. It is not clear whether this approach will lead to general molecular mechanisms underlying the speciation process.Key words: speciation genetics, hybrid sterility, reproductive isolation, Drosophila.

APA, Harvard, Vancouver, ISO, and other styles

9

NOOR, MOHAMED A. F. "Patterns of evolution of genes disrupted in expression in Drosophila species hybrids." Genetical Research 85, no. 2 (April 2005): 119–25. http://dx.doi.org/10.1017/s0016672305007500.

Full text

Abstract:

Divergence between species in regulatory pathways may contribute to hybrid incompatibilities such as sterility. Consistent with this idea, genes involved in male fertility often evolve faster than most other genes both in amino acid sequence and in expression. Previously, we identified a panel of male-specific genes underexpressed in sterile male hybrids of Drosophila simulans and D. mauritiana relative to pure species, and we showed that this underexpression is associated with infertility. In a preliminary effort to assess the generalities in the patterns of evolution of these genes, I examined patterns of mRNA expression in three of these genes in sterile F1 hybrid males of D. pseudoobscura and D. persimilis. F1 hybrid males bearing D. persimilis X chromosomes underexpressed all these genes relative to the parental species, while hybrids bearing D. pseudoobscura X chromosomes underexpressed two of these three genes. Interestingly, the third gene, CG5762, has undergone extensive amino acid evolution within the D. pseudoobscura species group, possibly driven by positive natural selection. We conclude that some of the same genes exhibit disruptions in expression within each of the two species groups, which could suggest commonalities in the regulatory architecture of sterility in these groups. Alternative explanations are also considered.

APA, Harvard, Vancouver, ISO, and other styles

10

Mason, D. Adam, Robert J. Fleming, and David S. Goldfarb. "Drosophila melanogaster Importin α1 and α3 Can Replace Importin α2 During Spermatogenesis but Not Oogenesis." Genetics 161, no. 1 (May 1, 2002): 157–70. http://dx.doi.org/10.1093/genetics/161.1.157.

Full text

Abstract:

Abstract Importin α’s mediate the nuclear transport of many classical nuclear localization signal (cNLS)-containing proteins. Multicellular animals contain multiple importin α genes, most of which fall into three conventional phylogenetic clades, here designated α1, α2, and α3. Using degenerate PCR we cloned Drosophila melanogaster importin α1, α2, and α3 genes, demonstrating that the complete conventional importin α gene family arose prior to the split between invertebrates and vertebrates. We have begun to analyze the genetic interactions among conventional importin α genes by studying their capacity to rescue the male and female sterility of importin α2 null flies. The sterility of α2 null males was rescued to similar extents by importin α1, α2, and α3 transgenes, suggesting that all three conventional importin α’s are capable of performing the important role of importin α2 during spermatogenesis. In contrast, sterility of α2 null females was rescued only by importin α2 transgenes, suggesting that it plays a paralog-specific role in oogenesis. Female infertility was also rescued by a mutant importin α2 transgene lacking a site that is normally phosphorylated in ovaries. These rescue experiments suggest that male and female gametogenesis have distinct requirements for importin α2.

APA, Harvard, Vancouver, ISO, and other styles

11

Sutter, Andreas, Laura M. Travers, Keiko Oku, Kynan L. Delaney, Stefan J. Store, Tom A. R. Price, and Nina Wedell. "Flexible polyandry in female flies is an adaptive response to infertile males." Behavioral Ecology 30, no. 6 (August 21, 2019): 1715–24. http://dx.doi.org/10.1093/beheco/arz140.

Full text

Abstract:

Abstract Infertility is common in nature despite its obvious cost to individual fitness. Rising global temperatures are predicted to decrease fertility, and male sterility is frequently used in attempts to regulate pest or disease vector populations. When males are infertile, females may mate with multiple males to ensure fertilization, and changes in female mating behavior in turn could intensify selection on male fertility. Fertility assurance is a potentially wide-spread explanation for polyandry, but whether and how it actually contributes to the evolution of polyandry is not clear. Moreover, whether a drop in male fertility would lead to a genetic increase in polyandry depends on whether females respond genetically or through behavioral plasticity to male infertility. Here, we experimentally manipulate male fertility through heat-exposure in Drosophila pseudoobscura, and test female discrimination against infertile males before and after mating. Using isogenic lines, we compare the roles of behaviorally plastic versus genetically fixed polyandry. We find that heat-exposed males are less active and attractive, and that females are more likely to remate after mating with these males. Remating rate increases with reduced reproductive output, indicating that females use current sperm storage threshold to make dynamic remating decisions. After remating with fertile males, females restore normal fecundity levels. Our results suggest that male infertility could explain the evolution of adaptively flexible polyandry, but is less likely to cause an increase in genetic polyandry.

APA, Harvard, Vancouver, ISO, and other styles

12

Wang, Yu-Jia, Eko Mugiyanto, Yun-Ting Peng, Wan-Chen Huang, Wan-Hsuan Chou, Chi-Chiu Lee, Yu-Shiuan Wang, et al. "Genetic Association of the Functional WDR4 Gene in Male Fertility." Journal of Personalized Medicine 11, no. 8 (July 30, 2021): 760. http://dx.doi.org/10.3390/jpm11080760.

Full text

Abstract:

Infertility is one of the important problems in the modern world. Male infertility is characterized by several clinical manifestations, including low sperm production (oligozoospermia), reduced sperm motility (asthenozoospermia), and abnormal sperm morphology (teratozoospermia). WDR4, known as Wuho, controls fertility in Drosophila. However, it is unclear whether WDR4 is associated with clinical manifestations of male fertility in human. Here, we attempted to determine the physiological functions of WDR4 gene. Two cohorts were applied to address this question. The first cohort was the general population from Taiwan Biobank. Genomic profiles from 68,948 individuals and 87 common physiological traits were applied for phenome-wide association studies (PheWAS). The second cohort comprised patients with male infertility from Wan Fang Hospital, Taipei Medical University. In total, 81 male participants were recruited for the genetic association study. Clinical records including gender, age, total testosterone, follicle-stimulating hormone (FSH), luteinizing hormone (LH), total sperm number, sperm motility, and sperm morphology were collected. In the first cohort, results from PheWAS exhibited no associations between WDR4 genetic variants and 87 common physiological traits. In the second cohort, a total of four tagging single-nucleotide polymorphisms (tSNPs) from WDR4 gene (rs2298666, rs465663, rs2248490, and rs3746939) were selected for genotyping. We found that SNP rs465663 solely associated with asthenozoospermia. Functional annotations through the GTEx portal revealed the correlation between TT or TC genotype and low expression of WDR4. Furthermore, we used mouse embryonic fibroblasts cells from mwdr4 heterozygous (+/‒) mice for functional validation by western blotting. Indeed, low expression of WDR4 contributed to ROS-induced DNA fragmentation. In conclusion, our results suggest a critical role of WDR4 gene variant as well as protein expression in asthenozoospermia.

APA, Harvard, Vancouver, ISO, and other styles

13

Turnell, Biz R., and Klaus Reinhardt. "Metabolic Rate and Oxygen Radical Levels Increase But Radical Generation Rate Decreases with Male Age in Drosophila melanogaster Sperm." Journals of Gerontology: Series A 75, no. 12 (April 8, 2020): 2278–85. http://dx.doi.org/10.1093/gerona/glaa078.

Full text

Abstract:

Abstract Oxidative damage increases with age in a variety of cell types, including sperm, which are particularly susceptible to attack by reactive oxygen species (ROS). While mitochondrial respiration is the main source of cellular ROS, the relationship between the rates of aerobic metabolism and ROS production, and how this relationship may be affected by age, both in sperm and in other cell types, is unclear. Here, we investigate in Drosophila melanogaster sperm, the effects of male age on (i) the level of hydrogen peroxide in the mitochondria, using a transgenic H2O2 reporter line; (ii) the in situ rate of non-H2O2 ROS production, using a novel biophysical method; and (iii) metabolic rate, using fluorescent lifetime imaging microscopy. Sperm from older males had higher mitochondrial ROS levels and a higher metabolic rate but produced ROS at a lower rate. In comparison, a somatic tissue, the gut epithelium, also showed an age-related increase in mitochondrial ROS levels but a decrease in metabolic rate. These results support the idea of a tissue-specific optimal rate of aerobic respiration balancing the production and removal of ROS, with aging causing a shift away from this optimum and leading to increased ROS accumulation. Our findings also support the view that pathways of germline and somatic aging can be uncoupled, which may have implications for male infertility treatments.

APA, Harvard, Vancouver, ISO, and other styles

14

Kishi, Kasane, Aya Uchida, Hinako M. Takase, Hitomi Suzuki, Masamichi Kurohmaru, Naoki Tsunekawa, Masami Kanai-Azuma, Stephen A. Wood, and Yoshiakira Kanai. "Spermatogonial deubiquitinase USP9X is essential for proper spermatogenesis in mice." Reproduction 154, no. 2 (August 2017): 135–43. http://dx.doi.org/10.1530/rep-17-0184.

Full text

Abstract:

USP9X (ubiquitin-specific peptidase 9, X chromosome) is the mammalian orthologue of Drosophila deubiquitinase fat facets that was previously shown to regulate the maintenance of the germ cell lineage partially through stabilizing Vasa, one of the widely conserved factors crucial for gametogenesis. Here, we demonstrate that USP9X is expressed in the gonocytes and spermatogonia in mouse testes from newborn to adult stages. By using Vasa-Cre mice, germ cell-specific conditional deletion of Usp9x from the embryonic stage showed no abnormality in the developing testes by 1 week and no appreciable defects in the undifferentiated and differentiating spermatogonia at postnatal and adult stages. Interestingly, after 2 weeks, Usp9x-null spermatogenic cells underwent apoptotic cell death at the early spermatocyte stage, and then, caused subsequent aberrant spermiogenesis, which resulted in a complete infertility of Usp9x conditional knockout male mice. These data provide the first evidence of the crucial role of the spermatogonial USP9X during transition from the mitotic to meiotic phases and/or maintenance of early meiotic phase in Usp9x conditional knockout testes.

APA, Harvard, Vancouver, ISO, and other styles

15

Houston, Brendan J., Manon S. Oud, Daniel M. Aguirre, D. Jo Merriner, Anne E. O’Connor, Ozlem Okutman, Stéphane Viville, Richard Burke, Joris A. Veltman, and Moira K. O’Bryan. "Programmed Cell Death 2-Like (Pdcd2l) Is Required for Mouse Embryonic Development." G3: Genes|Genomes|Genetics 10, no. 12 (October 14, 2020): 4449–57. http://dx.doi.org/10.1534/g3.120.401714.

Full text

Abstract:

Globozoospermia is a rare form of male infertility where men produce round-headed sperm that are incapable of fertilizing an oocyte naturally. In a previous study where we undertook a whole exome screen to define novel genetic causes of globozoospermia, we identified homozygous mutations in the gene PDCD2L. Two brothers carried a p.(Leu225Val) variant predicted to introduce a novel splice donor site, thus presenting PDCD2L as a potential regulator of male fertility. In this study, we generated a Pdcd2l knockout mouse to test its role in male fertility. Contrary to the phenotype predicted from its testis-enriched expression pattern, Pdcd2l null mice died during embryogenesis. Specifically, we identified that Pdcd2l is essential for post-implantation embryonic development. Pdcd2l−/− embryos were resorbed at embryonic days 12.5-17.5 and no knockout pups were born, while adult heterozygous Pdcd2l males had comparable fertility to wildtype males. To specifically investigate the role of PDCD2L in germ cells, we employed Drosophila melanogaster as a model system. Consistent with the mouse data, global knockdown of trus, the fly ortholog of PDCD2L, resulted in lethality in flies at the third instar larval stage. However, germ cell-specific knockdown with two germ cell drivers did not affect male fertility. Collectively, these data suggest that PDCD2L is not essential for male fertility. By contrast, our results demonstrate an evolutionarily conserved role of PDCD2L in development.

APA, Harvard, Vancouver, ISO, and other styles

16

Singh, Roshni, and Bashisth Narayan Singh. "Evidence for Initiation of Post-Zygotic Reproductive Isolation between Drosophila ananassae and D. pallidosa as Indicated by Reduction in the Fertility of Hybrid Males." International Journal of Biology 12, no. 2 (March 30, 2020): 41. http://dx.doi.org/10.5539/ijb.v12n2p41.

Full text

Abstract:

There are several barriers to preclude the gene flow between diverging populations. On the basis of their temporal nature, these can be broadly categorized into two forms: pre- and post-zygotic. Post-zygotic reproductive isolation can manifest in the form of reductions in hybrid fertility. Keeping this fact in view, in the present study, we studied sterility in hybrids of D. ananassae and D. pallidosa. Surprisingly a distinguishable pattern of infertility was found in the hybrids. This pattern, referred to as Haldane’s rule, is often observed in hybrids of recently diverged populations or species. Reduction in the fertility of hybrids provides the clue of incipient kind of post-zygotic reproductive isolation in these two sibling species. This is the first report of hybrid sterility in this species pair. However, hybrid sterility is not very prominent especially when compared to that of other species pairs with the similar divergence time. Thus, on the basis of our results, we conclude that either sexual isolation between these sibling species is sufficient and does not require the aid of post-zygotic isolation to preclude gene flow or rate of divergence between D. ananassae and D. pallidosa is very slow in comparison to other species pair or even races of some species.

APA, Harvard, Vancouver, ISO, and other styles

17

McKee, Bruce D., Rihui Yan, and Jui-He Tsai. "Meiosis in male Drosophila." Spermatogenesis 2, no. 3 (July 2012): 167–84. http://dx.doi.org/10.4161/spmg.21800.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Giansanti, Maria Grazia, Stefano Sechi, Anna Frappaolo, Giorgio Belloni, and Roberto Piergentili. "Cytokinesis in Drosophila male meiosis." Spermatogenesis 2, no. 3 (July 2012): 185–96. http://dx.doi.org/10.4161/spmg.21711.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Garza, D., M. M. Medhora, and D. L. Hartl. "Drosophila nonsense suppressors: functional analysis in Saccharomyces cerevisiae, Drosophila tissue culture cells and Drosophila melanogaster." Genetics 126, no. 3 (November 1, 1990): 625–37. http://dx.doi.org/10.1093/genetics/126.3.625.

Full text

Abstract:

Abstract Amber (UAG) and opal (UGA) nonsense suppressors were constructed by oligonucleotide site-directed mutagenesis of two Drosophila melanogaster leucine-tRNA genes and tested in yeast, Drosophila tissue culture cells and transformed flies. Suppression of a variety of amber and opal alleles occurs in yeast. In Drosophila tissue culture cells, the mutant tRNAs suppress hsp70:Adh (alcohol dehydrogenase) amber and opal alleles as well as an hsp70:beta-gal (beta-galactosidase) amber allele. The mutant tRNAs were also introduced into the Drosophila genome by P element-mediated transformation. No measurable suppression was seen in histochemical assays for Adhn4 (amber), AdhnB (opal), or an amber allele of beta-galactosidase. Low levels of suppression (approximately 0.1-0.5% of wild type) were detected using an hsp70:cat (chloramphenicol acetyltransferase) amber mutation. Dominant male sterility was consistently associated with the presence of the amber suppressors.

APA, Harvard, Vancouver, ISO, and other styles

20

Heikkinen, Erja, and Jaakko Lumme. "Sterility of male and female hybrids of Drosophila virilis and Drosophila lummei." Heredity 67, no. 1 (August 1991): 1–11. http://dx.doi.org/10.1038/hdy.1991.58.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Shahandeh, Michael P., Alison Pischedda, Jason M. Rodriguez, and Thomas L. Turner. "The Genetics of Male Pheromone Preference Difference Between Drosophila melanogaster and Drosophila simulans." G3: Genes|Genomes|Genetics 10, no. 1 (November 20, 2019): 401–15. http://dx.doi.org/10.1534/g3.119.400780.

Full text

Abstract:

Species of flies in the genus Drosophila differ dramatically in their preferences for mates, but little is known about the genetic or neurological underpinnings of this evolution. Recent advances have been made to our understanding of one case: pheromone preference evolution between the species D. melanogaster and D. simulans. Males of both species are very sensitive to the pheromone 7,11-HD that is present only on the cuticle of female D. melanogaster. In one species this cue activates courtship, and in the other it represses it. This change in valence was recently shown to result from the modification of central processing neurons, rather than changes in peripherally expressed receptors, but nothing is known about the genetic changes that are responsible. In the current study, we show that a 1.35 Mb locus on the X chromosome has a major effect on male 7,11-HD preference. Unfortunately, when this locus is divided, the effect is largely lost. We instead attempt to filter the 159 genes within this region using our newfound understanding of the neuronal underpinnings of this phenotype to identify and test candidate genes. We present the results of these tests, and discuss the difficulty of identifying the genetic architecture of behavioral traits and the potential of connecting these genetic changes to the neuronal modifications that elicit different behaviors.

APA, Harvard, Vancouver, ISO, and other styles

22

Certel, S. J., M. G. Savella, D. C. F. Schlegel, and E. A. Kravitz. "Modulation of Drosophila male behavioral choice." Proceedings of the National Academy of Sciences 104, no. 11 (March 5, 2007): 4706–11. http://dx.doi.org/10.1073/pnas.0700328104.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Fujii, Shinsuke, Parthasarathy Krishnan, Paul Hardin, and Hubert Amrein. "Nocturnal Male Sex Drive in Drosophila." Current Biology 17, no. 3 (February 2007): 244–51. http://dx.doi.org/10.1016/j.cub.2006.11.049.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Hoyer, Susanne C., Andreas Eckart, Anthony Herrel, Troy Zars, Susanne A. Fischer, Shannon L. Hardie, and Martin Heisenberg. "Octopamine in Male Aggression of Drosophila." Current Biology 18, no. 3 (February 2008): 159–67. http://dx.doi.org/10.1016/j.cub.2007.12.052.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Zeng, L. W., and R. S. Singh. "The genetic basis of Haldane's rule and the nature of asymmetric hybrid male sterility among Drosophila simulans, Drosophila mauritiana and Drosophila sechellia." Genetics 134, no. 1 (May 1, 1993): 251–60. http://dx.doi.org/10.1093/genetics/134.1.251.

Full text

Abstract:

Abstract Haldane's rule (i.e., the preferential hybrid sterility and inviability of heterogametic sex) has been known for 70 years, but its genetic basis, which is crucial to the understanding of the process of species formation, remains unclear. In the present study, we have investigated the genetic basis of hybrid male sterility using Drosophila simulans, Drosophila mauritiana and Drosophila sechellia. An introgression of D. sechellia Y chromosome into a fairly homogenous background of D. simulans did not show any effect of the introgressed Y on male sterility. The substitution of D. simulans Y chromosome into D. sechellia, and both reciprocal Y chromosome substitutions between D. simulans and D. mauritiana were unsuccessful. Introgressions of cytoplasm between D. simulans and D. mauritiana (or D. sechellia) also did not have any effect on hybrid male sterility. These results rule out the X-Y interaction hypothesis as a general explanation of Haldane's rule in this species group and indicate an involvement of an X-autosome interaction. Models of symmetrical and asymmetrical X-autosome interaction have been developed which explain the Y chromosome substitution results and suggest that evolution of interactions between different genetic elements in the early stages of speciation is more likely to be of an asymmetrical nature. The model of asymmetrical X-autosome interaction also predicts that different sets of interacting genes may be involved in different pairs of related species and can account for the observation that hybrid male sterility in many partially isolated species is often nonreciprocal or unidirectional.

APA, Harvard, Vancouver, ISO, and other styles

26

Widemo, Fredrik, and Björn G. Johansson. "Male–male pheromone signalling in a lekking Drosophila." Proceedings of the Royal Society B: Biological Sciences 273, no. 1587 (December 6, 2005): 713–17. http://dx.doi.org/10.1098/rspb.2005.3379.

Full text

Abstract:

Interest in sex pheromones has mainly been focused on mate finding, while relatively little attention has been given to the role of sex pheromones in mate choice and almost none to competition over mates. Here, we study male response to male pheromones in the lekking Drosophila grimshawi , where males deposit long-lasting pheromone streaks that attract males and females to the leks and influence mate assessment. We used two stocks of flies and both stocks adjusted their pheromone depositing behaviour in response to experimental manipulation, strongly indicating male ability to distinguish between competitors from qualitative differences in pheromone streaks alone. This is the first example of an insect distinguishing between individual odour signatures. Pheromone signalling influenced competition over mates, as males adjusted their investment in pheromone deposition in response to foreign pheromone streaks. Both sexes adapt their behaviour according to information from olfactory cues in D. grimshawi , but the relative benefits from male–female, as compared to male–male signalling, remain unknown. It seems likely that the pheromone signalling system originally evolved for attracting females to leks. The transition to a signalling system for conveying information about individuals may well, however, at least in part have been driven by benefits from male–male signalling.

APA, Harvard, Vancouver, ISO, and other styles

27

Welbergen, PH, W. Scharloo, and F. R. VAN DIJKEN. "Collation of the Courtship Behaviour of the Sympatric Species Drosophila Melanogaster and Drosophila Simulans." Behaviour 101, no. 4 (1987): 253–74. http://dx.doi.org/10.1163/156853987x00017.

Full text

Abstract:

Abstract1. A female choice experiment between two stocks of the sibling species Drosophila melanogaster and D. simulans revealed a complete sexual isolation between the two species. 2. The courtship behaviour of males and females of the two species has been recorded in single pair matings by one observer using a microcomputer. It can be classified into the same 16 elements without stressing the species-typical aspects of the performances. 3. A detailed comparison of four courtship parameters per behavioural element, (I) percentage of total number of courtship acts, (II) percentage of total courtship time, (III) mean boutlength, and (IV) mean frequency per minute, showed a substantial quantitative differentiation of both sexes between the two closely-related species. 4. Drosophila simulans males and females are both less active in performing their behaviours than D. melanogaster. Scissoring is the major type of wingdisplay in the courtship of D. simulans males, and vibration is more common in the courtship of D. melanogaster males. Drosophila simulans females show lower frequencies per minute of all elements, except walking, extruding, and flicking. 5. Courtship duration in D. melanogaster males is controlled by the elements: orientation, following, and attempted copulation, as was shown by correlation analysis. In D. simulans males, courtship duration is mainly controlled by the elements licking and attempted copulation. However, with respect to the correlation coefficients of individual male behaviours the two species do not differ significantly. Therefore, we could not single out decisive and distinctive elements for enhancement of female's receptivity as a discriminating feature of male sexual behaviour of the two species. 6. First-order sequential analysis of intra-male dyadic transitions between adjacent behaviour elements of D. melanogaster and D. simulans shows quantitative differences primarily in transitions with either vibration or scissoring as the preceding or succeeding acts. Differences between the two female species are mainly limited to transitions in which the rejection-movements decamping and kicking are involved. 7. Analysis of inter-individual dyadic sequences gives the communicative value of male elements relative to the female elements and vice versa. In the communicative interactions with females, scissoring is the major type of wingdisplay in D. simulans males. It accomplishes the same role either in responding to the female or in stimulating the female as vibration does in D. melanogaster males. The elements standing, preening, and extruding are the central behaviours of females in both species in elucidating the male elements orientation, major type of wingdisplay, licking, and attempted copulation. However, the degree to which these male elements are initiated by the female's elements differs quantitatively between the two species. These quantitative differences emphasizes the differentiation in patterns of interaction between sexes between the two species.

APA, Harvard, Vancouver, ISO, and other styles

28

Hoffmann, Ary A., and Lawrence G. Harshman. "Male Effects on Fecundity in Drosophila melanogaster." Evolution 39, no. 3 (May 1985): 638. http://dx.doi.org/10.2307/2408658.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Hoffmann, Ary A., and Lawrence G. Harshman. "MALE EFFECTS ON FECUNDITY IN DROSOPHILA MELANOGASTER." Evolution 39, no. 3 (May 1985): 638–44. http://dx.doi.org/10.1111/j.1558-5646.1985.tb00400.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Montenegro, H., V. N. Solferini, L. B. Klaczko, and G. D. D. Hurst. "Male-killing Spiroplasma naturally infecting Drosophila melanogaster." Insect Molecular Biology 14, no. 3 (April 26, 2005): 281–87. http://dx.doi.org/10.1111/j.1365-2583.2005.00558.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Wu, Chia-Lin, Tsai-Feng Fu, Meng-Hsuan Chiang, Yu-Wei Chang, Jim-Long Her, and Tony Wu. "Magnetoreception Regulates Male Courtship Activity in Drosophila." PLOS ONE 11, no. 5 (May 19, 2016): e0155942. http://dx.doi.org/10.1371/journal.pone.0155942.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Santos-Colares, Marisa C. Dos, Vera L. S. Valente, and Beatriz Goñi. "The meiotic chromosomes of male Drosophila willistoni." Caryologia 56, no. 4 (January 2003): 431–37. http://dx.doi.org/10.1080/00087114.2003.10589355.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Singh, BN, and S. Chatterjee. "Rare-male mating advantage in Drosophila ananassae." Genetics Selection Evolution 21, no. 4 (1989): 447. http://dx.doi.org/10.1186/1297-9686-21-4-447.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Bachtrog, D. "Evidence for Male-Driven Evolution in Drosophila." Molecular Biology and Evolution 25, no. 4 (February 14, 2008): 617–19. http://dx.doi.org/10.1093/molbev/msn020.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Edmunds, Danielle, Stuart Wigby, and Jennifer C. Perry. "‘Hangry’ Drosophila: food deprivation increases male aggression." Animal Behaviour 177 (July 2021): 183–90. http://dx.doi.org/10.1016/j.anbehav.2021.05.001.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Lizé, Anne, Rowan J. Doff, Eve A. Smaller, Zenobia Lewis, and Gregory D. D. Hurst. "Perception of male–male competition influences Drosophila copulation behaviour even in species where females rarely remate." Biology Letters 8, no. 1 (July 13, 2011): 35–38. http://dx.doi.org/10.1098/rsbl.2011.0544.

Full text

Abstract:

Males in many taxa are known to exhibit behavioural plasticity in response to the perceived intensity of sperm competition, reflected in Drosophila melanogaster by increased copulation duration following prior exposure to a rival. We tested the prediction that males do not adjust their copulation effort in response to the presence of a competitor in Drosophila species where there is little or no sperm competition. Contrary to expectations, male plasticity in copulation duration was found in both Drosophila subobscura and Drosophila acanthoptera , species in which females rarely remate. These results are discussed in relation to the adaptive basis of plasticity in these species.

APA, Harvard, Vancouver, ISO, and other styles

37

Liu, T., L. Dartevelle, C. Yuan, H. Wei, Y. Wang, J. F. Ferveur, and A. Guo. "Increased Dopamine Level Enhances Male-Male Courtship in Drosophila." Journal of Neuroscience 28, no. 21 (May 21, 2008): 5539–46. http://dx.doi.org/10.1523/jneurosci.5290-07.2008.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Wang, F., M. Hanske, K. Miedema, G. Klein, P. Ekblom, and W. Hennig. "Laminin in the male germ cells of Drosophila." Journal of Cell Biology 119, no. 4 (November 15, 1992): 977–88. http://dx.doi.org/10.1083/jcb.119.4.977.

Full text

Abstract:

To study genes that may be crucial for the male germ cell development of Drosophila we screened a cDNA expression library with a polyclonal antiserum against testis proteins of Drosophila hydei. We identified a cDNA fragment that exhibited a complete sequence similarity with the cDNA of the laminin B2 chain, an important component of the extracellular matrix. Transcripts of laminin B2 were detected in the RNA of male germ cells with the polymerase chain reaction and by in situ hybridization. We studied the reaction of different polyclonal antibodies including those against a Drosophila laminin B2-lac fusion protein, the entire Drosophila laminin complex, or against the mouse laminin complex and against laminin A and B1 chains with specific structures in developing male germ cells of Drosophila. Antigenic sites against laminin B2 were found in the lampbrush loops in primary spermatocyte nuclei, in nuclei of spermatids, and in heads of spermatozoa. The axonemes of elongating spermatids react with antibodies against the Drosophila laminin B1, B2 and laminin A chains. The possible biological functions of the laminin in the male germ cells of Drosophila are discussed.

APA, Harvard, Vancouver, ISO, and other styles

39

Noor, Mohamed A. F. "Genetics of Sexual Isolation and Courtship Dysfunction in Male Hybrids of Drosophila pseudoobscura and Drosophila persimilis." Evolution 51, no. 3 (June 1997): 809. http://dx.doi.org/10.2307/2411156.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

True, John R., Jianjun Liu, Lynn F. Stam, Zhao-Bang Zeng, and Cathy C. Laurie. "Quantitative Genetic Analysis of Divergence in Male Secondary Sexual Traits Between Drosophila simulans and Drosophila mauritiana." Evolution 51, no. 3 (June 1997): 816. http://dx.doi.org/10.2307/2411157.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Veneti, Z., S. Zabalou, G. Papafotiou, C. Paraskevopoulos, S. Pattas, I. Livadaras, G. Markakis, J. K. Herren, J. Jaenike, and K. Bourtzis. "Loss of reproductive parasitism following transfer of male-killing Wolbachia to Drosophila melanogaster and Drosophila simulans." Heredity 109, no. 5 (August 15, 2012): 306–12. http://dx.doi.org/10.1038/hdy.2012.43.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Noor, Mohamed A. F. "GENETICS OF SEXUAL ISOLATION AND COURTSHIP DYSFUNCTION IN MALE HYBRIDS OF DROSOPHILA PSEUDOOBSCURA AND DROSOPHILA PERSIMILIS." Evolution 51, no. 3 (June 1997): 809–15. http://dx.doi.org/10.1111/j.1558-5646.1997.tb03663.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

True, John R., Jianjun Liu, Lynn F. Stam, Zhao-Bang Zeng, and Cathy C. Laurie. "QUANTITATIVE GENETIC ANALYSIS OF DIVERGENCE IN MALE SECONDARY SEXUAL TRAITS BETWEEN DROSOPHILA SIMULANS AND DROSOPHILA MAURITIANA." Evolution 51, no. 3 (June 1997): 816–32. http://dx.doi.org/10.1111/j.1558-5646.1997.tb03664.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Pruett-Jones, Stephen, Matthew Deangelis, Carina Gronlund, Philip Ward, and Jerry Coyne. "Mate grasping in drosophila pegasa by." Behaviour 139, no. 4 (2002): 545–72. http://dx.doi.org/10.1163/15685390260136005.

Full text

Abstract:

AbstractAmong all species in the genus Drosophila whose sexual behavior has been studied, D. pegasa is unique in that males exhibit no courtship behaviour before they mount females. Instead, the male simply climbs on top of the female and rides on her abdomen ('grasping') for long intervals, often an entire 8-h observation period. In this study we conducted a series of observations and experiments to quantitatively describe grasping behaviour in D. pegasa and examine its relationship to social environment and the reproductive biology of the species. All observed courtship bouts involved grasping behavior, and males always initiated copulation during a grasping bout. The frequency of grasping and the average duration of a single grasping bout increased with the number of flies present. Males often copulated several times during a single grasping bout, and such multiple copulations during a single mounting also appear unique in the genus. Unexpectedly, the number of sperm that a male transferred to a female during a single grasping bout was negatively correlated with the number of copulations. This relationship was apparently due to repeated copulations by males who were unsuccessful at transferring sperm. Multiple copulations without sperm transfer may result from cryptic female choice. Male grasping behaviour in this species appears to have evolved as a substitute for display and courtship behaviours, but possibly also as a mate-guarding behaviour since males continue to grasp after they have successfully transferred sperm. The tarsal claws and pulvillar pads of D. pegasa are disproportionately larger than those of related Drosophila species, evolutionary changes that may facilitate grasping by males.

APA, Harvard, Vancouver, ISO, and other styles

45

MAGNACCA, KARL N., and DONALD K. PRICE. "New species of Hawaiian picture wing Drosophila (Diptera: Drosophilidae), with a key to species." Zootaxa 3188, no. 1 (February 9, 2012): 1. http://dx.doi.org/10.11646/zootaxa.3188.1.1.

Full text

Abstract:

The picture wing species group of Hawaiian Drosophila is the only one to be relatively well known taxonomically, butspecies continue to be discovered. Here seven new species are described: Drosophila kikiko new species, Drosophila ki-noole new species, Drosophila moli new species, Drosophila nukea new species, Drosophila opuhe new species, Dros-ophila pihulu new species, and Drosophila pilipa new species. In addition, the male of Drosophila oreas Hardy isdescribed for the first time, and Drosophila virgulata Hardy & Kaneshiro is reduced to a new junior synonym of Dros-ophila lanaiensis Grimshaw, and the status of the latter and Drosophila ciliaticrus Hardy is clarified. A complete key to all the picture wing species is provided.

APA, Harvard, Vancouver, ISO, and other styles

46

Sawamura, Kyoichi, John Roote, Chung-I. Wu, and Masa-Toshi Yamamoto. "Genetic Complexity Underlying Hybrid Male Sterility in Drosophila." Genetics 166, no. 2 (February 2004): 789–96. http://dx.doi.org/10.1534/genetics.166.2.789.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Sawby, Ryan, and Kimberly A. Hughes. "MALE GENOTYPE AFFECTS FEMALE LONGEVITY IN DROSOPHILA MELANOGASTER." Evolution 55, no. 4 (2001): 834. http://dx.doi.org/10.1554/0014-3820(2001)055[0834:mgafli]2.0.co;2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Clowney, E. Josephine, Shinya Iguchi, Jennifer J. Bussell, Elias Scheer, and Vanessa Ruta. "Multimodal Chemosensory Circuits Controlling Male Courtship in Drosophila." Neuron 87, no. 5 (September 2015): 1036–49. http://dx.doi.org/10.1016/j.neuron.2015.07.025.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Partridge, Linda, Trudy F. C. Mackay, and Susan Aitken. "Male mating success and fertility in Drosophila melanogaster." Genetical Research 46, no. 3 (December 1985): 279–85. http://dx.doi.org/10.1017/s0016672300022783.

Full text

Abstract:

SUMMARYThe male mating ability and male fertility of 40 third chromosome homozygote lines has been measured. There was significant between-line differentiation for both characters, and comparison with a heterozygous stock indicated inbreeding depression and hence dominance variation for them. The characters showed significant positive correlation both with each other and with other fitness components and total fitness, as measured by Mackay (1985). This pattern of large positive correlations between fitness components is not expected to occur in outbred populations.

APA, Harvard, Vancouver, ISO, and other styles

50

Sawby, Ryan, and Kimberly A. Hughes. "MALE GENOTYPE AFFECTS FEMALE LONGEVITY IN DROSOPHILA MELANOGASTER." Evolution 55, no. 4 (May 9, 2007): 834–39. http://dx.doi.org/10.1111/j.0014-3820.2001.tb00819.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!